Journal of Nepal Health Research Council最新文献

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Effect of Altitude on Metabolic Syndrome. 海拔对代谢综合征的影响。
Journal of Nepal Health Research Council Pub Date : 2025-06-29 DOI: 10.33314/jnhrc.v23i01.5525
Mahendra Prasad Bhatt, Manavi Poudel, Sushant Pokhrel, Anuradha Kadel, Mukesh Joshi
{"title":"Effect of Altitude on Metabolic Syndrome.","authors":"Mahendra Prasad Bhatt, Manavi Poudel, Sushant Pokhrel, Anuradha Kadel, Mukesh Joshi","doi":"10.33314/jnhrc.v23i01.5525","DOIUrl":"https://doi.org/10.33314/jnhrc.v23i01.5525","url":null,"abstract":"<p><strong>Background: </strong>Metabolic syndrome is a constellation of overweight/obesity, hypertension, and disturbances in lipid and carbohydrate metabolism. Hypoxic and hypobaric conditions of high altitude alter the use of energy producing metabolic fuels which may secondarily affect lipid and blood glucose concentrations. Thus, this study aims to assess prevalence and risk factors of the metabolic syndrome in high and low altitude inhabitants of Nepal.</p><p><strong>Methods: </strong>A hospital based descriptive cross-sectional study was carried out including 58 individuals from high altitude and 58 individuals from low altitude attending Manmohan Memorial Teaching Hospital, Kathmandu. Anthropometric measurements and blood pressure were recorded and blood samples were obtained for laboratory analysis. The samples were analyzed for fasting glucose, triglycerides, total cholesterol, high density lipoprotein cholesterol and low density lipoprotein cholesterol as per the standard guidelines.</p><p><strong>Results: </strong>Among the study group, 31.8% of high altitude and 68.2% of low altitude are found to have metabolic syndrome according to National Cholesterol Education Program Adult Treatment PlanIII and 35.5% of high altitude and 64.5% of low altitude are found to have metabolic syndrome according to HJSS criteria. The most prevalent defining components were low high density lipoprotein cholesterol (38.8%), high triglyceride (36.2%), elevated fasting blood sugar (33.6%) and Hypertension (34.4%). Among the lifestyle factors, alcohol consumption, unhealthy diet and physical inactivity were found to be an independent risk factors for MetS.</p><p><strong>Conclusions: </strong>High altitude inhabitants have significantly lower metabolic syndrome than that of low altitude inhabitants because of less physical activities in their work and sedentary. Thus, encouragement of food habit, healthy lifestyle, and timely health screening and monitoring help in prevention of metabolic syndrome.</p>","PeriodicalId":16380,"journal":{"name":"Journal of Nepal Health Research Council","volume":"23 1","pages":"145-151"},"PeriodicalIF":0.0,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144799309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Association Between ABO Blood Groups and Adenomyosis. ABO血型与bbb的关系。
Journal of Nepal Health Research Council Pub Date : 2025-06-29 DOI: 10.33314/jnhrc.v23i01.5621
Sunita Pun, Neebha Ojha, Poonam Koirala
{"title":"The Association Between ABO Blood Groups and Adenomyosis.","authors":"Sunita Pun, Neebha Ojha, Poonam Koirala","doi":"10.33314/jnhrc.v23i01.5621","DOIUrl":"https://doi.org/10.33314/jnhrc.v23i01.5621","url":null,"abstract":"<p><strong>Background: </strong>Several studies have investigated the relationships between female reproductive diseases and ABO blood groups. However, evidence regarding the potential association between ABO blood groups and adenomyosis remains limited. The aim of the study, thus, was to investigate the association between ABO blood groups and the risk of developing adenomyosis in Nepalese women.</p><p><strong>Methods: </strong>A cross-sectional study was conducted at the department of obstetrics and gynecology, Tribhuvan University Teaching Hospital, Maharajgunj, from 2016 to 2017. Statistical analysis was done using Statistical Package for Social Sciences (SPSS, 29). Odd ratio with their corresponding 95% confidence intervals, and P-value were calculated and analyzed. A P-value equal or < 0.05 was considered statistically significant.  