Y Zheng, Y Almeyda-Alejo, D Tumin, N S J Redpath, J Guillen-Hernandez
{"title":"Three or four doses of intravenous immunoglobulin G treatment for isoimmune hemolytic disease: A case series and literature review.","authors":"Y Zheng, Y Almeyda-Alejo, D Tumin, N S J Redpath, J Guillen-Hernandez","doi":"10.3233/NPM-230070","DOIUrl":"10.3233/NPM-230070","url":null,"abstract":"<p><strong>Background: </strong>Neonates affected by isoimmune hemolytic disease (HDN) are at risk of developing severe hyperbilirubinemia. Studies show that increasing levels of bilirubin impact neonatal neurodevelopment. To avoid complications associated with exchange transfusion, intravenous immunoglobulin G (IVIG) is used to treat hyperbilirubinemia. We included all infants who received more than two doses of IVIG treatment for isoimmune hemolytic disease. We analyzed the incidence of side effects associated with IVIG treatment and the rate of exchange transfusion.</p><p><strong>Methods: </strong>A retrospective chart review performed between October 2011-October 2022 at East Carolina University Health identified neonates who received more than two doses IVIG for HDN. Neonates of postmenstrual age greater than 28 days old, receiving less than three doses of IVIG or received IVIG for other indications were excluded. The occurrences of adverse events, demographics and use of other medical therapies were reviewed.</p><p><strong>Results: </strong>Eleven neonates were included in the case series. Most common cause of severe hyperbilirubinemia was attributed to ABO incompatibility. Six patients (54%) received three doses of IVIG, and five patients (45%) received four doses of IVIG with bilirubin levels decreasing below exchange transfusion. No treatment exceeding four doses of IVIG was reported, nor adverse events during treatment.</p><p><strong>Conclusions: </strong>In this cohort of neonates with HDN, bilirubin levels decreased after treatment with multiple doses of IVIG. Future research on recommendations of optimal total number doses of IVIG to reduce the risk for exchange transfusion.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":" ","pages":"153-158"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139032414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ceyda Acun, Collins Akugizibwe, Hany Aly, Alexa AschAlexander Avian, Nur Aycan, Nariae Baik-Schneditz, Sean Bailey, Vera Balog, Magdolna Barra, Ellen Bartolini, Murat Basaranoglu, Priska Bauerstätter, Angel Bazan, Angelika Berger, James P Boardman, Geraldine Boylan, Marlies Bruckner, Jenny Bua, Julia Buchmayer, Martha Caprio, Sara Cherkerzian, Venkata Chirumammilla, Helen Christou, Derya Cay Demir, Eugene M Dempsey, Mohamed El-Dib, Julia Elis, Hoda El-Shibiny, Isaac Emurang, Michael J Esser, German Figueroa, Daragh Finn, Maria Angela Franceschini, Hans Fuchs, Aisling Garvey, Vito Giordano, Katharina Goeral, Seth Goldstein, Rathinaswamy B Govindan, Ellen Grant, Kerstin Gründler, Marlene Hammer, Katie Hannon, Balazs Hauser, Chuan-Heng Hsiao, Imran Ilahi, Terrie Inder, Agnes Jermendy, Pauline De Jesus, Edith Mbabazi Kabachelor, Enock Kainja, Serap Karaman, Sreenivas Karnati, Lukasz Karpinski, Gregor Kasprian, Miriah Kemigisha Katugi, Janine Khan, Ursula Kiechl-Kohlendorfer, Seh Hyun Kim, Melinda Kis-Tamas, Katrin Klebermass-Schrehof, Lisa Klein, Lilijana Kornhauser-Cerar, Georg Langs, Luca Laura Bogner, Rakesh Lavu, Brenda Law, Pei-Yi Lin, Gianluca Lista, Wei Liu, Vicki Livingstone, Joshua Magombe, Sean Mathieson, Lukas Mileder, Khorshid Mohammad, Michael Moore, Ronald Mulondo, Chelsea Munster, Deirdre Murray, Esther Nalule, Davis Natukwatsa, Nicholas Nicoletti, Christa Nöhammer, Tatiana Nuzum, Simeo Ochieng, Mandana