Journal of neonatal-perinatal medicine最新文献

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Correlation of predelivery Rotational Thromboelastometry readings with the risk of postpartum hemorrhage during delivery: The ROTEM Study. 产前旋转血栓弹性测量读数与分娩期间产后出血风险的相关性:ROTEM研究。
Journal of neonatal-perinatal medicine Pub Date : 2025-01-01 Epub Date: 2024-11-03 DOI: 10.1177/19345798241291327
Joaquin A Calderon, Ahmed M Ebeid, Sean M Lee, Homa K Ahmadzia
{"title":"Correlation of predelivery Rotational Thromboelastometry readings with the risk of postpartum hemorrhage during delivery: The ROTEM Study.","authors":"Joaquin A Calderon, Ahmed M Ebeid, Sean M Lee, Homa K Ahmadzia","doi":"10.1177/19345798241291327","DOIUrl":"10.1177/19345798241291327","url":null,"abstract":"<p><p>BackgroundInconsistency in defining postpartum hemorrhage (PPH), and the inability of current tools and approaches to accurately predict PPH have led to the exploration of innovative methods. Rotational thromboelastometry (ROTEM) point-of-care technology provides real-time assessment of the clotting process facilitating time-efficient hemostatic interventions. Our study investigates the utility of ROTEM parameters for predicting individual risk of PPH.MethodsThis multi-site, prospective observational cohort study recruited 92 women who underwent scheduled cesarean delivery and normal spontaneous vaginal delivery at university-affiliated hospitals from 2018 to 2023. We included women between 18 and 50 years old at ≥34 weeks of gestation. Subjects were approached in the hospital pre-admission testing unit during their routine pre-operative blood draws, typically at least 72 h in advance of their planned cesarean delivery. Participants were also enrolled at the hospital once they arrived for admission a few hours before their procedure. ROTEM parameters EXTEM clotting time (CT), clot formation time (CFT), alpha angle, A10, A20, maximum clot formation (MCF), maximum lysis, were measured preoperative.ResultsWe found significant effects of age, blood loss type, delivery mode, gestational age, and maximum lysis on blood loss. The reduced model predicted that every one-percent increase in maximum lysis was associated with a 44-milliliter increase in blood loss and every one-year increase in age was associated with a 19-milliliter increase in blood loss. On average, cesarean deliveries resulted in 522 more milliliters of blood loss than normal spontaneous vaginal delivery.ConclusionThe ROTEM EXTEM maximum lysis parameter has a significant effect on blood loss. Larger prospective clinical trials in conjunction with a prompt definition of the ranges of reference values will strengthen these advances to provide a rapid assessment and guide early interventions to prevent severe obstetric bleeding.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":" ","pages":"18-24"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atypical presentation of a common condition. 一种常见疾病的非典型表现。
Journal of neonatal-perinatal medicine Pub Date : 2025-01-01 Epub Date: 2025-02-05 DOI: 10.1177/19345798251315389
Mariana Oliveira Pereira, Rita Lages Pereira, Fábia Carvalho, Liliana Pinheiro, Filipa Neiva
{"title":"Atypical presentation of a common condition.","authors":"Mariana Oliveira Pereira, Rita Lages Pereira, Fábia Carvalho, Liliana Pinheiro, Filipa Neiva","doi":"10.1177/19345798251315389","DOIUrl":"10.1177/19345798251315389","url":null,"abstract":"<p><p>Cow's milk protein allergy (CMPA) presents a wide range of clinical manifestations. Although gastrointestinal symptoms are common, they are not always present. In this report, we present two cases of infants with atypical CMPA presentations. Case 1 involves a male newborn who was admitted with polyarthritis and a target-shaped rash, while case 2 features a female newborn who presented with soft swelling of extremities. Both infants had recently started using infant