Journal of nuclear medicine technology最新文献

Delivery Methods of Radiopharmaceuticals: Exploring Global Strategies to Minimize Occupational Radiation Exposure. 放射性药物的给药方法：探索将职业辐射暴露降至最低的全球战略。

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Journal of nuclear medicine technology Pub Date : 2024-11-12 DOI: 10.2967/jnmt.124.268043

Hinna Shahid, Lois Miller, Obaid Kazmi, Peter Seidensticker

{"title":"Delivery Methods of Radiopharmaceuticals: Exploring Global Strategies to Minimize Occupational Radiation Exposure.","authors":"Hinna Shahid, Lois Miller, Obaid Kazmi, Peter Seidensticker","doi":"10.2967/jnmt.124.268043","DOIUrl":"https://doi.org/10.2967/jnmt.124.268043","url":null,"abstract":"In the world of nuclear medicine, health care professionals face the challenge of safeguarding themselves and their patients from occupational radiation exposure. As the field experiences exponential growth, driven by the surge in approvals of radiopharmaceuticals for diagnostic and therapeutic applications, it becomes vital to delve into the delivery methods of radiopharmaceuticals. Health care professionals take precautions during radiopharmaceutical administration, including maintaining distance from radioactive sources, using shielding, limiting exposure time, and monitoring radiation levels with badges. Regular evaluations provide compliance with recommended exposure limits, yet concerns persist, especially regarding the cumulative radiation exposure from manual injections over time. Understanding the long-term effects of radiation exposure has spurred the development of cutting-edge medical device technologies, such as autoinjectors, designed to administer radiopharmaceuticals accurately while minimizing total radiation dose to health care professionals. The U.S. Pharmacopeia 825 regulation refers to these devices as \"direct infusion systems.\" Nuclear medicine technologists commonly refer to them as \"autoinjectors,\" whereas device manufacturers may use terms such as injection system, radiopharmaceutical injector, or infusion system. Despite variations in terminology, these devices hold a pivotal role in shaping the future of radiopharmaceutical delivery. In an era of escalating demand for PET procedures worldwide, skilled health care professionals ensure the safe and precise dosing of radiopharmaceuticals. This article explores the state-of-the-art medical devices in radiopharmaceutical delivery, spotlighting transformative medical devices currently revolutionizing the nuclear medicine landscape in the global market.","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142621933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Decoding the Jargon: Understanding the Nomenclature of Clinical Education. 解码术语：了解临床教育术语。

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Journal of nuclear medicine technology Pub Date : 2024-11-12 DOI: 10.2967/jnmt.124.268576

Sara L Johnson

引用次数: 0

Reply to "SPECT Views for Cardiac Amyloidosis Imaging". 回复 "心脏淀粉样变性成像的 SPECT 观察"。

IF 1

Journal of nuclear medicine technology Pub Date : 2024-11-12 DOI: 10.2967/jnmt.124.269000

Mary Beth Farrell

引用次数: 0

PET Imaging in Alzheimer Disease: Pathology and Research Insights for Technologists. 阿尔茨海默病的 PET 成像：病理学和技术人员的研究启示。

IF 1

Journal of nuclear medicine technology Pub Date : 2024-11-12 DOI: 10.2967/jnmt.124.268916