O'Donnell, Monika Olischar, Silvia Orlandi, John O'Toole, Anna Lucia Paltrinieri, Andrea Pardo, Andreea Pavel, Tina Perme, Daniel Pfurtscheller, Gerhard Pichler, Cara Pleau, Ana Laguna Pradas, Sandra Pusil, Subhash Puthuraya, Ajay Rajaram, Dimitrios Rallis, Braulio Ramírez, Alam Randhawa, Nicola J Robertson, Sandra Pusil, Steven Schiff, Sarah Schlatterer, Christoph Schlatzer, Georg M Schmölzer, Silvia Schönthaler, Bernhard Schwaberger, Christoph E Schwarz, Marvin Seruwu, Laila Springer, Mirjam Steiner, Ilaria Stucchi, John Sunwoo, Jason Sutin, Miklos Szabo, Eniko Szakmar, Tomasz Szczapa, Julia Tatz, Starlin Tindimwebwa, Sarolta H Trinh, Oguz Tuncer, Helen L Turner, Berndt Urlesberger, Klemens Vierlinger, Gabriel A Vignolle, Rutvi Vyas, Moses Wabukoma, Elena Wachtel, Benjamin Warf, Michael Woglom, Christina H Wolfsberger, Kristine Woodward, Eyyup Yurekturk
{"title":"Proceedings of the 15th International Newborn Brain Conference: Other forms of brain monitoring, such as NIRS, fMRI, biochemical, etc.","authors":"Ceyda Acun, Collins Akugizibwe, Hany Aly, Alexa AschAlexander Avian, Nur Aycan, Nariae Baik-Schneditz, Sean Bailey, Vera Balog, Magdolna Barra, Ellen Bartolini, Murat Basaranoglu, Priska Bauerstätter, Angel Bazan, Angelika Berger, James P Boardman, Geraldine Boylan, Marlies Bruckner, Jenny Bua, Julia Buchmayer, Martha Caprio, Sara Cherkerzian, Venkata Chirumammilla, Helen Christou, Derya Cay Demir, Eugene M Dempsey, Mohamed El-Dib, Julia Elis, Hoda El-Shibiny, Isaac Emurang, Michael J Esser, German Figueroa, Daragh Finn, Maria Angela Franceschini, Hans Fuchs, Aisling Garvey, Vito Giordano, Katharina Goeral, Seth Goldstein, Rathinaswamy B Govindan, Ellen Grant, Kerstin Gründler, Marlene Hammer, Katie Hannon, Balazs Hauser, Chuan-Heng Hsiao, Imran Ilahi, Terrie Inder, Agnes Jermendy, Pauline De Jesus, Edith Mbabazi Kabachelor, Enock Kainja, Serap Karaman, Sreenivas Karnati, Lukasz Karpinski, Gregor Kasprian, Miriah Kemigisha Katugi, Janine Khan, Ursula Kiechl-Kohlendorfer, Seh Hyun Kim, Melinda Kis-Tamas, Katrin Klebermass-Schrehof, Lisa Klein, Lilijana Kornhauser-Cerar, Georg Langs, Luca Laura Bogner, Rakesh Lavu, Brenda Law, Pei-Yi Lin, Gianluca Lista, Wei Liu, Vicki Livingstone, Joshua Magombe, Sean Mathieson, Lukas Mileder, Khorshid Mohammad, Michael Moore, Ronald Mulondo, Chelsea Munster, Deirdre Murray, Esther Nalule, Davis Natukwatsa, Nicholas Nicoletti, Christa Nöhammer, Tatiana Nuzum, Simeo Ochieng, Mandana O'Donnell, Monika Olischar, Silvia Orlandi, John O'Toole, Anna Lucia Paltrinieri, Andrea Pardo, Andreea Pavel, Tina Perme, Daniel Pfurtscheller, Gerhard Pichler, Cara Pleau, Ana Laguna Pradas, Sandra Pusil, Subhash Puthuraya, Ajay Rajaram, Dimitrios Rallis, Braulio Ramírez, Alam Randhawa, Nicola J Robertson, Sandra Pusil, Steven Schiff, Sarah Schlatterer, Christoph Schlatzer, Georg M Schmölzer, Silvia Schönthaler, Bernhard Schwaberger, Christoph E Schwarz, Marvin Seruwu, Laila Springer, Mirjam Steiner, Ilaria Stucchi, John Sunwoo, Jason Sutin, Miklos Szabo, Eniko Szakmar, Tomasz Szczapa, Julia Tatz, Starlin Tindimwebwa, Sarolta H Trinh, Oguz Tuncer, Helen L Turner, Berndt Urlesberger, Klemens Vierlinger, Gabriel A Vignolle, Rutvi Vyas, Moses Wabukoma, Elena Wachtel, Benjamin Warf, Michael Woglom, Christina H Wolfsberger, Kristine Woodward, Eyyup Yurekturk","doi":"10.3233/NPM-249004","DOIUrl":"https://doi.org/10.3233/NPM-249004","url":null,"abstract":"","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":"17 3","pages":"S393-S419"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141909891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A M Da Silva, J R De Lavôr, V S Freitas, A R Vieira
