Journal of tissue viability最新文献

{"title":"Randomized clinical trial of the efficacy of the EmoLED medical device in the treatment of stage 2 and stage 3 pressure ulcers: The RISE_UP study","authors":"Hamilton Dollaku ,&nbsp;Mara Dalladonna ,&nbsp;Marika Giuliano ,&nbsp;Michele Rossi ,&nbsp;Paola Barbetti ,&nbsp;Maria Sipontina Marcolongo ,&nbsp;Emanuele Buccione ,&nbsp;Paolo Iovino ,&nbsp;Claudio Macchi","doi":"10.1016/j.jtv.2025.100895","DOIUrl":"10.1016/j.jtv.2025.100895","url":null,"abstract":"<div><h3>Aim of the study</h3><div>Pressure ulcers are an important public health issue, impacting quality of life and causing health deterioration. Blue light photobiomodulation has been shown promoting wound healing in vascular, diabetic, rheumatologic ulcers and lesions in spinal cord injury patients. Based on these preliminary results, this study was developed to assess the effectiveness of blue light therapy in second and third stage pressure ulcers.</div></div><div><h3>Materials and methods</h3><div>This study was a randomized controlled trial enrolling hospitalized patients with poor mobility. The intervention group included blue light treatment in addition to standard care, three times a week, for 4 consecutive weeks. The primary objective is the difference in the healing process by measuring the average difference of the lesion's PUSH score between the first and the last visit.</div></div><div><h3>Results</h3><div>The analysis shows that the mean PUSH reduction and the probability of belonging to responder patients were higher in the treatment group. A latent profile analysis that identifies two trajectory classes based on treatment response, shows an association in the probability of following best trajectory for the treatment group (30 % vs 2 %).</div></div><div><h3>Conclusions</h3><div>The result shows that blue light photobiomodulation promotes recovery of tissue repair in pressure ulcers, and in stabilizing wounds that would otherwise worsen despite standard of care treatment. This therapy may be a valuable contribution to the daily management of pressure lesions since it has an excellent safety profile and the addition of this therapy to a treatment program may speed healing, improving the quality of life.</div><div>(<span><span>Clinicaltrials.gov</span><svg><path></path></svg></span> Ref. numb.: NCT05130814)</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 3","pages":"Article 100895"},"PeriodicalIF":2.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143724887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the structural and histopathological challenges of binary electrospun PET-based nanofibers for tissue engineering applications","authors":"Afsaneh Jahani ,&nbsp;Davod Mohebbi-Kalhori ,&nbsp;Farkhonde Sarhaddi ,&nbsp;Gholam Hosein Kazemzadeh ,&nbsp;Reza Taheri ,&nbsp;Mehdi Ahmadi ,&nbsp;Nafiseh Jirofti","doi":"10.1016/j.jtv.2025.100888","DOIUrl":"10.1016/j.jtv.2025.100888","url":null,"abstract":"<div><div>Tissue engineering and regenerative medicine aim to address tissue lesions and organ degenerations, enhancing clinical outcomes by restoring damaged tissues and functionalities. Recent progress in materials science and medicine has led to the development of regenerative engineering, revolutionizing the production of polymeric artificial scaffolds by electrospinning method, which mimic the extracellular matrix (ECM). Polyurethane (PU) is recognized for its elastic nature, comprising soft and hard segments, and possesses bioactive as well as biocompatible properties. Polycaprolactone (PCL), on the other hand, is a non-toxic polymer with a viscous nature, known for its favorable mechanical properties. This study focuses on the comprehensive histological evaluation of binary electrospun PET-based nanofiber scaffolds, as widely used in tissue engineering. The structural analysis involved FE-SEM imaging, porosity measurement, FTIR, and DSC examinations. In vitro assessments included degradation rates, water uptake, cell viability, morphological cell examination, and cell attachment studies. Additionally, scaffolds were subcutaneously implanted in rats for pathological examination. After a 30 days implantation period, histological and pathological parameters such as edema, inflammation, foreign body giant cell reaction, fibrosis, necrosis, and calcification were evaluated. The results highlight the successful application of blend electrospinning in producing PET/PCL and PET/PU nanofiber scaffolds with various composition ratios. FE-SEM imaging revealed uniform nanostructures without bead formation. Histological analysis showed favorable biocompatibility, with the PET/PCL (25:75) composition demonstrating superior structural characteristics compared to other ratios. The cell studies indicated that PET-based nanofiber scaffolds exhibited suitable cell viability and attachment, underscoring their potential for tissue engineering applications.