Journal of separation science最新文献_第4页

Advancements in Multiple-Step On-Line Preconcentration Techniques for Enhanced Sensitivity in Capillary Electrophoresis 提高毛细管电泳灵敏度的多步在线预浓缩技术的进展

IF 2.8 3区工程技术

Journal of separation science Pub Date : 2024-09-20 DOI: 10.1002/jssc.202400519

Aemi Syazwani Abdul Keyon, NyukTing Ng, Michael Charles Breadmore

{"title":"Advancements in Multiple-Step On-Line Preconcentration Techniques for Enhanced Sensitivity in Capillary Electrophoresis","authors":"Aemi Syazwani Abdul Keyon, NyukTing Ng, Michael Charles Breadmore","doi":"10.1002/jssc.202400519","DOIUrl":"10.1002/jssc.202400519","url":null,"abstract":"<div>\u0000 \u0000 <p>Multiple-step on-line preconcentration, a combination of at least two stacking techniques has been developed to increase the sensitivity in capillary electrophoresis (CE) for analytes in various samples. It is usually conducted sequentially, or in some cases, synergistically, where different stacking modes occur simultaneously. Multiple-step techniques allow simultaneous preconcentration and separation of various kinds of analytes in different complex samples in a single CE run. This review aims to provide recent advances in multiple-step on-line preconcentration techniques in CE. We critically review technical papers published for the last 7 years up until July 2024, subsequently organized according to the combination of the main stacking techniques, that is, field amplification, large volume sample stacking, transient isotachophoresis, micelle to solvent or micelle to cyclodextrin stacking, and others. The procedures, fundamental mechanism, analytical figures of merits achieved, and their feasibility for complicated sample matrices are reviewed.</p>\u0000 </div>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142273169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thermo-Assisted Deep Eutectic Solvent Based on Dispersive Liquid-Liquid Microextraction for Preconcentration of Phthalate Esters in Water Samples and Determination by Gas Chromatography With Flame Ionization Detection 基于分散液-液微萃取技术的热助深共晶溶剂用于预富集水样中的邻苯二甲酸酯并通过火焰离子化检测气相色谱法进行测定

IF 2.8 3区工程技术

Journal of separation science Pub Date : 2024-09-20 DOI: 10.1002/jssc.202300878

Khosrou Abdi, Maryam Ezoddin, Venous Novasari, Navid Lamei

{"title":"Thermo-Assisted Deep Eutectic Solvent Based on Dispersive Liquid-Liquid Microextraction for Preconcentration of Phthalate Esters in Water Samples and Determination by Gas Chromatography With Flame Ionization Detection","authors":"Khosrou Abdi, Maryam Ezoddin, Venous Novasari, Navid Lamei","doi":"10.1002/jssc.202300878","DOIUrl":"10.1002/jssc.202300878","url":null,"abstract":"<div>\u0000 \u0000 <p>A thermo-assisted deep eutectic solvent (DES) based on dispersive liquid-liquid microextraction followed by gas chromatography with flame ionization detection was developed for the analysis of five phthalate esters in different water samples. In the procedure involved, a DES composed of lidocaine, an amphiphilic amine, and oleic acid, was mixed with the sample assisted by ultrasound, and phase separation was achieved with increasing temperature. The heating of the extraction system induced the change of acid-base properties of the DES components. Thus, the formation of microdroplets of DES in the sample was provided, and two phases were separated. The structure of the upper hydrophobic layer was characterized by Fourier-transform infrared spectroscopy. Also, the amount of water in the DES phase was analyzed by mass spectrometer and Karl Fischer titration. Some critical variables on the extraction yield were assessed. The proposed method achieved 1.2–1.3 and 4.1–4.3 µg/L for limits of detection and limits of quantification, respectively. The intra-day and inter-day percentage relative standard deviations (<i>n</i> = 5) were determined to be in the range of 4.2–6.2% and 5.1–7.2%, respectively. Ultimately, this method analyzed the five phthalate esters in different water samples with high recoveries.</p>\u0000 </div>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142273170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Dual Membrane Electrodialytic Phosphoric Acid Eluent Generator for Ion Exclusion Chromatography—A Gas-Free Electrodialytic Phosphoric Acid Generator 用于离子排阻色谱法的双膜电解磷酸流体发生器--无气电解磷酸发生器

IF 2.8 3区工程技术

Journal of separation science Pub Date : 2024-09-20 DOI: 10.1002/jssc.202400536

Xiaolu Sun, Jingwen Tang, Weiqing Chen, Feifang Zhang, Bingcheng Yang

引用次数: 0

Boric Acid Functionalized Hypercrosslinked Polymers for Selective Extraction of Trace Catecholamines and Their Metabolites in Rat Serum 用于选择性萃取大鼠血清中痕量儿茶酚胺及其代谢物的硼酸功能化超交联聚合物

