Mohammad Ahmad Alenezi, Nasir Ahmed Ali, Abdalaziz Samran Alanzi, Zaid Mohammad Alqahtani, Ashwaq Aiyad Alshammari, Refah Alsubaie, Meshari Sulaiman Bin Huwaymil, Aloush Alotaibi, Ashwaq Mohammad Alrashidi, Muna Mutlaq Alshammari, Tahreer Mutlaq Alshammari, Abdulaziz Ibrahim Ltammami
{"title":"Knowledge, practice, and attitudes regarding breast cancer self-examination among women of reproductive age in Saudi Arabia: a community-based study.","authors":"Mohammad Ahmad Alenezi, Nasir Ahmed Ali, Abdalaziz Samran Alanzi, Zaid Mohammad Alqahtani, Ashwaq Aiyad Alshammari, Refah Alsubaie, Meshari Sulaiman Bin Huwaymil, Aloush Alotaibi, Ashwaq Mohammad Alrashidi, Muna Mutlaq Alshammari, Tahreer Mutlaq Alshammari, Abdulaziz Ibrahim Ltammami","doi":"10.25122/jml-2024-0357","DOIUrl":"10.25122/jml-2024-0357","url":null,"abstract":"<p><p>Breast cancer is the second most common cancer among females worldwide and can often be detected at an early stage through breast self-examination (BSE). However, in many developing countries, most cases are diagnosed at advanced stages. This study aimed to assess the knowledge and practice of BSE among women of reproductive age in Saudi Arabia. This study adopted a community-based descriptive-analytical cross-sectional design. A stratified simple random sampling technique was used, with 50 participants from each region. Almost 500 Saudi women who fulfilled the inclusion criteria were enrolled in this study, and of these, 32.8% were within the age group of 20-29, 30.4% were within the age group of 30-39, and 32.8% were within the age group of more than 40 years. The overall knowledge score regarding BSE items among participants was 38%. Significant associations were found between breast cancer knowledge scores and demographic factors such as age group, educational level, marital status, region, and residence area (<i>P</i> < 0.05). Regarding knowledge of breast cancer risk factors, 48% of participants demonstrated poor knowledge, 43% had moderate knowledge, and only 9% had good knowledge. Effective prevention of breast cancer requires awareness and understanding of its risk factors. It is important for young women, starting from puberty, to be educated about potential changes in breast tissue and to receive proper training in BSE techniques from healthcare professionals.</p>","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"17 12","pages":"1042-1048"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11771828/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143059706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rajab Alzahrani, Wafaa Taishan, Mujtaba Ali, Alshaik Tarek, Alahmadi Khalid, Abdulrahman Almaymoni, Renad Alshehri, Lamyaa Almathahibi, Ahmed Khuzayyim, Ibrahim Al Suliman, Mohammed Alabbadi, Dalal Alghamdi
{"title":"Knowledge and attitudes of health science students and medical interns at al Al-Baha University towards epistaxis first aid.","authors":"Rajab Alzahrani, Wafaa Taishan, Mujtaba Ali, Alshaik Tarek, Alahmadi Khalid, Abdulrahman Almaymoni, Renad Alshehri, Lamyaa Almathahibi, Ahmed Khuzayyim, Ibrahim Al Suliman, Mohammed Alabbadi, Dalal Alghamdi","doi":"10.25122/jml-2024-0218","DOIUrl":"10.25122/jml-2024-0218","url":null,"abstract":"<p><p>Epistaxis, or nosebleeds, is a common medical concern in emergency departments worldwide, often triggered by trauma, infections, allergies, and high blood pressure. Despite its frequency, there is limited research on the knowledge and attitudes of health-related students regarding the first aid management of epistaxis. This study aimed to assess the knowledge and attitudes toward first aid management of epistaxis among health-related specialty students at Al-Baha University, Saudi Arabia. A cross-sectional study was conducted using a self-administered online questionnaire. A total of 370 participants were recruited through convenience sampling. Data were analyzed using descriptive statistics and chi-square tests to identify significant associations. The findings revealed that over 70% of participants showed strong knowledge in identifying causes of epistaxis and applying first aid, although only 9.6% correctly differentiated between various causes of nosebleeds. Attitudes were highly positive, with 92.1% of respondents supporting training in nosebleed first aid and 85.9% recognizing epistaxis as a health priority. Significant differences in knowledge scores were observed based on age, academic year, and previous training (<i>P</i> < 0.05). Participants reported a median self-assessed confidence and knowledge rating of 6 on a 10-point scale. These findings underscore the need for targeted education and training in nosebleed management among healthcare students. The study highlights the need to address knowledge gaps and improve attitudes towards epistaxis first aid management among health-related specialty students at Al-Baha University in Saudi Arabia.