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 3","pages":"Article 100888"},"PeriodicalIF":2.4,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143715552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Machine learning methods for determining skin age: A systematic review","authors":"Eric McMullen ,&nbsp;Rokhshid Aflaki ,&nbsp;Pranav Jignesh Khatri ,&nbsp;Dea Metko ,&nbsp;Kyle Storm ,&nbsp;Abu Bakar Butt ,&nbsp;Mahan Maazi ,&nbsp;Raghav Gupta ,&nbsp;Rajan Grewal ,&nbsp;Trevor Champagne","doi":"10.1016/j.jtv.2025.100887","DOIUrl":"10.1016/j.jtv.2025.100887","url":null,"abstract":"<div><h3>Aim</h3><div>This systematic review explores how machine learning is used in determining skin aging, aiming to evaluate accuracy, limitations, and gaps in the current literature.</div></div><div><h3>Materials and methods</h3><div>OVID Embase, OVID Medline, IEEE Xplore, and ACM Digitial Library were searched from inception to March 16, 2024.</div></div><div><h3>Results</h3><div>A total of 1467 non-duplicate articles were screened, and 27 were ultimately included in the systematic review. The machine learning models exhibited a range of accuracies from a mean absolute error of 2.30–8.16 years. The most common approach was full facial image analysis, followed by non-image-based studies utilizing biomarkers such as the methylome and the proteome. The incorporation of dynamic facial expressions in the analysis was shown to improve the accuracy of age estimation, with a mean absolute error of 3.74. Confocal microscopy demonstrated potential for accurate skin aging estimation, with some studies achieving up to 85 % accuracy. Many studies were found with high PROBAST risk of bias scores, most commonly due to small sample sizes.</div></div><div><h3>Conclusion</h3><div>Future studies should aim for greater diversity in ethnicity and variables within datasets to improve generalizability.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 3","pages":"Article 100887"},"PeriodicalIF":2.4,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143748702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of plant and animal-based interventions in preventing and reducing pressure injuries: A systematic review and meta-analysis","authors":"Esra Özkan ,&nbsp;Burçak Şahin Köze ,&nbsp;Meryem Yavuz van Giersbergen","doi":"10.1016/j.jtv.2025.100893","DOIUrl":"10.1016/j.jtv.2025.100893","url":null,"abstract":"<div><h3>Background</h3><div>Pressure injuries (PIs) are a significant concern among the elderly and bedridden patients, often resulting from prolonged pressure on the skin. Various interventions, including plant and animal-based therapies, are used to prevent and treat PIs. However, there is a lack of comprehensive understanding of the effectiveness of these natural interventions.</div></div><div><h3>Aim</h3><div>This study aims to systematically review and conduct a meta-analysis of studies using plant and animal-based interventions to prevent and treat pressure injuries.</div></div><div><h3>Methods</h3><div>A systematic review and meta-analysis were performed according to the PRISMA guidelines. Searches were conducted in PubMed, Web of Science, SCOPUS, and Cochrane databases using keywords related to pressure injuries and natural interventions. Studies published between 2003 and 2023 were included. The inclusion criteria were experimental, quasi-experimental, and case-control studies. Data extraction and quality assessment were performed independently by two researchers. The effect size was calculated using Hedges' g, and heterogeneity was assessed using Cochrane Q and I² tests.</div></div><div><h3>Results</h3><div>A total of 13,563 records were identified, with 20 studies meeting the inclusion criteria after screening and full-text review. The total sample size was 2541 participants. The meta-analysis revealed a significant overall effect size (g = −0.614, 95 % CI: −0.890 to −0.337) indicating moderate effectiveness of plant and animal-based interventions in preventing and reducing PIs. Aloe vera, olive oil, and fish oil showed significant effects with p-values &lt;0.05. High heterogeneity was observed among the studies (Q = 91.007, p &lt; 0.05; I² = 79.123 %), leading to the use of a random effects model.</div></div><div><h3>Conclusions</h3><div>Plant and animal-based interventions are moderately effective in preventing and reducing pressure injuries. These findings support the integration of natural therapies into clinical practice for PI management. Further research is needed to standardize protocols and explore the long-term effects of these interventions.