formula, which raised CMPA's suspicion. An extensively hydrolyzed formula (eHF) was introduced, resulting in the resolution of symptoms, with positive specific IgE measurements supporting the diagnosis. Further, in case 2, she underwent an oral provocation test that confirmed the diagnosis. These cases underscore the clinical variability of CMPA, which can present diagnostic challenges. While specific IgE measurements can offer valuable supporting information, a clinical diagnosis remains indispensable. Awareness of the diverse presentations and a thorough patient history are critical for accurate diagnosis and the prevention of unnecessary treatments.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":" ","pages":"94-97"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Concordance of maternal and cord blood SARS-COV-2 immunoglobulin seropositivity after COVID-19 infection or vaccination in pregnancy. COVID-19感染或妊娠期接种疫苗后孕产妇和脐带血SARS-COV-2免疫球蛋白血清阳性的一致性
Journal of neonatal-perinatal medicine Pub Date : 2025-01-01 Epub Date: 2025-02-05 DOI: 10.1177/19345798251315385
Gladys Rojas, Aarti Jain, Fayez Bany-Mohammed, Philip Felgner, Muhammad Aslam, Cherry C Uy
{"title":"Concordance of maternal and cord blood SARS-COV-2 immunoglobulin seropositivity after COVID-19 infection or vaccination in pregnancy.","authors":"Gladys Rojas, Aarti Jain, Fayez Bany-Mohammed, Philip Felgner, Muhammad Aslam, Cherry C Uy","doi":"10.1177/19345798251315385","DOIUrl":"10.1177/19345798251315385","url":null,"abstract":"<p><p>ObjectiveTo assess maternal antibody response to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection during pregnancy and subsequent transplacental antibody transfer in cord blood.Study DesignThis is a prospective cohort study of Coronavirus Disease 2019 (COVID-19) polymerase chain reaction (PCR) positive pregnant women and their newborns. SARS-CoV-2 PCR (+) women were enrolled, with SARS-CoV-2 PCR (-) as control. Maternal blood was obtained at enrollment and cord blood collected at delivery. Baseline maternal and infant characteristics and neonatal outcomes were collected. Samples were analyzed using coronavirus antigen microarray containing immunologically significant antigens from SARS-CoV-2 (including nucleocapsid protein [NP], spike protein [S], S1, S2, receptor-binding domain [RBD]) which can detect SARS-CoV-2 immunoglobulin G (IgG) and immunoglobulin M (IgM).ResultsThirty-seven maternal-cord blood paired samples were analyzed for SARS-CoV-2 IgG or IgM antibodies; 15 out of 20 samples from SARS-CoV-2 PCR (+) and 14 out of 17 from SARS-CoV-2 PCR (-) mothers were IgG positive. 14 out of the 17 SARS-CoV-2 PCR (-) mothers received COVID-19 vaccine during pregnancy. Difference between IgG seropositivity of naturally infected versus vaccinated mothers were significant, 75% versus 100% (<i>p</i> = 0.043). IgM antibodies were detected in 10 out of 20 SARS-CoV-2 PCR (+) women but none were detected in cord blood.ConclusionsExcellent concordance of SARS-CoV-2 IgG antibodies exist between maternal and cord blood. Significantly higher SARS-COV-2 cord blood IgG seropositivity was found in vaccinated versus naturally infected mothers.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":" ","pages":"9-17"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12231836/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Breastfeeding initiation according to the severity of Class 3 obesity. 根据3级肥胖的严重程度开始母乳喂养。
Journal of neonatal-perinatal medicine Pub Date : 2025-01-01 Epub Date: 2024-11-01 DOI: 10.1177/19345798241296331
Leandro Cordero, Michael R Stenger, Mark B Landon, Bradley J Needleman, Sabrena Noria, Craig A Nankervis
