银敷料治疗糖尿病足溃疡：系统回顾和荟萃分析。

IF 2.4 3区医学 Q2 DERMATOLOGY

Journal of tissue viability Pub Date : 2025-09-22 DOI:10.1016/j.jtv.2025.100956

Qinci Xie , Jinying Wang , Gaofeng Huang , Jiezhi Dai

{"title":"银敷料治疗糖尿病足溃疡：系统回顾和荟萃分析。","authors":"Qinci Xie , Jinying Wang , Gaofeng Huang , Jiezhi Dai","doi":"10.1016/j.jtv.2025.100956","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>We performed this meta-analysis to evaluate the effects of effectiveness of silver-based dressings for the treatment of diabetic foot ulcer (DFU).</div></div><div><h3>Methods</h3><div>In the study, we searched electronic databases including PubMed, EMBASE, BIOSIS, Web of Science, Cochrane Central Register of Controlled Trials (CENTRAL), and Google Scholar internet. The study was carried out from inception to Sep 30, 2024, with English-language papers only being considered. We assessed eligible studies that comparing the effects of silver dressings with other dressings on wound healing in DFU. The primary outcomes included complete ulcer healing rate and healing time. The standard mean differences (SMDs) or the odds ratios (ORs) was calculated for continuous or dichotomous data, respectively.</div></div><div><h3>Results</h3><div>In our study, twelve trials with 808 patients and 857 ulcers were included. The meta-analysis showed a high ulcer healing rate in the silver dressing group compared with the control group (OR = 1.92, 95 % CI 1.36 to 2.72, P = 0.06), and the ulcer healing time in the silver dressing group was significantly shorter than that in the control group (SMD = -2.08, 95 % CI -2.92 to −1.25 P < 0.00001, I<sup>2</sup> = 91 %).</div></div><div><h3>Conclusion</h3><div>silver dressing is effective in enhancing complete healing rate and shortening ulcer healing time in DFU, suggesting its potential as a superior adjunct in treatment of DFU. More high-quality and well-designed research is required in the future.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 4","pages":"Article 100956"},"PeriodicalIF":2.4000,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Silver dressings for treating diabetic foot ulcers: a systematic review and meta-analysis\",\"authors\":\"Qinci Xie , Jinying Wang , Gaofeng Huang , Jiezhi Dai\",\"doi\":\"10.1016/j.jtv.2025.100956\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>We performed this meta-analysis to evaluate the effects of effectiveness of silver-based dressings for the treatment of diabetic foot ulcer (DFU).</div></div><div><h3>Methods</h3><div>In the study, we searched electronic databases including PubMed, EMBASE, BIOSIS, Web of Science, Cochrane Central Register of Controlled Trials (CENTRAL), and Google Scholar internet. The study was carried out from inception to Sep 30, 2024, with English-language papers only being considered. We assessed eligible studies that comparing the effects of silver dressings with other dressings on wound healing in DFU. The primary outcomes included complete ulcer healing rate and healing time. The standard mean differences (SMDs) or the odds ratios (ORs) was calculated for continuous or dichotomous data, respectively.</div></div><div><h3>Results</h3><div>In our study, twelve trials with 808 patients and 857 ulcers were included. The meta-analysis showed a high ulcer healing rate in the silver dressing group compared with the control group (OR = 1.92, 95 % CI 1.36 to 2.72, P = 0.06), and the ulcer healing time in the silver dressing group was significantly shorter than that in the control group (SMD = -2.08, 95 % CI -2.92 to −1.25 P < 0.00001, I<sup>2</sup> = 91 %).</div></div><div><h3>Conclusion</h3><div>silver dressing is effective in enhancing complete healing rate and shortening ulcer healing time in DFU, suggesting its potential as a superior adjunct in treatment of DFU. More high-quality and well-designed research is required in the future.</div></div>\",\"PeriodicalId\":17392,\"journal\":{\"name\":\"Journal of tissue viability\",\"volume\":\"34 4\",\"pages\":\"Article 100956\"},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2025-09-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of tissue viability\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0965206X25001044\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of tissue viability","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0965206X25001044","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"DERMATOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

背景：我们进行了这项荟萃分析，以评估银基敷料治疗糖尿病足溃疡（DFU）的有效性。方法：检索PubMed、EMBASE、BIOSIS、Web of Science、Cochrane Central Register of Controlled Trials （Central）、谷歌Scholar internet等电子数据库。这项研究从开始进行到2024年9月30日，只考虑英语论文。我们评估了比较银敷料与其他敷料对DFU伤口愈合影响的合格研究。主要结局包括溃疡完全愈合率和愈合时间。分别计算连续数据和二分类数据的标准均差（SMDs）和比值比（ORs）。结果：在我们的研究中，纳入了12项试验，涉及808例患者和857例溃疡。荟萃分析显示，银敷料组溃疡愈合率高于对照组（OR = 1.92, 95% CI 1.36 ~ 2.72, P = 0.06），银敷料组溃疡愈合时间显著短于对照组（SMD = -2.08, 95% CI -2.92 ~ -1.25, P = 91%）。结论：银敷料能有效提高DFU的完全愈合率，缩短溃疡愈合时间，是治疗DFU的一种较好的辅助治疗手段。未来需要更多高质量和精心设计的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Silver dressings for treating diabetic foot ulcers: a systematic review and meta-analysis

Background

We performed this meta-analysis to evaluate the effects of effectiveness of silver-based dressings for the treatment of diabetic foot ulcer (DFU).

Methods

In the study, we searched electronic databases including PubMed, EMBASE, BIOSIS, Web of Science, Cochrane Central Register of Controlled Trials (CENTRAL), and Google Scholar internet. The study was carried out from inception to Sep 30, 2024, with English-language papers only being considered. We assessed eligible studies that comparing the effects of silver dressings with other dressings on wound healing in DFU. The primary outcomes included complete ulcer healing rate and healing time. The standard mean differences (SMDs) or the odds ratios (ORs) was calculated for continuous or dichotomous data, respectively.

Results

In our study, twelve trials with 808 patients and 857 ulcers were included. The meta-analysis showed a high ulcer healing rate in the silver dressing group compared with the control group (OR = 1.92, 95 % CI 1.36 to 2.72, P = 0.06), and the ulcer healing time in the silver dressing group was significantly shorter than that in the control group (SMD = -2.08, 95 % CI -2.92 to −1.25 P < 0.00001, I² = 91 %).

Conclusion

silver dressing is effective in enhancing complete healing rate and shortening ulcer healing time in DFU, suggesting its potential as a superior adjunct in treatment of DFU. More high-quality and well-designed research is required in the future.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Journal of tissue viability DERMATOLOGY-NURSING

CiteScore

3.80

自引率

16.00%

发文量

110

审稿时长

>12 weeks

期刊介绍： The Journal of Tissue Viability is the official publication of the Tissue Viability Society and is a quarterly journal concerned with all aspects of the occurrence and treatment of wounds, ulcers and pressure sores including patient care, pain, nutrition, wound healing, research, prevention, mobility, social problems and management. The Journal particularly encourages papers covering skin and skin wounds but will consider articles that discuss injury in any tissue. Articles that stress the multi-professional nature of tissue viability are especially welcome. We seek to encourage new authors as well as well-established contributors to the field - one aim of the journal is to enable all participants in tissue viability to share information with colleagues.