Journal of studies on alcohol and drugs最新文献

{"title":"Association of Anticipated Stimulant and Sedative Effects of Alcohol With Future Heavy Drinking in a Large Swiss Cohort Study of Young Men.","authors":"Gerhard Gmel, Tommaso Comodo, Joseph Studer, Andrea C King","doi":"10.15288/jsad.25-00189","DOIUrl":"10.15288/jsad.25-00189","url":null,"abstract":"<p><strong>Objective: </strong>Theories posit that acute alcohol responses predict the development of future heavy alcohol use and alcohol-related problems. The most prominent of these theories is the low-level response theory, which purports that less intense alcohol responses are associated with later development of alcohol use disorder. The counter-modified differentiator model posits that greater stimulant effects with lower sedative effects predict future heavy drinking. The present study provided a concurrent testing of these theories in a large-scale cohort of young adult Swiss men.</p><p><strong>Method: </strong>Data were derived from two waves of the Cohort Study on Substance Use Risk Factors in 2,749 French-speaking, current alcohol-consuming young adult men age 25.7 years at baseline and 28.5 years at follow-up. Participants completed the 6-item Anticipated Brief Biphasic Alcohol Effects Scale with the instructions of the anticipated effects they feel after consuming five standard drinks, and the stimulation and sedation subscales were used in analyses. Associations of these scores with volume of drinking and frequency of heavy episodic drinking were determined both at baseline and at 3-year follow-up. Models were adjusted for covariates, including disinhibited personality and family history of alcohol problems.</p><p><strong>Results: </strong>Results show that anticipated stimulation effects of alcohol predicted increasing alcohol consumption over time, and anticipated sedative alcohol effects predicted reductions in consumption (<i>p</i> values ≤ .001).</p><p><strong>Conclusions: </strong>The present study supported the modified differentiator model in that higher anticipated stimulation and lower sedation predicted future alcohol consumption patterns. This may be useful for preventing heavy drinking and informing pharmacological interventions intended to reduce the pleasurable effects.</p>","PeriodicalId":17159,"journal":{"name":"Journal of studies on alcohol and drugs","volume":" ","pages":"565-573"},"PeriodicalIF":2.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145540584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New Alcohol Warnings Outperform the Current U.S. Warning in a National Survey Experiment.","authors":"Anna H Grummon, Cristina J Y Lee, Aline D'Angelo Campos, Allison J Lazard, Noel T Brewer, Callie Whitesell, Phoebe R Ruggles, Thomas K Greenfield, Marissa G Hall","doi":"10.15288/jsad.25-00226","DOIUrl":"10.15288/jsad.25-00226","url":null,"abstract":"<p><strong>Objective: </strong>The purpose of this study was to identify which topics for alcohol warnings most motivate people to reduce their drinking and best inform them of alcohol's harms.</p><p><strong>Method: </strong>A nationally representative sample of U.S. adults (<i>n</i> = 1,036) aged 21 years and older who drink alcohol completed an online survey in September-October 2024. Participants viewed 10 messages (one control and nine warnings) in random order. The nine warning messages were the current U.S. warning plus eight new warning topics (e.g., colorectal cancer, dementia). Participants rated each message on the extent to which it encouraged them to drink less alcohol (perceived message effectiveness, 1-5 scale, primary outcome), the extent to which it reminded them of the harms of alcohol consumption (1-5 scale), and whether they learned something new.</p><p><strong>Results: </strong>Compared with the control, all nine warning topics were perceived as more effective (range of predicted means: 1.93-2.66 for warnings vs. 1.35 for control, <i>p</i>s < .001), better reminded participants of alcohol's harms (range of predicted means: 2.33-3.15 for warnings vs. 1.40 for control, <i>p</i>s < .001), and were more likely to help participants learn something new (range of predicted probabilities: 18%-54% for warnings vs. 14% for control, <i>p</i>s < .05). All new warning topics except for drinking guidelines were perceived as more effective than the current U.S. warning (<i>p</i>s < .001). Among new warning topics, cancer, dementia, liver disease, and hypertension showed the most promise.</p><p><strong>Conclusions: </strong>New alcohol warnings are a promising strategy for informing people and encouraging them to drink less, especially warnings focused on cancer, dementia, liver disease, or hypertension.</p>","PeriodicalId":17159,"journal":{"name":"Journal of studies on alcohol and drugs","volume":" ","pages":"433-443"},"PeriodicalIF":2.