{"title":"Risk of orofacial clefts in relation to maternal body mass index, diabetes and hypertension.","authors":"A M Da Silva, J R De Lavôr, V S Freitas, A R Vieira","doi":"10.3233/NPM-230118","DOIUrl":"10.3233/NPM-230118","url":null,"abstract":"<p><strong>Background: </strong>To investigate if maternal body mass index, diabetes and hypertension are associated with orofacial clefts.</p><p><strong>Methods: </strong>Case-control study. Information from 53,188 live births with and without orofacial cleft registered at USA Vital Statistics Natality Birth Data between 2017 and 2021. Case group consisted of all affected live births diagnosed with orofacial clefts (13,297 cases). Comparison group consisted of 39,891 live births without clefts or any other congenital malformation. Information about orofacial cleft cases were compared with the comparison group. The unadjusted and adjusted Odds Ratios were estimated to evaluate the strength of association between mother's pre-pregnancy body mass index, maternal diabetes and hypertension and orofacial cleft occurrence, assuming a p value < 0.05 and 95% confidence intervals (95% C.I.) for statistically significant differences.</p><p><strong>Results: </strong>Mother's pre-pregnancy body mass index, maternal diabetes and maternal hypertension are conditions associated with an increased risk of orofacial cleft development in the child (OR = 1.08, p = 0.004, 95% C.I. = 1.024-1.149; OR = 1.32, 95%, p = 0.000, 95% C.I. = 1.202-1.444; and OR = 1.35, p = 0.000, 95% C.I. = 1.239-1.484; respectively). Maternal ethnicity, sex of infant, and cigarette smoking pregnancy remained as covariates after adjustments in all logistic regression models.</p><p><strong>Conclusion: </strong>Due to the increased prevalence of obesity, diabetes, and hypertension, and also to their association with congenital malformations, such as clefts, it is recommended that mothers planning to become pregnant to follow healthy habits, maintain healthy weight, and be screened for possible diabetes or hypertension prior to conception and early in pregnancy.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":" ","pages":"41-48"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139567218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L Letzkus, M Conaway, R Daugherty, M Hook, S Zanelli
{"title":"A randomized-controlled trial of parent-administered interventions to improve short-term motor outcomes in hospitalized very low birthweight infants.","authors":"L Letzkus, M Conaway, R Daugherty, M Hook, S Zanelli","doi":"10.3233/NPM-230206","DOIUrl":"10.3233/NPM-230206","url":null,"abstract":"<p><strong>Background: </strong>Premature infants are at increased risk for cerebral palsy (CP). Early interventions with a motor focus and administered by parents may improve motor outcomes.</p><p><strong>Aims: </strong>Secondary study evaluating the short-term motor outcomes and risk for CP in very low birthweight (VLBW) infants randomized to multimodal interventions with a motor focus provided by parents versus usual care.</p><p><strong>Study design: </strong>Randomized controlled trial (intervention vs. usual care (control group)).</p><p><strong>Subjects: </strong>Infants (<32 weeks' gestational age (GA) and/or <1500 grams birthweight) born between March 2019 and October 2020.</p><p><strong>Outcome measures: </strong>Short-term motor outcomes and risk for CP was evaluated using the Hammersmith Infant Neurological Evaluation (HINE, primary motor outcome), the General Movement Assessment (GMA) and the Test of Infant Motor Performance (TIMP) at 3 months' postmenstrual age (PMA).