Journal of Microscopy and Ultrastructure最新文献

{"title":"Myofibroblasts in Odontogenic Cysts and Tumors: An Immunohistochemical Study.","authors":"Soujanya Pinisetti,&nbsp;Durgaprasad Tadi,&nbsp;Ravikanth Manyam","doi":"10.4103/jmau.jmau_64_21","DOIUrl":"https://doi.org/10.4103/jmau.jmau_64_21","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this study was to assess immunohistochemically the presence of myofibroblasts both qualitatively and quantitatively in odontogenic cysts and tumors and to compare with the control cases of squamous cell carcinoma and to correlate the results with biologic behavior of these lesions.</p><p><strong>Materials and methodology: </strong>Formalin-fixed, paraffin-embedded blocks of odontogenic cysts and tumors were retrieved from institutional archives. The sample size is 40; these include ten cases of odontogenic keratocyst (OKC) (<i>n</i> = 10), five cases of dentigerous cyst (<i>n</i> = 5), ten cases of solid ameloblastoma (<i>n</i> = 10), and five cases of unicystic ameloblastoma (<i>n</i> = 5). Ten cases of squamous cell carcinoma (<i>n</i> = 10) served as control. Sections were taken and stained immunohistochemically using alpha-smooth muscle actin for evaluation of myofibroblasts. The number of positive stromal cells was evaluated both for quantitative and qualitative analyses.</p><p><strong>Results: </strong>The present study showed that the mean number of myofibroblasts among the odontogenic cysts and tumors was higher in locally aggressive lesions such as OKC (23.79 ± 19.95), solid ameloblastoma (26.38 ± 17.00), and unicystic ameloblastoma (20.74 ± 14.86) which were comparable to squamous cell carcinoma (21.49 ± 9.76) when compared to benign lesions like dentigerous cyst which showed the least number of myofibroblasts (13.1 ± 7.71). Qualitatively, the staining intensity of myofibroblasts showed a significant variation within the same lesion and among different lesions. There was a distinct difference in the morphology, pattern of arrangement, and distribution of myofibroblasts among the studied lesions.</p><p><strong>Conclusion: </strong>We conclude that the increase in the number of myofibroblasts could be one of the contributory factors for the locally aggressive behavior of benign lesions such as ameloblastomas and OKCs. Further studies are suggested to understand the mechanism by which these important cellular elements exert their effects on stromal and epithelial tissue compartments.</p>","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"11 1","pages":"68-73"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/78/2b/JMAU-11-68.PMC10153737.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9415560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of accuracy of ultrasound guided needle aspiration cytology in the assessment of axilla in breast carcinoma and its correlation with histopathological findings","authors":"Vaishali Shirale, SudhirKumar Jain, RituKumari Saxena, AjayKumar Saxena, S. Rustagi","doi":"10.4103/jmau.jmau_102_22","DOIUrl":"https://doi.org/10.4103/jmau.jmau_102_22","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70799372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The usefulness of gray image fractal analysis – An adjunct tool for the diagnosis of breast lesions at cytology","authors":"K. Amita, Kalappa Prashantha, Rajani Gowda","doi":"10.4103/jmau.jmau_110_22","DOIUrl":"https://doi.org/10.4103/jmau.jmau_110_22","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70799996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bone marrow erythroblastic dysplasia on morphology correlates significantly with flow cytometric apoptosis and peripheral blood eryptosis","authors":"Prashant Sharma, Chander Hans, Rahul Saini, M. Sachdeva, A. Khadwal, P. Bose, R. Das","doi":"10.4103/jmau.jmau_97_22","DOIUrl":"https://doi.org/10.4103/jmau.jmau_97_22","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70802010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral cysticercosis: Importance of early diagnosis and prevention","authors":"Sheetal Choudhari, Kamlesh Dekate, SnehaMasne Deshpande, Snehal Dhumal","doi":"10.4103/jmau.jmau_8_23","DOIUrl":"https://doi.org/10.4103/jmau.jmau_8_23","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70802071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new insight into the classification of clear cell lesions of the oral cavity based on the diagnostic modalities used – A review","authors":"AAlagu Vennila, RebekahChibborah Prabakaran, Narayanarao Gururaj, Alka Kale, SDeenul Fathima, MK Keerthik Lavanya, M Nandhini","doi":"10.4103/jmau.jmau_75_23","DOIUrl":"https://doi.org/10.4103/jmau.jmau_75_23","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135319792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The potential use of salivary OMICs in understanding the pathogenesis and diagnosis of oral and medical diseases","authors":"A. Elsamanoudy, Ahmed Alzahrani, DeemA Alblaihed, DoaaY Jamal, ShimaaT Ibrahim, Ghada A Ajabnoor","doi":"10.4103/jmau.jmau_122_22","DOIUrl":"https://doi.org/10.4103/jmau.jmau_122_22","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70800268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relation of osteopontin expression to tumor-associated macrophages-derived transforming growth factor beta 1 expression in non-small cell lung carcinoma","authors":"Marwa Abd El-Azeem, Shaimaa M. M. Bebars","doi":"10.4103/jmau.jmau_7_23","DOIUrl":"https://doi.org/10.4103/jmau.jmau_7_23","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70801646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maxillary mucormycotic osteonecrosis as a manifestation of Post-COVID-19 infection in non-diabetic patients: Report of two cases","authors":"V Vasanthi, ThamizhanambiTamizh Paavai, Annasamy Rameshkumar, Krishnan Rajkumar, VB Krishnakumar Raja, Veerabahu Muthusubramanian","doi":"10.4103/jmau.jmau_81_23","DOIUrl":"https://doi.org/10.4103/jmau.jmau_81_23","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135318724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Computational protein structural annotations of Mycobacterium tuberculosis thiamine phosphate pyrophosphorylase","authors":"FatenAhmad Alsulaimany","doi":"10.4103/jmau.jmau_59_23","DOIUrl":"https://doi.org/10.4103/jmau.jmau_59_23","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135319791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}