Electroanalysis最新文献

{"title":"Flexible Electrochemical Sensing: Compact and Efficient Detection of Bisphenol A Using Copper Nanoparticle Decorated Laser-Induced Graphene-Based Electrode","authors":"Xiao Han,&nbsp;Yijing Ai,&nbsp;Lisi Wang,&nbsp;Tao Liu,&nbsp;Amir Badshah,&nbsp;Xiaojuan Hu,&nbsp;Zhitan Huang,&nbsp;Ahmad Mansoor,&nbsp;Wei Sun","doi":"10.1002/elan.12025","DOIUrl":"https://doi.org/10.1002/elan.12025","url":null,"abstract":"<p>Bisphenol A (BPA) exposure poses significant health risks, making its analysis essential. This study presents a portable electrochemical sensing platform using copper nanoparticles (CuNPs) decorated on a laser-induced graphene (LIG) electrode (CuNPs@LIGE). The platform is created through a one-step laser-induced synthesis that combines polyimide and metal precursors, resulting in a three-dimensional porous structure. The sensor utilizes linear scan voltammetry for BPA detection with a smartphone-connected electrochemical workstation. The presence of CuNPs in LIG enhances electrical conductivity and response signals. Under optimal conditions, the sensor achieves a detection range from 0.1 μmol/L to 10.0 mmol/L and a low detection limit of 0.033 μmol/L (3<i>σ</i>), demonstrating good stability and selectivity. Additionally, it shows recovery rates between 95.71% and 99.17% for BPA detection in seawater samples, making it a strong candidate for rapid BPA monitoring applications.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143423977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New Screen-Printed Carbon Electrodes Molecularly Modified with Methylphenidate Film for Electrochemical Determination of Dopamine by Linear Scan Voltammetry","authors":"Fernando Riesco,&nbsp;Gloria A. Cosco-Salguero,&nbsp;Edgar Nagles,&nbsp;Johisner Penagos-Llanos,&nbsp;Rodrigo Segura,&nbsp;John Hurtado","doi":"10.1002/elan.12028","DOIUrl":"https://doi.org/10.1002/elan.12028","url":null,"abstract":"<p>The development of new sensors for dopamine (DP) detection is crucial due to its role as one of the most important neurotransmitters for maintaining mental health. In this context, a novel and simple 2D screen-printed carbon electrode (SPCE) molecularly modified electrode with a methylphenidate film was developed. This electrode exhibited notable activity in DP oxidation at potential values below 0.3 V, achieving a 300% increase in anodic current compared to the unmodified SPCE in an acidic environment (pH 3.0) with phosphate buffer solution. Cyclic voltammetry and electrochemical impedance spectroscopy were used to characterize the electrode's electrochemical behavior. The electrode achieved a DP detection limit of 0.15 <i>µ</i>mol/L using linear scan voltammetry. Interference studies with ascorbic acid and uric acid confirmed the electrode's selectivity for DP detection. The sensor's effectiveness was validated using real human urine samples, demonstrating accurate and reliable performance.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143423976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flexible Electrochemical Sensing: Compact and Efficient Detection of Bisphenol A Using Copper Nanoparticle Decorated Laser-Induced Graphene-Based Electrode","authors":"Xiao Han,&nbsp;Yijing Ai,&nbsp;Lisi Wang,&nbsp;Tao Liu,&nbsp;Amir Badshah,&nbsp;Xiaojuan Hu,&nbsp;Zhitan Huang,&nbsp;Ahmad Mansoor,&nbsp;Wei Sun","doi":"10.1002/elan.12025","DOIUrl":"https://doi.org/10.1002/elan.12025","url":null,"abstract":"<p>Bisphenol A (BPA) exposure poses significant health risks, making its analysis essential. This study presents a portable electrochemical sensing platform using copper nanoparticles (CuNPs) decorated on a laser-induced graphene (LIG) electrode (CuNPs@LIGE). The platform is created through a one-step laser-induced synthesis that combines polyimide and metal precursors, resulting in a three-dimensional porous structure. The sensor utilizes linear scan voltammetry for BPA detection with a smartphone-connected electrochemical workstation. The presence of CuNPs in LIG enhances electrical conductivity and response signals. Under optimal conditions, the sensor achieves a detection range from 0.1 μmol/L to 10.0 mmol/L and a low detection limit of 0.033 μmol/L (3<i>σ</i>), demonstrating good stability and selectivity. Additionally, it shows recovery rates between 95.71% and 99.17% for BPA detection in seawater samples, making it a strong candidate for rapid BPA monitoring applications.