{"title":"Urinary benzyl alcohol and hippuric acid in workers exposed to benzyl alcohol during paint-stripping work.","authors":"Kenta Ishii, Akito Takeuchi, Masami Shimada, Hiromi Momokawa, Tomiko Tashiro, Ai Yamada, Kumiko Arai, Akira Namera, Kenji Yamamuro, Koichi Kato, Toshihiro Kawamoto, Ginji Endo","doi":"10.1093/joccuh/uiae059","DOIUrl":"10.1093/joccuh/uiae059","url":null,"abstract":"<p><strong>Objective: </strong>We aimed to develop a reliable gas chromatography-mass spectrometry (GC-MS) method for detecting urinary benzyl alcohol (BeOH) concentrations and assess the suitability of urinary BeOH as a biomarker for occupational BeOH exposure.</p><p><strong>Methods: </strong>Thirteen male participants exposed to BeOH during paint-stripping work provided preshift and postshift urine samples, and their personal exposure concentrations were measured. Meanwhile, a control group of 10 nonexposed workers contributed urine samples. The newly developed GC-MS method met regulatory guidelines.</p><p><strong>Results: </strong>The personal exposure concentrations of BeOH ranged from 8.4 to 45.2 mg/m3. Postshift urine samples from exposed participants showed significant BeOH and hippuric acid (HA) concentration increases compared with preshift samples (BeOH, post-/pre-shift geometric mean [GM] ratio = 7.5-7.8, P < .001; HA, post-/pre-shift GM ratio = 4.3-4.5, P < .001). These levels were considerably higher than those in postshift samples from the nonexposed control group (BeOH, exposed-/nonexposed-workers GM ratio = 14.8-19.0, P < .001; HA, exposed-/nonexposed-workers GM ratio = 12.1-15.3, P < .001), even after urine density correction.</p><p><strong>Conclusions: </strong>Urinary BeOH and HA can serve as potential biomarkers of occupational exposure to BeOH. More specifically, BeOH might serve as a biomarker superior to HA because it is apparently less influenced by confounding factors such as dietary intake and genetic polymorphism of low-Km aldehyde dehydrogenase (ALDH2). The findings will improve workplace safety measures and protocols, assisting health care professionals in diagnosing and managing exposure-related health issues, thereby potentially reducing the risk of occupational exposure to BeOH.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11561903/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142372079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of BMI changes in Japanese adults receiving face-to-face versus online counseling for specific health guidance: a noninferiority prospective observational study.","authors":"Satoru Kanamori, Kiyomi Tomiyama, Yasuo Haruyama","doi":"10.1093/joccuh/uiae026","DOIUrl":"10.1093/joccuh/uiae026","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to evaluate the noninferiority of online counseling over face-to-face counseling for specific health guidance (SHG).</p><p><strong>Methods: </strong>This prospective observational study was conducted using specific health checkup (SHC) and SHG data of individuals with health insurance in Japan. We analyzed data from 1431 participants who met the inclusion criteria, including those who underwent online or face-to-face counseling between April 1, 2020 and March 31, 2021, and received an SHC in the following year but no earlier than 90 days after their first counseling session. Assessed variables comprised demographics, counseling methods, and SHC results, including baseline questionnaire findings and body mass index (BMI) at follow-up. We performed inverse probability of treatment weighting (IPTW) using propensity scores, with changes in BMI as the objective variable and the counseling method as the explanatory variable. We set the noninferiority margin to 0.175, based on a previous study.</p><p><strong>Results: </strong>The online and face-to-face counseling groups comprised 455 (31.8%) and 976 (68.2%) participants, respectively. The number of men and mean age were 214 (47.0%) and 49.9 years (SD: 6.9 years), respectively, in the online counseling group, and 491 (50.3%) and 51.1 years (SD: 7.6 years), respectively, in the face-to-face counseling group. IPTW using propensity scores revealed a regression coefficient of -0.014 (95% CI: -0.157 to 0.129) for the online group compared with the face-to-face group (P = .847). The CI was within the noninferiority margin.</p><p><strong>Conclusions: </strong>The effects of online counseling on BMI are likely noninferior to those of face-to-face counseling.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11170213/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140903599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kosuke Sakai, Tomohisa Nagata, Takahiro Mori, Naozumi Sueyoshi, Shunsuke Inoue, Kiminori Odagami, Yoshiyuki Shibata, Koji Mori