</p><p><strong>Results: </strong>70 participants were enrolled (GA 28.3±2.7 weeks, birthweight 1139.2±376.6 grams, 64.3% male). The in-person follow-up rate was 73%, lower than expected, in part due to COVID-19 restrictions, resulting in 25 infants (intervention) and 26 infants (control) with outcome data available for analysis. There was not a significant difference in the HINE, GMA or TIMP at 3 months' PMA between groups.</p><p><strong>Conclusion: </strong>Multimodal interventions with a motor focus and provided by parents need further investigation to determine if they can improve short-term motor outcomes in VLBW infants. These interventions are evidence-based and the evaluation of broader implementation into routine care is also needed.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":" ","pages":"637-645"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142289472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Standardization of urinary tract infection diagnosis in the neonatal ICU: Experience at a tertiary care center.","authors":"B Krasity, M Hasan, S Uppuluri, P Prazad","doi":"10.3233/NPM-230101","DOIUrl":"10.3233/NPM-230101","url":null,"abstract":"<p><strong>Background: </strong>Urinary tract infections (UTIs) and antibiotic overexposure are common neonatal problems. Recently, evidence has emerged that a standardized approach to neonatal UTI can reduce unnecessary diagnosis without complications. This quality improvement project aimed to achieve those goals in our neonatal intensive care unit (NICU).</p><p><strong>Methods: </strong>A UTI diagnosis guideline was adapted from the literature with the goal of maximizing the proportion of diagnosed UTIs that conform to accepted diagnostic criteria: >10,000 CFU/mL of one organism with pyuria, or >50,000 CFU/mL of one organism regardless of pyuria. The guideline was implemented in a level III NICU. Adherence, results, and complications were monitored for 12 months.</p><p><strong>Results: </strong>Guideline adherence after implementation was favorable, as evidenced by increased adoption of urinalysis with microscopy. There was a non-significant increase in diagnostic adherence to criteria, 87% to 93%, and non-significant decrease in the rate of UTI diagnosis, 39% to 36%. Complications were not significantly changed. Most UTIs were due to gram-negative rods, especially E. coli; Enterococcus was a common contaminant.</p><p><strong>Conclusions: </strong>A guideline for diagnosing UTIs can safely increase uniformity. In contrast to previously published results, no significant changes were seen in the rate of UTI or the proportion of diagnoses conforming to the criteria for UTI. It is likely that guideline effects depend on the established practices of NICU providers. Additionally, a consistent pattern was seen in which organisms were more likely to be judged the source of true UTIs or contaminated cultures, meriting further study.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":" ","pages":"13-20"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139712416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Mansouri, K Servatyari, K Rahmani, S Sheikhahmadi, S Hemmatpour, A Eskandarifar, M Rahimzadeh
{"title":"Surfactant administration methods for premature newborns: LISA vs. INSURE comparative analysis.","authors":"M Mansouri, K Servatyari, K Rahmani, S Sheikhahmadi, S Hemmatpour, A Eskandarifar, M Rahimzadeh","doi":"10.3233/NPM-230194","DOIUrl":"10.3233/NPM-230194","url":null,"abstract":"<p><strong>Introduction: </strong>Respiratory Distress Syndrome (RDS) is the most common respiratory disorder among premature infants. The use of surfactant has significantly reduced respiratory complications and mortality. There are two conventional methods for administering surfactant: Intubate-Surfactant-Extubate (INSURE) and Less Invasive Surfactant Administration (LISA). This study aims to compare the effects of surfactant administration using these two methods on the treatment outcomes of premature newborns.