Journal of nutritional science and vitaminology最新文献_第10页

Optimal Body Weights for Adults with Severe Motor and Intellectual Disabilities. 严重运动障碍和智力障碍成人的最佳体重。

IF 0.7 4区医学

Journal of nutritional science and vitaminology Pub Date : 2024-01-01 DOI: 10.3177/jnsv.70.248

Osamu Uemura, Yuki Oshio, Yuka Hasegawa, Hideaki Nakashima, Kiyomi Hattori, Yoshihiro Otobe

{"title":"Optimal Body Weights for Adults with Severe Motor and Intellectual Disabilities.","authors":"Osamu Uemura, Yuki Oshio, Yuka Hasegawa, Hideaki Nakashima, Kiyomi Hattori, Yoshihiro Otobe","doi":"10.3177/jnsv.70.248","DOIUrl":"https://doi.org/10.3177/jnsv.70.248","url":null,"abstract":"Determining the optimal body weight for individuals with severe motor and intellectual disabilities (SMID) lacks a standardized approach. In this study, we aimed to develop a formula to estimate the ideal body weight for each SMID patient, considering factors such as reduced muscle and bone mass. We analyzed data from 111 SMID patients (56 male, 55 female; age range 20 to 73 y) who underwent blood tests measuring creatinine (Cr) and cystatin C (cysC) for clinical reasons between Feb. 2018 and Feb. 2023. To create the optimal body weight formula, we utilized three variables: height, estimated glomerular filtration (eGFR)-Cr, and eGFR-cysC. The validity of the formula was assessed by comparing the measured triceps subcutaneous fat thickness (TSF) to the reference TSF (%TSF), evaluating how accurately it reflects the appropriate physique. The derived optimal body weight formula is as follows: Optimal body weight=(height)2×(18.5-25.0)×{1-0.41×(1-eGFR-cysC/eGFR-Cr)}×0.93. Our formula demonstrated validity when using %TSF as an indicator. Establishing a method to determine optimal body weight in SMID patients, considering their low muscle and bone mass, is crucial for accurate nutritional assessment and subsequent nutritional management.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"70 3","pages":"248-251"},"PeriodicalIF":0.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141468734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Alaska Pollack Protein Ingestion on Neuromuscular Adaptation in Young Healthy Adults: A Randomized, Placebo-Controlled Trial. 摄入阿拉斯加鳕鱼蛋白质对健康年轻人神经肌肉适应性的影响：随机安慰剂对照试验。

IF 0.7 4区医学

Journal of nutritional science and vitaminology Pub Date : 2024-01-01 DOI: 10.3177/jnsv.70.228

Tetsuya Hirono, Saeko Ueda, Eriko Yoshida, Kenji Uchida, Aleš Holobar, Yukiko Mita, Kohei Watanabe

{"title":"Effects of Alaska Pollack Protein Ingestion on Neuromuscular Adaptation in Young Healthy Adults: A Randomized, Placebo-Controlled Trial.","authors":"Tetsuya Hirono, Saeko Ueda, Eriko Yoshida, Kenji Uchida, Aleš Holobar, Yukiko Mita, Kohei Watanabe","doi":"10.3177/jnsv.70.228","DOIUrl":"10.3177/jnsv.70.228","url":null,"abstract":"Alaska pollack protein (APP), has been reported as a protein source that can enhance muscle hypertrophy more than other protein sources in animal studies. This study aimed to examine the effects of APP ingestion on muscle quantity and quality in young adults. Fifty-five young college students were assigned to two groups: APP and placebo (whey protein: WP) groups, and instructed to ingest 4.5 g of each protein in addition to daily meals, and to maintain their usual daily physical activities for 3 mo. Twenty-one and 23 students completed the intervention and were analyzed in APP and WP groups, respectively. The maximum knee extension torque significantly increased in both groups during the intervention. The motor unit discharge rate, which is an indicator of activation, for a given force level significantly decreased in both groups during the intervention, but its decrease in the APP group was significantly greater than in the WP group. Echo intensity of the vastus lateralis evaluated by ultrasound images significantly decreased in both groups. The muscle thickness and skeletal muscle mass did not change. Small amount of additional APP intake induces greater effects on neural activation than WP, suggesting the greater neural economy of generation of force.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"70 3","pages":"228-236"},"PeriodicalIF":0.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141468771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nutritional Imbalance between Omega-6 and Omega-3 Polyunsaturated Fatty Acids during Pregnancy Increases the Number of Pyramidal Neurons in the Basolateral Amygdala and Anxiety-Related Behavior in Offspring. 孕期奥米加 6 和奥米加 3 多不饱和脂肪酸之间的营养失衡会增加基底外侧杏仁核中锥体神经元的数量和后代的焦虑相关行为。