Results: A total of 249 with recorded ABO groups were included in this study. Of these, 85 cases (34%) were histologically confirmed to have adenomyosis. The most frequent ABO blood group was B (43%), while the least frequent group was AB (6%). Women with blood group B had a significantly increased risk of developing adenomyosis, with an odds ratio of 2.3 (95% CI: 1.22-4.43, P value = 0.01). Conversely, blood group A was associated with a significantly reduced risk of adenomyosis, with an odds ratio of 0.41 (95% CI: 0.19-0.89, P value= 0.03).       Conclusions: This study demonstrated that women with blood group B have a 2.3-fold higher risk of developing adenomyosis, whereas those with blood group A may have a protective effect. Multicenter studies with larger sample sizes and diverse demographics groups are needed to substantiate these findings.</p><p><strong>Key words: </strong>Adenomyosis; ABO blood group; risk factors.</p>","PeriodicalId":16380,"journal":{"name":"Journal of Nepal Health Research Council","volume":"23 1","pages":"176-179"},"PeriodicalIF":0.0,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144799310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Menstrual Hygiene among Female Prisoners of Jhapa and Morang Districts of Nepal. 尼泊尔Jhapa和Morang地区女性囚犯的月经卫生状况。
Journal of Nepal Health Research Council Pub Date : 2025-06-29 DOI: 10.33314/jnhrc.v23i01.5394
Laxmi Gautam, Mamata Regmi, Amrit Bist
{"title":"Menstrual Hygiene among Female Prisoners of Jhapa and Morang Districts of Nepal.","authors":"Laxmi Gautam, Mamata Regmi, Amrit Bist","doi":"10.33314/jnhrc.v23i01.5394","DOIUrl":"10.33314/jnhrc.v23i01.5394","url":null,"abstract":"<p><strong>Background: </strong>Female prisoners constitute a minority of prison population and their special health care needs are often neglected. This study aims to assess the knowledge of menstruation and menstrual hygiene practices of female prisoners of Jhapa and Morang.</p><p><strong>Methods: </strong>A cross sectional study was conducted among 140 female prisoners of Jhapa and Morang District Prison of Eastern Nepal through a pretested semi structured questionnaire and face to face interview. Logistic regression model was used to assess the factors associated with the outcome variable using an adjusted odds ratio with a 95% CI, and p-value <0.05 was considered statistically significant.</p><p><strong>Results: </strong>The study showed that 65% of the female prisoners had adequate knowledge about menstruation. Half of the respondents (50%) had good menstrual hygiene practice. Majority of the respondents (67.9%) used sanitary pad and nearly one third (32.9%) used clothes as absorbent material during menstruation. Dysmenorrhea was the major health problem (31.9%) reported by prisoners. Respondent's knowledge on menstruation was significantly associated with educational status (AOR: 6.775, 95% CI: 2.089-21.87), marital status (AOR: 3.375, 95% CI: 1.979- 11.63) and former residence (AOR: 5.014, 95% CI: 2.196-11.44) in multivariate analysis.</p><p><strong>Conclusions: </strong>More than one third of female prisoners had inadequate knowledge about menstruation and half menstrual hygiene practices were unsatisfactory. This demonstrates a need to design health education programme and foster advocacy to improve the knowledge and promote safe hygienic practice of female prisoners during menstruation.</p>","PeriodicalId":16380,"journal":{"name":"Journal of Nepal Health Research Council","volume":"23 1","pages":"114-120"},"PeriodicalIF":0.0,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144799339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spectrum of Obstetrics Case Referrals. 产科病例转诊谱。
Journal of Nepal Health Research Council Pub Date : 2025-06-29 DOI: 10.33314/jnhrc.v23i01.5316
Asmita Ghimire, Reshika Shrestha, Jeshika Yadav, Ishwor Thapaliya, Sangrila Sapkota, Susmita Khatiwoda, Neebha Ojha
