Electroanalysis最新文献

{"title":"Aptamer-Based Electrochemical Point-of-Care Tests: Signal Design to Clinical Readiness","authors":"Xingxing Li,&nbsp;Li Fu,&nbsp;Fei Chen,&nbsp;Yanfei Lv,&nbsp;Shichao Zhao,&nbsp;Hassan Karimi-Maleh","doi":"10.1002/elan.70116","DOIUrl":"https://doi.org/10.1002/elan.70116","url":null,"abstract":"<p>Aptamer-based electrochemical biosensors have emerged as powerful platforms for point-of-care diagnostics by combining the molecular recognition precision of nucleic acid aptamers with the rapid and portable nature of electrochemical detection. This review critically examines how electrochemical signal-transduction strategies translate aptamer–target interactions into measurable outputs and assesses their readiness for clinical implementation. Diverse signal designs are analyzed with respect to sensitivity, reproducibility, and suitability for miniaturized, reagent-free testing. Representative applications in infectious-disease diagnosis, cancer biomarker detection, cardiac and metabolic monitoring, and therapeutic drug measurement demonstrate that aptamer sensors can match or surpass current laboratory assays in analytical performance. Nevertheless, challenges remain in achieving stability in biological matrices, mitigating surface fouling, and ensuring large-scale manufacturing and regulatory validation. Advances in chemical modifications, antifouling surface engineering, and flexible device architectures, including wearable and implantable formats, are progressively overcoming these barriers. The review also contrasts aptamers with antibodies to highlight niches where aptamer sensors provide unique advantages, such as continuous in vivo monitoring and rapid adaptation to emerging biomarkers. Overall, electrochemical aptamer sensors are approaching a transformative threshold from laboratory innovation to practical clinical diagnostics, marking a critical intersection between biotechnology and electronic sensing that may redefine the future of personalized and decentralized healthcare.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"38 3","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147562654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High Performance Pt-Os/TiO2/GO Photoelectrocatalyst for Methanol Oxidation in Acidic Media","authors":"Shakir Aadi Harbi,&nbsp;Behjat Deiminiat,&nbsp;Mahdi Ozgoli,&nbsp;Gholam Hossein Rounaghi","doi":"10.1002/elan.70109","DOIUrl":"10.1002/elan.70109","url":null,"abstract":"<p>Herein, we report the preparation of a new and highly efficient photoelectrocatalyst for electrocatalitic oxidation of methanol in acidic media. To this end, a fluorine-tin oxide (FTO) electrode derived from commercial FTO plates was modified layer by layer with graphene oxide (GO) and titanium dioxide (TiO₂), and decorated with platinum-osmium nanoparticles (Pt-OsNPs) through co-electrodeposition technique. GO nanosheets and TiO₂ nanoparticles not only served as signal amplifier and photoactive material, respectively, but also, they provided a high surface area for electrodeposition of Pt-OsNPs. The scanning electron microscopy (SEM) images and energy dispersive X-ray spectroscopy (EDS) spectra revealed the change of the FTO surface in each modification step. The photo electrocatalytic activity of Pt-Os/TiO₂/GO/FTO for methanol oxidation was assessed under visible light irradiation, and an anodic peak current density of about 10 mA cm⁻² was obtained at 0.75 V. The chronoamperometry measurements showed the improved durability of Pt-Os/TiO₂/GO/FTO photocatalyst compared to other studied catalysts including Pt/FTO, Pt/GO/FTO, and Pt/TiO₂/GO/FTO. The values of exchange current density (<i>J</i>₀) obtained from Tofel plots for studied catalysts indicted that the methanol oxidation reaction is less limited kinetically in the presence of Pt-Os/TiO₂/GO/FTO photocatalyst.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"38 2","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147568825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High Performance Pt-Os/TiO2/GO Photoelectrocatalyst for Methanol Oxidation in Acidic Media","authors":"Shakir Aadi Harbi,&nbsp;Behjat Deiminiat,&nbsp;Mahdi Ozgoli,&nbsp;Gholam Hossein Rounaghi","doi":"10.1002/elan.70109","DOIUrl":"10.1002/elan.70109","url":null,"abstract":"<p>Herein, we report the preparation of a new and highly efficient photoelectrocatalyst for electrocatalitic oxidation of methanol in acidic media. To this end, a fluorine-tin oxide (FTO) electrode derived from commercial FTO plates was modified layer by layer with graphene oxide (GO) and titanium dioxide (TiO₂), and decorated with platinum-osmium nanoparticles (Pt-OsNPs) through co-electrodeposition technique. GO nanosheets and TiO₂ nanoparticles not only served as signal amplifier and photoactive material, respectively, but also, they provided a high surface area for electrodeposition of Pt-OsNPs. The scanning electron microscopy (SEM) images and energy dispersive X-ray spectroscopy (EDS) spectra revealed the change of the FTO surface in each modification step. The photo electrocatalytic activity of Pt-Os/TiO₂/GO/FTO for methanol oxidation was assessed under visible light irradiation, and an anodic peak current density of about 10 mA cm⁻² was obtained at 0.75 V. The chronoamperometry measurements showed the improved durability of Pt-Os/TiO₂/GO/FTO photocatalyst compared to other studied catalysts including Pt/FTO, Pt/GO/FTO, and Pt/TiO₂/GO/FTO. The values of exchange current density (<i>J</i>₀) obtained from Tofel plots for studied catalysts indicted that the methanol oxidation reaction is less limited kinetically in the presence of Pt-Os/TiO₂/GO/FTO photocatalyst.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"38 2","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147568833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High Performance Pt-Os/TiO2/GO Photoelectrocatalyst for Methanol Oxidation in Acidic Media","authors":"Shakir Aadi Harbi,&nbsp;Behjat Deiminiat,&nbsp;Mahdi Ozgoli,&nbsp;Gholam Hossein Rounaghi","doi":"10.1002/elan.70109","DOIUrl":"10.1002/elan.70109","url":null,"abstract":"<p>Herein, we report the preparation of a new and highly efficient photoelectrocatalyst for electrocatalitic oxidation of methanol in acidic media. To this end, a fluorine-tin oxide (FTO) electrode derived from commercial FTO plates was modified layer by layer with graphene oxide (GO) and titanium dioxide (TiO₂), and decorated with platinum-osmium nanoparticles (Pt-OsNPs) through co-electrodeposition technique. GO nanosheets and TiO₂ nanoparticles not only served as signal amplifier and photoactive material, respectively, but also, they provided a high surface area for electrodeposition of Pt-OsNPs. The scanning electron microscopy (SEM) images and energy dispersive X-ray spectroscopy (EDS) spectra revealed the change of the FTO surface in each modification step. The photo electrocatalytic activity of Pt-Os/TiO₂/GO/FTO for methanol oxidation was assessed under visible light irradiation, and an anodic peak current density of about 10 mA cm⁻² was obtained at 0.75 V. The chronoamperometry measurements showed the improved durability of Pt-Os/TiO₂/GO/FTO photocatalyst compared to other studied catalysts including Pt/FTO, Pt/GO/FTO, and Pt/TiO₂/GO/FTO. The values of exchange current density (<i>J</i>₀) obtained from Tofel plots for studied catalysts indicted that the methanol oxidation reaction is less limited kinetically in the presence of Pt-Os/TiO₂/GO/FTO photocatalyst.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"38 2","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147569109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Situ Electrochemical Reconstruction of CoOOH@FeOOH Heterostructure for High-Power-Density Zn-Air Batteries","authors":"Haixu Wang,&nbsp;Tingwei Zhang,&nbsp;Zhen Sun,&nbsp;Xiaonan Qi,&nbsp;Rongsong cao,&nbsp;Chuanlai Jiao","doi":"10.1002/elan.70115","DOIUrl":"10.1002/elan.70115","url":null,"abstract":"<p>Efficient bifunctional electrocatalysts are crucial for the advancement of rechargeable zinc-air batteries (ZABs). In this article, we successfully synthesized a high-performance catalyst R-CoOOH@FeOOH through the oxygen evolution reaction (OER). Additionally, in situ Raman characterization results indicate that CoFe@NC-w undergo electrochemical reconstruction during the OER, leading to the formation of CoOOH and FeOOH species. This dynamic structural evolution is responsible for the enhanced OER activity of the catalyst. This transformation endowed the catalyst with exceptional OER activity. In addition, the catalyst exhibited exceptional performance in the oxygen reduction reaction, which shows a half-wave potential of 0.86 V vs. (RHE) reversible hydrogen electrode. When integrated into a ZAB, the catalyst delivers a low charging potential of 2.3 V at a high current density of 50 mA cm⁻², accompanied by an excellent long-term durability of 600 h. These findings offer viable strategies for the development of high-performance catalysts for ZAB.