IF 2.8 3区工程技术

Journal of separation science Pub Date : 2024-09-20 DOI: 10.1002/jssc.202400418

Zhiyu Zhang, Cheng Yang, Di Zhao, Yuanqing Zhao, Lixin Li, Zhonghua Li, Zhenqiang Zhang, Kai Hu

{"title":"Boric Acid Functionalized Hypercrosslinked Polymers for Selective Extraction of Trace Catecholamines and Their Metabolites in Rat Serum","authors":"Zhiyu Zhang, Cheng Yang, Di Zhao, Yuanqing Zhao, Lixin Li, Zhonghua Li, Zhenqiang Zhang, Kai Hu","doi":"10.1002/jssc.202400418","DOIUrl":"10.1002/jssc.202400418","url":null,"abstract":"<div>\u0000 \u0000 <p>Abnormal levels of catecholamine (CA) neurotransmitters and their metabolites in biological fluids can lead to various neurological disorders. Herein, a boric acid-functionalized hypercrosslinked polymer was prepared and utilized as a sorbent for the dispersive solid-phase extraction of CAs and their metabolites in rat serum. By combination with a high-performance liquid chromatography-fluorescence detector, the extraction parameters for the seven target analytes were optimized. Under the optimal extraction condition, the methodology for the quantitative analysis of CAs and their metabolites in rat serum samples was established. The limits of detection and limits of quantification were found to be in the ranges of 0.010–0.015 and 0.033–0.050 ng/mL, respectively. The results demonstrated satisfactory recoveries, with values ranging from 88.02% to 113.27%, accompanied by relative standard deviations within the range of 2.69%–9.59%. In addition, the method showed good anti-interference ability (matrix effect ranged from 2.64% to 18.07%). The developed method was validated for the determination of CAs and their metabolites in normal and Alzheimer's disease model rats’ serum, which proved the promising application of the method for CAs neurotransmitter analysis in biological samples.</p>\u0000 </div>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142273171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent advances in liquid chromatography-tandem mass spectrometry for the detection of thyroid hormones and thyroglobulin in clinical samples: A review 液相色谱-串联质谱法检测临床样本中甲状腺激素和甲状腺球蛋白的最新进展：综述

IF 2.8 3区工程技术

Journal of separation science Pub Date : 2024-09-18 DOI: 10.1002/jssc.202400466

Yuting Jin, Taiyu Zhai, Ying Wang, Jiuyan Li, Tingting Wang, Jing Huang

{"title":"Recent advances in liquid chromatography-tandem mass spectrometry for the detection of thyroid hormones and thyroglobulin in clinical samples: A review","authors":"Yuting Jin, Taiyu Zhai, Ying Wang, Jiuyan Li, Tingting Wang, Jing Huang","doi":"10.1002/jssc.202400466","DOIUrl":"https://doi.org/10.1002/jssc.202400466","url":null,"abstract":"<p>Thyroid hormones (THs), including triiodothyronine (T3), thyroxine (T4), and their metabolites, are essential for regulating development, growth, and energy metabolism. Thyroglobulin (Tg) produced by thyroid follicular cells acts as an essential substrate for TH synthesis. The combination of THs with Tg is a widely used serological laboratory test for thyroid function assessment. Early detection and timely intervention are significant for preventing and managing thyroid disease. In recent years, liquid chromatography-tandem mass spectrometry (LC-MS/MS) has emerged as a powerful tool for the precise detection of small molecular analytes and steroid hormones in clinical practice as a result of its high sensitivity and specificity. While LC-MS/MS has been increasingly used for detecting THs and Tg recently, its application in clinical practice is still in its early stages. Recent advances in the assessment of thyroid metabolism using LC-MS/MS in clinical samples published during 2004–2023 were reviewed, with a special focus on the use of this technique for quantifying molecules involved in thyroid diseases.</p>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142273000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In-tube solid-phase microextraction of polycyclic aromatic hydrocarbons from refinery water samples using UiO-66/polyacrylonitrile electrospun nanofibers followed by high-performance liquid chromatography-ultraviolet detection 使用 UiO-66/ 聚丙烯腈电纺纳米纤维对炼油厂水样中的多环芳烃进行管内固相微萃取，然后进行高效液相色谱-紫外检测

