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Journal of Parasitic Diseases最新文献

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Comparative evaluation of silver nanoparticles and human platelet rich-plasma versus traditional therapy in the treatment of murine chronic toxoplasmosis 纳米银颗粒和人血小板丰富血浆与传统疗法治疗小鼠慢性弓形虫病的比较评估
Journal of Parasitic Diseases Pub Date : 2024-03-01 DOI: 10.1007/s12639-023-01642-2
Shereen M. Ibrahim, A. Al-Ghandour, Sabah M. A. Mohamed, Heba H. M. Foaad, Enas S. El-Bahaie
{"title":"Comparative evaluation of silver nanoparticles and human platelet rich-plasma versus traditional therapy in the treatment of murine chronic toxoplasmosis","authors":"Shereen M. Ibrahim, A. Al-Ghandour, Sabah M. A. Mohamed, Heba H. M. Foaad, Enas S. El-Bahaie","doi":"10.1007/s12639-023-01642-2","DOIUrl":"https://doi.org/10.1007/s12639-023-01642-2","url":null,"abstract":"","PeriodicalId":16664,"journal":{"name":"Journal of Parasitic Diseases","volume":"103 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140089233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antileishmanial effect of podophyllotoxin and podophyllin on Leishmania major in vitro and in vivo. podophyllotoxin 和 podophyllin 在体外和体内对大利什曼原虫的抗利什曼作用。
Journal of Parasitic Diseases Pub Date : 2024-03-01 Epub Date: 2024-02-25 DOI: 10.1007/s12639-024-01654-6
Amir Hossein Ghayour, Mahdi Delavari, Mohsen Arbabi
{"title":"Antileishmanial effect of podophyllotoxin and podophyllin on <i>Leishmania major</i> in vitro and in vivo.","authors":"Amir Hossein Ghayour, Mahdi Delavari, Mohsen Arbabi","doi":"10.1007/s12639-024-01654-6","DOIUrl":"10.1007/s12639-024-01654-6","url":null,"abstract":"<p><p>Therapeutic research is very important in the prevention and treatment of leishmaniasis due to problems such as drug resistance, scarring and disease recurrence. The aim of this study was to determine how <i>Leishmania major</i> responds to the anti-leishmaniasis properties of podophyllotoxin and podophyllin. Cultured Leishmania promastigotes were exposed to different concentrations of podophyllotoxin and podophyllin for 24 and 48 h. Then, during the animal phase, Balb/c mice were experimentally injected with Leishmania promastigotes. After wounding, the effects of 0.5% podophyllotoxin and 25% podophyllin on reducing wound diameter and the number of amastigotes in the wound were evaluated. Podophyllotoxin and podophyllin were 83% and 59% lethal to <i>Leishmania major</i> promastigotes at the highest concentrations (200 µg/ml) and time (48 h). In the in vivo study, the mean lesion diameter at the end of treatment in the negative control group was 15.10 mm compared to 14.21 mm and 11.55 mm in the 25% podophyllin and 0.5% podophyllotoxin groups, respectively. Although both agents reduced the size of mice wounds and the number of amastigotes in the wounds, podophyllotoxin was more effective in this regard. Based on the results, podophyllotoxin and podophyllin can be used as leishmaniasis drugs after further research.</p><p><strong>Graphical abstract: </strong></p>","PeriodicalId":16664,"journal":{"name":"Journal of Parasitic Diseases","volume":"48 1","pages":"157-162"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10908768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140028295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of larvicidal potential of Eritrean medicinal plants against Aedes aegypti. 评估厄立特里亚药用植物对埃及伊蚊的杀幼虫潜力。
Journal of Parasitic Diseases Pub Date : 2024-03-01 Epub Date: 2024-02-22 DOI: 10.1007/s12639-024-01653-7
