Electroanalysis最新文献

{"title":"Cutting-Edge Applications of Titanium Dioxide in Biosensors","authors":"Ehsan Sanattalab,&nbsp;Dilek Kanarya,&nbsp;Aliakbar Ebrahimi,&nbsp;Reza Didarian,&nbsp;Fatma Doğan Güzel,&nbsp;Nimet Yıldırım Tirgil","doi":"10.1002/elan.70049","DOIUrl":"10.1002/elan.70049","url":null,"abstract":"<p>Titanium dioxide (TiO₂)-based nanocomposites have attracted increasing attention as functional materials for biosensor applications due to their high surface area, biocompatibility, photocatalytic activity, and electron transfer capabilities. These features significantly enhance the sensitivity, specificity, and stability of biosensors across various platforms. This review presents a comprehensive overview of recent advancements in TiO₂-based biosensors, with a focus on three major detection strategies: electrochemical, optical, and electrochemiluminescence (ECL) methods. In the electrochemical domain, TiO₂ nanomaterials have been used to develop sensors capable of detecting analytes such as acrylamide with high sensitivity and fast response times. Optical techniques, including surface plasmon resonance (SPR), have used TiO₂ nanostructures to improve detection of cancer biomarkers such as hepatocellular carcinoma antigens. ECL-based systems utilizing TiO₂ composites show enhanced emission intensity and low detection limits due to improved electron transport properties. Furthermore, the integration of TiO₂ with other nanomaterials—such as silver nanoparticles, graphene quantum dots, and titanium-based hybrids—has led to multifunctional sensing platforms with superior analytical performance. This review also discusses the role of TiO₂ in detecting clinically relevant targets, including carcinoembryonic antigen (CEA), highlighting its utility in early diagnosis, food safety, and environmental monitoring. TiO₂ nanomaterials offer strong potential for next-generation biosensors and point-of-care diagnostic devices due to their versatility, performance, and cost-effectiveness.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 9","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144998844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sensitive Detection of Hesperidin Based on CN-MWCNTs/Ti3C2 Composite Modified Electrode","authors":"Wei Liu,&nbsp;Yanhua Sun,&nbsp;Songfeng Yin,&nbsp;Hao Li,&nbsp;Miao Yang,&nbsp;Pingping Huang,&nbsp;Zi Li,&nbsp;Nannan Wang,&nbsp;Deming Li","doi":"10.1002/elan.70046","DOIUrl":"10.1002/elan.70046","url":null,"abstract":"<p>In this study, carbon nitride-multiwalled carbon nanotubes/ MXenes (CN-MWCNTs/Ti₃C₂) nanocomposites with excellent properties were synthesized by a convenient method and characterized using various methods. By modifying the CN-MWCNTs/Ti₃C₂ composites on glassy carbon electrode, an electrochemical sensor capable of sensitive and rapid detection of hesperidin (HPD) was established. Under the optimal conditions, the sensor showed excellent detection performance for HPD (0.1 M PBS (pH 7.0)). The linear range was 0.05–503 μM, and the detection limit (S/N = 3) was 0.017 μM. In addition, the sensor has the advantages of good immunity to interference, stability and reproducibility.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 9","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144998997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sensitive Detection of Hesperidin Based on CN-MWCNTs/Ti3C2 Composite Modified Electrode","authors":"Wei Liu,&nbsp;Yanhua Sun,&nbsp;Songfeng Yin,&nbsp;Hao Li,&nbsp;Miao Yang,&nbsp;Pingping Huang,&nbsp;Zi Li,&nbsp;Nannan Wang,&nbsp;Deming Li","doi":"10.1002/elan.70046","DOIUrl":"10.1002/elan.70046","url":null,"abstract":"<p>In this study, carbon nitride-multiwalled carbon nanotubes/ MXenes (CN-MWCNTs/Ti₃C₂) nanocomposites with excellent properties were synthesized by a convenient method and characterized using various methods. By modifying the CN-MWCNTs/Ti₃C₂ composites on glassy carbon electrode, an electrochemical sensor capable of sensitive and rapid detection of hesperidin (HPD) was established. Under the optimal conditions, the sensor showed excellent detection performance for HPD (0.1 M PBS (pH 7.0)). The linear range was 0.05–503 μM, and the detection limit (S/N = 3) was 0.017 μM. In addition, the sensor has the advantages of good immunity to interference, stability and reproducibility.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 9","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144998882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasensitive and Fast Determination of Fulvic Acid in Sapropel and in the Techirghiol Lake Water","authors":"Andreea Elena Sandu Dorneanu,&nbsp;Raluca-Ioana Stefan- van Staden,&nbsp;Damaris-Cristina Gheorghe","doi":"10.1002/elan.70050","DOIUrl":"10.1002/elan.70050","url":null,"abstract":"<p>Sapropel and Techirghiol Lake water are an excellent source of organic substances like fulvic acid, which can be extracted and used in the pharmaceutical industry. On-site determination of fulvic acid from lake water and sapropel is valuable for the possibility of exploring the sapropel and water as it is (can serve as daily quality control) for therapeutic purposes, or it can be taken to specialised laboratories for the extraction of fulvic acid, followed by its utilisation in the pharmaceutical industry. An ultrasensitive stochastic sensor based on reduced graphene oxide paste decorated with gold and palladium nanoparticles and modified with quinine was designed, characterised, and validated for the determination of fulvic acid in sapropel and also in the Techirghiol Lake water. The sensor can be used on a wide concentration range, from 5.00 fg mL⁻¹ to 5.00 μg mL⁻¹, with a high sensitivity (1.97 × 10⁸s⁻¹ g⁻¹ mL). High recovery values (&gt;99.00%) were recorded for the determination of fulvic acid in sapropel and in the Techirghiol Lake water. Validation of the proposed sensor and screening method for fulvic acid is done versus an HPLC method. The on-site measurements with the ultrasensitive stochastic sensor will contribute to the reliable determination of the quality of sapropel and water in real time.