Journal of Occupational Health最新文献_第8页

Short-term economic evaluation of physical activity-based corporate health programs: a systematic review. 基于体育锻炼的企业健康计划的短期经济评估：系统回顾。

IF 2.6 4区医学

Journal of Occupational Health Pub Date : 2024-01-04 DOI: 10.1093/joccuh/uiae002

Lorenzo Bonatesta, Stefano Palermi, Felice Sirico, Mario Mancinelli, Pierpaolo Torelli, Ettore Russo, Giada Annarumma, Marco Vecchiato, Frederik Fernando, Giampietro Gregori, Josef Niebauer, Alessandro Biffi

{"title":"Short-term economic evaluation of physical activity-based corporate health programs: a systematic review.","authors":"Lorenzo Bonatesta, Stefano Palermi, Felice Sirico, Mario Mancinelli, Pierpaolo Torelli, Ettore Russo, Giada Annarumma, Marco Vecchiato, Frederik Fernando, Giampietro Gregori, Josef Niebauer, Alessandro Biffi","doi":"10.1093/joccuh/uiae002","DOIUrl":"10.1093/joccuh/uiae002","url":null,"abstract":"Objectives: Corporate health programs (CHPs) aim to improve employees' health through health promotion strategies at the workplace. Physical activity (PA) plays a crucial role in primary prevention, leading many companies to implement PA-based CHPs. However, there is limited examination in the scientific literature on whether PA-based CHPs (PA-CHPs) lead to economic benefits. This systematic review aimed to summarize the available literature on the economic aspects of PA-CHPs.Methods: A systematic review was conducted to identify studies focused on PA-CHPs targeting healthy sedentary workers and reporting at least one economic outcome, such as return on investment (ROI), costs, or sick leave.Results: Of 1036 studies identified by our search strategy, 11 studies involving 60 020 participants met the inclusion criteria. The mean (±SD) cost per capita for PA-CHPs was estimated as 359€ (±238€) (95% CI, 357-361€). In 75% of the studies, the net savings generated by PA-CHPs in 12 months were reported, with an average of 1095€ (±865€) (95% CI, 496-1690€). ROI was assessed in 50% of the included studies, with an average of 3.6 (±1.41) (95% CI, 2.19-5.01).Conclusions: In addition to promoting a healthy lifestyle, PA-CHPs have the potential to generate significant economic returns. However, the heterogeneity among the existing studies highlights the need for standardization and accurate reporting of costs in future research.","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10939391/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139106258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The relationship between air lead and blood lead in a modern US lead-acid battery facility: a longitudinal study. 美国一家现代化铅酸电池工厂的空气铅与血铅之间的关系：一项纵向研究。

IF 2.6 4区医学

Journal of Occupational Health Pub Date : 2024-01-04 DOI: 10.1093/joccuh/uiae073

Wenchao Li, Jiayang Chien, Joel M Cohen

{"title":"The relationship between air lead and blood lead in a modern US lead-acid battery facility: a longitudinal study.","authors":"Wenchao Li, Jiayang Chien, Joel M Cohen","doi":"10.1093/joccuh/uiae073","DOIUrl":"10.1093/joccuh/uiae073","url":null,"abstract":"Objectives: To date there has been little observational evidence on the relationship between air lead and blood lead at relatively low workplace air lead concentrations. This study sought to improve upon prior studies methodologically and aimed to examine this relationship in a modern workplace environment.Methods: Personal measurements of air lead and blood lead concentrations were collected in a modern lead-acid battery manufacturing facility in the United States. A total of 236 workers and their 2221 air-blood lead measurement pairs, collected between 2001 and 2021, were included in the statistical analysis. The association between air lead and blood lead was examined using linear mixed-effects models to account for data correlation. Potential confounders adjusted for included age, sex, job department, time trend, tenure, and seasonality.Results: The workers were mostly (83%) male and on average 29.75 years of age at the first included measurement. Their air lead concentrations ranged from 1 to 50 (arithmetic mean 16.85) μg/m3; blood lead concentrations ranged from 2 to 35 (arithmetic mean 15.47) μg/dL. After adjusting for potential confounders, a 1 μg/m3 increment in air lead was associated with a 0.025 (95% CI, 0.005-0.045; marginal, semi-partial ${R}^2$ = 0.002) μg/dL higher blood lead.Conclusions: The relationship between air lead and blood lead at relatively low workplace air lead concentrations over a long employment period may be very weak, but this needs to be further investigated in future observational studies with quantified lead exposures from noninhalation routes and nonoccupational sources.","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11742368/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142828430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on "Occupational health staff's involvement contributes to supervisor's perceived organizational support in Japanese workforce: a prospective cohort study". 关于 "日本劳动力中，职业健康人员的参与有助于主管感知组织支持：前瞻性队列研究"。