Jeevan Jyoti Kaushik, Atul Kaushik, Dawit Mebrahtu, Efrem Bereket, Elen Eyob, Hana Kelifa, Kokob Weldemichael, Rahwa Andebrhan
{"title":"Evaluation of larvicidal potential of Eritrean medicinal plants against <i>Aedes aegypti</i>.","authors":"Jeevan Jyoti Kaushik, Atul Kaushik, Dawit Mebrahtu, Efrem Bereket, Elen Eyob, Hana Kelifa, Kokob Weldemichael, Rahwa Andebrhan","doi":"10.1007/s12639-024-01653-7","DOIUrl":"10.1007/s12639-024-01653-7","url":null,"abstract":"<p><p>Larvicidal activity of three Eritrean medicinal plants was evaluated against <i>Aedes aegypti</i> by conducting the bioassay using WHO methods. Efficacy of the plant extracts of <i>O. hadiense, R. officinalis</i> and <i>C. spinarum</i> was evaluated against 3rd instar <i>Aedes aegypti</i> larvae and mortality was recorded. LC<sub>50</sub> and LC<sub>90</sub> of the various plant extracts were also calculated using probit analysis. The morphological analysis of treated larvae was also performed. Extracts of <i>O. hadiense, C. spinarium</i> and <i>R. officinalis</i> were prepared using different solvents viz chloroform, 70% ethanol and water. Of the screened extracts, the chloroform extracts of <i>O. hadiense</i> exhibited the highest larvicidal activities and has the minimum LC<sub>50</sub> and LC<sub>90</sub> (24 mg/ml and 198.411 mg/ml respectively). Chloroform extract of <i>C. spinarium</i> exhibited the least larvicidal activity with maximum LC<sub>50</sub> and LC<sub>90</sub> (736.883 mg/ml and 1188.699 mg/ml respectively). Microscopic analysis confirmed the changes in the <i>Aedes aegypti</i> larvae caused by various plants extracts. An accumulation of dark pigmentation was observed in abdominal region and in the anal papillae after contact and also showed major structural damage such as destruction of the gut.</p>","PeriodicalId":16664,"journal":{"name":"Journal of Parasitic Diseases","volume":"48 1","pages":"150-156"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10908879/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140028296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nematocidal activity of chitosan nanoparticles conjugated with albendazole against the enteral and parenteral phases of trichinosis in experimentally infected mice. 与阿苯达唑共轭的壳聚糖纳米颗粒对实验感染小鼠肠道和肠外毛滴虫病的杀线虫活性。
Journal of Parasitic Diseases Pub Date : 2024-03-01 Epub Date: 2024-02-19 DOI: 10.1007/s12639-024-01648-4
Abeer A Mahgoub, Ragaa M Shoieb, Mohamed Sherif Negm, Hassan M Ibrahim, Shaimaa H El-Sayed, Mona M Khater
{"title":"Nematocidal activity of chitosan nanoparticles conjugated with albendazole against the enteral and parenteral phases of trichinosis in experimentally infected mice.","authors":"Abeer A Mahgoub, Ragaa M Shoieb, Mohamed Sherif Negm, Hassan M Ibrahim, Shaimaa H El-Sayed, Mona M Khater","doi":"10.1007/s12639-024-01648-4","DOIUrl":"10.1007/s12639-024-01648-4","url":null,"abstract":"<p><p>Trichinosis is a serious parasitic zoonotic disease caused mainly by <i>Trichinella spiralis.