</p><p><strong>Materials and methods: </strong>In this retrospective cohort study, we included 100 premature newborns with RDS and spontaneous breathing who were admitted to the Neonatal Intensive Care Unit of Besat Hospital in Sanandaj city in 2021. Exclusion criteria comprised congenital anomalies and the needing for intubation for resuscitation at birth. The outcomes of epmericaly trated with two methods were compared: the LISA (50 neonates) and the INSURE (50 neonates). Our interesting outcomes were needing for mechanical ventilation, duration of ventilation, pneumothorax, pulmonary hemorrhage, severe retinopathy, CPAP duration, and bronchopulmonary dysplasia. Finally, we entered the data into STATA-14 statistical software and analyzed it using chi-square and t-tests.</p><p><strong>Results: </strong>In this study, 69% of the neonates were boys. The LISA group exhibited significantly lower rates of need for mechanical ventilation (P = 0.003) and ventilation duration (P < 0.001) compared to the INSURE group. Conversely, there were no significant differences between the two groups (P > 0.05) in terms of pneumothorax, pulmonary hemorrhage, severe retinopathy, CPAP duration, and bronchopulmonary dysplasia rates.</p><p><strong>Conclusion: </strong>The results of this study suggest that the LISA method is a safe and non-invasive approach for surfactant administration. Notably, it resulted in a reduced need for mechanical ventilation and decreased ventilation duration compared to the INSURE method.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":"17 2","pages":"233-239"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140957918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preterm infant with necrotizing enterocolitis and arteritis secondary to streptococcus gallolyticus subspecies pasteurianus.","authors":"J A Stewart, E Culverhouse, Mathew Harrell","doi":"10.3233/NPM-230089","DOIUrl":"10.3233/NPM-230089","url":null,"abstract":"<p><p> Streptococcus gallolyticus subspecies pasteurianus is a subtype of Streptococcus bovis (S. bovis) that has become increasingly recognized as a sepsis-causing pathogen in neonates. It is well documented that S. bovis species have a predilection to both cardiac and gastrointestinal tissue, and in adult populations, isolating these organisms in the bloodstream often triggers further evaluation for co-morbid complications such as colon cancer or endocarditis. However, no such guidance currently exists in neonatal literature. We present a case of a preterm infant with S. gallolyticus subsp. pasteurianus bacteremia presenting as necrotizing enterocolitis (NEC) not previously described in the literature. Furthermore, through a complete diagnostic evaluation, including an echocardiogram, our patient was found to have the rare complication of endocarditis.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":" ","pages":"265-268"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140864354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marlen Fossan Aas, Ceyda Acun, Hany Aly, Alan Bainbridge, Claire Baldauf, Anna Basu, Marco Belzu, Ivo Bendix, Manuel Benitez, Camille Bloom, Aoife Branagan, Anne Breaks, Markus Brechmann, Amanda Brosius-Lutz, Nur Sena Cagatay, Ellie Campbell, Pelin Cengiz, Feyza Cetin, Lina Chalak, Vann Chau, Sara Cherkerzian, Rakesh Chhabra, Nancy Chorne, Luc Collo, Alexa Craig, Anya Cutler, Ilenia D'Angelo, Madison Denney, Sarah Edney, Claes Ekström, Mohamed El-Dib, Carlos