</p>","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"17 12","pages":"1082-1087"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11771830/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143059628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The role of dentate status and dental caries on diabetes-related complications: a hospital-based cross-sectional study.","authors":"Sunithi Thearawiboon, Chanapong Rojanaworarit","doi":"10.25122/jml-2024-0405","DOIUrl":"10.25122/jml-2024-0405","url":null,"abstract":"<p><p>This study explored the role of dentate status and dental caries on diabetes-related complications among patients with type 2 diabetes mellitus (T2DM). A hospital-based cross-sectional design was applied to collect data on diabetic patients attending integrated services for non-communicable diseases and oral health at a public hospital in Thailand. Diabetic complication outcomes included diabetic eye and foot complications and chronic kidney disease (CKD). The main independent variable of dentate status and dental caries was classified into three categories: dentate and caries-free, dentate with caries, and edentulous. The relationships were evaluated through epidemiological models depicted by directed acyclic graphs (DAGs). Multivariable Poisson regression with robust standard errors was applied to estimate prevalence ratios (PR) according to DAGs. Among 438 patients with T2DM, 62.8% were women, and an average age was 63.6 years. Most patients were dentate with dental caries (70.1%), and 8.2% were edentulous. Prevalence of diabetic foot complications and CKD were 37.1% and 10.1%. Six patients had eye complications. Regarding CKD outcome, PR estimates from univariable and multivariable models were 0.94-1.12 for the dentate with caries group and 1.67-2.31 for the edentulous group, all with non-significant <i>P</i> values. Regarding foot complication outcome, PR estimates were 1.10-1.12 for the dentate with caries group and 1.26-1.37 for the edentulous group, all with non-significant <i>P</i> values. Though not statistically significant, the magnitude and direction of PR suggested a possible hypothesis that, among patients with T2DM, edentulism might be related to a higher prevalence of CKD and diabetic foot complications as compared to being dentate and caries-free.</p>","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"17 12","pages":"1072-1081"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11771835/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143059174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Housam Almadani, Malik Almailabi, Marwan Henaidi, Mohammed Almelibari, Yazeed Almhgadi, Hawazeni Alsulaimani, Moayed Almanabri
{"title":"Barriers facing emergency physicians in providing urgent care to pediatric patients in Saudi Arabia - a cross-sectional study.","authors":"Housam Almadani, Malik Almailabi, Marwan Henaidi, Mohammed Almelibari, Yazeed Almhgadi, Hawazeni Alsulaimani, Moayed Almanabri","doi":"10.25122/jml-2024-0291","DOIUrl":"10.25122/jml-2024-0291","url":null,"abstract":"<p><p>Efforts to improve healthcare services have been ongoing, particularly in equipping emergency departments (EDs) to handle pediatric cases. However, many EDs continue to lack specialized equipment and adequately trained personnel, exposing children to significant health risks. This study aimed to identify self-reported barriers among emergency physicians in managing pediatric patients and assess their confidence levels in pediatric care. A cross-sectional survey was conducted between March 2023 and January 2024 among emergency physicians dealing with pediatric emergencies practicing in the Kingdom of Saudi Arabia. Data were collected through an online self-administered questionnaire, which included demographic details, perceived barriers in pediatric care, availability of pediatric services, recommendations for improvement, and a 4-item confidence assessment. Out of 214 ED physicians, 197 responded (response rate: 92.1%), with junior residents comprising 40.1% of participants. The most reported