{"title":"Breastfeeding initiation according to the severity of Class 3 obesity.","authors":"Leandro Cordero, Michael R Stenger, Mark B Landon, Bradley J Needleman, Sabrena Noria, Craig A Nankervis","doi":"10.1177/19345798241296331","DOIUrl":"10.1177/19345798241296331","url":null,"abstract":"<p><p><b>Background:</b> Class 3 obesity is composed of <i>morbid</i> (BMI 40-49 kg/m<sup>2</sup>) and <i>extreme</i> (BMI ≥ 50 kg/m<sup>2</sup>) subgroups. Adverse perinatal outcomes have been associated with obesity; however, data on breastfeeding (BF) initiation for women in either group remains limited.<b>Objective:</b> To compare BF initiation rates (exclusive or partial BF) and related comorbidities of 890 women with <i>morbid</i> and 890 with <i>extreme</i> obesity matched by race, parity, and year of delivery.<b>Methods:</b> Retrospective cohort study of women who delivered singletons at ≥ 34 weeks gestation (2013-2021). Those who had bariatric surgery or infants with major malformations were excluded.<b>Results:</b> Both groups were similar in: primiparity (38%), age (29y), white race (58%), African American (36%), current (10 vs 12%) and former (25 vs 27%) smokers, gestational hypertension (15 vs 16%), polycystic ovary syndrome (5 vs 7%), gastroesophageal reflux disease (10 vs 10%), and anemia (17 vs 17%). Women in the <i>extreme</i> group had a higher prevalence of gestational (17 vs 12%) and pregestational diabetes (12 vs 6%), chronic hypertension (41 vs 17%), severe preeclampsia (18 vs 12%), obstructive sleep apnea (12 vs 3%), asthma (22 vs 16%), and cesarean deliveries (62 vs 44%). Intention to BF (64 vs 71%), exclusive BF (23 vs 34%), and BF initiation (57 vs 64%) rates were lower in the <i>extreme</i> obesity group at discharge.<b>Conclusion:</b> Higher frequency of comorbidities in the <i>extreme</i> obesity group highlights the need for antenatal, intrapartum, and postpartum targeted interventions if the benefits of BF to mothers and infants are to be realized.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":" ","pages":"70-78"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of lung ultrasound score in early prediction of bronchopulmonary dysplasia in preterm neonates. 肺超声评分在早期预测早产儿支气管肺发育不良中的作用。
Journal of neonatal-perinatal medicine Pub Date : 2025-01-01 Epub Date: 2024-11-08 DOI: 10.1177/19345798241296329
Shikha Khandelwal, Vikram Datta, Rama Anand, Narendra Babu Devabathina
{"title":"Role of lung ultrasound score in early prediction of bronchopulmonary dysplasia in preterm neonates.","authors":"Shikha Khandelwal, Vikram Datta, Rama Anand, Narendra Babu Devabathina","doi":"10.1177/19345798241296329","DOIUrl":"10.1177/19345798241296329","url":null,"abstract":"<p><p>BackgroundThe use of lung ultrasound score (LUS) to predict bronchopulmonary dysplasia (BPD) is still evolving. While LUS is widely available and accurate, there is limited evidence from low- and middle-income countries. We aim to assess LUS's predictive ability for BPD in preterm neonates less than 30 weeks gestation.Material and methodsWe enrolled 160 neonates born at <30 weeks of gestation, who required any form of respiratory support at least for 24 h. Six zone LUS was calculated for all the neonates first within 72 h and then weekly till 36 weeks of post-menstrual age (PMA) or discharge, whichever was earlier. After excluding death and missed scans, 112 neonates were categorized as BPD or non-BPD and were analysed for their LUS.ResultNeonates who developed BPD (<i>n</i> = 33) had higher LUS from the first assessment up to nine weeks. An LUS >5 could predict the development of BPD at one week with a sensitivity of 87.88%, specificity 89.87%, and area under ROC Curve (AUC) 0.93, and at two weeks with a sensitivity of 78.79%, specificity of 96.2%, and AUC 0.95. Likewise, at three and four weeks of life, the optimum cutoff of LUS >3 and >2, respectively, predicted the development of BPD with sensitivity 93.99%, specificity 94.94%, and AUC 0.97 at three weeks and sensitivity 87.88%, specificity 92.41 %, and AUC 91.07% at four weeks. Prediction for moderate-severe BPD was also reliable at all scan time points with AUC 0.84 at 1-3 days, 0.91 at one week, 0.92 at two weeks, 0.95 at three weeks, and 0.97 at four weeks, with LUS cutoff >8, >5, >6, >4, and >3, respectively.ConclusionLUS can reliably predict the future development of BPD as early as one week of life and can play an important role in optimizing BPD preventive strategies.