Electroanalysis最新文献_第3页

Green Solid-State Potentiometric Platform for Vonoprazan Fumarate Determination in Pharmaceutical Dosage Form and Spiked Human Plasma

IF 2.7 3区化学

Electroanalysis Pub Date : 2025-02-25 DOI: 10.1002/elan.12035

Maha M. Abou El-Alamin, Dina A. Mohamed, Amir S. Farag

{"title":"Green Solid-State Potentiometric Platform for Vonoprazan Fumarate Determination in Pharmaceutical Dosage Form and Spiked Human Plasma","authors":"Maha M. Abou El-Alamin, Dina A. Mohamed, Amir S. Farag","doi":"10.1002/elan.12035","DOIUrl":"https://doi.org/10.1002/elan.12035","url":null,"abstract":"Vonoprazan fumarate (VPZ), a potent potassium-competitive acid blocker, has gained prominence recently for its efficacy in acid-related disorders, surpassing traditional proton pump inhibitors in acid suppression. Combining molecular modeling simulations with electrochemical sensors represents a cutting-edge approach in analytical chemistry. Molecular docking guided the selection of calix[8]arene as the optimal ionophore due to its superior affinity for VPZ, supported by robust docking scores and hydrophobic interactions. The final sensor configuration, incorporating calix[8]arene, sodium tetraphenylborate, and dioctyl phthalate, exhibited outstanding electroanalytical characteristics, including improved slope, enhanced potential stability, and rapid response times. Notably, the developed solid-contact sensors demonstrated a Nernstian response with a slope of 58.587 over a concentration range of 1 × 10−8–1 × 10−2 M, achieving an impressive low detection limit of 3.09 × 10−9 M. The developed method offers a cost-effective and environmentally sustainable solution for precise monitoring of VPZ, promising significant advancements in pharmaceutical quality control.","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143481486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Metal Electrode and Concentration Redox Couple Effect on Electrical Circuit Parameters for Heterocharge System: Potential Application for Lithium-Ion Battery

IF 2.7 3区化学

Electroanalysis Pub Date : 2025-02-20 DOI: 10.1002/elan.12024

Farid Taherkhani

{"title":"Effect of Metal Electrode and Concentration Redox Couple Effect on Electrical Circuit Parameters for Heterocharge System: Potential Application for Lithium-Ion Battery","authors":"Farid Taherkhani","doi":"10.1002/elan.12024","DOIUrl":"https://doi.org/10.1002/elan.12024","url":null,"abstract":"The analytical solution has been expanded to describe the circuit parameters of a redox couple with a charge of +1 and 0 for electrochemical reaction in the presence of supporting electrolyte as a potential application in lithium-ion battery. The Gouy–Chapman–Stern theory has been developed to comprehend the capacitance behavior as a function of the difference in electrical potential between the solution and metal parameters (Eeq variable). Finite-element simulations have been employed to explore various electrochemical system configurations, enhancing electrical storage energy by engineering the types of metal electrode and concentration heterocharge redox couple and supporting electrolyte. The initial guess for the Randles circuit parameters has been implemented by Matlab code developing, deriving them from the electrical current response versus time in a frequency-dependent sinusoidal wave function. Subsequently, the optimization problem regarding fitting of the circuit parameters has been performed through open-source Python code for electrochemical impedance spectroscopy using the initial Randles circuit parameter guess. The semianalytical method revealed a minimum in capacitance behavior near the zero value of the Eeq variable. Additionally, the numerical method showed that the capacitance behavior regarding the Eeq variable remains constant for high concentrations of the supporting electrolyte. The charge transfer coefficient demonstrated a monotonic behavior versus Eeq for all electrochemical reactions occurring on the parallel microdisk. A simulation result regarding general trend for capacitance versus Eeq variable is consistent with the available experimental data.","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143455739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Metal Electrode and Concentration Redox Couple Effect on Electrical Circuit Parameters for Heterocharge System: Potential Application for Lithium-Ion Battery

