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Diagnostic Reference Levels in PET Imaging at Chulabhorn Hospital, Thailand. 泰国 Chulabhorn 医院 PET 成像诊断参考水平。
IF 1
Journal of nuclear medicine technology Pub Date : 2024-09-05 DOI: 10.2967/jnmt.124.267576
Phornpailin Pairodsantikul, Paramest Wongsa, Chaluntorn Wongkri, Paphawarin Burasothikul, Attapon Jantarato, Chanisa Chotipanich
{"title":"Diagnostic Reference Levels in PET Imaging at Chulabhorn Hospital, Thailand.","authors":"Phornpailin Pairodsantikul, Paramest Wongsa, Chaluntorn Wongkri, Paphawarin Burasothikul, Attapon Jantarato, Chanisa Chotipanich","doi":"10.2967/jnmt.124.267576","DOIUrl":"10.2967/jnmt.124.267576","url":null,"abstract":"<p><p>Diagnostic reference levels (DRLs) are an important tool for controlling radiation exposure and ensuring safety in medical applications. In Thailand, DRL data have been gathered and established for nuclear medicine diagnostics since 2021. However, there is a lack of information on PET imaging examinations. At the National Cyclotron and PET Scan Centre, Chulabhorn Hospital, radiopharmaceuticals are produced for medical imaging and research, and a wide range of PET/CT and PET/MRI examinations are performed. Our objective was to investigate the administered activity of radiopharmaceuticals in patients undergoing PET imaging, especially the existing data on DRLs in medical diagnostic imaging. <b>Methods:</b> This was a retrospective study on nuclear medicine patients at the National Cyclotron and PET Scan Centre in 2023. Statistical analysis, including the mean and the 75th percentile values, was conducted to determine DRLs according to the International Commission on Radiological Protection guidelines. <b>Results:</b> The center performed 8,711 PET/CT and PET/MRI studies with 13 protocols in 2023. The most commonly administered activity was <sup>18</sup>F-FDG in oncology and neurology examinations, with DRLs of 186.11 and 136.16 MBq, respectively. These values were notably almost twice lower than several reports in other countries. <b>Conclusion:</b> There is a lack of comprehensive data on most DRLs for PET imaging at this center because of the nonwidespread use of several radiopharmaceuticals. However, the lower DRLs for <sup>18</sup>F-FDG can highlight the need for ongoing investigation toward the establishment of local DRLs, as well as assurance on the safety and efficiency of radiation used in nuclear medicine.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141432146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brain Death Scintigraphy: Do Not Blow the Flow. 脑死亡闪烁成像：别吹牛。
IF 1
Journal of nuclear medicine technology Pub Date : 2024-09-05 DOI: 10.2967/jnmt.124.267894
Julie D Bolin
{"title":"Brain Death Scintigraphy: Do Not Blow the Flow.","authors":"Julie D Bolin","doi":"10.2967/jnmt.124.267894","DOIUrl":"10.2967/jnmt.124.267894","url":null,"abstract":"<p><p>Brain death denotes the loss of function in both the cerebrum and the brain stem, leading to coma, absence of spontaneous respiration in the setting of adequate stimulus, and the cessation of all brain stem reflexes. Although spinal reflexes such as deep tendon, plantar flexion, and withdrawal reflexes may persist, recovery is not possible. The cessation of brain function qualifies as death because of its central role in coordinating vital bodily functions. Although brain death is largely determined by a clinical and neurologic examination, confounding variables may necessitate ancillary testing such as cerebral brain perfusion imaging.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Renal Cortical Imaging. 肾皮质成像
IF 1
Journal of nuclear medicine technology Pub Date : 2024-09-05 DOI: 10.2967/jnmt.124.268301
Mary Beth Farrell
