Journal of oleo science最新文献

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Oleoresin Extraction from Zingiber officinale Using Hot Compressed Water Extraction. 热压缩水萃取法提取生姜油树脂。
IF 1.8 4区 农林科学
Journal of oleo science Pub Date : 2026-01-01 DOI: 10.5650/jos.ess25169
Syahrul Affandi Saidi, Mohd Al Hafiz Mohd Nawi, Nik Muhammad Azhar Nik Daud, Mohd Sharizan Md Sarip, Amirul Ridzuan Abu Bakar, Mohd Asraf Mohd Zainudin, Ahmad Hazim Abdul Aziz
{"title":"Oleoresin Extraction from Zingiber officinale Using Hot Compressed Water Extraction.","authors":"Syahrul Affandi Saidi, Mohd Al Hafiz Mohd Nawi, Nik Muhammad Azhar Nik Daud, Mohd Sharizan Md Sarip, Amirul Ridzuan Abu Bakar, Mohd Asraf Mohd Zainudin, Ahmad Hazim Abdul Aziz","doi":"10.5650/jos.ess25169","DOIUrl":"10.5650/jos.ess25169","url":null,"abstract":"<p><p>Ginger is traditionally processed into two main products: ginger oleoresin and oil using solvent extraction and hydro-distillation, respectively. However, these methods have limitations, including the use of organic solvents, long extraction times, and poor selectivity. In this study, hot compressed water extraction (HCWE) was evaluated as an alternative, and its performance was compared with conventional methods in terms of yield, physical characteristics, and concentration of key bioactive compounds. The HCWE was conducted at a constant pressure of 3.5 MPa and varying temperatures between 130°C and 200°C. The resulting extracts were analyzed using High-Performance Liquid Chromatography (HPLC) to quantify 6-gingerol, 6-shogaol, and 10-gingerol concentration. HCWE process at temperature of 140°C, pressure of 3.5 MPa and 30 minutes extraction time obtains higher extraction yield of 10.37 ± 0.33 % (g/g) in comparison with solvent extraction for 480 minutes at 7.57 ± 0.31 % (g/g). But it resulted in lower concentrations of 6-gingerol at 1957.22 ± 2.55 µg/g and undetectable levels of 6-shogaol. As temperature increased to 170°C, the concentration of 6-gingerol decrease to 851.95 ± 2.34 µg/g and 6-shogaol concentration increase to 1135.23 ± 1.18 µg/g demonstrating HCWE's temperature-driven selectivity. Above 170 °C, both compounds degraded significantly, and the extract quality declined. The HCWE extract resembled ginger oleoresin in texture and aroma, suggesting its suitability for similar applications. In contrast, solvent extraction produced a broader range of compounds but lacked selectivity. In conclusion, this study demonstrates that the HCWE process is a rapid, organic solvent-free extraction method which not only reduces processing time by more than 80 % compared with conventional solvent extraction, but also provides temperature-driven selectivity, underscoring its potential for greener, industrial-scale applications in functional food and phytochemical production. These findings highlight the promise of HCWE as a sustainable approach for phytochemical extraction and functional food development.</p>","PeriodicalId":16626,"journal":{"name":"Journal of oleo science","volume":"75 3","pages":"347-356"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147325978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lactone and Aldehyde Release Behavior of Canola Oil Modified using Sterols and Their Derivatives. 甾醇及其衍生物改性菜籽油的内酯和醛释放行为
IF 1.8 4区 农林科学
Journal of oleo science Pub Date : 2026-01-01 DOI: 10.5650/jos.ess25241
Natsuki Yurue, Aya Yoshinaga-Kiriake, Aina Yamazaki, Yuriko Suganuma, Shota Koishi, Kazuaki Yoshinaga