barriers were determining accurate medication doses (20.8%) and managing interactions with parents (19.8%). Confidence in pediatric care was reported by 46.2% of participants and was significantly higher among consultants (AOR = 2.522; 95% CI, 1.187-5.358; <i>P</i> = 0.016) and those who encountered pediatric patients regularly during their shifts (AOR = 3.113; 95% CI, 1.396-6.946; <i>P</i> = 0.006). Conversely, lower confidence was observed among physicians who recommended workshops and mandatory training courses for improving pediatric care quality (AOR = 0.475; 95% CI, 0.228-0.988; <i>P</i> = 0.046). The findings highlight a lack of confidence among ED physicians in managing pediatric patients, with confidence levels varying based on the age of patients and frequency of pediatric exposure. The most common challenges were accurate medication dosing, interactions with parents, and addressing a diverse range of pediatric diseases. Consultants and regular exposure to pediatric cases were associated with increased confidence, while a perceived need for workshops and mandatory courses predicted decreased confidence.</p>","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"17 12","pages":"1054-1060"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11771831/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143059582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mortality predictors in acute myocardial infarction: results from a single-center study in Saudi Arabia.","authors":"Yasir Abdulmohsen Alzalabani, Bader Osama Sager, Hamzah Khalid Ibrahim, Faisal Mohammed Alnami, Yazeed Mosa Alharbi, Ammar Khalid Almatrafi, Ayat Roushdy","doi":"10.25122/jml-2024-0366","DOIUrl":"https://doi.org/10.25122/jml-2024-0366","url":null,"abstract":"<p><p>Acute myocardial infarction (AMI) is a leading cause of morbidity and mortality worldwide. Risk factors of mortality in patients with AMI have been widely investigated, identifying older age and heart failure as common contributors. This study aimed to determine risk factors and explore predictors associated with higher mortality among patients with AMI. A retrospective study was conducted at a cardiac center in western Saudi Arabia (KSA) between January 1, 2023, and September 1, 2023. Inclusion criteria comprised patients with a confirmed diagnosis of AMI. Exclusion criteria included patients younger than 18 and those with incomplete diagnostic or follow-up data. A data collection form was generated, including all possible factors associated with mortality among patients with AMI. The study included 851 MI patients with a mean age of 58.78 years, primarily male participants. Survival analysis based on the days of hospitalization revealed that 30-day and 60-day survival rates post-hospitalization were 66.8% and 33.4%, respectively. Patients with acute MI of the anterior wall or other specific sites demonstrated significantly higher risks of mortality compared to those with unspecified acute MI. Elevated creatine kinase-myocardial band (CK-MB) levels and blood urea nitrogen (BUN) were also significantly associated with increased mortality risk. The findings highlighted an association between mortality and diabetes mellitus (DM) and transmural MI of the anterior wall. Significant differences between surviving and deceased patients were observed in several factors, including troponin, CK-MB, low-density lipoprotein (LDL), BUN, creatinine levels, age, and hospital stay duration.</p>","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"17 11","pages":"1000-1006"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11705476/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recurrence of chronic lymphatic leukemia as infiltration of the spinal cord.","authors":"Josef Finsterer, Victor Rathkolb","doi":"10.25122/jml-2024-0321","DOIUrl":"https://doi.org/10.25122/jml-2024-0321","url":null,"abstract":"<p><p>Central nervous system (CNS) involvement in chronic lymphocytic leukemia (CLL) is rare, and spinal cord infiltration as a presenting manifestation has only rarely been described. We present the case of a 65-year-old man with CLL, initially diagnosed at the age of 54, who had not received prior treatment. He presented with a six-week history of thoracic and epigastric pressure. Mild ataxia was found in the clinical exam. Clinical evaluation revealed leukocytosis (163 G/L; normal range: 4-10 G/L). MRI of the spine showed a mildly enhancing, T2 hyperintense central lesion extending between C3 and T8. There was a pleocytosis of 105 /micro/l consisting of neoplastic B-lymphocytes. The bone marrow biopsy diagnosed a relapse of CLL, and the patient was started on ibrutinib, which had a positive effect. This case highlights spinal cord infiltration as a rare initial manifestation of CLL relapse, presenting with non-specific symptoms such as thoracic and epigastric pressure and mild spinal ataxia.