{"title":"Renal Cortical Imaging.","authors":"Mary Beth Farrell","doi":"10.2967/jnmt.124.268301","DOIUrl":"10.2967/jnmt.124.268301","url":null,"abstract":"","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Review of the Clinical and Technical Aspects of 99mTc-Dimercaptosuccinic Acid Renal Imaging: The Comeback "Kit". 99m锝-二巯基丁二酸肾脏成像的临床和技术回顾：卷土重来的 "工具包
IF 1
Journal of nuclear medicine technology Pub Date : 2024-09-05 DOI: 10.2967/jnmt.123.267185
Ruth Lim, Neha Kwatra, Valentina Ferrer Valencia, Katelyn N Collins, Reza Vali, Frederic H Fahey, S Ted Treves
{"title":"Review of the Clinical and Technical Aspects of <sup>99m</sup>Tc-Dimercaptosuccinic Acid Renal Imaging: The Comeback \"Kit\".","authors":"Ruth Lim, Neha Kwatra, Valentina Ferrer Valencia, Katelyn N Collins, Reza Vali, Frederic H Fahey, S Ted Treves","doi":"10.2967/jnmt.123.267185","DOIUrl":"10.2967/jnmt.123.267185","url":null,"abstract":"<p><p><sup>99m</sup>Tc-labeled dimercaptosuccinic acid (<sup>99m</sup>Tc-DMSA) imaging is a well-established and highly sensitive method for the diagnosis of several renal cortical disorders affecting children and adults. Beginning in 2014, <sup>99m</sup>Tc-DMSA availability was severely impaired when it was added to the Drug Shortages List of the U.S. Food and Drug Administration and was commercially unavailable thereafter. The agent shortage negatively impacted practitioners' ability to evaluate renal cortical defects in children and adults and changed renal imaging practice. A survey among pediatric nuclear medicine clinicians confirmed the clinical need for <sup>99m</sup>Tc-DMSA. Finally, in early 2023 the Food and Drug Administration again approved <sup>99m</sup>Tc-DMSA in the United States. During the <sup>99m</sup>Tc-DMSA shortage, established practitioners may not have had the opportunity of using <sup>99m</sup>Tc-DMSA as they were accustomed in their experience. Also, newer imaging specialists and referring physicians and technologists may not have benefited from having <sup>99m</sup>Tc-DMSA in their training. Therefore, it is time to bring back <sup>99m</sup>Tc-DMSA into the armamentarium of imaging methods available to evaluate regional cortical renal function.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Developing Communication Support Material for Sharing Information with Patients Undergoing an 18F-FDG PET/CT Examination. 开发与接受 18F-FDG PET/CT 检查的患者共享信息的交流辅助材料。
IF 1
Journal of nuclear medicine technology Pub Date : 2024-09-05 DOI: 10.2967/jnmt.124.267672
Camilla Andersson, Berit Möller-Christensen
{"title":"Developing Communication Support Material for Sharing Information with Patients Undergoing an <sup>18</sup>F-FDG PET/CT Examination.","authors":"Camilla Andersson, Berit Möller-Christensen","doi":"10.2967/jnmt.124.267672","DOIUrl":"10.2967/jnmt.124.267672","url":null,"abstract":"<p><p>Our aim was to develop communication support material for information sharing related to an <sup>18</sup>F-FDG PET/CT examination. <b>Methods:</b> The study had a qualitative design adapting a multiphase structure. A prototype of communication support material consisting of illustrations and text related to an <sup>18</sup>F-FDG PET/CT examination was developed. Interviews were conducted with patients scheduled for an <sup>18</sup>F-FDG PET/CT examination for the first time, and questionnaires were collected from health care professionals with experience in <sup>18</sup>F-FDG PET/CT. The communication support material was revised until consensus was reached about it. <b>Results:</b> The results are based on interviews with patients (<i>n</i> = 10) and questionnaires collected from health care professionals (<i>n</i> = 9). The overall theme revealed that patient information about an <sup>18</sup>F-FDG PET/CT examination is a balancing act between text and illustrations. The analysis showed 2 categories: \"illustrations as a complement\" and \"easy-to-understand layout.