Journal of nuclear medicine technology最新文献

{"title":"Improvement of Anatomic Alignment and Image Quality Using a Respiratory Motion Reduction Block in Oncologic PET/CT.","authors":"Hajime Ichikawa, Takayuki Shibutani, Toyohiro Kato, Tomoya Banno, Mitsuaki Terabe, Hideki Shimada","doi":"10.2967/jnmt.124.269096","DOIUrl":"https://doi.org/10.2967/jnmt.124.269096","url":null,"abstract":"<p><p>¹⁸F-FDG PET/CT is crucial for cancer diagnosis; however, respiratory motion often causes misregistration between PET and CT images. This study aimed to evaluate the impact of a custom-made respiratory motion reduction block (RRB) in reducing misregistration and improving image quality in ¹⁸F-FDG PET/CT. <b>Methods:</b> The RRB was developed to minimize the effects of respiratory motion. It is a pentagonal block made of Styrofoam designed to compress the upper abdomen. This study included 170 patients who underwent whole-body ¹⁸F-FDG PET/CT. Patients were categorized into 4 groups based on the CT and PET scanning technique used: a control free-breathing (FB) group (breath-holding [BH] CT without RRB and respiration-gated [RG] PET), a control RG group (BH CT without RRB with RG PET), a BH RRB group (BH CT with RRB), and a FB RRB group (FB CT with RRB). Various parameters, including the incidence rate and distance of anatomic misregistration, and signal-to-noise ratio, were measured and compared. <b>Results:</b> For the control FB, control RG, BH RRB, and FB RRB groups, the incidence rates of anatomic misregistration between PET and CT images were 47.1%, 27.5%, 34.0%, and 16.7%, respectively. The mean misregistration distances in these groups were 5.1 ± 6.0, 3.1 ± 5.5, 3.8 ± 6.2, and 1.3 ± 3.2 mm, respectively. Furthermore, the RRB improved the signal-to-noise ratio of the liver. <b>Conclusion:</b> The RRB effectively improved registration between PET and CT images. Our approach is cost-effective and provides respiratory motion suppression not only during PET but also during CT scans. The use of RRB with FB PET scanning was found to be more beneficial than respiratory gating.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recognizing and Responding to the Acute Cardiac Stress Patient.","authors":"Geoffrey Currie, Hosen Kiat","doi":"10.2967/jnmt.125.269450","DOIUrl":"https://doi.org/10.2967/jnmt.125.269450","url":null,"abstract":"<p><p>A cardiac emergency in SPECT/CT and PET/CT occurs infrequently but necessitates prompt recognition and an appropriate response. The emergence of ¹⁸F-based myocardial perfusion radiopharmaceuticals is anticipated to increase the use of cardiac stress testing; therefore, it is crucial for personnel, including nuclear medicine technologists in PET departments, to be equipped with proper training and competency to identify and manage deteriorating cardiac patients or emergency cardiac events. This article provides insight into the foundation principles of both cardiac stress testing and the use of adjunctive medications to manage patients after stress. The acute deteriorating nuclear cardiology patient is outlined, including recognizing crucial changes in vital signs and basic electrocardiogram interpretation. Key medications associated with an emergency response are detailed. Armed with these tools, nuclear medicine technologists can more confidently care for high-risk nuclear cardiology patients.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Technegas Ventilation Lung Imaging in the United States.","authors":"Kathy S Thomas, Tina M Buehner","doi":"10.2967/jnmt.125.269774","DOIUrl":"https://doi.org/10.2967/jnmt.125.269774","url":null,"abstract":"","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"¹⁸F-FDG Myocardial Uptake Related to Continuous Venovenous Hemodialysis: The Importance of Eliminating All Things Sweet.","authors":"Reja E A Schaaf, Hein J Verberne, Dave A Dongelmans","doi":"10.2967/jnmt.124.268968","DOIUrl":"https://doi.org/10.2967/jnmt.124.268968","url":null,"abstract":"<p><p>When ¹⁸F-FDG PET/CT is used to diagnose cardiovascular inflammation or infection, it is important to differentiate between pathologic and physiologic ¹⁸F-FDG myocardial uptake. Several methods to suppress physiologic ¹⁸F-FDG myocardial uptake have been reported, all based on the principle of promoting free fatty acid metabolism over glucose metabolism. However, despite rigorous implementation of these protocols, there is variation in successful myocardial glucose suppression. Sometimes this variation can be explained by specific patient conditions or treatment regimes. Here, we describe a patient on continuous venovenous hemodialysis with ¹⁸F-FDG myocardial uptake despite adequate preparation.