Journal of tissue viability最新文献

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What specific challenges do patients with chronic wounds encounter when attending medical appointments related to wound care? A systematic review 慢性伤口患者在参加与伤口护理相关的医疗预约时遇到哪些具体挑战?系统回顾
IF 2.4 3区 医学
Journal of tissue viability Pub Date : 2025-02-03 DOI: 10.1016/j.jtv.2025.100865
Krishi Jain , Pinar Avsar , Declan Patton , Zena Moore , Bridget Murray
{"title":"What specific challenges do patients with chronic wounds encounter when attending medical appointments related to wound care? A systematic review","authors":"Krishi Jain ,&nbsp;Pinar Avsar ,&nbsp;Declan Patton ,&nbsp;Zena Moore ,&nbsp;Bridget Murray","doi":"10.1016/j.jtv.2025.100865","DOIUrl":"10.1016/j.jtv.2025.100865","url":null,"abstract":"<div><h3>Background</h3><div>Chronic wounds can pose a significant challenge for patients and healthcare professionals including the morbidity and associated costs. It is therefore essential to understand the specific challenges faced by patients to make wound care services more effective and convenient for the patient population.</div></div><div><h3>Aim</h3><div>Using the PEO model, this systematic review aims to explore the specific challenges patients with chronic wounds encounter when attending medical appointments related to wound care.</div></div><div><h3>Method</h3><div>A systematic search of publications using MEDLINE, Ovid EMBASE, CINAHL databases was conducted in April 2024, and relevant articles were reviewed. Data extraction and a narrative synthesis approach was undertaken. The evidence-based librarianship (EBL) checklist assessed the methodological quality of the studies included. The primary outcome was to identify the specific challenges faced by patients with chronic wounds who attend medical appointments related to wound care. The secondary outcome was to determine wound healing progression, quality of life, complications of wound care, and adverse effects of wound care.</div></div><div><h3>Results</h3><div>Six studies between the years 2014 and 2024 described the specific challenges faced by patients with chronic wounds in a hospital or clinic setting. All six studies mentioned the pain and unwanted physical inactivity collectively affected the daily life of the patients and their capability of attending appointments. Increased cost of attending wound care appointments and travelling were elucidated by four studies. Increased waiting time during the appointments were also described by four studies. Additionally, two studies mentioned the difficulties of accessing public transport and heavy reliance on private transport because of the physical inability associated with the wound.</div></div><div><h3>Conclusion</h3><div>This systematic review identified several challenges faced by patients with chronic wounds when attending medical appointments. Key issues include increased waiting times, and the excessive cost of appointments. Pain, discomfort, and physical limitations further complicated attendance, particularly for distant clinics, leading to reliance on expensive private transport. Additionally, three studies reported decreased quality of life. These findings highlight the need for more effective and convenient wound care services for patients.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100865"},"PeriodicalIF":2.4,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143436470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence, risk level and risk factors of diabetic foot ulcer among adult individuals with diabetes in the Southeastern Anatolia Region of Turkiye 土耳其安纳托利亚东南部地区成人糖尿病患者糖尿病足溃疡的患病率、危险水平和危险因素
IF 2.4 3区 医学
Journal of tissue viability Pub Date : 2025-02-01 DOI: 10.1016/j.jtv.2024.12.003
Meryem Kilic , Nermin Olgun , Mehmet Dündar , Sergül Celik Advan , Fatma Zehra Kücük , Seher Okcuoglu , Sevim Sahin , Emine Kır Bicer , Yeliz Ülker , Pınar Sahin , Zeynep Taskiran