\" <b>Conclusion:</b> The participants strengthened the development of the communication support material by bringing in valuable viewpoints from various perspectives. The results support a person-centered approach in which information about an <sup>18</sup>F-FDG PET/CT examination can be adapted to each patient's needs as a balancing act between text and illustrations.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Single Hepatic Metastasis of Cranial Meningioma on [18F]FDG PET/CT 16 Years After Initial Surgery. 首次手术 16 年后，颅脑脑膜瘤的[18F]FDG PET/CT 显示出现单个肝转移。
IF 1
Journal of nuclear medicine technology Pub Date : 2024-08-13 DOI: 10.2967/jnmt.124.267905
Yan Cui, Xin Zhou, Nan Li
{"title":"A Single Hepatic Metastasis of Cranial Meningioma on [<sup>18</sup>F]FDG PET/CT 16 Years After Initial Surgery.","authors":"Yan Cui, Xin Zhou, Nan Li","doi":"10.2967/jnmt.124.267905","DOIUrl":"https://doi.org/10.2967/jnmt.124.267905","url":null,"abstract":"<p><p>Hepatic metastases of cranial meningiomas are rare, particularly when they present as a delayed, solitary metastasis, which poses a challenge for imaging-based diagnosis. [<sup>18</sup>F]FDG PET/CT facilitates diagnosis and posttreatment restaging, whereas somatostatin receptor-targeted PET demonstrates high sensitivity and specificity in the diagnosis of meningiomas and may potentially evaluate the viability of theranostics approaches, particularly for treatment-resistant meningiomas.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adrenal Oncocytoma: A Rare Tumor with Conflicting Imaging Features. 肾上腺肿瘤细胞瘤：影像特征相互矛盾的罕见肿瘤
IF 1
Journal of nuclear medicine technology Pub Date : 2024-08-13 DOI: 10.2967/jnmt.124.267465
Parneet Singh, Girish Kumar Parida, Tejasvini Singhal, Pavithra Ayyanar, Kishore Kumar Behera, Kanhaiyalal Agrawal, Pritinanda Mishra, P Sai Sradha Patro
{"title":"Adrenal Oncocytoma: A Rare Tumor with Conflicting Imaging Features.","authors":"Parneet Singh, Girish Kumar Parida, Tejasvini Singhal, Pavithra Ayyanar, Kishore Kumar Behera, Kanhaiyalal Agrawal, Pritinanda Mishra, P Sai Sradha Patro","doi":"10.2967/jnmt.124.267465","DOIUrl":"https://doi.org/10.2967/jnmt.124.267465","url":null,"abstract":"<p><p>Oncocytic adenomas are rare benign tumors that typically originate in organs such as the kidneys, thyroid, parathyroid, salivary glands, or pituitary gland. Oncocytic adenoma of the adrenal gland is extremely rare. It often shows heterogeneous, nonspecific features on anatomic imaging, as well as high <sup>18</sup>F-FDG avidity despite its benign nature. The definitive diagnosis relies on histopathologic examination, including immunohistochemistry. We present an incidentally detected benign adrenal oncocytic adenoma with intense <sup>18</sup>F-FDG uptake mimicking sinister pathologies.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combined Supine-Prone Myocardial Perfusion Imaging: Enhancing Diagnostic Accuracy. 联合仰卧位心肌灌注成像：提高诊断准确性。
IF 1
Journal of nuclear medicine technology Pub Date : 2024-08-13 DOI: 10.2967/jnmt.124.268017
Mary Beth Farrell
{"title":"Combined Supine-Prone Myocardial Perfusion Imaging: Enhancing Diagnostic Accuracy.","authors":"Mary Beth Farrell","doi":"10.2967/jnmt.124.268017","DOIUrl":"https://doi.org/10.2967/jnmt.124.268017","url":null,"abstract":"<p><p>The combined supine-prone imaging protocol for SPECT myocardial perfusion imaging offers significant advantages over supine imaging alone. By comparing supine and prone images, one can distinguish attenuation artifacts in the inferior and anterior walls from true perfusion defects, thus improving specificity and diagnostic accuracy. The recommended protocol is to perform prone imaging after supine stress imaging when perfusion defects are noted. The additional prone imaging time is 20%-40% less than the standard supine imaging time. Implementing prone imaging can optimize patient care and provide substantial benefits for nuclear cardiology labs, especially those without attenuation correction.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
