Journal of Occupational Health最新文献

{"title":"Effectiveness of recommendations in promoting the use of mobile health applications in health guidance: a randomized controlled trial.","authors":"Takeshi Onoue, Kazuki Nishida, Yoshio Nakata, Fumi Hayashi, Miki Marutani, Naoki Sakane, Jiro Moriguchi, Shigeki Muto, Kiminori Kato, Izuru Masuda, Tomonori Okamura, Keiichi Matsuzaki, Takashi Kawamura, Kazuyo Tsushita","doi":"10.1093/joccuh/uiaf036","DOIUrl":"10.1093/joccuh/uiaf036","url":null,"abstract":"<p><strong>Objectives: </strong>Use of commercially available mobile health (mHealth) applications in supporting lifestyle improvements has become popular in recent years. However, the effectiveness of advice promoting the use of such applications based on individual behavioral goals in a health guidance setting remains unclear. This study explored how guiding participants of the Specific Health Guidance (SHG) program, a Japanese public health initiative to prevent cardiovascular disease, to use commercially available mHealth applications impacted their application usage, lifestyle habits, and cardiovascular risk factors.</p><p><strong>Methods: </strong>In this multicenter, randomized, open-label, parallel-group comparison study, 156 individuals with a history of SHG participation and who were engaged in the Motivational Health Guidance program (a type of SHG) in 2021 were assigned to intervention (n = 76) or control (n = 80) groups. Whereas both groups received standard guidance, the intervention group also received recommendations for mHealth applications based on their individual behavioral goals. The participants' application usage, behavioral changes, and body weight were assessed after 3 months, with health checkup data evaluated after 1 year.</p><p><strong>Results: </strong>The proportion of mHealth application users after 3 months was significantly higher in the intervention group (68.4%) than in the control group (40.0%). The intervention group also reported a significantly greater weekly frequency of mHealth application usage. Moreover, the intervention group reported a significantly decreased change in triglyceride levels after 1 year compared with the control group.</p><p><strong>Conclusions: </strong>Recommending commercially available mHealth applications in a health guidance setting significantly increased the number of mHealth application users and their frequency of use.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12321321/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144649714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Importance of early detection and treatment of occupational hypersensitivity pneumonitis.","authors":"Shinya Ohkouchi, Yasuo Morimoto, Narufumi Suganuma, Hajime Kurosawa, Kenichi Azuma, Hisamitsu Omori, Taro Tamura, Kunio Dobashi, Kengo Nakamoto, Makiko Nakano, Yuji Natori, Naomi Hisanaga, Kiyoshi Mizushima, Kazuhiro Yatera, Yasunari Miyazaki","doi":"10.1093/joccuh/uiaf026","DOIUrl":"10.1093/joccuh/uiaf026","url":null,"abstract":"<p><p>Recently, the incidence of pneumoconiosis has decreased due to strict dust control measures and environmental improvements in the workplace. The significance of other occupational diseases has relatively increased. Occupational hypersensitivity pneumonitis (OHP) is mainly caused by allergic reactions to antigens in the workplace. Therefore, the presence of subtle amounts of harmful substances in the environment can increase the risk of developing OHP. Not only organic substances but also inorganic substances can cause OHP. OHP is caused by a specific antibody reaction (type III allergy) or sensitized lymphocytes (type IV allergy) to a specific antigen. Based on the clinical course, OHP is classified into acute and chronic hypersensitivity pneumonitis (HP). Acute HP forms granulomas and is classified as a granulomatous lung disease (nonfibrotic HP), whereas chronic HP rarely forms granulomas and progresses to fibrosis (fibrotic HP). Differentiation between chronic HP and idiopathic or collagen vascular disease-related interstitial pneumonia is challenging. Additionally, the genetic background of each patient influences the onset, leading to diverse onset patterns. Antigens and modes of onset are diverse in the workplace. Therefore, diagnosis is difficult, and many patients may be misdiagnosed. Chronic HP with advanced fibrosis due to delayed antigen identification has a poor prognosis. This study aimed to present an overview of the causative antigens, diagnosis, prevention, and treatment of OHP to provide appropriate and timely medical attention.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12127028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Forest bathing improves inflammatory markers, SpO2, and subjective symptoms related to chronic obstructive pulmonary disease (COPD) in male subjects at risk of developing COPD.","authors":"Qing Li, Norimasa Takayama, Yukako Kimura, Hiroshi Takayama, Shigeyoshi Kumeda, Takashi Miura, Tsunemi Kitagawa, Yoichiro Aoyagi, Michiko Imai","doi":"10.1093/joccuh/uiaf041","DOIUrl":"10.1093/joccuh/uiaf041","url":null,"abstract":"<p><strong>Background: </strong>Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death worldwide, responsible for 3.5 million deaths in 2021. Effective preventive measures are needed. Forest bathing has been reported to have positive effects on the immune system. In addition, the clean air, mild climate, phytoncides, high oxygen concentration, and other elements of forests are expected to have benefits for respiratory diseases such as COPD. Based on the above background, this study used a randomized crossover design to examine the improving effects of forest bathing on inflammatory markers and subjective symptoms related to COPD.