{"title":"Towards Optimized Awake Bruxism Metrics: Empirical Definition of Minimal Ecological Momentary Assessment Requirements","authors":"Alona Emodi-Perlman, Lihi Keren, Anna-Yael Czygrinow, Khalil Masarwe, Noa Ventura, Ilana Eli","doi":"10.1111/joor.70263","DOIUrl":"10.1111/joor.70263","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Ecological Momentary Assessment (EMA) is increasingly used to assess awake bruxism (AB) in real time. However, current protocols typically require 7 days of monitoring and high daily response rates, potentially limiting compliance.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To empirically establish the shortest monitoring duration and daily response threshold that still yield reliable estimates of AB behaviours through smartphone-based EMA.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Data from three EMA studies were pooled, yielding 327 participants who completed smartphone-based monitoring. Five core AB behaviours (relaxed jaw muscles, bracing, teeth contact, clenching, and grinding) were analysed. Temporal stability was evaluated using intraclass correlation coefficients (ICC[A,1]) by comparing progressively shorter monitoring windows with the complete 7-day dataset. Compliance-threshold analyses examined the relationship between minimum daily responses, reliability, and participant retention.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The pooled dataset included over 32 000 EMA reports. Relaxed jaw condition was the most frequently reported behaviour (52.2%), followed by teeth contact (18.6%) and bracing (14.5%). Clenching (6.9%) and grinding (1.4%) were less frequent. Four of five behaviours achieved excellent stability after three monitoring days (ICC ≥ 0.86), whereas grinding reached stability after 2 days (ICC = 0.81). Increasing the minimum daily response threshold improved reliability but substantially reduced sample retention. A threshold of ≥ 12 answered alerts/day provided the best balance between reliability and retention.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Reliable assessment of the five core awake bruxism behaviours can be achieved using a 3-day EMA protocol with at least 12 answered alerts/day. These findings support a reduction in monitoring burden while maintaining data quality.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16605,"journal":{"name":"Journal of oral rehabilitation","volume":"53 11","pages":"2112-2119"},"PeriodicalIF":3.8,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/joor.70263","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148421701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jiannan Zhao, Yao Liu, Xingyu Lyu, Ruiye Bi, Nan Jiang, Xiaoqing Li, Xiaodong Li, Abotaleb Bassam, Songsong Zhu, Pinyin Cao
{"title":"Surgical and Conservative Treatment of Temporomandibular Joint Anterior Disc Displacement in Adults: A Cohort Study on Condylar Remodelling","authors":"Jiannan Zhao, Yao Liu, Xingyu Lyu, Ruiye Bi, Nan Jiang, Xiaoqing Li, Xiaodong Li, Abotaleb Bassam, Songsong Zhu, Pinyin Cao","doi":"10.1111/joor.70240","DOIUrl":"10.1111/joor.70240","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Surgical and conservative treatments are primary options for anterior disc displacement without reduction (ADDWoR) of the temporomandibular joint. However, their long-term effects on condylar remodelling remain unclear. This study aimed to investigate and compare the long-term effects of both strategies on condylar remodelling.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>After being informed of both treatment options, patients with ADDWoR independently selected either disc repositioning surgery or conservative treatment with intra-articular injections combined with stabilization splints. CBCT scans were obtained at baseline and 12 months post-treatment. Quantitative assessments included condylar height, length and width, anterior joint space and condylar degenerative scores, with condylar height as the primary outcome. Postoperative condylar changes were evaluated qualitatively.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The surgical group included 91 patients (129 joints) and the conservative group 102 patients (139 joints). At 12 months, mean condylar height increased by 0.24 mm in the surgical group but decreased by 0.89 mm in the conservative group. Most condyles were classified as “stable” or “improved” in the qualitative evaluation of condylar bone changes (surgical group: 86.0%; conservative group: 71.9%). Notably, among young adult patients with pre-existing degenerative condylar changes, 61.9% of condyles showed improvement after surgery compared to 28.1% in the conservative group. Surgical intervention also led to a greater reduction in condylar degenerative scores in this subgroup.