{"title":"Journal of Surgical Research","authors":"","doi":"10.1016/S0022-4804(25)00599-2","DOIUrl":"10.1016/S0022-4804(25)00599-2","url":null,"abstract":"","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"314 ","pages":"Page iii"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145219609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter Regarding: Surgical Resection of a Single Colorectal Lung Metastasis is Associated With Best Survival","authors":"Tom Treasure MD, Fergus Macbeth DM","doi":"10.1016/j.jss.2025.06.085","DOIUrl":"10.1016/j.jss.2025.06.085","url":null,"abstract":"","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"314 ","pages":"Pages 722-724"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144765041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter Regarding: Patients' Surgical History Profile and Its Association With Complexity in Major Emergency Abdominal Surgery","authors":"Moein Ashouri MD, Seyed Amirhossein Hosseini MD","doi":"10.1016/j.jss.2025.06.092","DOIUrl":"10.1016/j.jss.2025.06.092","url":null,"abstract":"","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"314 ","pages":"Pages 727-728"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144794794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexandra M P Brito, Leah C Tatebe, Castigliano M Bhamidipati, Francis X Guyette, Stephen R Wisinewski, James F Luther, Jason L Sperry, Martin A Schreiber
{"title":"Pragmatic Early Predictors of Survival After Trauma.","authors":"Alexandra M P Brito, Leah C Tatebe, Castigliano M Bhamidipati, Francis X Guyette, Stephen R Wisinewski, James F Luther, Jason L Sperry, Martin A Schreiber","doi":"10.1016/j.jss.2025.07.017","DOIUrl":"10.1016/j.jss.2025.07.017","url":null,"abstract":"<p><strong>Introduction: </strong>Accurately predicting the risk of early mortality after trauma can guide appropriate use of resources. This study aims to create a pragmatic mortality prediction from prehospital data.</p><p><strong>Methods: </strong>The Linking Investigators in Trauma and Emergency Service Task Order One (LITES TO1) database was used to identify predictors of mortality at hour 3, hour 24, and day 30 after trauma. Individual characteristics were assessed using a bivariate logistic regression model. The independent effect of characteristics significantly associated with mortality in a bivariate setting were assessed using a machine learning recursive partitioning model.</p><p><strong>Results: </strong>Initial Glasgow Coma Scale motor score (GCSm) and worst GCS were the strongest predictors of mortality at all time points. Both were predictive of all three most common causes of death: traumatic brain injury/herniation, prehospital/traumatic arrest, and uncontrolled hemorrhage.</p><p><strong>Conclusions: </strong>This is the first predictive machine-learned model tot demonstrate that initial prehospital GSCm strongly predicts mortality after trauma. Using this measure as indication for transport to trauma-designated hospitals could improve resource allocation.</p>","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"314 ","pages":"245-254"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144804307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jake L. Cotton MD , Adnan Syed BS , Danielle Abbitt MD , Andrew Mecum BA , Chiagoziem Anigbogu BA , Teresa S. Jones MD , Muhammad Aftab MD , Jessica Y. Rove MD , Edward L. Jones MD
{"title":"Cost of Veteran Coronary Artery Bypass Grafting: Veterans Health Administration Versus Community Care","authors":"Jake L. Cotton MD , Adnan Syed BS , Danielle Abbitt MD , Andrew Mecum BA , Chiagoziem Anigbogu BA , Teresa S. Jones MD , Muhammad Aftab MD , Jessica Y. Rove MD , Edward L. Jones MD","doi":"10.1016/j.jss.2025.09.001","DOIUrl":"10.1016/j.jss.2025.09.001","url":null,"abstract":"<div><h3>Introduction</h3><div>The community care program within the Veterans Health Administration (VHA) funds veteran care in the community. Cost of this program has increased with limited comparisons between VHA and community care hospitals. We seek to compare differences in cost of coronary artery bypass grafting (CABG) between VHA and community care hospitals.</div></div><div><h3>Methods</h3><div>We perform a retrospective cohort review of veterans undergoing CABG between October 1, 2018, and September 30, 2020, within VHA and community care hospitals within Veteran Integrated Service Network 19. Cost of index hospitalization was measured using VHA databases.</div></div><div><h3>Results</h3><div>Three hundred sixty-one veterans met final inclusion criteria at a total of 37 hospitals. One hundred ninety-five (54%) underwent surgery within the VHA and 166 (46%) underwent surgery in the community. CABG performed within the VHA were similar in cost to community (VHA median [interquartile range]: $122,213 [$80,829-$162,586] <em>versus</em> community: $112,923 [$74,797-$154,729]; <em>P</em> = 0.23), despite a longer postoperative length of stay. When controlling for other factors including hospital length of stay with a log gamma model, VHA performed CABG were less expensive than community (<em>P</em> = 0.007). There was no difference in index hospitalization metrics and 30-d outcomes.</div></div><div><h3>Conclusions</h3><div>CABG within the VHA is lower cost than community care after controlling for other factors. Continuous evaluation of community care cost is necessary to ensure efficient use of funding and program sustainability.</div></div>","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"315 ","pages":"Pages 145-150"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145213087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad Al Ma'ani, Francisco Castillo Diaz, Muhammad Haris Khurshid, Omar Hejazi, Tanya Anand, Audrey L Spencer, Collin Stewart, Anastasia Kunac, Louis J Magnotti, Bellal Joseph