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":" ","pages":"52-60"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extremely preterm infant with double aortic arch presenting with severe tracheal obstruction and devastating esophageal hemorrhage. 有双主动脉弓的极早产儿,表现为严重的气管阻塞和毁灭性的食管出血。
Journal of neonatal-perinatal medicine Pub Date : 2025-01-01 Epub Date: 2025-02-04 DOI: 10.1177/19345798251315387
Ryosuke Kanamori, Tomoaki Nomura, Akira Hirose, Hiroki Ito, Masaya Yamoto, Norie Mitsushita, Reiji Nakano
{"title":"Extremely preterm infant with double aortic arch presenting with severe tracheal obstruction and devastating esophageal hemorrhage.","authors":"Ryosuke Kanamori, Tomoaki Nomura, Akira Hirose, Hiroki Ito, Masaya Yamoto, Norie Mitsushita, Reiji Nakano","doi":"10.1177/19345798251315387","DOIUrl":"10.1177/19345798251315387","url":null,"abstract":"<p><p><b>Background:</b> Double aortic arch is the most constrictive type of vascular ring, completely encircling the trachea and esophagus, and can cause severe respiratory failure, dysphagia, or devastating esophageal hemorrhage. Although surgical repair is usually recommended shortly after diagnosis, surgery in extremely preterm infants presents significant challenges. The optimal timing of surgery and the management of complications that arise while awaiting surgery are not well understood.<b>Case presentation:</b> We report the case of an Asian female infant weighing 509 g at 24 + 5 weeks of gestation with a double aortic arch. Initially managed conservatively to allow for growth, the patient developed progressive tracheal granulation and recurrent, life-threatening esophageal hemorrhage. Gastrostomy and division of the vascular ring were successfully performed on days 65 and 66 (postmenstrual age 33 weeks; weight 1126 g), and tracheal granulation was managed conservatively. Despite mild respiratory symptoms persisting, the patient survived until discharge without any recurrence of esophageal bleeding.<b>Conclusion:</b> The management of double aortic arch in extremely preterm infants is particularly challenging. In this case, surgical repair was successfully performed at a weight of 1126 g without lethal postoperative complications. Early gastrostomy before the surgical repair of the double aortic arch may be advantageous in preventing devastating esophageal hemorrhage, especially in patients with severe tracheal narrowing indicative of a tight vascular ring and significant esophageal compression.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":" ","pages":"89-93"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of vasopressin infusion in refractory neonatal shock. 抗利尿激素输注治疗难治性新生儿休克的效果。
Journal of neonatal-perinatal medicine Pub Date : 2025-01-01 Epub Date: 2024-10-30 DOI: 10.1177/19345798241296327
Anup Thakur, Sachin Dangi, Rohit Gehlawat, Neelam Kler, Pankaj Garg, Anurag Fursule
{"title":"Effect of vasopressin infusion in refractory neonatal shock.","authors":"Anup Thakur, Sachin Dangi, Rohit Gehlawat, Neelam Kler, Pankaj Garg, Anurag Fursule","doi":"10.1177/19345798241296327","DOIUrl":"10.1177/19345798241296327","url":null,"abstract":"<p><p><b>Background</b>To evaluate the effect of vasopressin infusion in refractory neonatal shock.MethodThis was a cohort study involving retrospective review of medical records of all neonates who received intravenous vasopressin infusion for at least 6 h for treatment of refractory shock in a level 3B neonatal intensive care unit of northern India between Jan 2016 to May 2021. Outcome measures assessed were systolic, diastolic, and