{"title":"Prevalence, risk level and risk factors of diabetic foot ulcer among adult individuals with diabetes in the Southeastern Anatolia Region of Turkiye","authors":"Meryem Kilic ,&nbsp;Nermin Olgun ,&nbsp;Mehmet Dündar ,&nbsp;Sergül Celik Advan ,&nbsp;Fatma Zehra Kücük ,&nbsp;Seher Okcuoglu ,&nbsp;Sevim Sahin ,&nbsp;Emine Kır Bicer ,&nbsp;Yeliz Ülker ,&nbsp;Pınar Sahin ,&nbsp;Zeynep Taskiran","doi":"10.1016/j.jtv.2024.12.003","DOIUrl":"10.1016/j.jtv.2024.12.003","url":null,"abstract":"<div><h3>Objective</h3><div>The aim of the study was to determine the prevalence, risk, and predisposing factors of diabetic foot ulcers in adults with diabetes.</div></div><div><h3>Methods</h3><div>This study is multi-centered descriptive cross-sectional research. Data were collected between June 2022 and November 2022 in seven cities, including five teaching and research hospitals and two public hospitals. The study included 357 people with diabetes. The sample was selected using stratified and systematic sampling. General demographic characteristics, medical history, laboratory and foot examination results, history of foot ulcer and/or amputation, skin and nail problems, peripheral sensory loss (10 g-Semmes-Weinstein monofilament) and vascular assessment were obtained. Logistic regression analysis was used to screen for factors affecting the diabetic foot.</div></div><div><h3>Results</h3><div>The prevalence of diabetic foot ulcers was 17.1 % (%13.2-%21.5; %95 CI). Among 296 individuals with diabetes without foot ulcers, 86.5 % (256) had risk level 0, 7.3 % (26) had risk level 1, 3.4 % (10) had risk level 2, and 1.4 % (4) had risk level 3. In regression analysis, the variables of peripheral arterial disease (Exp β: 3.781 - P = .027), history of ulcer (Exp β = 26,180 - P &lt; .001), edema (Exp β: 9.784 - P &lt; .001), fungus between the toes (Exp β = 5.284 - p = .009) were associated with a significantly increased risk of developing diabetic foot.</div></div><div><h3>Conclusion</h3><div>The prevalence of diabetic foot ulcers was found to be approximately two out of every 10 patients with diabetes, and peripheral arterial disease, history of ulcers, edema, and presence of fungus between the toes were found to be among the risks predicting diabetic foot. All diabetic individuals should be diagnosed in terms of diabetic foot risk factors, and follow-up and treatment should be planned considering the basic building blocks of diabetic foot prevention according to the determined risk group.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 1","pages":"Article 100839"},"PeriodicalIF":2.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determining the quality of life and associated factors in patients with pressure injury 确定压伤患者的生活质量及相关因素。
IF 2.4 3区 医学
Journal of tissue viability Pub Date : 2025-02-01 DOI: 10.1016/j.jtv.2024.11.007
Şenay Gül , Ayşe Sılanur Demir , Ayişe Karadağ , Pelin Karaçay
{"title":"Determining the quality of life and associated factors in patients with pressure injury","authors":"Şenay Gül ,&nbsp;Ayşe Sılanur Demir ,&nbsp;Ayişe Karadağ ,&nbsp;Pelin Karaçay","doi":"10.1016/j.jtv.2024.11.007","DOIUrl":"10.1016/j.jtv.2024.11.007","url":null,"abstract":"<div><h3>Aim</h3><div>This study aimed to determine the quality of life of patients with pressure injuries and the factors associated with them.</div></div><div><h3>Materials and methods</h3><div>This descriptive and correlative study was conducted between January 2022 and July 2023 at one private and two state hospitals in Türkiye. Data were collected using a demographic and clinical history form, the Pressure Ulcer Quality of Life Scale- Turkish.</div></div><div><h3>Results</h3><div>In this study, the mean quality of life score of the patients with pressure injuries was 65.28 ± 12.71, and according to the Pressure Ulcer Quality of Life Scale- Turkish score of the patients, the areas with the worst quality of life were mobility and movement, activity, pain, sleep, odor, and exudate, respectively. The most important variables that negatively affected the quality of life were determined to be the number of pressure injuries, prolonged healing time, and diagnosis of diabetes. In contrast, the variable that positively affected the quality of life was determined as having had any previous surgical experience.