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Journal of nuclear medicine technology最新文献

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Prominent Right Ventricular Tracer Uptake: A Harbinger of Multivessel Coronary Artery Disease. 右心室示踪剂摄取突出：多支冠状动脉疾病的先兆。
IF 1
Journal of nuclear medicine technology Pub Date : 2025-06-04 DOI: 10.2967/jnmt.125.270002
Adam Adam, Saurabh Malhotra
{"title":"Prominent Right Ventricular Tracer Uptake: A Harbinger of Multivessel Coronary Artery Disease.","authors":"Adam Adam, Saurabh Malhotra","doi":"10.2967/jnmt.125.270002","DOIUrl":"10.2967/jnmt.125.270002","url":null,"abstract":"<p><p>A 65-y-old woman with multiple cardiovascular risk factors presented with atypical chest pain, prompting a 1-d pharmacologic stress myocardial perfusion test using <sup>99m</sup>Tc sestamibi. Initial interpretation suggested ischemia, but closer inspection revealed increased right ventricular uptake and increased left ventricular chamber size at stress, indicative of significant 3-vessel coronary artery disease (CAD). These findings were confirmed by cardiac catheterization, showing 3-vessel disease, including significant left main CAD. The patient underwent coronary artery bypass graft surgery. This case highlights the importance of meticulous SPECT image interpretation, particularly focusing on right ventricular uptake and transient ischemic dilation, to accurately diagnose severe CAD and improve cardiovascular outcomes.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"172-173"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lung Ventilation: Technegas. 肺通气：tecnegas。
IF 1
Journal of nuclear medicine technology Pub Date : 2025-06-04 DOI: 10.2967/jnmt.125.269769
Tina M Buehner
{"title":"Lung Ventilation: Technegas.","authors":"Tina M Buehner","doi":"10.2967/jnmt.125.269769","DOIUrl":"10.2967/jnmt.125.269769","url":null,"abstract":"","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"183"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12175976/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SPECT/CT for Discrimination Between Active and Inactive Os Trigonum in Posterior Ankle Syndrome. 后踝关节综合征中活跃与不活跃三角肌的SPECT/CT鉴别。
IF 1
Journal of nuclear medicine technology Pub Date : 2025-06-04 DOI: 10.2967/jnmt.124.269284
Michael Pöhlmann, Martin Freesmeyer, Falk Gühne
{"title":"SPECT/CT for Discrimination Between Active and Inactive Os Trigonum in Posterior Ankle Syndrome.","authors":"Michael Pöhlmann, Martin Freesmeyer, Falk Gühne","doi":"10.2967/jnmt.124.269284","DOIUrl":"10.2967/jnmt.124.269284","url":null,"abstract":"<p><p>[<sup>99m</sup>Tc]-3,3-diphosphono-1,2-propanodicarboxylic acid bone scintigraphy was used to differentiate between posterior impingement syndrome and Haglund syndrome in a 34-y-old man with unclear right-sided ankle pain. The patient had an accessory os trigonum bilaterally, and previous x-ray, MRI, and CT were inconclusive. Using SPECT/CT with new iterative reconstruction algorithms based on CT images, the pathologic activation of bone metabolism at the right-sided os trigonum and the adjacent talus joint was revealed. Other causes of posterior ankle pain were ruled out, and posterior impingement syndrome was diagnosed.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"178-179"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phase I Study of 68Ga-NOTA-HL for PET/CT Imaging of Hepatic Asialoglycoprotein Receptors in Healthy Volunteers. 68Ga-NOTA-HL用于健康志愿者肝亚糖糖蛋白受体PET/CT成像的一期研究。
IF 1
Journal of nuclear medicine technology Pub Date : 2025-06-04 DOI: 10.2967/jnmt.124.268430
Ching-Liang Kuo, Rhoh-Fang Yen, Yao-Ming Wu, Mei-Hui Wang
{"title":"Phase I Study of <sup>68</sup>Ga-NOTA-HL for PET/CT Imaging of Hepatic Asialoglycoprotein Receptors in Healthy Volunteers.","authors":"Ching-Liang Kuo, Rhoh-Fang Yen, Yao-Ming Wu, Mei-Hui Wang","doi":"10.2967/jnmt.124.268430","DOIUrl":"10.2967/jnmt.124.268430","url":null,"abstract":"<p><p>This study investigated the safety, biodistribution, and dosimetry of <sup>68</sup>Ga-hexavalent lactoside (<sup>68</sup>Ga-NOTA-HL), a PET tracer targeting asialoglycoprotein receptors (ASGPRs) on hepatocytes. ASGPRs, key for glycoprotein homeostasis, serve as a valuable biomarker of liver function. <sup>68</sup>Ga-NOTA-HL demonstrated excellent safety in 12 healthy volunteers with no adverse events. Biodistribution studies revealed high liver uptake with minimal uptake in other organs, consistent with ASGPR targeting. The effective dose was 0.0289 mSv/MBq, indicating low radiation exposure. These findings suggest <sup>68</sup>Ga-NOTA-HL PET/CT holds significant promise as a safe and effective imaging technique for assessing liver function. The high liver specificity and extremely low background activity provide a strong foundation for further clinical investigations into its potential for evaluating liver function in various clinical settings, including the assessment of liver reserve in patients with liver diseases.