{"title":"Lactone and Aldehyde Release Behavior of Canola Oil Modified using Sterols and Their Derivatives.","authors":"Natsuki Yurue, Aya Yoshinaga-Kiriake, Aina Yamazaki, Yuriko Suganuma, Shota Koishi, Kazuaki Yoshinaga","doi":"10.5650/jos.ess25241","DOIUrl":"https://doi.org/10.5650/jos.ess25241","url":null,"abstract":"<p><p>This study examined the effects of sterols (β-sitosterol) and their derivatives, such as sterol fatty acid ester (β-sitosteryl palmitate) and sterol ferulic acid ester (γ-oryzanol), on the release of 25 added volatile compounds from canola oil using headspace solid-phase microextraction coupled with gas chromatography-mass spectrometry. δ- and γ-lactone release decreased after adding β-sitosterol or γ-oryzanol, in association with octanol-water partition coefficients (LogP). Moreover, only aldehydes with low LogP were suppressed. Hydroxyl groups in β-sitosterol or γ-oryzanol may play a key role in modulating volatile release. These findings provide insight into the aromatic retention mechanisms of oils.</p>","PeriodicalId":16626,"journal":{"name":"Journal of oleo science","volume":"75 4","pages":"379-387"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147592841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Researching on Optimization and Evaluation Some Biological Activities of Polyphenol Extract from Avocado Seeds (Persea americana Mill). 牛油果种子多酚提取物的生物活性优化及评价研究。
IF 1.8 4区 农林科学
Journal of oleo science Pub Date : 2026-01-01 DOI: 10.5650/jos.ess25233
Nguyen Thi Truc Loan, Nguyen Thi Hien, Thien Hien Tran, Thi Kim Ngan Tran
{"title":"Researching on Optimization and Evaluation Some Biological Activities of Polyphenol Extract from Avocado Seeds (Persea americana Mill).","authors":"Nguyen Thi Truc Loan, Nguyen Thi Hien, Thien Hien Tran, Thi Kim Ngan Tran","doi":"10.5650/jos.ess25233","DOIUrl":"https://doi.org/10.5650/jos.ess25233","url":null,"abstract":"<p><p>Optimization of polyphenol extraction from avocado seeds and systematic evaluation of the bioactivity of fractions in two different solvents. This research aimed to optimize the extract parameters of polyphenol from avocado seed and evaluate antimicrobial and antioxidant activities of crude polyphenol extract and its fraction in dichloromethane and ethyl acetate. The study utilized ultrasound-assisted extraction (UAE) and response surface methodology (RSM) to optimize extraction parameters that were ethanol 61.082 % concentration, an extraction temperature of 59.986 °C, and an extraction time of 3.09 hours. The crude polyphenol extract contained 42.208 mg GAE/g DW and antioxidant activity of extracts were expressed as percentage of DPPH radicals inhibition with an IC<sub>50</sub> value of 117 μg/mL. Following the liquid-liquid fractionation of the crude extract with dichloromethane and ethyl acetate obtained ethyl acetate fraction was found to content 74.65 mg GAE/g DW and showed the highest antioxidant activity, with an IC<sub>50</sub> value of 62.04 μg/mL. The antimicrobial tests against some pathogenic bacteria showed that both the crude and ethyl acetate extracts were effective against Escherichia coli and Salmonella spp. Notably, the crude extract inhibited Aspergillus flavus at 100 mg/mL, while the ethyl acetate fraction did not exhibit inhibitory activity at the concentrations tested.</p>","PeriodicalId":16626,"journal":{"name":"Journal of oleo science","volume":"75 5","pages":"537-550"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147839204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Edible Insect Locusta migratoria, an Alternative Food Resource, Ameliorates Orotic Acid-induced Hypertriglyceridemia in Rats. 可食用昆虫迁徙蝗,一种替代食物资源,改善食用酸诱导的大鼠高甘油三酯血症。
IF 1.8 4区 农林科学
Journal of oleo science Pub Date : 2026-01-01 DOI: 10.5650/jos.ess25283
Masaru Ochiai, Tsugumi Yoshida, Jun Nagasao
{"title":"Edible Insect Locusta migratoria, an Alternative Food Resource, Ameliorates Orotic Acid-induced Hypertriglyceridemia in Rats.","authors":"Masaru Ochiai, Tsugumi Yoshida, Jun Nagasao","doi":"10.5650/jos.ess25283","DOIUrl":"https://doi.org/10.5650/jos.ess25283","url":null,"abstract":"<p><p>The anticipated increase in the global population and dyslipidemia will need available food resources, such as edible insects, to meet nutritional and pharmaceutical merits. Among edible insects, Locusta migratoria (namely, migratory locust) (ML), which contains n-3 fatty acids capable of binding to multiple lipids, phytosterols, and dietary fiber chitin, are expected to be a therapeutic resource for ameliorating dyslipidemia as well as an alternative protein resource. We hypothesized