</p>","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"17 11","pages":"1020-1022"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11705477/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optical tweezers in biomedical research - progress and techniques.","authors":"Dharm Singh Yadav, Tudor Savopol","doi":"10.25122/jml-2024-0316","DOIUrl":"https://doi.org/10.25122/jml-2024-0316","url":null,"abstract":"<p><p>Optical tweezers, which leverage the forces exerted by radiation pressure, have emerged as a pivotal technique for precisely manipulating and analyzing microscopic particles. Since Arthur Ashkin's ground-breaking work in the 1970s and the subsequent development of the single-beam optical trap in 1986, the capabilities of optical tweezers have expanded significantly, enabling the intricate manipulation of biological specimens at the micro- and nanoscale. This review elucidates the foundational principles of optical trapping and their extensive applications in the biomedical sciences. The applications of optical tweezers in biomedicine are vast, ranging from the investigation of cellular mechanical properties, such as cell stretching, membrane elasticity, and stiffness, to single-molecule studies encompassing DNA and protein mechanics, protein-DNA interactions, molecular motor functions, and pathogen-host interactions. Advancement of optical tweezers in this field includes their integration with holography, fluorescence microscopy, microfluidics, and enhancements in force sensitivity and positional accuracy. These tools have profoundly impacted the study of cellular mechanics, drug discovery processes, and disease diagnostics, providing unparalleled insights into the biophysical mechanisms underlying health and pathology.</p>","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"17 11","pages":"978-993"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11705474/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Knosp and revised Knosp classifications predict non-functioning pituitary adenoma outcomes: a single tertiary center experience.","authors":"Siham Rouf, Soumiya Berrabeh, Lamiae Zarraa, Hanane Latrech","doi":"10.25122/jml-2024-0015","DOIUrl":"https://doi.org/10.25122/jml-2024-0015","url":null,"abstract":"<p><p>Non-functioning pituitary adenomas (NFPAs) are hormonally inactive benign tumors, usually diagnosed as macro-adenoma. The aim of our research was to analyze the clinical and hormonal characteristics of NFPAs using Knosp and revised Knosp classifications. Furthermore, we aimed to assess the possibility of predicting surgical remission after surgery. This was a prospective descriptive-analytical study. We selected 30 patients with non-functioning pituitary adenomas by excluding all the clinical and biochemical evidence of hormone excess. Cavernous sinus invasion was evaluated by Knosp and revised Knosp classifications. The mean age was 50.8 ± 11.6 years, and 63.3% of the patients were women with a sex ratio F/M of 1.7. Patients with a Knosp grade greater than two experienced more symptoms, such as headaches (<i>P</i> = 0.014) and declining visual acuity (<i>P</i> = 0.095). Additionally, these patients were found to have a higher prevalence of growth hormone deficiency compared to those with a Knosp grade of two or lower (<i>P</i> = 0.037). The revised Knosp classification showed no significant difference between patients with invasive adenomas (grade ≥ 3B) and patients with non-invasive adenomas (grade ≤ 3A) regarding clinical and hormonal status. However, we noticed that patients with non-invasive adenomas (grade ≤ 3A) had significant surgical remission (<i>P</i> = 0.008). A preoperative description of cavernous sinus invasion in NFPAs provided by the Knosp and revised Knosp classifications is mandatory. Our report shows that the revised Knosp classification is superior in predicting surgical remission than the Knosp classification, with no significant difference in evaluating the clinical and hormonal status between the two classifications.</p>","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"17 11","pages":"1007-1011"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11705471/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Omar Al-Nozha, Ahmed Abulkhair, Amal Hawsawi, Sawsan Sayed, Khlood Alrowathi, Nawaf Aldeeb, Hadel Alghabban, Ghaidaa Elmehallawy, Dalya Iskandarani, Mohammed Lhmdi, Inass Taha