IF 2.6 4区医学

Journal of Occupational Health Pub Date : 2024-01-04 DOI: 10.1093/joccuh/uiae066

I Wayan Gede Suarjana

引用次数: 0

A systematic review of work-related health problems of factory workers in the textile and fashion industry. 纺织和时装业工厂工人与工作相关的健康问题系统回顾。

IF 2.6 4区医学

Journal of Occupational Health Pub Date : 2024-01-04 DOI: 10.1093/joccuh/uiae007

Raphael Kanyire Seidu, Emmanuel Abankwah Ofori, Benjamin Eghan, George Kwame Fobiri, Alex Osei Afriyie, Richard Acquaye

{"title":"A systematic review of work-related health problems of factory workers in the textile and fashion industry.","authors":"Raphael Kanyire Seidu, Emmanuel Abankwah Ofori, Benjamin Eghan, George Kwame Fobiri, Alex Osei Afriyie, Richard Acquaye","doi":"10.1093/joccuh/uiae007","DOIUrl":"10.1093/joccuh/uiae007","url":null,"abstract":"Objectives: The purpose of this study was to present a systematic review of the health-related problems of factory workers in the textile and fashion industry. These workers endure long sitting postures, poor workspace conditions, and long working hours to complete their overload of tasks. This situation results in several health problems that affect the productivity, mental health, and well-being of the workers.Methods: The relevant data (21 article publications) were obtained from the Scopus database. Analysis of the 21 articles was grouped under 3 research themes based on the critical reading of the content and abstracts: respiratory problems, musculoskeletal disorders, and psychological stressors and other health issues.Results: The findings show that factory workers are exposed to dust particles of cotton and other raw materials, fumes, and chemicals from manufacturing processes. This prolonged exposure without the use of personal protective equipment (PPE) leads to respiratory diseases like byssinosis that affect the workers' health. Additionally, working in a particular posture due to the workstation design for prolonged hours causes musculoskeletal disorders or pains. Workers also suffer from anxiety, depression, and stress from workload and pressure, hence making them unstable with reduced productivity.Conclusions: The findings of the study reinforce the need for a safe workspace and spacious work environment, provision of PPE, training in occupational hazards, frequent health checks, and ergonomic assessment of workstations to reduce prolonged work postures. Stakeholders, employers, policymakers, and governments should collaborate to safeguard and protect the well-being and health of the workers at these factories.","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10964409/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139642340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Global, regional, and national burden of cancers attributable to occupational risks from 1990 to 2019. 1990 年至 2019 年全球、地区和国家因职业风险造成的癌症负担。

IF 2.6 4区医学

Journal of Occupational Health Pub Date : 2024-01-04 DOI: 10.1093/joccuh/uiae040

Shiliang Ling, Lihong Zhou, Yanfeng Wu, Xiaoling Zhang, Wulong Han, Lihua Cui, Zhiyu Luan

