Journal of nutritional science and vitaminology最新文献_第8页

Comparison of the Efficacy of Pre-Germinated Brown Rice Extract and γ-Oryzanol against Non-Alcoholic Fatty Liver Disease and Cardiac Complications Induced by a High-Fructose/Fat Diet. 预发芽糙米提取物和γ-谷米醇对高果糖/高脂肪饮食诱导的非酒精性脂肪性肝病和心脏并发症的疗效比较

IF 1.1 4区医学

Journal of nutritional science and vitaminology Pub Date : 2025-01-01 DOI: 10.3177/jnsv.71.321

Bin-Nan Wu, Hui-Li Lin, Huey-Jen Su, Pei-Wen Cheng, Ya-Mei Chen, Chi-Long Hao, Kuo-Ping Shen

{"title":"Comparison of the Efficacy of Pre-Germinated Brown Rice Extract and γ-Oryzanol against Non-Alcoholic Fatty Liver Disease and Cardiac Complications Induced by a High-Fructose/Fat Diet.","authors":"Bin-Nan Wu, Hui-Li Lin, Huey-Jen Su, Pei-Wen Cheng, Ya-Mei Chen, Chi-Long Hao, Kuo-Ping Shen","doi":"10.3177/jnsv.71.321","DOIUrl":"https://doi.org/10.3177/jnsv.71.321","url":null,"abstract":"This animal experiment aimed to evaluate the efficacy of the extract of pre-germinated brown rice (EP) and γ-oryzanol on non-alcoholic fatty liver disease (NAFLD) and the cardiac complications associated with it. WKY rats were fed high-fructose water (HFW) and high-fat diet (HFD) for 4 wk to induce NAFLD. The other two groups were fed HFW and HFD, while oral administration of EP 200 μL/kg or γ-oryzanol 2 mg/kg every day for 4 wk. NAFLD was successfully induced in as evidenced by clear increases in body, hepatic and cardiac weight as well as by increases in blood pressure and heart rate, hypertriglyceridemia, hyperuricemia, higher liver function index: glutamic pyruvic transaminase (GPT), higher levels of IL-6 and TNF-α in the blood and higher levels TG in the liver. NAFLD rats also had adverse changes the protein expressions of lipid synthesis, inflammation, cardiac fibrosis and hypertrophy. However, when the NAFLD rats were simultaneously fed EP or γ-oryzanol, the development of adverse diet-induced effects, including glutamic oxaloacetic transaminase (GOT), were clearly ameliorated. Specifically, EP could reduce uric acid levels, while γ-oryzanol did not. EP, as well as γ-oryzanol, reversed the increases in levels of lipid synthesis, inflammation, cardiac fibrosis and hypertrophy. We concluded that EP effectively prevented HFW/HFD-induced NAFLD and its associated cardiac complications, which it likely achieved through an improvement of lipid homeostasis and inhibition of inflammation. We believe that EP, like γ-oryzanol, can be developed as a beneficial agent for the prevention and control of NAFLD and associated cardiac dysfunction.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"71 4","pages":"321-330"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Oligonol^® Supplementation on Abdominal Fat in Japanese Overweight Volunteers: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study. 寡糖醇®补充剂对日本超重志愿者腹部脂肪的影响：一项随机、双盲、安慰剂对照、平行组研究。

IF 1.1 4区医学

Journal of nutritional science and vitaminology Pub Date : 2025-01-01 DOI: 10.3177/jnsv.71.357

Jun Takanari, Manami Misu, Kazunori Goto, Takuma Shio, Yukiko Fukuchi, Hajime Fujii, Jun Nishihira

{"title":"Effects of Oligonol® Supplementation on Abdominal Fat in Japanese Overweight Volunteers: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study.","authors":"Jun Takanari, Manami Misu, Kazunori Goto, Takuma Shio, Yukiko Fukuchi, Hajime Fujii, Jun Nishihira","doi":"10.3177/jnsv.71.357","DOIUrl":"https://doi.org/10.3177/jnsv.71.357","url":null,"abstract":"Obesity is known to induce diabetes, hypertension, and dyslipidemia, and reducing obesity is important from the perspective of disease prevention. Oligonol, a standardized oligomerized-polyphenol from Litchi chinensis fruit extract, is expected to have high absorption and body fat reduction. In this study, the effects of Oligonol intake on abdominal fat were examined in overweight Japanese participants. This randomized, double-blind, placebo-controlled trial was performed including 66 overweight adult men and women (body mass index [BMI] of 25 or more and less than 30 kg/m2) who were assigned to receive a daily dose of placebo or 200 mg Oligonol (40 mg as monomers and dimers of flavanols from lychee and tea) for 12 wk. The primary endpoint was a reduction of the visceral fat area (VFA) as quantified by computed tomography scanning after continual intake of test foods for 12 wk. In addition, body weight, BMI, waist circumference, peripheral blood tests, and general urinalysis were performed. Of 66 participants (33 per group), 63 were included in the efficacy analysis (placebo n=32; Oligonol n=31). Intake of 200 mg Oligonol significantly reduced abdominal VFA compared with the placebo group. No clinically relevant adverse events related to the intake of Oligonol were observed. These results indicate that Oligonol had the abdominal visceral fat reduction effect in overweight participants.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"71 4","pages":"357-365"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Inverse Association between Alcohol Consumption and Coronary Artery Disease in Japanese Men Undergoing Coronary Angiography. 在接受冠状动脉造影的日本男性中，饮酒与冠状动脉疾病的负相关

