Medicinska istrazivanja最新文献

Vitamin D and bronchial asthma 维生素D和支气管哮喘

Medicinska istrazivanja Pub Date : 1900-01-01 DOI: 10.5937/medist1503001d

S. Dimić-Janjić, B. Milenković

引用次数: 0

Leser-trelat sign in the diagnosis of occult neoplasms: Case report 隐匿性肿瘤的低侧征诊断1例

Medicinska istrazivanja Pub Date : 1900-01-01 DOI: 10.5937/medi55-37222

Vildana Jahić, Jagoda Balaban, Đuka Ninković-Baroš, D. Lukic, D. Jović, Andrea Stanojević, B. Pavlovska

引用次数: 0

Subacute sclerosing panencephalitis: Changes in phenotype during the last decade 亚急性硬化性全脑炎:近十年来表型的变化

Medicinska istrazivanja Pub Date : 1900-01-01 DOI: 10.5937/medi55-41280

R. Kravljanac, Ilija Palić, Biljana Vučetić-Tadić

{"title":"Subacute sclerosing panencephalitis: Changes in phenotype during the last decade","authors":"R. Kravljanac, Ilija Palić, Biljana Vučetić-Tadić","doi":"10.5937/medi55-41280","DOIUrl":"https://doi.org/10.5937/medi55-41280","url":null,"abstract":"Introduction: Subacute sclerosing panencephalitis (SSPE) is a rare, progressive, neurodegenerative disease with poor outcome. Anti-measles vaccination contributed to a decreasing number of SSPE patients, but not to its eradication. The aim of our study is to evaluate the course of the disease in our SSPE patients with a focus on vaccinated children. The main goal is considering possibilities for improving prevention of the disease. Methods: A retrospective study included the patients with SSPE treated in the period from December 2010 to December 2020 at the Pediatric Clinic of the Institute. The inclusion criteria were the patients with the diagnosis of SSPE based on clinical presentation, neuroimaging, electroencephalography and positive IgG anti-measles antibodies, both in serum and CSF. Results: Five children with fulminant course of SSPE were included. All these patients were suffering from measles at an early age. Three of them had been vaccinated against measles and two had not. All of them had previously been healthy, immune-competent children, with normal general development. The course was extremely fulminant with lethal outcome within three months since the initial symptoms in four cases. Progressive motor and cognitive decline, behavior changes, movement disorders, myoclonic jerks and seizures were dominant in clinical presentation. Conclusion: Despite vaccination, SSPE has not been eradicated. An increasing number of vaccinated immune-competent children with fulminant form of SSPE and history of measles infection at an early age were treated at our Clinic. As a measure for improving prevention, we suggest considering weaning of vaccine-derived immunity, and re-vaccination of girls at reproductive period.","PeriodicalId":167411,"journal":{"name":"Medicinska istrazivanja","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125313043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The influence of bacterial infections on the course and outcome of patients with liver cirrhosis: Prophylaxis and treatment 细菌感染对肝硬化患者病程和转归的影响:预防和治疗

Medicinska istrazivanja Pub Date : 1900-01-01 DOI: 10.5937/medist1703001m

Tamara Milovanovic, V. Nikolic

{"title":"The influence of bacterial infections on the course and outcome of patients with liver cirrhosis: Prophylaxis and treatment","authors":"Tamara Milovanovic, V. Nikolic","doi":"10.5937/medist1703001m","DOIUrl":"https://doi.org/10.5937/medist1703001m","url":null,"abstract":"Bacterial infections in liver cirrhosis are very common and currently represent one of the most important causes of progression of liver disease, repeated hospitalizations and leading cause of death. The incidence of bacterial infections is 4-5 times higher in patients with cirrhosis compared to the general population, while mortality is 3.75 times higher in patients who develop bacterial infection. Spontaneous bacterial peritonitis, urinary infection, pneumonia, skin and soft tissue infections, and bacteremia are the most common bacterial infections, and E. coli, Klebsiella pneumoniae and Enterobacteriaceae are among the most common causes of these. In recent years, research has shown that increasingly frequent bacterial infections are present in patients with cirrhosis of multi-drug resistant bacteria (MDRs) such as Enterobacteriaceae extended spectrum that produce b-lactamase (ESBL), non-fermentable gram negative bacilli such as Pseudomonas aeruginosa , Stenotrophomonas maltophilia, Acinetobacter baumanii, Meticillin-resistant Staphylococcus aureus (MRSA), Vancomycin-sensitive or resistant Enterococci (VSE, VRE). Recent studies have shown that there is an increasing prevalence of resistance to the most frequently used antibiotics in patients with cirrhosis of the liver, such as Norfloxacin and the third generation Cephalosporin, and therefore an early antibiotic treatment with adequate antibiotics is of crucial importance.","PeriodicalId":167411,"journal":{"name":"Medicinska istrazivanja","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125586953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Supervisor education and quality of PhD studies: Current status and future challenges 博士生导师教育与质量:现状与未来挑战

