Journal of nutritional science and vitaminology最新文献_第9页

Suppressive Effect of Apple Juice Intake on Urinary Excretion of Ascorbic Acid: Unblinded Randomized Crossover Study in Healthy Japanese Subjects. 苹果汁对抗坏血酸尿排泄的抑制作用：日本健康受试者的非盲法随机交叉研究。

IF 0.7 4区医学

Journal of nutritional science and vitaminology Pub Date : 2024-01-01 DOI: 10.3177/jnsv.70.359

Hiromi Izawa, Suzuka Kato, Haruka Tatehana

引用次数: 0

Consumption of 1-Kestose Upregulates MicroRNA-200 and -192/215 Families in Lamina Propria Leukocytes of the Murine Large Intestine. 摄入1-Kestose可上调小鼠大肠固有层白细胞中的MicroRNA-200和-192/215家族。

IF 1.6 4区医学

Journal of nutritional science and vitaminology Pub Date : 2023-01-01 DOI: 10.3177/jnsv.69.150

Fumina Ohsaka, Daiki Honma, Yoshihiro Kadota, Takumi Tochio, Kei Sonoyama

{"title":"Consumption of 1-Kestose Upregulates MicroRNA-200 and -192/215 Families in Lamina Propria Leukocytes of the Murine Large Intestine.","authors":"Fumina Ohsaka, Daiki Honma, Yoshihiro Kadota, Takumi Tochio, Kei Sonoyama","doi":"10.3177/jnsv.69.150","DOIUrl":"https://doi.org/10.3177/jnsv.69.150","url":null,"abstract":"By comparing germ-free mice and specific pathogen-free mice, we recently demonstrated that the presence of gut commensals upregulates microRNA-200 family members in lamina propria leukocytes (LPL) of the murine large intestine. The present study tested whether the consumption of 1-kestose (KES), an indigestible oligosaccharide that alters gut microbiota composition, influences the microRNA expression in the LPL. Supplementation of KES (4%) in drinking water for 2 wk increased the levels of miR-182-5p, -205-5p, -290a-5p, miR-200 family members (miR-141-3p, -200a-3p, -200b-3p, -200c-3p, and -429-3p) as well as miR-192/215 family members (miR-192-5p, -194-5p, and -215-5p) as determined by microarray analysis in large intestinal LPL of C57BL/6 mice. Quantitative reverse transcription-PCR further confirmed the increase in miR-192-5p, -194-5p, -200a-3p, -200b-3p, -200c-3p, -205-5p, and 215-5p. KES consumption significantly increased Bifidobacterium pseudolongum in the cecal contents. In a separate experiment, intragastric administration of B. pseudolongum (109 CFU/d) for 7 d increased the levels of miR-182-5p, -194-5p, and -200a-3p and tended to increase the levels of miR-200b-3p, -215-5p, and -429-3p. These results suggest that dietary KES influences miRNA expression in the large intestinal LPL, which may be associated with the increased population of B. pseudolongum.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"69 2","pages":"150-154"},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9392560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Weak Inhibitory Effects of Anthocyanins on Human Aldehyde Oxidase Activity: An In Vitro Study. 花青素对人醛氧化酶活性弱抑制作用的体外研究

IF 1.6 4区医学

Journal of nutritional science and vitaminology Pub Date : 2023-01-01 DOI: 10.3177/jnsv.69.71