{"title":"The individual and work-related factors associated with the occupational future time perspective: a cross-sectional study of older workers in Japan.","authors":"Kosuke Sakai, Tomohisa Nagata, Takahiro Mori, Naozumi Sueyoshi, Shunsuke Inoue, Kiminori Odagami, Yoshiyuki Shibata, Koji Mori","doi":"10.1093/joccuh/uiae032","DOIUrl":"10.1093/joccuh/uiae032","url":null,"abstract":"<p><strong>Objectives: </strong>Occupational future time perspective (OFTP) is important concept for a successful career in older workers. The purpose of this study was to examine the associations between individual and work-related factors and OFTP.</p><p><strong>Methods: </strong>We conducted a cross-sectional study via an online questionnaire survey. Respondents were stratified sampled according to the distribution of workers across Japan. To assess OFTP, we used the Japanese version of the OFTP scale. We included factors such as sex, age, education, marital status, subjective health status, personal income, length of employment, industry, size of company, employment status, working days per week, and night shift. Multiple regression analysis was employed to calculate the regression coefficients for each factor, with OFTP serving as the dependent variable.</p><p><strong>Results: </strong>In total we included 1484 respondents. Our findings indicated that higher OFTP was associated with higher education, better subjective health status, higher personal income, and smaller size of company. Compared with manufacturing, certain industries such as agriculture and forestry, transportation and postal services, and health care showed lower OFTP. In contrast to permanent workers, contract and part-time workers demonstrated lower OFTP, whereas owners of non-family businesses exhibited higher OFTP. Furthermore, individuals working 1-4 d/wk showed lower OFTP compared with those working 5 d/wk.</p><p><strong>Conclusions: </strong>Older workers facing limitations in resources, such as educational background, personal income, precarious employment, and health status, tend to have lower OFTP. Such individuals should be given priority for support and assistance.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11360179/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141498308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A longitudinal study of rotating shift type and attention performance of acute and critical care nurses with chronotype as moderator variable.","authors":"Ai Lee, Yen-Kuang Lin, Yu-Huei Lin, Wen-Pei Chang","doi":"10.1093/joccuh/uiae042","DOIUrl":"10.1093/joccuh/uiae042","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate whether chronotype is a moderator variable that also interacts with shift type and whether they jointly influence the attention performance of nurses working in acute and critical care units.</p><p><strong>Methods: </strong>We adopted a longitudinal research design focusing on nurses working rotating shifts in the emergency room and intensive care units at a medical center. A total of 40 complete samples were obtained. Data analysis was conducted using the generalized estimating equations in SAS 9.4.</p><p><strong>Results: </strong>The mean (SD) age of the participants was 26.35 (2.12) years. After controlling for age, gender, and sleep duration, an interaction effect was discovered between a specific chronotype and shift type; that is, the interaction effect between chronotype and shift type was only significant when comparing late-types working the night shift with early- and intermediate-types working the night shift (B = -18.81, P = .011). The least squares means of the mean reaction time of the interaction effects between the 2 chronotype groups and the 3 shift types found that the mean reaction time of late-types working the night shift was 11.31 ms (P = .044) slower compared with working the day shift.</p><p><strong>Conclusions: </strong>The chronotype is a moderator variable between shift type and mean reaction time, such that matching the chronotype of nurses in acute and critical care units with the appropriate shift type improved their mean reaction time. It is hoped that the results of this study could serve as a reference for acute and critical care nurses when scheduling their shifts.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11360591/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141748368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"Occupational health staff's involvement contributes to supervisor's perceived organizational support in Japanese workforce: a prospective cohort study\".","authors":"I Wayan Gede Suarjana","doi":"10.1093/joccuh/uiae066","DOIUrl":"10.1093/joccuh/uiae066","url":null,"abstract":"","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11635819/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142546047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Raphael Kanyire Seidu, Emmanuel Abankwah Ofori, Benjamin Eghan, George Kwame Fobiri, Alex Osei Afriyie, Richard Acquaye