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 3","pages":"Article 100893"},"PeriodicalIF":2.4,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143715553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesising the evidence for patient and public involvement in pressure ulcer research: A scoping review protocol","authors":"Hannah Wilson ,&nbsp;Aglecia Moda Vitoriano Budri ,&nbsp;Liane Araujo Teixeira ,&nbsp;Pinar Avsar ,&nbsp;Linda Nugent ,&nbsp;Niamh Dillon ,&nbsp;Declan Naughton ,&nbsp;Wendy Chaboyer ,&nbsp;Tom O'Connor ,&nbsp;Killian Walsh ,&nbsp;Sharon Latimer ,&nbsp;Zena Moore","doi":"10.1016/j.jtv.2025.100892","DOIUrl":"10.1016/j.jtv.2025.100892","url":null,"abstract":"<div><h3>Introduction</h3><div>There is a growing shift toward greater inclusion of patients and the public in the design, conduct, and implementation of research to ensure it is more meaningful, relevant and impactful. This involvement creates a partnership in which patients and the public contribute to decisions throughout the research lifecycle. While the impact and importance of patient and public involvement (PPI) in research is becoming increasingly recognised, the extent of PPI in pressure ulcer (PU) research has yet to be fully established. This scoping review aims to provide insights into how PPI has been included and reported in PU research, ultimately placing a spotlight on the impact and importance of reporting PPI to guide future PU research.</div></div><div><h3>Methods and analysis</h3><div>Through synthesising literature from a diverse global landscape, this scoping review aims to achieve the following objectives (1) To explore and map the stage(s) of the PU research cycle where PPI has been incorporated (2) To identify and describe the range of participatory methods, including frameworks, guidelines, or tools, that have been used to facilitate the involvement of patients and the public in PU research. (3) To identify and synthesise reporting impacts of including PPI in PU research, and (4) To map and analyse the terminology commonly used to describe PPI in PU research.</div><div>The Joanna Briggs Institute scoping review methodology and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping reviews framework will guide the conduct and reporting of this review. Nine databases will be included in the search strategy and all articles will be independently screened for eligibility by two authors. Data from eligible articles will be extracted using a pre-defined data extraction table, and the results will be analysed and synthesised using the PAGER (Patterns, Advances, Gaps, Evidence for practice and Research recommendations) framework.</div></div><div><h3>Ethics and dissemination</h3><div>Ethics approval will not be required considering the nature of this scoping review. PPI advisory partners will be consulted for disseminating the results in a format that is accessible and understood by a layperson, in order to communicate the findings to a wide audience and diverse communities. This scoping review will be published in a peer reviewed journal and results will be disseminated at local national and international conferences.</div></div><div><h3>Registration</h3><div>This scoping review is registered on the Open Science Framework (<span><span>https://doi.org/10.17605/OSF.IO/JHT34</span><svg><path></path></svg></span>). As is typical with scoping reviews, this protocol may evolve over time. Any updates will be documented on the Open Science Framework platform, along with a clear rationale for the changes.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100892"},"PeriodicalIF":2.4,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143706508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bridging the gap: ICU nurses’ experiences in detecting pressure injuries across diverse skin tones","authors":"Herminigildo II Lo ,&nbsp;Eleanor Hollywood ,&nbsp;Rosemarie Derwin","doi":"10.1016/j.jtv.2025.100891","DOIUrl":"10.1016/j.jtv.2025.100891","url":null,"abstract":"<div><h3>Background</h3><div>Pressure Injury detection remains a challenge in patients with darker skin tones due to the absence of visible erythema, resulting in delayed diagnosis and poorer patient outcomes. Despite international guidelines, nurses face barriers in early recognition due to knowledge gaps and inadequate training in skin tone diversity. A timely assessment is critical for effective treatment. This necessitates that healthcare professionals recognise how early pressure ulcer signs may present in patients of all skin tone types.</div></div><div><h3>Aim</h3><div>To explore ICU nurses’ experiences in assessing pressure areas in patients with dark skin tones and identify challenges and solutions.</div></div><div><h3>Methodology</h3><div>Following ethical approval, semi-structured interviews were conducted with 11 ICU Nurses. Interview data were analysed using thematic analysis using NVivo software.</div></div><div><h3>Findings</h3><div>Three key themes emerged: (1) Gaps in education and training on diverse skin tones, (2) Challenges in early detection due to “white normativity” in assessment tools, and (3) The need for inclusive education and advanced diagnostic tools to mitigate disparities.