Charisse Gentry, Michael Malek-Ahmadi, Susan Bolas, Jose Pena

{"title":"PET Imaging in Alzheimer Disease: Pathology and Research Insights for Technologists.","authors":"Charisse Gentry, Michael Malek-Ahmadi, Susan Bolas, Jose Pena","doi":"10.2967/jnmt.124.268916","DOIUrl":"https://doi.org/10.2967/jnmt.124.268916","url":null,"abstract":"Alzheimer disease (AD) is the sixth leading cause of death in the United States and is projected to affect over 13 million people by the year 2060. Although there is currently no cure for AD, disease-modifying treatments that target amyloid plaques have recently been approved for use. The advent of PET tracers that can reliably detect the presence of cortical amyloid plaques and tau pathologies has allowed researchers and clinicians to identify individuals who have pathologic markers of AD before the onset of cognitive decline. Although these tracers have been widely used in research settings for some time, they are now on the verge of being used to aid clinicians in the differential diagnosis of AD. As the use of these tracers increases, technologists will need to be educated on the best practices and potential problems they may encounter in their clinical populations. This article will review the available tracers for amyloid and tau PET scans and educate technologists about the most important practices and procedures that can be implemented to ensure patient safety and the capture of high-quality scans.","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142622006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brain Imaging-PET: Tau. 脑成像-PET：Tau.

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Journal of nuclear medicine technology Pub Date : 2024-11-12 DOI: 10.2967/jnmt.124.268995

Mary Beth Farrell, Kathy S Thomas, Eleanor S Mantel, Jessica Settle

引用次数: 0

SPECT Views for Cardiac Amyloidosis Imaging. 心脏淀粉样变性成像的 SPECT 观察。

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Journal of nuclear medicine technology Pub Date : 2024-11-12 DOI: 10.2967/jnmt.124.268369

Jennifer Prekeges

引用次数: 0

Amyloid Imaging Update: How the Amyloid Landscape Is Changing in Light of the Recent Food and Drug Administration Approval of Antiamyloid Therapeutics. 淀粉样蛋白成像最新进展：淀粉样蛋白前景如何因食品药品管理局近期批准抗淀粉样蛋白治疗药物而发生变化。

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Journal of nuclear medicine technology Pub Date : 2024-11-12 DOI: 10.2967/jnmt.124.268329

Barbara J Grabher

{"title":"Amyloid Imaging Update: How the Amyloid Landscape Is Changing in Light of the Recent Food and Drug Administration Approval of Antiamyloid Therapeutics.","authors":"Barbara J Grabher","doi":"10.2967/jnmt.124.268329","DOIUrl":"https://doi.org/10.2967/jnmt.124.268329","url":null,"abstract":"It has been some time since the Journal of Nuclear Medicine and Technology has published an article on best practices in amyloid imaging. In light of the recent Food and Drug Administration approval of new antiamyloid therapies (AATs) to decrease amyloid plaques in the brain and slow progression of mild cognitive impairment, and the potential increase in the number of amyloid PET scans being acquired to document amyloid plaques, the Journal of Nuclear Medicine and Technology felt it was a perfect time to publish a refresher on best practices. AATs are administered to help slow progression of mild cognitive impairment, allowing patients to live independently a little longer before having to give up their independence and move in with family or into an assisted living facility. Neurologists prescribing AATs must first document that the patient has amyloid plaques. To do this, amyloid PET can be performed, or a lumbar puncture can be used to look for amyloid plaques in the cerebrospinal fluid. Although the latter is more cost-effective and has no associated radiation exposure, it is highly invasive compared with amyloid PET. High-quality amyloid PET scans interpretated by a trained nuclear medicine physician are the first step and key to providing the dementia expert and patient with accurate information on amyloid status, allowing for the best decisions on patient management.","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142621681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brain Imaging: Amyloid-β PET. 脑成像：淀粉样蛋白-β PET。

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Journal of nuclear medicine technology Pub Date : 2024-10-22 DOI: 10.2967/jnmt.124.268854

Mary Beth Farrell

引用次数: 0

Gender and Ethnicity Bias of Text-to-Image Generative Artificial Intelligence in Medical Imaging, Part 2: Analysis of DALL-E 3. 医学影像中文本到图像生成人工智能的性别和种族偏差，第 2 部分：《DALL-E 3》分析。

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Journal of nuclear medicine technology Pub Date : 2024-10-22 DOI: 10.2967/jnmt.124.268359