IF 2.8 3区工程技术

Journal of separation science Pub Date : 2024-09-14 DOI: 10.1002/jssc.202400296

Seyedeh Sara Nasrollahi, Yadollah Yamini

{"title":"In-tube solid-phase microextraction of polycyclic aromatic hydrocarbons from refinery water samples using UiO-66/polyacrylonitrile electrospun nanofibers followed by high-performance liquid chromatography-ultraviolet detection","authors":"Seyedeh Sara Nasrollahi, Yadollah Yamini","doi":"10.1002/jssc.202400296","DOIUrl":"10.1002/jssc.202400296","url":null,"abstract":"<p>A simple and quick fiber-in-tube solid-phase microextraction (FIT-SPME) was introduced for the extraction and determination of nine polycyclic aromatic hydrocarbons followed by a high-performance liquid chromatography-ultraviolet detector in refinery water samples. For this purpose, a water-resistant metal-organic framework with a high surface area called UiO-66 has been applied in the form of an electrospun coating on stainless steel wires. After that, all the fibers were packed in the lumen of a stainless-steel tube to make the extraction phase. Both one variable at a time and experimental design methods have been used to optimize effective parameters on FIT-SPME. Under optimum conditions, the method demonstrated good linearity between 0.5 and 1000.0 µg/L with a coefficient of determination greater than 0.9906. Furthermore, the limits of detection values ranged from 0.2 to 1.5 µg/L. The intra-day and inter-day relative standard deviations were < 8.4% and < 9.7%, respectively. Lastly, the proposed method was applied to extract and determine analytes in four refinery water samples as well as surface water containing high total dissolved solids, and well waters where satisfactory results have been obtained.</p>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142233182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The analysis of e-liquids: A study on chemical diversity and metal content using gas chromatography-mass spectrometry and inductively coupled plasma-mass spectrometry 电子液体分析：使用气相色谱-质谱法和电感耦合等离子体-质谱法研究化学多样性和金属含量

IF 2.8 3区工程技术

Journal of separation science Pub Date : 2024-09-10 DOI: 10.1002/jssc.202400443

Matjaž Rantaša, David Majer, Matjaž Finšgar

{"title":"The analysis of e-liquids: A study on chemical diversity and metal content using gas chromatography-mass spectrometry and inductively coupled plasma-mass spectrometry","authors":"Matjaž Rantaša, David Majer, Matjaž Finšgar","doi":"10.1002/jssc.202400443","DOIUrl":"https://doi.org/10.1002/jssc.202400443","url":null,"abstract":"<p>This work aimed to determine the chemical composition of 22 e-liquids available on the Slovenian market. Four different gas chromatography (GC) sample introduction techniques; headspace-GC-mass spectrometry (HS-GC-MS), liquid injection-GC-MS (LI-GC-MS), HS-solid-phase microextraction-GC-MS (HS-SPME-GC-MS), and direct-immersion-SPME-GC-MS (DI-SPME-GC-MS) were employed for qualitative analysis. Various experimental parameters were assessed for each GC sample introduction technique to maximize compound identification. Despite e-liquid packaging reporting a maximum of eight compounds, GC-MS identified more compounds in most samples, especially in menthol-flavored (58 identifiable compounds by HS-SPME-GC-MS), followed by nicotine-containing and fruit-flavored samples. HS-SPME-GC-MS identified the highest number of compounds, followed by HS-GC-MS, DI-SPME-GC-MS, and LI-GC-MS. Nicotine quantification in six samples was performed by LI-GC-MS with dilution in methanol. Nicotine concentration in samples ranged from 16.5 ± 0.5 to 18.5 ± 0.4 mg/mL, which was below the declared concentration of 20 mg/mL. Additionally, quantitative analysis of metals in e-liquids was performed by inductively coupled plasma-MS after microwave-assisted wet acid digestion. Iron was the most abundant metal, with its content ranging from 0.024 to 0.354 µg/g. Barium, bismuth, copper, and tin were also determined in several e-liquids.</p>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jssc.202400443","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142169942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The analysis of e-liquids: A study on chemical diversity and metal content using gas chromatography-mass spectrometry and inductively coupled plasma-mass spectrometry 电子液体分析：使用气相色谱-质谱法和电感耦合等离子体-质谱法研究化学多样性和金属含量

