{"title":"Colorectal Polyps in Young Patients Undergoing Colonoscopy.","authors":"Yuvaraj Bhusal, Bhupendra Kumar Basnet, Ramila Shrestha, Mukesh Sharma Poudel, Ajit Khanal, Nandu Silwal Poudyal, Manoj Kumar Shah, Dibas Khadka, Surendra Bhusal","doi":"10.33314/jnhrc.v22i04.5325","DOIUrl":"10.33314/jnhrc.v22i04.5325","url":null,"abstract":"<p><strong>Background: </strong>More than 10 % of colorectal carcinoma occur in patients less than 50 years. Progression of a colorectal polyp to carcinoma may take 5 to 20 years. Implementing screening guidelines and removing such polyps would reduce the progression into carcinoma. The aim of the study was to find the prevalence, distribution and histological analysis of polyps in patients under 50 years undergoing colonoscopy.</p><p><strong>Methods: </strong>Single-center cross-sectional study of 254 consecutive patients less than 50 years who underwent colonoscopy were included in the study. Patients with prior diagnosis of inflammatory bowel disease, colonic polyp(s) or colorectal carcinoma were excluded. Basic demographic data (age, gender), history of smoking and alcohol consumption were recorded. Prevalence of polyps, their location, size and histological type were estimated. Categorical data were expressed as frequencies and percentages.</p><p><strong>Results: </strong>Among 254 patients who underwent colonoscopy, 63 had colorectal polyps. 39 (61.9 %) patients with polyp were males and 33 (52.38 %) patients were of 40-49 years age. Recto-sigmoid polyps were seen in 47 (74.6 %) patients. Regular heavy alcohol consumers and active smokers had higher odds of having polyps. Adenomatous polyps and adenocarcinoma were detected in 12 and 10 patients respectively. Ulcerated or excavated appearance strongly suggested carcinomatous histology (OR: 363.8, (CI: 16.04 - 8250.90). Similarly, polyp size 5 mm or more favored adenomatous polyp or carcinoma [(OR: 177.35, CI: 9.7 - 3229)].</p><p><strong>Conclusions: </strong>Prevalence of polyps in patients below 50 years age was 24.8 %. Most of the polyps were benign, diminutive (< 5 mm) and located in recto-sigmoid colon. One-third of the polyps were adenoma or adenocarcinoma.</p>","PeriodicalId":16380,"journal":{"name":"Journal of Nepal Health Research Council","volume":"22 4","pages":"720-724"},"PeriodicalIF":0.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143648227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bhadra Hamal, Mahesh Karmacharya, Sijan Bhattachan, Pawan Kumar Hamal
{"title":"Functional Outcome of Single-Stage Reconstruction for the Multi-Ligament Injuries of the Knee.","authors":"Bhadra Hamal, Mahesh Karmacharya, Sijan Bhattachan, Pawan Kumar Hamal","doi":"10.33314/jnhrc.v22i04.5472","DOIUrl":"10.33314/jnhrc.v22i04.5472","url":null,"abstract":"<p><strong>Background: </strong>Multi-ligament injuries of the knee are rare injuries that can cause significant impairment of the knee function. There is controversy in the treatment regarding staged versus single-stage surgery. This study was performed to assess the outcome of the single-staged reconstruction of the multi-ligament injury of the knee.</p><p><strong>Methods: </strong>This prospective observational study was done from January 15, 2022 to January 14, 2023. The outcome was analyzed by comparing the preoperative and 12-month postoperative Visual Analog Scale score, Lysholm Score, and International Knee Documentation Committee Score.</p><p><strong>Results: </strong>The mean age of the patients was 28.35 years. among 12 patients 9 were male and 3 were female. Single-staged multi-ligament reconstruction was done in all the cases. The Lysholm score was improved from preoperatively 36.42 ± 1.46 to 95.36 ± 2.84, IKDC score was improved from 24.38 ± 1.64 to 93.86 ± 3.14, VAS score 8.14 ± 1.44 to 0.40 ± 0.60 at 12 months postoperative follow-up which all came to be clinically significant with p-value < 0.001.</p><p><strong>Conclusions: </strong>Single-stage multi-ligament reconstruction of the knee is an effective method of treatment and has excellent outcomes.</p>","PeriodicalId":16380,"journal":{"name":"Journal of Nepal Health Research Council","volume":"22 4","pages":"751-755"},"PeriodicalIF":0.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jaya Laxmi Pradhan, Pooja Devkota, Sita Kumari Sen, Nirmala Bhatta
{"title":"Effects of Nutritional Counselling on Dietary Intake and Nutritional Status of Pregnant Women Attending Health Facilities In Dang Province 5 Nepal.","authors":"Jaya Laxmi Pradhan, Pooja Devkota, Sita Kumari Sen, Nirmala Bhatta","doi":"10.33314/jnhrc.v22i04.4494","DOIUrl":"10.33314/jnhrc.v22i04.4494","url":null,"abstract":"<p><strong>Background: </strong>Proper nutrition counselling on healthy food habit to all pregnant women can be a strong weapon to achieve good health of mothers as well as healthy offspring. The main objective of this research was to assess the effectiveness of nutritional counseling on dietary intake and nutritional status of pregnant women.