Journal of Ophthalmic & Vision Research最新文献

{"title":"Posterior Microphthalmos Pigmentary Retinopathy Syndrome.","authors":"Syed Saifuddin Adeel,&nbsp;Syed Mohideen Ka,&nbsp;Anuj Sharma,&nbsp;Vinit J Shah,&nbsp;Adheesh Shetty","doi":"10.18502/jovr.v18i2.13190","DOIUrl":"https://doi.org/10.18502/jovr.v18i2.13190","url":null,"abstract":"<p><strong>Purpose: </strong>To report a case of a rare disease entity Posterior Microphthalmos Pigmentary Retinopathy Syndrome (PMPRS) in a 47-year-old female with a brief review of literature.</p><p><strong>Case report: </strong>A 47-year-old woman presented with a history of defective vision with an associated difficulty in night vision. Clinical workup was done, which included a thorough ocular examination showing diffuse pigmentary mottling of fundus, ocular biometry showing short axial length with normal anterior segment dimensions, electroretinography showing extinguished response, optical coherence tomography showing foveoschisis, and ultrasonography showing thickened sclera-choroidal complex. Findings were consistent with those reported by other authors with PMPRS.</p><p><strong>Conclusion: </strong>Posterior microphthalmia with or without other ocular and systemic associations should be suspected in cases with high hyperopia. It is mandatory to carefully examine the patient at presentation and close follow-ups are needed to maintain visual function.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 2","pages":"240-244"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172798/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9822860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical Punctal Occlusion; Combined Lacrimal Canaliculi Cauterization and Punctal Suturing for Severe Dry Eye.","authors":"Kohei Kuroda,&nbsp;Hiroshi Toshida,&nbsp;Yoko Sorita,&nbsp;Kohei Ichikawa,&nbsp;Yusuke Matsuzaki,&nbsp;Toshihiko Ohta","doi":"10.18502/jovr.v18i2.13179","DOIUrl":"https://doi.org/10.18502/jovr.v18i2.13179","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the treatment outcome of surgical punctal occlusion with combined canaliculi ablation and punctal suturing in patients with severe dry eye.</p><p><strong>Methods: </strong>Eleven eyes of seven patients were diagnosed with severe dry eye with decreased lacrimal secretion and were refractory to treatment with various eye drops and/or had repeatedly experienced loss of punctal plugs, and continued to experience subjective symptoms received surgical punctal occlusion. In 20 puncta, lacrimal canaliculi ablation was performed along the entire length of the lacrimal canaliculus where a diathermy needle could be inserted. After resection of the annulus fibrosus in the peri-punctal area, tight cross-stitch suturing of the puncta was performed with 8-0 absorbent thread. Visual acuity, corneal staining score according to the area (A) and density (D) classification, and Schirmer tear test (STT); tear break up time (tBUT); and subjective symptoms assessed by the University of North Carolina (UNC) and Dry Eye Management Scale were compared before and one year after surgery.</p><p><strong>Results: </strong>Recanalization occurred in 1/20 puncta (5.0% at month 5) in 1/11 eyes. Student's <i>t</i>-test showed significant improvement at one year compared with preoperative values for LogMAR value (<i>P</i> = 0.019), corneal staining score A (<i>P</i> = 0.00003) and D (<i>P</i> = 0.0003), STT (<i>P</i> = 0.004), and subjective symptoms (<i>P</i> = 0.015). No change was shown in tBUT and no serious adverse event occurred.</p><p><strong>Conclusion: </strong>This improved, minimally invasive surgical procedure has a low recanalization rate and achieves both objective and subjective improvements at one year.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 2","pages":"143-149"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172797/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9822859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How Many Fenestrations Should I Make When Placing a Baerveldt Glaucoma Implant? A Laboratory Study.","authors":"Michael C Yang,&nbsp;Christopher D Yang,&nbsp;Ken Y Lin","doi":"10.18502/jovr.v18i2.13181","DOIUrl":"https://doi.org/10.18502/jovr.v18i2.13181","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigates the effect of one versus two fenestrations on both fluid egress and opening pressure from a non-valved glaucoma implant.</p><p><strong>Methods: </strong>In this laboratory study, we used an <i>in vitro</i> closed system comprised of ligated silicone tubing connected to a fluid reservoir and manometer to simulate the tubing found in a Baerveldt glaucoma drainage implant. Fenestrations were created using an 8-0 Vicryl TG140-8 suture needle. Main outcome measures included volume of fluid egress and fenestration opening pressures, which were measured via micropipette and increasing pressure until fluid egress was observed.