</p><p><strong>Methods: </strong>Thirty male subjects aged 63.1 ± 7.5 years were recruited after obtaining informed consent. These subjects participated in day trips to a Japanese cypress forest park and to a city area of Nagano Prefecture as a control in June 2024. Blood samples were taken in the afternoon of each day before and after the walks. Concentrations of α1-antitrypsin (α1-AT), C-reactive protein (CRP), fibrinogen, and interleukin 6 (IL-6) in blood were measured. Percutaneous oxygen saturation (SpO2), the profile of mood states (POMS), and questionnaires for subjective fatigue and respiratory symptoms and sleep quality were carried out before and after each trip.</p><p><strong>Results: </strong>Forest bathing significantly decreased the concentrations of blood CRP, α1-AT, IL-6, and fibrinogen, significantly increased SpO2, reduced subjective fatigue and respiratory symptoms, improved sleep and the scores of positive feelings, and reduced the scores for negative emotions in POMS.</p><p><strong>Conclusions: </strong>Forest bathing may improve inflammatory markers, SpO2, and subjective symptoms related to COPD.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12353587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144649715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mini-review: occupational health topics series on the effects of chemicals. Occupational cholangiocarcinoma incident.","authors":"Shinji Kumagai","doi":"10.1093/joccuh/uiaf001","DOIUrl":"10.1093/joccuh/uiaf001","url":null,"abstract":"<p><p>In 2012, a social issue arose concerning a high incidence of cholangiocarcinoma (bile duct cancer) among printing workers. The cause was prolonged exposure to high concentrations of 1,2-dichloropropane that was included in the ink cleaning agent. Until then, it was not known that this substance could cause cancer in humans. The author was involved in this incident from the beginning. This article describes the course from the start of the investigation to the recognition of cholangiocarcinoma as an occupational disease. Furthermore, the article presents the pathological characteristics of occupational cholangiocarcinoma, as well as epidemiological analysis results.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11830427/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relatively lower-intensity physical activity during leisure time and presenteeism among Japanese workers.","authors":"Koki Nagata, Shohei Yamamoto, Yosuke Inoue, Haruka Miyake, Hiroko Okazaki, Toshiaki Miyamoto, Takeshi Kochi, Isamu Kabe, Aki Tomizawa, Maki Konishi, Seitaro Dohi, Tetsuya Mizoue","doi":"10.1093/joccuh/uiaf037","DOIUrl":"10.1093/joccuh/uiaf037","url":null,"abstract":"<p><strong>Objectives: </strong>This study examines the cross-sectional association between relatively lower-intensity physical activity (LIPA) during leisure time and presenteeism, accounting for relatively higher-intensity physical activity (HIPA) during leisure time.</p><p><strong>Methods: </strong>Data were derived from 11 438 workers from 6 worksites of large companies in Japan, which participated in a questionnaire survey conducted between fiscal years 2018 and 2020. Frequency and duration per occasion were assessed for leisure-time physical activities at 3 intensities as determined by shortness of breath. LIPA was defined as activity not causing shortness of breath. The participants were divided into 3 groups according to LIPA volume (none, <60 min/wk, or ≥60 min/wk) and into 2 groups according to HIPA volume (none or engaged). A single question assessed the participants' presenteeism through self-ratings of their work performance. A multivariable Poisson regression model with a robust variance estimator estimated prevalence ratios (PRs) of presenteeism and their 95% CIs across the categories for both LIPA and HIPA.</p><p><strong>Results: </strong>The prevalence of presenteeism tended to decrease with increasing amounts of LIPA and HIPA (P for trend <.001). Among those who did not engage in HIPA, a significantly lower prevalence of presenteeism was observed among individuals who engaged in LIPA for ≥60 min/wk compared with those who did not (adjusted PR = 0.74; 95% CI = 0.68-0.81).</p><p><strong>Conclusions: </strong>This study supports the protective role of LIPA during leisure time that does not cause shortness of breath against presenteeism among workers who do not engage in HIPA during leisure time.