Journal of Microscopy and Ultrastructure最新文献

{"title":"The potential use of salivary OMICs in understanding the pathogenesis and diagnosis of oral and medical diseases","authors":"A. Elsamanoudy, Ahmed Alzahrani, DeemA Alblaihed, DoaaY Jamal, ShimaaT Ibrahim, Ghada A Ajabnoor","doi":"10.4103/jmau.jmau_122_22","DOIUrl":"https://doi.org/10.4103/jmau.jmau_122_22","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70800268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maxillary mucormycotic osteonecrosis as a manifestation of Post-COVID-19 infection in non-diabetic patients: Report of two cases","authors":"V Vasanthi, ThamizhanambiTamizh Paavai, Annasamy Rameshkumar, Krishnan Rajkumar, VB Krishnakumar Raja, Veerabahu Muthusubramanian","doi":"10.4103/jmau.jmau_81_23","DOIUrl":"https://doi.org/10.4103/jmau.jmau_81_23","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135318724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Computational protein structural annotations of Mycobacterium tuberculosis thiamine phosphate pyrophosphorylase","authors":"FatenAhmad Alsulaimany","doi":"10.4103/jmau.jmau_59_23","DOIUrl":"https://doi.org/10.4103/jmau.jmau_59_23","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135319791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does Omeprazole, the Proton-Pump Inhibitor, Affects the Structure of the Kidney of Male Albino Rats? Histological and Laboratory Study.","authors":"Heba M Hussein,&nbsp;Nagwa El-Nefiawy,&nbsp;Haidy F Abdel Hamid,&nbsp;Marwa A Moneim","doi":"10.4103/jmau.jmau_11_21","DOIUrl":"https://doi.org/10.4103/jmau.jmau_11_21","url":null,"abstract":"<p><strong>Introduction: </strong>This study was done to assess the injurious effects of omeprazole by an <i>in vivo</i> experimental study on rat kidneys.</p><p><strong>Materials and methods: </strong>Forty-two adult male albino rats were divided into four groups: Control group (I) in which rats were not administrated any treatment. In Groups IIa, IIb, and IIc rats received daily oral omeprazole in dose of 0.75 mg per kg for 2, 4, and 6 weeks, respectively. At the end of the experiment, blood samples were collected for serum creatinine and blood urea nitrogen measurement. Then, animals were sacrificed, and kidney specimens were processed for paraffin blocks, sectioned and stained with H and E, Mallory trichrome and Periodic acid-Schiff, then examined by the light microscope. Stained sections and image analysis were used to count vacuolated cells, pyknotic nuclei, tubular casts, and area percent of collagen fiber deposition, and then, data were subjected to the statistical analysis.</p><p><strong>Results: </strong>Examination of omeprazole-treated groups showed injury of renal corpuscles, renal tubules, and vascular congestion with inflammatory cell infiltrate in renal interstitium. Thickening of basement membrane with deposition of collagen fibers was also detected. Statistically significant increase in the number of vacuolated cells, pyknotic nuclei, hyaline casts, and area percentage of collagen fiber deposition as compared with the control group was noticed, with deterioration of renal function tests.</p><p><strong>Conclusion: </strong>It was concluded that the long-term use of omeprazole resulted in structural damage of rat renal tissue associated with deterioration of renal function in a time-dependent manner.</p>","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"11 1","pages":"23-33"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/28/5e/JMAU-11-23.PMC10153739.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9470948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myeloperoxidase as a biomarker for aggressive periodontitis","authors":"T. Pereira, G. Salunkhe, A. Anjali, Sheetal S Choudhari, Rishikesh Mehta, Apeksha Jain","doi":"10.4103/jmau.jmau_107_22","DOIUrl":"https://doi.org/10.4103/jmau.jmau_107_22","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70799646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autofluorescence in flow cytometry: A diagnostic conundrum secondary to drugs","authors":"M. Kotru, Shilpi More, Malvika Shastri, Monica Gupta","doi":"10.4103/jmau.jmau_117_22","DOIUrl":"https://doi.org/10.4103/jmau.jmau_117_22","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70800283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lipoma