IF 0.7 4区医学

Journal of nutritional science and vitaminology Pub Date : 2025-01-01 DOI: 10.3177/jnsv.71.230

Emi Saita, Yoshimi Kishimoto, Reiko Ohmori, Kazuo Kondo, Yukihiko Momiyama

{"title":"The Inverse Association between Alcohol Consumption and Coronary Artery Disease in Japanese Men Undergoing Coronary Angiography.","authors":"Emi Saita, Yoshimi Kishimoto, Reiko Ohmori, Kazuo Kondo, Yukihiko Momiyama","doi":"10.3177/jnsv.71.230","DOIUrl":"https://doi.org/10.3177/jnsv.71.230","url":null,"abstract":"Several Japanese cohort studies reported that alcohol consumption was inversely associated with coronary artery disease (CAD). However, these results were inconsistent. We investigated alcohol consumption and CAD in 802 patients undergoing coronary angiography, in whom foods, beverages and alcohol intakes were assessed. Alcohol intake was classified into 4 categories: nondrinkers, light (<23 g/d), moderate (23-45 g/d), and heavy (≥46 g/d) drinkers. Among 583 men, CAD was found in 404, of whom 137 had myocardial infarction (MI). The prevalence of CAD and MI stepwisely decreased on alcohol intake: 80% and 30% in nondrinkers, 65% and 20% in light, 60% and 17% in moderate, and 54% and 16% in heavy drinkers (p<0.001). However, serum γ-GTP levels were higher in heavy drinkers than in nondrinkers. In multivariate analyses, odds ratios for <23 g/d, 23-45 g/d and ≥46 g/d alcohol intakes compared to nondrinkers was 0.53 (95%CI: 0.33-0.85), 0.44 (0.24-0.81), and 0.33 (0.16-0.68) for CAD, and 0.56 (0.34-0.90), 0.62 (0.32-1.20), and 0.43 (0.18-1.01) for MI. Among 219 women, CAD and MI were present in 107 and 36. Compared with nondrinkers, light and moderate to heavy drinkers less often had CAD (52%, 41%, and 29%) and MI (19%, 9%, and 14%), but these differences did not reach statistical significance. In women, no significant association was found between alcohol intake and CAD. Thus, in Japanese men undergoing coronary angiography, alcohol consumption was inversely associated with CAD, but heavy consumption was associated with abnormally high γ-GTP levels. In women, no significant association was found between alcohol consumption and CAD.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"71 3","pages":"230-237"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cephalotaxus harringtonia and Their Constituents Harringtonine Alkaloids Inhibit FoxO1 and 3a Activity and Atrophy-Related Gene Expression in C2C12 Myotubes. 尖嘴杉及其组成成分尖嘴杉碱生物碱抑制C2C12肌管FoxO1和3a活性及萎缩相关基因表达

IF 0.7 4区医学

Journal of nutritional science and vitaminology Pub Date : 2025-01-01 DOI: 10.3177/jnsv.71.256

Manami Kato, Tomoki Sato, Hiroyuki Fuchino, Hitomi Kawakami, Kayo Yoshimatsu, Kanako Iijima, Shino Hiraoka, Kun Tang, Yasuko Manabe, Nobuharu L Fujii, Yasutomi Kamei, Shinji Miura