that the ML supplementation represented the beneficial effect on lipid metabolism in the plasma and liver of male rats with dyslipidemia induced by an AIN-93G based diet containing a low level of orotic acid (OA) (0.6 % in diet) for two weeks. The 0.6 % OA treatment, which was determined in a preliminary study on loading dosage suitable for evaluating food ingredients, did not affect the growth and severe lipid accumulation, but induced liver hypertrophy with low-moderate hematological observations and hypertriglyceridemia. The ML supplementation led to a reduction in plasma triacylglycerol levels in OA-treated rats, particularly in the chylomicron, very-low-density lipoprotein, and low-density lipoprotein (LDL), particularly small-dense LDL, fractions. In the liver, the ML supplementation also significantly or slightly reduced mRNA expression related to lipogenesis and LDL uptake genes, including Srebf2, Ldlr, Psck9, Hmgcr, Acaca, and Scd1. Moreover, the ratios of n-3 fatty acids, such as α-linolenic and docosapentanoic acids, were increased in the liver and the indices representing fatty acid desaturation in the plasma were suppressed following the ML supplementation. These results have agreed with our hypothesis that the ML supplementation ameliorates lipid metabolism by modulating hepatic lipogenesis, fatty acid metabolism, and LDL receptor function in OA-treated rats. Therefore, ML can serve as a functional and alternative food resource for ameliorating hypertriglyceridemia.</p>","PeriodicalId":16626,"journal":{"name":"Journal of oleo science","volume":"75 5","pages":"607-625"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147839227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
JIS Reference Liquid Detergent Considering the Characteristics of Commercially Available Liquid Detergents. 考虑到市售液体洗涤剂的特性,JIS参考液体洗涤剂。
IF 1.8 4区 农林科学
Journal of oleo science Pub Date : 2026-01-01 DOI: 10.5650/jos.ess25110
Sumiko Goto, Masaru Oya, Satomi Kuwabara, Yoshitaka Miyamae, Isao Yamada, Masafumi Nomura, Ryo Hyodo
{"title":"JIS Reference Liquid Detergent Considering the Characteristics of Commercially Available Liquid Detergents.","authors":"Sumiko Goto, Masaru Oya, Satomi Kuwabara, Yoshitaka Miyamae, Isao Yamada, Masafumi Nomura, Ryo Hyodo","doi":"10.5650/jos.ess25110","DOIUrl":"https://doi.org/10.5650/jos.ess25110","url":null,"abstract":"<p><p>In recent years, Japan has been moving away from powder detergents to liquid detergents, but only powder types have been set as standard indicator detergents for JIS detergency tests. Therefore, optimizing the liquid reference detergent composition, the standard model for commercial liquid detergents in the JIS K 3362 revision for household synthetic detergents, was studied based on the detergency and mechanism of commercial liquid and powder detergents. A JIS standard liquid composition was proposed based on the AATCC liquid detergent composition (the 2003 AATCC standard reference liquid laundry detergent), and detergency evaluations were conducted using a Terg-O-Tometer using natural collar dirt-soiled cloth and various commercially available soiled cloths. As a result, in the cleaning experiment using collar dirt-soiled cloth, the new JIS liquid reference detergent showed the same detergency as the conventional JIS powder detergent and commercial liquid detergents. It also showed the same detergency as commercial liquid detergents for artificial sebum stains, indicating that it is suitable as an indicator detergent for commercial liquid detergents. However, it was confirmed that there are some points to note, such as the fact that liquid detergents have a weaker alkaline component and, therefore, have a lower detergency for artificial sebum stains than powder detergents and that the new JIS reference liquid detergent has a higher cleaning power for triacylglycerol stains than commercially available liquid and powder detergents due to their high surfactant concentration.</p>","PeriodicalId":16626,"journal":{"name":"Journal of oleo science","volume":"75 1","pages":"11-20"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145900632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Houttuynia cordata Thunb. Essential Oil Inhibits Diffuse Large B-cell lymphoma Growth. 鱼腥草。精油抑制弥漫性大b细胞淋巴瘤生长