{"title":"Spectrum of Obstetrics Case Referrals.","authors":"Asmita Ghimire, Reshika Shrestha, Jeshika Yadav, Ishwor Thapaliya, Sangrila Sapkota, Susmita Khatiwoda, Neebha Ojha","doi":"10.33314/jnhrc.v23i01.5316","DOIUrl":"https://doi.org/10.33314/jnhrc.v23i01.5316","url":null,"abstract":"<p><strong>Background: </strong>Maternal health is an important focus for ensuring the well-being of both mothers and their babies. Maternal and fetal mortality which is a burning issue especially in third world countries can be reduced significantly with right obstetric referral. This study reviewed the primary reasons, time, distance, and pattern of obstetric cases referred to a tertiary center.</p><p><strong>Methods: </strong>This descriptive study was conducted after taking ethical approval {Approval number 136 (6-11) E2} from the review board of Maharajgunj Medical Campus, Nepal, and data of three years from 1st August 2020- 31st September 2023 were analyzed from medical records. The study included all referral cases aged 18-45 years who were past 28 weeks of gestation till 42 days post-delivery. Women who had incomplete medical records were excluded from the study. A continuous convenience sampling method was used. The point estimate was calculated at a 95% confidence interval.</p><p><strong>Results: </strong>Among 174 referred cases, 84 (48.28%) were from the government district-level hospitals with the predominant reason being medical disorders complicating pregnancy 136 (78.17%). The majority of cases 94 (54.02%) were referred during the intrapartum period.</p><p><strong>Conclusions: </strong>Medical disorders complicating pregnancy were the primary cause for the referral in obstetrics cases, notably from district-level hospitals having less manpower to deal with those cases.</p>","PeriodicalId":16380,"journal":{"name":"Journal of Nepal Health Research Council","volume":"23 1","pages":"89-93"},"PeriodicalIF":0.0,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144799288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison Between Hyperbaric Bupivacaine with and Without Fentanyl in Reducing Visceral Pain During Cesarean Delivery Under Spinal Anaesthesia. 高压布比卡因加芬太尼与不加芬太尼对减轻脊柱麻醉剖宫产时内脏疼痛的比较。
Journal of Nepal Health Research Council Pub Date : 2025-06-29 DOI: 10.33314/jnhrc.v23i01.5397
Rashmi Thapa, Pooja Paudyal, Bishwas Pradhan, Megha Koirala, Bashu Dev Parajuli
{"title":"Comparison Between Hyperbaric Bupivacaine with and Without Fentanyl in Reducing Visceral Pain During Cesarean Delivery Under Spinal Anaesthesia.","authors":"Rashmi Thapa, Pooja Paudyal, Bishwas Pradhan, Megha Koirala, Bashu Dev Parajuli","doi":"10.33314/jnhrc.v23i01.5397","DOIUrl":"10.33314/jnhrc.v23i01.5397","url":null,"abstract":"<p><strong>Background: </strong>Visceral pain occurred during cesarean delivery during spinal anesthesia can be decreased with a higher dose of bupivacaine. However, larger doses of bupivacaine increases the risk of high sensory block. We hypothesized that addition of fentanyl to bupivacaine intrathecally could intensifies the sensory block and improves the quality of intraoperative analgesia. The aim of this study is to compare incidence of visceral pain between hyperbaric bupivacaine with or without fentanyl during cesarean delivery under spinal anesthesia.</p><p><strong>Methods: </strong>In this prospective randomized controlled trial, 72 term parturient with ASA PS II undergoing cesarean delivery under spinal anesthesia were randomly distributed into two groups. Group B received 2.2ml (11mg) of 0.5% hyperbaric bupivacaine while Group BF received 2 ml (10mg) of 0.5% hyperbaric bupivacaine and 0.2ml (10µg) of fentanyl intrathecally. Incidence of intraoperative visceral pain, maternal hemodynamics, side effects and APGAR score were compared.</p><p><strong>Results: </strong>During exteriorization of uterus, 11% of parturient in Group BF and 44% parturient in Group B complained of intraoperative visceral pain with significant difference between two group (p=0.002). The intraoperative rescue analgesia was given in 22 % parturient in Group BF and 33% parturient in Group B (p= 0.29). Maternal vital parameters like blood pressure, heart rate, oxygen saturation and respiratory rate were comparable between two groups. APGAR score was similar in both groups.