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12303603/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144560442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuro-reproductive toxicity and carcinogenicity of 1-bromopropane: studies for evidence-based preventive medicine.","authors":"Gaku Ichihara","doi":"10.1093/joccuh/uiaf004","DOIUrl":"10.1093/joccuh/uiaf004","url":null,"abstract":"<p><p>Bromopropane was introduced commercially as an alternative to ozone-depleting and global-warming solvents. The identification of 1-bromopropane neurotoxicity in animal experiments was followed by reports of human cases of 1-bromopropane toxicity. In humans, the most common clinical features of 1-bromopropane neurotoxicity are decreased sensation, weakness in extremities, and walking difficulties. Moreover, decreased cognition, abnormal findings on brain magnetic resonance imaging, urinary incontinence, and numbness in the perineal area have also been described in workers exposed to 1-bromopropane. Murine histological studies showed that exposure to 1-bromopropane reduced the density of brain noradrenergic axons. Furthermore, proteome studies demonstrated 1-bromopropane-induced changes in the expression of proteins in the hippocampus of rats, similar to the changes seen in mice exposed to acrylamide, suggesting a common mechanism of electrophile-induced neurotoxicity. In addition to its neurotoxicity, 1-bromopropane also induces male reproductive toxicity in rats, although the targeted areas in the reproductive system differ from those affected by 2-bromopropane. However, exposure to high levels of 1-bromopropane was reported to induce spermatogenic cell degeneration, similar to that caused by 2-bromopropane, suggesting common mechanism(s) underlying 1- and 2-bromopropane-induced male reproductive toxicity. Plural approaches, including human, animal, and mechanistic studies, are useful for identification of 1-bromopropane neurotoxicity. The International Agency for Research on Cancer summarized that 1-bromopropane as well as 2-bromopropane share several key characteristics of carcinogens. Plural approaches can establish evidence-based preventive medicine by modification of the conventional evidence-based medicine (EBM), which has been developed for therapeutic medicine and is represented by the EBM pyramid.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11847597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Work tasks drive the physical behaviors of passenger train drivers.","authors":"Stephanie E Chappel, Anjum Naweed, Corneel Vandelanotte, Janine Chapman, Andreas Holtermann, Leon Straker","doi":"10.1093/joccuh/uiaf049","DOIUrl":"10.1093/joccuh/uiaf049","url":null,"abstract":"<p><strong>Objectives: </strong>Passenger rail drivers' physical behaviors contribute to individual, organizational, and community risks. As work tasks are theorized to determine physical behaviors performed during work hours, there is a need to clarify how work tasks determine passenger rail drivers' physical behaviors to inform improved work design. The aim of this study was to describe the physical behaviors of passenger train drivers across their work tasks and breaks, and explore what potential influences create variations in physical behaviors within tasks.</p><p><strong>Methods: </strong>An exploratory observational field study was conducted with passenger train drivers in South Australia. Across a shift drivers were observed directly, and a hierarchical task analysis was conducted to identify their main work tasks and sub-tasks, with simultaneous accelerometry to quantify the physical behaviors.</p><p><strong>Results: </strong>Ten male passenger train drivers, median age of 53 years, were observed. The hierarchical task analysis identified seven main tasks: Pre-Service, Set-Up, Driving, Switching Ends, Pack-Up, Waiting Time, and Breaks. Driving was almost all sitting (99%), whereas Set-Up and Switching Ends involved considerable moderate/vigorous physical activity (24% and 21%, respectively). Physical behaviors varied within tasks due to worker characteristics (eg, individual motivation), uncontrolled work elements (eg, weather), and structural work elements (eg, timetables).</p><p><strong>Conclusions: </strong>Passenger train drivers' physical behaviors at work were largely determined by their work tasks, but varied with worker characteristics, as well as uncontrolled and structural work elements. These findings may be used to inform future job redesigns to promote passenger train drivers' health through their physical behaviors at work.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12456960/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145030022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of work ability interventions on productivity: a systematic review.","authors":"Pasi Kekkonen, Eija Savolainen, Mari Immonen, Pauliina Kangas, Elisa Rissanen, Ismo Linnosmaa","doi":"10.1093/joccuh/uiaf051","DOIUrl":"10.1093/joccuh/uiaf051","url":null,"abstract":"<p><strong>Objectives: </strong>This systematic review aimed to synthesize the effectiveness of work ability interventions on productivity outcomes.</p><p><strong>Methods: </strong>This systematic review was registered in PROSPERO (CRD42024541404) and conducted in accordance with PRISMA guidelines. In December 2024, a systematic search from 2000 onward was conducted using databases including EBSCO, ProQuest, Scopus, Web of Science, and PubMed. Two reviewers independently screened articles, assessed quality using risk-of-bias tools, and extracted data, with a third reviewer resolving any disagreements. The eligibility criteria were defined using population, intervention, comparison, outcomes, and study design (PICOS) elements.