Risk Factors for Surgical Site Infections Following Achilles Tendon Rupture Surgery: A Systematic Review and Meta-Analysis

IF 1.7 3区医学 Q2 SURGERY

Journal of Surgical Research Pub Date : 2025-09-18 DOI:10.1016/j.jss.2025.07.054

Yuxiang Zhou MM , Ming Zhong MM , Jianfeng Long MM , Gang Zhou BD , Xiaobing Luo MM , Qiang Zhang MM

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引用次数: 0

Abstract

Introduction

The Achilles tendon is most susceptible to rupture in the lower extremity during exercise. For patients with high requirements for Achilles tendon function, surgery is the preferred method. However, surgical site infections (SSIs) significantly affect functional prognosis and increase the medical burden. This meta-analysis identified risk factors for SSIs in patients with Achilles tendon rupture (ATR).

Methods

We systematically searched Embase, PubMed, Cochrane Library, CNKI (China National Knowledge Infrastructure), Web of Science, VIP (VIP Database for Chinese Technical Periodicals), Wanfang Data, and SinoMed up to October 2024 for studies comparing SSI and non-SSI patients with ATR. Study quality was assessed using the Newcastle–Ottawa Scale. Odds ratios (OR) and 95% confidence intervals were calculated for potential risk factors, and STATA 17.1 was used for analysis.

Results

Nineteen studies were included. Smoking (OR = 2.39), diabetes (OR = 2.18), open wounds (OR = 11.95), and season (autumn and winter) of injury (OR = 3.00) were identified as significant risk factors for SSIs. Male (OR = 0.55), acute ATR (OR = 0.22), and antibiotic use (OR = 0.31) were identified as protective factors against SSIs.

Conclusions

This study highlights key risk factors for SSIs following ATR surgery, aiding clinicians in identifying high-risk patients and implementing targeted interventions.

查看原文本刊更多论文

跟腱断裂手术后手术部位感染的危险因素：系统回顾和荟萃分析。

运动时，下肢跟腱最容易断裂。对于对跟腱功能要求较高的患者，手术是首选方法。然而，手术部位感染（ssi）显著影响功能预后并增加医疗负担。本荟萃分析确定了跟腱断裂（ATR）患者发生ssi的危险因素。方法：系统检索Embase、PubMed、Cochrane Library、CNKI、Web of Science、VIP（中文技术期刊VIP数据库）、万方数据和中国医学信息网，检索截止到2024年10月SSI和非SSI患者与ATR的比较研究。使用纽卡斯尔-渥太华量表评估研究质量。计算潜在危险因素的优势比（OR）和95%置信区间，使用STATA 17.1进行分析。结果：共纳入19项研究。吸烟（OR = 2.39）、糖尿病（OR = 2.18）、开放性伤口（OR = 11.95）和损伤季节（秋季和冬季）（OR = 3.00）被认为是ssi的重要危险因素。男性（OR = 0.55）、急性ATR （OR = 0.22）和抗生素使用（OR = 0.31）被确定为预防ssi的保护因素。结论：本研究强调了ATR手术后ssi的关键危险因素，有助于临床医生识别高危患者并实施有针对性的干预措施。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Surgical Research 医学-外科

CiteScore

3.90

自引率

4.50%

发文量

627

审稿时长

138 days

期刊介绍： The Journal of Surgical Research: Clinical and Laboratory Investigation publishes original articles concerned with clinical and laboratory investigations relevant to surgical practice and teaching. The journal emphasizes reports of clinical investigations or fundamental research bearing directly on surgical management that will be of general interest to a broad range of surgeons and surgical researchers. The articles presented need not have been the products of surgeons or of surgical laboratories. The Journal of Surgical Research also features review articles and special articles relating to educational, research, or social issues of interest to the academic surgical community.