Medicinska istrazivanja Pub Date : 1900-01-01 DOI: 10.5937/medi55-40099

P. Milovanović, Tatjana Pekmezović

{"title":"Supervisor education and quality of PhD studies: Current status and future challenges","authors":"P. Milovanović, Tatjana Pekmezović","doi":"10.5937/medi55-40099","DOIUrl":"https://doi.org/10.5937/medi55-40099","url":null,"abstract":"Supervision is a specific relationship, where an experienced senior researcher provides guidance, support, and advice to navigate a junior colleague through the barriers to becoming an independent researcher. While supervision is clearly a rewarding duty, it is also associated with a number of challenges. It is clear that supervision involves many responsibilities, which means that the supervisor needs to possess a certain set of skills. While many of these skills are learned in the direct interaction with PhD candidates, it would be beneficial if a more formal and structured training was offered to supervisors, especially at the beginning of their supervision careers, so as to avoid frequent mistakes in the supervisor-PhD candidate relationship. Hence, the idea is to shift from experience-based supervision to professionalization, believing that such an approach would reduce the risk of poor supervision. At present, many universities offer formal education of supervisors. The practice of organized education of supervisors at University of Belgrade Faculty of Medicine started in 2019 with the aim of preparing future supervisors to establish productive and responsive relationships with PhD candidates. After a break due to the COVID-19 pandemic, a revised supervision course was organized in 2022. The survey conducted among the attendees of the two organized courses supported the need for better education of university teachers in terms of supervision skills and leading of PhD candidates. Indeed, considering the fact that PhD outcomes are largely dependent on the supervisor and the successful supervisor-PhD candidate relationship, supporting supervision through formal training and education may be an important step in improving PhD experience and outcomes for both supervisors and PhD candidates.","PeriodicalId":167411,"journal":{"name":"Medicinska istrazivanja","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126755075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Neuroteology: The link between science and religion 神经学:科学与宗教之间的联系

Medicinska istrazivanja Pub Date : 1900-01-01 DOI: 10.5937/medist1602044d

A. Damjanović, Viktorija Popović, Aleksandra Damjanović

引用次数: 0

The beginnings and the restoration of the Institute of Medical Physiology of the Faculty of Medicine University of Belgrade through the work and character of its restorer Professor Milutin Nešković 通过米卢廷教授Nešković的工作和特点，贝尔格莱德大学医学院医学生理学研究所的成立和恢复

Medicinska istrazivanja Pub Date : 1900-01-01 DOI: 10.5937/medi56-44450

Dragana M. Đurić

{"title":"The beginnings and the restoration of the Institute of Medical Physiology of the Faculty of Medicine University of Belgrade through the work and character of its restorer Professor Milutin Nešković","authors":"Dragana M. Đurić","doi":"10.5937/medi56-44450","DOIUrl":"https://doi.org/10.5937/medi56-44450","url":null,"abstract":"With the passage of time and the lack of quality archival materials, both at the Institute and at the Faculty of Medicine and bearing in mind the \"culture of memory\", the work on this text, which is a continuation of the work on the published monograph on the occasion of the 100th anniversary of the establishment of the Institute of Medical Physiology of the Faculty of Medicine of the University of Belgrade and the beginning of classes, was an extremely challenging undertaking. The texts previously published by fellow teachers in faculty publications on various anniversaries, as well as in the \"Serbian Archive\" journal, significantly helped the realization of this undertaking. The willingness and kindness in providing important historiographical material, documents and photographs, by the family members of Professor Richard A. Burian from the USA (Richard M. Burian, Jim Huntington), Milutin Nešković from France and Belgrade (Nenad and Nikola Nešković, respectively) and Božidar Nikolić (Emilija Nikolić Đorić) should be appreciated, and then by numerous colleagues from our country, including Vojislav Voki Kostić, son of the famous professors Aleksandar Đ. Kostić and Smilja Joksić-Kostić. I owe everyone a big thank you, because they made it possible to systematize these important data. However, I am aware that this will not be a complete text, which primarily dealt with the beginnings of work and the restoration of the Institute, and with an exceptional professor and patriot, Prof. Dr. Milutin Nešković, the restorer of the destroyed Institute after the end of the Second World War, whose personality and work, as well as the strength of character, can be a role model for future generations of teachers and associates.","PeriodicalId":167411,"journal":{"name":"Medicinska istrazivanja","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122436136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pathological elongations of the carotid arteries: Diagnostics and surgical treatment 颈动脉病理性延长:诊断和手术治疗