{"title":"Cephalotaxus harringtonia and Their Constituents Harringtonine Alkaloids Inhibit FoxO1 and 3a Activity and Atrophy-Related Gene Expression in C2C12 Myotubes.","authors":"Manami Kato, Tomoki Sato, Hiroyuki Fuchino, Hitomi Kawakami, Kayo Yoshimatsu, Kanako Iijima, Shino Hiraoka, Kun Tang, Yasuko Manabe, Nobuharu L Fujii, Yasutomi Kamei, Shinji Miura","doi":"10.3177/jnsv.71.256","DOIUrl":"https://doi.org/10.3177/jnsv.71.256","url":null,"abstract":"The expression of the forkhead box O (FoxO) transcription factor, FoxO, in the skeletal muscle is involved in muscle atrophy caused by disuse, fasting, diabetes, and cachexia. Since inhibition of FoxO activity has been shown to be effective in preventing muscle atrophy in genetically engineered animals, inhibition of FoxO activity by dietary components may contribute to the prevention of muscle atrophy. In this study, 4,006 plant extracts were evaluated for FoxO1 and FoxO3a inhibitory activity using a reporter gene assay system, and the extracts from Cephalotaxus harringtonia showed potent inhibitory activities. These extracts also suppressed dexamethasone-induced expression of FoxO target genes, such as atrogin-1 and cathepsin L in C2C12 myotubes. Furthermore, harringtonine alkaloids, harringtonine and homoharringtonine, contained in Cephalotaxus harringtonia inhibited FoxOs activities and suppressed dexamethasone-induced expression of FoxO target genes in C2C12 myotubes, suggesting that harringtonine alkaloids contributed to the effects observed in C2C12 myotubes treated with Cephalotaxus harringtonia extract. However, these extracts and harringtonine alkaloids did not improve weakness in dexamethasone-atrophic myotubes. In conclusion, harringtonine alkaloids from Cephalotaxus harringtonia suppressed FoxO1 and 3a activity and the expression of their target atrophy genes in C2C12 myotubes, but these alkaloids had no the effect on dexamethasone-induced reduction in muscle contractility.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"71 3","pages":"256-266"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Probiotic Drinks Containing 2,3-Dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one on Cognitive Function of Middle-Aged and Older Individuals. 含2,3-二氢-3,5-二羟基-6-甲基- 4h -吡喃-4- 1益生菌饮料对中老年人认知功能的影响

IF 0.7 4区医学

Journal of nutritional science and vitaminology Pub Date : 2025-01-01 DOI: 10.3177/jnsv.71.223

Masato Tomizawa, Taiki Sato, Shuichi Segawa, Shin-Ichiro Iio, Tsuyoshi Takara

{"title":"Effect of Probiotic Drinks Containing 2,3-Dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one on Cognitive Function of Middle-Aged and Older Individuals.","authors":"Masato Tomizawa, Taiki Sato, Shuichi Segawa, Shin-Ichiro Iio, Tsuyoshi Takara","doi":"10.3177/jnsv.71.223","DOIUrl":"10.3177/jnsv.71.223","url":null,"abstract":"The compound 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one (DDMP) possesses antioxidant properties; however, its effects on cognitive function are unclear. This study examined the effects of DDMP-containing beverages on the cognitive function of healthy middle-aged and older Japanese individuals. We conducted a randomized, double-blind, and placebo-controlled parallel study. The study protocol was registered with the University Hospital Medical Network Clinical Trials Registry (UMIN000052639). In this study, 220 participants who were aware of their memory decline were enrolled and randomly assigned to the intervention or placebo group. The participants ingested the test food [65 mL lactic acid bacteria (LAB) beverage containing 2.2 mg DDMP] or placebo food (65 mL LAB beverage without DDMP) once a day for 12 wk. Cognitive function was assessed before the test and after 12 wk. The primary endpoint was verbal memory, while other cognitive function items and oxidative stress markers were set as the secondary outcomes. Differences in changes among the groups were assessed using analysis of covariance. After 12 wk, verbal and composite memory scores were considerably higher in the DDMP group than in the placebo group. However, no significant differences in oxidative stress markers were noticed. Therefore, consumption of a LAB beverage containing DDMP can markedly improve verbal and composite memory in middle-aged and older individuals with memory deterioration.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"71 3","pages":"223-229"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genistein and 17β-Estradiol Inhibit Extracellular Matrix Production and Chondroitin Sulfate Synthesis in ATDC5 Cells. 染料木素和17β-雌二醇抑制ATDC5细胞外基质生成和硫酸软骨素合成。

IF 1.1 4区医学

Journal of nutritional science and vitaminology Pub Date : 2025-01-01 DOI: 10.3177/jnsv.71.456

Seika Takeda, Kae Warita, Aki Fujiwara, Chisaki Asatsuma, Yuki Saito-Matsuzawa, Kota Shiozawa, Hideyuki Sone, Shin Kamiyama