IF 2.7 3区化学

Electroanalysis Pub Date : 2025-02-20 DOI: 10.1002/elan.12024

Farid Taherkhani

{"title":"Effect of Metal Electrode and Concentration Redox Couple Effect on Electrical Circuit Parameters for Heterocharge System: Potential Application for Lithium-Ion Battery","authors":"Farid Taherkhani","doi":"10.1002/elan.12024","DOIUrl":"https://doi.org/10.1002/elan.12024","url":null,"abstract":"The analytical solution has been expanded to describe the circuit parameters of a redox couple with a charge of +1 and 0 for electrochemical reaction in the presence of supporting electrolyte as a potential application in lithium-ion battery. The Gouy–Chapman–Stern theory has been developed to comprehend the capacitance behavior as a function of the difference in electrical potential between the solution and metal parameters (Eeq variable). Finite-element simulations have been employed to explore various electrochemical system configurations, enhancing electrical storage energy by engineering the types of metal electrode and concentration heterocharge redox couple and supporting electrolyte. The initial guess for the Randles circuit parameters has been implemented by Matlab code developing, deriving them from the electrical current response versus time in a frequency-dependent sinusoidal wave function. Subsequently, the optimization problem regarding fitting of the circuit parameters has been performed through open-source Python code for electrochemical impedance spectroscopy using the initial Randles circuit parameter guess. The semianalytical method revealed a minimum in capacitance behavior near the zero value of the Eeq variable. Additionally, the numerical method showed that the capacitance behavior regarding the Eeq variable remains constant for high concentrations of the supporting electrolyte. The charge transfer coefficient demonstrated a monotonic behavior versus Eeq for all electrochemical reactions occurring on the parallel microdisk. A simulation result regarding general trend for capacitance versus Eeq variable is consistent with the available experimental data.","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143455738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rectified Ion Transport with Low-Cost Ionic Diodes Based on Sulfonated Poly-(Phenylene-Oxide)

IF 2.7 3区化学

Electroanalysis Pub Date : 2025-02-19 DOI: 10.1002/elan.12033

Asandiswa Mfenguza, Luthando Tshwenya, Dimpo S. Sipuka, Oluchi V. Nkwachukwu, Keneiloe Khoabane Sikhwivhilu, Frank Marken, Omotayo A. Arotiba

{"title":"Rectified Ion Transport with Low-Cost Ionic Diodes Based on Sulfonated Poly-(Phenylene-Oxide)","authors":"Asandiswa Mfenguza, Luthando Tshwenya, Dimpo S. Sipuka, Oluchi V. Nkwachukwu, Keneiloe Khoabane Sikhwivhilu, Frank Marken, Omotayo A. Arotiba","doi":"10.1002/elan.12033","DOIUrl":"https://doi.org/10.1002/elan.12033","url":null,"abstract":"Ionic rectifiers/diodes are devices with potential applications in water treatment (desalination) and sensors. Diode preparation sometimes involves expensive processes such as laser drilling and thus the need for simpler and low-cost methods. We developed a low-cost cation rectifying hybrid membrane ionic rectifier where a microporous sulfonated poly-(2,6-dimethyl phenylene oxide) (SPPO) was asymmetrically attached to a microhole region in a polypropylene adhesive tape substrate. Contact angle measurements showed that SPPO is hydrophilic with a 62° angle. In comparison, the polypropylene adhesive tape and SPPO within it are hydrophobic with angles of 101° and 87°, respectively, contributing to the diode's stability in water. Zeta potential measurements confirmed the negative charge of the SPPO surface in all electrolyte solutions. Scanning electron microscopy revealed that the punctured tape substrate has a 3–4 µm microhole and a thickness of about 25 µm. The SPPO membrane is ≈29 µm thick with a smooth cross-sectional surface. The effects of electrolyte, ionic strength and microhole diameter on ionic diode performance were investigated using cyclic voltammetry and chronoamperometry in a 4-electrode measurement cell. The reported ionic rectifier is simple to fabricate, and it shows good rectification even in high ionic strength media.","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/elan.12033","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143446815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interaction of a Third-Generation Tyrosine Kinase Inhibitor with dsDNA: Electrochemical and Spectroscopic Studies

IF 2.7 3区化学

Electroanalysis Pub Date : 2025-02-19 DOI: 10.1002/elan.12030

Kamila Koszelska, Monika Wypych, Mateusz Kciuk, Dariusz Guziejewski, Radovan Metelka, Sylwia Smarzewska