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Cardiac Sarcoidosis with PET/CT.","authors":"Alexander Liu, Lionel T Munemo, Nuno Martins, Vasileios Kouranos, Athol U Wells, Rakesh K Sharma, Kshama Wechalekar","doi":"10.2967/jnmt.124.268142","DOIUrl":"https://doi.org/10.2967/jnmt.124.268142","url":null,"abstract":"<p><p>¹⁸F-FDG PET with CT is an important advanced imaging modality used to assess patients with suspected or known cardiac sarcoidosis (CS). ¹⁸F-FDG PET is indicated for CS work-up in patients with extra-CS and abnormal screening results for cardiac involvement, patients under 60 y old presenting with unexplained high-grade atrioventricular heart block, and patients with suspected CS and idiopathic ventricular arrhythmias. In patients with established CS, serial ¹⁸F-FDG PET can be used to assess response to immunosuppressive therapy and long-term surveillance for reactivation of myocardial inflammation in patients with low-grade or quiescent disease. Patient preparation before ¹⁸F-FDG PET scanning is key in ensuring adequate suppression of physiologic myocardial ¹⁸F-FDG uptake, to maximize the power of the test to detect pathology. Inadequate dietary preparation can cause diffuse or focal-on-diffuse ¹⁸F-FDG uptake in the absence of active inflammation. It is important to assess resting myocardial perfusion, typically with ⁸²Rb cardiac PET. Several different patterns of abnormalities have been reported in patients with CS, including normal myocardial perfusion with focal or patchy ¹⁸F-FDG uptake suggesting myocardial inflammation without scarring; the presence of a myocardial perfusion defect with abnormal ¹⁸F-FDG uptake suggesting myocardial scarring with inflammation; and the presence of a myocardial perfusion defect without ¹⁸F-FDG uptake indicating myocardial scarring without inflammation. Prognostically, the presence of myocardial perfusion defects and abnormal ¹⁸F-FDG uptake has been shown to be an independent predictor of death or ventricular arrythmias. A high myocardial SUV_max in the left and right ventricles has been shown to be an independent predictor of adverse clinical outcomes. Although the diagnostic performance of ¹⁸F-FDG PET has been studied, the reference standard for CS tended to rely on clinical criteria, which may be less sensitive than ¹⁸F-FDG PET at detecting CS. Therefore, the diagnosis of CS should rely on a multidisciplinary team approach involving multimodality advanced imaging, including echocardiography, cardiovascular MR, and ¹⁸F-FDG PET.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Monitored Walking on Extracardiac Intestinal Activity in Myocardial Perfusion Imaging.","authors":"Anja Strok, Maja Dolenc Novak, Barbara Guzic Salobir, Monika Stalc, Katja Zaletel","doi":"10.2967/jnmt.124.267917","DOIUrl":"10.2967/jnmt.124.267917","url":null,"abstract":"<p><p>Various techniques have been used in attempts to reduce interfering gastrointestinal activity in myocardial perfusion imaging (MPI); however, these approaches have yielded inconsistent results. The goal of this study was to investigate the efficacy of monitored walking, a previously unexplored technique, in reducing subdiaphragmatic activity-related artifacts during pharmacologic stress ^99mTc-tetrofosmin MPI with SPECT to improve the overall image quality. <b>Methods:</b> The study included patients who underwent MPI with pharmacologic stress. They were given a step counter immediately after the radiotracer injection and were randomized into a group A, with a request to walk at least 1,000 steps before imaging, and a group B, with no specific instructions about walking. The reconstructed SPECT images were assessed visually. Moderate and severe levels of subdiaphragmatic tracer activity were considered relevant for the interpretation of the scans. Additionally, myocardial and abdominal activity was semiquantitatively assessed on raw planar images, and the mean myocardium-to-abdomen count ratios were calculated. <b>Results:</b> We enrolled 199 patients (95 patients in group A and 104 patients in group B). Clinical characteristics did not differ significantly between the 2 groups. Patients in group A walked more steps than patients in group B (<i>P</i> < 0.001), but there were no differences in the proportion of accepted scans between the 2 groups (<i>P</i> = 0.41). Additionally, there were no differences in the proportion of relevant subdiaphragmatic activity between the groups (<i>P</i> = 0.91). The number of steps did not impact the acceptance rate (<i>P</i> = 0.29). <b>Conclusion:</b> A higher number of steps walked during the waiting period between pharmacologic stress and acquisition does not affect subdiaphragmatic activity-related artifacts or the proportion of accepted scans after pharmacologic stress. However, pedometer use and clear instructions motivate patients to walk while awaiting imaging. Larger studies are required to compare a higher-step-count group with a sedentary control group to assess the influence of walking on gastrointestinal artifacts in MPI.