IF 1.8 4区 农林科学
Journal of oleo science Pub Date : 2026-01-01 DOI: 10.5650/jos.ess25089
Youmei Peng, Shangkun Liu, Xiaoqian Fu, Wenhuan Li, Jiayi Chen, Yinfeng Xie, Yarong Wang, Jian Wang, Xiaozhe Rong, Wenhui Yang, Zhihong Zhao, Weihong Zhang, Zhuangli Zhang
{"title":"Houttuynia cordata Thunb. Essential Oil Inhibits Diffuse Large B-cell lymphoma Growth.","authors":"Youmei Peng, Shangkun Liu, Xiaoqian Fu, Wenhuan Li, Jiayi Chen, Yinfeng Xie, Yarong Wang, Jian Wang, Xiaozhe Rong, Wenhui Yang, Zhihong Zhao, Weihong Zhang, Zhuangli Zhang","doi":"10.5650/jos.ess25089","DOIUrl":"10.5650/jos.ess25089","url":null,"abstract":"<p><p>Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma (NHL) with high clinical heterogeneity and poor prognosis. Therapeutic drugs that can effectively improve the survival rate of DLBCL patients are lacking. Houttuynia cordata Thunb. is a well-known Asian medicinal and edible plant with anti-inflammatory and anti-tumor activities. This study investigated the potential therapeutic benefits of Houttuynia cordata Thunb. Essential Oil (HEO) on DLBCL. We found that HEO inhibited the proliferation of SUDHL-4 cells, induced apoptosis and cell cycle arrest at G0/G1 phase in a time and concentration-dependent manner. Moreover, intraperitoneal administration of HEO (70, 150, and 230 mg/kg) dose-dependently inhibited tumor growth of DLBCL in an athymic nude mouse xenograft model, while no significant changes in body weight were observed, indicating no obvious toxicity. Network pharmacology analysis indicated that HEO mainly regulated protein phosphorylation and PI3K/Akt signaling pathway. Phospho-specific protein microarray results also showed that HEO regulated the phosphorylation of PI3K/Akt signaling pathway. Further investigation confirmed that HEO significantly inhibited the protein expression of p-PI3K and p-Akt. In addition, HEO decreased the protein expression of B-cell lymphoma 2 (Bcl-2) and increased the protein expression of Bcl-2-associated X (Bax) and caspase-3. Compound-target docking results displayed that bornyl acetate (the main components of HEO), caryophyllene oxide and terpineol had strong binding interactions with the active sites of PI3K and Akt, indicating they contribute to the therapeutic effect. These results demonstrated that HEO exerts anti-tumor effects in DLBCL via suppressing PI3K/Akt signaling pathway, indicating HEO may be a potential inhibitor of PI3K/Akt signaling pathway for the treatment of DLBCL.</p>","PeriodicalId":16626,"journal":{"name":"Journal of oleo science","volume":"75 3","pages":"331-345"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147325762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Newly Developed g-C3N4/Bauxite Composite: Microwave-Assisted Synthesis and Morphological Characterization. 一种新型g-C3N4/铝土矿复合材料:微波辅助合成及形态表征。
IF 1.8 4区 农林科学
Journal of oleo science Pub Date : 2026-01-01 DOI: 10.5650/jos.ess25273
Anwar Said, Maulina Maulina, Keyman Keyman
{"title":"A Newly Developed g-C<sub>3</sub>N<sub>4</sub>/Bauxite Composite: Microwave-Assisted Synthesis and Morphological Characterization.","authors":"Anwar Said, Maulina Maulina, Keyman Keyman","doi":"10.5650/jos.ess25273","DOIUrl":"https://doi.org/10.5650/jos.ess25273","url":null,"abstract":"<p><p>This study reports the successful synthesis of graphitic carbon nitride/bauxite (g-C<sub>3</sub>N<sub>4</sub>/bauxite) composites via a rapid and efficient microwave irradiation method. The primary aim was to investigate the influence of microwave-assisted synthesis on the morphological and structural properties of the resulting composites. Comprehensive characterization using Scanning Electron Microscopy-Energy Dispersive X-ray Spectroscopy (SEM-EDS) revealed a highly porous and uniformly dispersed microstructure, with