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"152-157"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143997168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardiac Sarcoidosis Imaging: PET. 心脏结节病影像学：PET。
IF 1
Journal of nuclear medicine technology Pub Date : 2025-06-04 DOI: 10.2967/jnmt.125.269838
Diane K Soulek, Mary Beth Farrell, Kathy S Thomas, Eleanor S Mantel, Jessica Settle
{"title":"Cardiac Sarcoidosis Imaging: PET.","authors":"Diane K Soulek, Mary Beth Farrell, Kathy S Thomas, Eleanor S Mantel, Jessica Settle","doi":"10.2967/jnmt.125.269838","DOIUrl":"10.2967/jnmt.125.269838","url":null,"abstract":"","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"113-115"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143763989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metastatic Mimicker in Thyroid Cancer with Thyroglobulin Elevation and an FDG-Avid Recurrent Aneurysmal Bone Cyst. 甲状腺癌伴甲状腺球蛋白升高和fdg复发性动脉瘤性骨囊肿的转移模拟因子。
IF 1
Journal of nuclear medicine technology Pub Date : 2025-06-04 DOI: 10.2967/jnmt.124.269415
Piyush Aggarwal, Yamini Mathur, Ashwani Sood, Rajender Kumar, Bhagwant Rai Mittal
{"title":"Metastatic Mimicker in Thyroid Cancer with Thyroglobulin Elevation and an FDG-Avid Recurrent Aneurysmal Bone Cyst.","authors":"Piyush Aggarwal, Yamini Mathur, Ashwani Sood, Rajender Kumar, Bhagwant Rai Mittal","doi":"10.2967/jnmt.124.269415","DOIUrl":"10.2967/jnmt.124.269415","url":null,"abstract":"<p><p>Many benign bone lesions mimic skeletal metastases from thyroid cancer on imaging and even may have high metabolic uptake on <sup>18</sup>F-FDG PET/CT. It becomes crucial to distinguish these hypermetabolic lesions (benign vs. metastasis), especially in patients with thyroglobulin elevation and negative iodine scan. The index case describes a patient with thyroid cancer having thyroglobulin elevation and negative iodine scan with a hypermetabolic aneurysmal bone cyst mimicking skeletal metastasis.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"176-177"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Motion Artifacts in SPECT Myocardial Perfusion Imaging. SPECT心肌灌注成像中的运动伪影。
IF 1
Journal of nuclear medicine technology Pub Date : 2025-06-04 DOI: 10.2967/jnmt.125.269853
Sara G Johnson
{"title":"Motion Artifacts in SPECT Myocardial Perfusion Imaging.","authors":"Sara G Johnson","doi":"10.2967/jnmt.125.269853","DOIUrl":"10.2967/jnmt.125.269853","url":null,"abstract":"","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"138-139"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Single- Versus Dual-Time-Point Imaging for Transthyretin Cardiac Amyloid Using 99mTc-Pyrophosphate. 使用99mtc焦磷酸盐对转甲状腺素心脏淀粉样蛋白进行单时间点与双时间点成像。
IF 1
Journal of nuclear medicine technology Pub Date : 2025-06-04 DOI: 10.2967/jnmt.124.269395
Wesley Ng, Kunthi Pathmaraj, Natalia Kovaleva, Aurora Poon, Peter Kench, Steven Meikle, Andrew Scott, Raef Boktor
{"title":"Single- Versus Dual-Time-Point Imaging for Transthyretin Cardiac Amyloid Using <sup>99m</sup>Tc-Pyrophosphate.","authors":"Wesley Ng, Kunthi Pathmaraj, Natalia Kovaleva, Aurora Poon, Peter Kench, Steven Meikle, Andrew Scott, Raef Boktor","doi":"10.2967/jnmt.124.269395","DOIUrl":"10.2967/jnmt.124.269395","url":null,"abstract":"<p><p>Nuclear medicine scintigraphy using <sup>99m</sup>Tc-pyrophosphate has proven valuable in the diagnosis of cardiac transthyretin amyloidosis in recent years. However, there is still confusion over the optimal imaging time points. The American Society of Nuclear Cardiology has recommended different imaging time points over the last decade. We aimed to determine whether single- or dual-time-point imaging is required for reporting purposes and which time point would be the most appropriate if a single time point was to be considered. <b>Methods:</b> Cardiac amyloid scans using <sup>99m</sup>Tc-pyrophosphate