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 9","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144998996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Appropriate Acid Etching to Obtain Defect-Rich and Porous Zeolitic-Imidazolate-Framework-Derived Undercoordinated Fe-NC Catalysts Toward Boosted Oxygen Reduction Reaction","authors":"Jiahong Zeng,&nbsp;Wenbin Ma,&nbsp;Yanming Li,&nbsp;Yi Wang,&nbsp;Lan Wang","doi":"10.1002/elan.70044","DOIUrl":"10.1002/elan.70044","url":null,"abstract":"<p>Iron-nitrogen-carbon (Fe-NC) catalysts, particularly those with Fe-N₄ coordination moieties, are the most promising alternatives to commercial Pt@C for oxygen reduction reaction (ORR) in green energy conversion. The acid etching strategy is an effective and simple strategy to break the symmetric coordination of Fe-N₄ on the carbon substrate to further enhance the activity. Herein, a superior Fe-NC catalyst with undercoordinated Fe-N₂ moieties was produced through a concentration-controlled acid etching strategy, following an underlying quantitative indicator (I_D/I_G) to regulate its defect degree accurately. Due to the defect-rich and porous carbon structure to accelerate the mass transfer, this Fe-N₂ catalyst exhibited an admirable half-wave potential (E_1/2) of 0.85 V_RHE versus 0.87 V_RHE for commercial Pt@C, and a better stability and a higher limiting current density (−6.3 mA cm⁻²) in alkaline conditions, outperforming the other involved Fe-NCs and the Pt@C. This work provides an acid etching strategy to accurately control the defect degree and break the symmetrical Fe-N₄ coordination structure of Fe-NCs for enhancing the ORR activity.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 9","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144923457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial for Special Issue on Electrochemical Sensors for Non-Invasive Health Monitoring","authors":"Ming Zhou","doi":"10.1002/elan.70042","DOIUrl":"https://doi.org/10.1002/elan.70042","url":null,"abstract":"<p>Electrochemical sensors have emerged as a pivotal technology in the realm of noninvasive health monitoring. The human body is a complex system, where dynamic tracking of biochemical processes can provide valuable insights and feedback for improving health and understanding underlying biological functions. Electrochemical and electroanalytical techniques stand out due to their ability to offer continuous real-time monitoring, high sensitivity in both <i>in-vivo</i> and <i>in-vitro</i> environments, and seamless integration with modern miniaturized electronics suitable for portable, wearable, or implantable devices.</p><p>Despite these advances, the quest for expanding the use of electrochemical sensors to improve human health necessitates a focus on noninvasive monitoring methods. To achieve this, several factors require attention and enhancement, including novel transducer designs, surface modification methods, electrode reaction kinetics in biological matrices, biocompatibility, biofouling prevention, system integration, data processing techniques, multimodal sensing, and the correlation between sensing data and diseases.</p><p>This special issue aims to present a curated collection of the latest advancements in electrochemical sensors for non-invasive health monitoring. Our goal is to provide insights into current research, foster new synergies, and outline future directions for developing next-generation electrochemical systems that can significantly contribute to enhancing life and health.</p><p>The issue encompasses a diverse range of topics, reflecting the multifaceted nature of this rapidly evolving field:</p><p>This special issue features contributions ranging from fundamental research articles to insightful reviews and brief communications, each providing unique perspectives on the state-of-the-art in electrochemical sensors for noninvasive health monitoring. These works collectively highlight the importance of continued innovation and interdisciplinary collaboration in this field.</p><p>I extend our sincere gratitude to all authors for their exceptional contributions and to the reviewers for their critical and constructive feedback. Their efforts have ensured the high quality of this issue. I hope that the articles presented here will inspire further research and technological advancements, ultimately leading to more effective health monitoring solutions and an improved quality of life. I also express my gratitude to the five guest editors listed below for their unwavering commitment, profound expertise, and indispensable contributions, which have been instrumental in molding this special issue into a comprehensive and enlightening compendium for both researchers and practitioners.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 9","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/epdf/10.1002/elan.70042","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144923459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial for Special Issue on Electrochemical Sensors for Non-Invasive Health Monitoring","authors":"Ming Zhou","doi":"10.1002/elan.70042","DOIUrl":"10.1002/elan.70042","url":null,"abstract":"<p>Electrochemical sensors have emerged as a pivotal technology in the realm of noninvasive health monitoring. The human body is a complex system, where dynamic tracking of biochemical processes can provide valuable insights and feedback for improving health and understanding underlying biological functions. Electrochemical and electroanalytical techniques stand out due to their ability to offer continuous real-time monitoring, high sensitivity in both <i>in-vivo</i> and <i>in-vitro</i> environments, and seamless integration with modern miniaturized electronics suitable for portable, wearable, or implantable devices.