Fajardo, Ursula Felderhoff-Müser, Peter Ferrazzano, Markus Gallert, Aisling Garvey, Thomas Gentinetta, Fernando Gonzalez, Robin W Goy, Magnus Gram, Gunnthorunn Gunnarsdottir, Aashish Gupta, Kirsten Guse, Valérie Haesler, Catherine Hahn, Katie HannonTaylor Harris, Karin Hermans, Ruben Hernandez, Josephine Herz, Angela Hoyos, Terrie Inder, Johana Isaza-Correa, Irem Isik, Marianne Joerger-Messerli, Sandra Juul, Brian Kalish, Amita Kapoor, Helena Karlsson, Sreenivas Karnati, Chant Katrjian, Lynne Kelly, Karina Kempe, Marwa Khalil, Yujin Kim, Clairette Kirezi, Amanda Kristiansson, Maggie Kucera, Rakesh Lavu, Nadia Leake, Jon E Levine, David Ley, Yi Li, Emily Lo, Tara Lozy, Katherine Mackenzie, George Maple, Amit Mathur, Robert McKinstry, Christopher Meehan, Jan Miletin, Eleanor J Molloy, Sissel J Moltu, Sarah Monsell, Luis Monterrosa, Juhi Motiani, Nicholas Nicoletti, Tone Nordvik, Jennifer O'Malley, Niklas Ortenlöf, Burak Ozaydin, Ana Alvarez Pagan, Raymand Pang, Lindsay Pennington, Sandra Mena Perez, Helle C Pfeiffer, Anette Ramm-Pettersen, Judith Rankin, Mandana Rizazad, Nicola Robertson, Sriya Roychaudhuri, Elizabeth Scharnetzki, Andreina Schoeberlein, Leah Marie Seften, Meray Serdar, Amr El Shahed, Ariel Sherbany, Farag Shuweihdi, Abhijeet Singla, Claudia Stanciu, Marel Steinfort, Tom Stiris, Daniel Surbek, Fransisco Torrealdea, Vera Tscherrig, Katie Tucker, Suvi Vallius, Claudine Vavasseur, Valérie Verdon, Carolina Villegas, Mari Viviers, Donna Wall, Brian H Walsh, Kay-Anja Walther, Kirstin Webster, Kristina Wendel, Martin White, Katarzyna Wiatrowska, Diane Wilson, Jessica Wisnowski, Sarah Worley, Tai-Wei Wu, Yvonne Wu, Courtney Wusthoff, Sefer Yapici
{"title":"Proceedings of the 15th International Newborn Brain Conference: Neuroprotection strategies in the neonate.","authors":"Marlen Fossan Aas, Ceyda Acun, Hany Aly, Alan Bainbridge, Claire Baldauf, Anna Basu, Marco Belzu, Ivo Bendix, Manuel Benitez, Camille Bloom, Aoife Branagan, Anne Breaks, Markus Brechmann, Amanda Brosius-Lutz, Nur Sena Cagatay, Ellie Campbell, Pelin Cengiz, Feyza Cetin, Lina Chalak, Vann Chau, Sara Cherkerzian, Rakesh Chhabra, Nancy Chorne, Luc Collo, Alexa Craig, Anya Cutler, Ilenia D'Angelo, Madison Denney, Sarah Edney, Claes Ekström, Mohamed El-Dib, Carlos Fajardo, Ursula Felderhoff-Müser, Peter Ferrazzano, Markus Gallert, Aisling Garvey, Thomas Gentinetta, Fernando Gonzalez, Robin W Goy, Magnus Gram, Gunnthorunn Gunnarsdottir, Aashish Gupta, Kirsten Guse, Valérie Haesler, Catherine Hahn, Katie HannonTaylor Harris, Karin Hermans, Ruben Hernandez, Josephine Herz, Angela Hoyos, Terrie Inder, Johana Isaza-Correa, Irem Isik, Marianne Joerger-Messerli, Sandra Juul, Brian Kalish, Amita Kapoor, Helena Karlsson, Sreenivas Karnati, Chant Katrjian, Lynne Kelly, Karina Kempe, Marwa Khalil, Yujin Kim, Clairette Kirezi, Amanda Kristiansson, Maggie Kucera, Rakesh Lavu, Nadia Leake, Jon E Levine, David Ley, Yi Li, Emily Lo, Tara Lozy, Katherine Mackenzie, George Maple, Amit Mathur, Robert McKinstry, Christopher Meehan, Jan Miletin, Eleanor J Molloy, Sissel J Moltu, Sarah Monsell, Luis Monterrosa, Juhi Motiani, Nicholas Nicoletti, Tone Nordvik, Jennifer O'Malley, Niklas Ortenlöf, Burak Ozaydin, Ana Alvarez Pagan, Raymand Pang, Lindsay Pennington, Sandra Mena Perez, Helle C Pfeiffer, Anette Ramm-Pettersen, Judith Rankin, Mandana Rizazad, Nicola Robertson, Sriya Roychaudhuri, Elizabeth Scharnetzki, Andreina Schoeberlein, Leah Marie Seften, Meray Serdar, Amr El Shahed, Ariel Sherbany, Farag Shuweihdi, Abhijeet Singla, Claudia Stanciu, Marel Steinfort, Tom Stiris, Daniel Surbek, Fransisco Torrealdea, Vera Tscherrig, Katie Tucker, Suvi Vallius, Claudine Vavasseur, Valérie Verdon, Carolina