Sunil R Selvin, Erin Stevens, Mary Beth Farrell, Gary V Heller
{"title":"Patient Motion During Cardiac PET Imaging.","authors":"Sunil R Selvin, Erin Stevens, Mary Beth Farrell, Gary V Heller","doi":"10.2967/jnmt.125.269911","DOIUrl":"10.2967/jnmt.125.269911","url":null,"abstract":"<p><p>Cardiac PET imaging is increasingly used for myocardial perfusion studies because of its high diagnostic accuracy and low radiation exposure to the patient. However, patient motion can be challenging, affecting a large number of studies. Motion artifacts can lead to inconclusive or false-positive results, complicating clinical interpretation. This article explores the causes of motion artifacts and their characteristic appearance in cardiac PET imaging, highlighting their distinction from true perfusion abnormalities. Strategies for minimizing motion through effective patient positioning and communication are discussed. Understanding and addressing motion artifacts are crucial for optimizing diagnostic accuracy and ensuring the full benefit of cardiac PET imaging.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"135-137"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Empowering Technologists, Elevating Care.","authors":"Julie Dawn Bolin","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":"53 2","pages":"7A-8A"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144225751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Myocardial Sympathetic Innervation Imaging.","authors":"Justin G Peacock, Mary Beth Farrell","doi":"10.2967/jnmt.125.270093","DOIUrl":"10.2967/jnmt.125.270093","url":null,"abstract":"","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"101-103"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12175993/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143987769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kara Weatherman, Erin Elizabeth Grady, Nic Mastascusa, Sara Johnson, George H Hinkle, Richard Laforest, Chloee Wendorf, Kathy S Thomas
{"title":"The SNMMI/ACNM Practice Guideline for the Use of Radiopharmaceuticals 5.0.","authors":"Kara Weatherman, Erin Elizabeth Grady, Nic Mastascusa, Sara Johnson, George H Hinkle, Richard Laforest, Chloee Wendorf, Kathy S Thomas","doi":"10.2967/jnmt.125.269834","DOIUrl":"10.2967/jnmt.125.269834","url":null,"abstract":"","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"130-134"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Justin G Peacock, Haley Majot, Avani T Bansal, Patrick Neshiwat, Kelsy Dimeff, Kalpna Prasad
{"title":"Illuminating the Hidden: Standardizing Cardiac MIBG Imaging for Sympathetic Dysfunction.","authors":"Justin G Peacock, Haley Majot, Avani T Bansal, Patrick Neshiwat, Kelsy Dimeff, Kalpna Prasad","doi":"10.2967/jnmt.124.269436","DOIUrl":"10.2967/jnmt.124.269436","url":null,"abstract":"<p><p>The heart's innervation relies on a delicate balance between the sympathetic and parasympathetic nervous systems, each using distinct neurotransmitters to regulate heart rate, contractility, and vascular tone. The sympathetic division primarily uses norepinephrine, whereas the parasympathetic division operates through acetylcholine. A range of diseases, through intrinsic and extrinsic mechanisms, can disrupt these neural pathways, resulting in autonomic dysfunction. This review highlights intrinsic causes such as dysautonomias, amyloidosis, diabetes mellitus, Parkinsonian syndromes, and Lewy body dementia, as well as extrinsic factors such as heart failure, myocardial ischemia, infarction, and drug-induced cardiotoxicity. This article examines the effects of various conditions on cardiac sympathetic innervation and highlights how <sup>123</sup>I-radiolabeled metaiodobenzylguanidine (MIBG), a norepinephrine analog, can target the cardiac sympathetic nervous system for early detection and disease characterization. Currently, variability in cardiac <sup>123</sup>I-MIBG imaging protocols across institutions leads to inconsistencies in image acquisition and interpretation, limiting the establishment of universal benchmarks for distinguishing normal from abnormal cardiac sympathetic innervation. To address this, we propose a simple, clinically useful, standardized protocol based on European Association of Nuclear Medicine guidelines and the AdreView Myocardial Imaging for Risk Evaluation in Heart Failure trial, incorporating both qualitative and semiquantitative methods for disease assessment and highlight cutoff values for some pathologies that can assist in visual interpretation. Standardizing these protocols will enhance the consistency, reliability, and diagnostic accuracy of <sup>123</sup>I-MIBG imaging, improving clinical decision-making and optimizing patient outcomes.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"90-100"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12176009/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144030394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Geoffrey Currie, Johnathan Hewis, Elizabeth Hawk, Eric Rohren
{"title":"Gender and Ethnicity Bias of Text-to-Image Generative Artificial Intelligence in Medical Imaging, Part 2: Analysis of DALL-E 3.","authors":"Geoffrey Currie, Johnathan Hewis, Elizabeth Hawk, Eric Rohren","doi":"10.2967/jnmt.124.268359","DOIUrl":"10.2967/jnmt.124.268359","url":null,"abstract":"<p><p>Disparity among gender and ethnicity remains an issue across medicine and health science. Only 26%-35% of trainee radiologists are female, despite more than 50% of medical students' being female. Similar gender disparities are evident across the medical imaging professions. Generative artificial intelligence text-to-image production could reinforce or amplify gender biases. <b>Methods:</b> In March 2024, DALL-E 3 was utilized via GPT-4 to generate a series of individual and group images of medical imaging professionals: radiologist, nuclear medicine physician, radiographer, nuclear medicine technologist, medical physicist, radiopharmacist, and medical imaging nurse. Multiple iterations of images were generated using a variety of prompts. Collectively, 120 images