mean blood pressure, heart rate, urine output, serum sodium level, inotrope score, and oxygenation index at 6, 12, 24, 48, and 72 h of vasopressin therapy. Outcome measures were compared before (T1) and 48 h (T2) after initiation of vasopressin.ResultsA total of 32 neonates received vasopressin. The mean (SD) systolic, diastolic, and mean blood pressure improved significantly between T1 and T2 from 54 (9) to 64 (11) mm Hg (MD (95% CI) = 10.3 (4.2-16.6), <i>p</i> = 0.003), 36 (8) to 42 (10) mm Hg (MD (95% CI) = 6.2 (1.3-11.3), <i>p</i> = 0.01), and 43 (8) to 51 (10) mm Hg (MD (95% CI) = 8.5 (2.3-14.6), <i>p</i> = 0.01), respectively. Median (IQR) urine output improved from 1.25 (0-3.2) to 2.1 (1.6-7) ml/kg/hr, <i>p</i> = 0.004. There was a significant fall in serum sodium from 139 (9) to 134 (8) mEq/l, <i>p</i> = 0.01. Out of 32 infants, 19 (59.4%) survived, while 6 (18.8 %) were transferred out and 7 (21.8%) died.ConclusionVasopressin improved hemodynamic parameters in refractory neonatal shock and can be used as a rescue therapy. Vasopressin therapy is associated with a fall in serum sodium.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":" ","pages":"86-88"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of neonatal intensive care unit design on infants with Neonatal Opioid Withdrawal Syndrome. 新生儿重症监护病房设计对新生儿阿片类戒断综合征的影响。
Journal of neonatal-perinatal medicine Pub Date : 2025-01-01 Epub Date: 2024-11-05 DOI: 10.1177/19345798241296324
Katherine Nyman, Elyse Decker, Kristin Ronan, Mathangi Gopalakrishnan, Dina El-Metwally
{"title":"Effect of neonatal intensive care unit design on infants with Neonatal Opioid Withdrawal Syndrome.","authors":"Katherine Nyman, Elyse Decker, Kristin Ronan, Mathangi Gopalakrishnan, Dina El-Metwally","doi":"10.1177/19345798241296324","DOIUrl":"10.1177/19345798241296324","url":null,"abstract":"<p><p>Background/ObjectiveNeonatal Opioid Withdrawal Syndrome (NOWS) requires advanced and often prolonged medical care in the neonatal intensive care unit (NICU). We examined the effect of NICU design on treatment and NICU length of stay (NICU-LOS) for infants with NOWS.MethodsA retrospective chart review of eligible infants with NOWS was conducted from 2013 to 2018. We collected and analyzed data on demographics, medication, and NICU-LOS characteristics. A multivariable linear regression on log-transformed NICU-LOS was performed for comparison between the open-bay design (OBD) for 2013-2015 (August) and the new single-family-room (SFR) NICU for September 2015-2018.ResultsThere were 118 neonates analyzed in OBD and 138 neonates in the SFR. Among infants in the SFR NICU, 86% received pharmacotherapy, compared to 76% of infants in the OBD (<i>p</i> = 0.059). The breastfeeding rate was 26% in the SFR and 6% in the OBD (<i>p</i> =< 0.001 ). Infants in the SFR NICU had 1.3 times longer mean NICU-LOS (<i>p</i> = 0.0163) than infants in OBD after adjusting for covariates including small for gestational age. The median (1Q, 3Q) cumulative doses of morphine (mg/kg) among the SFR and OBD groups were 6.4 (2.3,17.3) and 8.7 (3.2,19.3) <i>p</i>: NS, respectively.ConclusionsThe SFR NICU was associated with longer NICU-LOS for infants with NOWS despite higher rates of breastfeeding and no difference in morphine dosage. While providing more privacy and possible improved patient satisfaction, there may be unintended consequences of the SFR design.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":" ","pages":"46-51"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early versus delayed inguinal hernia repair in preterm infants: A systematic review and meta-analysis. 早产儿腹股沟疝早期修复与延迟修复:一项系统回顾和荟萃分析。
Journal of neonatal-perinatal medicine Pub Date : 2025-01-01 Epub Date: 2025-02-13 DOI: 10.1177/19345798251318594
Henrique Provinciatto, Marcus Vinicius Barbosa Moreira, Lucas Rezende de Freitas, Edward Araujo Júnior