Yuma Shibata, Kaori Matsumoto, Tetsuya Hasegawa, Kosuke Ohara, Masayuki Akimoto

{"title":"Weak Inhibitory Effects of Anthocyanins on Human Aldehyde Oxidase Activity: An In Vitro Study.","authors":"Yuma Shibata, Kaori Matsumoto, Tetsuya Hasegawa, Kosuke Ohara, Masayuki Akimoto","doi":"10.3177/jnsv.69.71","DOIUrl":"https://doi.org/10.3177/jnsv.69.71","url":null,"abstract":"Aldehyde oxidase (AO) plays an important role in the metabolism of antitumor and antiviral drugs, including methotrexate, favipiravir, and acyclovir. The consumption of blueberry fruits or their extracts, which contain large amounts of anthocyanins, has recently increased. The intake of large amounts of anthocyanins occurs through the frequent consumption of blueberries or their functional foods, which may result in unwanted interactions between anthocyanins and medicinal drugs. Therefore, the present study examined the inhibition of AO by anthocyanins, anthocyanidins, and blueberry extracts in human liver cytosol using a HPLC assay. A comparison of the 50% inhibitory concentration (IC50) values of the test compounds showed that anthocyanidins slightly suppressed AO activity, whereas the inhibitory effects of anthocyanins and blueberry extracts were negligible. The inhibitory activities of the anthocyanins tested were approximately 60- to 130-fold weaker than that of the positive control menadione and were almost negligible. Furthermore, they were approximately 2,000-fold less potent than that of raloxifene, a typical AO inhibitor, and, thus, unlikely to interfere with drug metabolism by AO. In addition, since the plasma concentrations of anthocyanins after their administration were generally lower than the IC50 level, the inhibition of AO substrate metabolism by anthocyanins does not appear to be severe.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"69 1","pages":"71-75"},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10823780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Resistant Maltodextrin Suppresses Intestinal Phenols Production by Modifying the Intestinal Environment. 耐药麦芽糊精通过改变肠道环境抑制肠道酚类物质的产生。

IF 1.6 4区医学

Journal of nutritional science and vitaminology Pub Date : 2023-01-01 DOI: 10.3177/jnsv.69.268

Akane Kanasaki, Tomonori Kimura, Machiko Kitagawa, Yuka Kishimoto

{"title":"Resistant Maltodextrin Suppresses Intestinal Phenols Production by Modifying the Intestinal Environment.","authors":"Akane Kanasaki, Tomonori Kimura, Machiko Kitagawa, Yuka Kishimoto","doi":"10.3177/jnsv.69.268","DOIUrl":"https://doi.org/10.3177/jnsv.69.268","url":null,"abstract":"Protein is an essential nutrient that plays several roles in the maintenance of the human body. A high-protein diet is also known to play an important role in weight management in obese individuals and in maintaining muscle strength in the elderly. However, over-consumption of protein can have negative effects on health, including deterioration of the intestinal environment by the production of amino acid metabolites such as phenols. Interest in the regulation of the intestinal environment to maintain health has gained attention recently. Resistant maltodextrin (RMD) is a prebiotic dietary fiber. Therefore, we investigated whether RMD suppressed the production of amino acid metabolites through intestinal regulation in rats. Wistar rats were fed either an AIN-93G diet or a modified AIN-93G diet containing 5% tyrosine. RMD (2.5% or 5.0%) was provided with drinking water. The rats were fed these diets and water ad libitum for 3 wk. Urine was collected overnight, after which serum, liver, kidneys, and the whole cecum were collected from rats under anesthesia with isoflurane for analysis of phenols and microbiota. RMD decreased the cecal, serum, and urinary levels of phenols, especially phenol. Moreover, the relative abundance of intestinal Romboutsia ilealis showed a significant correlation with the cecal phenols levels, and RMD decreased the abundance of this species. Thus, RMD may suppress phenols production and decrease serum phenols levels by altering the intestinal environment in rats.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"69 4","pages":"268-274"},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10127440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Theophylline Prevents Dexamethasone-Induced Atrophy in C2C12 Myotubes. 茶碱对地塞米松诱导的C2C12肌管萎缩的预防作用。

IF 1.6 4区医学

Journal of nutritional science and vitaminology Pub Date : 2023-01-01 DOI: 10.3177/jnsv.69.284

Yasukiyo Yoshioka, Yukiko Imi, Kyuichi Kawabata, Katsumi Shibata, Junji Terao, Noriyuki Miyoshi