51Cr Red Blood Cells in the Study of Hematologic Disease: A Historical Review. 51Cr 红细胞在血液病研究中的应用：历史回顾
IF 1
Journal of nuclear medicine technology Pub Date : 2024-08-13 DOI: 10.2967/jnmt.124.267702
George H Hinkle
{"title":"<sup>51</sup>Cr Red Blood Cells in the Study of Hematologic Disease: A Historical Review.","authors":"George H Hinkle","doi":"10.2967/jnmt.124.267702","DOIUrl":"https://doi.org/10.2967/jnmt.124.267702","url":null,"abstract":"<p><p>The early years of nuclear medicine included the development and clinical use of several in vitro or nonimaging procedures. The use of radionuclides as replacements for nonradioactive dyes brought improved accuracies and less subjective measurements to indicator dilution studies of body compartments such as the gastrointestinal system, lungs, urinary system, and vascular space. A popular nuclear medicine procedure was the radionuclide dilution method for quantitation of whole-blood volume or red blood cell volume or mass using <sup>51</sup>Cr-labeled red blood cells-an important diagnostic element in patients suspected of having polycythemia vera, congestive heart failure, hypertension, shock, syncope, and other abnormal blood volume disorders. The radionuclide dilution method led to improved evaluation of red blood cell survival, which is important for clinical treatment planning in anemia and confirmation of splenic sequestration of damaged red blood cells. Although it was discovered that <sup>51</sup>Cr was a chemically stable radiolabel of red blood cells after binding to intracellular hemoglobin, few nuclear medicine departments offered the clinical study for referring physicians because it required laboratory expertise for technologists, patient coordination, and a time-consuming procedure. The introduction of improved methods that are less time-consuming and have clinically acceptable results, along with the discontinuation of the sodium chromate <sup>51</sup>Cr injection radiopharmaceutical by manufacturers, has consigned <sup>51</sup>Cr red blood cells for red blood cell volume, mass, or survival evaluation to the list of retired nuclear medicine studies.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unexpected Artifact on 99mTc-Methylene Diphosphonate Bone Scintigraphy. 99m锝-亚甲基二膦酸盐骨闪烁成像的意外伪影。
IF 1
Journal of nuclear medicine technology Pub Date : 2024-07-17 DOI: 10.2967/jnmt.124.267795
Suliman G Salih, Abdelbagi O Osman, Ajnas M Alkatheeri, Mohamed B Hassaneen
{"title":"Unexpected Artifact on <sup>99m</sup>Tc-Methylene Diphosphonate Bone Scintigraphy.","authors":"Suliman G Salih, Abdelbagi O Osman, Ajnas M Alkatheeri, Mohamed B Hassaneen","doi":"10.2967/jnmt.124.267795","DOIUrl":"https://doi.org/10.2967/jnmt.124.267795","url":null,"abstract":"<p><p>Asymmetric hot spots in the axial skeleton on bone scintigraphy may confound diagnosis. We describe an unexpected artifact of <sup>99m</sup>Tc-methylene diphosphonate near the breast in a 55-y-old woman with breast cancer. The initial whole-body bone scintigraphy revealed a solitary focal lesion in the anterior ribs on the left side. After careful tracking, we determined that this hot spot originated from the adhesive bandage. The patient had placed it in her left front pocket after removing it from the injection site. She was rescanned after the bandage had been removed from her pocket.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141633673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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