{"title":"Interaction of a Third-Generation Tyrosine Kinase Inhibitor with dsDNA: Electrochemical and Spectroscopic Studies","authors":"Kamila Koszelska, Monika Wypych, Mateusz Kciuk, Dariusz Guziejewski, Radovan Metelka, Sylwia Smarzewska","doi":"10.1002/elan.12030","DOIUrl":"https://doi.org/10.1002/elan.12030","url":null,"abstract":"In the current study, an evaluation was conducted regarding potential interaction mechanisms occurring between ponatinib (Pntb), a tyrosine kinase inhibitor of third-generation and double-stranded deoxyribonucleic acid (dsDNA). The aim of these studies was to elucidate the mechanism underlying the interaction between Pntb and DNA. This understanding could not only shed light on the changes occurring within living organisms but also, in the future, facilitate the development of new drugs for cancer treatment and improve their therapeutic effectiveness. The interactions were examined using square wave voltammetry (SWV) and UV–Vis spectroscopy. In order to conduct voltammetric experiments, a glassy carbon electrode was used. The addition of dsDNA to ponatinib solution resulted in a decrease of current peaks of the latter and resulted in a positive peak potential shift, suggesting that the intercalative type of interaction is the most likely to occur. Studies with utilization of UV–Vis spectroscopy have revealed a hypochromic effect, resulting in lack of wavelength shift in absorption maximum, following the addition of DNA to ponatinib solution, and confirming that intercalation is the predominant interaction between Pntb and dsDNA. The calculated value of the binding constant for Pntb-dsDNA determined by SWV was equal to 1.71 × 107 M−1. The values calculated from UV–Vis spectroscopy, however, were 1.13 × 107 M−1.","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143446820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interaction of a Third-Generation Tyrosine Kinase Inhibitor with dsDNA: Electrochemical and Spectroscopic Studies

IF 2.7 3区化学

Electroanalysis Pub Date : 2025-02-19 DOI: 10.1002/elan.12030

Kamila Koszelska, Monika Wypych, Mateusz Kciuk, Dariusz Guziejewski, Radovan Metelka, Sylwia Smarzewska

{"title":"Interaction of a Third-Generation Tyrosine Kinase Inhibitor with dsDNA: Electrochemical and Spectroscopic Studies","authors":"Kamila Koszelska, Monika Wypych, Mateusz Kciuk, Dariusz Guziejewski, Radovan Metelka, Sylwia Smarzewska","doi":"10.1002/elan.12030","DOIUrl":"https://doi.org/10.1002/elan.12030","url":null,"abstract":"In the current study, an evaluation was conducted regarding potential interaction mechanisms occurring between ponatinib (Pntb), a tyrosine kinase inhibitor of third-generation and double-stranded deoxyribonucleic acid (dsDNA). The aim of these studies was to elucidate the mechanism underlying the interaction between Pntb and DNA. This understanding could not only shed light on the changes occurring within living organisms but also, in the future, facilitate the development of new drugs for cancer treatment and improve their therapeutic effectiveness. The interactions were examined using square wave voltammetry (SWV) and UV–Vis spectroscopy. In order to conduct voltammetric experiments, a glassy carbon electrode was used. The addition of dsDNA to ponatinib solution resulted in a decrease of current peaks of the latter and resulted in a positive peak potential shift, suggesting that the intercalative type of interaction is the most likely to occur. Studies with utilization of UV–Vis spectroscopy have revealed a hypochromic effect, resulting in lack of wavelength shift in absorption maximum, following the addition of DNA to ponatinib solution, and confirming that intercalation is the predominant interaction between Pntb and dsDNA. The calculated value of the binding constant for Pntb-dsDNA determined by SWV was equal to 1.71 × 107 M−1. The values calculated from UV–Vis spectroscopy, however, were 1.13 × 107 M−1.","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143446816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rectified Ion Transport with Low-Cost Ionic Diodes Based on Sulfonated Poly-(Phenylene-Oxide)

IF 2.7 3区化学

Electroanalysis Pub Date : 2025-02-19 DOI: 10.1002/elan.12033

Asandiswa Mfenguza, Luthando Tshwenya, Dimpo S. Sipuka, Oluchi V. Nkwachukwu, Keneiloe Khoabane Sikhwivhilu, Frank Marken, Omotayo A. Arotiba