</div></div><div><h3>Conclusion</h3><div>It is recommended that the results obtained from this study should be utilized in determining national and institutional strategies to improve the quality of life of patients with pressure injuries and that interventional studies should be planned to improve the quality of life of patients with pressure injuries.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 1","pages":"Article 100835"},"PeriodicalIF":2.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142755278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differences on lower trapezius pressure pain threshold, muscle strength and muscle thickness in individuals with chronic neck pain and active or latent myofascial triggers points 慢性颈部疼痛和活跃或潜在肌筋膜触发点个体下斜方肌压力痛阈、肌肉力量和肌肉厚度的差异
IF 2.4 3区 医学
Journal of tissue viability Pub Date : 2025-02-01 DOI: 10.1016/j.jtv.2024.12.008
Irene Redondo-Orúe , Sara Sánchez-Baena , Almudena Paret-Fernández , Isabel Rodríguez-Costa , Carlos Romero Morales , Daniel López-López , Daniel Pecos-Martín , Ángel González de la Flor
{"title":"Differences on lower trapezius pressure pain threshold, muscle strength and muscle thickness in individuals with chronic neck pain and active or latent myofascial triggers points","authors":"Irene Redondo-Orúe ,&nbsp;Sara Sánchez-Baena ,&nbsp;Almudena Paret-Fernández ,&nbsp;Isabel Rodríguez-Costa ,&nbsp;Carlos Romero Morales ,&nbsp;Daniel López-López ,&nbsp;Daniel Pecos-Martín ,&nbsp;Ángel González de la Flor","doi":"10.1016/j.jtv.2024.12.008","DOIUrl":"10.1016/j.jtv.2024.12.008","url":null,"abstract":"<div><h3>Background</h3><div>Myofascial trigger points (MTrPs) in the lower trapezius have been recognized as an important source of neck pain. This study aims to compare the lower trapezius muscle strength, pressure pain threshold (PPT) and muscle thickness at rest and contraction between participants and painful vs. no-painful side with active and latent MTrPs; and to examine the associations among these variables with pain intensity, duration and disability in patients with neck pain.</div></div><div><h3>Methods</h3><div>A cross-sectional study was carried out in 64 people with neck pain with active or latent MTrPs (34 Active MTrPs group and 30 Latent MTrPs groups). Muscle strength, pressure pain threshold and muscle thickness at rest and contraction of the lower trapezius was recorded.</div></div><div><h3>Results</h3><div>No significant differences were found in descriptive data, dominant side, or side of neck pain. However, the Active MTrPs Group had lower pain pressure thresholds (PPT) on the neck pain side compared to the Latent MTrPs Group, indicating greater sensitivity. Muscle thickness and strength showed minor differences between groups. Pain intensity correlated moderately with pain duration and strongly with neck pain disability.</div></div><div><h3>Conclusions</h3><div>The results of the present study showed differences in PPT on the lower trapezius muscle in active and latent MTrP in neck side pain compared to non-neck side pain. In addition, lower trapezius strength reported differences between the neck side pain compared to non-neck side pain in both active and latent MTrP. Lower trapezius muscle strength showed significant moderate association with muscle thickness at contraction.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 1","pages":"Article 100844"},"PeriodicalIF":2.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142895954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
“I was surprised that the veins were the cause” – The illness trajectory of people with venous leg ulcers: A qualitative study “我很惊讶静脉是病因”——腿部静脉性溃疡患者的疾病轨迹:一项定性研究。
IF 2.4 3区 医学
Journal of tissue viability Pub Date : 2025-02-01 DOI: 10.1016/j.jtv.2024.12.001
Robin Schick , Caroline Staub-Buset , Gabriel Vujic , Sina Lachappelle , Eva-Maria Panfil