</p><p><strong>Conclusion: </strong>Addition of intrathecal fentanyl to hyperbaric bupivacaine was effective in reducing intraoperative visceral pain during cesarean delivery with stable maternal hemodynamics and without neonatal side effects.</p>","PeriodicalId":16380,"journal":{"name":"Journal of Nepal Health Research Council","volume":"23 1","pages":"25-30"},"PeriodicalIF":0.0,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144799304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and Risk Factors of High Blood Pressure among Elderly People. 老年人高血压患病率及危险因素分析。
Journal of Nepal Health Research Council Pub Date : 2025-06-29 DOI: 10.33314/jnhrc.v23i01.5223
Keshab Parajuli, Mahendra Prasad Sharma, Raju Ghimire, Kshitij Karki
{"title":"Prevalence and Risk Factors of High Blood Pressure among Elderly People.","authors":"Keshab Parajuli, Mahendra Prasad Sharma, Raju Ghimire, Kshitij Karki","doi":"10.33314/jnhrc.v23i01.5223","DOIUrl":"https://doi.org/10.33314/jnhrc.v23i01.5223","url":null,"abstract":"<p><strong>Background: </strong>High Blood Pressure, a prevalent condition exacerbated by population growth, disproportionately affects the elderly, with over two-thirds of individuals aged 65 and above affected. This study aimed to evaluate the prevalence and risk factors of high blood pressure among elderly residents of Chandragiri Municipality in Kathmandu.</p><p><strong>Methodology: </strong>A cross-sectional was applied, and the respondents were selected from randomly chosen wards of Chandragiri Municipality. Elderly individuals aged over 60 years residing in the area, regardless of permanency, were included. Data analysis was conducted using SPSS software, with the Chi-square test employed to assess associations between high blood pressure and various risk factors at a significance level of 5%.</p><p><strong>Results: </strong>The study included 418 individuals, of whom 48.8% were currently suffering from high blood pressure. The majority was male 55.5% and married 73.7%, with Chhetri 45.2% and Brahmin 40.7% being the most prevalent ethnic groups. Most respondents were illiterate 44.3% and resided in joint families 68.4%. Reported risk factors for high blood pressure included tobacco smoking 37.3%, alcohol consumption 36.1%, and non-vegetarian diets 85.9%.</p><p><strong>Conclusion: </strong>Significant relationships were observed between blood pressure and age, sex, marital status, tobacco smoking, and alcohol consumption. Conversely, religion, ethnicity, education level, family type, BMI, diet type, and physical activity did not exhibit noteworthy associations with high blood pressure in this sample. These findings underscore the multifactorial nature of high blood pressure and its diverse risk factors.</p>","PeriodicalId":16380,"journal":{"name":"Journal of Nepal Health Research Council","volume":"23 1","pages":"65-72"},"PeriodicalIF":0.0,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144799283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum Vitamin B12 Level in Children with Type 1 Diabetes. 1型糖尿病儿童血清维生素B12水平
Journal of Nepal Health Research Council Pub Date : 2025-06-29 DOI: 10.33314/jnhrc.v23i01.4726
Santosh Pradhan, Subhana Thapa, Pradeep Krishna Shrestha, Bharat Jha
{"title":"Serum Vitamin B12 Level in Children with Type 1 Diabetes.","authors":"Santosh Pradhan, Subhana Thapa, Pradeep Krishna Shrestha, Bharat Jha","doi":"10.33314/jnhrc.v23i01.4726","DOIUrl":"https://doi.org/10.33314/jnhrc.v23i01.4726","url":null,"abstract":"<p><strong>Background: </strong>Type 1 Diabetes Mellitus is known to be associated with multiple co-morbidities. Vitamin B12 deficiency is a potential co- morbidity that might have been overlooked in these patients. The aim of this study is to evaluate the serum level of vitamin B 12 in a well-defined population of Type 1 diabetes.