Journal of separation science最新文献

{"title":"Deep Eutectic Solvents Selection for the Extraction of Phlorizin from Malus hupehensis Using Conductor-like Screening Model for Real Solvents","authors":"Xu Cai,&nbsp;Yuanguo Xiong,&nbsp;Qiyu Sun,&nbsp;Meiling Wang,&nbsp;Yan Peng,&nbsp;Jintian Tang,&nbsp;Dan Li,&nbsp;Gang Liu","doi":"10.1002/jssc.70290","DOIUrl":"10.1002/jssc.70290","url":null,"abstract":"<div>\u0000 \u0000 <p>Deep eutectic solvents (DESs), composed of hydrogen bond donors (HBDs) and hydrogen bond acceptors (HBAs), are efficient and widely applied solvents for extracting active compounds. Phlorizin (PHL), as the main component of <i>Malus hupehensis</i>, plays a critical role in the preparation of a DES-based extract. The appropriate option of DES is a primary consideration in the extraction of PHL from <i>M. hupehensis</i>. According to the chemical structural characteristics of PHL and solvent, the conductor-like screening model for real solvents is applied to select a DES. Lactic acid (LA) and betaine (BET) with a molar ratio of 2:1 and 40 wt% water are determined, and the extraction results are consistent with the predicted solubility of PHL in selected DESs. Thus, the optimal extraction conditions are identified as liquid-material ratio 40 mL/g, extraction time 50 min, and extraction temperature 60°C, resulting in the maximum yield of 14.07 ± 0.14%. As evidenced by Fourier-transform infrared and proton nuclear magnetic resonance spectra, PHL acts as an HBD and competitively interacts with HBA sites that are occupied by LA. Molecular dynamics simulations demonstrate the hydrogen bonding interactions between PHL and DES, consisting of LA and BET, with the lowest interaction energy of –135.6 kJ/mol. Therefore, the conductor-like screening model for real solvents is an available strategy to rapidly and efficiently select the appropriate DES on the basis of the thermodynamic characteristics. DESs can effectively extract PHL from <i>M. hupehensis</i>, and the DES-based extract of <i>M. hupehensis</i> with antioxidant activity provides a foundation for further application of DESs.</p>\u0000 </div>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":"48 10","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145212872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microplastic and Nanoplastic Analysis: From Pyrolysis Gas Chromatography-Mass Spectrometry to Pyrolysis Two-dimensional Gas Chromatography-Mass Spectrometry—A Critical Review","authors":"Géraldine Dumont,&nbsp;Anaïs Rodrigues,&nbsp;Milica Velimirovic,&nbsp;Siebe Lievens,&nbsp;Jan Jordens,&nbsp;Jean-François Focant,&nbsp;Pierre-Hugues Stefanuto","doi":"10.1002/jssc.70287","DOIUrl":"10.1002/jssc.70287","url":null,"abstract":"<div>\u0000 \u0000 <p>The growing environmental and health concerns regarding micro- and nanoplastics (MNPs) have prompted the development of advanced analytical methods for accurate characterization and quantification. Pyrolysis-gas chromatography-mass spectrometry (Py-GC-MS) enables polymer identification by their thermal destruction into characteristic fragments. However, the small particle size and interferences originating from complex sample matrices complicate its analysis. Therefore, the integration of comprehensive two-dimensional GC (GC×GC) would improve separation efficiency and sensitivity and provide a detailed composition of environmental and biological samples. This review documents (i) the evolution of Py-GC-MS and (ii) the potential to resolve overlapping compounds, improving quantification accuracy, and detecting minor plastic compounds and degradation byproducts by comprehensive GC×GC-MS as a crucial approach to measure MNPs. Despite the documented advancements, key challenges persist. The lack of standardized protocols for sample preparation and calibration, impeding the comparability of studies, is of prime concern. The massive presence of (in)organic interferences even further accentuates the absence of internal standards in terms of quantification. Therefore, to improve analytical reliability, future research should focus on developing standardized methodologies, improving detection sensitivity for NPs, and incorporating complementary approaches. Additionally, coupling GC×GC with time-of-flight MS further strengthens its capability to provide higher analytical resolution power and better chemical description of pyrolyzates. This review highlights the crucial role of advanced Py and chromatography-based techniques in supporting the analytical description of the extent of plastic pollution and in supporting evidence-based policymaking and successful mitigation efforts to protect ecosystems and public health.