acquired from 2017 to 2023 were retrieved from our Picture Archiving and Communications System. Scans with static views and SPECT/CT images of the chest for both imaging time points, at 1 h (early) and 3 h (delayed) after injection, were included. Each study was independently read by 3 nuclear medicine physicians. Original clinical reports using both imaging time points were used as a reference to calculate the accuracy of a single time point. <b>Results:</b> In total, 70 patients were included in this study. Reports of cardiac amyloid studies using any single-time-point imaging were highly sensitive, accurate, and specific. There was agreement among all readers. Of the 140 datasets reported by each reader, 4 scans were classified as equivocal, requiring more imaging for confident reporting. <b>Conclusion:</b> Single-time-point imaging showed an accuracy comparable to the dual-time-point imaging in diagnosing cardiac transthyretin amyloidosis. This was further validated by agreement among the 3 readers. Early time-point imaging is preferred, and additional delayed imaging can be acquired when the early result is equivocal.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"140-145"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143968142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
18F-FDG Myocardial Uptake Related to Continuous Venovenous Hemodialysis: The Importance of Eliminating All Things Sweet. 与持续静脉-静脉血液透析相关的18F-FDG心肌摄取：排除所有甜食的重要性。
IF 1
Journal of nuclear medicine technology Pub Date : 2025-06-04 DOI: 10.2967/jnmt.124.268968
Reja E A Schaaf, Hein J Verberne, Dave A Dongelmans
{"title":"<sup>18</sup>F-FDG Myocardial Uptake Related to Continuous Venovenous Hemodialysis: The Importance of Eliminating All Things Sweet.","authors":"Reja E A Schaaf, Hein J Verberne, Dave A Dongelmans","doi":"10.2967/jnmt.124.268968","DOIUrl":"10.2967/jnmt.124.268968","url":null,"abstract":"<p><p>When <sup>18</sup>F-FDG PET/CT is used to diagnose cardiovascular inflammation or infection, it is important to differentiate between pathologic and physiologic <sup>18</sup>F-FDG myocardial uptake. Several methods to suppress physiologic <sup>18</sup>F-FDG myocardial uptake have been reported, all based on the principle of promoting free fatty acid metabolism over glucose metabolism. However, despite rigorous implementation of these protocols, there is variation in successful myocardial glucose suppression. Sometimes this variation can be explained by specific patient conditions or treatment regimes. Here, we describe a patient on continuous venovenous hemodialysis with <sup>18</sup>F-FDG myocardial uptake despite adequate preparation.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"174-175"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can an Abnormal Gastric Emptying Study Be Normal? 胃排空异常能正常吗？
IF 1
Journal of nuclear medicine technology Pub Date : 2025-06-04 DOI: 10.2967/jnmt.124.269182
Ben Freiberg
{"title":"Can an Abnormal Gastric Emptying Study Be Normal?","authors":"Ben Freiberg","doi":"10.2967/jnmt.124.269182","DOIUrl":"10.2967/jnmt.124.269182","url":null,"abstract":"<p><p>The American Neurogastroenterology and Motility Society and the Society of Nuclear Medicine and Molecular Imaging collaboratively wrote consensus statements to standardize gastric emptying scintigraphy. Despite this, centers are using nonstandard protocols. This study examined how these protocols contrast with standards. <b>Methods:</b> Consecutive charts were analyzed for meal, radionuclide dose, half-emptying time (T½) and its normal range, and documented retention and emptying. Impressions were compared with how emptying mapped on a graph based on standard 4-h values. <b>Results:</b> Thirty-four studies were identified. Ten of 14 abnormal studies were normal when plotted on the standard 4-h graph. Eight of 10 abnormal studies had normal 2- or 4-h retention. Normal T½ ranges varied significantly. Most altered the meal, and over 25% received a radionucleotide dose outside the recommended range. <b>Conclusion:</b> The upper bound of normal T½ falls within standard 4-h bounds, with many individuals given an erroneous impression. Though further optimization may be needed, adhering to standards is critical.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"158-161"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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