Journal of studies on alcohol and drugs最新文献

{"title":"Predictors of the Rapid vs Longer Term Development of Opioid Use Disorder or Overdose among Clients Treated for an Alcohol Use Problem.","authors":"Zackary Falls, Xueqing Zhang, David M Jacobs, Gail Jette, Ashly E Jordan, Walter Gibson, Edward M Bednarczyk, Peter L Elkin, Kenneth E Leonard","doi":"10.15288/jsad.24-00401","DOIUrl":"https://doi.org/10.15288/jsad.24-00401","url":null,"abstract":"<p><strong>Objective: </strong>This study examines the differential predictive value of baseline characteristics of clients being treated for an alcohol problem with respect to the development of an Opioid Use Disorder (OUD) or Opioid Overdose (OD) within 1 year, between 1 and 4 years, and beyond 4 years after treatment.</p><p><strong>Method: </strong>A cohort of 87,172 patients treated for an alcohol use problem within state treatment centers was examined. We extracted the first OUD/OD diagnosis event within 1 year, between 1-4 years, and more than four years of the patient's first OASAS admission. We calculated odds ratios for all predictors and control variables with respect to OUD/OD events and compared the predictive values of these variables for the different periods.</p><p><strong>Results: </strong>Both sociodemographic and clinical factors were predictive of an OUD/OD overall and in most specific follow-up periods. Sociodemographic factors were more strongly associated with OUD/OD during follow-ups beyond 4 years, perhaps due to the increasing availability of opioids over time. Mental health and alcohol use severity factors were more strongly associated with OUD in the 1 year and 1-4 year periods, suggesting a rapid progression to OUD/OD.</p><p><strong>Conclusions: </strong>Both sociodemographic and clinical factors were predictive of a diagnosis of OUD/OD within a brief period of time, however they were only predictive of approximately 40% of those who would develop OUD/OD within any specific time period. These findings highlight the need for a more formal assessment of opioid use at treatment entry, and for the implementation of harm reduction measures throughout treatment.</p>","PeriodicalId":17159,"journal":{"name":"Journal of studies on alcohol and drugs","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robust Validation of Methods for Detecting Driving Under the Influence of Cannabis: Paths Forward.","authors":"Thomas D Marcotte, Robert L Fitzgerald","doi":"10.15288/jsad.25-00110","DOIUrl":"https://doi.org/10.15288/jsad.25-00110","url":null,"abstract":"","PeriodicalId":17159,"journal":{"name":"Journal of studies on alcohol and drugs","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Expanding Direct-to-Consumer Alcohol Home Delivery Policies: Evidence From 18 States of Increases in Alcohol Use and Consequences.","authors":"Jimikaye B Courtney, McKenna Roudebush, Rebecca S Williams, Melissa J Cox, Kurt M Ribisl","doi":"10.15288/jsad.24-00273","DOIUrl":"https://doi.org/10.15288/jsad.24-00273","url":null,"abstract":"<p><strong>Objective: </strong>After the COVID-19 pandemic onset, several U.S. states passed legislation to begin or expand direct-to-consumer (DTC) alcohol home delivery. We examined changes in DTC use and associations between DTC use, drinking patterns, and negative consequences by different DTC policies.</p><p><strong>Method: </strong>We conducted a cross-sectional, retrospective survey of 5,360 U.S. adults who consumed alcohol (ages 21-62 years), using an online Qualtrics survey panel. Participants were recruited from 18 states representing four DTC policy groupings pertaining to on- and off-premises outlets (no DTC, no change in existing DTC policy, new DTC policy, expanded DTC policy). DTC use and drinking patterns (average drinks/week, binge drinking days/month) were self-reported for four pandemic-related periods at pre- (2019-February 2020), early (March-May 2020), mid- (June 2020-March 2021), and late pandemic (April 2021-October 2023). Participants self-reported the total number of negative drinking consequences (out of 17) they experienced during the entire pandemic. Multivariate regressions examined time and policy group predicting DTC use, time and DTC use predicting drinking patterns, and DTC use and drinks/week predicting negative consequences.