Medicinska istrazivanja最新文献_第9页

The Institute of Histology and Embryology in the most modern building of the Faculty of Medicine in Belgrade between two worlds wars 组织学和胚胎学研究所位于两次世界大战期间贝尔格莱德医学院最现代化的建筑中

Medicinska istrazivanja Pub Date : 1900-01-01 DOI: 10.5937/medi56-44482

N. Puškaš

{"title":"The Institute of Histology and Embryology in the most modern building of the Faculty of Medicine in Belgrade between two worlds wars","authors":"N. Puškaš","doi":"10.5937/medi56-44482","DOIUrl":"https://doi.org/10.5937/medi56-44482","url":null,"abstract":"The Institute of Histology and Embryology was founded in 1921, but it was moved into its own building a few years later, in 1927. The project of the building was done by the architect Svetozar Jovanović, and the pedimental sculpture in the gable of the building was done by the academic sculptor Živojin Lukić. The building housed two institutes: the Institute of Physiology and the Institute of Histology. Each of the institutes owned one wing, and they shared the central part of the building, which also contained an amphitheater. The building was equipped with the most modern technical devices and provided excellent conditions for scientific work and teaching. In addition, within the Institute of Histology there were the Photography Department, the Terminology Department, the central catalog of the books and journals of the Faculty of Medicine, and a museum was planned as well The largest part of the building was destroyed in the German bombing on April 6, 1941. After liberation, according to the project of the architect Milan Sekulić, the reconstruction of the central part and the construction of new wings of the building were carried out.","PeriodicalId":167411,"journal":{"name":"Medicinska istrazivanja","volume":"107 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120909046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of social networks and mobile applications in physical activity during the COVID-19 epidemic in Serbia 塞尔维亚2019冠状病毒病疫情期间社交网络和移动应用程序在身体活动中的作用

Medicinska istrazivanja Pub Date : 1900-01-01 DOI: 10.5937/medi55-37524

N. Milic, Nikola Savić, Nina Rajovic, J. Milin-Lazović, Marko Savic, N. Milic, Petar Milčanović, Ksenija Marković, Tamara Stanisavljević, D. Nešić, S. Mazić

{"title":"The role of social networks and mobile applications in physical activity during the COVID-19 epidemic in Serbia","authors":"N. Milic, Nikola Savić, Nina Rajovic, J. Milin-Lazović, Marko Savic, N. Milic, Petar Milčanović, Ksenija Marković, Tamara Stanisavljević, D. Nešić, S. Mazić","doi":"10.5937/medi55-37524","DOIUrl":"https://doi.org/10.5937/medi55-37524","url":null,"abstract":"After the outbreak of the novel SARS-COV-2 coronavirus, in the Chinese province of Wuhan that spread rapidly across the world, the Government of the Republic of Serbia introduced protection measures in March 2020, to prevent the spread of the infectious disease COVID-19 in Serbia. All gatherings indoors (sport, cultural and other events), as well as in parks and public places intended for recreation and sports, were prohibited. Shortly after, a lockdown took place which prohibited leaving home with the exception of basic needs, work from home was recommended and online schooling was introduced. The World Health Organization has recommended the use of online resources to maintain basic physical activity. In these circumstances of social distancing, this study examines the prevalence of physical activity supported by social networks and mobile applications during the COVID-19 lockdown in Serbia. The study was conducted as a cross-sectional study, using questionnaire distributed through social networks. The study found that more than a third of respondents (38.3%) used social networks or mobile apps to perform physical activity during the lockdown in Serbia; 27.1% used social networks/mobile apps before the pandemic, while 11.2% began to use social networks/mobile apps to perform physical activity during the lockdown. Easy access and review of exercises were the most common reasons for using social networks/mobile apps. 40% of the participants in the study agreed that social networks/mobile apps, make it easier to engage in physical activity. Based on the presented results, it can be concluded that the promotion of physical activity at home through social networks and mobile apps can provide an invaluable contribution to maintaining physical activity globally during pandemics such as COVID-19.","PeriodicalId":167411,"journal":{"name":"Medicinska istrazivanja","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122015970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pediatric Radiotherapy Department: Recommendations for optimal infrastructure and personnel 儿科放射治疗科:最佳基础设施和人员的建议