of the fallopian tube with sebaceous metaplasia of the uterine cervix – Incidental or Pathological – Documentation of a rare case report","authors":"Ayeesha Thajudeen, A. Kannan, Vijayashree Raghavan, M. Mahadaven","doi":"10.4103/jmau.jmau_10_23","DOIUrl":"https://doi.org/10.4103/jmau.jmau_10_23","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70799774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Placental teratoma: A case report of an unusual entity","authors":"P. Diwaker, Malvika Shastri, D. Bansal, P. Gogoi","doi":"10.4103/jmau.jmau_116_22","DOIUrl":"https://doi.org/10.4103/jmau.jmau_116_22","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70800274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The protective effect of selenium versus ascorbic acid on potassium dichromate-induced thyroid toxicity in adult male albino rats","authors":"AbeerA Rahman, Hanan Belal, SaharGalal Gouda, Somaya Hosny","doi":"10.4103/jmau.jmau_41_23","DOIUrl":"https://doi.org/10.4103/jmau.jmau_41_23","url":null,"abstract":"","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135318943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Possible Effects of Vitamin D3 on AlCl₃-Induced Histological and Morphometric Alterations of Adult Male Albino Rat Hippocampus.","authors":"Jana Kamel Bashraheel,&nbsp;Zienab A Alrefaie,&nbsp;Hossam Eldin Ahmed Awad Hammad,&nbsp;Soad Shaker Ali","doi":"10.4103/jmau.jmau_42_21","DOIUrl":"https://doi.org/10.4103/jmau.jmau_42_21","url":null,"abstract":"<p><strong>Context: </strong>Alzheimer's disease (AD) is a challenging neurodegenerative disease, and Vitamin D was proved to have neuroprotective effects.</p><p><strong>Aim: </strong>This study was conducted to evaluate the potential neuroprotective effects of Vitamin D3 supplementation on AlCl₃-induced AD rat model in different hippocampal subregions (CA1, CA2, and CA3). It also aimed to compare the protective effects of protective versus therapeutic effects of Vitamin D3 regiments on the number of degenerated neurons and the neuronal layer thickness.</p><p><strong>Materials and methods: </strong>Twenty-four adult male Albino Wister rats were sorted into GI: control; GII: AlCl₃-AD model (100 mg/kg) orally for 42 days; GIII: Rats were co-treated with AlCl₃ (as GII) and Vitamin D₃ (400 IU/kg/day) orally for 42 days; GIV: Rats were treated with AlCl₃ for 42 days then with Vitamin D₃ for further 2 weeks. Sagittal sections (5 μ) from paraffin-processed brains previously fixed in 10% neutral-buffered formalin were stained with hematoxylin and eosin to evaluate the thickness and number of degenerated neurons in the hippocampal CA1, CA2, and CA3 subregions.</p><p><strong>Statistical analysis: </strong>The results of this study were expressed as mean ± standard deviation and analyzed by using IBM SPSS Statistics for Windows, version 23 (IBM SPSS, IBM Corp., Armonk, N.Y., USA). <i>P</i> < 0.05 was considered statistically significant.</p><p><strong>Results: </strong>Vitamin D₃ supplementations modulated the degenerative changes observed in the hippocampus of AD rat model. In all hippocampal subregions, the thickness was higher in rats treated with Vitamin D₃ after the AD induction than rats treated with Vitamin D₃ during AD induction. However, this increase was only significant in CA2. Comparison of the number of degenerated neurons between both groups treated with Vitamin D₃ revealed that in CA1, the number of degenerated neurons did not statistically differ between the two groups. However, it was insignificantly lower in CA2 in rats treated with Vitamin D₃ after the AD induction, and in CA3, it was insignificantly lower in rats treated with Vitamin D₃ during the AD induction.</p><p><strong>Conclusions: </strong>Vitamin D₃ was found to be effective in ameliorating histological and morphometric alterations in AlCl₃-induced AD in rat model and could be proposed as both preventive and therapeutic supplements in high-risk AD patients.</p>","PeriodicalId":16340,"journal":{"name":"Journal of Microscopy and Ultrastructure","volume":"11 1","pages":"52-59"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2a/04/JMAU-11-52.PMC10153740.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9767802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}