</p><p><strong>Results: </strong>Compared to adults in states with no delivery, odds of DTC use were highest among adults in states that expanded DTC policies (odds ratio [OR] = 2.11, 95% confidence interval [CI] [1.78, 2.50]). DTC use was associated with consuming approximately 4.43 (<i>p</i> < .001) more average drinks per week, more binge days per month (incidence rate ratio [IRR] = 1.33, 95% CI [1.27, 1.39]), and more negative consequences (IRR = 1.28, 95% CI [1.17, 1.39]), controlling for current drinking.</p><p><strong>Conclusions: </strong>Our findings suggest that expanding DTC delivery policies increased alcohol accessibility, and DTC use was associated with increases in excessive alcohol use and consequences. Such data can inform future decisions about states' DTC alcohol policies.</p>","PeriodicalId":17159,"journal":{"name":"Journal of studies on alcohol and drugs","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The US National Academies of Science, Engineering and Medicine was economical with the truth about alcohol and health.","authors":"Tim Stockwell, Isabella Priore, Pek Kei Im","doi":"10.15288/jsad.25-00075","DOIUrl":"https://doi.org/10.15288/jsad.25-00075","url":null,"abstract":"","PeriodicalId":17159,"journal":{"name":"Journal of studies on alcohol and drugs","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alcohol and Cannabis Use, Social Networks, and Non-Reservation American Indian / Alaska Native Emerging Adults: A Multi-level Dyadic Analysis.","authors":"David P Kennedy, Elizabeth J D'Amico, Ryan A Brown, Daniel L Dickerson, Carrie L Johnson, Nipher Malika","doi":"10.15288/jsad.24-00322","DOIUrl":"https://doi.org/10.15288/jsad.24-00322","url":null,"abstract":"<p><strong>Objective: </strong>The study investigated associations between social network characteristics and alcohol and cannabis (AC) use among non-reservation-living American Indian/Alaska Native (AI/AN) emerging adults (18-25 years old), with a focus on the potential protective influence of AI/AN traditional practices (e.g., dancing, storytelling, beading).</p><p><strong>Method: </strong>The study used a multi-level, multivariable dyadic approach to analyze personal network composition and network connectivity (centrality and density) from 470 AI/AN emerging adults living in non-reservation areas across the United States. Eligible participants completed an online survey, which included questions about social networks and AC use.</p><p><strong>Results: </strong>Findings indicated that network members who were similar in age, perceived to be friends, and lived nearby were more likely to be AC-use partners. Network members who shared AI/AN identity but did not engage in traditional practices were more likely to be AC-use partners than non-AI/AN network members. Analysis of network density demonstrated that having highly connected networks was associated with lower odds of respondents engaging in AC use with members of their networks. However, highly central network members had higher odds of AC use with respondents relative to those less central in the network. Findings were robust when controlling for respondent and network AC use.</p><p><strong>Conclusions: </strong>The study underscores the significance of the network context of AC use for non-reservation AI/AN emerging adults. The protective role of AI/AN traditional practices highlights the importance of strength-based intervention approaches that promote healthy social connections and traditional practices. Future research should test hypotheses longitudinally to inform more effective prevention strategies.</p>","PeriodicalId":17159,"journal":{"name":"Journal of studies on alcohol and drugs","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erythropoietin Attenuates Anxiety and Neurodevelopmental Neurotoxicity in Male Rats with Fetal Alcohol Spectrum Disorder via Increased BDNF-Positive Cells, Astrogliosis Suppression, and Reduced Hippocampal Cell Death.","authors":"Raheleh Rafaiee, Fahimeh Mohseni","doi":"10.15288/jsad.24-00389","DOIUrl":"https://doi.org/10.15288/jsad.24-00389","url":null,"abstract":"<p><strong>Objective: </strong>The term \"fetal alcohol spectrum disorder\" (FASD) refers to a variety of negative consequences that may develop in children born to women who have consumed alcohol during pregnancy. Anxiety disorders are common in FASD. Animals exposed to alcohol exhibit anxiety-like traits. Erythropoietin (EPO) is produced by the kidneys and liver. The synthesis of EPO by immature neurons also plays a crucial role in the embryonic stage. In addition, EPO inhibits astrogliosis and cell death while increasing the number of brain-derived neurotrophic factor (BDNF)-positive cells, which is linked to reductions in anxiety-like behavior and neuronal damage. This study investigated the protective effects of EPO on ethanol-induced neurotoxicity in the hippocampus of rat pups.