</p><p>Despite these advances, the quest for expanding the use of electrochemical sensors to improve human health necessitates a focus on noninvasive monitoring methods. To achieve this, several factors require attention and enhancement, including novel transducer designs, surface modification methods, electrode reaction kinetics in biological matrices, biocompatibility, biofouling prevention, system integration, data processing techniques, multimodal sensing, and the correlation between sensing data and diseases.</p><p>This special issue aims to present a curated collection of the latest advancements in electrochemical sensors for non-invasive health monitoring. Our goal is to provide insights into current research, foster new synergies, and outline future directions for developing next-generation electrochemical systems that can significantly contribute to enhancing life and health.</p><p>The issue encompasses a diverse range of topics, reflecting the multifaceted nature of this rapidly evolving field:</p><p>This special issue features contributions ranging from fundamental research articles to insightful reviews and brief communications, each providing unique perspectives on the state-of-the-art in electrochemical sensors for noninvasive health monitoring. These works collectively highlight the importance of continued innovation and interdisciplinary collaboration in this field.</p><p>I extend our sincere gratitude to all authors for their exceptional contributions and to the reviewers for their critical and constructive feedback. Their efforts have ensured the high quality of this issue. I hope that the articles presented here will inspire further research and technological advancements, ultimately leading to more effective health monitoring solutions and an improved quality of life. I also express my gratitude to the five guest editors listed below for their unwavering commitment, profound expertise, and indispensable contributions, which have been instrumental in molding this special issue into a comprehensive and enlightening compendium for both researchers and practitioners.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 9","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/epdf/10.1002/elan.70042","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144923456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Appropriate Acid Etching to Obtain Defect-Rich and Porous Zeolitic-Imidazolate-Framework-Derived Undercoordinated Fe-NC Catalysts Toward Boosted Oxygen Reduction Reaction","authors":"Jiahong Zeng,&nbsp;Wenbin Ma,&nbsp;Yanming Li,&nbsp;Yi Wang,&nbsp;Lan Wang","doi":"10.1002/elan.70044","DOIUrl":"https://doi.org/10.1002/elan.70044","url":null,"abstract":"<p>Iron-nitrogen-carbon (Fe-NC) catalysts, particularly those with Fe-N₄ coordination moieties, are the most promising alternatives to commercial Pt@C for oxygen reduction reaction (ORR) in green energy conversion. The acid etching strategy is an effective and simple strategy to break the symmetric coordination of Fe-N₄ on the carbon substrate to further enhance the activity. Herein, a superior Fe-NC catalyst with undercoordinated Fe-N₂ moieties was produced through a concentration-controlled acid etching strategy, following an underlying quantitative indicator (I_D/I_G) to regulate its defect degree accurately. Due to the defect-rich and porous carbon structure to accelerate the mass transfer, this Fe-N₂ catalyst exhibited an admirable half-wave potential (E_1/2) of 0.85 V_RHE versus 0.87 V_RHE for commercial Pt@C, and a better stability and a higher limiting current density (−6.3 mA cm⁻²) in alkaline conditions, outperforming the other involved Fe-NCs and the Pt@C. This work provides an acid etching strategy to accurately control the defect degree and break the symmetrical Fe-N₄ coordination structure of Fe-NCs for enhancing the ORR activity.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 9","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144923458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cover Picture: (Electroanalysis 9/2025)","authors":"","doi":"10.1002/elan.70057","DOIUrl":"https://doi.org/10.1002/elan.70057","url":null,"abstract":"<p>Cover picture provided by Dr. Elena Benito-Peña and Dr. Susana Campuzano. <i>Electroanalysis</i> covers all branches of electroanalytical chemistry, including both fundamental and application papers as well as reviews dealing with analytical voltammetry, potentiometry, new electrochemical sensors and detection schemes, nanoscale electrochemistry, advanced electromaterials, nanobioelectronics, point-of-care diagnostics, wearable sensors, and practical applications.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 9","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/epdf/10.1002/elan.70057","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144910472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cover Picture: (Electroanalysis 9/2025)","authors":"","doi":"10.1002/elan.70057","DOIUrl":"10.1002/elan.70057","url":null,"abstract":"<p>Cover picture provided by Dr. Elena Benito-Peña and Dr. Susana Campuzano. <i>Electroanalysis</i> covers all branches of electroanalytical chemistry, including both fundamental and application papers as well as reviews dealing with analytical voltammetry, potentiometry, new electrochemical sensors and detection schemes, nanoscale electrochemistry, advanced electromaterials, nanobioelectronics, point-of-care diagnostics, wearable sensors, and practical applications.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 9","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/epdf/10.1002/elan.70057","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144910471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}