{"title":"“I was surprised that the veins were the cause” – The illness trajectory of people with venous leg ulcers: A qualitative study","authors":"Robin Schick ,&nbsp;Caroline Staub-Buset ,&nbsp;Gabriel Vujic ,&nbsp;Sina Lachappelle ,&nbsp;Eva-Maria Panfil","doi":"10.1016/j.jtv.2024.12.001","DOIUrl":"10.1016/j.jtv.2024.12.001","url":null,"abstract":"<div><h3>Background</h3><div>Patients with venous leg ulcers (VLUs) often carry out inadequate self-care. Person-centered care is recommended as effective support. Understanding the illness trajectory from the patient's perspective could be a way to better understand patients' needs.</div></div><div><h3>Aim</h3><div>The aim was to describe the illness trajectory experienced by patients with venous leg ulcers.</div></div><div><h3>Methods</h3><div>Using a qualitative approach, we conducted individual interviews with a purposive sample of 12 patients with venous leg ulcers in the wound outpatient department of a university hospital. Thematic analysis was carried out utilizing the Illness Trajectory Model as the theoretical framework.</div></div><div><h3>Results</h3><div>8 women and 4 men with an average age of 74 years had different wound durations, recurrence rates and comorbidities. We identified six illness trajectory-relevant phases: (1) “Accident” or “mosquito bite”; (2) Experiential knowledge reaches its limits; (3) Seeking professional help; (4) Help from the wound clinic; (5) Saying goodbye to normality; (6) Managing VLU in everyday life. VLUs were often caused by accidents and initially treated by patients themselves, with medical help sought later. Over time, patients adapted to treatments like compression therapy, gained self-management (SM) skills to cope with daily life challenges.</div></div><div><h3>Conclusion</h3><div>All participants performed SM to varying degrees, but not always adequately. Insufficient awareness of the wound as a symptom and complication of a causative disease caused inadequate and ineffective wound management in many cases. Adequate SM developed primarily through learning from experience. The promotion of empirical knowledge and needs-oriented education can improve the SM of affected persons.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 1","pages":"Article 100837"},"PeriodicalIF":2.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Turkish nurses' knowledge, attitudes and practices in the management of incontinence associated dermatitis: A descriptive and cross-sectional study 土耳其护士的知识,态度和做法在失禁相关性皮炎的管理:描述性和横断面研究。
IF 2.4 3区 医学
Journal of tissue viability Pub Date : 2025-02-01 DOI: 10.1016/j.jtv.2024.12.005
Münevver Sönmez , Öznur Gürlek Kısacık , Serap Korkmaz
{"title":"Turkish nurses' knowledge, attitudes and practices in the management of incontinence associated dermatitis: A descriptive and cross-sectional study","authors":"Münevver Sönmez ,&nbsp;Öznur Gürlek Kısacık ,&nbsp;Serap Korkmaz","doi":"10.1016/j.jtv.2024.12.005","DOIUrl":"10.1016/j.jtv.2024.12.005","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to determine nurses' current knowledge, attitudes, and practices in adult intensive care units and palliative care clinics regarding incontinence-associated dermatitis (IAD).</div></div><div><h3>Materials and methods</h3><div>This descriptive cross-sectional study was conducted with 355 nurses in adult intensive care and palliative services at two hospitals. Data were collected between 5.03.2022 and 15.06.2022 using the” Nurse Demographic Form” and the “Knowledge, Attitude and Practice of Nurses in Managing Incontinence-Associated Dermatitis Questionnaire”.