{"title":"Global, regional, and national burden of cancers attributable to occupational risks from 1990 to 2019.","authors":"Shiliang Ling, Lihong Zhou, Yanfeng Wu, Xiaoling Zhang, Wulong Han, Lihua Cui, Zhiyu Luan","doi":"10.1093/joccuh/uiae040","DOIUrl":"10.1093/joccuh/uiae040","url":null,"abstract":"Background: Based on data from the Global Burden of Disease study, the burden of cancer attributable to occupational risks between 1990 and 2019 was explored.Methods: The estimated burden in different regions was compared in terms of the age-standardized death rates (ASDRs), age-standardized disability-adjusted life years (DALYs) rates, and corresponding estimated annual percentage changes (EAPCs). The comparative risk assessment framework was used to estimate the risk of death and DALYs attributable to occupational risk factors.Results: Globally from 1990 to 2019, ASDRs decreased (EAPC = -0.69; 95% CI: -0.76 to -0.61), and age-standardized DALY rates decreased (EAPC = -0.99; 95% CI: -1.05 to -0.94). In terms of the global age distribution of cancer attributable to occupational risk factors, the death rate and DALY rates increased with age. In addition, from 1990 to 2019, the number of deaths, DALYs, ASDRs, and age-standardized DALY rates in men were higher than those in women, and the cancer burden grew fastest in Georgia (EAPC = 5.04), Croatia (EAPC = 4.01), and Honduras (EAPC = 3.54). Moreover, as the sociodemographic index (SDI) value of a country or region increased, its burden of cancer attributable to occupational risk factors rapidly increased.Conclusions: The global cancer burden attributable to occupational risk factors declined from 1990 to 2019, was higher in men than in women, and was concentrated in middle-aged and older adults. The baseline cancer burdens of regions or countries increased as their SDI values increased and were especially high in high-SDI regions or countries.","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11378634/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141752011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of BMI changes in Japanese adults receiving face-to-face versus online counseling for specific health guidance: a noninferiority prospective observational study. 日本成年人在接受面对面与在线特定健康指导咨询后体重指数变化的比较：一项非劣效性前瞻性观察研究。

IF 2.6 4区医学

Journal of Occupational Health Pub Date : 2024-01-04 DOI: 10.1093/joccuh/uiae026

Satoru Kanamori, Kiyomi Tomiyama, Yasuo Haruyama

{"title":"Comparison of BMI changes in Japanese adults receiving face-to-face versus online counseling for specific health guidance: a noninferiority prospective observational study.","authors":"Satoru Kanamori, Kiyomi Tomiyama, Yasuo Haruyama","doi":"10.1093/joccuh/uiae026","DOIUrl":"10.1093/joccuh/uiae026","url":null,"abstract":"Objectives: This study aimed to evaluate the noninferiority of online counseling over face-to-face counseling for specific health guidance (SHG).Methods: This prospective observational study was conducted using specific health checkup (SHC) and SHG data of individuals with health insurance in Japan. We analyzed data from 1431 participants who met the inclusion criteria, including those who underwent online or face-to-face counseling between April 1, 2020 and March 31, 2021, and received an SHC in the following year but no earlier than 90 days after their first counseling session. Assessed variables comprised demographics, counseling methods, and SHC results, including baseline questionnaire findings and body mass index (BMI) at follow-up. We performed inverse probability of treatment weighting (IPTW) using propensity scores, with changes in BMI as the objective variable and the counseling method as the explanatory variable. We set the noninferiority margin to 0.175, based on a previous study.Results: The online and face-to-face counseling groups comprised 455 (31.8%) and 976 (68.2%) participants, respectively. The number of men and mean age were 214 (47.0%) and 49.9 years (SD: 6.9 years), respectively, in the online counseling group, and 491 (50.3%) and 51.1 years (SD: 7.6 years), respectively, in the face-to-face counseling group. IPTW using propensity scores revealed a regression coefficient of -0.014 (95% CI: -0.157 to 0.129) for the online group compared with the face-to-face group (P = .847). The CI was within the noninferiority margin.Conclusions: The effects of online counseling on BMI are likely noninferior to those of face-to-face counseling.","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11170213/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140903599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The individual and work-related factors associated with the occupational future time perspective: a cross-sectional study of older workers in Japan. 与职业未来时间视角相关的个人因素和工作相关因素：日本老年工人的横断面研究》。

IF 2.6 4区医学

Journal of Occupational Health Pub Date : 2024-01-04 DOI: 10.1093/joccuh/uiae032

Kosuke Sakai, Tomohisa Nagata, Takahiro Mori, Naozumi Sueyoshi, Shunsuke Inoue, Kiminori Odagami, Yoshiyuki Shibata, Koji Mori

