Journal of science and medicine in sport最新文献

{"title":"Can we prepare young female players for heading in football? The feasibility and acceptability of HeaderPrep.","authors":"Andrew G Ross, Matthew Whalan, Rob Duffield, Kerry Peek","doi":"10.1016/j.jsams.2025.05.014","DOIUrl":"https://doi.org/10.1016/j.jsams.2025.05.014","url":null,"abstract":"<p><p>This study investigated the feasibility and acceptability of a novel programme designed to prepare players to learn heading in football (HeaderPrep). Forty-five players from four different girls' teams (under-11, under-12, under-13, under-15) and five coaches completed the programme over six weeks followed by completion of an evaluation survey. Our findings suggest that the programme enhanced players' confidence in heading the ball. Additionally, both players and coaches observed improvements in heading skill development. Most players (84.4%) also stated they would recommend HeaderPrep to others and found it fun. HeaderPrep may be a feasible introduction prior to starting formal heading training in football.</p>","PeriodicalId":16992,"journal":{"name":"Journal of science and medicine in sport","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of a personal health coaching intervention (dbcoach) on physical activity and glycated hemoglobin in patients with type 2 diabetes - A randomized controlled trial.","authors":"Vivien Hohberg, Eric Lichtenstein, Jan-Niklas Kreppke, Jan Kohl, Marc Donath, Fiona Streckmann, Markus Gerber, Lukas Zahner, Oliver Faude","doi":"10.1016/j.jsams.2025.05.013","DOIUrl":"https://doi.org/10.1016/j.jsams.2025.05.013","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to evaluate the effectiveness of the dbcoach intervention in improving key health outcomes in patients with type 2 diabetes.</p><p><strong>Design: </strong>The study employed a pragmatic randomized controlled trial with 100 participants randomly assigned to either an intervention group receiving 12 months of telephone-based coaching plus standard care, or a control group receiving standard care only.</p><p><strong>Methods: </strong>Primary outcomes were objectively measured moderate-to-vigorous physical activity and glycated hemoglobin, while secondary outcomes included further physical activity measures, diet, anthropometrics, medication, and quality of life. Data were collected at baseline as well as after 6 and 12 months. Linear mixed-effects models were employed for analysis.</p><p><strong>Results: </strong>The intervention improved moderate-to-vigorous physical activity (Cohen's d = 0.51; 95 % confidence interval: 0.11, 0.90) with an increase of 14.2 (95 % confidence interval: 3.0, 25.3) minutes per day. However, the effect on glycated hemoglobin was negligible (95 % confidence interval: -0.20; 0.32, -0.72). Sedentary behavior was decreased (Cohen's d = -0.20; -0.71, 0.31). Analysis of medication showed variability, with decreased use of total insulin (rate ratio = 0.82; confidence interval 0.50, 3.03), but higher overall diabetes medication in the intervention group. There were no differences in diet (Cohen's d = -0.12; 95 % confidence interval: -0.78, 0.53) and BMI (Cohen's d = 0.01; 95% confidence interval: -0.16, 0.15).</p><p><strong>Conclusions: </strong>The dbcoach intervention increased physical activity but did not impact glycated hemoglobin in type 2 diabetes patients. While the intervention can enhance physical activity, additional strategies may be necessary for glycemic control.</p>","PeriodicalId":16992,"journal":{"name":"Journal of science and medicine in sport","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A cross-sectional latent class analysis of self-reported snus use in men's and women's professional football in England.","authors":"Daniel Read, Ed Cope, Michael Bennett, Lee Taylor","doi":"10.1016/j.jsams.2025.05.008","DOIUrl":"https://doi.org/10.1016/j.jsams.2025.05.008","url":null,"abstract":"<p><strong>Objectives: </strong>Anecdotally, snus is widely used in Europe by professional footballers. However, prevalence and motivations for use have not been determined, alongside a lack of robust data regarding its use on player health and performance. The aims of the current research were to assess snus use amongst professional football players and categorise users through latent class analysis (LCA).</p><p><strong>Design: </strong>Mixed-method design involving a cross-sectional survey study of 628 male and 51 female professional footballers in England, and 16 semi-structured interviews with multidisciplinary football staff conducted during the 2023-24 season.