</p><p><strong>Method: </strong>The intubation of the total daily dose of ethanol (5/27 g/kg/day) was started from PD 2 to PD 10 (corresponding to the third trimester of pregnancy in humans). After intubation, 1000 and 2000 U/kg EPO were injected subcutaneously. The elevated plus maze (EPM) was performed 39 days after the birth of the pups to determine the levels of anxiety. Immunohistochemical staining was then performed to determine GFAP and BDNF levels 40 days after birth. Nissl staining was done to measure necrotic cell death.</p><p><strong>Results: </strong>EPO administration significantly improved the anxious behavior associated with FASD (P< 0.001). EPO significantly increased BDNF levels (P< 0.001), decreased GFAP expression (P< 0.001), and attenuated alcohol neurotoxicity-induced necrotic cell death (P< 0.001).</p><p><strong>Conclusions: </strong>EPO treatment providing protection against ethanol neurotoxicity, which consequently leads to lower anxiety levels.</p>","PeriodicalId":17159,"journal":{"name":"Journal of studies on alcohol and drugs","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Veteran perspectives on treatment and recovery from co-occurring anxiety disorders, posttraumatic stress disorder and unhealthy alcohol use.","authors":"Anthony H Ecker, Haley Kolp, Lindsey Poe, Erin P Finley, Raven Pigee, Megan M Kelly, Drew A Helmer, Michael A Cucciare, Jeffery A Cully","doi":"10.15288/jsad.24-00278","DOIUrl":"https://doi.org/10.15288/jsad.24-00278","url":null,"abstract":"<p><strong>Objective: </strong>Veterans experience high rates of co-occurring anxiety disorders, posttraumatic stress disorder (PTSD), and unhealthy alcohol use. The goal of this study was to improve the understanding of veterans' beliefs about recovery from co-occurring anxiety/PTSD and alcohol use to direct treatment adaptation and implementation for providers.</p><p><strong>Methods: </strong>Semistructured qualitative interviews were conducted with 20 veterans, analyzed with rapid qualitative analysis and inductive coding.</p><p><strong>Results: </strong>Veterans' responses reflected themes related to improvement in functioning, including use of coping skills and communication skills, engagement in therapy, and connection with other veterans. Veterans also described barriers and facilitators related to effective treatment for both disorders.</p><p><strong>Conclusions: </strong>Specific elements in treatment (e.g., coping and communication skills) and broader considerations (e.g., building community among others in recovery) contribute to relationship and occupational recovery from co-occurring disorders among veterans. Ensuring that these factors are considered in behavioral treatment and treatment programs more broadly for veterans with co-occurring disorders has the potential to enhance functional recovery by aligning with veterans' perspectives and priorities.</p>","PeriodicalId":17159,"journal":{"name":"Journal of studies on alcohol and drugs","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How Cannabis and Alcohol Use Influence Sexual Behavior Among Men Who Have Sex with Men (MSM): A Secondary Data Analysis Using Ecological Momentary Assessment.","authors":"Maria J Bustamante, Tibor P Palfai, Jeffrey S Simmons, Stephen A Maisto, Brooke Z Beckius, Kawon Kim","doi":"10.15288/jsad.24-00172","DOIUrl":"https://doi.org/10.15288/jsad.24-00172","url":null,"abstract":"<p><strong>Background: </strong>Heavy drinking is common among men who have sex with men (MSM) and significantly increases HIV acquisition risk. MSM who report heavy drinking also report higher cannabis use, which has also been associated with sexual behaviors known to elevate HIV transmission risk. Despite evidence of associations at the between- subjects' level, the effects of alcohol and cannabis use on sexual risk behavior among MSM who engage in heavy drinking are largely unknown. The current study used ecological momentary assessment (EMA) to examine the between- and within-subject associations of heavy drinking, cannabis use and sexual behavior.