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12574658/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145113540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developmental Differences Emerge in How Negative Consequences, Negative Expectancies, and Alcohol Use Relate Over Time.","authors":"Bernard Pereda, Craig R Colder","doi":"10.15288/jsad.25-00221","DOIUrl":"10.15288/jsad.25-00221","url":null,"abstract":"<p><strong>Objective: </strong>Learning theories suggest an aversive learning process whereby negative consequences of alcohol use curtail drinking. However, the literature examining this prospective association is mixed. We aimed to clarify this aversive learning process by identifying how (mediators), for whom (moderators), and when (differences across development) such learning occurs. Negative alcohol expectancies were proposed as a mediator, and sensitivity to punishment was proposed as a moderator. Negative consequences were hypothesized to lead to increases in negative expectancies and, in turn, reductions in alcohol use. Associations were expected to be strongest among those with high sensitivity to punishment. This proposed aversive learning pathway was estimated in adolescence (limited alcohol experience) and young adulthood (significant alcohol experience) to examine differences in learning across the developmental period.</p><p><strong>Method: </strong>Data from a longitudinal community sample (<i>N</i> = 387) were analyzed using prospective path models, with annual assessments conducted over 3 years in adolescence (ages 12-14) and young adulthood (ages 19-21).</p><p><strong>Results: </strong>In adolescence, negative consequences were not associated with negative expectancies, but negative expectancies were inversely associated with alcohol use. In contrast, negative consequences were positively associated with negative expectancies in young adulthood, but negative expectancies were not associated with alcohol use. Moderation was not supported.</p><p><strong>Conclusions: </strong>Negative consequences are uncommon among community adolescents and, as a result, may not shape negative expectancies, yet negative expectancies are protective against alcohol use. In young adulthood, negative consequences appear salient enough to shape negative expectancies, but they no longer serve a protective function. Findings suggest a shifting role of drinking experience in the development of expectancies and the influence of expectancies on alcohol use.</p>","PeriodicalId":17159,"journal":{"name":"Journal of studies on alcohol and drugs","volume":" ","pages":"555-564"},"PeriodicalIF":2.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12767266/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145756985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"More Than Half of Retailers Sold Hemp-Derived THC Products to Underage-Appearing Buyers Despite Age Restrictions.","authors":"Eileen Delehanty, Darin J Erickson, Marizen Ramirez, M Kumi Smith, Traci L Toomey","doi":"10.15288/jsad.25-00393","DOIUrl":"https://doi.org/10.15288/jsad.25-00393","url":null,"abstract":"<p><strong>Objective: </strong>The 2018 Federal Farm Bill created a loophole allowing intoxicating hemp-derived tetrahydrocannabinol (THC) products to be manufactured and sold with limited regulations. Unless restricted by the state, these products are available across many retailer types. We assessed the likelihood of sales of hemp-derived THC products to underage individuals in one large city in Minnesota, USA which had a minimum purchase age of 21 but few other restrictions.</p><p><strong>Method: </strong>We conducted pseudo-underage purchase attempts at establishments that reported or were observed carrying hemp-derived THC products in 2023. Buyers, 21 or older but judged by a panel to look aged 18-20, attempted to purchase hemp-derived THC products without age identification. We assessed whether the availability and purchase rate differed by community economic advantage and establishment type.</p><p><strong>Results: </strong>Approximately one-third (149/452) of establishments carried hemp-derived THC products. The overall pseudo-underage sales rate was 56% (70/125). Establishments in areas of higher (vs. lower) economic advantage were more likely to carry hemp-derived THC products (40% vs. 30%) but less likely to sell to a pseudo-underage individual (49% vs. 68%). Compared to establishments that primarily sell non-age-restricted items (e.g., gas stations, grocery stores), establishments that primarily sell age-restricted products (liquor stores, tobacco stores, hemp-dispensaries) were more likely to carry these products (69% vs. 20%) but equally as likely to sell to pseudo-underage individuals (54% vs. 57%).