</div></div><div><h3>Conclusion</h3><div>Urgent improvements in nursing curricula and clinical training are required to ensure equitable pressure injury detection for all skin tones. The study advocates for greater inclusivity in educational materials, continuous professional development, and the integration of advanced tools like infrared thermography and subepidermal moisture scanners.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 3","pages":"Article 100891"},"PeriodicalIF":2.4,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143768940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new conceptual model for how pressure ulcer risk is negotiated and adherence to preventative advice in the community setting","authors":"Lisa Ledger ,&nbsp;Jo Hope ,&nbsp;Lisette Schoonhoven ,&nbsp;Peter R. Worsley","doi":"10.1016/j.jtv.2025.100890","DOIUrl":"10.1016/j.jtv.2025.100890","url":null,"abstract":"<div><h3>Aim(s)</h3><div>To identify potential factors affecting patient adherence to preventative advice and to explore how pressure ulcer risk is negotiated between nurse and patient in the community setting.</div></div><div><h3>Design</h3><div>A qualitative research design using a pragmatist approach.</div></div><div><h3>Methods</h3><div>Observation of interactions between nurse and patient, evaluation of documentation, and semi-structured interviews with 15 community patients following the nursing interaction. Data was analysed using the principles of Thematic Analysis.</div></div><div><h3>Results</h3><div>Five overarching themes affected patient adherence to pressure ulcer preventative advice: Patient decision-making, difficulty implementing advice, carer involvement, trust in the nurse and the nursing approach. These factors were complex, individualised, dynamic, and context and time specific. How pressure ulcer avoidance was negotiated diverged according to the type of nursing approach adopted, which impacted on adherence.</div></div><div><h3>Conclusion</h3><div>The new conceptual model identifies the importance of an open, participatory nursing approach to support shared decision-making. It accommodates the dynamic nature of patient factors, which affect their ability to acquire and understand PU advice and adhere to preventative strategies.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100890"},"PeriodicalIF":2.4,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143679729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding recurrent pressure injuries: A scoping review of current research and risk factors","authors":"Li Du ,&nbsp;Ning Wang ,&nbsp;Juhong Pei ,&nbsp;Yanxia Jiao ,&nbsp;Jie Xu ,&nbsp;Xinyue Xu ,&nbsp;Anna Wen ,&nbsp;Lin Han ,&nbsp;Lin Lv","doi":"10.1016/j.jtv.2025.100886","DOIUrl":"10.1016/j.jtv.2025.100886","url":null,"abstract":"<div><h3>Aim</h3><div>To describe published studies on the current status of recurrent pressure injuries.</div></div><div><h3>Background</h3><div>Pressure injuries burden patients and the health care system, so it is essential to prevent their recurrence and prevent patients from experiencing secondary injury. However, most current studies focus on primary pressure injury and less on its recurrence.</div></div><div><h3>Design and methods</h3><div>We employed a scoping review methodology. From the database construction until December 9, 2024, we searched PubMed, Embase, Web of Science, CINAHL, and the Cochrane Library. Two researchers independently screened and extracted data.</div></div><div><h3>Results</h3><div>Twenty-eight articles met our criteria, most published after 2000. The included studies showed that 13 articles dealt with the definition of recurrent pressure injuries, but no uniform standard has been formed yet. The incidence of recurrent pressure injuries is 5.4 %–73.6 %. The most commonly reported site of recurrence is the ischium. The high-risk population for recurrence is the patient with spinal cord injury. Eleven studies described 26 risk factors for recurrent pressure injuries, of which albumin was the most commonly reported risk factor, followed by spinal cord injuries, age, hospital stay, and ulcer size. The 26 risk factors were summarised into five aspects: personal factors, social-environmental factors, disease-related factors, physiological and biochemical parameters, and Initial ulcer characteristics.</div></div><div><h3>Conclusions</h3><div>The incidence of recurrent pressure injuries varies widely, and specific definitions and standardised staging criteria must be further determined to improve clinical judgment and reporting accuracy. The risk factors for recurrent pressure injuries involve many aspects. Some studies have described local flaps and overall recurrence risk factors separately, and further verification is needed to determine whether there is a difference between the two.