homogeneous distribution of C, N, Al, Si, and O elements. This indicates the formation of abundant active sites favorable for surface-mediated interactions. X-ray diffraction (XRD) analysis confirmed the coexistence of distinct crystalline phases: characteristic bauxite reflections at 2θ ≈ 26.6° and 21-22°, alongside the typical (100) and (002) graphitic planes of g-C<sub>3</sub>N<sub>4</sub> at 2θ ≈ 13° and 27°, respectively. Fourier-transform infrared (FTIR) spectroscopy further verified the preservation of the heptazine-based polymeric framework in the composite. The integration of bauxite not only improved the textural properties but also enhanced the interfacial contact between the two phases. The obtained g-C<sub>3</sub>N<sub>4</sub>/bauxite composite exhibited a high surface area, well-developed porosity, and synergistic structural features, demonstrating its potential as an effective material for heavy metal removal and related environmental remediation applications.</p>","PeriodicalId":16626,"journal":{"name":"Journal of oleo science","volume":"75 4","pages":"499-509"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147592729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Antioxidant Activity and Phenolic Content of Medicinal Plants Extracted by Ethanol, Methanol, and Water. 乙醇、甲醇和水提取药用植物抗氧化活性及酚类物质含量的评价
IF 1.8 4区 农林科学
Journal of oleo science Pub Date : 2026-01-01 DOI: 10.5650/jos.ess25164
Burcu Çakmak Sancar, Halil İbrahim Binici, Meryem Akhan
{"title":"Evaluation of Antioxidant Activity and Phenolic Content of Medicinal Plants Extracted by Ethanol, Methanol, and Water.","authors":"Burcu Çakmak Sancar, Halil İbrahim Binici, Meryem Akhan","doi":"10.5650/jos.ess25164","DOIUrl":"https://doi.org/10.5650/jos.ess25164","url":null,"abstract":"<p><p>The aim of this study was to compare both the efficiency of different extraction solvents and the phenolic content of various plant species. Analyses included pH, total phenolic content (TPC), total flavonoid content (TFC), antioxidant capacity (FRAP, CUPRAC), and DPPH IC₅₀. Methanol extract pH ranged from hibiscus (Hibiscus sabdariffa L.) at 3.71 to 8.29 green tea leaf (Camellia sinensis L.). Quince leaf (Cydonia oblonga) water extract had the highest TPC (949.25 mg GAE/100 g) and flavonoid content (5166.21 mg QE/100 g). Lemon balm (Melissa officinalis) showed the highest FRAP and CUPRAC values in both methanol and water extracts. Rosehip (Rosa canina L.) water extract had the strongest DPPH activity (IC₅₀: 8.61 µg/mL). These findings suggest that lemon balm (Melissa officinalis), quince leaf (Cydonia oblonga), and rosehip (Rosa canina) have strong potential as functional food ingredients, owing to their rich phenolic and flavonoid content and potent antioxidant activities, which could be beneficial in preventing oxidative stress-related health conditions.</p>","PeriodicalId":16626,"journal":{"name":"Journal of oleo science","volume":"75 2","pages":"159-168"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146100296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of Ulcerative Colitis with Myrrh Essential Oil Microemulsion. 没药精油微乳治疗溃疡性结肠炎。
IF 1.8 4区 农林科学
Journal of oleo science Pub Date : 2026-01-01 DOI: 10.5650/jos.ess25047
Mengmeng Wang, Tiantian Tang, Mei Liu, Zihao Niu, Le Zhang, Xuan Wang, Ning Xia, Jie Wang, Jinhui Wang, Chao Chen, Xiaoxiao Ge, Qin Chen, Shihao Zhang, Huanxian Shi, Yundong Xie, Chongbo Zhao, Junbo Zou, Dongyan Guo, Yajun Shi, Ming Yang, Xiaofei Zhang, Jing Sun