</p><p><strong>Conclusions: </strong>Our results suggest that underage people could easily access hemp-derived THC products. It is imperative that these products are considered in assessments on availability of cannabis.</p>","PeriodicalId":17159,"journal":{"name":"Journal of studies on alcohol and drugs","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147774830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alcohol Shifts Emotional Language in Social Interaction Toward Positive and Away from Negative Content: A Language-Processing Analysis.","authors":"Madeline E Goodwin, Michael A Sayette","doi":"10.15288/jsad.25-00385","DOIUrl":"https://doi.org/10.15288/jsad.25-00385","url":null,"abstract":"<p><strong>Objective: </strong>Although alcohol is largely consumed socially, experiments rarely test its effects on social language. Guided by the premise that language is a fundamental social behavior that shapes alcohol's socio-emotional effects, this preregistered study addresses critical gaps by testing alcohol's verbal effects in unstructured small-group interactions using the largest sample to date, proper controls, and reliable/replicable text-processing measures.</p><p><strong>Method: </strong>Sayette et al. (2012) randomly assigned unacquainted triads of social drinkers (360 males, 360 females) to alcohol, placebo, or control conditions, and recorded them during an unstructured interaction. Here, extensive transcription efforts permitted examination of alcohol's impact on approximately half-a-million words, using the Linguistic Inquiry and Word Count (LIWC) system.</p><p><strong>Results: </strong>Hypotheses aligned with general verbal disinhibition were unsupported. Instead, alcohol, vs. placebo and control, decreased the proportion of negative emotion words (<i>B</i> = -0.19, <i>OR</i> = 0.83, p < .001) and increased occurrence of positive-emotion words (<i>B</i>=0.26, <i>IRR</i> = 1.30, <i>p</i> = .002). Further, there was a trend such that alcohol, vs. placebo and control, reduced verbal authenticity (<i>B</i> = -4.32, β = -0.19, <i>SE</i> = 2.37, <i>t</i>(233.23) = -1.82, <i>p</i> = .07). Post-hoc analyses suggested this effect was driven by males, with alcohol decreasing authenticity (<i>B</i> = -9.85, β = -0.43, <i>p</i> = .040) and increasing confident/dominant language (<i>B</i> = 9.63, β = 0.42, <i>p</i> = .045), selectively in all-male groups.</p><p><strong>Conclusions: </strong>Results indicate that alcohol alters the emotional focus of conversation and illuminate potential sex-differences in its effects on authenticity/bravado. This study underscores the value of incorporating formal language measures into alcohol (and other drug) research.</p>","PeriodicalId":17159,"journal":{"name":"Journal of studies on alcohol and drugs","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147774777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pressure to Acculturate Amplifies Coping-Depression Associations With Alcohol Consequences in Hispanic/Latino College Students.","authors":"Jessica M Cavalli, Amie R Newins, Byron L Zamboanga, Kathryne Van Hedger, Katherine Walukevich-Dienst, Alan Meca, Su Yeong Kim","doi":"10.15288/jsad.25-00260","DOIUrl":"https://doi.org/10.15288/jsad.25-00260","url":null,"abstract":"<p><strong>Background: </strong>Hispanic/Latino American college students report elevated rates of alcohol use and negative alcohol-related consequences compared to non-Hispanic/Latino white students. As cultural experiences and coping motives (i.e., drinking to manage negative emotions) can influence alcohol outcomes in Hispanic/Latino Americans, the current study examined how the interplay of acculturative stress and coping motives are related to alcohol use and negative alcohol-related consequences among Hispanic/Latino American college students.</p><p><strong>Method: </strong>A large, multisite sample of Hispanic/Latino American college students (<i>n</i>=1,131; ages 18-25) completed cross-sectional measures on acculturative stress, coping motives, alcohol use, and negative alcohol-related consequences. We estimated path models to examine the moderating effect of two domains of acculturative stress (i.e., pressure to acculturate and pressure against acculturation) on the associations between the two coping motives (i.e., drinking to cope with anxiety and depressive symptoms) and the alcohol outcomes, while adjusting for theoretically relevant covariates (i.e., age, gender, fraternity/sorority membership, athletic involvement, general college stress).</p><p><strong>Results: </strong>There was a significant interaction between coping-depression motives and pressure to acculturate, such that the positive relationship between the two was stronger among students experiencing higher levels of pressure to acculturate. No other significant interactions emerged. Additionally, both coping-anxiety and coping-depression motives showed significant, positive direct effects on negative alcohol-related consequences.