Journal of Neuro-Ophthalmology最新文献

{"title":"Neuro-Ophthalmology Meets Vision Rehabilitation-A Festschrift in Tübingen Honoring Susanne Trauzettel-Klosinski.","authors":"Klara Landau, Jonathan C Horton, Kathleen Digre","doi":"10.1097/WNO.0000000000002509","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002509","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148549241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bilateral Ischemic Optic Neuropathy in a Patient With 3243 A > G Mutation.","authors":"Celia Ruiz-Arranz, José Alberto Reche-Sainz, María Del Carmen Sánchez-Sánchez, Teresa García, Montserrat Morales","doi":"10.1097/WNO.0000000000002500","DOIUrl":"10.1097/WNO.0000000000002500","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148456137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aspergillus-Infiltrated Optic Nerve Sheath Meningioma in Immunocompetent Host Mimicking Optic Neuritis.","authors":"Haoran C Li, David G Munoz, Suradech Suthiphosuwan, Jonathan A Micieli","doi":"10.1097/WNO.0000000000002489","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002489","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148308457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Progression of Vitreous Detachment Leading to Exacerbation of Visual Field Loss in Acute Nonarteritic Anterior Ischemic Optic Neuropathy.","authors":"Hugo Wu, Anas Alkhabaz, Fannie Nadeau, Yaping Joyce Liao","doi":"10.1097/WNO.0000000000002488","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002488","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148264751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optic Disc Drusen Is Frequently Not Reported on Computed Tomography Scans Performed for Other Reasons.","authors":"Sara KamaliZonouzi, Jonathan A Micieli","doi":"10.1097/WNO.0000000000002494","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002494","url":null,"abstract":"<p><strong>Background: </strong>Optic disc drusen (ODD), which can mimic papilledema and pose a diagnostic challenge to ophthalmologists, can be effectively detected using computed tomography (CT). In this retrospective study, we investigated how often radiologists report the presence of drusen on CT scans when the indication may not have been ODD.</p><p><strong>Methods: </strong>This was a retrospective chart review of consecutive patients with ODD with previous brain CT scan performed for various unrelated reasons. The inclusion criteria included patients with fundus autofluorescence, or optical coherence tomography-enhanced depth imaging-proven ODD who already had CT scan done for any reason.</p><p><strong>Results: </strong>Twenty-five CT scan reports from 23 patients (43 eyes; 17 women, 6 men) were included, with a mean age of 37.0 ± 19.2 years (range, 10-74). ODD were bilateral in 20 patients (87.0%) and unilateral in 3 (13.0%). Five CT scans were performed with contrast (20.0%) and 20 without contrast (80.0%). ODD were explicitly mentioned in only 8 of 25 reports (32.0%), despite being present in all patients. It was mentioned in all 5 scans performed for unrelated neuro-ophthalmic indications.</p><p><strong>Conclusions: </strong>In conclusion, ODD were underreported on CT scans, with only 32% of reports explicitly mentioning their presence. This has implications for radiologists, who should be aware of the importance of ODD to ophthalmologists, who may look back at previous CT scans. Ophthalmologists should be aware that the absence of an ODD mention in a CT report does not indicate the absence of ODD on the imaging.</p>","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148258502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterizing the Role of Ophthalmologists in the Care of Patients With Suspected Giant Cell Arteritis at an Academic Medical Center.","authors":"Katherine G O'Neill, Randall J Brown, Heather E Moss","doi":"10.1097/WNO.0000000000002485","DOIUrl":"10.1097/WNO.0000000000002485","url":null,"abstract":"<p><strong>Background: </strong>Evaluation and treatment of giant cell arteritis (GCA) is multidisciplinary, with high morbidity if not promptly treated. Ophthalmologists may be involved due to the presence of visual symptoms and/or ischemic vision loss. The goal of this study was to characterize the health care journey of patients suspected of having GCA and elucidate the role that ophthalmologists and other specialists play in their prebiopsy evaluation.</p><p><strong>Methods: </strong>This retrospective study included patients at a single large academic institution who underwent a temporal artery biopsy (TAB) as part of a GCA evaluation over a 10-year period. Demographics, symptoms, laboratory testing, ancillary imaging, treatment initiation, biopsy results, and final diagnosis were extracted from the medical record. Types of specialists involved in different aspects of the prebiopsy evaluation for GCA were tabulated. A Sankey plot was created to visualize the included patients' journeys.</p><p><strong>Results: </strong>Among 162 subjects undergoing TAB (average age of 74 years SD 11.3, 64.8% female, 60% ocular symptoms), 43 were diagnosed with GCA (30 positive TAB). Subjects saw an average of 3.31 providers (SD 1.15) from different specialties during their prebiopsy evaluation, with multiple patients seeing 6 different specialists. Within our cohort, 51% (n = 83) of patients saw ophthalmologists before TAB and 33% (n = 53) had their TAB performed by an ophthalmologist. Seeing an ophthalmologist during the prebiopsy period was not associated with a positive biopsy result (P = 0.80) or prebiopsy steroid treatment for GCA (P = 0.90).