{"title":"Theophylline Prevents Dexamethasone-Induced Atrophy in C2C12 Myotubes.","authors":"Yasukiyo Yoshioka, Yukiko Imi, Kyuichi Kawabata, Katsumi Shibata, Junji Terao, Noriyuki Miyoshi","doi":"10.3177/jnsv.69.284","DOIUrl":"https://doi.org/10.3177/jnsv.69.284","url":null,"abstract":"Skeletal muscle mass is maintained by a balance between the synthesis and degradation of muscle proteins, the collapse of which causes muscle wasting. The prevention of muscle wasting improves the quality of life and extends a healthy life. The methyl xanthine theophylline showed strong preventive activity against dexamethasone-induced muscle atrophy, as determined using the expression level of myosin heavy chain in C2C12 myotubes. Mechanistically, theophylline inhibited the expression of ubiquitin ligases MuRF1 and Cbl-b, but not that of atrogin-1. Furthermore, theophylline inhibits glucocorticoid receptor translocation to the nucleus. A pull-down assay using a theophylline probe revealed that theophylline and dexamethasone competitively interacted with the glucocorticoid receptor, suggesting an antagonistic activity of theophylline on glucocorticoid receptors. Additionally, theophylline inhibited the dexamethasone-induced phosphorylation of p38 and FoxO3a in C2C12 myotubes. These findings suggest that theophylline is an effective food ingredient in the prevention of glucocorticoid-induced skeletal muscle atrophy.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"69 4","pages":"284-291"},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10127442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interaction between Prenatal and Postnatal Exposure to High-Fructose Corn Syrup Increases Gene Expression of Tnfa in Hippocampus of Offspring. 产前和产后高果糖玉米糖浆暴露增加后代海马Tnfa基因表达的相互作用

IF 1.6 4区医学

Journal of nutritional science and vitaminology Pub Date : 2023-01-01 DOI: 10.3177/jnsv.69.237

Mirai Yamazaki, Hiroya Yamada, Eiji Munetsuna, Yoshitaka Ando, Itsuki Kageyama, Nao Sadamoto, Yuki Nouchi, Atsushi Teshigawara, Genki Mizuno, Hiroaki Ishikawa, Koji Suzuki, Shuji Hashimoto, Koji Ohashi

{"title":"Interaction between Prenatal and Postnatal Exposure to High-Fructose Corn Syrup Increases Gene Expression of Tnfa in Hippocampus of Offspring.","authors":"Mirai Yamazaki, Hiroya Yamada, Eiji Munetsuna, Yoshitaka Ando, Itsuki Kageyama, Nao Sadamoto, Yuki Nouchi, Atsushi Teshigawara, Genki Mizuno, Hiroaki Ishikawa, Koji Suzuki, Shuji Hashimoto, Koji Ohashi","doi":"10.3177/jnsv.69.237","DOIUrl":"https://doi.org/10.3177/jnsv.69.237","url":null,"abstract":"Concerns about the negative intergenerational effects of excessive fructose intake are being raised, with evidence suggesting that prenatal fructose intake increases susceptibility to metabolic and cognitive dysfunction later in life. In the present study, we hypothesized that prenatal and postnatal fructose intake acts synergistically to impact on hippocampus of adult offspring. Female Sprague-Dawley rats received distilled water or 20% high-fructose corn syrup (HFCS) solution in addition to standard chow throughout gestation and lactation. Male offspring were weaned at postnatal day 21 (PD21) and were randomized to receive distilled water or 20% HFCS solution until PD60. The following experimental groups were: CC: distilled water dams and post-weaning distilled water, CH: distilled water dams and post-weaning HFCS solution, HC: HFCS solution dams and post-weaning distilled water and HH: HFCS solution dams and post-weaning HFCS solution. The synergistic effect of maternal and post-weaning HFCS intake on the hippocampus was investigated by studying the expression of pro-inflammatory cytokine genes (Tnfa, Il1b, and Il6). At weaning, expression levels of pro-inflammatory cytokines between the offspring of the distilled water and HFCS solution fed dams were not significantly different. At PD60, Tnfa expression was significantly higher in the HH group than in the CC, HC and CH groups, whereas no significant differences were found between the CC, HC, and CH groups. These results suggest that postnatal fructose intake negatively impacts the hippocampus by acting synergistically with prenatal fructose intake.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"69 4","pages":"237-242"},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10134154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application to Butterbur Products of a Suggested Daily Intake-Based Safety Evaluation of Individual Herbal Supplements with Cytochrome P450 Expression as a Major Index. 以细胞色素P450表达为主要指标的基于建议日摄入量的单个草药补充剂安全性评价在Butterbur产品中的应用。