IF 0.7 4区医学

Journal of nutritional science and vitaminology Pub Date : 2024-01-01 DOI: 10.3177/jnsv.70.411

Taro Kikuchi, Daigo Omokawa, Masanori Katakura, Miho Matsumata, Hidenori Aizawa, Makoto Sugita, Nobuyuki Sakayori

{"title":"Nutritional Imbalance between Omega-6 and Omega-3 Polyunsaturated Fatty Acids during Pregnancy Increases the Number of Pyramidal Neurons in the Basolateral Amygdala and Anxiety-Related Behavior in Offspring.","authors":"Taro Kikuchi, Daigo Omokawa, Masanori Katakura, Miho Matsumata, Hidenori Aizawa, Makoto Sugita, Nobuyuki Sakayori","doi":"10.3177/jnsv.70.411","DOIUrl":"https://doi.org/10.3177/jnsv.70.411","url":null,"abstract":"Modern agriculture allows for the production of foods that are high in n-6 linoleic acid and low in n-3 α-linolenic acid (LAhigh/ALAlow), which are suggested to be associated with an increased risk for the onset of anxiety disorders. However, there is not sufficient evidence to understand its underlying brain mechanism. Given that mouse offspring derived from mothers fed a LAhigh/ALAlow diet during gestation and early lactation showed increased anxiety-related behaviors and that rodents exposed to a LAhigh/ALAlow diet are more vulnerable to stress, in this study, we investigated the effects of maternal LAhigh/ALAlow diet consumption on stress-induced anxiety-related behavior and the brain structures involved in the expression of negative emotional states in mouse offspring. In a standard environment, offspring exposed to either the control diet or the LAhigh/ALAlow diet in utero showed similar stay times in the center zone in the open field test. On the other hand, under stressful environments, offspring exposed to the LAhigh/ALAlow diet in utero showed decreased stay times in the center zone compared to those exposed to the control diet. We further found that the number of a subpopulation of pyramidal neurons in the basolateral amygdala, which can regulate negative emotional behaviors, was greater in the offspring exposed to the LAhigh/ALAlow diet compared to those exposed to the control diet. These data suggest that maternal dietary imbalance between n-6 and n-3 polyunsaturated fatty acids confers stress vulnerability to offspring during the process of brain development.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"70 5","pages":"411-421"},"PeriodicalIF":0.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142546036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing Nutritional Status and Addressing Micronutrient Deficiencies: Evaluating the Impact of Workplace Nutrition Program on Female Workers in Vietnam. 改善营养状况，解决微量营养素缺乏问题：评估工作场所营养计划对越南女工的影响》（Evaluating the Impact of Workplace Nutrition Program on Female Workers in Vietnam）。

IF 1.6 4区医学

Journal of nutritional science and vitaminology Pub Date : 2024-01-01 DOI: 10.3177/jnsv.70.131

Linh Thuy Nguyen, Khanh Do Nam, Phuong Thi Duong, Tuyet Chinh Thi Pham, Yoshinori Komatsu

{"title":"Enhancing Nutritional Status and Addressing Micronutrient Deficiencies: Evaluating the Impact of Workplace Nutrition Program on Female Workers in Vietnam.","authors":"Linh Thuy Nguyen, Khanh Do Nam, Phuong Thi Duong, Tuyet Chinh Thi Pham, Yoshinori Komatsu","doi":"10.3177/jnsv.70.131","DOIUrl":"10.3177/jnsv.70.131","url":null,"abstract":"This randomized controlled clinical study aimed to assess the effectiveness of a nutrition intervention program for non-pregnant female workers in Vietnam. A total of 500 female workers were randomly assigned to the intervention and control groups. Participants in the intervention group were provided nutrition education, personalized specific dietary, and received oral nutrition supplements (ONS)-which contained multi-minerals and vitamins according to recommendations for adults for a duration of 12 wk, while participants in the control group received only nutrition education. The result shows the percentage of malnutrition by BMI in the control group rose from 15.6% to 21.3% after 12 wk; the figure for counterpart experienced a remain unchanged (p<0.05). Additionally, the mean of serum zinc in the intervention group significantly increased from 49.0±21.2 μg/dL to 53.6±19.5 μg/dL after 12 wk. Moreover, the intervention group demonstrated significant increases in serum iron and total serum calcium levels (p<0.05), with from 13.9±5.6 μmol/L to 15.3±5.8 μmol/L, and from 2.36±0.15 mmol/L to 2.4±0.09 mmol/L, respectively. The participants of the intervention group were more likely to have higher total serum calcium (Coef=0.04, p<0.05), serum iron (Coef=1.99, p<0.05), and serum zinc (Coef=18.9, p<0.05), which presents a reduce micronutrient deficiency. In conclusion, workplace nutrition interventions effectively mitigate micronutrient deficiencies and improve the nutritional status of female workers.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"70 2","pages":"131-138"},"PeriodicalIF":1.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140870513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Consumption of Fructooligosaccharides Influences the Action of Fecal MicroRNAs in Altering the Structure of Cultured Gut Microbiota in Mice. 食用果寡糖会影响粪便微RNA在改变小鼠培养肠道微生物群结构中的作用