{"title":"The individual and work-related factors associated with the occupational future time perspective: a cross-sectional study of older workers in Japan.","authors":"Kosuke Sakai, Tomohisa Nagata, Takahiro Mori, Naozumi Sueyoshi, Shunsuke Inoue, Kiminori Odagami, Yoshiyuki Shibata, Koji Mori","doi":"10.1093/joccuh/uiae032","DOIUrl":"10.1093/joccuh/uiae032","url":null,"abstract":"Objectives: Occupational future time perspective (OFTP) is important concept for a successful career in older workers. The purpose of this study was to examine the associations between individual and work-related factors and OFTP.Methods: We conducted a cross-sectional study via an online questionnaire survey. Respondents were stratified sampled according to the distribution of workers across Japan. To assess OFTP, we used the Japanese version of the OFTP scale. We included factors such as sex, age, education, marital status, subjective health status, personal income, length of employment, industry, size of company, employment status, working days per week, and night shift. Multiple regression analysis was employed to calculate the regression coefficients for each factor, with OFTP serving as the dependent variable.Results: In total we included 1484 respondents. Our findings indicated that higher OFTP was associated with higher education, better subjective health status, higher personal income, and smaller size of company. Compared with manufacturing, certain industries such as agriculture and forestry, transportation and postal services, and health care showed lower OFTP. In contrast to permanent workers, contract and part-time workers demonstrated lower OFTP, whereas owners of non-family businesses exhibited higher OFTP. Furthermore, individuals working 1-4 d/wk showed lower OFTP compared with those working 5 d/wk.Conclusions: Older workers facing limitations in resources, such as educational background, personal income, precarious employment, and health status, tend to have lower OFTP. Such individuals should be given priority for support and assistance.","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11360179/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141498308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A longitudinal study of rotating shift type and attention performance of acute and critical care nurses with chronotype as moderator variable. 以时间类型为调节变量，对急诊和重症监护护士的轮班类型和注意力表现进行纵向研究。

IF 2.6 4区医学

Journal of Occupational Health Pub Date : 2024-01-04 DOI: 10.1093/joccuh/uiae042

Ai Lee, Yen-Kuang Lin, Yu-Huei Lin, Wen-Pei Chang

{"title":"A longitudinal study of rotating shift type and attention performance of acute and critical care nurses with chronotype as moderator variable.","authors":"Ai Lee, Yen-Kuang Lin, Yu-Huei Lin, Wen-Pei Chang","doi":"10.1093/joccuh/uiae042","DOIUrl":"10.1093/joccuh/uiae042","url":null,"abstract":"Objectives: To investigate whether chronotype is a moderator variable that also interacts with shift type and whether they jointly influence the attention performance of nurses working in acute and critical care units.Methods: We adopted a longitudinal research design focusing on nurses working rotating shifts in the emergency room and intensive care units at a medical center. A total of 40 complete samples were obtained. Data analysis was conducted using the generalized estimating equations in SAS 9.4.Results: The mean (SD) age of the participants was 26.35 (2.12) years. After controlling for age, gender, and sleep duration, an interaction effect was discovered between a specific chronotype and shift type; that is, the interaction effect between chronotype and shift type was only significant when comparing late-types working the night shift with early- and intermediate-types working the night shift (B = -18.81, P = .011). The least squares means of the mean reaction time of the interaction effects between the 2 chronotype groups and the 3 shift types found that the mean reaction time of late-types working the night shift was 11.31 ms (P = .044) slower compared with working the day shift.Conclusions: The chronotype is a moderator variable between shift type and mean reaction time, such that matching the chronotype of nurses in acute and critical care units with the appropriate shift type improved their mean reaction time. It is hoped that the results of this study could serve as a reference for acute and critical care nurses when scheduling their shifts.","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11360591/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141748368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hierarchical clustering analysis of musculoskeletal stress factors and their risk level in cardboard manufacturing: research from PLIBEL. 纸板生产中肌肉骨骼压力因素及其风险程度的层次聚类分析：来自 PLIBEL 的研究。