Villegas, Mari Viviers, Donna Wall, Brian H Walsh, Kay-Anja Walther, Kirstin Webster, Kristina Wendel, Martin White, Katarzyna Wiatrowska, Diane Wilson, Jessica Wisnowski, Sarah Worley, Tai-Wei Wu, Yvonne Wu, Courtney Wusthoff, Sefer Yapici","doi":"10.3233/NPM-249002","DOIUrl":"https://doi.org/10.3233/NPM-249002","url":null,"abstract":"","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":"17 3","pages":"S317-S344"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141909890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B R Hadfield, T Sawyer, A G Moreira, R Farner, M M Vasquez
{"title":"Rapid cycle deliberate practice improves resident performance during ELBW resuscitation.","authors":"B R Hadfield, T Sawyer, A G Moreira, R Farner, M M Vasquez","doi":"10.3233/NPM-230102","DOIUrl":"10.3233/NPM-230102","url":null,"abstract":"<p><strong>Background: </strong>Neonatal Resuscitation is a required competency for pediatric and family medicine residency programs. Simulation-based training can be used to supplement clinical experience. Rapid Cycle Deliberate Practice (RCDP) has been validated as an effective education model and is gaining favor over traditional simulation models. The aim of this study was to evaluate the effectiveness of a simulation-based rapid cycle deliberate practice (RCDP) intervention on extremely low birth weight (ELBW) infant resuscitation.</p><p><strong>Methods: </strong>Pediatric and family practice residents were randomized to control and intervention groups and participated in pre- and post-NICU rotation simulations. The intervention group received one RCDP session. Simulations were scored by blinded video review for overall performance, positive pressure ventilation (PPV), endotracheal intubation and behavioral skills. Surveys assessed confidence in ELBW resuscitation.</p><p><strong>Results: </strong>Forty-one residents participated in the study. The RCDP group performed better than the control group at post-rotation evaluation for overall resuscitation performance (65% vs 87%, p = 0.004), administering PPV (63% vs 88%, p = 0.006), and validated behavior skills (1.4 vs 2.0, p = 0.019). Residents in the RCDP group reported greater confidence with ELBW resuscitation.</p><p><strong>Conclusion: </strong>An educational intervention using RCDP was associated with improved resident performance and confidence in ELBW resuscitation. RCDP should be considered for NRP and ELBW resuscitation training.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":" ","pages":"31-40"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139465691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"External biliary drainage before choledochal cyst treatment in a very low birth weight infant.","authors":"Ting-Yu Lee, C-W Chen","doi":"10.3233/NPM-230067","DOIUrl":"10.3233/NPM-230067","url":null,"abstract":"<p><p>Choledochal cysts (CC) are congenital biliary tract dilatations. Infantile CC (IFCC) in very low birth weight (VLBW) infants is rare. This is a case of a huge IFCC presented in VLBW preterm infant managed with external biliary drainage prior to definitive treatment. Electrolyte imbalance, poor weight gain, and infections were managed during external biliary drainage maintenance. Choledochal cyst excision and Roux-en-Y hepaticoenterostomy were successfully performed when the infant weighed 4.9 kg 5 months later. Delayed definitive treatment with external biliary drainage could be a feasible alternative for managing CC in low-birth-weight infants.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":" ","pages":"133-136"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139567214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}