Journal of Ophthalmic & Vision Research最新文献

{"title":"Eye Care Utilization among Older Subjects with Visual Impairment in Northwest Ethiopia.","authors":"Aragaw Kegne Assaye,&nbsp;Melkamu Temeselew Tegegn,&nbsp;Gizachew Tilahun Belete","doi":"10.18502/jovr.v18i3.13779","DOIUrl":"https://doi.org/10.18502/jovr.v18i3.13779","url":null,"abstract":"<p><strong>Purpose: </strong>To find out the level of eye care service utilization and its determinants among the elderly visually impaired populations while visiting ophthalmic outreach locations in North-Western Ethiopia, 2021.</p><p><strong>Methods: </strong>An ophthalmic outreach-based cross-sectional study was conducted on 852 visually impaired older people. Participants were selected by using a systematic random sampling method from January to July 2021. Data were collected by using an interviewer-administered questionnaire and an ocular examination. The collected data were entered into the Epi Info 7, and analyzed using SPSS 20. A binary logistic regression was fitted.</p><p><strong>Results: </strong>A total of 821 participants, with a response rate of 96.5%, were included in the study. The utilization of eye care services within the past two years prior to the study was 21.1% (95 % CI: 18.2-23.9). Having systemic disease (AOR = 3.2, 95% CI: 1.5-7.0), being a spectacle wearer (AOR = 4.5, 95% CI: 2.0-9.4), having visual impairment at distance (AOR = 2.9; 95% CI: 1.5-5.6), being blind (AOR = 2.9; 95% CI: 1.5-5.6), duration of visual impairment <math><mo>≤</mo></math>1 year (AOR = 2.5; 95% CI: 1.3-4.9) were all significantly associated.</p><p><strong>Conclusion: </strong>In this study, utilization of eye care services was low. Being visually impaired at distance, being blind, recent onset of visual impairment, being a spectacle wearer, and having systemic disease were all related to the use of eye care services. The commonest barriers to utilization of eye care services were financial scarcity and long distances between eye care facilities.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 3","pages":"306-317"},"PeriodicalIF":2.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432933/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10106037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stem Cell Therapy in Stargardt Disease: A Systematic Review.","authors":"Atousa Moghadam Fard,&nbsp;Reza Mirshahi,&nbsp;Masood Naseripour,&nbsp;Khalil Ghasemi Falavarjani","doi":"10.18502/jovr.v18i3.13780","DOIUrl":"https://doi.org/10.18502/jovr.v18i3.13780","url":null,"abstract":"<p><p>This article aimed to review current literature on the safety and efficacy of stem cell therapy in Stargardt disease. A comprehensive literature search was performed, and two animal and eleven human clinical trials were retrieved. These studies utilized different kinds of stem cells, including human or mouse embryonic stem cells, mesenchymal stem cells, bone marrow mononuclear fraction, and autologous bone marrow-derived stem cells. In addition, different injection techniques including subretinal, intravitreal, and suprachoroidal space injections have been evaluated. Although stem cell therapy holds promise in improving visual function in patients with Stargardt disease, further investigation is needed to determine the long-term benefits, safety, and efficacy in determining the best delivery method and selecting the most appropriate stem cell type.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 3","pages":"318-327"},"PeriodicalIF":2.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10106039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and Autofluorescence Findings in Eyes with Pinguecula and Pterygium.","authors":"Amir-Hooshang Beheshtnejad,&nbsp;Hamed Ghassemi,&nbsp;Hossein Abdolkhalegh,&nbsp;Mehrnaz Atighehchian","doi":"10.18502/jovr.v18i3.13773","DOIUrl":"https://doi.org/10.18502/jovr.v18i3.13773","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the autofluorescence size and properties of pterygium and pinguecula by anterior segment autofluorescence (AS-AF) imaging and demonstrate the difference of autofluorescence size presented in AS-AF imaging compared to the extend size of the conjunctival lesion measured by anterior segment slit-lamp photography (AS-SLE).</p><p><strong>Methods: </strong>Twenty-five patients with primary pterygium and twenty-five with pinguecula were included in the study. In addition, 25 normal subjects were also enrolled as the control group. The AS-AF characteristics of pterygium and pinguecula lesions were analyzed. The size of lesions displayed in the AS-SLE photography versus the AS-AF images were also compared. AS-AF images were obtained using a Heidelberg retina angiograph which focused on the anterior segment. AS-SLE photography was acquired using a digital imaging system (BX900 HAAG-STREIT).