</div></div><div><h3>Results</h3><div>The nurses' mean scores for \"Knowledge of IAD Etiology and Diagnosis\" were 19.11 (SD 3.29), mean scores for \"Knowledge of IAD Risk Factors\" were 23.82 (SD 4.27), mean scores for \"Attitude Toward IAD Prevention\" were 10.1 (SD 2.49), and mean scores for \"Practices for IAD Prevention\" were 23.71 (SD 3.97). It was found that nurses who used a risk assessment tool to diagnose IAD (p = 0.001), had a procedure or protocol (p = 0.001), and received training on IAD (p &lt; 0.001) had significantly higher \"Attitude Towards Prevention of IAD\" scores. There was a positive correlation between the number of patients with IAD cared for by the nurses participating in the study and the scores of ''Practices to Prevent IAD'' and ''Knowledge of IAD Risk Factors'', ''Knowledge of IAD Etiology and Diagnosis'' and ''Attitude Towards Preventing IAD'' (p &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>This study found that intensive care and palliative care nurses' knowledge, attitudes, and practices regarding IAD were insufficient. Considering that IAD is encountered more frequently in these units, it is essential to provide continuous and practical training to nurses about IAD, use risk assessment tools to prevent and treat IAD, determine protocols, establish clinical guidelines, and implement and standardize them.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 1","pages":"Article 100841"},"PeriodicalIF":2.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to “Factors associated with adherence to prevention guidelines of pressure injuries among Jordanian nurses in critical care units”, [Journal of Tissue Viability, 34(1), February 2025, 100853] 《约旦重症监护室护士对压力伤害预防指南的遵守相关因素》的更正,[Journal of Tissue Viability, 34(1), 2025年2月,100853]。
IF 2.4 3区 医学
Journal of tissue viability Pub Date : 2025-02-01 DOI: 10.1016/j.jtv.2025.100859
Eslam Alalawneh , Raghad Abdelkader , Abdulkareem Iblasi , Osama Alkouri , Mohanad abu ruz , Anas Ababneh
{"title":"Corrigendum to “Factors associated with adherence to prevention guidelines of pressure injuries among Jordanian nurses in critical care units”, [Journal of Tissue Viability, 34(1), February 2025, 100853]","authors":"Eslam Alalawneh ,&nbsp;Raghad Abdelkader ,&nbsp;Abdulkareem Iblasi ,&nbsp;Osama Alkouri ,&nbsp;Mohanad abu ruz ,&nbsp;Anas Ababneh","doi":"10.1016/j.jtv.2025.100859","DOIUrl":"10.1016/j.jtv.2025.100859","url":null,"abstract":"","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 1","pages":"Article 100859"},"PeriodicalIF":2.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143007568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors associated with adherence to prevention guidelines of pressure injuries among Jordanian nurses in critical care units 与约旦重症监护室护士遵守压力伤害预防指南相关的因素。
IF 2.4 3区 医学
Journal of tissue viability Pub Date : 2025-02-01 DOI: 10.1016/j.jtv.2025.100853
Eslam Alalawneh , Raghad Abdelkader , Abdulkareem Iblasi , Osama Alkouri , Mohannad Aburuz , Anas Ababneh
{"title":"Factors associated with adherence to prevention guidelines of pressure injuries among Jordanian nurses in critical care units","authors":"Eslam Alalawneh ,&nbsp;Raghad Abdelkader ,&nbsp;Abdulkareem Iblasi ,&nbsp;Osama Alkouri ,&nbsp;Mohannad Aburuz ,&nbsp;Anas Ababneh","doi":"10.1016/j.jtv.2025.100853","DOIUrl":"10.1016/j.jtv.2025.100853","url":null,"abstract":"<div><h3>Background</h3><div>Pressure injury (PI) is a significant health issue and one of the greatest challenges in critical care units. Guidelines adherence to prevent PIs is not always optimal by critical care nurses. To our knowledge, there is no data about adherence to PI preventive guidelines among Jordanian critical care nurses, and this study aimed to fill this gap.</div></div><div><h3>Purpose</h3><div>To assess the levels of adherence, and factors associated with adherence to PIs prevention guidelines among critical care nurses in Jordan.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted among 269 nurses selected from four hospitals in Amman-Jordan. Multiple socio-demographic and psychosocial factors were collected including nurses' knowledge and attitudes toward PI prevention. A valid and reliable self-reported questionnaire (questionnaire to evaluate nurses' adherence to recommendations for preventing pressure ulcers QARPPU) was used to assess participants’ adherence to PIs prevention guidelines. Multiple linear regression was conducted to predict the factors associated with adherence to PI prevention guidelines.