IF 2.6 4区医学

Journal of Occupational Health Pub Date : 2024-01-04 DOI: 10.1093/joccuh/uiae008

Martha Roselia Contreras-Valenzuela, Carlos Alejandro Martínez-Ibanez

{"title":"Hierarchical clustering analysis of musculoskeletal stress factors and their risk level in cardboard manufacturing: research from PLIBEL.","authors":"Martha Roselia Contreras-Valenzuela, Carlos Alejandro Martínez-Ibanez","doi":"10.1093/joccuh/uiae008","DOIUrl":"10.1093/joccuh/uiae008","url":null,"abstract":"Objective: A hierarchical cluster analysis for the cardboard manufacturing industry was developed with the aim of identifying similarities between workstations in terms of musculoskeletal stress factors (MSFs) and their impact on workers' bodies.Methods: The hierarchical clustering analysis was conducted using data from 44 workstations, which included 6 body part divisions and 51 stress factors as variables with 36 answer options. Firstly, the content of the dataset was defined. Secondly, the data were agglomerated and classified into 3 clusters using Ward's method based on the presence or absence of stress factors. Finally, the multivariable matrix was reduced to 2 factors: the x-axis representing the risk level of the workstation, and the y-axis representing the impact on the workers' health.Results: The study found that workers' knees were the most affected body parts, with 47 cases. The resulting work-related musculoskeletal disorders included tendinitis, arthralgia, chondromalacia, and gonarthrosis. The MSF with the most significant impact on the body's health was fatiguing work that involves repeated jumps, prolonged squatting, or kneeling, present in cluster 1 and cluster 3. Moreover, two of the most common MSFs associated with repeated work positions were identified: a mild forward flexion of the back (63 cases) in combination with one leg being used more often to support the body (56 cases).Conclusions: It was possible to identify the main work-related musculoskeletal disorders and the associated stress factors for the cardboard manufacturing industry by using hierarchical cluster classification and analysis, enabling the classification of risk levels and the impact on body health for each workstation.","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11019563/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139746795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between relatively low blood lead levels and urinary δ-aminolevulinic acid concentrations among male workers at a Japanese battery factory. 日本一家电池厂男工相对较低的血铅含量与尿液中δ-氨基乙酰丙酸浓度之间的关系。

IF 2.6 4区医学

Journal of Occupational Health Pub Date : 2024-01-04 DOI: 10.1093/joccuh/uiae056

Kohei Hasegawa, Hirokazu Toubou, Masaru Mizuki, Teruomi Tsukahara, Tetsuo Nomiyama

{"title":"Association between relatively low blood lead levels and urinary δ-aminolevulinic acid concentrations among male workers at a Japanese battery factory.","authors":"Kohei Hasegawa, Hirokazu Toubou, Masaru Mizuki, Teruomi Tsukahara, Tetsuo Nomiyama","doi":"10.1093/joccuh/uiae056","DOIUrl":"10.1093/joccuh/uiae056","url":null,"abstract":"Objectives: Whether the known positive association between blood lead (PbB) levels and urinary δ-aminolevulinic acid (ALAU) also exists at relatively low PbB levels (<40 μg/dL) remains unclear. We aimed to investigate this association at lower PbB levels.Methods: We analyzed data from biannual medical examinations of workers at a Japanese factory from August 2013 to August 2023. We excluded records from female workers and those with missing data, resulting in a dataset consisting of 1396 records from 155 male workers. We employed mixed-effect linear regression models with a random intercept for workers and additional adjustments for age and smoking status.Results: The median PbB level across all the analyzed records was 8 μg/dL (range: 1-31 μg/dL). Significant positive associations were observed between PbB and ALAU, with a 1-unit increase in natural logarithm-transformed PbB corresponding to a 10.0% increase in ALAU (95% CI, 2.7%-17.9%). Categorized PbB analyses showed a 23.8% increase in ALAU (95% CI, 2.7%-49.2%) for PbB levels at 20-24 μg/dL and an 83.1% increase (95% CI, 30.1%-157.7%) for PbB levels ≥25 μg/dL, compared with those <5 μg/dL. The exposure-response curve analysis indicated a plateau followed by an increasing trend.Conclusions: A positive and nonlinear association between PbB and ALAU levels was observed at relatively low PbB levels.","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11472743/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142289567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0