</i> The used drugs for treatment of trichinosis showed limited bioavailability and high degree of resistance. Moreover, they have a very poor effect in treatment of encysted larvae. Therefore, there is a need for development of new agents which help in improving the bioavailability of the used drugs and enable them to reach different tissues. This study was designed to assess the use of chitosan nanoparticles (CSNPs) in conjugation with full and half dose albendazole (ABZ) in treatment of intestinal and muscular trichinosis. Albino mice (84 mice) were used to evaluate the efficacy of drugs and divided into seven groups; I: control, II: ABZ (50 mg/kg) treated, III: ABZ (25 mg/kg) treated, IV: ABZ (50 mg/kg) conjugated CSNPs treated, V: ABZ (25 mg/kg) conjugated CSNPs treated, VI: CS treated and VII: CSNPs treated. Parasitological and histopathological examinations were used to evaluate the therapeutic efficacy of the used drugs. Results showed significant reduction of adult <i>Trichinella</i> extracted from intestine of all ABZ treated groups either conjugated or not with the highest reduction rate in group IV followed by group V with percentage of reduction of 99.33% and 98.11%, respectively and marked improvement of histopathological examination. Also, results showed significant reduction of <i>Trichinella</i> larvae extracted from muscles of group IV, V and VII with the highest reduction rate in group IV with percentage of reduction of 100% in muscle larvae and marked improvement of histopathological examination. It was concluded that albendazole full dose conjugated chitosan nanoparticles can be a good candidate drug for treating both intestinal and muscular trichinosis.</p>","PeriodicalId":16664,"journal":{"name":"Journal of Parasitic Diseases","volume":"48 1","pages":"141-149"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10909009/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140028298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: Anthelmintic and therapeutic effects of the biogenic zinc oxide nanoparticles against acute kidney injury induced by Parascaris equorum Infection in rats 更正：生物氧化锌纳米颗粒对大鼠马尾副蛔虫感染引起的急性肾损伤的驱虫和治疗作用
Journal of Parasitic Diseases Pub Date : 2024-02-15 DOI: 10.1007/s12639-024-01651-9
Sara Bayoumi Ali, Ayman Saber Mohamed, S. Fahmy, Manal El–Garhy, Mohamed R. Mousa, Fathy Abdel-Ghaffar
{"title":"Correction: Anthelmintic and therapeutic effects of the biogenic zinc oxide nanoparticles against acute kidney injury induced by Parascaris equorum Infection in rats","authors":"Sara Bayoumi Ali, Ayman Saber Mohamed, S. Fahmy, Manal El–Garhy, Mohamed R. Mousa, Fathy Abdel-Ghaffar","doi":"10.1007/s12639-024-01651-9","DOIUrl":"https://doi.org/10.1007/s12639-024-01651-9","url":null,"abstract":"","PeriodicalId":16664,"journal":{"name":"Journal of Parasitic Diseases","volume":"19 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139776089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: Anthelmintic and therapeutic effects of the biogenic zinc oxide nanoparticles against acute kidney injury induced by Parascaris equorum Infection in rats 更正：生物氧化锌纳米颗粒对大鼠马尾副蛔虫感染引起的急性肾损伤的驱虫和治疗作用
Journal of Parasitic Diseases Pub Date : 2024-02-15 DOI: 10.1007/s12639-024-01651-9
Sara Bayoumi Ali, Ayman Saber Mohamed, S. Fahmy, Manal El–Garhy, Mohamed R. Mousa, Fathy Abdel-Ghaffar
{"title":"Correction: Anthelmintic and therapeutic effects of the biogenic zinc oxide nanoparticles against acute kidney injury induced by Parascaris equorum Infection in rats","authors":"Sara Bayoumi Ali, Ayman Saber Mohamed, S. Fahmy, Manal El–Garhy, Mohamed R. Mousa, Fathy Abdel-Ghaffar","doi":"10.1007/s12639-024-01651-9","DOIUrl":"https://doi.org/10.1007/s12639-024-01651-9","url":null,"abstract":"","PeriodicalId":16664,"journal":{"name":"Journal of Parasitic Diseases","volume":"229 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139835763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gastrointestinal parasites of the wild ungulates (Mammalia: Cetartiodactyla) in the Hemis National Park, Ladakh, India 印度拉达克赫米斯国家公园野生有蹄类动物（哺乳纲：鲸目）的胃肠道寄生虫