</p>\u0000 </div>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":"48 10","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145212906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantifying Biomolecular Interactions in High-Conductivity Samples With Capillary Electrophoresis.","authors":"Miyuru De Silva, Samson Aruna, Bhagya Samarakoon, Rebecca J Whelan","doi":"10.1002/jssc.70288","DOIUrl":"https://doi.org/10.1002/jssc.70288","url":null,"abstract":"<p><p>Capillary electrophoresis (CE) is a powerful tool for studying biomolecular interactions due to its high speed, low sample consumption, and adaptability. However, challenges arise when sample buffers possess higher conductivity than the background electrolyte (BGE), leading to peak distortions and reduced measurement accuracy in binding assays such as affinity probe CE and nonequilibrium CE of equilibrium mixtures. This study investigates these effects using a combination of simulation and experiment, focusing on aptamer-protein interactions. Moderate conductivity mismatches (e.g., sample buffer = 2 × tris glycine, BGE = 30 mM tricine) led to peak splitting artifacts, whereas large mismatches (e.g., sample buffer = phosphate-buffered saline, BGE = 30 mM tricine) produced broad, indistinct peaks, obscuring free and bound species. Simulations revealed that these artifacts arise from analyte ions trapped in high-conductivity sample plugs and are exacerbated by longer injection times. Experimental results confirmed that reducing plug length and selectively excluding artifact peaks during analysis improves quantification accuracy. When traditional separation fails under high-conductivity conditions, we propose an alternative method based on quantifying the \"de-stacked\" fraction of aptamers escaping the sample zone. This approach yielded values for the dissociation constant (K_d) and Hill coefficient (n) comparable to those obtained using fluorescence anisotropy, demonstrating its viability. The method was further validated by measuring the binding of an integrin-targeting aptamer (S10yh2) to human serum albumin. Overall, this work provides practical guidelines and analytical strategies for accurate quantification of binding interactions in CE under nonideal conductivity conditions, broadening the applicability of CE for bioanalytical research.</p>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":"48 10","pages":"e70288"},"PeriodicalIF":2.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145244805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparation of In-Situ Multifunctional Silicon Self-Assembled Molecularly Imprinted Polymers for Selective Extraction of Protein.","authors":"Kaimin Gong, Xiaofei Wang, Yunfeng Bai, Xueqin Ma, Guoning Chen","doi":"10.1002/jssc.70291","DOIUrl":"https://doi.org/10.1002/jssc.70291","url":null,"abstract":"<p><p>The sol-gel method demonstrates significant potential for fabricating protein molecularly imprinted polymers (MIPs). In order to maintain good protein structure and provide more recognition functional groups during the preparation of protein MIPs. In this study, an exceptionally mild sol-gel protocol for protein MIPs synthesis was developed, in which no catalyst or organic solvent was employed and abundant recognition groups were introduced through in-situ derivatization. This method has been applied in the preparation of MIPs using lysozyme (lys) as a template. The developed MIPs exhibit high adsorption capacity and selectivity toward lys. The generation of the imprinting effect was successfully demonstrated by observing the surface morphology and evaluating the physical/chemical properties of the synthesized MIPs. In subsequent adsorption experiments, MIPs also showed excellent adsorption performance (389.85 mg/g) and quickly reached the adsorption equilibrium within 60 min. In addition, the selectivity of MIPs for lys was improved by the sol-gel imprinting process, and good reusability was observed after five adsorption-desorption cycles. The method was also successfully applied to isolate lys from egg white samples. This work demonstrates the great potential of the sol-gel strategy in the field of molecular imprinting.</p>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":"48 10","pages":"e70291"},"PeriodicalIF":2.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145244848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of Air-assisted Liquid-Liquid Microextraction in the Primary Amine-based Supramolecular Solvent for Determination of Tricyclic Antidepressants Prior to High-Performance Liquid Chromatography-Ultraviolet Detection.","authors":"Masumeh Sabaghi, Maryam Ezoddin, Mahmoud Ghazi-Khansari, Mahdieh Seyed Javadi, Khosrou Abdi","doi":"10.1002/jssc.70254","DOIUrl":"https://doi.org/10.1002/jssc.70254","url":null,"abstract":"<p><p>This study developed an air-assisted liquid-liquid microextraction method using a primary amine-based supramolecular solvent (SUPRAS) and a monoterpenoid as a coacervation agent to determine two tricyclic antidepressants (amitriptyline and nortriptyline) from human plasma and urine samples prior to high-performance liquid chromatography analysis. The extraction of two antidepressant drugs was performed using a micellar solution of the primary amine (1-octylamine) as an amphiphile. A monoterpenoid (thymol) was utilized to initiate the coacervation process. The homogeneous solution of the SUPRAS was dispersed into the aqueous sample phase using air bubbles introduced through a syringe. The important characteristic of the suggested SUPRAS is the elimination of toxic solvents, such as tetrahydrofuran, and the removal of dispersive solvents. The experimental parameters, such as primary amine type, monoterpenoid type, extraction cycle number, and pH, were investigated. The limits of detection (signal-to-noise ratio [S/N] = 3) and quantification (S/N = 10) were achieved to be 0.5-0.6 and 1.5-1.8 µg/L with a linear range of 1.5-4000 and 1.8-4000 µg/L in urine and plasma samples. The percentage relative standard deviation values (n = 5) were 2.9%-3.5% for amitriptyline and 4.1%-4.2% for nortriptyline. The proposed method has been applied successfully to the spiked urine and plasma samples, achieving recoveries in the range of 93.1%-95.2.