Journal of Surgical Research最新文献

{"title":"Cover 1: Update","authors":"","doi":"10.1016/S0022-4804(24)00693-0","DOIUrl":"10.1016/S0022-4804(24)00693-0","url":null,"abstract":"","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"303 ","pages":"Page OFC"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142700009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"JOURNAL OF SURGICAL RESEARCH","authors":"","doi":"10.1016/S0022-4804(24)00733-9","DOIUrl":"10.1016/S0022-4804(24)00733-9","url":null,"abstract":"","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"303 ","pages":"Pages iv-x"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142700007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AASF-Fall-2024-JSR-Ad-November-Issue","authors":"","doi":"10.1016/S0022-4804(24)00729-7","DOIUrl":"10.1016/S0022-4804(24)00729-7","url":null,"abstract":"","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"303 ","pages":"Page IFC"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142700051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sequential Fasciotomies for Managing Abdominal Compartment Syndrome: Porcine Experimental Study","authors":"Javier Lopez-Monclus MD, PhD, FACS ,&nbsp;Amparo Gómez-Cruz MD, PhD ,&nbsp;Joaquin M. Munoz-Rodriguez MD, PhD, FACS ,&nbsp;Sandra Catalina García-Perrote MD ,&nbsp;Laura Román García de León MD ,&nbsp;Luis A. Blazquez-Hernando MD, PhD ,&nbsp;Álvaro Robin Valle De Lersundi MD, PhD ,&nbsp;Martin Santos-González DVM, PhD ,&nbsp;José Luis Lucena de la Poza MD, PhD ,&nbsp;Miguel A. Garcia-Urena MD, PhD, FACS","doi":"10.1016/j.jss.2024.09.072","DOIUrl":"10.1016/j.jss.2024.09.072","url":null,"abstract":"<div><h3>Introduction</h3><div>Abdominal compartment syndrome (ACS) poses a significant clinical challenge, with high morbidity and mortality rates. Conventional treatment via decompressive laparotomy with open abdomen and temporary closure presents significant drawbacks. This experimental study evaluates the efficacy of open minimally invasive sequential fasciotomy in managing simulated ACS in a porcine model.</div></div><div><h3>Methods</h3><div>Ten adult pigs were included in this prospective experimental investigation, wherein a mechanical model of abdominal hypertension was induced by pneumoperitoneum via a Veres needle. Open minimally invasive sequential fasciotomy, involving bilateral external oblique muscles (EOMs) and <em>linea alba (LA)</em>, was performed. Physiological parameters were recorded preprocedure and postprocedure.</div></div><div><h3>Results</h3><div>In our study, 70% of pigs completed the fasciotomy sequence. Unilateral EOM fasciotomy significantly reduced intravesical pressure and femoral venous pressure by 18% and 16%, respectively. Bilateral EOM fasciotomies led to a 35.7% decrease in both parameters. Following re-establishment of intra-abdominal pressure to 20 mmHg, <em>LA</em> fasciotomy resulted in a 47% drop in intravesical pressure and femoral venous pressure. Significant increases in tidal volume and abdominal perimeter were observed after each fasciotomy.</div></div><div><h3>Conclusions</h3><div>This study establishes that open minimally invasive sequential fasciotomy of bilateral EOM and <em>LA</em> is an effective strategy for managing simulated ACS in a porcine model. Each fasciotomy resulted in a significant reduction in intra-abdominal pressure. These findings suggest that sequential fasciotomy techniques offer a promising alternative to decompressive laparotomy in ACS management. Further research is essential to validate these outcomes in human subjects.</div></div>","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"303 ","pages":"Pages 761-771"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142546106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vascular Graft Infections Treated With Bioabsorbable Antibiotic Beads","authors":"Aaron Litvak BA ,&nbsp;Joshua T. Geiger MD ,&nbsp;Joel Kruger MD ,&nbsp;Benjamin Ford MD ,&nbsp;Roan Glocker MD, MPH ,&nbsp;Michael Stoner MD","doi":"10.1016/j.jss.2024.09.079","DOIUrl":"10.1016/j.jss.2024.09.079","url":null,"abstract":"<div><h3>Introduction</h3><div>Inguinal vascular surgical site infections (VSSI) and infected prosthetic grafts remain a critical problem in vascular surgery. Prior clinical reports suggest antibiotic-impregnated beads may be used to attempt salvage of the graft and improve outcomes, especially if explant would result in major amputation or mortality. Described is our institutional experience managing inguinal VSSI using bioabsorbable, antibiotic-impregnated beads compared to inguinal VSSI managed with debridement alone.</div></div><div><h3>Methods</h3><div>Patients with VSSIs after lower-extremity procedures were identified through the institutional database and departmental registries from 2014 to 2023. Cases were excluded if they did not involve an inguinal wound infection or an operation for VSSI management. Outcomes, including amputation-free survival, reinfection, and re-operation for infection were recorded, along with microbial isolates. Basic descriptive statistics, Kaplan–Meier, and Multiple variable Cox proportional hazards analyses were performed.