IF 0.7 4区医学

Journal of nutritional science and vitaminology Pub Date : 2024-01-01 DOI: 10.3177/jnsv.70.387

Fumina Ohsaka, Moeka Yasui, Mayuko Yamaguchi, Kei Sonoyama

{"title":"Consumption of Fructooligosaccharides Influences the Action of Fecal MicroRNAs in Altering the Structure of Cultured Gut Microbiota in Mice.","authors":"Fumina Ohsaka, Moeka Yasui, Mayuko Yamaguchi, Kei Sonoyama","doi":"10.3177/jnsv.70.387","DOIUrl":"https://doi.org/10.3177/jnsv.70.387","url":null,"abstract":"Fecal microRNAs (miRNAs) derived from intestinal epithelial cells have been suggested to influence gut microbiota homeostasis. We recently showed that supplementing murine fecal small RNAs, most likely miRNAs, alters the structure of cultured fecal microbiota in a sequence-dependent manner. The present study investigated the effect of consuming fructooligosaccharides (FOS) on the action of fecal small RNAs in altering the structure of cultured fecal microbiota. Female C57BL/6J mice were allowed free access to AIN-93G diet, and tap water supplemented with or without 4% (w/v) FOS for 2 wk. As assessed by 16S rRNA gene sequence analysis in cecal contents, the gut microbiota structure differed between mice supplemented with and without FOS. Fecal bacteria isolated from the cecal contents of mice without FOS supplementation were cultured for 24 h under anaerobic conditions. The structure of cultured microbiota differed between the cultures supplemented with small RNAs isolated from the cecal contents of mice supplemented with and without FOS. Microarray analysis showed that the miRNA profile in the cecal contents differed between mice supplemented with and without FOS. We propose that FOS consumption influences the action of intestinal epithelial cell-derived miRNAs in altering the structure of cultured gut microbiota, and such FOS action is associated with changes in the profile of miRNAs. It may be possible that intestinal epithelial cell-derived miRNAs contribute, at least in part, to diet-induced alteration of gut microbiota.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"70 5","pages":"387-395"},"PeriodicalIF":0.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142546019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dietary Supplementation of Vitamin B₁₂ to Rats Fed High-Amylose Cornstarch Normalizes Propionate Fermentation in the Colon. 给喂食高木糖玉米淀粉的大鼠补充维生素 B12 可使大肠中的丙酸发酵正常化。

IF 1.6 4区医学

Journal of nutritional science and vitaminology Pub Date : 2024-01-01 DOI: 10.3177/jnsv.70.139

Tomoki Umeda, Chihiro Yamada, Takahiro Kawase, Takamitsu Tsukahara, Ryo Inoue, Shingo Hino, Naomichi Nishimura