{"title":"Silence of the Brittle: The Role of Frailty in Pain Perception and Management in Geriatric Trauma Patients.","authors":"Mohammad Al Ma'ani, Francisco Castillo Diaz, Muhammad Haris Khurshid, Omar Hejazi, Tanya Anand, Audrey L Spencer, Collin Stewart, Anastasia Kunac, Louis J Magnotti, Bellal Joseph","doi":"10.1016/j.jss.2025.06.079","DOIUrl":"10.1016/j.jss.2025.06.079","url":null,"abstract":"<p><strong>Introduction: </strong>Pain management in geriatric trauma patients is linked to improved quality of life and better outcomes. However, the role of patient-related factors in pain perception and management is unknown. The aim of our study is to assess whether frailty is associated with differences in daily pain scores and analgesic use among geriatric trauma patients.</p><p><strong>Methods: </strong>We performed a 2-y (2021-2022) analysis of geriatric database at our level I trauma center. We included all geriatric (≥65 y) patients admitted to our trauma service with normal neurological exam and length of stay >48 h. Patients were stratified using the trauma-specific frailty index into frail (F) and nonfrail (NF) groups. Daily pain scores (10-point numeric scale), the highest reported pain score during the admission, regional and systemic analgesia received in the first 7 d, and overall analgesic requirements were recorded and compared. Analgesics were converted to morphine milligram equivalents. Descriptive statistics and multivariable linear regression analyses, adjusting for potential confounding factors were performed.</p><p><strong>Results: </strong>We identified a total of 275 geriatric trauma patients (NF 167, F 108). The mean age was 78 (8) y and 52% were male. The median injury severity score was 9 [4-10], with 93% sustaining blunt injuries. There were no significant differences in terms of patients' demographic and injury characteristics between F and NF groups. On univariate analysis, the F group were less likely to report pain and had significantly lower opioid morphine milligram equivalent requirements in the first week of admission and overall. On linear regression analysis, frailty was independently associated with lower average pain scores in the first week (β = -1.81, 95% confidence interval [CI] [-3.51 to -0.11], P = 0.038), lower overall highest pain scores (β = -0.97, 95% CI [-1.64 to -0.302], P = 0.05), and received less opioids per day in the first week (β = -10.63, 95% CI [-16.55 to -4.71], P < 0.001) and overall (β = -15.02, 95% CI [-22.81 to -7.24], P < 0.001). Subanalysis of patients substratified by injury severity score showed similar trends.</p><p><strong>Conclusions: </strong>Frailty was associated with lower reported pain scores and reduced opioid use, regardless of injury severity. Whether these discrepancies are owing to differences in pain perception by patients or under-reporting it to health-care providers is yet to be understood. These findings lay the foundation for further research to explore the role of frailty on the pathophysiology of pain in geriatric trauma patients.</p>","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"314 ","pages":"291-297"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144817029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"On The Cover","authors":"","doi":"10.1016/S0022-4804(25)00601-8","DOIUrl":"10.1016/S0022-4804(25)00601-8","url":null,"abstract":"","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"314 ","pages":"Page xi"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145219611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marina Levochkina, Carter Colwell, Taneen Maghsoudi, Katie Bower, Tonja Locklear, Maxine Lee, Michael Saccocci, Hunter Sharp, Joshua Stodghill
{"title":"Should We Utilize Regional Anesthesia for Traumatic Rib Fracture Patients? A TQIP-Based Study.","authors":"Marina Levochkina, Carter Colwell, Taneen Maghsoudi, Katie Bower, Tonja Locklear, Maxine Lee, Michael Saccocci, Hunter Sharp, Joshua Stodghill","doi":"10.1016/j.jss.2025.06.091","DOIUrl":"10.1016/j.jss.2025.06.091","url":null,"abstract":"<p><strong>Introduction: </strong>Rib fractures are a common injury in trauma patients and can lead to pneumonia, respiratory failure, and mortality. Multimodal analgesia, alone or with regional anesthetic (epidural or local block), is a mainstay in management. Single-institution studies have evaluated the effectiveness of regional anesthesia with varied results. This study utilized national trauma registry (Trauma Quality Improvement Program [TQIP]) data to evaluate the association between regional anesthesia and mortality, as well as secondary outcomes of hospital complications and ventilator/intensive care unit (ICU)/hospital length of stay (HLOS).</p><p><strong>Materials and methods: </strong>Utilizing TQIP data from 2021, all patients with isolated chest trauma were identified. Data collected included demographic, medical comorbidities, injury severity, type of injury, hospital complications, ventilator/ICU/HLOS, and in-hospital mortality. Patients were categorized as those receiving regional anesthesia (epidural or peripheral nerve block) or no regional anesthesia. Propensity matching was performed, and outcomes were compared.</p><p><strong>Results: </strong>After propensity matching, 1295 patients were included in each group. There was no significant difference in in-hospital mortality between the two groups. Increased HLOS, ICU admissions, unplanned intubations, and unplanned upgrade to the ICU were associated with regional anesthesia. There were no other significant differences in outcomes between the two groups.</p><p><strong>Conclusions: </strong>A review of TQIP data did not detect a difference in mortality with regional anesthesia for rib fracture management. Rather, regional anesthesia was associated with increased HLOS, ICU admissions, unplanned intubations, and unplanned upgrade to the ICU. Further study is warranted to assess if subsets of patients might benefit from these procedures.</p>","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"314 ","pages":"273-283"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144804308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Scott Eldredge MD, Lois W. Sayrs PhD, David M. Notrica MD
{"title":"Response Regarding: Prior Emergency Department Utilization and Nonaccidental Trauma in Children","authors":"R. Scott Eldredge MD, Lois W. Sayrs PhD, David M. Notrica MD","doi":"10.1016/j.jss.2025.06.045","DOIUrl":"10.1016/j.jss.2025.06.045","url":null,"abstract":"","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"314 ","pages":"Pages 716-717"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}