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Both surgical and conservative treatments promoted favourable condylar remodelling in patients with ADDWoR. Surgery was associated with preservation or a slight increase in condylar height, whereas conservative treatment resulted in a slight height reduction. Furthermore, among young adult patients with pre-existing condylar degeneration, surgical intervention demonstrated greater improvement in degenerative changes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>ClinicalTrials.gov: ISRCTN99353996</p>\u0000 </section>\u0000 </div>","PeriodicalId":16605,"journal":{"name":"Journal of oral rehabilitation","volume":"53 11","pages":"2029-2040"},"PeriodicalIF":3.8,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148549493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dominie Yu, Renata Mancopes, Hilary Milne, Melanie Peladeau-Pigeon, Keara Boyce, Harmonie Chan, Maureen Folsom, Sophia Werden Abrams, Ashwini M. Namasivayam-MacDonald, Emily K. Plowman, Catriona M. Steele
{"title":"The Dynamics of Pharyngeal Shortening in Healthy Swallowing: Effects of Sex, Age, Bolus Volume and Consistency","authors":"Dominie Yu, Renata Mancopes, Hilary Milne, Melanie Peladeau-Pigeon, Keara Boyce, Harmonie Chan, Maureen Folsom, Sophia Werden Abrams, Ashwini M. Namasivayam-MacDonald, Emily K. Plowman, Catriona M. Steele","doi":"10.1111/joor.70257","DOIUrl":"10.1111/joor.70257","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Pharyngeal shortening is thought to facilitate bolus clearance through the pharynx and upper oesophageal sphincter (UES) in swallowing. However, little information is available regarding pharyngeal shortening in healthy swallowing.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective(s)</h3>\u0000 \u0000 <p>We characterised the timing and extent of pharyngeal shortening by tracking the height of the UES across key time points in healthy swallowing. Additionally, we identified variations in pharyngeal shortening attributable to participant (sex, age) and bolus factors (consistency, volume).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Videofluoroscopy data for (1) sips of thin liquid and (2) teaspoons of mildly thick liquid were analysed from 80 healthy adults (40 males, 40 females), distributed across four age groups: 18–35, 36–53, 54–72, 73–90 years. UES height was tracked relative to the cervical spine on the frames of UES opening (UESO), maximum UES height (UESMaxHeight) and swallow rest (SR) using a 20-point ordinal scale. Statistical analyses explored effects of sex, age-group, and task on: (1) latency-to-UESMaxHeight, (2) UES height at UESO and SR, and (3) the degree of pharyngeal shortening at UESMaxHeight relative to UESO and SR.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Maximum UES height occurred between the events of UES opening and closure, in close proximity to other biomechanically linked events. UES height was lower in males. Greater pharyngeal shortening was seen in males and on thin liquid tasks.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>These findings refine our understanding of healthy swallowing dynamics and highlight the influence of sex-linked differences in height on UES position relative to the cervical spine.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>ClinicalTrials.gov: NCT05497219</p>\u0000 </section>\u0000 </div>","PeriodicalId":16605,"journal":{"name":"Journal of oral rehabilitation","volume":"53 11","pages":"2082-2089"},"PeriodicalIF":3.8,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/joor.70257","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148396824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Henriette I. U. Stasche, Gina M. Georgi, Antje Körner, Wieland Kiess, Ronald Biemann, Jens C. Türp, Christian Hirsch
{"title":"Oral Contraceptive Use Is Associated With Increased Tenderness to Palpation in the Masticatory System in Female Adolescents—Results of the Epidemiological LIFE Child Study","authors":"Henriette I. U. Stasche, Gina M. Georgi, Antje Körner, Wieland Kiess, Ronald Biemann, Jens C. Türp, Christian Hirsch","doi":"10.1111/joor.70270","DOIUrl":"10.1111/joor.70270","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The utilisation of oral contraceptives (OCs) has been demonstrated to be associated with the self-reported occurrence of headaches in female adolescents. The objective of the present study was to determine whether the ingestion of OC was also associated with increased tenderness to calibrated palpation of the masticatory system.