{"title":"A systematic review of work-related health problems of factory workers in the textile and fashion industry.","authors":"Raphael Kanyire Seidu, Emmanuel Abankwah Ofori, Benjamin Eghan, George Kwame Fobiri, Alex Osei Afriyie, Richard Acquaye","doi":"10.1093/joccuh/uiae007","DOIUrl":"10.1093/joccuh/uiae007","url":null,"abstract":"<p><strong>Objectives: </strong>The purpose of this study was to present a systematic review of the health-related problems of factory workers in the textile and fashion industry. These workers endure long sitting postures, poor workspace conditions, and long working hours to complete their overload of tasks. This situation results in several health problems that affect the productivity, mental health, and well-being of the workers.</p><p><strong>Methods: </strong>The relevant data (21 article publications) were obtained from the Scopus database. Analysis of the 21 articles was grouped under 3 research themes based on the critical reading of the content and abstracts: respiratory problems, musculoskeletal disorders, and psychological stressors and other health issues.</p><p><strong>Results: </strong>The findings show that factory workers are exposed to dust particles of cotton and other raw materials, fumes, and chemicals from manufacturing processes. This prolonged exposure without the use of personal protective equipment (PPE) leads to respiratory diseases like byssinosis that affect the workers' health. Additionally, working in a particular posture due to the workstation design for prolonged hours causes musculoskeletal disorders or pains. Workers also suffer from anxiety, depression, and stress from workload and pressure, hence making them unstable with reduced productivity.</p><p><strong>Conclusions: </strong>The findings of the study reinforce the need for a safe workspace and spacious work environment, provision of PPE, training in occupational hazards, frequent health checks, and ergonomic assessment of workstations to reduce prolonged work postures. Stakeholders, employers, policymakers, and governments should collaborate to safeguard and protect the well-being and health of the workers at these factories.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10964409/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139642340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Global, regional, and national burden of cancers attributable to occupational risks from 1990 to 2019.","authors":"Shiliang Ling, Lihong Zhou, Yanfeng Wu, Xiaoling Zhang, Wulong Han, Lihua Cui, Zhiyu Luan","doi":"10.1093/joccuh/uiae040","DOIUrl":"10.1093/joccuh/uiae040","url":null,"abstract":"<p><strong>Background: </strong>Based on data from the Global Burden of Disease study, the burden of cancer attributable to occupational risks between 1990 and 2019 was explored.</p><p><strong>Methods: </strong>The estimated burden in different regions was compared in terms of the age-standardized death rates (ASDRs), age-standardized disability-adjusted life years (DALYs) rates, and corresponding estimated annual percentage changes (EAPCs). The comparative risk assessment framework was used to estimate the risk of death and DALYs attributable to occupational risk factors.</p><p><strong>Results: </strong>Globally from 1990 to 2019, ASDRs decreased (EAPC = -0.69; 95% CI: -0.76 to -0.61), and age-standardized DALY rates decreased (EAPC = -0.99; 95% CI: -1.05 to -0.94). In terms of the global age distribution of cancer attributable to occupational risk factors, the death rate and DALY rates increased with age. In addition, from 1990 to 2019, the number of deaths, DALYs, ASDRs, and age-standardized DALY rates in men were higher than those in women, and the cancer burden grew fastest in Georgia (EAPC = 5.04), Croatia (EAPC = 4.01), and Honduras (EAPC = 3.54). Moreover, as the sociodemographic index (SDI) value of a country or region increased, its burden of cancer attributable to occupational risk factors rapidly increased.</p><p><strong>Conclusions: </strong>The global cancer burden attributable to occupational risk factors declined from 1990 to 2019, was higher in men than in women, and was concentrated in middle-aged and older adults. The baseline cancer burdens of regions or countries increased as their SDI values increased and were especially high in high-SDI regions or countries.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11378634/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141752011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of changes in commuting mode on body weight among Japanese workers: a longitudinal study.","authors":"Atsuko Fukunishi, Masaki Machida, Hiroyuki Kikuchi, Yutaka Nakanishi, Shigeru Inoue","doi":"10.1093/joccuh/uiae027","DOIUrl":"10.1093/joccuh/uiae027","url":null,"abstract":"<p><strong>Objective: </strong>The health benefits of active commuting have been reported. However, few studies have assessed commuting modes using objective methods. This study clarified the association between changes in objectively measured commuting modes and body weight among Japanese workers.</p><p><strong>Methods: </strong>This longitudinal study used data from the annual health examinations and personnel records of a company with branches in all prefectures of Japan. Data from 2018 and 2019 were used as the baseline and follow-up data, respectively. The commuting mode was assessed using the commuting mode code included in the personnel records and classified into 3 types: walking, public transport, and car or motorcycle. The participants were classified into 9 categories based on the combination of their commuting modes in 2018 and 2019. Body weight was measured objectively during health examinations. The 1-year changes in body weight were calculated for the 9 categories and assessed using an analysis of covariance with adjustments for covariates.