</p><p><strong>Conclusions: </strong>The current study identified a specific domain of acculturative stress (pressure to acculturate) that intensifies the association between drinking to cope with depressive symptoms and more negative alcohol-related consequences among Hispanic/Latino American college students.</p>","PeriodicalId":17159,"journal":{"name":"Journal of studies on alcohol and drugs","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147774911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Exploratory Content Analysis of Alcohol-Related Posts on Social Media by Influencers in India: Implications for Public Health in Low and Middle-Income Countries.","authors":"Prashant Kumar Singh, Aditi Upadhyaya, Aashna Mehta, Yatan Pal Singh Balhara, Shalini Singh","doi":"10.15288/jsad.25-00372","DOIUrl":"https://doi.org/10.15288/jsad.25-00372","url":null,"abstract":"<p><strong>Objectives: </strong>Social media influencers significantly shape alcohol consumption norms, particularly in Low and Middle-Income Countries (LMICs) where regulatory frameworks lag behind digital marketing innovations. This study analyzed alcohol-related content posted by social media influencers in India.</p><p><strong>Methods: </strong>Thematic content analysis was conducted on 3,442 alcohol-related posts from 50 influencer accounts on Instagram and Facebook over 5 months (January-May 2025). A hybrid deductive-inductive approach identified underlying narratives and implicit meanings beyond surface-level coding.</p><p><strong>Results: </strong>Five major themes emerged: (1) Alcohol as Social Capital and Lifestyle Enhancement, (2) Cultural Integration and Normalization, (3) Aspirational Consumption and Peer Influence, (4) Commercial Disguise and Transparency Deficit, and (5) Gender-Specific Targeting and Regional Concentration. Foreign brands dominated content (65%), with whiskey most featured (32.0%). High engagement patterns (maximum: 487,251 likes) revealed strong audience resonance with lifestyle-aspirational content, while 86% of influencers failed to disclose commercial partnerships.</p><p><strong>Conclusions: </strong>Social media influencers construct sophisticated narratives positioning alcohol as integral to social success and aspirational lifestyles. These marketing strategies extend beyond product promotion to embed alcohol consumption within fundamental social needs, representing significant public health concerns in LMICs with underdeveloped digital regulatory frameworks.</p>","PeriodicalId":17159,"journal":{"name":"Journal of studies on alcohol and drugs","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147774846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cannabis Use Disorder and Suicidal Ideation in the United States: Persistent Risk and Stable Trends, 2014-2023.","authors":"Tosin Philip Oyetunji, Alec M Chan-Golston, Sandie Ha, Sidra Goldman-Mellor","doi":"10.15288/jsad.25-00481","DOIUrl":"https://doi.org/10.15288/jsad.25-00481","url":null,"abstract":"<p><strong>Objective: </strong>Amid rising cannabis use, declining perceived harm, and policy liberalization over the past 15 years, we examined whether the association between cannabis use disorder (CUD) and past-year suicidal ideation among U.S. adults changed from 2014-2023 and varied by sex, age, and race/ethnicity.</p><p><strong>Method: </strong>Using data from 415,861 adults in the 2014-2023 National Surveys on Drug Use and Health, we examined temporal association change between past-year suicidal ideation and CUD (≥2 of 9 harmonized DSM-5 criteria). Logistic regression models, adjusted for demographic, social, clinical, and geographic covariates, tested whether survey year moderated the CUD-suicidal ideation association overall and in strata by sex, age, and race/ethnicity.</p><p><strong>Results: </strong>Adults with cannabis use disorder had 57% higher odds of past-year suicidal ideation than those without (OR, 1.57; 95% CI, 1.44-1.72) across years. Joint Wald tests showed no evidence that the association changed over time overall (p = 0.12) nor within strata defined by sex or age. Although the joint interaction test suggested some variation among Hispanic respondents (p = 0.01), no individual year-specific interaction terms remained statistically significant after Bonferroni correction.</p><p><strong>Conclusions: </strong>Adults with CUD had higher odds of suicidal ideation but, contrary to expectations, the strength of this association remained stable from 2014-2023 and did not differ significantly across sex, age, or racial/ethnic groups despite widespread legalization, increased potency, and shifting norms.