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A subsample of 111 female adolescents aged between 14 and 18 years from the LIFE Child study who were undergoing a general (with blood sample) and dental examination were included in the investigation. The presence of self-reported headaches in the past month, as well as tenderness to calibrated palpation of the masticatory muscles and the temporomandibular joints (TMJs), was evaluated using the DC/TMD. The determination of oestrogen (E), testosterone (T), and the sexual hormone binding globulin (SHBG) was conducted through standardised laboratory analyses. In the statistical analyses, calculations were made employing logistic regression for comparisons regarding the risk experienced by female adolescents of positive tenderness to palpation and self-reported headaches as a function of OC use. The analysis also incorporated consideration of age and body mass index (BMI).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The prevalence of regular OC use among female adolescents was found to be 26 out of 111 (23.4%). A subsequent analysis revealed no statistically significant disparities in age or BMI when compared to non-users. OC use was associated with a fivefold reduction in E, a 50% reduction in T and a threefold increase in SHBG. The prevalence of self-reported headaches and tenderness to palpation in the masticatory system was found to be significantly higher in the OC group. In the multivariable models, these relationships were confirmed, regardless of age and BMI as potential confounding factors. For self-reported headaches, OC presented a coefficient of around six and approximately three for tenderness to palpation. Age was an additional significant factor in tenderness to palpation (OR ≈ 1.7); this correlation was not observed in cases of headaches.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The use of OC has been demonstrated to enhance the likelihood of encountering self-reported headaches and increased tenderness to palpation within the masticatory system in female adolescents. Consequently, the utilisation of OC in female adolescents with temporomandibular disorders warrants further consideration.</p>\u0000 </section","PeriodicalId":16605,"journal":{"name":"Journal of oral rehabilitation","volume":"53 11","pages":"2158-2165"},"PeriodicalIF":3.8,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/joor.70270","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148549511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Miira M. Vehkalahti, Kaija Hiltunen, Maria Valaste
{"title":"Volume of Treatment of Temporomandibular Disorders in Adults—A Nationwide Register-Based Observation of Private Oral Healthcare in Finland in 2006–2024","authors":"Miira M. Vehkalahti, Kaija Hiltunen, Maria Valaste","doi":"10.1111/joor.70272","DOIUrl":"10.1111/joor.70272","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Temporomandibular disorders (TMD) present diverse signs and symptoms and often require clinical evaluation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To investigate variation in the volume of TMD treatment among adult patients in Finnish private oral healthcare between 2006 and 2024.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This retrospective register-based study used annual aggregate data from the Social Insurance Institution of Finland on patients aged 20 years or older. Per year, an average of 56 500 patients received TMD-related procedures, which were primarily coded by visit duration; only splint therapy was coded as a single, specific procedure. TMD treatment volume was described as the number and proportion of TMD patients and procedures, overall in each year from 2006 to 2024 and in detail, by 5-year age groups in selected years (2012, 2014, 2017, 2020, 2022 and 2024). Linear regression assessed associations between treatment year, age group and treatment volume.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>From 2006 to 2024, TMD patients constituted 4.1%–6.7% of all patients, peaking in 2015–2019 and in age groups 25–55 years. TMD procedures accounted for 1.2% of all clinical procedures in 2006, 2.4% in 2020 and 2.0% in 2024. Short- and medium-duration TMD procedures predominated; splint therapy was more common in younger patients (in 2024, 28%–32% of TMD patients aged 20–39 years and 25%–27% aged 40–54 years). Linear regression showed strong, negative associations between age group and TMD treatment volume (<i>p</i> < 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>TMD therapy is more common among younger adults. Register-based data indicate increasing use of splint therapy, particularly among younger patients. Recent declines in overall volume after peak years may reflect changes in clinical decision-making and promote a more nuanced understanding of treatment risks.