</p>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":"48 10","pages":"e70254"},"PeriodicalIF":2.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145244777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination and Confirmation of Triazine Herbicides and Their Degradation Products in Seawater by Liquid Chromatography Coupled With Quadrupole/Exactive Orbitrap Mass Spectrometry","authors":"Xiaojie Sun,&nbsp;Lihong Xing,&nbsp;Mengmeng Guo,&nbsp;Anqi Jin,&nbsp;Yanna Yang,&nbsp;Zhaoxin Li,&nbsp;Lin Yao","doi":"10.1002/jssc.70263","DOIUrl":"10.1002/jssc.70263","url":null,"abstract":"<div>\u0000 \u0000 <p>Herbicides seriously threaten the ecosystem due to their wide application and environmental migration. Nevertheless, the detection and confirmation methods of triazine herbicides and their degradation products in seawater matrix remain deficient, which affect the accuracy of marine environment and aquatic organism safety risk assessment. In the present study, rapid analysis and accurate identification of seven triazine herbicides and six degradation products in seawater were achieved for the first time, based on hydrophilic-lipophilic balance solid-phase extraction combined with scanning pattern of full scan mass spectrometry-data-dependent mass spectrometry² and internal standard calibration by liquid chromatography coupled with Quadrupole/Exactive Orbitrap high-resolution mass spectrometry. The results showed a good linear relationship for the tested compounds with <i>R</i>² &gt; 0.995. The limits of detection and quantitation of the method were 5.0 and 20 ng/L, respectively. The recoveries of the 13 compounds ranged from 70.0% to 120% when spiked at three levels, and the relative standard deviations were all less than 15% (<i>n</i> = 6). This method has been successfully applied to the detection of triazine herbicide in 34 real seawater samples, and the presence of prometryn, 2-hydroxy prometryn, desisopropyl prometryn, atrazine, and desisopropyl atrazine in positive seawater samples was confirmed by Quadrupole/Exactive Orbitrap high-resolution mass spectrometry. Therefore, the present method has promising application prospects in the detection and positive identification of pollutants in seawater, with high accuracy, sensitivity, and good reproducibility.</p>\u0000 </div>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":"48 10","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancement of GC–MS Signal for Environmental Pollutants via the Transient Matrix Effect","authors":"Michal P. Dybowski","doi":"10.1002/jssc.70285","DOIUrl":"10.1002/jssc.70285","url":null,"abstract":"<div>\u0000 \u0000 <p>Matrix effects in gas chromatography (GC) are typically regarded as an analytical drawback, as co-eluting compounds can distort analyte quantification. This study demonstrates that a transient matrix effect can be deliberately induced to enhance GC–MS sensitivity for environmental pollutants. Four classes of high-boiling protectants—alcohols, amines, carboxylic acids, and polyethylene glycols (PEGs)—were systematically evaluated for their ability to increase detector response for polycyclic aromatic hydrocarbons (PAHs), chlorophenols, and nitrophenols. The influence of protectant type, sample solvent, injector temperature, and initial column temperature on signal enhancement was investigated. Among all protectants, PEGs yielded the highest improvements, with average signal increases of 280% for PAHs and 380% for chlorophenols and nitrophenols. The transient nature of the effect was confirmed through alternating injections, ensuring no cumulative influence on subsequent analyses. Application of the QuEChERS method to water and soil samples showed comparable enhancements, with minimal interference from matrix components. Method validation for PEG-400 confirmed excellent linearity (<i>R</i>² &gt; 0.998), two- to threefold lower LODs, and high precision (RSD &lt; 4.3%), demonstrating robustness and reproducibility. Leveraging a controlled transient matrix effect, this approach achieves several-fold improvement in detection limits without altering chromatographic hardware, providing a simple and adaptable tool for trace-level environmental monitoring.