</p>","PeriodicalId":17159,"journal":{"name":"Journal of studies on alcohol and drugs","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147717179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Limited Evidence on Cannabis Taxation Effects in the United States: A Rapid Review of Use, Purchasing, and Risk Perceptions.","authors":"Melissa Ponce, Kara R Skelton","doi":"10.15288/jsad.25-00400","DOIUrl":"https://doi.org/10.15288/jsad.25-00400","url":null,"abstract":"<p><strong>Objective: </strong>The global cannabis policy landscape has changed dramatically in recent decades. In the United States, there is significant variation in cannabis tax structures, and there is limited consensus on how to implement cannabis tax policy to mitigate related harms. Therefore, the objective of this rapid review was to synthesize current evidence on the impact of cannabis taxation on purchasing behavior, use, and risk perceptions among U.S. adults.</p><p><strong>Methods: </strong>We systematically searched for peer-reviewed studies published in English (2014-present) in PubMed, SCOPUS, and Google Scholar. Two reviewers conducted independent screening of all relevant articles according to eligibility criteria using Covidence software. Out of the 1342 references identified, 1337 were not eligible for inclusion.</p><p><strong>Results: </strong>The 5 included studies examined excise cannabis taxes. Outcomes measured across the studies included cannabis use, cannabis demand, purchasing patterns, and perceptions. The data sources ranged from participant-level, state-level, and nationally representative data. One study found a negative association between taxes and past 30-day cannabis use, though statistically insignificant. A higher cannabis tax was linked to a decrease in cannabis demand. Another study demonstrated evidence of consumer stockpiling and increased cross-border substitution in response to higher cannabis tax rates. In terms of perceptions, policymakers rated taxes as a highly efficacious public health tool, and cannabis users viewed taxation as an important factor in their purchase decisions.</p><p><strong>Conclusions: </strong>The limited number of articles identified in this rapid review highlights the need for future studies to better understand consumer behavior and inform policy.</p>","PeriodicalId":17159,"journal":{"name":"Journal of studies on alcohol and drugs","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147662692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"E-Cigarette Use Trajectories and Respiratory Symptoms in Adolescents and Young Adults: Sustained Use Linked to Greater Symptom Frequency.","authors":"Abigail Shores, Hannah Appleseth, Ruochen Zhao, Megan E Roberts, Bo Lu, Jill M Singer, Dylan Wagner, Elizabeth G Klein, Loren E Wold, Marielle C Brinkman, Theodore L Wagener, Alayna P Tackett","doi":"10.15288/jsad.25-00388","DOIUrl":"10.15288/jsad.25-00388","url":null,"abstract":"<p><strong>Objective: </strong>This study cross-sequentially examined three measures of self-reported respiratory symptoms and nicotine e-cigarettes (EC) use adjusting for past 30-day use of cannabis/tobacco, COVID-19, and lifetime asthma at baseline (T1) and 12-months (T2).</p><p><strong>Method: </strong>Data came from the Emerging Adulthood Health Project. AYAs aged 15-24 (N= 751) self-reported demographics, nicotine/cannabis use, and respiratory symptoms. EC use at T1-T2 was categorized into a) never use, b) non-escalating, c) increasing, or d) sustained use. Binary and linear logistic regressions examined outcomes at T2.</p><p><strong>Results: </strong>At T1, participants (M age= 20.56 years [SD= 2.09 years]) were mostly female (n= 423 [56.6%]), White (n= 563 [75.3%]), and college students (n= 510 [68.0%]). In unadjusted analyses, EC sustained use had a significantly higher number of summed symptoms (binary; OR= 1.47, 95% CI [1.04, 2.07], p= .03) and more days with symptoms (OR= 1.64, 95% CI [1.16, 2.32], p= .006) compared to never EC use. In adjusted analyses, sustained EC use had higher American Thoracic Society Questionnaire scores (b=1.48, SE= 0.54, p=.0006) than never EC use, but the number of summed symptoms and days with symptoms became non-significant. Among participants experiencing any day with symptoms (N= 269), sustained (b= 2.05, SE=0.95, p=.03) and non-escalating use (b= 2.73, SE= 1.17, p= .02) was associated with more days with symptoms than never EC use in adjusted analyses.</p><p><strong>Conclusions: </strong>EC use behavior impacts self-reported frequency of respiratory symptoms among AYAs, with those who continue to use reporting more frequent symptoms, after adjusting for tobacco/cannabis use, COVID-19, and asthma.</p>","PeriodicalId":17159,"journal":{"name":"Journal of studies on alcohol and drugs","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13094720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147662689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}