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16605,"journal":{"name":"Journal of oral rehabilitation","volume":"53 11","pages":"2166-2172"},"PeriodicalIF":3.8,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/joor.70272","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148447542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of Digital Health Interventions on Pain, Maximum Mouth Opening, and Jaw Function in Individuals With Temporomandibular Disorders: A Systematic Review","authors":"Kailing Xu, Lanqi Li, Yinuo He, Fangyuan Jing, Jingxia Kong, Minmin Jiang","doi":"10.1111/joor.70291","DOIUrl":"10.1111/joor.70291","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Temporomandibular disorders (TMD) encompass a group of musculoskeletal and neuromuscular conditions involving the temporomandibular joint (TMJ), masticatory muscles, and associated structures. As an emerging self-management approach, digital health interventions (DHIs) have demonstrated potential clinical value.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To investigate the effects of DHIs on pain, maximum mouth opening, and jaw function in individuals with TMD.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A literature search was performed in five electronic databases: PubMed, Web of Science, Embase, Cochrane Library, and MEDLINE, with the search date set to 18 January 2026. Inclusion criteria comprised randomised controlled trials (RCTs) evaluating DHIs for individuals with TMD that reported pain, jaw function, and maximum mouth opening (MMO) as primary outcomes. Risk of bias was assessed using the Risk of Bias 2 tool for all included studies. The certainty of evidence for each outcome was assessed using the GRADE approach. A narrative synthesis of the findings was subsequently performed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Six eligible RCTs were included, totaling 352 participants. The review assessed the effects of three types of DHIs, including mobile applications, internet-based behavioural therapy (IBT), and telerehabilitation, for individuals with TMD. Under the descriptive umbrella of this narrative synthesis, mobile applications and telerehabilitation may be associated with improvements in pain, jaw function, and MMO. The certainty of evidence was rated as very low per GRADE criteria. No such benefits have yet been identified for IBT.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>DHIs may be beneficial in reducing pain, increasing mouth opening, and improving jaw function in individuals with TMD. However, further high-quality research is warranted to confirm these findings.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>PROSPERO Registration Number: CRD420261304970</p>\u0000 </section>\u0000 </div>","PeriodicalId":16605,"journal":{"name":"Journal of oral rehabilitation","volume":"53 11","pages":"2173-2189"},"PeriodicalIF":3.8,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148850877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yoohyun Sim, Na-Yeon Ha, Seok-Jae Ko, Jae-Woo Park, Jinsung Kim
{"title":"Comparative Study of Clinical Characteristics According to Pain Distribution in Lingual Burning Mouth Syndrome","authors":"Yoohyun Sim, Na-Yeon Ha, Seok-Jae Ko, Jae-Woo Park, Jinsung Kim","doi":"10.1111/joor.70269","DOIUrl":"10.1111/joor.70269","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The pathophysiology of burning mouth syndrome (BMS) remains unclear.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To compare the clinical characteristics of patients with lingual BMS according to pain distribution.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The medical records of patients with lingual BMS who visited the oral clinic of Kyung Hee University Korean Medicine Hospital between January 2023 and December 2024 were retrospectively reviewed. Patients were classified according to tongue pain distribution as follows: laterality (unilateral vs. bilateral), extent (localised vs. generalised) and central tongue involvement (non-central vs. central involvement). Group differences and associations among clinical characteristics, including pain intensity (visual analog scale [VAS]), quality of life, salivary flow and taste disturbance, were assessed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In total, 256 patients were included. Patients with bilateral pain showed significantly higher pain intensity than those with unilateral pain. Patients with generalised pain reported significantly higher pain intensity than those with localised pain. Patients with central involvement showed significantly higher pain intensity than those with non-central involvement. Pain intensity was negatively associated with quality of life in most subgroups, except the unilateral subgroup. Taste disturbance was associated with clinically significant pain (VAS ≥ 4) in the unilateral and localised subgroups, whereas reduced salivary flow was associated with clinically significant pain in the central involvement subgroup.