</p>\u0000 </div>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":"48 10","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Green Method for Seized Drug Screening Using a Portable Liquid Chromatograph With UV-LED Detection","authors":"Jayda Barber,&nbsp;Ira S. Lurie","doi":"10.1002/jssc.70276","DOIUrl":"10.1002/jssc.70276","url":null,"abstract":"<div>\u0000 \u0000 <p>Portable instruments allow for on-site real-time analyses and generally take up less resources compared to standard-sized instruments. In this project, we tested the suitability of a portable liquid chromatograph for seized drug screening and how it, alone, may fulfill the requirements set forth by the Scientific Working Group for the Analysis of Seized Drugs (SWGDRUG). For this study, we used a portable liquid chromatograph, which employed a dual column system with on-column dual UV-LED detection. All 16 drugs representing different drug classes could be identified by a combination of dual relative retention times and dual UV absorbance ratios. Most classical drugs, which represent non-novel psychoactive compounds, could be identified based on the SWGDRUG guidelines. These results suggest the potential for liquid chromatography to be performed in the field using portable devices and to provide a greener alternative to traditional liquid chromatography due to greatly reduced solvent consumption.</p>\u0000 </div>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":"48 10","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying Oxysterols Associated With Age and Diet in Mice Using Optimized Reversed-phase Liquid Chromatography-Mass Spectrometry (RPLC-MS)","authors":"Indhumathy Subramaniyan,&nbsp;Benjamin Barr,&nbsp;Ninh M. La-Beck,&nbsp;Benjamin G. Janesko,&nbsp;Lauren Gollahon,&nbsp;Li Li","doi":"10.1002/jssc.70274","DOIUrl":"10.1002/jssc.70274","url":null,"abstract":"<p>Structurally similar oxysterols such as 7α-hydroxycholesterol, 7β-hydroxycholesterol, and 7-ketocholesterol; 5,6α- and 5,6β-epoxycholesterol; and 24(<i>R</i>/<i>S</i>)-hydroxy cholesterol, 25-hydroxy cholesterol, and 27-hydroxycholesterol are traditionally difficult to resolve using reversed-phase liquid chromatography (RPLC). We present a simple yet highly optimized method for the simultaneous quantification of eight oxysterols using RPLC coupled with mass spectrometry (MS) without derivatization. Optimal separation of most oxysterols was achieved at a lower column temperature (25°C), with specific combinations of stationary and mobile phases enhancing resolution, particularly for isomeric pairs such as 7α-/7β-OHC, 5,6α-/5,6β-EC, 24 R/S-OHC, and 25-OHC. Although certain analytes (e.g., 24<i>S</i>-OHC and 27-OHC) remained challenging to separate due to similar retention behavior, they were distinguishable by their unique MRM transitions. We applied this method to investigate oxysterol changes in a longitudinal mouse study comparing a normal diet to a high-fat diet. Liver and brain samples were analyzed, revealing distinct distribution patterns between the two organs. Notably, 24(<i>S</i>)-hydroxycholesterol levels, a signature cholesterol metabolite exclusively produced in the brain, increased with age independent of diet. In contrast, 5,6α-epoxycholesterol production in the liver was influenced by both age and dietary factors. Our method provides a robust tool for studying oxysterol variation and its implications in aging and diet, offering new insights into cholesterol-derived lipid regulation across different physiological conditions.</p>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":"48 10","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/epdf/10.1002/jssc.70274","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simultaneous Determination of Vancomycin and Creatinine by Dried Plasma Spotsampling via LC-MS/MS","authors":"Chang Sun,&nbsp;Zhihui Sun,&nbsp;Wei Xia,&nbsp;Haiwei Cao,&nbsp;Yijia Qin,&nbsp;Yingying Feng,&nbsp;Zhengchao Ji,&nbsp;Jing Huang,&nbsp;Yanyan Li","doi":"10.1002/jssc.70279","DOIUrl":"10.1002/jssc.70279","url":null,"abstract":"<div>\u0000 \u0000 <p>Routine monitoring of vancomycin drug concentrations is crucial for optimizing dosages to ensure therapeutic efficacy and minimize adverse effects. Vancomycin's clearance is highly correlated with creatinine clearance. However, in developing countries, the majority of hospitals lack the on-site capacity to measure vancomycin concentrations. Dried plasma spots have emerged as an innovative alternative for biological sample collection. Dried plasma spots facilitate the convenient and rapid acquisition of plasma samples, which are highly suitable for both storage and transportation, and can be dispatched to vancomycin testing laboratories. This study presents a validated methodology for the simultaneous quantification of vancomycin and creatinine in dried plasma spots through liquid chromatography-tandem mass spectrometry. Vancomycin demonstrated excellent linearity within the range 3–50 µg/mL, while creatinine exhibited linearity from 1 to 70 µg/mL (both with <i>r</i>² &gt; 0.995). The trueness of all compounds was maintained within ± 15%, the precision was less than 15%, and the recoveries were within acceptable boundaries. Moreover, no significant matrix effects were detected. By employing the Passing–Bablok and Bland–Altman methods, we compared the differences and consistencies between the wet plasma concentrations and dried plasma spot concentrations of vancomycin and creatinine in 71 samples. The results revealed no significant distinctions between the two approaches and showcased comparable consistencies, implying that the dried plasma spots technique can be effectively utilized for the simultaneous determination of vancomycin and creatinine in plasma.</p>\u0000 </div>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":"48 10","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}