</p><p><strong>Methods: </strong>This is a secondary data analysis of a study on alcohol intoxication on sexual decision making (Maisto et al., 2021) that included 115 MSM who reported cannabis use and were not using PrEP at the baseline. Participants reported daily alcohol and cannabis use and sexual activities over six weeks. Multilevel multinomial regression was used to evaluate how alcohol and cannabis use were associated with sexual behaviors.</p><p><strong>Results: </strong>Higher alcohol use was associated with higher rates of intercourse at the between-persons level and higher likelihood of all sexual behavior at the event-level. In contrast, cannabis use at the between-person level was associated with an increased rate of CAI relative to both anal intercourse with a condom as well as no sex. At the within-person level, cannabis was associated with increased likelihood of anal sex with or without a condom relative to no sex.</p><p><strong>Conclusions: </strong>Cannabis and alcohol may have independent effects on sexual risk behavior among MSM. Interventions addressing sexual health among MSM who engage in heavy drinking should also consider the additive risks of cannabis use.</p>","PeriodicalId":17159,"journal":{"name":"Journal of studies on alcohol and drugs","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commissioned Papers, Perspectives, and the Invisible College of Substance use Research.","authors":"Denis M McCarthy","doi":"10.15288/jsad.25-00084","DOIUrl":"https://doi.org/10.15288/jsad.25-00084","url":null,"abstract":"","PeriodicalId":17159,"journal":{"name":"Journal of studies on alcohol and drugs","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Associations Between Psychopathology Symptoms and Substance Use Across Race/Ethnicity and Gender: A Test of the Cross-Cultural Equivalence of Measurement.","authors":"William Rozum, Evelyn M Hernandez Valencia, Jodi M Sutherland Charvis, Chrystal Vergara-Lopez, Hector I Lopez-Vergara","doi":"10.15288/jsad.24-00285","DOIUrl":"10.15288/jsad.24-00285","url":null,"abstract":"<p><strong>Objective: </strong>The internalizing (e.g., depression/anxiety) pathway to substance use is a prominent hypothesis, but its evidence critiqued for neglecting correlated dimensions of mental health such as externalizing (e.g., aggressive, rule-breaking) and attention deficit/hyperactivity (ADH) problems. Furthermore, most research has been conducted in predominantly White samples limiting generalizability. We examine associations between substance use and psychopathology symptoms across intersectional race/ethnicity and gender identities.</p><p><strong>Method: </strong>Participants (<i>n</i>=1,187; 16.26% Black women, 17.61% Latina women, 15.67% White women, 16.68% Black men, 17.10% Latino men, and 16.68% White men) aged 18-26 completed online surveys. Alcohol and cannabis factors were indicated by six pattern of use items (e.g., frequency/quantity); psychopathology symptoms via the Adult Self-Report. Differential item functioning was tested before making comparisons in univariate and multivariate models.</p><p><strong>Results: </strong>Differential item functioning was detected; the degree of bias was modeled via partial metric invariance allowing for latent inferences. At the univariate level: externalizing symptoms predicted alcohol and cannabis across all groups except Black and Latino men, whereas internalizing and AHD symptoms predicted cannabis use in White women and White men only. In a multivariate model, internalizing symptoms inversely predicted alcohol use for White women and White men, externalizing symptoms predicted alcohol use in all groups except Latino men, and externalizing symptoms predicted cannabis use in all groups except Black women and Latino men. ADH showed no significant associations in the multivariate model.</p><p><strong>Conclusions: </strong>The conceptualized structure of mental health has implications for research on substance use. Intersectionality minded methods may provide a more generalizable scientific base.</p>","PeriodicalId":17159,"journal":{"name":"Journal of studies on alcohol and drugs","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143542420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}