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Pain distribution may help identify clinical subtypes of lingual BMS and support individualised assessment. Herein, pain distribution was associated with differences in pain intensity, quality of life, taste disturbance and salivary flow, underscoring the heterogeneous and multifactorial pathophysiology of lingual BMS and the need for tailored management.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16605,"journal":{"name":"Journal of oral rehabilitation","volume":"53 11","pages":"2150-2157"},"PeriodicalIF":3.8,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/joor.70269","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148456089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adrian Ujin Yap, Abd Aziz Alias, Siew Wui Chan, Kathreena Kadir, Zuraiza Mohamad Zaini
{"title":"Psychosocial–Behavioural Phenotypes and Temporomandibular Disorder Risk: Insights From a Latent Class Analysis in Southeast Asian Young Adults","authors":"Adrian Ujin Yap, Abd Aziz Alias, Siew Wui Chan, Kathreena Kadir, Zuraiza Mohamad Zaini","doi":"10.1111/joor.70267","DOIUrl":"10.1111/joor.70267","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Psychosocial and behavioural factors shape temporomandibular disorders (TMDs), yet integrated phenotyping in Southeast Asian young adults remains limited. University students, a vulnerable subgroup of young adults, face heightened risk.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To identify latent psychosocial–behavioural classes in this cohort and assess associations with sociodemographic factors and TMD severity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A cross-sectional study of participants aged 18–30 years used validated instruments to assess distress (Patient Health Questionnaire-4; PHQ-4), somatic symptoms (PHQ-15), oral behaviours (Oral Behaviours Checklist; OBC), and TMDs (Short-form Fonseca Anamnestic Index; SFAI). Latent class analysis (LCA) was performed on PHQ-4, PHQ-15, and OBC scores, estimating one- to five-class models. Class differences were tested using <i>χ</i><sup>2</sup> and Kruskal–Wallis/Dunn's procedures. Predictors of class membership were evaluated using multinomial logistic regression (<i>α</i> = 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Three classes emerged: Resilient (56.1%), Moderate-Vulnerability (30.4%), and High-Risk (13.5%). TMD prevalence was highest in High-Risk (45.0%), intermediate in Moderate-Vulnerability (25.6%), and lowest in Resilient (10.0%). Depression (OR = 12.34), anxiety (OR = 13.03), somatic burden (OR = 4.91), and oral behaviours (sleeping-state OR = 1.77; waking-state non-functional OR = 1.70; waking-state functional OR = 1.44) significantly predicted High-Risk membership. Sociodemographic factors and TMD severity differentiated classes descriptively but lacked predictive strength.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>LCA delineated three psychosocial–behavioural phenotypes, with depression, anxiety, and somatic burden most strongly defining High-Risk membership, and oral behaviours adding incremental risk. Findings underscore upstream psychosocial–behavioural determinants as key prevention targets, while downstream outcomes guide tailored interventions in young adults.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16605,"journal":{"name":"Journal of oral rehabilitation","volume":"53 11","pages":"2140-2149"},"PeriodicalIF":3.8,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148578967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bernardo Correia Lima, Rayan Eboli Fortunato, Leonardo Brígido Metello Neves, Ricardo Grillo, Mariana Aparedida Brozoski, Fernando Melhem-Elias, Janey Prodoehl, Louis G. Mercuri
{"title":"Understanding Diagnostic Failure in Temporomandibular Disorders: A Narrative Synthesis of Evidence and Five-Domain Framework for Iatrogenic Mismanagement","authors":"Bernardo Correia Lima, Rayan Eboli Fortunato, Leonardo Brígido Metello Neves, Ricardo Grillo, Mariana Aparedida Brozoski, Fernando Melhem-Elias, Janey Prodoehl, Louis G. Mercuri","doi":"10.1111/joor.70294","DOIUrl":"10.1111/joor.70294","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Diagnostic errors in temporomandibular disorders (TMDs) contribute to unnecessary procedures and avoidable patient mismanagement despite advances in pain science, diagnostic classification systems, and evidence-based care.