</p><p><strong>Results: </strong>There were 44 (58.7%) male and 31 (41.3%) female patients; 19 (76%) and 20 (80%) patients had bilateral pterygium and pinguecula, respectively. All pinguecula lesions reflected hyperautofluorescence pattern in the AS-AF imaging. In 24 (96%) patients, the hyperautofluoresecence pattern was larger than the size of the clinical lesions displayed with the AS-SLE photography. Twenty-one (84%) patients with pterygium reflected a hyperautofluorescence pattern in AS-AF images; in one (4%) patient, the hyperautofluorescence pattern was larger than the clinical lesion size and four (16%) patients had no autofluorescence patterns in the AS-AF images. In the control group, in 14 (56%) subjects, a hypoautofluorescent pattern was revealed in the conjunctiva in AS-AF images. However, in 11 (44%) patients, hyperautofluorescence patterns were detected.</p><p><strong>Conclusion: </strong>AS-AF is a useful modality to monitor vascularization in conjunctival lesions. Pingueculae and pterygium show hyperautofluorescence in AS-AF imaging. The real size of the pinguecula lesions may be estimated with AS-AF characteristics, mostly presenting larger than the area size in AS-SLE photography. The autofluorescence size of the pterygium is smaller than the extent of visible pterygium in slit-lamp photography.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 3","pages":"260-266"},"PeriodicalIF":2.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432937/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10106041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intravitreal Injections and Face Masks: Endophthalmitis Risk Before and During the COVID-19 Pandemic.","authors":"Saeed Karimi,&nbsp;Homayoun Nikkhah,&nbsp;Amir Mohammadzadeh,&nbsp;Alireza Ramezani,&nbsp;Iman Ansari,&nbsp;Hosein Nouri,&nbsp;Seyed-Hossein Abtahi","doi":"10.18502/jovr.v18i3.13776","DOIUrl":"https://doi.org/10.18502/jovr.v18i3.13776","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the added risk of acute endophthalmitis after intravitreal injections associated with the widespread use of face masks during the COVID-19 pandemic.</p><p><strong>Methods: </strong>In this retrospective, single-center study, records of patients with acute endophthalmitis following intravitreal bevacizumab (IVB) injections during the pre-COVID era-that is, March 1<math><msup><mrow></mrow><mtext>st</mtext></msup></math>, 2013 to October 31<math><msup><mrow></mrow><mtext>st</mtext></msup></math>, 2019 -and the COVID-19 era-that is, March 1<math><msup><mrow></mrow><mtext>st</mtext></msup></math>, 2020 to April 1<math><msup><mrow></mrow><mtext>st</mtext></msup></math>, 2021 -were reviewed and compared.</p><p><strong>Results: </strong>A total of 28,085 IVB injections were performed during the pre-COVID era; nine eyes of nine patients developed acute post-IVB endophthalmitis in this era, giving an overall incidence of 0.032% (3.2 in 10,000 injections). In the COVID era, 10,717 IVB injections were performed; four eyes of four patients developed acute post-IVB endophthalmitis in this era, giving an overall incidence of 0.037% (3.7 in 10,000 injections). The incidences of post-IVB endophthalmitis during these two eras were not statistically significantly different (<i>P</i> = 0.779).</p><p><strong>Conclusion: </strong>Face masking protocols seem unlikely to impose any additional risk of post-IVB endophthalmitis.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 3","pages":"283-288"},"PeriodicalIF":2.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432929/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10046631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Krill's Disease: A Newer Management Option.","authors":"Sarang P Lambat,&nbsp;Vinay B Nangia,&nbsp;Prabhat V Nangia,&nbsp;Neha H Shah,&nbsp;Swati D Mishra","doi":"10.18502/jovr.v18i3.13782","DOIUrl":"https://doi.org/10.18502/jovr.v18i3.13782","url":null,"abstract":"<p><strong>Purpose: </strong>To report a case of a young female who presented with scotoma in the right eye for few days.</p><p><strong>Case report: </strong>Krill's disease or acute retinal pigment epithelitis (ARPE) is a self-limiting retinal disease with no specific treatment. Typical clinical and imaging features helped us to diagnose her with ARPE. Intravenous methylprednisolone (IVMP), which gives a rapid anti-inflammatory response, was advised. An SD-OCT scan post-injection showed a reduction in hyperreflectivity and height of lesion at day 3 and near total resolution by day 5.