</p><p><strong>Methods: </strong>Quasi-experimental research design was used to evaluate the effectiveness of nutritional counselling on dietary intake and nutritional status of pregnant women. The study area was chosen based on nonprobability purposive sampling technique and 110 participants who were pregnant before 20 weeks of gestation were included in the study who attended district hospital Lamahi and health post of Sisahaniya, Dang. Risults: Mid Upper Arm Circumference (MUAC) measurement of pregnant women showed that 11.8% pregnant women were malnourished (MUAC <22cm) before intervention. The proportion of MUAC measurement improved after nutritional counseling (4.5%). Almost all participants consumed rice, and roti as main foods. Frequency of consuming dal, green vegetables, fruits, milk and milk products, meat, fish, and egg increased after nutrition counseling. The result indicated that the consumption of carbohydrate, protein, fat and energy increased after nutrition counseling (Carbohydrate-226 vs 289g, protein- 65 vs 77g, fat- 43 vs 50g, energy- 1648 vs 2041kcal).</p><p><strong>Conclusions: </strong>Maternal nutrition during pregnancy is crucial for achieving healthy maternal and fetal outcomes. Nutrition counselling showed positive effects on nutritional status of pregnant women. Thus, nutrition counselling is essential for all pregnant women. It should be a major part of Antenatal care service to all pregnant women in Nepal.</p>","PeriodicalId":16380,"journal":{"name":"Journal of Nepal Health Research Council","volume":"22 4","pages":"772-777"},"PeriodicalIF":0.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Self-Care Practices among Patients with Diabetes Mellitus.","authors":"Tara Roka, Dawa Futi Sherpa, Asmita Basnet","doi":"10.33314/jnhrc.v22i04.5136","DOIUrl":"10.33314/jnhrc.v22i04.5136","url":null,"abstract":"<p><strong>Background: </strong>Diabetes Mellitus (DM) requires continuous self-care practices to prevent acute and chronic complications. With the possibility of several physical and psychological complications alongside affecting the social aspect of life, improving self-care is highly important in patients with DM. The aim of this study was to measure self-care practices among patients with DM and factors associated with inadequate self-care.</p><p><strong>Methods: </strong>Information on self-care practices was collected using the summary of Diabetes Self-care Activities (SDSCA) in a hospital based cross-sectional study among 345 participants selected through sequential sampling. Data was analysed using descriptive and inferential statistics and results were presented with proportions and odds ratios with a 95% confidence interval (CI).</p><p><strong>Results: </strong>We found that 30.7% of the participants had adequate self-care practices across all domains. A fairly substantial proportion had adequate self-care in diet and exercise related care with 87.5% and 65.5%, respectively. However, with foot care and blood sugar monitoring related care only a small to negligible proportion had an adequate level of self-care. Multivariate analysis showed that participants aged 65 years and above had higher odds of having inadequate self-care practices (aOR:5.20; 95%CI: 2.20-12.33); and those with diabetes for more than five years had twice the odds (aOR:2.10; 95%CI: 1.15-3.83) of having inadequate self-care.</p><p><strong>Conclusions: </strong>A large proportion of the participants had inadequate self-care practices, and this was even poorer in domains of foot care and blood sugar monitoring. Age of the participants, marital status and duration of illness were factors independently associated with inadequate self-care. Targeted behavior change interventions for patients visiting hospitals and health care centers in Nepal could improve self- care practices among patients with DM.</p>","PeriodicalId":16380,"journal":{"name":"Journal of Nepal Health Research Council","volume":"22 4","pages":"691-698"},"PeriodicalIF":0.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cutaneous Larva migrans: A Case Series of a Skin-related Neglected Tropical Diseases from Nepal.","authors":"Shraddha Shrestha, Shashi Hirachan, Niraj Parajuli","doi":"10.33314/jnhrc.v22i03.5210","DOIUrl":"10.33314/jnhrc.v22i03.5210","url":null,"abstract":"<p><p>Cutaneous larva migrans is a tropical dermatosis acquired through the helminthic infection. It is caused by penetration of animal hookworm larva in patient with history of walking barefoot on soil or beaches or with history of travel to tropical areas. It usually presents clinically as a pruritic serpiginous lesion with a trailing. Here, we report three cases who presented as asymptomatic to pruritic thread like serpiginous lesion on cutaneous examination. Cutaneous larva migrans was diagnosed clinically and proper treatment was done with complete regression of manifestations within a week. Although the condition is self-limiting, it is an under-diagnosed entity leading to delay in treatment and exacerbation of clinical manifestations including rare pulmonary manifestation called Loefflers syndrome. Keywords: Creeping eruption; ivermectin; larva migrans; skin-NTDs.