IF 1.6 4区医学

Journal of nutritional science and vitaminology Pub Date : 2023-01-01 DOI: 10.3177/jnsv.69.206

Hiroko Hashida, Misaki Kurawaka, Haruka Tatehana, Anna Arita, Naho Sasaki, Fumio Shimura, Yuko Yamazaki

{"title":"Application to Butterbur Products of a Suggested Daily Intake-Based Safety Evaluation of Individual Herbal Supplements with Cytochrome P450 Expression as a Major Index.","authors":"Hiroko Hashida, Misaki Kurawaka, Haruka Tatehana, Anna Arita, Naho Sasaki, Fumio Shimura, Yuko Yamazaki","doi":"10.3177/jnsv.69.206","DOIUrl":"https://doi.org/10.3177/jnsv.69.206","url":null,"abstract":"The present paper first proposes a method for ensuring the safety of commercial herbal supplements, termed the suggested daily intake-based safety evaluation (SDI-based safety evaluation). This new method was inspired as a backward analog of the acceptable daily intake (ADI) derivation from the no observed adverse effect level (NOAEL), the basis of food additive risk analysis; namely, rats are dosed with individual herbal supplement products at the SDI for human use multiplied by 100 (the usual uncertainty factor value) per body weight for 8 d. The primary endpoint is the sign of adverse effects on liver, especially gene expression of cytochrome P450 (CYP) isoforms. The proposed method was then applied to three butterbur (Petasites hybridus) products without pyrrolizidine alkaloids but lacking clear safety information. Results showed that two oily products markedly enhanced the mRNA expression of CYP2B (>10-fold) and moderately enhanced that of CYP3A1 (<4-fold) with liver enlargement. These products also caused the renal accumulation of alpha 2-microglobulin. One powdery product showed no significant effect on liver and kidney. The large difference in effects of products was due to the difference in chemical composition revealed by liquid chromatography-mass spectroscopy. The oily and the powdery products required attention in terms of safety and effectiveness, respectively. Finally, the results from the SDI-based safety evaluation of butterbur and other herbal supplement products were grouped into four categories and cautionary notes were discussed. The SDI-based safety evaluation of their products by herbal supplement operators would contribute to safe and secure use by consumers.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"69 3","pages":"206-219"},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9742375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Herbal Leaves Can Suppress Oxidation of Perilla Oil. 草本植物叶子可以抑制紫苏油的氧化。

IF 1.6 4区医学

Journal of nutritional science and vitaminology Pub Date : 2023-01-01 DOI: 10.3177/jnsv.69.382

Shinji Yamashita, Azusa Miwa, Yu Hinata, Koji Urita, Kazuo Miyashita, Mikio Kinoshita