{"title":"Rectified Ion Transport with Low-Cost Ionic Diodes Based on Sulfonated Poly-(Phenylene-Oxide)","authors":"Asandiswa Mfenguza, Luthando Tshwenya, Dimpo S. Sipuka, Oluchi V. Nkwachukwu, Keneiloe Khoabane Sikhwivhilu, Frank Marken, Omotayo A. Arotiba","doi":"10.1002/elan.12033","DOIUrl":"https://doi.org/10.1002/elan.12033","url":null,"abstract":"Ionic rectifiers/diodes are devices with potential applications in water treatment (desalination) and sensors. Diode preparation sometimes involves expensive processes such as laser drilling and thus the need for simpler and low-cost methods. We developed a low-cost cation rectifying hybrid membrane ionic rectifier where a microporous sulfonated poly-(2,6-dimethyl phenylene oxide) (SPPO) was asymmetrically attached to a microhole region in a polypropylene adhesive tape substrate. Contact angle measurements showed that SPPO is hydrophilic with a 62° angle. In comparison, the polypropylene adhesive tape and SPPO within it are hydrophobic with angles of 101° and 87°, respectively, contributing to the diode's stability in water. Zeta potential measurements confirmed the negative charge of the SPPO surface in all electrolyte solutions. Scanning electron microscopy revealed that the punctured tape substrate has a 3–4 µm microhole and a thickness of about 25 µm. The SPPO membrane is ≈29 µm thick with a smooth cross-sectional surface. The effects of electrolyte, ionic strength and microhole diameter on ionic diode performance were investigated using cyclic voltammetry and chronoamperometry in a 4-electrode measurement cell. The reported ionic rectifier is simple to fabricate, and it shows good rectification even in high ionic strength media.","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/elan.12033","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143446817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lead(II) Determination in Aqueous and Firearm Discharge Residue Samples Using A Bistriazole-Modified Electrochemical Sensor

IF 2.7 3区化学

Electroanalysis Pub Date : 2025-02-18 DOI: 10.1002/elan.12026

Brenda R. L. Freire, Maria E. da C. V. Nascimento, Jonatas de Oliveira S. Silva, Carla L. C. Meira, Mauricio M. Victor, Eliana M. Sussuchi

{"title":"Lead(II) Determination in Aqueous and Firearm Discharge Residue Samples Using A Bistriazole-Modified Electrochemical Sensor","authors":"Brenda R. L. Freire, Maria E. da C. V. Nascimento, Jonatas de Oliveira S. Silva, Carla L. C. Meira, Mauricio M. Victor, Eliana M. Sussuchi","doi":"10.1002/elan.12026","DOIUrl":"https://doi.org/10.1002/elan.12026","url":null,"abstract":"The detection of heavy metals is necessary due to their toxic characteristics and bioaccumulation potential, which can be harmful to living organisms. Chemically modified electrodes have been widely used as an alternative in the detection of heavy metal ions, aiming for improved selectivity resulting from specific interactions with these analytes. Therefore, ligands derived from bistriazolic compounds emerge as new materials capable of interacting with metallic ions, potentially enhancing the detectability of the electrode. In this context, this work aims to obtain an electrochemical sensor based on a modifier derived from bistriazoles for the determination of lead(II) ions in different samples. The 1,3-bis(4-ethyl-1H−1,2,3-triazol-1-yl)propan-2-one (BT) was characterized using spectroscopic, spectrometric, and electrochemical techniques. Additionally, a method for the determination of lead(II) ions was developed using differential pulse voltammetry (DPV), where the bis-triazole modified electrode demonstrated remarkable detectability for Pb2+. Optimizations of the scan medium and DPV technique parameters showed a significant increase in the analytical signal current for Pb2+. An analytical curve was obtained, and the developed method achieved a limit of detection of 0.10 nmol L−1. The method was applied to quantify the analyte in tap water, river water, and firearm discharge residue samples with recovery values ranging from 87.8% to 118%, highlighting the reliability and precision of the developed method.","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143438889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Scrutinizing the Basis of Pd Electrochemistry: An Accurate Assessment of the Electrochemically Active Surface Area 探究钯电化学的基础：准确评估电化学活性表面积