</div></div><div><h3>Results</h3><div>There were 43 patients identified (23 with intravenous antibiotics and debridement alone, and 20 treated with intravenous antibiotics, debridement, and antibiotic beads). The two groups differed significantly in their Szilagyi classification, with thirteen patients (65%) with class III infections in the antibiotic bead group compared with one (7%) in the debridement alone group. There was no significant difference in amputation-free survival for those cases that received debridement and antibiotic beads <em>versus</em> debridement alone (<em>P</em> = 0.20) or amputation-free survival between Szilagyi classifications (<em>P</em> = 0.47) despite a higher representation of Szilagyi III cases in the antibiotic bead group (<em>P</em> = 0.0001). Patients with graft infections treated with beads experienced similar survival outcomes to patients with subcutaneous infections treated with debridement alone (<em>P</em> = 0.21).</div></div><div><h3>Conclusions</h3><div>The efficacy of bioabsorbable antibiotic beads in VSSIs remains controversial. While this cohort study demonstrated an increased risk of re-infection, this is confounded by the antibiotic bead group having a higher frequency of graft infections. Antibiotic beads appear to be safe for use in patients with vascular graft infections and may help achieve outcomes comparable to patients without graft involvement. Further studies with larger patient populations and similar infection severity between groups are needed.</div></div>","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"303 ","pages":"Pages 772-779"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142546107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter Regarding: Physicians Are Unable to Consistently Predict Patient Health Literacy in a Breast Clinic.","authors":"Barry D Weiss","doi":"10.1016/j.jss.2024.07.127","DOIUrl":"10.1016/j.jss.2024.07.127","url":null,"abstract":"","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":" ","pages":"795"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142348993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response Regarding: Digital Ink and Surgical Dreams: Perceptions of Artificial Intelligence-Generated Essays in Residency Applications.","authors":"Loralai M Crawford, Justine Lam, Lisa M Cannon, Yanjie Qi, Lauren DeCaporale-Ryan, Nicole A Wilson","doi":"10.1016/j.jss.2024.09.033","DOIUrl":"10.1016/j.jss.2024.09.033","url":null,"abstract":"","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":" ","pages":"799-800"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142468420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Journal of Surgical Research","authors":"","doi":"10.1016/S0022-4804(24)00696-6","DOIUrl":"10.1016/S0022-4804(24)00696-6","url":null,"abstract":"","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"303 ","pages":"Page iii"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142700006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ASC 2025 Save the Date Journal Ad","authors":"","doi":"10.1016/S0022-4804(24)00734-0","DOIUrl":"10.1016/S0022-4804(24)00734-0","url":null,"abstract":"","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"303 ","pages":"Page xii"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142700010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Higher Doses of Calcium Associated With Survival in Trauma Patients","authors":"Dillon J. Wade MD ,&nbsp;Collin Pilkington BS ,&nbsp;J. Curran Henson MD, MS ,&nbsp;Hanna K. Jensen MD, PhD ,&nbsp;Kyle Kalkwarf MD ,&nbsp;Avi Bhavaraju MD ,&nbsp;Nolan Bruce MD ,&nbsp;Stephen Bowman PhD ,&nbsp;Joseph Margolick MD","doi":"10.1016/j.jss.2024.02.014","DOIUrl":"10.1016/j.jss.2024.02.014","url":null,"abstract":"<div><h3>Introduction</h3><div><span>Calcium is required for coagulation, cardiac output, and peripheral vascular resistance<span><span>. Between 85% and 94% of trauma patients treated with massive </span>blood transfusion develop hypocalcemia.</span></span>¹ The aim of this study is to evaluate the relationship between increased intravenous calcium administration during massive transfusion and improved survival of trauma patients.</div></div><div><h3>Methods</h3><div><span>We performed a retrospective analysis of trauma patients who received massive transfusion over a 2-y period. Doses of elemental calcium administered per unit of blood product transfused were calculated by calcium to blood product ratio (CBR). Chi-square test evaluated association between coagulopathy and 30-d mortality. Two-sample </span><em>t</em><span><span>-test evaluated association between CBR and coagulopathy. Bivariate regression analysis evaluated association between CBR and blood products transfused per patient. Multivariable </span>logistic regression analysis<span>, controlling for age, sex, coagulopathy, and Injury Severity Score evaluated the association between CBR and mortality.</span></span></div></div><div><h3>Results</h3><div>The study included 77 patients. Coagulopathy was associated with increased 30-d mortality (<em>P</em> &lt; 0.05). Patients who survived had higher CBR than those who died (<em>P</em> &lt; 0.05). CBR was associated with a significant reduction in total blood products transfused per patient (<em>P</em> &lt; 0.05). CBR was not associated with coagulopathy (<em>P</em> = 0.24). Multivariable logistic regression analysis demonstrated that Injury Severity Score ≥16, coagulopathy and decreased CBR were significant predictors of mortality (<em>P</em> &lt; 0.05). CBR above 50 mg was a predictor of survival (<em>P</em> &lt; 0.05).</div></div><div><h3>Conclusions</h3><div>Higher doses of calcium given per blood product transfused were associated with improved 30-d survival and decreased blood product transfusions.</div></div>","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"303 ","pages":"Pages 788-794"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140189888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}