</p><p><strong>Methods: </strong>The survey included self-reported questions concerning prevalence, motivations, sources, and perceived effects. Data were analysed using descriptive statistics and LCA to categorise players through their behaviours. Interview questions addressed perceived prevalence and behaviours, performance and health impacts, and support required. Interview data was analysed using mixed coding to contextualise quantitative analysis.</p><p><strong>Results: </strong>Overall, 18 % and 22 % of male and female footballers reported using snus, rising to 42 % and 39 % respectively for lifetime use. Snus use was initiated and motivated by a mix of factors including socialisation, boredom, relaxation, cravings, and stress management. Players were separated into three classes: occasional, daily, and habitual users demonstrating distinct profiles.</p><p><strong>Conclusions: </strong>Snus use appears commonplace in both men's and women's professional football, motivated by a complex set of personal and social factors. The identified types of snus users can inform personalised approaches to education and cessation interventions.</p>","PeriodicalId":16992,"journal":{"name":"Journal of science and medicine in sport","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144266473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of a classroom-based intervention to promote physical literacy in children: the randomized and controlled ALPHYL Study.","authors":"Jorge Romero-Martínez, Cristina Menescardi, Nuria Ortega-Benavent, Sergio Montalt-García, Lisa M Barnett, Xavier García-Massó, Isaac Estevan","doi":"10.1016/j.jsams.2025.05.006","DOIUrl":"https://doi.org/10.1016/j.jsams.2025.05.006","url":null,"abstract":"<p><strong>Objectives: </strong>Physically active learning and quality physical education can be an opportunity to increase physical activity and encourage its practice. Therefore, the study purpose was to analyze the effect of a classroom-based physical activity intervention on children's physical literacy, movement behavior and cognitive performance.</p><p><strong>Design: </strong>Randomized control trial (with retention) and multilevel linear model analysis.</p><p><strong>Methods: </strong>The Active Learning in Physical Literacy Study was conducted in Valencia (Spain) and involved 332 fifth grade students (10-11 years) from six primary schools (three experimental and three control). The intervention, registered at Clinicaltrials.gov (number NCT05812118), lasted 9-10 weeks and consisted of the implementation of three physically active learning activities for at least 30 min in combination with physical education lessons each day. The outcomes of the intervention were within movement behavior: moderate to vigorous physical activity; within physical literacy: perceived physical literacy, social support for physical activity, actual and perceived motor competence; and within cognitive performance: math fluency and teachers' proxy-report of math performance.</p><p><strong>Results: </strong>A significant interaction effect (group per time) on moderate to vigorous physical activity, actual motor competence, math fluency and teachers' proxy-report of math performance was found. No interaction effect was found in the psychosocial domain (perceived motor competence and physical literacy, and parent and peer support for physical activity).</p><p><strong>Conclusions: </strong>The Active Learning in Physical Literacy intervention was effective in enhancing movement behavior and cognitive performance. Therefore, movement-centered pedagogy enables the integration of physical activity with learning, which in turn contributes to improving elements of children's physical literacy.</p>","PeriodicalId":16992,"journal":{"name":"Journal of science and medicine in sport","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144225704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exercise and Sports Science Australia (ESSA) - Consensus Statement: Exercise blood pressure for the identification of uncontrolled hypertension: recommendations to support best-practice blood pressure management.","authors":"Martin G Schultz, Katharine D Currie, Kristofer Hedman, Andrew Maiorana, Rachel E Climie, Dianne Littlechild, Mark R Nelson, Jeff S Coombes, James E Sharman","doi":"10.1016/j.jsams.2025.05.011","DOIUrl":"https://doi.org/10.1016/j.jsams.2025.05.011","url":null,"abstract":"<p><strong>Objectives: </strong>High blood pressure (BP) affects >1 billion adults worldwide, with many cases undiagnosed and/or ineffectively controlled. There is a need for complementary approaches to that of in-clinic BP measurement at rest to identify uncontrolled high BP (≥140/90 mmHg). A hypertensive response to exercise (HRE) is associated with increased cardiovascular risk and likely represents poor BP control not detected via standard in-clinic BP at rest. Many clinical exercise professionals measure exercise BP as part of standard practice and are therefore uniquely placed to identify uncontrolled high BP from exercise BP. This statement was developed with the aim of providing exercise professionals with consensus and practical guidance to support best-practice BP management via the measurement of exercise BP.</p><p><strong>Design: </strong>Exercise and Sports Science Australia (ESSA) consensus statement.</p><p><strong>Methods: </strong>An international authorship team with research and clinical expertise covering exercise physiology, cardiology, blood pressure, and general practice was assembled to review evidence and develop a series of consensus recommendations.</p><p><strong>Results: </strong>Exercise BP measurement has significant potential to identify individuals with uncontrolled high BP. Exercise BP should be measured using best-practice technique during fixed workload exercise that elicits up to a moderate intensity (e.g., 64 < 76 % maximal heart rate). If an HRE is recorded (exercise systolic BP ≥170 mmHg), uncontrolled high BP should be assumed and trigger: 1) correspondence with a primary care physician (PCP) encouraging follow-up testing to ascertain BP status; 2) guidance for the patient to complete home BP measurement as part of ascertaining BP status and encouragement to report their findings to a PCP; and 3) with PCP confirmation of raised BP, ongoing exercise and lifestyle intervention to lower high BP.</p><p><strong>Conclusions: </strong>This consensus statement provides a recommended clinical pathway for clinical exercise professionals to utilise exercise BP measurement in practice and take a complementary role in the identification and management of high BP.</p>","PeriodicalId":16992,"journal":{"name":"Journal of science and medicine in sport","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144216129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Continuously monitoring runners' adaptive strategies to prolonged running on an outdoor track with straight and curved paths: Insights from the varying intersegment coordination variability and shock absorption during a full marathon.","authors":"Guoxin Zhang, Yihao Fu, Linjuan Wei, Fangbo Bing, Hejin Cai, Tony Lin-Wei Chen, Ming Zhang","doi":"10.1016/j.jsams.2025.05.012","DOIUrl":"https://doi.org/10.1016/j.jsams.2025.05.012","url":null,"abstract":"<p><strong>Objectives: </strong>This study investigated changes in lower limb intersegment coordination variability and impact shock in runners during a full marathon, whereas to assess how increasing mileage and track conditions (straight vs. curved paths) influenced these metrics in an outdoor environment.</p><p><strong>Design: </strong>A field-based observational study.</p><p><strong>Methods: </strong>Twenty-three amateur runners completed a self-paced marathon, during which inertial measurement units were used to collect segment kinematic data for computing coordination variabilities and impact shocks. Generalized estimating equations were employed to examine the effects of mileage (increments of 5 km) and track conditions (straight/curved) on the measures.</p><p><strong>Results: </strong>Runners exhibited increased coordination variabilities in sagittal planes and decreased coordination variabilities in non-sagittal planes as the race progressed. Significant changes were identified in coordination variabilities of shank vs. rearfoot at the later stages of the marathon (Wald χ² = 4.33-7.40, p = 0.007-0.037). All coordination variabilities were consistently lower on curved paths compared to straight paths with significant differences noted in the coupling of pelvis vs. thigh (Wald χ² = 24.25, p < 0.001). Tibial and pelvic impact shocks were elevated with increasing mileage after adjusting for running speed (Wald χ² = 21.99-36.17, p < 0.005).</p><p><strong>Conclusions: </strong>The runners showed distinct modulation of coordination variability across movement planes during prolonged running. Specifically, coordination variabilities were contained in non-sagittal planes while greater fluctuations were allowed in sagittal planes. These changes may compromise the norm of lower limb load attenuation, although further studies are warranted to explore their generalizability and the underlying mechanism.