{"title":"Herbal Leaves Can Suppress Oxidation of Perilla Oil.","authors":"Shinji Yamashita, Azusa Miwa, Yu Hinata, Koji Urita, Kazuo Miyashita, Mikio Kinoshita","doi":"10.3177/jnsv.69.382","DOIUrl":"10.3177/jnsv.69.382","url":null,"abstract":"Perilla oil is a valuable food source of α-linolenic acids. However, its high reactivity with oxygen shortens its shelf-life after opening. This study investigated the antioxidative profiles of 15 plant materials, including herbs, and examined methods to suppress the oxidation of perilla oil using these plant materials. These plant materials had wide ranges of phenolic, carotenoid, and chlorophyll contents. They exhibit radical scavenging activities and suppress lipid peroxidation, which show highly positive correlations with the phenolic contents. Dipping most of the plant materials examined in perilla oil suppressed its oxidation, and the peroxide values of the oil mixtures indicated a negative correlation with the carotenoid and chlorophyll contents of the plant materials. The leaves of Angelica, Astragalus, and Thyme herbs exhibited the same effect as that of ascorbyl palmitate, which was used as a positive control after 8 wk of incubation in the dark. The suppression of lipid peroxidation was found to be related to the herbal contents of carotenoids and chlorophylls, rather than phenols. Hence, herbal leaves can suppress the oxidation of perilla oil in the dark. The oxidation of n-3 polyunsaturated fatty acids could be suppressed effectively by utilizing plant materials with abundant carotenoids and chlorophylls.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"69 5","pages":"382-387"},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71521771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effects of Overnight Fasting Duration on Glucose and Lipid Metabolism in a Sprague-Dawley Rat Model of Nonalcoholic Steatohepatitis with Advanced Fibrosis. 禁食时间对Sprague-Dawley大鼠非酒精性脂肪性肝炎伴晚期纤维化模型中葡萄糖和脂质代谢的影响。

IF 1.6 4区医学

Journal of nutritional science and vitaminology Pub Date : 2023-01-01 DOI: 10.3177/jnsv.69.357

Katsuhisa Omagari, Ayumi Maruta, Natsuki Yayama, Yuki Yoshida, Kyoko Okamoto, Bungo Shirouchi, Shouhei Takeuchi, Kazuhito Suruga, Kazunori Koba, Mayuko Ichimura-Shimizu, Koichi Tsuneyama

{"title":"The Effects of Overnight Fasting Duration on Glucose and Lipid Metabolism in a Sprague-Dawley Rat Model of Nonalcoholic Steatohepatitis with Advanced Fibrosis.","authors":"Katsuhisa Omagari, Ayumi Maruta, Natsuki Yayama, Yuki Yoshida, Kyoko Okamoto, Bungo Shirouchi, Shouhei Takeuchi, Kazuhito Suruga, Kazunori Koba, Mayuko Ichimura-Shimizu, Koichi Tsuneyama","doi":"10.3177/jnsv.69.357","DOIUrl":"10.3177/jnsv.69.357","url":null,"abstract":"Nonalcoholic steatohepatitis (NASH) can progress to hepatic fibrosis, and is associated with cardiovascular and liver-related mortality. To understand the pathogenesis of NASH, reliable animal models of the disease are useful. In animal studies, the animals are usually fasted overnight before biospecimens are taken, but little is known about the effects of fasting. Here, we investigated the impact of overnight fasting for approximately 9 to 17 h on glucose and lipid metabolism in a Sprague-Dawley (SD) rat model of diet-induced moderate and advanced NASH in comparison to normal SD rats. Our results revealed that in the moderate NASH model rats, the fasting duration did not affect glucose and lipid metabolism, the histopathological findings, or the hepatic mRNA expression levels of genes related to lipid metabolism, cholesterol metabolism, inflammation, fibrosis, and oxidative stress. In contrast, in the normal rats, significant fasting time-dependent reductions were observed in the epididymal fat pad weight and the hepatic mRNA expression levels of adipose differentiation-related protein and heme oxygenase-1. Moreover, in the advanced NASH model rats, a significant fasting time-dependent reduction and increase were observed in the serum insulin level and mRNA expression level of alpha-smooth muscle actin, respectively. Our present results suggest that the influence of the overnight fasting duration differs among the healthy condition, moderate NASH, and advanced NASH statuses. Further studies are needed in humans to determine the appropriate overnight fasting duration for the accurate evaluation of glucose and lipid metabolism in NASH patients.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"69 5","pages":"357-369"},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71521775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Index to the Authors of Volume 69. 第 69 卷作者索引。

IF 1.6 4区医学

Journal of nutritional science and vitaminology Pub Date : 2023-01-01 DOI: 10.3177/jnsv.69.499

引用次数: 0