{"title":"Impact of statin use on COVID-19 outcomes in hospitalized patients in Saudi Arabia: a retrospective cohort study.","authors":"Omar Al-Nozha, Ahmed Abulkhair, Amal Hawsawi, Sawsan Sayed, Khlood Alrowathi, Nawaf Aldeeb, Hadel Alghabban, Ghaidaa Elmehallawy, Dalya Iskandarani, Mohammed Lhmdi, Inass Taha","doi":"10.25122/jml-2024-0371","DOIUrl":"https://doi.org/10.25122/jml-2024-0371","url":null,"abstract":"<p><p>There is an increasing requirement for new therapeutic approaches to address lung inflammation caused by COVID-19. Recent evidence suggests that statins may reduce mortality in patients with respiratory infections. This study aimed to investigate the impact of statin use on COVID-19 outcomes among hospitalized patients at Ohud Hospital and King Salman Medical City (KSMC) in Madinah, Saudi Arabia. A retrospective cohort study was conducted, including 547 patients with confirmed COVID-19 diagnoses admitted between March 2020 and December 2022. Patients were classified into statin and non-statin users based on statin administration during hospitalization. Logistic regression analyses-including univariate, multivariate, and predictive stepwise models-were employed to assess associations between statin use and clinical factors. Among the 547 patients, 200 (36.5%) were prescribed statins upon admission. Statin users were predominantly men and older. The presence of low-density lipoprotein (LDL) levels ≥ 100 mg/dL, cardiovascular disease (CVD), and advanced age were identified as strong predictors of statin use, with odds ratios (ORs) of 11.1, 3.8, and 3.1, respectively. Furthermore, the odds of receiving statins were significantly higher in male patients, individuals with hypertension, those with HbA1c levels ≥ 8%, and patients with positive cultures and sensitivity results. Statin use was associated with an 18%% reduction in the risk of mortality, with an adjusted OR of 0.80 (95% CI, 0.30-2.32), and a 7% reduction in the risk of hospital stay > 10 days, although these findings did not reach statistical significance. Among patients with COVID-19, LDL ≥ 100 mg/dl, CVD, and patients older than 60 years were identified as strong predictors for statin prescription.</p>","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"17 11","pages":"994-999"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11705472/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Potential challenges to harmonize post-stroke cognitive assessment and its prognostic value: a narrative review.","authors":"Margarita Alexandrova","doi":"10.25122/jml-2024-0284","DOIUrl":"10.25122/jml-2024-0284","url":null,"abstract":"<p><p>With advances in scientific and clinical knowledge, stroke has evolved from a major cause of death to a chronic condition affecting the daily lives of sufferers, their relatives, and society. Post-stroke cognitive impairment (PSCI) is common even among individuals with good neurological recovery. When deciding on interventions aimed to improve the life quality of post-stroke patients, identifying those at high risk of cognitive decline proves crucial. Given the complexity of PSCI assessment, this narrative review discusses the feasibility of developing standardized criteria for selecting cognitive instruments. Potential approaches for establishing harmonized procedures for post-stroke cognitive assessment are presented depending on how the cognitive impairment is defined, the cognitive domains examined, the methods used to generalize cognitive data by components/domains, and their normalization against standardized normative samples. The prognostic value of cognitive assessment to identify patients at high risk of PSCI, functional dependence, and poor survival is also discussed. Implementing harmonized criteria for assessing the cognitive status of stroke patients could reduce the now considerable heterogeneity between studies and serve as a reliable basis for determining the prevalence and predicting the occurrence/aggravation of PSCI.</p>","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"17 11","pages":"963-977"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11705473/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}