Geoffrey Currie, Johnathan Hewis, Elizabeth Hawk, Eric Rohren

{"title":"Gender and Ethnicity Bias of Text-to-Image Generative Artificial Intelligence in Medical Imaging, Part 2: Analysis of DALL-E 3.","authors":"Geoffrey Currie, Johnathan Hewis, Elizabeth Hawk, Eric Rohren","doi":"10.2967/jnmt.124.268359","DOIUrl":"https://doi.org/10.2967/jnmt.124.268359","url":null,"abstract":"Disparity among gender and ethnicity remains an issue across medicine and health science. Only 26%-35% of trainee radiologists are female, despite more than 50% of medical students' being female. Similar gender disparities are evident across the medical imaging professions. Generative artificial intelligence text-to-image production could reinforce or amplify gender biases. Methods: In March 2024, DALL-E 3 was utilized via GPT-4 to generate a series of individual and group images of medical imaging professionals: radiologist, nuclear medicine physician, radiographer, nuclear medicine technologist, medical physicist, radiopharmacist, and medical imaging nurse. Multiple iterations of images were generated using a variety of prompts. Collectively, 120 images were produced for evaluation of 524 characters. All images were independently analyzed by 3 expert reviewers from medical imaging professions for apparent gender and skin tone. Results: Collectively (individual and group images), 57.4% (n = 301) of medical imaging professionals were depicted as male, 42.4% (n = 222) as female, and 91.2% (n = 478) as having a light skin tone. The male gender representation was 65% for radiologists, 62% for nuclear medicine physicians, 52% for radiographers, 56% for nuclear medicine technologists, 62% for medical physicists, 53% for radiopharmacists, and 26% for medical imaging nurses. For all professions, this overrepresents men compared with women. There was no representation of persons with a disability. Conclusion: This evaluation reveals a significant overrepresentation of the male gender associated with generative artificial intelligence text-to-image production using DALL-E 3 across the medical imaging professions. Generated images have a disproportionately high representation of white men, which is not representative of the diversity of the medical imaging professions.","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142502306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Rare Case of Orbital Metastasis from Invasive Lobular Carcinoma: Challenges of ¹⁸F-FDG PET/CT and the Search for Consensus on Imaging. 一例罕见的浸润性肺叶癌眼眶转移病例：18F-FDG PET/CT 的挑战与寻求成像共识。

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Journal of nuclear medicine technology Pub Date : 2024-10-22 DOI: 10.2967/jnmt.124.267732

Marjorie Lam, Johnny Yang, Vani Vijayakumar

{"title":"A Rare Case of Orbital Metastasis from Invasive Lobular Carcinoma: Challenges of 18F-FDG PET/CT and the Search for Consensus on Imaging.","authors":"Marjorie Lam, Johnny Yang, Vani Vijayakumar","doi":"10.2967/jnmt.124.267732","DOIUrl":"https://doi.org/10.2967/jnmt.124.267732","url":null,"abstract":"Invasive lobular carcinoma (ILC) frequently underlies orbital metastasis. A 74-y-old woman, who was current with mammograms and had no cancer history, presented to her ophthalmologist with visual complaints and was found to have metastatic ILC. MRI was contraindicated, and an 18F-FDG PET/CT scan revealed a mildly hypermetabolic right orbital mass and low uptake in the left subareolar breast, suggestive of metastatic ILC. Small studies have found that in ILC, 16α-18F-fluoroestradiol and fibroblast activation protein inhibitors are more avid than 18F-FDG. There is currently no consensus regarding imaging for ILC. Many people have contraindications to MRI, and the higher rate of false-negative findings on mammography for ILC than for other breast cancers makes this patient population more vulnerable to inaccurate staging, incorrect assessment of tumor burden, and, consequently, insufficient treatment. We provide this interesting case to highlight the potential of 18F-fluoroestradiol PET/CT and fibroblast activation protein inhibitors over 18F-FDG in this breast cancer subtype.","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142502303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0