{"title":"Early versus delayed inguinal hernia repair in preterm infants: A systematic review and meta-analysis.","authors":"Henrique Provinciatto, Marcus Vinicius Barbosa Moreira, Lucas Rezende de Freitas, Edward Araujo Júnior","doi":"10.1177/19345798251318594","DOIUrl":"10.1177/19345798251318594","url":null,"abstract":"<p><p>BackgroundWe aimed to perform a systematic review and updated meta-analysis evaluating the optimal timing for repairing inguinal hernia in preterm infants.MethodsCochrane Central, Embase, and PubMed were searched from inception to April 2024 for studies comparing early versus delayed repair of inguinal hernia in preterm infants, without applying filters or language limitations. We utilized the RStudio version 4.2.2 to compute risk ratios with random effects for our prespecified outcomes.ResultsIn our study, which encompassed 1207 patients from eight studies, 676 (56%) preterm patients underwent early repair for inguinal hernia. Although we found no significant association between early repair and incarceration (risk ratio, 1.14; 95% Confidence Intervals, 0.76-1.70; <i>p</i> = 0.52; I<sup>2</sup> = 19%), there was an increased risk of recurrence with early repair in comparison with delayed management (risk ratio, 3.11; 95% Confidence Intervals, 1.17-8.25; <i>p</i> = 0.02; I<sup>2</sup> = 0%).ConclusionOur findings suggest postponing the repair of inguinal hernia in preterm infants until after hospitalization to avoid the potential increased risk of recurrence and respiratory complications associated with early repair.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":" ","pages":"3-8"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post-traumatic stress disorder in mother's of children hospitalized in the neonatal intensive care. 新生儿重症监护中儿童母亲创伤后应激障碍
Journal of neonatal-perinatal medicine Pub Date : 2025-01-01 Epub Date: 2024-10-29 DOI: 10.1177/19345798241290966
Mohamed Sellouti, Aomar Agadr, Rachid Abilkassem
{"title":"Post-traumatic stress disorder in mother's of children hospitalized in the neonatal intensive care.","authors":"Mohamed Sellouti, Aomar Agadr, Rachid Abilkassem","doi":"10.1177/19345798241290966","DOIUrl":"10.1177/19345798241290966","url":null,"abstract":"<p><p><b>Background:</b> The progress of neonatal intensive care units has notably enhanced the chances of survival for infants. Despite this, post-traumatic stress disorder (PTSD) in mothers of neonates receiving care in the Neonatal Intensive Care Units (NICU) remains a widely underestimated issue.<b>Aims and objectives:</b> Our objective was to pinpoint the possible risk factors contributing to the development of post-traumatic stress disorder in mothers of neonates receiving care in the NICU.<b>Methods:</b> A prospective, descriptive study was carried out at the Mohamed V Moroccan Military teaching hospital over a 1-year period from January 1st, 2023, to December 31st, 2023, concentrating on neonatal medicine and resuscitation. Mothers were interviewed, and the presence of PTSD after preterm birth and NICU admission was assessed using the Clinician Administered PTSD Scale (CAPS) at 28-30 days following NICU admission or at the time of discharge.<b>Results:</b> The findings revealed that mothers of premature infants displayed more stress symptoms compared to mothers of full-term newborns. Through multivariate analysis, we observed that the gestational age of newborns admitted to the NICU significantly (<i>p</i> = 0.001) influenced the occurrence of PTSD.<b>Conclusion:</b> Post-traumatic stress disorder in mothers of preterm newborns is a pathological condition that demands proper management from the very first days after birth. The NICU environment remains a significant risk factor for PTSD.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":" ","pages":"32-35"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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