{"title":"Genistein and 17β-Estradiol Inhibit Extracellular Matrix Production and Chondroitin Sulfate Synthesis in ATDC5 Cells.","authors":"Seika Takeda, Kae Warita, Aki Fujiwara, Chisaki Asatsuma, Yuki Saito-Matsuzawa, Kota Shiozawa, Hideyuki Sone, Shin Kamiyama","doi":"10.3177/jnsv.71.456","DOIUrl":"https://doi.org/10.3177/jnsv.71.456","url":null,"abstract":"Genistein is one of the most estrogenic soy isoflavones. This study investigated the effects of genistein and 17β-estradiol (E2) on early chondrogenesis and extracellular matrix (ECM) production in chondrogenic ATDC5 cells. At low concentrations, E2, but not genistein, enhanced chondrogenic differentiation. Higher concentrations of E2 and genistein suppressed ECM production and expression of genes involved in chondroitin sulfate (CS) proteoglycan synthesis, including aggrecan core protein, CS synthases, 3'-phosphoadenosine 5'-phosphosulfate (PAPS) synthases, PAPS transporters, and CS sulfotransferases. Genistein exerted a stronger inhibitory effect than E2 and completely abolished the increase in Tgfb1 gene expression during chondrogenic differentiation. Treatment with estrogen receptor antagonist ICI 182780 did not inhibit E2- or genistein-dependent inhibition of chondrogenesis. Furthermore, E2 and genistein exhibited equivalent partial inhibition of transforming growth factor beta (TGF-β)-induced upregulation of Acan and Col2a1 expression. These results indicate that the inhibitory effects of high concentrations of E2 and genistein are dependent on TGF-β, but not the estrogen receptor pathway.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"71 5","pages":"456-466"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145438325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Errata. 勘误表。

IF 1.1 4区医学

Journal of nutritional science and vitaminology Pub Date : 2025-01-01 DOI: 10.3177/jnsv.71.394

引用次数: 0

Active Vitamin D Corrects Cerebrovascular Dysfunction and Aberrant Vasopressin Expression in the Hypertension Phenotype of 1α-Hydroxylase Knockout Mice. 活性维生素D纠正1α-羟化酶敲除小鼠高血压表型中的脑血管功能障碍和血管加压素表达异常

IF 1.1 4区医学

Journal of nutritional science and vitaminology Pub Date : 2025-01-01 DOI: 10.3177/jnsv.71.290

Wei Zhang, Yingying Hu, Luqing Zhang, Ping Dong, Dongmei Li, Ronghui DU

{"title":"Active Vitamin D Corrects Cerebrovascular Dysfunction and Aberrant Vasopressin Expression in the Hypertension Phenotype of 1α-Hydroxylase Knockout Mice.","authors":"Wei Zhang, Yingying Hu, Luqing Zhang, Ping Dong, Dongmei Li, Ronghui DU","doi":"10.3177/jnsv.71.290","DOIUrl":"https://doi.org/10.3177/jnsv.71.290","url":null,"abstract":"Vitamin D has a protective effect on the brain under hypertensive conditions. Studies have shown that 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) can negatively regulate hypertension and central renin-angiotensin system activation through a central anti-oxidative mechanism in 1α-hydroxylase knockout mice. To confirm whether endogenous or exogenous 1,25(OH)2D3 deficiency or supplementation alters cerebrovascular function and vasopressin expression through anti-oxidation, researchers provided 1α(OH)ase-/- mice and their wild-type littermates with regular diet, a high-calcium, high-phosphorus rescue diet with N-acetyl-L-cysteine supplementation, or 1,25(OH)2D3 subcutaneous injection. The results showed that the hypertension phenotype was present in the 1α(OH)ase-/- mice, with upregulated vasopressin expression and increased brain/blood oxidative stress. These pathologic changes were corrected by 1,25(OH)2D3 or N-acetyl-L-cysteine plus rescue diet. The findings suggest that 1,25(OH)2D3 may be a promising protective intervention to reduce brain impairment induced by oxidative stress in the hypertension phenotype of 1α(OH)ase-/- mice.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"71 4","pages":"290-299"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144958069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Relationship between Children's Behavioral Characteristics and Eating Attitudes: A Cross-Sectional Study in Japanese Preschool Children. 儿童行为特征与饮食态度的关系：对日本学龄前儿童的横断面研究。

IF 0.7 4区医学

Journal of nutritional science and vitaminology Pub Date : 2025-01-01 DOI: 10.3177/jnsv.71.192

Hiroko Inoue, Yukina Morimoto, Ayako Hashimoto, Ikuko Nagaya, Noriko Kameyama, Kozue Nakamura, Toshiko Kuwano