Medicinska istrazivanja Pub Date : 1900-01-01 DOI: 10.5937/medist1801020n

M. Nikitović, D. Stanić

{"title":"Pediatric Radiotherapy Department: Recommendations for optimal infrastructure and personnel","authors":"M. Nikitović, D. Stanić","doi":"10.5937/medist1801020n","DOIUrl":"https://doi.org/10.5937/medist1801020n","url":null,"abstract":"In multidisciplinary treatment of malignant diseases in pediatric population, radiotherapy with or without surgery, represents the basic modality of local treatment. Although the basic principles of radiotherapy in children are the same as in adults, it has its own specificity because it is applied to an organism in the phase of growth and development. Also, pediatric tumors differ from tumors in adults, so pediatric radiation oncologist has to have knowledge of pediatric oncology. Treatment of children with malignant diseases requires coordinated work of a multidisciplinary team: radiation oncologist, pediatrician, various specialty surgeons, pathologists, each of whom participates in the decision making on combined oncological treatment. Treatment decisions are necessary made in a multidisciplinary environment with the necessary knowledge of all members of the pediatric oncology team. Pediatric radiation oncology has its specifics and requirements in terms of infrastructure and organization. The basic requirements apply to rooms, equipment, staff, and procedures. Based on the international recommendations, the necessary radiotherapy equipment and its number, for the work with children, is defined. In the treatment of children it is recommended to use 3D conformal radiotherapy, or other advanced techniques, in order to avoid the irradiation of healthy tissues as much as possible. Monitoring early and late unwanted effects of radiotherapy is of great importance in treating children with malignant tumors. Also, a certain level of knowledge in the pathology of malignant diseases of children is necessary of all the members of radiotherapy team. Pediatric radiotherapy, as an extremely sophisticated and complex method of treatment, can therefore only be performed in hospitals and centers that can meet all of the above high standards and recommendations with the coordinated work of a multidisciplinary team with experience in pediatric oncology.","PeriodicalId":167411,"journal":{"name":"Medicinska istrazivanja","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127100702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influence of metabolic parameters on LDL and HDL size and subclasses in adolescents with type 1 diabetes 代谢参数对青少年1型糖尿病患者LDL和HDL大小及亚类的影响

Medicinska istrazivanja Pub Date : 1900-01-01 DOI: 10.5937/medi55-37397

S. Kovačević, V. Zdravković, S. Đorđević, M. Ješić, A. Zeljković, D. Stanisavljević, Milica Vuković, Maja Ješić

{"title":"Influence of metabolic parameters on LDL and HDL size and subclasses in adolescents with type 1 diabetes","authors":"S. Kovačević, V. Zdravković, S. Đorđević, M. Ješić, A. Zeljković, D. Stanisavljević, Milica Vuković, Maja Ješić","doi":"10.5937/medi55-37397","DOIUrl":"https://doi.org/10.5937/medi55-37397","url":null,"abstract":"Alterations in the serum of low-density lipoprotein (LDL) and high-density lipoprotein (HDL) size and subclass contribute to the atherogenesis in coronary artery disease in diabetic patients. The purpose of this study is to evaluate the effect of metabolic parameters on LDL and HDL size and subclasses in adolescents with type 1 diabetes. The cross-sectional study included 43 adolescents (23 females, 20 males) with type 1 diabetes of mean age 15.09±1.94 years, with mean disease duration of 5.86 ± 3.08 years. LDL and HDL particles were separated by polyacrylamide gradient gel electrophoresis, while serum lipid parameters were determined by routine laboratory methods. Patients with inadequate metabolic control (HbA1c ≥ 7.5%) had a higher mean value of triglycerides (TG) (p = 0.041), higher proportions of small, dense LDL particles (p = 0.045), higher proportions of LDL IIA subclasses (p=0.03) and smaller LDL diameter (p = 0.02) and HDL diameter (p = 0.04) than patients with optimal metabolic control (HbA1c < 7.5%). Higher HbA1c and higher TG levels were statistically significantly related to small, dense LDL (r=0.341, p=0.025; r= 0.394, p= 0.009) and HDL particles (r=0.684, p=0.000; r=0.421, p=0.005). Predictors of small, dense LDL and HDL particles, which contribute to atherogenesis, were high HbA1c (HR = 1.52, 95% CI: 0.97-2.40; HR 3.87, 95% CI: 2.11-7.10) and elevated TG (HR= 1.10, 95% CI: 1.00-1.20; HR 1.85, 95% CI: 1.07-3.21). Diabetic adolescents require particular attention in order to minimize factors such as high HbA1c and elevated TGs in the development of future cardiovascular events.","PeriodicalId":167411,"journal":{"name":"Medicinska istrazivanja","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125147514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Tuberculosis: 60 years of systematic application of the vaccine Bacille Calmette Guerin in Serbia 结核病:塞尔维亚系统应用卡介苗60年