IF 2.8 3区工程技术

Journal of separation science Pub Date : 2024-09-10 DOI: 10.1002/jssc.202400443

Matjaž Rantaša, David Majer, Matjaž Finšgar

{"title":"The analysis of e-liquids: A study on chemical diversity and metal content using gas chromatography-mass spectrometry and inductively coupled plasma-mass spectrometry","authors":"Matjaž Rantaša, David Majer, Matjaž Finšgar","doi":"10.1002/jssc.202400443","DOIUrl":"https://doi.org/10.1002/jssc.202400443","url":null,"abstract":"<p>This work aimed to determine the chemical composition of 22 e-liquids available on the Slovenian market. Four different gas chromatography (GC) sample introduction techniques; headspace-GC-mass spectrometry (HS-GC-MS), liquid injection-GC-MS (LI-GC-MS), HS-solid-phase microextraction-GC-MS (HS-SPME-GC-MS), and direct-immersion-SPME-GC-MS (DI-SPME-GC-MS) were employed for qualitative analysis. Various experimental parameters were assessed for each GC sample introduction technique to maximize compound identification. Despite e-liquid packaging reporting a maximum of eight compounds, GC-MS identified more compounds in most samples, especially in menthol-flavored (58 identifiable compounds by HS-SPME-GC-MS), followed by nicotine-containing and fruit-flavored samples. HS-SPME-GC-MS identified the highest number of compounds, followed by HS-GC-MS, DI-SPME-GC-MS, and LI-GC-MS. Nicotine quantification in six samples was performed by LI-GC-MS with dilution in methanol. Nicotine concentration in samples ranged from 16.5 ± 0.5 to 18.5 ± 0.4 mg/mL, which was below the declared concentration of 20 mg/mL. Additionally, quantitative analysis of metals in e-liquids was performed by inductively coupled plasma-MS after microwave-assisted wet acid digestion. Iron was the most abundant metal, with its content ranging from 0.024 to 0.354 µg/g. Barium, bismuth, copper, and tin were also determined in several e-liquids.</p>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jssc.202400443","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142169941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Low swelling and high mechanical strength organosilane hybrid polydivinylbenzene microspheres for hydrophilic interaction chromatography applications 用于亲水相互作用色谱的低膨胀、高机械强度有机硅杂化聚二乙烯基苯微球

IF 2.8 3区工程技术

Journal of separation science Pub Date : 2024-09-09 DOI: 10.1002/jssc.202400462

Yang Yang, Yuexin Li, Yang Zhao, Changyu Cai, Xinmiao Liang, Yanxiong Ke

引用次数: 0

Construction of amine-rich coating utilizing amine curing reaction of triglycidyl isocyanate with triethylenetetramine on the surface of poly(styrene-divinylbenzene) microspheres for preparation of anion exchange stationary phase 利用异氰酸三缩水甘油酯与三乙烯四胺在聚（苯乙烯-二乙烯基苯）微球表面的胺固化反应构建富胺涂层，用于制备阴离子交换固定相

IF 2.8 3区工程技术

Journal of separation science Pub Date : 2024-09-09 DOI: 10.1002/jssc.202400369

Junwei Liu, Yuqi Yan, Haojie Li, Shiting Zhang, Guoqing Wang, Yu-an Sun, Yan Zhu

{"title":"Construction of amine-rich coating utilizing amine curing reaction of triglycidyl isocyanate with triethylenetetramine on the surface of poly(styrene-divinylbenzene) microspheres for preparation of anion exchange stationary phase","authors":"Junwei Liu, Yuqi Yan, Haojie Li, Shiting Zhang, Guoqing Wang, Yu-an Sun, Yan Zhu","doi":"10.1002/jssc.202400369","DOIUrl":"10.1002/jssc.202400369","url":null,"abstract":"<p>Epoxy resins, as important thermosetting polymers, exhibit excellent adhesion to various substrates. In view of this, reticulate coating of triglycidyl isocyanate with triethylenetetramine was introduced onto the surface of poly(styrene-divinylbenzene) utilizing amine curing reaction to obtain poly(styrene-divinylbenzene)@triglycidyl isocyanate-triethylenetetramine composite microspheres. The amino groups and epoxy groups of triglycidyl isocyanate-triethylenetetramine endowed poly(styrene-divinylbenzene) with good reactivity, which could be quaternized under mild conditions to obtain an anion exchange chromatographic stationary phase. The quaternized poly(styrene-divinylbenzene)@triglycidyl isocyanate-triethylenetetramine was characterized by scanning electron microscope, Fourier-transform infrared spectroscopy, N<sub>2</sub> adsorption-desorption experiment, et al. The chromatographic performance of the customized column was evaluated by separating seven conventional anions, organic weak acids, and carbohydrates. Poly(styrene-divinylbenzene)@triglycidyl isocyanate-triethylenetetramine possesses the uniform size of poly(styrene-divinylbenzene) microspheres and good reactivity of triglycidyl isocyanate-triethylenetetramine, which offers a flexible strategy for the preparation of anion exchange stationary phase. The column exhibits excellent chemical and mechanical stability and chromatographic performance. Finally, the column was successfully applied for the determination of nitrite in pickles.</p>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142160174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0