</p><p><strong>Results: </strong>No significant difference was observed in fluid egress between tubing with one versus two fenestrations at pressures <math><mo>≤</mo></math>40 mmHg. At 50 mmHg, a statistically significant difference was observed in fluid egress between tubing with one versus two fenestrations (<i>P</i> <math><mo><</mo></math> 0.05). The first fenestration opened at 10.5 <math><mo>±</mo></math> 3.77 mmHg and the second fenestration opened at 28.83 <math><mo>±</mo></math> 5.09 mmHg (average <math><mo>±</mo></math> standard deviation).</p><p><strong>Conclusion: </strong>Our <i>in vitro</i> findings suggest there may exist a critical pressure <math><mo>></mo></math>40 mmHg at which the second fenestration starts to play a significant role in fluid drainage. There may be no difference in the amount of fluid egress and effect on intraocular pressure between one or two tube fenestrations when preoperative intraocular pressure is <math><mo>≤</mo></math>40 mmHg.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 2","pages":"157-163"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172796/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9523699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rapid Assessment of Avoidable Visual Impairment in Two Coastal Districts of Eastern India for Determining Effective Coverage: A Cross-Sectional Study.","authors":"Amit Bhardwaj,&nbsp;Praveen Vashist,&nbsp;Suraj Singh Senjam,&nbsp;Vivek Gupta,&nbsp;Noopur Gupta,&nbsp;Souvik Manna","doi":"10.18502/jovr.v18i2.13185","DOIUrl":"https://doi.org/10.18502/jovr.v18i2.13185","url":null,"abstract":"<p><strong>Purpose: </strong>To measure the prevalence and causes of visual impairment (VI) among the 40+ age population in two coastal districts of India and to determine the levels of effective cataract surgical coverage (eCSC) and effective refractive error coverage (eREC) in the study population.</p><p><strong>Methods: </strong>A cross-sectional study was done on 4200 people chosen using cluster sampling in two coastal districts of Odisha, an eastern state in India. A team consisting of trained optometrists and social workers conducted the ocular examination which included unaided, pinhole, and aided visual acuity assessments followed by examination of the anterior segment and lens.</p><p><strong>Results: </strong>Overall, 3745 (89.2%) participants were examined from 60 study clusters, 30 in each district. Among those examined, 1677 (44.8%) were men, 2554 (68.2%) were educated and number? (17.8%) used distance spectacles during the survey. The prevalence of VI adjusted for age and gender was 12.77% (95% CI 11.85-13.69%). Multiple logistic regression showed that older age (OR 3.1; 95% CI 2.0-4.7) and urban residence (OR 1.2; 95% CI 1.0-1.6) were associated with VI. Being educated (OR 0.4; 95% CI 0.3-0.6) and using glasses (OR 0.3; 95% CI 0.5-0.2) were found to provide protection; therefore, resulting in lower instances of VI. Cataract (62.7%) and uncorrected refractive errors (27.1%) were the two main causes of VI. The eCSC was 35.1%, the eREC for distance was 40.0%, and the eREC for near was 35.7%.</p><p><strong>Conclusion: </strong>VI remains a challenge in Odisha, as the prevalence is high and the surgical coverage is poor. Nearly 90% of VI is avoidable indicating that targeted interventions are required to address this problem.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 2","pages":"182-191"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172807/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9523703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"P100 Wave Latency and Amplitude in Visual Evoked Potential Records in Different Visual Quadrants of Normal Individuals.","authors":"Leila Mirzaee Saba,&nbsp;Hassan Hashemi,&nbsp;Ebrahim Jafarzadehpour,&nbsp;Ali Mirzajani,&nbsp;Abbasali Yekta,&nbsp;Abolfazl Jafarzadehpour,&nbsp;Arghavan Zarei,&nbsp;Payam Nabovati,&nbsp;Mehdi Khabazkhoob","doi":"10.18502/jovr.v18i2.13184","DOIUrl":"https://doi.org/10.18502/jovr.v18i2.13184","url":null,"abstract":"<p><strong>Purpose: </strong>Assessment of the pattern visual evoked potential (PVEP) responses in different areas of visual fields in individuals with normal vision.</p><p><strong>Methods: </strong>This study was conducted on 80 eyes of normal subjects aged 18-35 years. All participants underwent refraction and visual acuity examination. Visual evoked potential (VEP) responses were recorded in different areas of field. The repeated measure test was used to compare the P100 latency and amplitude of PVEP among different areas.</p><p><strong>Results: </strong>The repeated measures analysis of variance showed a statistically significant difference among different areas in terms of amplitude and latency of P100 (<i>P</i> = 0.002 and <i>P</i> <math><mo><</mo></math> 0.001, respectively). According to the results, the highest and lowest amplitude of P100 was observed in inferior-nasal and superior areas, respectively. The highest and lowest latency of P100 was related to the temporal and inferior-nasal areas, respectively.