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"38 2","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147569110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Situ Electrochemical Reconstruction of CoOOH@FeOOH Heterostructure for High-Power-Density Zn-Air Batteries","authors":"Haixu Wang,&nbsp;Tingwei Zhang,&nbsp;Zhen Sun,&nbsp;Xiaonan Qi,&nbsp;Rongsong cao,&nbsp;Chuanlai Jiao","doi":"10.1002/elan.70115","DOIUrl":"https://doi.org/10.1002/elan.70115","url":null,"abstract":"<p>Efficient bifunctional electrocatalysts are crucial for the advancement of rechargeable zinc-air batteries (ZABs). In this article, we successfully synthesized a high-performance catalyst R-CoOOH@FeOOH through the oxygen evolution reaction (OER). Additionally, in situ Raman characterization results indicate that CoFe@NC-w undergo electrochemical reconstruction during the OER, leading to the formation of CoOOH and FeOOH species. This dynamic structural evolution is responsible for the enhanced OER activity of the catalyst. This transformation endowed the catalyst with exceptional OER activity. In addition, the catalyst exhibited exceptional performance in the oxygen reduction reaction, which shows a half-wave potential of 0.86 V vs. (RHE) reversible hydrogen electrode. When integrated into a ZAB, the catalyst delivers a low charging potential of 2.3 V at a high current density of 50 mA cm⁻², accompanied by an excellent long-term durability of 600 h. These findings offer viable strategies for the development of high-performance catalysts for ZAB.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"38 2","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147568834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Situ Electrochemical Reconstruction of CoOOH@FeOOH Heterostructure for High-Power-Density Zn-Air Batteries","authors":"Haixu Wang,&nbsp;Tingwei Zhang,&nbsp;Zhen Sun,&nbsp;Xiaonan Qi,&nbsp;Rongsong cao,&nbsp;Chuanlai Jiao","doi":"10.1002/elan.70115","DOIUrl":"10.1002/elan.70115","url":null,"abstract":"<p>Efficient bifunctional electrocatalysts are crucial for the advancement of rechargeable zinc-air batteries (ZABs). In this article, we successfully synthesized a high-performance catalyst R-CoOOH@FeOOH through the oxygen evolution reaction (OER). Additionally, in situ Raman characterization results indicate that CoFe@NC-w undergo electrochemical reconstruction during the OER, leading to the formation of CoOOH and FeOOH species. This dynamic structural evolution is responsible for the enhanced OER activity of the catalyst. This transformation endowed the catalyst with exceptional OER activity. In addition, the catalyst exhibited exceptional performance in the oxygen reduction reaction, which shows a half-wave potential of 0.86 V vs. (RHE) reversible hydrogen electrode. When integrated into a ZAB, the catalyst delivers a low charging potential of 2.3 V at a high current density of 50 mA cm⁻², accompanied by an excellent long-term durability of 600 h. These findings offer viable strategies for the development of high-performance catalysts for ZAB.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"38 2","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147568826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electroanalytical Quantification of Zn2+ and Cd2+ in Aqueous Matrices Using Low-Cost Cork Electrodes via Anodic Stripping Voltammetry","authors":"Artejose Revoredo da Silva,&nbsp;Karen Giovanna Duarte Magalhaes,&nbsp;Thalita Medeiros Barros,&nbsp;José Eudes Lima Santos,&nbsp;Carlos A. Martínez-Huitle,&nbsp;Elisama Vieira dos Santos","doi":"10.1002/elan.70114","DOIUrl":"10.1002/elan.70114","url":null,"abstract":"<p>In recent years, the development of industries has grown a lot with the increase in population and, consequently, a global concern about environmental pollution, especially by highly dangerous pollutants such as heavy metal ions. Among these potentially toxic metals are Zn²⁺ and Cd²⁺. In human health, small amounts of Zn²⁺ are essential for proper metabolic functioning, while excessively high concentrations will negatively affect the body's functioning. Cd²⁺, even in low concentrations, is highly toxic. This concern is particularly relevant in effluents from the oil industry, where the significant presence of organic and inorganic substances, with diverse compositions, can represent a considerable environmental challenge. Therefore, the aim of this work was to investigate the use of 50% (m/m) graphite/cork electrodes to quantify Zn²⁺ and Cd²⁺ ions in real samples of tap water, groundwater and produced water, using differential pulse anodic stripping voltammetry (DPASV) as an electroanalytical tool. The results obtained clearly showed that the application of this electrode was efficient in detecting the heavy metal ions Zn²⁺ and Cd²⁺, with a detection limit of 0.095 µg L⁻¹ and quantification limit of 0.317 µg L⁻¹ for Zn²⁺ and a detection limit of 56 µg L⁻¹ and quantification limit of 120 µg L⁻¹ for Cd²⁺. In the water recovery tests, the results for Zn²⁺ and Cd²⁺ ions were within the acceptable range (105%–118%), which suggests that the proposed methodology is reliable. In general, this approach highlights the ease of producing the electrode with low-cost materials, the good sensitivity of the electrochemical method, the low consumption of reagents and the rate of analysis, thus contributing to another electroanalytical approach for monitoring the heavy metal ions (Zn²⁺ and Cd²⁺)in real effluents.