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100886"},"PeriodicalIF":2.4,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143643905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diabetic foot care behavior and self-efficacy levels in individuals with diabetic foot ulcers in Turkey","authors":"Emine Sezgunsay ,&nbsp;Murat Urkan ,&nbsp;Mustafa Deveci","doi":"10.1016/j.jtv.2025.100885","DOIUrl":"10.1016/j.jtv.2025.100885","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to explore the connection between demographic characteristics, diabetes-related knowledge, foot self-care behaviors, and self-efficacy levels in individuals with diabetic foot ulcers. Additionally, it investigated whether there is a correlation between foot care behaviors and self-efficacy levels among these individuals.</div></div><div><h3>Methods</h3><div>This descriptive and cross-sectional study was conducted with individuals who applied to a training and research hospital with a diabetic foot ulcer and received treatment between October 2019 and October 2020. Data were collected through the Patient Identification Characteristics Form, the Diabetes Management Self-Efficacy Scale, and the Foot Self-Care Behavior Scale. Percentage, mean, Mann-Whitney <em>U</em> test, Kruskal-Wallis test, and Spearman correlation analysis were used to analyze the data.</div></div><div><h3>Results</h3><div>The mean self-efficacy score among individuals with diabetic foot ulcers was 68.39 ± 14.03, while the mean foot self-care behavior score was 59.10 ± 10.13. Previous diabetes education, regular exercise, and educational status significantly influenced scores on both scales. Furthermore, a positive linear relationship was observed between foot self-care behaviors and self-efficacy levels in individuals with diabetic foot.</div></div><div><h3>Conclusions</h3><div>To enhance self-efficacy levels and promote foot self-care behaviors in individuals with diabetic foot ulcers, continuous education, and regular follow-up examinations are essential. Providing tailored care based on demographic characteristics and evolving health conditions related to diabetes is expected to reduce complications effectively.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100885"},"PeriodicalIF":2.4,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143642385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence rate and risk factors of intraoperative-acquired pressure injury in posterior interbody fusion: A retrospective study of a national inpatient sample database","authors":"Xuelian Wang ,&nbsp;Mengmeng Shao ,&nbsp;Jian Wang ,&nbsp;Xiaoshuang Liang ,&nbsp;Yuhang Chen ,&nbsp;Haofei Wang ,&nbsp;Jianlong Li","doi":"10.1016/j.jtv.2025.100873","DOIUrl":"10.1016/j.jtv.2025.100873","url":null,"abstract":"<div><h3>Background</h3><div>Intraoperative-acquired pressure injuries (IAPIs) are a common complication in posterior intervertebral fusion surgery, leading to adverse outcomes for patients. However, there is a lack of large-scale national database research analyzing the morbidity and associated risk factors of IAPIs in this surgical procedure.</div></div><div><h3>Methods</h3><div>This retrospective study analyzed data from the National Inpatient Sample (NIS) database from 2010 to 2019. Demographic, hospital, and patient characteristics were examined, including length of stay (LOS), total costs, in-hospital mortality, preoperative comorbidities, and complications.</div></div><div><h3>Result</h3><div>The overall incidence of IAPIs in posterior intervertebral fusion surgery was 0.2 % from 2010 to 2019. The annual occurrence of interbody fusion demonstrated an M-shaped trend, with rates of 0.2 % in 2010, 0.05 % in 2016, and 0.05 % in 2019. IAPIs were associated with increased preoperative complications, longer LOS, higher total hospitalization costs, and higher in-hospital mortality rates. Risk factors for IAPIs included comorbidities, large hospitals, urban hospitals, deficiency anemia, coagulation disorders, fluid electrolyte disorders, paralysis, and weight loss. Additionally, IAPIs were linked to medical complications such as sepsis, deep vein thrombosis, urinary tract infections, acute renal failure, shock, pneumonia, blood transfusion, and surgical complications such as cerebrospinal fluid leak. Elective admission was found to be a protective factor.</div></div><div><h3>Conclusion</h3><div>Identifying risk factors for IAPIs in posterior intervertebral fusion surgery can help identify high-risk patients and develop preventive measures. By targeting these risk factors, the incidence of IAPIs can be reduced, leading to improved patient outcomes.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100873"},"PeriodicalIF":2.4,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143636810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}