</p><p><strong>Conclusion: </strong>This case suggests rapid resolution of ARPE with the use of IVMP.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 3","pages":"334-338"},"PeriodicalIF":2.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10106038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Characteristics and Outcomes of Endophthalmitis Before and During the COVID-19 Pandemic.","authors":"Blake H Fortes,&nbsp;Prashant D Tailor,&nbsp;Timothy T Xu,&nbsp;Robert A Churchill,&nbsp;Matthew R Starr","doi":"10.18502/jovr.v18i3.13777","DOIUrl":"https://doi.org/10.18502/jovr.v18i3.13777","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the clinical characteristics and visual acuity outcomes of patients who presented with endophthalmitis prior to and during the coronavirus disease 2019 (COVID-19) pandemic.</p><p><strong>Methods: </strong>This multicenter retrospective case series with historical controls included consecutive patients presenting with any form of endophthalmitis from March 1, 2019 to September 1, 2019 (pre-COVID-19) and from March 1, 2020 to September 1, 2020 (COVID-19) at Mayo Clinic Rochester (MCR), Health System (MCHS), Arizona (MCA), and Florida (MCF) sites. Cases were divided into \"pre-COVID-19\" versus \"COVID-19\" groups depending on when they first presented with endophthalmitis.</p><p><strong>Results: </strong>Twenty-eight cases of endophthalmitis presented to all Mayo Clinic sites during the study period. Of these, 10 patients presented during the first six months of the COVID-19 pandemic. During the same six-month period the year prior, 18 patients presented with endophthalmitis. Endophthalmitis etiology (post-injection, post-cataract extraction, post-glaucoma filtering surgery, post-pars plana vitrectomy, endogenous, and others) was similar between both groups (<i>P</i> = 0.34), as was post-injection endophthalmitis rate (<i>P</i> = 0.69), days to presentation (<i>P</i> = 0.07), initial management (<i>P</i> = 0.11), culture-positivity rate (<i>P</i> = 0.70), and need for subsequent pars plana vitrectomy (<i>P</i> = 1). Visual acuity outcomes were similar between both groups at six months, however, the mean LogMAR visual acuity at presentation was worse in the COVID-19 group compared to the pre-COVID-19 group (2.44 vs 1.82; <i>P</i> = 0.026).</p><p><strong>Conclusion: </strong>Clinical characteristics and the post-injection endophthalmitis rate were similar during both periods, however, patients presented with worse vision during the pandemic suggesting that the pandemic may have contributed to delayed presentation, regardless, outcomes are still poor.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 3","pages":"289-296"},"PeriodicalIF":2.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432927/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10106042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diffuse Pigment Release in a Patient Undergoing Tumor-Infiltrating Lymphocyte Immunotherapy for Acral Malignant Melanoma.","authors":"Madison Kerley,&nbsp;Niloofar Piri,&nbsp;Aparna Ramasubramanian","doi":"10.18502/jovr.v18i3.13783","DOIUrl":"https://doi.org/10.18502/jovr.v18i3.13783","url":null,"abstract":"This is a Photo Essay and does not have an abstract. Please download the PDF or view the article in HTML.","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 3","pages":"339-341"},"PeriodicalIF":2.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10106040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bilateral Giant Full Thickness Macular Holes: An Infrequent Manifestation of Alport Syndrome.","authors":"Saeed Karimi,&nbsp;Niloofar Mohammad Bagheri Rafsanjani","doi":"10.18502/jovr.v18i3.13781","DOIUrl":"https://doi.org/10.18502/jovr.v18i3.13781","url":null,"abstract":"<p><strong>Purpose: </strong>To report a case of Alport syndrome presenting with bilateral giant full-thickness macular holes, hypertensive chorioretinopathy, and exudative retinal detachment.</p><p><strong>Case report: </strong>A 20 year-old man, a known case of Alport syndrome on hemodialysis, was referred to our clinic with bilateral vision loss initiated about 10 years prior to presentation, which exacerbated in the month prior to our visit. Bilateral large full-thickness macular holes, hypertensive chorioretinopathy, and exudative retinal detachment were detected in fundus examination. The patient had previous genetic counseling confirming the diagnosis of Alport syndrome. During follow-up, macular holes were covered with a thick epiretinal membrane and visual acuity decreased progressively in two weeks. Pars plana vitrectomy was performed in the right eye. Two weeks following surgery, the macular hole was closed and visual acuity improved significantly.