</p>","PeriodicalId":16380,"journal":{"name":"Journal of Nepal Health Research Council","volume":"22 3","pages":"651-653"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Knowledge and Attitude Towards Human Papilloma Virus and Human Papilloma Virus Vaccine.","authors":"Sandesh Poudel, Snigdha Rai, Shree Prasad Adhikari, Sheela Dhakal, Nisha Rai, Preetam Chandra Upadhyaya, Pushkal Shah","doi":"10.33314/jnhrc.v22i03.5396","DOIUrl":"10.33314/jnhrc.v22i03.5396","url":null,"abstract":"<p><strong>Background: </strong>Human papilloma virus is the leading cause of cervical cancer with Human papilloma virus 16 and 18 being the commonest variants. The primary prevention by vaccination against HPV is finally gaining its momentum. This study aimed to evaluate the knowledge and attitude towards Human papilloma virus and Human papilloma virus vaccine and highlighted on the setback of their inadequate knowledge.</p><p><strong>Methods: </strong>This was a community based cross sectional study done among 120 women who attended cervical cancer screening camp at satellite clinic of Paropakar Maternity and Women`s Hospital at Bhaisepati of Kathmandu district. The interview was done one on one with a preformed questionnaire. Data was primarily entered in an individual form and analysis was done using SPSS version 23 program and was depicted in tables, diagrams and chart.</p><p><strong>Results: </strong>The mean age of the women was 41.8±9.9 with majority belonging to age group 41-50 years (47.16%), 88 (74%) women were multiparous,59 (49%) were uneducated and 50 (33%) were previously screened for cervical cancer. Among 27 (22%) of the women who had heard about HPV and knew that it causes cervical cancer, most of them have heard from social media while 110(91.6%) did not know about its vaccine and its availability while 100% of the participants had positive attitude towards receiving the information and keen on vaccinating their daughters.</p><p><strong>Conclusions: </strong>Knowledge and awareness of Human Papilloma Virus and its vaccine still remains low among the women in our society. However, there was high acceptance of HPV vaccine, indicating potentially high uptake rates in these communities.</p>","PeriodicalId":16380,"journal":{"name":"Journal of Nepal Health Research Council","volume":"22 3","pages":"622-626"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Namita Ghimire, Sony Pandey, Pramod Joshi, Ramesh Kant Adhikari
{"title":"Ethical Approval in Nepal: Barriers or Facilitators?","authors":"Namita Ghimire, Sony Pandey, Pramod Joshi, Ramesh Kant Adhikari","doi":"10.33314/jnhrc.v22i03.5057","DOIUrl":"10.33314/jnhrc.v22i03.5057","url":null,"abstract":"<p><p>Any research involving human participants requires review and approval from an authorized research ethics committee to safeguard participant's rights, dignity and welfare while ensuring the scientific validity of the research. Ethical approval is mandatory before initiating or ecruiting study participants. It is also a prerequisite for publishing research findings in scientific journals contributing to ensuring the quality of scientific knowledge. The ethical review process focuses on the assessment of potential risks to the participants as well as the research team focusing on how such risks are identified, minimized and managed. This paper provides an overview of the Nepal Health Research Council's ethical review and approval process for both national and international researchers intending to conduct health research in Nepal. Despite this, the Nepalese ethics committee and researcher face several challenges, including limited awareness of responsible conduct of research, limited training opportunities, unclear clinical trial guidelines, bureaucratic hurdles, and frequent staff turnover in research governance. This paper highlights these challenges and aims to support both researchers and the Ethics Committee in promoting the responsible conduct of health research in Nepal. Keywords: Ethical issues; ethical review and approval; Nepal and research.</p>","PeriodicalId":16380,"journal":{"name":"Journal of Nepal Health Research Council","volume":"22 3","pages":"647-650"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143373531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hypertension and its Associated Factors in a Middle-Aged Population.","authors":"Tulsi Ram Bhandari, Shishir Paudel, Anisha Chalise, Jenny Ojha, Grish Paudel, Bhushan Khatiwada, Uday Narayan Yadav","doi":"10.33314/jnhrc.v22i03.5238","DOIUrl":"10.33314/jnhrc.v22i03.5238","url":null,"abstract":"<p><strong>Background: </strong>Hypertension is a major risk factor for cardiovascular diseases, chronic kidney disease, and dementia. Early detection and management are crucial for preventing these complications. However, many people lack awareness regarding their blood pressure. The study aimed to assess the prevalence of hypertension and its associated factors in rural communities.</p><p><strong>Methods: </strong>This cross-sectional study was conducted among 525 middle-aged (35-60 years) residents of the Rupa Rural Municipality, Nepal, from August to December 2020. Chi-square test and multivariate logistic regression were performed to identify the factors associated with hypertension at a 5% level of significance.