Medicinska istrazivanja Pub Date : 1900-01-01 DOI: 10.5937/medist1302043s

S. Stanić, V. Sotirović, S. Tanasković, N. Aleksić, Đ. Radak

{"title":"Pathological elongations of the carotid arteries: Diagnostics and surgical treatment","authors":"S. Stanić, V. Sotirović, S. Tanasković, N. Aleksić, Đ. Radak","doi":"10.5937/medist1302043s","DOIUrl":"https://doi.org/10.5937/medist1302043s","url":null,"abstract":"Pathological elongations of cervical blood vessels are relatively common, but their exact incidence in general population is still unknown. The history of intermittent symptoms of cerebrovascular insufficiency, which may be provoked by rotatory movements of the head and the neck, should raise suspicion of the presence of carotid artery redundancy. On the basis of the clinical features and modern diagnostic procedures, we can determine the hemodynamic significance of kinking and coiling. Maximal systolic velocity, measured by color duplex ultrasonography, is an important parameter for reaching the diagnosis. Arteriography, CT or classic, is reserved only for symptomatic cases of kinking and coiling. Although the largest amount of morphological information is provided by intra-arterial digital subtraction arteriography, the number of surgical decisions made on the basis of non-invasive tests has increased. Surgical reconstruction in patients with hemodynamically significant kinking/coiling ICA is a safe and effective method of ischemic stroke prevention, which relieves the symptoms of cerebral ischemia and improves cerebral perfusion.","PeriodicalId":167411,"journal":{"name":"Medicinska istrazivanja","volume":"291 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114265824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tracheobronchial aspiration syndrome 气管支气管吸入综合征

Medicinska istrazivanja Pub Date : 1900-01-01 DOI: 10.5937/medist1701009p

D. Pesut, L. Nagorni-Obradović, V. Žugić, P. Minić, S. Popević, D. Marić

{"title":"Tracheobronchial aspiration syndrome","authors":"D. Pesut, L. Nagorni-Obradović, V. Žugić, P. Minić, S. Popević, D. Marić","doi":"10.5937/medist1701009p","DOIUrl":"https://doi.org/10.5937/medist1701009p","url":null,"abstract":"Aspiration-inhalation of solid or liquid materials into the airways-occurs when solids or liquids are introduced into the supraglottic area rapidly or in large volumes or when airway defences are reduced by structural abnormalities or neurological impairment. Tracheobronchial aspiration (TBA) syndrome is currently among leading causes of morbidity and mortality in the world when it comes to accidents, and it is the leading cause in one-year-old children. During the last several years, destructive effects of some food and drugs on respiratory system have been revealed. TBA may cause no complications at all or may result in a range of complications from paroxysmal cough to respiratory failure and lethal outcome. Rapid diagnosis is of utmost importance in correct interventions that should be done in a timely manner, and in prevention of complications, which are sometimes irreversible. This is a review of TBA syndrome etiopathogenesis with special reference to those caused by solid foreign bodies, including those of biological origin, hydrocarbons, lipids, and water-drowning. Special attention is given to TBA syndrome in children, and to complications such as aspiration pneumonia and pneumonitis. Current approach in treatment of the syndrome is explained in dependence of its etiology. Importance, indications and possibilities of interventional bronchoscopy are highlighted.","PeriodicalId":167411,"journal":{"name":"Medicinska istrazivanja","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116832244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Health literacy in the elderly 老年人的健康素养

Medicinska istrazivanja Pub Date : 1900-01-01 DOI: 10.5937/medist1803028b

Jelena Brcanski, A. Jovic-Vranes

引用次数: 0