</p>","PeriodicalId":16992,"journal":{"name":"Journal of science and medicine in sport","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144225703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical fitness and cardiac function in childhood cancer survivors.","authors":"Pedro L Valenzuela, Javier S Morales, Elena Santana-Sosa, Blanca Herrero Velasco, Antonio Baño-Rodrigo, Eva S C Ramos, Alejandro Santos-Lozano, Alejandro Lucia, Carmen Fiuza-Luces","doi":"10.1016/j.jsams.2025.05.009","DOIUrl":"https://doi.org/10.1016/j.jsams.2025.05.009","url":null,"abstract":"<p><strong>Objectives: </strong>Childhood cancer treatment has long-term health sequelae but there is more controversy for physical fitness. We compared fitness and echocardiographic variables in childhood cancer survivors (CCSs) and controls. A secondary aim was to determine the potential role of previous enrollment in inpatient exercise, and of current physical activity (PA) levels.</p><p><strong>Design: </strong>Cross-sectional.</p><p><strong>Methods: </strong>CCSs (age = 5-18 yrs, ≥4 yrs since diagnosis) and controls (no cancer history) were recruited. Outcomes included anthropometric, cardiorespiratory fitness (CRF)-related variables, upper/lower-body muscle strength (5-repetition maximum), functional mobility (timed up and down stairs [TUDS] test), and echocardiography. We performed sub-analyses attending to previous enrollment in supervised exercise training during intensive treatment and current accelerometer-determined PA.</p><p><strong>Results: </strong>126 CCSs (12.8 ± 3.2 yrs, 41 % female) and 497 controls (11.2 ± 3.3 yrs, 40 % female) were studied. CCSs had a higher body mass index (+1.6 kg/m², p < 0.001). Despite no significant differences in peak oxygen uptake (-0.5 %, p = 0.900), CCSs had lower ventilatory threshold (-9.8 %, p = 0.018), strength (-42.9 to -52.2 % depending on the analyzed exercise, p < 0.001 for most exercises) and TUDS performance (-23 %, p < 0.001) values than controls. CCSs showed a higher prevalence of left-ventricle hypertrophy and concentric cardiac remodeling. These results were independent of inpatient exercise background. CCSs showed lower levels of moderate-to-vigorous PA (MVPA) and vigorous PA (VPA) (p < 0.005). In CCSs, a positive correlation was found between MVPA/VPA levels and CRF or strength-related variables (all r > 0.4, p < 0.05).</p><p><strong>Conclusions: </strong>CCSs showed impairments in some physical fitness and cardiac parameters ≥4 yrs posttreatment, which seemed independent of previous inpatient exercise background but not of MVPA/VPA levels after treatment.</p>","PeriodicalId":16992,"journal":{"name":"Journal of science and medicine in sport","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144225705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"The only way you're ever going to play sport again is if you go through surgery\": A mixed methods study exploring anterior cruciate ligament (ACL) injury treatment decisions from the perspective of 734 patients.","authors":"Stephanie R Filbay, Jane Rooney, Tammy Hoffmann, Zobaida Edib, Pek Ling Teo, Rana S Hinman, Kim L Bennell","doi":"10.1016/j.jsams.2025.05.010","DOIUrl":"https://doi.org/10.1016/j.jsams.2025.05.010","url":null,"abstract":"<p><strong>Objectives: </strong>In patients with anterior cruciate ligament injury, i) describe beliefs about treatment options and the information received from clinicians in different disciplines and ii) explore treatment decision-making experiences, including factors that influenced their treatment decisions.</p><p><strong>Design: </strong>Mixed-methods convergent parallel design, using an Australia-wide survey of 734 adults with anterior cruciate ligament injury, and 12 semi-structured interviews.</p><p><strong>Methods: </strong>Survey responses were reported descriptively. A phenomenological approach and inductive thematic analysis were used for qualitative analysis. Quantitative and qualitative data were analysed concurrently. An integration stage involved comparison and collation of findings.