{"title":"Dietary Supplementation of Vitamin B12 to Rats Fed High-Amylose Cornstarch Normalizes Propionate Fermentation in the Colon.","authors":"Tomoki Umeda, Chihiro Yamada, Takahiro Kawase, Takamitsu Tsukahara, Ryo Inoue, Shingo Hino, Naomichi Nishimura","doi":"10.3177/jnsv.70.139","DOIUrl":"https://doi.org/10.3177/jnsv.70.139","url":null,"abstract":"Since propionate exerts several physiological effects, maintenance of its normal colonic fermentation is essential. To investigate whether vitamin B12 (VB12) is essential for normal propionate fermentation by colonic bacteria, via the succinate pathway, we examined if high-amylose cornstarch (HACS) feeding activated such a pathway, if high HACS feeding impaired propionate fermentation, and if oral VB12 supplementation normalized propionate fermentation. Male rats were given control, 20% HACS or 3% fucose diets (Expt. 1); a VB12-free control diet or one supplemented with 5-30% HACS (Expt. 2); and the 20% HACS diet supplemented with 0.025-25 mg/kg of VB12 (Expt. 3), for 14 d. HACS feeding significantly increased cecal succinate concentration, activating the succinate pathway (Expt. 1). Cecal cobalamin concentration in 20% and 30% HACS groups was about 75% of that in the control group (Expt. 2). Cecal succinate and propionate concentrations significantly increased and decreased in 30% HACS groups, respectively, compared with the control group. Although HACS group supplemented with 0.025 mg/kg of VB12 had a low concentration of cecal propionate, adding high amounts of VB12 to HACS diets provided sufficient amounts of VB12 to rat ceca and increased cecal propionate concentration (Expt. 3). Compared with the non-HACS group, the relative abundance of Akkermansia muciniphila, but not Bacteroides/Phocaeicola, was lower in the HACS counterpart and showed improvement with increased VB12 doses. To summarize, feeding high HACS decreased and increased cecal VB12 and succinate concentrations, respectively. Furthermore, colonic delivery of sufficient amounts of VB12 to rats likely reduced accumulation of succinate and normalized propionate fermentation.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"70 2","pages":"139-149"},"PeriodicalIF":1.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140861490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Immature Soybeans on Lipid Metabolism in Rats Fed Normal and High-Fat High-Fructose NAFLD Diets. 未成熟大豆对正常膳食和高脂肪高果糖非酒精性脂肪肝膳食大鼠脂质代谢的影响

IF 0.7 4区医学

Journal of nutritional science and vitaminology Pub Date : 2024-01-01 DOI: 10.3177/jnsv.70.370

Takafumi Mizushige, Tomohiro Suzuki, Tadayoshi Utsuki, Yuna Ishikawa, Kirara Ogawa, Chinatsu Kanamaru, Sayo Shoji, Dai Nogimura, Haruna Aiso, Eriko Yoshida, Kenji Uchida, Yukihito Kabuyama

{"title":"Effects of Immature Soybeans on Lipid Metabolism in Rats Fed Normal and High-Fat High-Fructose NAFLD Diets.","authors":"Takafumi Mizushige, Tomohiro Suzuki, Tadayoshi Utsuki, Yuna Ishikawa, Kirara Ogawa, Chinatsu Kanamaru, Sayo Shoji, Dai Nogimura, Haruna Aiso, Eriko Yoshida, Kenji Uchida, Yukihito Kabuyama","doi":"10.3177/jnsv.70.370","DOIUrl":"https://doi.org/10.3177/jnsv.70.370","url":null,"abstract":"Edamame and chamame (brown edamame) are immature soybeans that contain abundant protein, vitamins, and dietary fiber. Edamame has a different nutrient composition compared with mature soybeans, as evidenced by its higher content of vitamins and folic acid. Recent studies have shown that proteins in mature soybeans, such as β-conglycinin, and dietary fiber influence the metabolism of lipids such as triglyceride and cholesterol. However, the effect of edamame on lipid metabolism has not been reported. In the present study, we investigated whether oral consumption of edamame or chamame affects lipid metabolism. We focused on the analysis of hepatic lipids, serum cholesterol, and fecal lipids in rats after feeding them a normal or non-alcoholic fatty liver disease (NAFLD) diet containing edamame or chamame for 6 wk. We found that the consumption of dietary edamame and chamame significantly lowered hepatic triglyceride and serum cholesterol levels compared with those in the control groups fed with normal and NAFLD diets. Intake of edamame and chamame improved the NAFLD-like fatty liver. Finally, intake of edamame and chamame resulted in a significantly higher amount of fecal lipids and bile acid than in the control, suggesting the stimulation of lipid excretion. Together, dietary edamame and chamame decrease hepatic and serum cholesterol by promoting lipid excretion, not by the regulation of hepatic gene expression, leading to the improvement of lipid metabolism in both normal and NAFLD model rats.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"70 5","pages":"370-379"},"PeriodicalIF":0.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142546034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anti-Obesity Effects of a Combination of Whole-Body Vibration Stimulus and Dietary D-Allulose on Rats Fed a High-Fat Diet. 全身振动刺激和膳食D-Allulose联合对高脂饮食大鼠的抗肥胖作用。

IF 0.7 4区医学

Journal of nutritional science and vitaminology Pub Date : 2024-01-01 DOI: 10.3177/jnsv.70.508