</p><p><strong>Conclusion: </strong>Bilateral giant full-thickness macular holes are uncommon presentations of Alport syndrome. The retinal findings may be caused by an inefficient type IV collagen presenting in the Bruch's membrane and in the internal limiting membrane. Pars plana vitrectomy can be considered to repair macular holes in these patients.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 3","pages":"328-333"},"PeriodicalIF":2.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432934/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10405639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does Head Tilt Influence Facial Appearance More Than Head Turn?","authors":"Mohamad Reza Akbari,&nbsp;Masoud Khorrami-Nejad,&nbsp;Haleh Kangari,&nbsp;Mohsen Heirani,&nbsp;Alireza Akbarzadeh Baghban,&nbsp;Kiana Raeesdana,&nbsp;Babak Masoomian","doi":"10.18502/jovr.v18i3.13778","DOIUrl":"https://doi.org/10.18502/jovr.v18i3.13778","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the frequency of facial asymmetry parameters in patients with head tilt versus those with head turn.</p><p><strong>Methods: </strong>This cross-sectional comparative study was performed on 155 cases, including 58 patients with congenital pure head turn due to Duane retraction syndrome (DRS), 33 patients with congenital pure head tilt due to upshoot in adduction or DRS, and 64 orthotropic subjects as the control group. The facial appearance was evaluated by computerized analysis of digital photographs of patients' faces. Relative facial size (the ratio of the distance between the external canthus and the corner of the lips of both face sides) and facial angle (the angular difference between a line that connects two external canthi and another line that connects the two corners of the lips) measured as quantitative facial parameters. Qualitative parameters were evaluated by the presence of one-sided face, cheek, and nostril compression; and columella deviation.</p><p><strong>Results: </strong>The facial asymmetry frequency in patients with head tilt, head turn, and orthotropic subjects was observed in 32 (97%), 50 (86.2%), and 22 (34.3%), respectively (<i>P</i> <math><mo><</mo></math> 0.001). In patients with head tilt and head turn, the mean facial angle was 1.78º <math><mo>±</mo></math> 1.01º and 1.19º <math><mo>±</mo></math> 0.84º, respectively (<i>P</i> = 0.004) and the mean relative facial size was 1.027 <math><mo>±</mo></math> 0.018 and 1.018 <math><mo>±</mo></math> 0.014, respectively (<i>P</i> = 0.018). The frequencies of one-sided nostril compression, cheek compression, face compression, and columella deviation in patients with pure head tilt were found in 19 (58%), 21 (64%), 19 (58%), and 19 (58%) patients, respectively, and in patients with pure head turn the frequencies were observed in 42 (72%), 37 (63%), 27 (47%), and 43 (74%), respectively. All quantitative and qualitative facial asymmetry parameters and facial asymmetry frequencies were significantly higher in head tilt and head turn patients as compared to the control group (<i>P</i> <math><mo><</mo></math> 0.001).</p><p><strong>Conclusion: </strong>All facial asymmetry parameters in patients with head tilt and head turn were significantly higher than orthotropic subjects. The quantitative parameters such as relative facial size and facial angle were significantly higher in patients with pure head tilt than pure head turn. The results revealed that pure head tilt was associated with a higher prevalence of facial asymmetry than pure head turn.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 3","pages":"297-305"},"PeriodicalIF":2.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432935/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10050023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgically Managed Orbital Tumors: A Case Series from a Referral Center in Iran.","authors":"Arman Mashayekhi","doi":"10.18502/jovr.v18i2.13178","DOIUrl":"10.18502/jovr.v18i2.13178","url":null,"abstract":"","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 2","pages":"141-142"},"PeriodicalIF":1.6,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172801/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9839598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}