Medicinska istrazivanja Pub Date : 1900-01-01 DOI: 10.5937/medist1302021p

D. Pešut, E. Gvozdenović

引用次数: 0

Primary hepatic neuroblastoma in a 19-month-old child: A case report 19个月儿童原发性肝神经母细胞瘤1例报告

Medicinska istrazivanja Pub Date : 1900-01-01 DOI: 10.5937/medi55-28059

J. Dimić, D. Škorić, A. Sretenović, S. Đuričić

引用次数: 0

The role of leptin in regulation of neuronal activity associated with control of food intake 瘦素在调节与食物摄入控制相关的神经元活动中的作用

Medicinska istrazivanja Pub Date : 1900-01-01 DOI: 10.5937/medist1401036m

G. Marić, M. Labudović-Borović, Nada Tomanović, I. Zaletel, Marko Trtica, M. Lakočević, Milan Ćirić, Jelena Kostić, N. Puškaš

{"title":"The role of leptin in regulation of neuronal activity associated with control of food intake","authors":"G. Marić, M. Labudović-Borović, Nada Tomanović, I. Zaletel, Marko Trtica, M. Lakočević, Milan Ćirić, Jelena Kostić, N. Puškaš","doi":"10.5937/medist1401036m","DOIUrl":"https://doi.org/10.5937/medist1401036m","url":null,"abstract":"The process of eating is a set of complex and different forms of behavior. Its regulation is based up on appetite control and one of the important factors in that system is leptin, a peptide hormone primarily synthesized in the adipose tissue. Leptin levels, besides the amount of fat tissue in the body, depend on: food intake, sex, age, physical activity and glucose up-take. In addition, leptin secretion displays circadian rhythm. The effects of this hormone are mediated via leptin receptors, which are distributed in the central nervous system and several other tissues. Activation of the receptors initiates a cascade of several signaling pathways, of which JAK2/STAT3 is the most important pathway in the process of feeding regulation and energy homeostasis. Leptin controls energy balance and body weight by activating leptin receptors in the hypothalamus, and the arcuate nucleus of the hypothalamus is the main site of its action. Within that nucleus, leptin stimulates the activity of anorexigenic POMC/CART neurons and inhibits the activity of orexigenic AgRP/NPY neurons. In addition, leptin regulates the expression of (an)orexigenic neuropeptides in the ventromedial, paraventricular nucleus and in the lateral hypothalamus. Bearing these facts in mind, studies that were conducted have shown that leptin may have its place in the treatment of obesity, since its application leads to a significant reduction in body weight in animals and in people with a deficit of this hormone. This has led to the development of clinically appropriate product leptin, which has entered the third phase of clinical trial.","PeriodicalId":167411,"journal":{"name":"Medicinska istrazivanja","volume":"251 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132530317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metabolic syndrome and combined highly active antiretroviral therapy 代谢综合征和高活性抗逆转录病毒联合治疗

Medicinska istrazivanja Pub Date : 1900-01-01 DOI: 10.5937/medist1401024d

G. Dragović, Dragana Malovic, Đorđe Jevtović

引用次数: 0

A multidisciplinary approach to examing and treating panic disorder and dyspnea 多学科方法检查和治疗惊恐障碍和呼吸困难

Medicinska istrazivanja Pub Date : 1900-01-01 DOI: 10.5937/medist1401013l

M. Latas, B. Milenković

引用次数: 0

A modern approach to a geriatric patient: Half a century of geriatric medicine in Serbia 对老年病人的现代方法:塞尔维亚半个世纪的老年医学

Medicinska istrazivanja Pub Date : 1900-01-01 DOI: 10.5937/medist1401048d

N. Despotović, Živana Milićević, M. Davidović, N. Dimkovic, S. Dimković, Teodora Beljić-Živković, P. Erceg, D. Milosevic

引用次数: 0