</p><p><strong>Results: </strong>More than half (50.9%) of the respondents had normal to elevated systolic pressure, while only one-third (33.9%) had normal to elevated diastolic pressure. Only 47.4% of the hypertensive participants were aware of their hypertensive condition. Being a male (aOR: 1.903; 95% CI: 1.184-3.030), in middle age of 45-55 years (aOR: 2.002; 95% CI: 1.152-3.478), having basic education (aOR: 2.014; 95% CI:1.174-3.455), currently consuming alcohol (aOR: 1.923; 95% CI: 1.095-3.375), and being overweight/ obese (aOR: 1.899; 95% CI: 1.262-2.859) were identified as significant factors associated with hypertension.</p><p><strong>Conclusions: </strong>The studys findings emphasize the urgency of interventions to improve awareness of hypertension and its management to improve health outcomes. Targeted interventions will have an opportunity to reduce the burden of hypertension which is an important risk factor for cardiovascular diseases among the middle-aged population.</p>","PeriodicalId":16380,"journal":{"name":"Journal of Nepal Health Research Council","volume":"22 3","pages":"582-591"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143373996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of Medical Student Syndrome among Medical Students of Nepal.","authors":"Samata Nepal, Alok Atreya, Swasti Bhandari, Laxmi Prasad Sapkota, Ritesh G Menezes, Laxman Gnawali, Kishor Adhikari","doi":"10.33314/jnhrc.v22i03.5330","DOIUrl":"10.33314/jnhrc.v22i03.5330","url":null,"abstract":"<p><strong>Background: </strong>Medical student syndrome (MSS) entails the development of symptoms of the same disease as the one being studied in medical students. This study aimed to determine the prevalence of Medical student syndrome among medical students in Nepal and identify associated factors.</p><p><strong>Methods: </strong>A Cross-sectional study was conducted at Lumbini Medical College Palpa, Nepal on medical students. Google form-based questionnaire was made, and the link was distributed to the students. A cut-off score was derived for Medical student syndrome. Students whose scores exceeded this threshold were categorized as having experienced Medical student syndrome. The responses received from the consenting students were downloaded in a Microsoft Excel spreadsheet and exported to SPSS v 26 and analysed.</p><p><strong>Results: </strong>The overall prevalence of Medical student syndrome was 17.8%. There was no significant difference in Medical student syndrome scores between genders (p = 0.801). However, year of study significantly influenced Medical student syndrome scores (p = 0.001, η² = 0.069), with final year students reporting higher scores.</p><p><strong>Conclusions: </strong>This cross-sectional study revealed a significant prevalence of Medical Student Syndrome among medical students in Nepal, with nearly 18% reporting symptoms of the condition.</p>","PeriodicalId":16380,"journal":{"name":"Journal of Nepal Health Research Council","volume":"22 3","pages":"616-621"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Awareness of Eye Donation among University Students.","authors":"Shailesh Mani Pokharel, Nabin Lamichhane, Sushil Regmi","doi":"10.33314/jnhrc.v22i03.5055","DOIUrl":"10.33314/jnhrc.v22i03.5055","url":null,"abstract":"<p><strong>Backgrounds: </strong>Eye donation is an act of donating, one's eyes, mostly the cornea after his/her death. According to World Health Organization (WHO) estimates every 5 second, someone goes blind. There are currently about 45 million blind people in the world which increases by 1 to 2 million every year. The study aimed to identify and explore the awareness of eye donation among university students in Morang, Nepal.</p><p><strong>Methods: </strong>A descriptive cross-sectional study was conducted on Undergraduate Students of Purbanchal University School of Health Sciences a constituent college of Purbanchal University situated in Sundarharaicha Municipality of Morang District of Nepal. Population proportionate simple random sampling technique was applied to allocate the sample size.</p><p><strong>Results: </strong>Among the total of 177 respondents, 22.0% are from the Pharmacy faculty, 22.6% from Public Health, and 55.4% from Nursing. Out of the total respondents, 98.9% were aware of eye donation, while only 1.1% had no awareness. About 86.9%, of the respondents correctly identified the cornea as a donatable part. However, a smaller percentage mentioned the retina (4.0%), eye ball (6.9%), and lens (2.3%).</p><p><strong>Conclusions: </strong>The findings of the study on awareness of eye donation suggest the need for targeted educational interventions to enhance understanding the parts of eye for donation and avoiding the misconceptions about various aspects of eye donation among Health Sciences students.</p>","PeriodicalId":16380,"journal":{"name":"Journal of Nepal Health Research Council","volume":"22 3","pages":"543-548"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}