{"title":"Treatment of Ulcerative Colitis with Myrrh Essential Oil Microemulsion.","authors":"Mengmeng Wang, Tiantian Tang, Mei Liu, Zihao Niu, Le Zhang, Xuan Wang, Ning Xia, Jie Wang, Jinhui Wang, Chao Chen, Xiaoxiao Ge, Qin Chen, Shihao Zhang, Huanxian Shi, Yundong Xie, Chongbo Zhao, Junbo Zou, Dongyan Guo, Yajun Shi, Ming Yang, Xiaofei Zhang, Jing Sun","doi":"10.5650/jos.ess25047","DOIUrl":"https://doi.org/10.5650/jos.ess25047","url":null,"abstract":"<p><p>Ulcerative colitis (UC) is a chronic inflammatory colon disease that is a major public health problem. The long-term administration of traditional drugs is likely to trigger adverse reactions. The myrrh essential oil (MEO) exhibits promising therapeutic efficacy against ulcerative colitis. However, due to the inherent instability and volatility of MEO, it was formulated into myrrh essential oil microemulsion (MM) with the aim of enhancing its stability. This study explored the optimal formulation for synthesizing MM, and a series of relevant indices were employed to meticulously investigate its stability characteristics. In animal experiments, a UC mouse model was established with the assistance of Dextran Sulfate Sodium (DSS). The therapeutic efficacy was comprehensively evaluated by recording Disease Activity Index (DAI) scores, detecting the levels of Tumor Necrosis Factor-α (TNF-α) and Interleukin-1β (IL-1β), and observing the morphological features of mouse colonic tissues through hematoxylin-eosin (HE) staining and immunohistochemistry (IHC) techniques. The results confirmed that both MEO and MM are effective in treating ulcerative colitis.</p>","PeriodicalId":16626,"journal":{"name":"Journal of oleo science","volume":"75 1","pages":"51-66"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145900695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunomodulatory and Anti-Inflammatory Potential of Shark Liver Oil: A Scoping Review of Human and Animal Studies. 鲨鱼鱼肝油的免疫调节和抗炎潜力:人类和动物研究的范围综述。
IF 1.8 4区 农林科学
Journal of oleo science Pub Date : 2026-01-01 DOI: 10.5650/jos.ess25208
Dalila Najia Suhaimi, Mohd Hanif Zulfakar
{"title":"Immunomodulatory and Anti-Inflammatory Potential of Shark Liver Oil: A Scoping Review of Human and Animal Studies.","authors":"Dalila Najia Suhaimi, Mohd Hanif Zulfakar","doi":"10.5650/jos.ess25208","DOIUrl":"https://doi.org/10.5650/jos.ess25208","url":null,"abstract":"<p><p>Shark liver oil (SLO) is commercially promoted as an immunity booster to fight off infections, heal wounds, and for its beneficial effects in cancer treatment. Despite the growing body of research on SLO, scattered data and reported outcomes in understanding its immunomodulatory and anti-inflammatory mechanisms exist across study designs and populations, and the experimental design variances complicate data interpretation for meaningful translation into clinical applications. This scoping review aims to address this by comprehensively charting human and animal models to identify patterns of immunomodulatory and anti-inflammatory effects of SLO and its bioactive components, thus highlighting areas requiring further investigation. A scoping search through Cochrane, PubMed<sup>®</sup>, MEDLINE<sup>®</sup> via Ovid and Scopus using keywords such as \"shark liver oil\", \"immunomodulation\", \"anti-inflammatory\", similar keywords and their combinations was performed. Quantitative and qualitative measurements of immune or inflammatory responses were recorded and mapped. A total of 16 articles met the inclusion criteria, including human studies and in vivo animal models with various baseline health conditions. SLO has a broad yet selective immunomodulatory effect that shows an adaptive response depending on context, such as inflammatory conditions, cancer, or infection. The inconsistencies in results highlighted the biological complexity and the context-dependent role of SLO in the immune system. Despite this, alkylglycerols (AKG) emerge as a key bioactive component, with some studies suggesting potential dose-dependent effects and exploring the structure-activity relationship of different AKG forms in modulating the immune response. Overall, the current evidence is promising but preliminary, with methodological differences in the literature that highlight a clear need for rigorous, standardized clinical trials.</p>","PeriodicalId":16626,"journal":{"name":"Journal of oleo science","volume":"75 2","pages":"87-103"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146100326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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