</p><p><strong>Results: </strong>Of the 55 articles that underwent quality assessment, 26 were excluded due to high risk of bias. Among the remaining 29 articles, 24 were randomized controlled trials, of which 5 conducted economic evaluation, and 5 were nonrandomized controlled trials, collectively conducting 33 interventions. The results of the original studies showed that 5 work ability interventions had a statistically significant effect on productivity. Four interventions effectively reduced absenteeism, and 1 intervention increased the risk of absenteeism. One intervention indicated that the cost of absenteeism was reduced, and another showed that the intervention was more effective and less costly than usual occupational care.</p><p><strong>Conclusions: </strong>Our analysis of work ability interventions showed that 28 interventions did not have an effect on productivity and only 5 interventions affected productivity. This systematic review highlights the limited evidence regarding evidence-based work ability interventions that affect productivity. Despite the importance of the topic, it remains understudied, and there is insufficient evidence to support decision-makers aiming to enhance productivity.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490205/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep and well-being before and after a shift schedule change in ICU nurses: an observational study using wearable sensors.","authors":"Asami Ito-Masui, Ryota Sakamoto, Eiji Kawamoto, Eishi Motomura, Hisashi Tanii, Zachary D King, Kei Suzuki, Akane Sano, Motomu Shimaoka","doi":"10.1093/joccuh/uiaf053","DOIUrl":"10.1093/joccuh/uiaf053","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to evaluate, using wearable sensors, the impact of transitioning from an 8-hour to a 12-hour shift schedule on sleep patterns and well-being in intensive care unit (ICU) nurses with pre-existing sleep disturbances. We also examined differences in outcome based on chronotype.</p><p><strong>Methods: </strong>We conducted an observational study at a university hospital ICU between November 2020 and October 2023, before and after a hospital-wide shift schedule change. Nurses wore wearable sensors and completed daily surveys over 5 weeks under each shift system. Rotating-shift ICU nurses with a Pittsburgh Sleep Quality Index score >5 were eligible. Sleep metrics and subjective well-being were compared using linear mixed models, adjusting for age. Sleep episodes were categorized relative to shift timing, and chronotype-stratified subgroup analyses were performed.</p><p><strong>Results: </strong>Eighty nurses completed the study (12-hour shift: 37; 8-hour shift: 43). The interval between shifts was greater for the 12-hour shift group (36.12 vs 26.78 hours). Total sleep duration did not significantly differ between groups (12-hour shift: 418.5 minutes; 8-hour shift: 398 minutes); however, the 12-hour shift group had less fragmented sleep, higher subjective well-being scores, and lower reported stress and fatigue. Evening chronotypes appeared to benefit more from 12-hour shifts, with longer sleep duration and higher well-being scores, though these differences were not statistically significant.</p><p><strong>Conclusions: </strong>Transitioning to a 12-hour shift schedule was associated with reduced sleep fragmentation and improved well-being, particularly among evening chronotypes. These findings suggest that shift schedule structure and individual chronotype may influence adaptation to shift work in ICU settings.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12481240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145092057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of engineered nanomaterials on the cardiovascular system.","authors":"Sahoko Ichihara","doi":"10.1093/joccuh/uiae080","DOIUrl":"10.1093/joccuh/uiae080","url":null,"abstract":"<p><p>With the explosive development of nanotechnology, engineered nanomaterials are currently being used in various industries, including food and medicine. Concern about the health effects of nanomaterials has been raised, and available research indicates that the relative surface area of nanomaterials seems to correlate with the severity of their toxicity. With regard to engineered nanomaterials, the scope of their acute and chronic toxicities and their mechanisms are not fully understood. Studies suggest that exposure to certain nanomaterials can generate reactive oxidant species and enhance permeability of the phagolysosomal membrane, which leads to inflammasome activation, causing oxidative stress and inflammation. Since the latter 2 are implicated in the development of cardiovascular diseases, such as hypertension and atherosclerosis, it can be presumed that exposure to engineered nanomaterials could significantly impact cardiovascular function. In this review, I raise issues that should be considered in the assessment of the effects of engineered nanomaterials on cardiovascular function, and evaluate their cardiovascular toxicity as described in various in vitro and/or in vivo toxicological studies and industrial investigations.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11827124/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}