</p><p><strong>Methods: </strong>The cross sectional study carried out on 40 patients with Type 1 Diabetes Mellitus visiting endocrinology unit in Kanti children's Hospital, Kathmandu, Nepal. Thirty healthy non diabetics were also selected. Serum C-peptide, vitamin B12, creatinine, blood glucose level and glycosylated hemoglobin were assessed in both groups. SPSS ver. 22 was used to analyze the data.</p><p><strong>Results: </strong>The mean serum vitamin B12 level of the diabetic group was 206.92±82.18 pmol/L. Among the population 40.0% i.e. 16 out of 40 were found to be deficient and 37.5 % i.e. 15 out of 40 were subclinically deficient. Whereas the mean serum vitamin B12 level of the non diabetic group was 340.71±136.02pmol/L. Out of 30 only 2(6.7%) were deficient, 8 (26.75%) were found to be subclinically deficient. Significant difference was noticed in the mean serum level of vitaminB12 between these two groups.</p><p><strong>Conclusions: </strong>This study shows the presence of low serum vitamin B12 levels in Type 1 Diabetics. The routine screening for this condition along with confirmatory test and detail clinical examination could benefit the patients with Type 1 diabetes.</p>","PeriodicalId":16380,"journal":{"name":"Journal of Nepal Health Research Council","volume":"23 1","pages":"14-20"},"PeriodicalIF":0.0,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144799287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Case of Crigler-Najjar Syndrome Type 2. 罕见的Crigler-Najjar综合征2例。
Journal of Nepal Health Research Council Pub Date : 2025-06-29 DOI: 10.33314/jnhrc.v23i01.5352
Anil Kumar Shrestha, Sangay Chultim Sherpa, Asmita Karki, Sumit Agrawal, Deepak Raj Paudel
{"title":"A Rare Case of Crigler-Najjar Syndrome Type 2.","authors":"Anil Kumar Shrestha, Sangay Chultim Sherpa, Asmita Karki, Sumit Agrawal, Deepak Raj Paudel","doi":"10.33314/jnhrc.v23i01.5352","DOIUrl":"https://doi.org/10.33314/jnhrc.v23i01.5352","url":null,"abstract":"<p><p>Crigler-Najjar Syndrome Type 2 (CNS2) is a rare autosomal recessive disorder characterized by unconjugated hyperbilirubinemia due to partial deficiency of the enzyme uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1). We present a case of a 13-month-old male admitted to Kanti Children's Hospital with persistent jaundice since birth. Diagnostic evaluation accompanied by gene sequencing confirmed CNS2 and the patient was effectively managed with orally administered phenobarbitone. CNS2 can be distinguished from other potential causes of unconjugated hyperbilirubinemia based on bilirubin concentration and the affected patient's response to phenobarbitone. Genetic counselling is essential for the recognition and prevention of severe hyperbilirubinemia which, in the absence of timely medical intervention, may lead to neurotoxicity. Keywords: Case report; crigler-Najjar syndrome; genetic counseling; phenobarbitone; unconjugated hyperbilirubinemia.</p>","PeriodicalId":16380,"journal":{"name":"Journal of Nepal Health Research Council","volume":"23 1","pages":"208-210"},"PeriodicalIF":0.0,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144799378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Level of Serum Enzymes and Hormones in Patients with Miscarriage. 流产患者血清酶和激素水平的变化。
Journal of Nepal Health Research Council Pub Date : 2025-06-29 DOI: 10.33314/jnhrc.v23i01.5154
Rupesh Kumar Shreewastav, Munzal Yadav
{"title":"The Level of Serum Enzymes and Hormones in Patients with Miscarriage.","authors":"Rupesh Kumar Shreewastav, Munzal Yadav","doi":"10.33314/jnhrc.v23i01.5154","DOIUrl":"https://doi.org/10.33314/jnhrc.v23i01.5154","url":null,"abstract":"<p><strong>Background: </strong>The level of various enzymes and thyroid hormones in blood get altered during miscarriage, which can have predictive value or importance as a biomarker for the diagnosis. The aim of the present study is to validate the alteration in the level of serum enzymes and thyroid hormones in patients suffering with miscarriage in a tertiary care hospital in Nepal.