</p><p><strong>Conclusions: </strong>GCA suspects have a convoluted journey through our health care system and are commonly seen by multiple medical subspecialists during their evaluation. This may benefit patients due to multiple expert perspectives or may contribute to fragmentation of care and delays in treatment. These results reinforce the number of subspecialists, including ophthalmologists, who play a role in the evaluation of GCA. Multidisciplinary fast-track GCA clinics can both provide access to subspeciality care and simplify the patient journey.</p>","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13406389/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148258395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Noninvasive Estimation of Intracranial Pressure Using Optic-Disc Venous Pulsation Thresholds.","authors":"Thomas J Berdahl, Brian M Shafer, John P Berdahl, Andrew G Lee, Mario I Zamora, Daniel C Terveen","doi":"10.1097/WNO.0000000000002487","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002487","url":null,"abstract":"<p><strong>Background: </strong>Pulsations and pressure changes in the retinal vein are known to be implicated in glaucoma and are sensitive to changes in both intraocular and intracranial pressures (IOP and ICP). This study evaluates the feasibility and physiological concordance of estimating ICP from spontaneous retinal venous pulsation (SVP) thresholds using noninvasive negative-pressure (NP) goggles and comparing these estimates with reference ICPs measured through manometry during lumbar puncture (LP).</p><p><strong>Methods: </strong>This prospective, single-center pilot study evaluated the capacity of the Ocular Pressure Adjusting Pump (OPAP) to aid in estimating ICP. Adults who were scheduled for clinically indicated LP underwent noninvasive IOP modulation with sealed negative-pressure goggles (OPAP) within 24 hours before LP. An increasing magnitude of NP was applied until SVP was extinguished. Masked examiners determined IOP at the last presence of SVP and first absence of SVP at the optic disc, as measured through the OPAP goggles. Predicted ICP was defined as the midpoint between those 2 IOP values. OPAP measurements were performed twice for each eye: once in an upright seated position and again in the left lateral decubitus (LLD) position. Agreements between OPAP-predicted and LP-measured ICPs were evaluated with a Bland-Altman analysis using 80% limits of agreement (LoA).</p><p><strong>Results: </strong>Of 15 participants, 11 had visible SVPs that could be extinguished during NP application with OPAP and were included in the analysis. Four participants did not exhibit SVPs at baseline; all had LP-measured ICP exceeding IOP (mean ± SD: 17.6 ± 5.3 and 13.5 ± 1.1 mm Hg, respectively; P < 0.001). For eyes with measurable SVP thresholds, the mean OPAP-predicted ICP was 12.7 ± 3.2 mm Hg in an upright seated position and 17.5 ± 3.1 mm Hg in a lateral position. In the upright analysis, mean bias (predicted-reference ICP) was -0.17 mm Hg with 80% LoA ±6.19 Hg. In the lateral analysis, mean bias was +4.66 mm Hg with 80% LoA ±3.56 mm Hg.</p><p><strong>Conclusions: </strong>In this pilot feasibility study, SVP-threshold-derived ICP estimates demonstrated minimal bias when OPAP measurements were taken with patients in an upright position and systematic overestimation when OPAP measurements were taken with patients in the LLD position. Conversely, OPAP's ICP estimations demonstrated better consistency (narrower 80% LoAs) with measurements taken in the LLD as compared with upright measurements (wider 80% LoAs). These pilot study findings are exploratory in nature and are not intended to guide individual patient care. Larger studies with standardized positioning and contemporaneous reference measurements are required to define accuracy, identify sources of bias, and demonstrate clinical utility.</p>","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148258477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Compressive Optic Neuropathy Secondary to Metastatic Neuroblastoma.","authors":"Khizar H Rana, Abdullah I Almater, James A Slattery, Dinesh Selva","doi":"10.1097/WNO.0000000000002476","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002476","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148251960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When Tears Stop Flowing: A Unilateral Dry Eye in a 35-Year-Old Man.","authors":"Amandine Gauderon, Tim Beltraminelli, Vincent Dunet, Aki Kawasaki","doi":"10.1097/WNO.0000000000002491","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002491","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148176103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Horizontal Reversal of Vision Metamorphopsia Caused by Cerebellar Glioma.","authors":"Ema V Karakoleva, Chloe Shields, R Clayton Bishop, Shreya Bhatt, Ali A Firozvi, Jake Sanford, Vishal Jain, Ejaz A Shamim","doi":"10.1097/WNO.0000000000002392","DOIUrl":"10.1097/WNO.0000000000002392","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":"e38-e40"},"PeriodicalIF":2.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144789382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}