Journal of Parasitic Diseases Pub Date : 2024-02-14 DOI: 10.1007/s12639-024-01652-8
Jigmet Zazay, Bilal A. Bhat, Hidayatullah Tak, Arif Nabi Lone
{"title":"Gastrointestinal parasites of the wild ungulates (Mammalia: Cetartiodactyla) in the Hemis National Park, Ladakh, India","authors":"Jigmet Zazay, Bilal A. Bhat, Hidayatullah Tak, Arif Nabi Lone","doi":"10.1007/s12639-024-01652-8","DOIUrl":"https://doi.org/10.1007/s12639-024-01652-8","url":null,"abstract":"","PeriodicalId":16664,"journal":{"name":"Journal of Parasitic Diseases","volume":"764 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139836942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gastrointestinal parasites of the wild ungulates (Mammalia: Cetartiodactyla) in the Hemis National Park, Ladakh, India 印度拉达克赫米斯国家公园野生有蹄类动物（哺乳纲：鲸目）的胃肠道寄生虫
Journal of Parasitic Diseases Pub Date : 2024-02-14 DOI: 10.1007/s12639-024-01652-8
Jigmet Zazay, Bilal A. Bhat, Hidayatullah Tak, Arif Nabi Lone
{"title":"Gastrointestinal parasites of the wild ungulates (Mammalia: Cetartiodactyla) in the Hemis National Park, Ladakh, India","authors":"Jigmet Zazay, Bilal A. Bhat, Hidayatullah Tak, Arif Nabi Lone","doi":"10.1007/s12639-024-01652-8","DOIUrl":"https://doi.org/10.1007/s12639-024-01652-8","url":null,"abstract":"","PeriodicalId":16664,"journal":{"name":"Journal of Parasitic Diseases","volume":"8 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139777207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ovicidal, larvicidal and adulticidal activity of black pepper (Piper nigrum L.) essential oil and tea tree oil (Melaleuca alternifolia) against Haemonchus contortus 黑胡椒（Piper nigrum L.）精油和茶树油（Melaleuca alternifolia）对线虫的杀卵、杀幼虫和杀成虫活性
Journal of Parasitic Diseases Pub Date : 2024-02-13 DOI: 10.1007/s12639-024-01650-w
H. I. Mohamed, W. Arafa, Osama M. Ahmed, K. El-Dakhly
{"title":"Ovicidal, larvicidal and adulticidal activity of black pepper (Piper nigrum L.) essential oil and tea tree oil (Melaleuca alternifolia) against Haemonchus contortus","authors":"H. I. Mohamed, W. Arafa, Osama M. Ahmed, K. El-Dakhly","doi":"10.1007/s12639-024-01650-w","DOIUrl":"https://doi.org/10.1007/s12639-024-01650-w","url":null,"abstract":"","PeriodicalId":16664,"journal":{"name":"Journal of Parasitic Diseases","volume":"57 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139781475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ovicidal, larvicidal and adulticidal activity of black pepper (Piper nigrum L.) essential oil and tea tree oil (Melaleuca alternifolia) against Haemonchus contortus 黑胡椒（Piper nigrum L.）精油和茶树油（Melaleuca alternifolia）对线虫的杀卵、杀幼虫和杀成虫活性
Journal of Parasitic Diseases Pub Date : 2024-02-13 DOI: 10.1007/s12639-024-01650-w
H. I. Mohamed, W. Arafa, Osama M. Ahmed, K. El-Dakhly
{"title":"Ovicidal, larvicidal and adulticidal activity of black pepper (Piper nigrum L.) essential oil and tea tree oil (Melaleuca alternifolia) against Haemonchus contortus","authors":"H. I. Mohamed, W. Arafa, Osama M. Ahmed, K. El-Dakhly","doi":"10.1007/s12639-024-01650-w","DOIUrl":"https://doi.org/10.1007/s12639-024-01650-w","url":null,"abstract":"","PeriodicalId":16664,"journal":{"name":"Journal of Parasitic Diseases","volume":"409 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139841652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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