were produced for evaluation of 524 characters. All images were independently analyzed by 3 expert reviewers from medical imaging professions for apparent gender and skin tone. <b>Results:</b> Collectively (individual and group images), 57.4% (<i>n</i> = 301) of medical imaging professionals were depicted as male, 42.4% (<i>n</i> = 222) as female, and 91.2% (<i>n</i> = 478) as having a light skin tone. The male gender representation was 65% for radiologists, 62% for nuclear medicine physicians, 52% for radiographers, 56% for nuclear medicine technologists, 62% for medical physicists, 53% for radiopharmacists, and 26% for medical imaging nurses. For all professions, this overrepresents men compared with women. There was no representation of persons with a disability. <b>Conclusion:</b> This evaluation reveals a significant overrepresentation of the male gender associated with generative artificial intelligence text-to-image production using DALL-E 3 across the medical imaging professions. Generated images have a disproportionately high representation of white men, which is not representative of the diversity of the medical imaging professions.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"162-168"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142502306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Improvement of Anatomic Alignment and Image Quality Using a Respiratory Motion Reduction Block in Oncologic PET/CT.","authors":"Hajime Ichikawa, Takayuki Shibutani, Toyohiro Kato, Tomoya Banno, Mitsuaki Terabe, Hideki Shimada","doi":"10.2967/jnmt.124.269096","DOIUrl":"10.2967/jnmt.124.269096","url":null,"abstract":"<p><p><sup>18</sup>F-FDG PET/CT is crucial for cancer diagnosis; however, respiratory motion often causes misregistration between PET and CT images. This study aimed to evaluate the impact of a custom-made respiratory motion reduction block (RRB) in reducing misregistration and improving image quality in <sup>18</sup>F-FDG PET/CT. <b>Methods:</b> The RRB was developed to minimize the effects of respiratory motion. It is a pentagonal block made of Styrofoam designed to compress the upper abdomen. This study included 170 patients who underwent whole-body <sup>18</sup>F-FDG PET/CT. Patients were categorized into 4 groups based on the CT and PET scanning technique used: a control free-breathing (FB) group (breath-holding [BH] CT without RRB and respiration-gated [RG] PET), a control RG group (BH CT without RRB with RG PET), a BH RRB group (BH CT with RRB), and a FB RRB group (FB CT with RRB). Various parameters, including the incidence rate and distance of anatomic misregistration, and signal-to-noise ratio, were measured and compared. <b>Results:</b> For the control FB, control RG, BH RRB, and FB RRB groups, the incidence rates of anatomic misregistration between PET and CT images were 47.1%, 27.5%, 34.0%, and 16.7%, respectively. The mean misregistration distances in these groups were 5.1 ± 6.0, 3.1 ± 5.5, 3.8 ± 6.2, and 1.3 ± 3.2 mm, respectively. Furthermore, the RRB improved the signal-to-noise ratio of the liver. <b>Conclusion:</b> The RRB effectively improved registration between PET and CT images. Our approach is cost-effective and provides respiratory motion suppression not only during PET but also during CT scans. The use of RRB with FB PET scanning was found to be more beneficial than respiratory gating.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"146-151"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recognizing and Responding to the Acute Cardiac Stress Patient.","authors":"Geoffrey Currie, Hosen Kiat","doi":"10.2967/jnmt.125.269450","DOIUrl":"10.2967/jnmt.125.269450","url":null,"abstract":"<p><p>A cardiac emergency in SPECT/CT and PET/CT occurs infrequently but necessitates prompt recognition and an appropriate response. The emergence of <sup>18</sup>F-based myocardial perfusion radiopharmaceuticals is anticipated to increase the use of cardiac stress testing; therefore, it is crucial for personnel, including nuclear medicine technologists in PET departments, to be equipped with proper training and competency to identify and manage deteriorating cardiac patients or emergency cardiac events. This article provides insight into the foundation principles of both cardiac stress testing and the use of adjunctive medications to manage patients after stress. The acute deteriorating nuclear cardiology patient is outlined, including recognizing crucial changes in vital signs and basic electrocardiogram interpretation. Key medications associated with an emergency response are detailed. Armed with these tools, nuclear medicine technologists can more confidently care for high-risk nuclear cardiology patients.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"116-122"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Technegas Ventilation Lung Imaging in the United States.","authors":"Kathy S Thomas, Tina M Buehner","doi":"10.2967/jnmt.125.269774","DOIUrl":"10.2967/jnmt.125.269774","url":null,"abstract":"","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"180-182"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PET/CT Case Series: Unmasking the Mystery of Cardiac Sarcoidosis.","authors":"Diane K Soulek","doi":"10.2967/jnmt.125.269732","DOIUrl":"10.2967/jnmt.125.269732","url":null,"abstract":"<p><p>The annual incidence of cardiac sarcoidosis is low, but increased awareness of this inflammatory condition has led to earlier disease recognition. High mortality rates compel prompt diagnosis and intervention to reduce the risk of major adverse cardiac events. This cardiac sarcoid PET/CT case series provides information on cardiac sarcoid features, reviews advanced imaging and its role in treatment monitoring, examines the importance of dietary modifications required for <sup>18</sup>F-FDG cardiac sarcoid imaging and the associated consequences of noncompliant patient preparation, and provides an in-depth review of a patient's cardiac sarcoid journey.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"104-112"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}