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"331-336"},"PeriodicalIF":1.0,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142289486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SNMMI-TS Nuclear Medicine Technology Universal AES/CI Handbook.","authors":"Sara L Johnson, Matthew J Ugorowski, Crystal Botkin, Danielle Deimer, Julie Dawn Bolin, Sarah A Frye, Regina M Garrard, David Kelkis, Jennifer L Prekeges, Dusty M York, Lauren Shanbrun, Ann M Voslar, Norma Green Gutierrez, Courtney Cross, Jane E Kamm","doi":"10.2967/jnmt.124.268858","DOIUrl":"10.2967/jnmt.124.268858","url":null,"abstract":"","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":"52 4","pages":"285-298"},"PeriodicalIF":1.0,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142780317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Ectopic Kidney Located at the Deep Subcutaneous Region of the Abdominal Wall: Role of Diuretic Renography with ^99mTc-DTPA.","authors":"Rahul V Parghane, Sandip Basu","doi":"10.2967/jnmt.124.267908","DOIUrl":"10.2967/jnmt.124.267908","url":null,"abstract":"<p><p>An ectopic kidney is often found inadvertently during CT, ultrasonography, MRI, or urologic physical examination. Ectopic kidneys usually occur in the pelvis. A pelvic ectopic kidney may be misinterpreted for a pelvic tumor by less experienced physicians and surgeons. We present an extremely rare case of ectopic kidney in the deep subcutaneous region of the abdominal wall and associated with the additional abnormality of spina bifida. MRI found an ectopic kidney but failed to identify ureteropelvic drainage. Diuretic renography with ^99mTc-diethylenetriaminepentaacetic acid showed normal functioning and identified nonobstructive ureteropelvic drainage of the ectopic subcutaneous kidney.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"367-368"},"PeriodicalIF":1.0,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141432147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Single Hepatic Metastasis of Cranial Meningioma on [¹⁸F]FDG PET/CT 16 Years After Initial Surgery.","authors":"Yan Cui, Xin Zhou, Nan Li","doi":"10.2967/jnmt.124.267905","DOIUrl":"10.2967/jnmt.124.267905","url":null,"abstract":"<p><p>Hepatic metastases of cranial meningiomas are rare, particularly when they present as a delayed, solitary metastasis, which poses a challenge for imaging-based diagnosis. [¹⁸F]FDG PET/CT facilitates diagnosis and posttreatment restaging, whereas somatostatin receptor-targeted PET demonstrates high sensitivity and specificity in the diagnosis of meningiomas and may potentially evaluate the viability of theranostics approaches, particularly for treatment-resistant meningiomas.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"362-363"},"PeriodicalIF":1.0,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adrenal Oncocytoma: A Rare Tumor with Conflicting Imaging Features.","authors":"Parneet Singh, Girish Kumar Parida, Tejasvini Singhal, Pavithra Ayyanar, Kishore Kumar Behera, Kanhaiyalal Agrawal, Pritinanda Mishra, P Sai Sradha Patro","doi":"10.2967/jnmt.124.267465","DOIUrl":"10.2967/jnmt.124.267465","url":null,"abstract":"<p><p>Oncocytic adenomas are rare benign tumors that typically originate in organs such as the kidneys, thyroid, parathyroid, salivary glands, or pituitary gland. Oncocytic adenoma of the adrenal gland is extremely rare. It often shows heterogeneous, nonspecific features on anatomic imaging, as well as high ¹⁸F-FDG avidity despite its benign nature. The definitive diagnosis relies on histopathologic examination, including immunohistochemistry. We present an incidentally detected benign adrenal oncocytic adenoma with intense ¹⁸F-FDG uptake mimicking sinister pathologies.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"364-366"},"PeriodicalIF":1.0,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}