IF 2.7 3区化学

Electroanalysis Pub Date : 2025-02-18 DOI: 10.1002/elan.12027

Nihat Ege Şahin, Wilian Jesus Pech-Rodríguez

{"title":"Scrutinizing the Basis of Pd Electrochemistry: An Accurate Assessment of the Electrochemically Active Surface Area","authors":"Nihat Ege Şahin, Wilian Jesus Pech-Rodríguez","doi":"10.1002/elan.12027","DOIUrl":"https://doi.org/10.1002/elan.12027","url":null,"abstract":"Palladium nanoparticles supported on a pretreated carbon substrate (Pd/C) were synthesized from a surfactant-free microwave-heated ethylene glycol without any external reducing agent and characterized by high-resolution electron transmission microscopy, thermogravimetric analysis, and X-ray diffraction analysis. Cyclic voltammetry was effectively employed to scrutinize the electrochemical processes such as Pd hydrogen interactions including hydrogen adsorption, absorption, desorption, and hydrogen evolution as well as Pd–oxygen interactions like the oxide formation and the subsequent reduction of the oxide layer. The electrochemical oxidation of palladium was clearly indicated at the potential ranging from 0.78 to 1.20 V versus reversible hydrogen electrode (RHE) in the anodic scan direction whereas the corresponding reduction peak was observed with a broad peak centered at 0.79 V versus RHE in the reverse scan. Therefore, an accurate evaluation of the EASA measurements on ultrathin film palladium (Pd/C) electrodes in acidic (0.5 mol L−1 H2SO4, pH ∼ 1) media was successfully conducted. Moreover, the steady-state cyclic voltammetry (CV) measurements have been conducted at the lowest scan rate of 1 mV s−1, enabling obtaining of hydrogen adsorption, absorption, and desorption reaction features without concurrent. Besides, Pd/C electrocatalyst exhibited 129 mV overpotential yielding a cathodic current density of 10 mA cm−2 toward hydrogen evolution reaction. This study outlines the description of practical experimental conditions essential for accurately determining the EASA that facilitates a comprehensive evaluation of their electrochemical performance.","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/elan.12027","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143438886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lead(II) Determination in Aqueous and Firearm Discharge Residue Samples Using A Bistriazole-Modified Electrochemical Sensor

IF 2.7 3区化学

Electroanalysis Pub Date : 2025-02-18 DOI: 10.1002/elan.12026

Brenda R. L. Freire, Maria E. da C. V. Nascimento, Jonatas de Oliveira S. Silva, Carla L. C. Meira, Mauricio M. Victor, Eliana M. Sussuchi

{"title":"Lead(II) Determination in Aqueous and Firearm Discharge Residue Samples Using A Bistriazole-Modified Electrochemical Sensor","authors":"Brenda R. L. Freire, Maria E. da C. V. Nascimento, Jonatas de Oliveira S. Silva, Carla L. C. Meira, Mauricio M. Victor, Eliana M. Sussuchi","doi":"10.1002/elan.12026","DOIUrl":"https://doi.org/10.1002/elan.12026","url":null,"abstract":"The detection of heavy metals is necessary due to their toxic characteristics and bioaccumulation potential, which can be harmful to living organisms. Chemically modified electrodes have been widely used as an alternative in the detection of heavy metal ions, aiming for improved selectivity resulting from specific interactions with these analytes. Therefore, ligands derived from bistriazolic compounds emerge as new materials capable of interacting with metallic ions, potentially enhancing the detectability of the electrode. In this context, this work aims to obtain an electrochemical sensor based on a modifier derived from bistriazoles for the determination of lead(II) ions in different samples. The 1,3-bis(4-ethyl-1H−1,2,3-triazol-1-yl)propan-2-one (BT) was characterized using spectroscopic, spectrometric, and electrochemical techniques. Additionally, a method for the determination of lead(II) ions was developed using differential pulse voltammetry (DPV), where the bis-triazole modified electrode demonstrated remarkable detectability for Pb2+. Optimizations of the scan medium and DPV technique parameters showed a significant increase in the analytical signal current for Pb2+. An analytical curve was obtained, and the developed method achieved a limit of detection of 0.10 nmol L−1. The method was applied to quantify the analyte in tap water, river water, and firearm discharge residue samples with recovery values ranging from 87.8% to 118%, highlighting the reliability and precision of the developed method.","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143438887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0