</p><p><strong>Methods: </strong>A descriptive cross-sectional study was carried out on patients suffering with miscarriage and admitted for treatment in Nobel Medical College Teaching Hospital. Demographic data were recorded in a predesigned performa. The level of various enzymes and thyroid hormones were estimated from the blood sample of patients in the department of biochemistry laboratory. Data were entered in MS excel and analyzed by statistical package for the social sciences Version version 20.0 Results: The total number of patients suffering from miscarriage and enrolled in the study was 86. The mean value of serum gamma glutamyl transferase, lactate dehydrogenase and adenosine deaminase in these patients were 22.67±8.22, 289.6±126.9 and 21.3±9.9 IU/ml respectively, which were significantly higher (p=<0.0001, 0.0004, 0.0179 respectively) when compared to healthy pregnant women. Thyroid dysfunction was noted in 15 (17.44%) patients, out of that Subclinical hypothyroidism was most common and affected 8(9.3%) individuals.</p><p><strong>Conclusions: </strong>The mean value of serum gamma glutamyl transferase, lactate dehydrogenase and adenosine deaminase in case of miscarriage was found to be elevated significantly and thyroid dysfunction was also noted to small fraction of patients suffering from miscarriage with Subclinical hypothyroidism being the most common.</p>","PeriodicalId":16380,"journal":{"name":"Journal of Nepal Health Research Council","volume":"23 1","pages":"59-64"},"PeriodicalIF":0.0,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144799311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Job Satisfaction among Health Workforce in Medical Colleges of Nepal: A Mixed Method. 尼泊尔医学院医务人员工作满意度:一种混合方法。
Journal of Nepal Health Research Council Pub Date : 2025-06-29 DOI: 10.33314/jnhrc.v23i01.5417
Dipak Prasad Dahal, Nidhi Gupta
{"title":"Job Satisfaction among Health Workforce in Medical Colleges of Nepal: A Mixed Method.","authors":"Dipak Prasad Dahal, Nidhi Gupta","doi":"10.33314/jnhrc.v23i01.5417","DOIUrl":"https://doi.org/10.33314/jnhrc.v23i01.5417","url":null,"abstract":"<p><strong>Background: </strong>The medical sector in the society and its significant role of job satisfaction will improve the health workforce performance. Presently staffs/workforce management in medical colleges became more challenges. The purpose of the study was to investigate the level of job satisfaction and associated factors in medical colleges of Nepal.</p><p><strong>Methods: </strong>The study employed descriptive, cross-sectional study with the relevant respondents' such as doctors, nurses and administrative staffs working in different medical colleges of Nepal. The study was conducted within the affiliated college of Kathmandu University School of Medical Sciences (KUSMS). Simple random sampling method was used to select respondents. A total sample size of 108 for quantitative and 18 for qualitative was collected, using the formula from Charan and Biswas, 2013. For qualitative study, we used purposive convenience sampling strategy to enroll the health workers for key informant interview to gather data on job satisfaction, impression and experience about their job.</p><p><strong>Results: </strong>34.3% of the respondents, we surveyed were not satisfied with their job while 65.7% were satisfied with their current job. It has also been discovered that the delivery of high-quality health care depends on the level of job satisfaction with the healthcare organization.</p><p><strong>Conclusions: </strong>There was a significant relationship between job satisfaction of health workforce and its' associated factors in medical college of Nepal. A focus on improving work environment through increased financial motivation and career development opportunities as well as investing in health insurance for diseases with increased resources support is recommended to improve job satisfaction.</p>","PeriodicalId":16380,"journal":{"name":"Journal of Nepal Health Research Council","volume":"23 1","pages":"180-189"},"PeriodicalIF":0.0,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144799337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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