</p><p><strong>Results: </strong>The analysis included 6551 workers (men: 86.8%; mean age: 42.8 years). Overall, body weights tended to increase (+0.40 kg/y). The participants who switched to more active commuting, such as from car or motorcycle to walking (-0.13 kg/y), from car or motorcycle to public transport (+0.10 kg/y), and from public transport to walking (-0.07 kg/y), exhibited small weight gains or losses. A similar trend was observed even after adjustment.</p><p><strong>Conclusions: </strong>Changing to a more active commuting mode may prevent weight gain among workers.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11285781/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141087913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Japanese fathers' work-related factors associated with involvement in childcare.","authors":"Manami Ochi, Tsuguhiko Kato, Yuko Kachi, Bibha Dhungel, Mako Nagayoshi, Yuichi Ichinose, Kenji Takehara","doi":"10.1093/joccuh/uiae036","DOIUrl":"10.1093/joccuh/uiae036","url":null,"abstract":"<p><strong>Objectives: </strong>Existing studies of fathers' involvement in childcare have focused on its impact on children's psychosocial development and the facilitation of family functions, like marital relationships. In this study, we investigated the factors that determine paternal childcare in Japan, particularly focusing on work-related hours and environment, separately, according to mothers' employment status.</p><p><strong>Methods: </strong>We used data from the Longitudinal Survey of Newborns in the 21st Century (2010 cohort) conducted in Japan. We restricted the sample to 27 783 participants with working fathers and analyzed how paternal work-related factors affect fathers' childcare involvement by mothers' employment status using an ordered logistic regression model.</p><p><strong>Results: </strong>In the model adjusting for all covariates, the odds ratio (OR) of spending less time with children on weekdays was higher: for fathers who worked 50 and more hours per week compared with those who worked 40-49 hours per week (OR = 1.95, 95% CI: 1.72-2.20 for 50-59 hours), for fathers whose commuting hours were longer than those commuting less than 0.5 hours per day (OR = 2.93, 95% CI: 2.34-3.69 for 1.5 or more hours), for larger workplace employee sizes than for 5-99 employee sizes (OR = 1.56, 95% CI: 1.38-1.77 for 500 or more employees). The associations between these paternal work-related variables and paternal hours spent with the children on weekdays were almost the same if the mothers were working or not working.</p><p><strong>Conclusions: </strong>Regardless of whether the mother is working, fathers' work environment factors, such as working hours, play a key role in their involvement in childcare.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11322603/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141616642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Satsue Nagahama, Bibha Dhungel, Ai Hori, Takehiro Michikawa, Keiko Asakura, Yuji Nishiwaki
{"title":"Changes in the frequency and amount of alcohol intake before and during the COVID-19 pandemic.","authors":"Satsue Nagahama, Bibha Dhungel, Ai Hori, Takehiro Michikawa, Keiko Asakura, Yuji Nishiwaki","doi":"10.1093/joccuh/uiae055","DOIUrl":"10.1093/joccuh/uiae055","url":null,"abstract":"<p><strong>Objectives: </strong>Concerns have been raised regarding the impact of the COVID-19 pandemic on alcohol consumption patterns, which can have implications for public health. In this descriptive study, we aimed to show the change in the frequency and amount of alcohol consumption in Japan before and during the COVID-19 pandemic periods.</p><p><strong>Methods: </strong>We analyzed data from annual health checkups among Japanese workers from April 2018 to March 2021. Changes in the frequency (daily, occasionally, rarely/never) and amount per one-time (4 categories by Japanese alcohol unit) of alcohol consumed among 331 200 participants were summarized by sex as 1-year changes in the periods before (fiscal year [FY] 2018 to FY 2019) and during (FY 2019 to FY 2020) the COVID-19 pandemic.</p><p><strong>Results: </strong>Among daily drinkers and rarely/never drinkers, overall, 1-year changes in the frequency of alcohol consumption during the pandemic were mostly consistent with changes before the pandemic, for both sexes. The number of occasional drinkers who drank less frequently a year later increased during the pandemic compared with before the pandemic (from 9.6% to 11.6% among men and from 12.9% to 16.5% among women); however, occasional drinkers who drank more frequently showed a small increase. Collectively, both men and women showed a slight decrease in both the frequency and amount of alcohol consumption during the pandemic among occasional drinkers.</p><p><strong>Conclusions: </strong>No major shifts in alcohol consumption habits occurred during the pandemic in our study population. Occasional drinkers tended to drink less during the pandemic, suggesting that initial concerns about increased alcohol consumption owing to the pandemic were unfounded.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11561262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142468134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}