</div></div><div><h3>Results</h3><div>Nurses reported a mean of 58.2 ± 8.2 (90 is the highest score) of the total score of adherence scale indicating 65 % of adherence to PIs prevention guidelines. Factors independently associated with lower adherence were being a male nurse, absence of a policy of PI prevention, and being a nurse in a non-accredited hospital (all <em>p</em> ≤ 0.05).</div></div><div><h3>Conclusion</h3><div>Critical care nurses in Jordan do not have optimal adherence to PIs prevention guidelines. Implementing healthcare policies about PIs prevention and hospital accreditation seems to be essential to enhance their adherence.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 1","pages":"Article 100853"},"PeriodicalIF":2.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A novel skin-like patch based on 3D hydrogel nanocomposite of Polydopamine/TiO2 nanoparticles and Ag quantum dots accelerates diabetic wound healing compared to stem cell therapy 与干细胞治疗相比,基于聚多巴胺/TiO2纳米颗粒和银量子点的3D水凝胶纳米复合材料的新型皮肤样贴片加速了糖尿病伤口愈合。
IF 2.4 3区 医学
Journal of tissue viability Pub Date : 2025-02-01 DOI: 10.1016/j.jtv.2024.12.014
Sally A. Elekhtiar , Maha M. Abo Gazia , Amira Osman , Marwa M. Abd-Elsalam , Nesma M. El-Kemary , Samar Elksass , Hend A. Alkabes , Maged El-Kemary
{"title":"A novel skin-like patch based on 3D hydrogel nanocomposite of Polydopamine/TiO2 nanoparticles and Ag quantum dots accelerates diabetic wound healing compared to stem cell therapy","authors":"Sally A. Elekhtiar ,&nbsp;Maha M. Abo Gazia ,&nbsp;Amira Osman ,&nbsp;Marwa M. Abd-Elsalam ,&nbsp;Nesma M. El-Kemary ,&nbsp;Samar Elksass ,&nbsp;Hend A. Alkabes ,&nbsp;Maged El-Kemary","doi":"10.1016/j.jtv.2024.12.014","DOIUrl":"10.1016/j.jtv.2024.12.014","url":null,"abstract":"<div><div>Despite the advances in the development of therapeutic wearable wound-healing patches, lack self-healing properties and strong adhesion to diabetic skin, hindering their effectiveness. We propose a unique, wearable patch made from a 3D organo-hydrogel nanocomposite containing polydopamine, titanium dioxide nanoparticles, and silver quantum dots (PDA–TiO<sub>2</sub>@Ag). The designed patch exhibits ultra-stretchable, exceptional-self-healing, self-adhesive, ensuring conformal contact with the skin even during movement. Our patch demonstrated potent antibacterial activity and significantly accelerated wound healing with a high wound closure rate of 99.2 % after 7 days. Remarkably, it enhanced diabetic skin wound healing compared to that achieved by adipose-derived stem cell (ADSC) therapy in a study involving 30 adult male albino rats. Microscopic analysis highlights the promising hierarchical architecture structure of the patch for wound healing applications, suggesting its potential to create a favorable environment for healing and provide long-lasting benefits. Histopathological analysis and immunohistochemical staining revealed faster healing and enhanced cellular response in the patch-treated group compared to both stem cell and control groups. Notably, the patch promoted complete re-epithelization and a significant increase in vascular endothelial growth factor (VEGF) expression on day 7, indicating improved angiogenesis. This self-healing, multifunctional patch offers a promising alternative to stem cell therapy for accelerating diabetic wound healing, showcasing its potential for clinical translation. The combination of durability, biocompatibility, and antibacterial properties makes the patch a promising candidate for advanced wound management and offering faster, more complete restoration than other approaches.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 1","pages":"Article 100850"},"PeriodicalIF":2.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142895952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of hydrocolloid tape and facial massage on nasal injury and stress levels in premature infants on noninvasive mechanical ventilation: Randomized controlled trial 水胶体贴和面部按摩对无创机械通气早产儿鼻损伤和应激水平的影响:随机对照试验。
IF 2.4 3区 医学
Journal of tissue viability Pub Date : 2025-02-01 DOI: 10.1016/j.jtv.2024.12.006
Dilara Cengiz , Dilek Küçük Alemdar
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