{"title":"The Relationship between Children's Behavioral Characteristics and Eating Attitudes: A Cross-Sectional Study in Japanese Preschool Children.","authors":"Hiroko Inoue, Yukina Morimoto, Ayako Hashimoto, Ikuko Nagaya, Noriko Kameyama, Kozue Nakamura, Toshiko Kuwano","doi":"10.3177/jnsv.71.192","DOIUrl":"https://doi.org/10.3177/jnsv.71.192","url":null,"abstract":"We aimed to clarify the relationship between eating situations and behavioural problems in Japanese preschool children. Subjects were 591 children who attended nursery school in city Y, Japan, and their guardians. We administered a questionnaire that included the children's behavioural characteristics and items pertaining to eating situations, family structure, and guardian's educational background. We analysed the association between eating situations, meal greetings, pleasant mealtime, states of mastication, eating speed, and behavioural problems among preschool children. In these analyses, a Total Difficulty Score (TDS) was used to classify children's behavioural characteristics into two groups, 'Normal' and 'Borderline/Abnormal,' and binomial logistic regression analysis was performed. We calculated the odds ratio (OR) and 95% confidence interval (95% CI) for 'Borderline/Abnormal.' Children who rarely ate breakfast with their families had an adjusted OR of 10.59 for borderline/abnormal TDS compared to children who ate breakfast with their families four or more days a week (p=0.005). Children who chewed only a little at meals had an adjusted OR of 3.25 for borderline/abnormal TDS than children who chewed well. Furthermore, the children who answered that mealtimes were not pleasant mealtime had an adjusted OR of 3.01 for borderline/abnormal TDS than children who always had pleasant mealtime. The results of this study suggested that children's behavioural problems, based on their TDS classification, were related to their eating situations and eating behaviours.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"71 3","pages":"192-200"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dietary Patterns Rich in Soybean Products, Vegetables, Fish, Fruits, and Miso Soup Were Inversely Associated with Fatty Liver Index: The Nagahama Study. 富含豆制品、蔬菜、鱼、水果和味噌汤的饮食模式与脂肪肝指数呈负相关：永滨研究。

IF 0.7 4区医学

Journal of nutritional science and vitaminology Pub Date : 2025-01-01 DOI: 10.3177/jnsv.71.25

Yoko Ueba, Kaori Ikeda, Yasuharu Tabara, Takeo Nakayama, Daisuke Tanaka, Yoshimitsu Takahashi, Shinji Kosugi, Kazuya Setoh, Takahisa Kawaguchi, Fumihiko Matsuda, Nobuya Inagaki

{"title":"Dietary Patterns Rich in Soybean Products, Vegetables, Fish, Fruits, and Miso Soup Were Inversely Associated with Fatty Liver Index: The Nagahama Study.","authors":"Yoko Ueba, Kaori Ikeda, Yasuharu Tabara, Takeo Nakayama, Daisuke Tanaka, Yoshimitsu Takahashi, Shinji Kosugi, Kazuya Setoh, Takahisa Kawaguchi, Fumihiko Matsuda, Nobuya Inagaki","doi":"10.3177/jnsv.71.25","DOIUrl":"10.3177/jnsv.71.25","url":null,"abstract":"Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prominent liver disease occurring in approximately 25% of the general population. As treatment, lifestyle modification is essential, but there are few reports on dietary patterns associated with MASLD except for the Mediterranean diet. This study examines dietary habits related to MASLD using the fatty liver index (FLI). Longitudinal analysis of a community-based cohort, the Nagahama Prospective Cohort for Comprehensive Human Bioscience, was performed. Dietary habits were assessed by a self-reported questionnaire on food intake frequency, and factor analysis was applied to identify dietary patterns. Multiple regression analysis was performed with baseline FLI or FLI after 5 y as the dependent variable and sex, age, and/or baseline FLI, and factor scores of each dietary pattern as simultaneous independent variables. The same analyses stratified by sex or body mass index (BMI) were also performed. Three thousand five hundred one participants were included. The 15 food items of the questionnaire were summarized into four dietary patterns. Dietary patterns rich in soybean products, vegetables, fish, fruits, and miso soup, which is characteristic of traditional Japanese diet, negatively correlated with FLI and FLI after 5 y (partial regression coefficient: -3.01 and -1.03, respectively; p<0.01 for both). The result was similar in sex-specific analysis and in BMI<23 kg/m2 group, when the participants were stratified according to BMI. Our results suggest that dietary patterns rich in soybean products, vegetables, fish, fruits, and miso soup are protective factors against MASLD especially in individuals with BMI<23 kg/m2.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"71 1","pages":"25-33"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0