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To conduct a narrative review and present a dynamic, five-domain framework explaining how diagnostic uncertainty interacts with educational, cognitive, systemic, and ethical factors to produce iatrogenic overtreatment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Searches of PubMed, Scopus, Web of Science, and Google Scholar (inception to April 2026) identified literature on TMD diagnosis, clinical reasoning, dental education, health system organization, and bioethics. Concepts were synthesized into interacting thematic domains.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Five dynamic, interacting domains were identified: (1) Educational Deficits, (2) Structural Reductionism, (3) Occlusal Overinterpretation, (4) System Fragmentation, and (5) Ethical Dissonance. The model demonstrates how educational gaps foster reductionist diagnostic paradigms, which are amplified by health-system silos and defensive clinical practices, increasing the likelihood of non-indicated, irreversible interventions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The Five-Domain Framework offers a systemic model for understanding diagnostic breakdown in TMD management, providing a structured foundation for educational reform, integrated care pathways, and future empirical research.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16605,"journal":{"name":"Journal of oral rehabilitation","volume":"53 11","pages":"2190-2197"},"PeriodicalIF":3.8,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/joor.70294","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148829455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ashley Lebel, Charlotte Guillouet, André Porporatti, Yves Boucher
{"title":"Association of Vitamin B6 and Homocysteine–ACTH Coupling With Depressive and Anxiety Symptoms in Burning Mouth Syndrome: An Exploratory Case–Control Study","authors":"Ashley Lebel, Charlotte Guillouet, André Porporatti, Yves Boucher","doi":"10.1111/joor.70253","DOIUrl":"10.1111/joor.70253","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Burning mouth syndrome (BMS) is a chronic, idiopathic and debilitating orofacial pain disorder, increasingly discussed within oral dysaesthesia and nociplastic pain frameworks, in which psychological distress and stress-related mechanisms are frequently implicated. Vitamin B6, homocysteine and adrenocorticotropic hormone (ACTH) reflect biologically interconnected micronutrient, one-carbon-metabolic and neuroendocrine pathways, but their relevance to BMS and particularly their interrelationships within patients remains unclear.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To compare plasma vitamin B6, homocysteine and ACTH concentrations between patients with BMS and controls, and to characterise the relationships among these biomarkers and with anxiety and depression within each group.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>In this exploratory case–control ancillary analysis of the OPIODYN study, plasma pyridoxal 5′-phosphate (PLP; vitamin B6), homocysteine and ACTH were measured in 21 patients with BMS and 17 controls, and anxiety and depression were assessed with the Hospital Anxiety and Depression Scale (HADS). Between-group comparisons used 2-sided Mann–Whitney <i>U</i> tests with Hodges–Lehmann median differences and 95% confidence intervals (CIs). Within-group Spearman correlations and between-group differences in correlation strength (Δρ, Monte Carlo permutation) were computed, with Benjamini–Hochberg control of the false discovery rate within pre-declared families.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>No statistically significant between-group differences were observed for PLP, homocysteine or ACTH concentrations. Median differences were +5.35 nmol/L (95% CI, −14.88 to 26.78; <i>p</i> = 0.567) for PLP, −0.13 μmol/L (95% CI, −1.81 to 1.49; <i>p</i> = 0.907) for homocysteine and −0.66 pmol/L (95% CI, −1.61 to 0.35; <i>p</i> = 0.186) for ACTH. Most participants in both groups had adequate PLP and within-range homocysteine and basal ACTH. Homocysteine and ACTH were strongly correlated in patients with BMS (ρ = 0.806; 95% CI 0.562–0.891) but not in controls (ρ = 0.204; 95% CI, −0.344 to 0.668), with a significant between-group difference in correlation strength (Δρ = 0.602; <i>p</i> = 0.018). Among patients with BMS, both HADS subscales showed positive correlations with homocysteine and ACTH (ρ = 0.61–0.64; all <i>q</i> = 0.010), whereas no corresponding correlation was significant in controls, and PLP was not correlated with HADS or with the other biomarkers in either group. No single ","PeriodicalId":16605,"journal":{"name":"Journal of oral rehabilitation","volume":"53 11","pages":"2053-2063"},"PeriodicalIF":3.8,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/joor.70253","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148404975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}