</p><p><strong>Results: </strong>Of 734 participants (70 % women), 540 (74 %) had anterior cruciate ligament reconstruction and 119 (16 %) were managed with rehabilitation alone. Participants consulted surgeons (94 %), physiotherapists (91 %), general practitioners (65 %), emergency department clinicians (22 %) and sports physicians (19 %). Most clinicians presented anterior cruciate ligament reconstruction as the best treatment [surgeons (85 %), physiotherapists (61 %)], and the best treatment to enable return to sport [surgeons (84 %), physiotherapists (62 %)]. Few clinicians informed patients that outcomes were similar on average between treatment strategies [surgeons (10 %), physiotherapists (29 %)]. Qualitative themes describe decision-making experiences: i) surgeons promoted surgery as the best/only option; ii) surgeon consults were rushed and patients felt poorly informed; iii) clinicians downplayed surgery risks and impacts; iv) general practitioners were utilised for referrals, not management advice; and v) mixed advice from physiotherapists. Quantitative and qualitative findings were closely aligned, with qualitative findings providing deeper insights into patients' treatment decision-making experience.</p><p><strong>Conclusions: </strong>Australians with anterior cruciate ligament rupture received mixed treatment advice from clinicians, who often portrayed surgery as the best treatment option. Some patients received an unbalanced overview of treatment options that did not reflect the best-available research evidence, inhibiting an informed treatment decision.</p>","PeriodicalId":16992,"journal":{"name":"Journal of science and medicine in sport","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144216207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Special Issue: Concussion and Head Impacts in Football (Call for Papers)","authors":"Tim Meyer","doi":"10.1016/j.jsams.2025.05.005","DOIUrl":"10.1016/j.jsams.2025.05.005","url":null,"abstract":"","PeriodicalId":16992,"journal":{"name":"Journal of science and medicine in sport","volume":"28 6","pages":"Pages 435-436"},"PeriodicalIF":3.0,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144090566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Variants within the MMP3 and COL5A1 genes associate with soft tissue injury history in elite male rugby athletes.","authors":"Jon Brazier, Mark R Antrobus, Peter C Callus, Adam J Herbert, Georgina K Stebbings, Daniel Martin, Stephen H Day, Liam P Kilduff, Mark A Bennett, Robert M Erskine, Stuart M Raleigh, Tom Cullen, Malcolm Collins, Yannis P Pitsiladis, Shane M Heffernan, Alun G Williams","doi":"10.1016/j.jsams.2025.05.007","DOIUrl":"https://doi.org/10.1016/j.jsams.2025.05.007","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate associations between genetic variants within COLGALT1, COL1A1, COL3A1, COL5A1, KDR, MIR608, MMP3, NID1, TIMP2 and VEGFA and injury history in elite male rugby athletes.</p><p><strong>Design: </strong>A case-control genetic association study was conducted on 184 elite male rugby athletes.</p><p><strong>Methods: </strong>Participants were genotyped for 13 genetic polymorphisms previously associated with soft tissue injury using standard PCR assays. Injury data were collected via a self-reported injury-history questionnaire. Single-locus association and Total Genotype Score (TGS) analyses were conducted using χ² tests. In addition, multifactor dimensionality reduction and inferred haplotype analysis were used to identify genetic interactions.</p><p><strong>Results: </strong>The TT genotype of MMP3 rs679620 was underrepresented in the non-injured ligament group compared to the ligament sprain and ligament rupture groups (10 %, 32 %, 25 %; P < 0.04, respectively). The T allele of MMP3 rs679620 was overrepresented in the non-injured tendon group compared to the tendinopathy group (50 %, 38 %; P < 0.02). The proportion of C allele carriers of COL5A1 rs12722 was higher in the tendon rupture group than the non-injured tendon group (96 %, 75 %; P < 0.02). Furthermore, the T-C inferred haplotype frequency of COL5A1 rs12722 and COL5A1 rs3196378 was higher in the tendon rupture, ligament sprain and total injured athlete groups compared to their respective non-injured groups (P < 0.02).</p><p><strong>Conclusions: </strong>This study is the first to identify associations between MMP3 rs679620 and COL5A1 rs12722 and soft-tissue injury history in elite male rugby athletes. These findings support the growing evidence that soft-tissue injury could be influenced by an athlete's genetic predisposition.</p>","PeriodicalId":16992,"journal":{"name":"Journal of science and medicine in sport","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144225706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}