</p><p><strong>Conclusion: </strong>This study partially revealed the details of local PVEP distribution in the visual field and there was a significant difference in the amplitude and latency of PVEP wave in different areas of the visual field.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 2","pages":"175-181"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172794/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9523700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Renal Function following Fluorescein Angiography in Diabetic Patients with Chronic Kidney Disease.","authors":"Nazanin Ebrahimiadib,&nbsp;Shaghayegh Hadavand Mirzaei,&nbsp;Hamid Riazi-Esfahani,&nbsp;Manouchehr Amini","doi":"10.18502/jovr.v18i2.13183","DOIUrl":"https://doi.org/10.18502/jovr.v18i2.13183","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effect of fluorescein dye usage on renal function in patients with diabetic retinopathy (DR) and chronic kidney disease (CKD).</p><p><strong>Methods: </strong>Diabetic patients with retinopathy who were candidate for fundus fluorescein angiography (FA) were evaluated for serum creatinine and urea levels within five days prior to performing the FA. Serum creatinine levels of 1.5 mg/dl or more in males and 1.4 mg/dl or more in females were both identified as CKD and were included in the study. An increase of 0.5 mg/dl or 25% in creatinine after FA was considered as contrast-induced acute kidney injury (AKI). Estimated glomerular filtration rate (eGFR) was also calculated for all patients using a CKD-Epi formula. CKD grading was determined based on eGFR values.</p><p><strong>Results: </strong>Forty-two patients agreed to participate, of which 23 (54.8%) were male. Seventeen patients were identified with grade 3a or lower CKD, 12 with grade 3b, 11 with grade 4, and two with grade 5 CKD. Considering all grades of CKD, the mean blood urea before and after angiography was 58.48 <math><mo>±</mo></math> 26.7 and 57 <math><mo>±</mo></math> 27.81 mg/dl, respectively (<i>P</i> = 0.475). The mean serum creatinine before and after the test was 1.89 <math><mo>±</mo></math> 1.04 and 1.87<math><mo>±</mo></math>0.99 mg/dl, respectively (<i>P</i> = 0.993). The mean eGFR before and after the test was 44.024 <math><mo>±</mo></math> 23.5447 and 43.850 <math><mo>±</mo></math> 21.8581 mL/min/1.73 m² <i>(P = 0.</i>875).</p><p><strong>Conclusion: </strong>According to the findings of this study, FA does not seem to further deteriorate kidney function in patients with diabetic associated CKD.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 2","pages":"170-174"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9523701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ziv-aflibercept in Diabetic Macular Edema: Relation of Subfoveal Choroidal Thickness with Visual and Anatomical Outcomes.","authors":"Siamak Moradian,&nbsp;Masoud Soheilian,&nbsp;Mahsan Asadi,&nbsp;Abdolreza Baghi,&nbsp;Hamid Safi,&nbsp;Seyed-Hossein Abtahi","doi":"10.18502/jovr.v18i2.13182","DOIUrl":"https://doi.org/10.18502/jovr.v18i2.13182","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effects of intravitreal ziv-aflibercept injections (IVZ) on subfoveal choroidal thickness (SCT) as well as on central macular thickness (CMT) and on best corrected visual acuity (BCVA) changes in eyes with center-involved diabetic macular edema (CI-DME).</p><p><strong>Methods: </strong>Fifty-seven eyes of 36 patients with CI-DME were included in this prospective interventional case series. Structural optical coherence tomography (OCT) and enhanced depth imaging OCT were performed at baseline followed by three monthly 1.25 mg IVZ injections. Changes of SCT, CMT, and BCVA at each follow-up session were assessed. The association between baseline SCT and its monthly changes with final visual and anatomical outcomes were also assessed.</p><p><strong>Results: </strong>CMT at baseline, and at the first, second, and third month follow-up sessions were 396 <math><mo>±</mo></math> 119, 344 <math><mo>±</mo></math> 115, 305 <math><mo>±</mo></math> 89, and 296 <math><mo>±</mo></math> 101 μm, respectively (<i>P</i>-value <math><mo><</mo></math> 0.001). SCT at baseline, and at months one, two, and three were 236 <math><mo>±</mo></math> 47, 245 <math><mo>±</mo></math> 56, 254 <math><mo>±</mo></math> 54, and 241 <math><mo>±</mo></math> 54 μm, respectively (<i>P</i>-value <math><mo>></mo></math> 0.99). Corresponding figures for BCVA were 0.58 <math><mo>±</mo></math> 0.29, 0.47 <math><mo>±</mo></math> 0.31, 0.4 <math><mo>±</mo></math> 0.24, and 0.37 <math><mo>±</mo></math> 0.23 LogMAR, respectively (<i>P</i>-value <math><mo><</mo></math> 0.001). There was a statistically significant positive correlation between BCVA and CMT changes following IVZ injections (<i>P</i>-value <math><mo><</mo></math> 0.001). However, there were no significant correlations between SCT changes and visual acuity (VA) and CMT changes following IVZ injections.