Shunsuke Higaki, Reiko Inai, Susumu Mochizuki, Akihide Yoshihara, Kazuya Akimitsu, Tatsuhiro Matsuo

{"title":"Anti-Obesity Effects of a Combination of Whole-Body Vibration Stimulus and Dietary D-Allulose on Rats Fed a High-Fat Diet.","authors":"Shunsuke Higaki, Reiko Inai, Susumu Mochizuki, Akihide Yoshihara, Kazuya Akimitsu, Tatsuhiro Matsuo","doi":"10.3177/jnsv.70.508","DOIUrl":"https://doi.org/10.3177/jnsv.70.508","url":null,"abstract":"Whole-body vibration (WBV) has gained attention as a light-resistance exercise and can increase energy metabolism. The rare sugar D-allulose has anti-obesity effects that are mediated by the suppression of hepatic lipogenesis. In this study, we examined the anti-obesity effects of a combination of WBV and dietary D-allulose in rats fed a high-fat diet. Thirty-two male Wistar rats (3-wk-old) were randomly assigned to four groups: sedentary control (C), WBV (V), D-allulose (A), and WBV+D-allulose (VA). Rats in Groups A and VA were fed a 5% D-allulose diet, and rats in Groups V and VA were subjected to WBV using a vibrating platform during the 8-wk experimental period. Total abdominal adipose tissue was significantly lower in Groups V, A, and VA than that in Group C, whereas no differences were observed between Groups V, A, and VA. Dietary D-allulose significantly decreased the weights and percentages of carcass and total body fats, whereas the WBV stimulus significant reduced only the total body fat mass. We observed that both long-term WBV stimulation and dietary D-allulose intake inhibited body fat accumulation in rats fed a high-fat diet, which led to obesity; however, no synergistic effect of this combination could be confirmed.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"70 6","pages":"508-513"},"PeriodicalIF":0.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142932043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Intake of Dietary Lipids Improves Glucose Tolerance via Modulating Gut Microbiota. 摄入膳食脂质可通过调节肠道微生物群改善葡萄糖耐受性

IF 0.7 4区医学

Journal of nutritional science and vitaminology Pub Date : 2024-01-01 DOI: 10.3177/jnsv.70.336

Yuri Haneishi, Saya Watanabe, Ayana Okada, Hitoshi Takemae, Deborah Bastoni, Lucia Treppiccione, Anella Saggese, Tetsuya Mizutani, Mauro Rossi, Junki Miyamoto

{"title":"The Intake of Dietary Lipids Improves Glucose Tolerance via Modulating Gut Microbiota.","authors":"Yuri Haneishi, Saya Watanabe, Ayana Okada, Hitoshi Takemae, Deborah Bastoni, Lucia Treppiccione, Anella Saggese, Tetsuya Mizutani, Mauro Rossi, Junki Miyamoto","doi":"10.3177/jnsv.70.336","DOIUrl":"https://doi.org/10.3177/jnsv.70.336","url":null,"abstract":"The composition of gut microbiota is determined not only by genetic factors but also by environmental factors, such as diet, exercise, and disease conditions. Among these factors, diet is crucial in changing the gut microbial composition. Dietary lipids composed of different fatty acids not only alter host metabolism but also have a significant impact on the composition of gut microbiota. However, the molecular mechanisms underlying the relationship between these host effects and their impact on gut microbiota remain unclear. Here, we demonstrated that intake of different dietary lipids improved glucose tolerance by modulating gut microbiota. The results of our analysis show that the taxa of bacteria that increase in number as a result of dietary lipid intake play an important role in glucose metabolism. Thus, we have identified a new mechanism underlying the function of dietary lipids in regulating glucose homeostasis. Our findings contribute to possible new methods to prevent and treat metabolic disorders by modifying the composition of gut microbiota.","PeriodicalId":16624,"journal":{"name":"Journal of nutritional science and vitaminology","volume":"70 4","pages":"336-343"},"PeriodicalIF":0.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142108379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Behavioral Dysfunctions Caused by Pyridoxamine Deficiency in Drosophila melanogaster. 黑腹果蝇缺乏吡哆胺导致的行为障碍

IF 0.7 4区医学

Journal of nutritional science and vitaminology Pub Date : 2024-01-01 DOI: 10.3177/jnsv.70.252

Kohei Ueno, Izumi Nohara, Mitsuhiro Miyashita, Masanari Itokawa, Haruo Okado, Makoto Arai, Minoru Saitoe

引用次数: 0