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"38 2","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/epdf/10.1002/elan.70114","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147288464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fluorinated Carboxylate-Based Electrolyte Facilitates Interfacial Film Formation and Desolvation of Low-Temperature Lithium Metal Batteries","authors":"Shibing Wang,&nbsp;Jie Wang,&nbsp;Xue Kong,&nbsp;Xuhui Zheng,&nbsp;Yanli Ruan","doi":"10.1002/elan.70103","DOIUrl":"10.1002/elan.70103","url":null,"abstract":"<p>The electrochemical performance of lithium metal batteries hinges on interfacial desolvation and ion transport kinetics, particularly in low-temperature environments. Herein, we design a fluorinated carboxylate electrolyte that facilitates desolvation and promotes the formation of interfacial films for low-temperature lithium metal batteries. By employing lithium bis(fluorosulfonyl)imide (LiFSI) as the lithium salt and using methyl trifluoroacetate (MTFA) and fluoroethylene carbonate (FEC) as solvents, an MTFA-FEC fluorinated carboxylate-based electrolyte is formulated. MTFA effectively reduces the freezing point of the electrolyte, while FEC enhances the dissociation of LiFSI and improves the film-forming ability of the electrolyte. The relatively weak binding force between Li⁺ and MTFA is conducive to the desolvation process. By adjusting the ratio of MTFA and FEC solvents, we effectively enhance the stability of the electrode–electrolyte interface. The results demonstrate that when the volume ratio of MTFA to FEC is 8:2, the Li||Cu cell using this electrolyte can stably cycle for 80 cycles at 0°C. At −20°C, the Li||LFP cell can stably cycle for 200 cycles at 0.2 C, with an initial discharge specific capacity of 100.2 mAh g⁻¹. Notably, even at 1 C, the discharge specific capacity remains at 53.0 mAh g⁻¹.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"38 2","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147320930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Direct Electrochemical Detection of Glyphosate at Organosilane Functionalized Synthetic Saponite Modified Electrode","authors":"Anselme Junior Tagne,&nbsp;Liva Dzene,&nbsp;Laure Michelin,&nbsp;Ludovic Josien,&nbsp;Séverinne Rigolet,&nbsp;Gustave Kenne Dedzo,&nbsp;Emmanuel Ngameni","doi":"10.1002/elan.70110","DOIUrl":"10.1002/elan.70110","url":null,"abstract":"<p>Considering the environmental and health issues caused by glyphosate, a controversial nonselective herbicide widely used, the development of reliable quantification methods to monitor the concentration of this compound in natural environments is of critical importance. In this work, a carbon paste electrode modified by functionalized saponite clay mineral was applied for the first time for the direct quantification of glyphosate. The grafting of the organophilic cationic silane (dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride) was promoted by the highly charged synthetic saponite layers. The characterizations of the organohybrid saponite by Fourier transformed IR (FTIR) and solid state ²⁹Si NMR spectroscopies confirmed the grafting of the silane while X-ray diffraction (XRD) analysis revealed the non-intercalation of the silane in the interlayer space. This surface functionalization resulted in minor modification of the morphology of the saponite particles as observed on the scanning electron microscope (SEM) images. When the functionalized saponite was used as the electrode modifier, the presence of silane increased the glyphosate signal intensity while decreasing the peak potential, certainly through favorable organophilic and electrostatic interactions between the functionalized clay mineral and the negatively charged pesticide. Under optimal experimental conditions (7 %wt in carbon paste and pH of the solution of 8) and for glyphosate concentrations in the range 5 to 60 µM, a detection limit of 0.12 µM was obtained. Excepted for Cu²⁺, which strongly interferes with the glyphosate signal, the other chemical species investigated (Al³⁺, Ca²⁺, Mg²⁺, and paraquat) poorly affect the pesticide detection. Furthermore, this sensor was successfully applied for the quantification of glyphosate in well water, with a recovery higher than 95%.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"38 2","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147320909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}