</p><p><strong>Conclusion: </strong>IVZ improved visual outcomes and macular thickness profiles in patients with CI-DME. However, IVZ had no significant effect on SCT. Baseline SCT and its monthly changes had no association with visual and anatomical outcomes.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 2","pages":"164-169"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172803/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9822862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Congenital Retinal Macrovessel; Optical Coherence Tomography Angiography Features.","authors":"Ramin Nourinia,&nbsp;Kiana Hassanpour","doi":"10.18502/jovr.v18i2.13191","DOIUrl":"https://doi.org/10.18502/jovr.v18i2.13191","url":null,"abstract":"This is a Photo Essay and does not have an abstract. Please download the PDF or view the article in HTML.","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 2","pages":"245-248"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172802/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9822858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Survey on Orbital Space-Occupying Lesions during a Twelve-Year Period from a Referral Center in Iran.","authors":"Abbas Bagheri,&nbsp;Parisa Ashtar-Nakhaie,&nbsp;Maryam Aletaha,&nbsp;Bahareh Kheiri,&nbsp;Amirreza Veisi","doi":"10.18502/jovr.v18i2.13187","DOIUrl":"https://doi.org/10.18502/jovr.v18i2.13187","url":null,"abstract":"<p><strong>Purpose: </strong>In this study, we describe different orbital space-occupying lesions (SOLs) from a referral center in Iran.</p><p><strong>Methods: </strong>In this retrospective case series, all records of \"orbital tumors\" with a definite histopathologic diagnosis at a referral center in Iran were reviewed from April 2008 to May 2020.</p><p><strong>Results: </strong>A total of 375 orbital SOLs were included. The study population consisted of 212 (56.5%) female and 163 (43.5%) male subjects with overall mean age of 31.09 <math><mo>±</mo></math> 21.80 years. The most common clinical presentation was proptosis and the superotemporal quadrant was the most frequent site of involvement. Extraconal lesions (276 cases, 73.6%) outnumbered intraconal lesions (99 cases 26.4%). The great majority of SOLs (344, 91.7%) were primary, while 24 (6.4%) were secondary and 7 (1.9%) were metastatic. Benign lesions (309, 82.4%) were much more common than malignant SOLs (66, 17.6%). Overall, dermoid cysts and malignant lymphoma were the most prevalent benign and malignant orbital SOLs, respectively. The malignant to benign lesion ratio was 0.46 in children (<math><mo>≤</mo></math>18 years), 0.81 in middle-aged subjects (19-59 years), and 5.9 in older (<math><mo>≥</mo></math>60 years) cases. The most common type of malignancy was rhabdomyosarcoma in children, lymphoma in middle-aged subjects, and invasive basal cell carcinoma in older age group.</p><p><strong>Conclusion: </strong>Over the 12-year study period, benign, primary, extraconal orbital SOLs were more frequent than malignant, secondary, and intraconal lesions. The ratio of malignant lesions increased with age in this cohort of patients.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 2","pages":"202-211"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172800/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9523702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Applications of Artificial Intelligence in Glaucoma.","authors":"Siamak Yousefi","doi":"10.18502/jovr.v18i1.12730","DOIUrl":"10.18502/jovr.v18i1.12730","url":null,"abstract":"<p><p>Ophthalmology is one of the major imaging-intensive fields of medicine and thus has potential for extensive applications of artificial intelligence (AI) to advance diagnosis, drug efficacy, and other treatment-related aspects of ocular disease. AI has made impressive progress in ophthalmology within the past few years and two autonomous AI-enabled systems have received US regulatory approvals for autonomously screening for mid-level or advanced diabetic retinopathy and macular edema. While no autonomous AI-enabled system for glaucoma screening has yet received US regulatory approval, numerous assistive AI-enabled software tools are already employed in commercialized instruments for quantifying retinal images and visual fields to augment glaucoma research and clinical practice. In this literature review (non-systematic), we provide an overview of AI applications in glaucoma, and highlight some limitations and considerations for AI integration and adoption into clinical practice.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 1","pages":"97-112"},"PeriodicalIF":2.0,"publicationDate":"2023-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020779/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9146895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}