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143423513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bimodal (Photo)electrochemical Sensor for Cetirizine Detection","authors":"Daniele Fumagalli,&nbsp;Wafa Aidli,&nbsp;Luigi Falciola,&nbsp;Valentina Pifferi","doi":"10.1002/elan.12018","DOIUrl":"https://doi.org/10.1002/elan.12018","url":null,"abstract":"<p>A bimodal sensor able to effectively detect cetirizine, an antihistaminic drug, was proposed. The device is based on the catalytic properties of silver and the photoactivity of TiO₂ and can be used as dual electrochemical-photoelectrochemical sensor, with good performances in cetirizine quantification both through the molecule's reduction and its photo-oxidation, with limits of detections of (3.2 ± 0.1) and (1.03 ± 0.08) µM, respectively. The use of these two materials allows for greater stability, robustness, and reusability compared to using two separate electrodes. Furthermore, a comparison of the results obtained with the two techniques can help in identifying and eliminating the effects of interferents, thus increasing the reliability of the detection.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/elan.12018","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143396880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bimodal (Photo)electrochemical Sensor for Cetirizine Detection","authors":"Daniele Fumagalli,&nbsp;Wafa Aidli,&nbsp;Luigi Falciola,&nbsp;Valentina Pifferi","doi":"10.1002/elan.12018","DOIUrl":"https://doi.org/10.1002/elan.12018","url":null,"abstract":"<p>A bimodal sensor able to effectively detect cetirizine, an antihistaminic drug, was proposed. The device is based on the catalytic properties of silver and the photoactivity of TiO₂ and can be used as dual electrochemical-photoelectrochemical sensor, with good performances in cetirizine quantification both through the molecule's reduction and its photo-oxidation, with limits of detections of (3.2 ± 0.1) and (1.03 ± 0.08) µM, respectively. The use of these two materials allows for greater stability, robustness, and reusability compared to using two separate electrodes. Furthermore, a comparison of the results obtained with the two techniques can help in identifying and eliminating the effects of interferents, thus increasing the reliability of the detection.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/elan.12018","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143397142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrochemical Monitoring of the Impact of Antibiotic Agents on Pseudomonas aeruginosa Phenazine Metabolite Production Rates","authors":"Olivia M. Clay,&nbsp;Courtney J. Weber,&nbsp;Richard S. Anum,&nbsp;Olja Simoska","doi":"10.1002/elan.12021","DOIUrl":"https://doi.org/10.1002/elan.12021","url":null,"abstract":"&lt;p&gt;&lt;i&gt;Pseudomonas aeruginosa&lt;/i&gt; is an opportunistic pathogen responsible for a high percentage of nosocomial infections, particularly posing a threat to immunocompromised patients. The increased use of antibacterial agents has led to the emergence of antibiotic resistance mechanisms in this pathogen, exacerbating challenges in treating &lt;i&gt;P. aeruginosa&lt;/i&gt; infections. Previous studies have correlated the endogenous production of phenazines in &lt;i&gt;P. aeruginosa&lt;/i&gt; to the development of antibiotic resistance in the bacterium. Phenazines are nitrogen-containing heterocyclic compounds endogenously produced by &lt;i&gt;P. aeruginosa&lt;/i&gt; as redox-active biogenic signaling molecules during early infection stages. While several studies have provided qualitative insights into the effects of different antibiotics on &lt;i&gt;P. aeruginosa&lt;/i&gt; growth, quantitative reports on the changes in &lt;i&gt;P. aeruginosa&lt;/i&gt; cellular communication and metabolite production dynamics following antibiotic exposure are limited. Addressing this knowledge gap, this study reports real-time electrochemical quantification of phenazine virulence metabolites in both wild-type PA14 and clinical PA2114 strains of &lt;i&gt;P. aeruginosa&lt;/i&gt; with varying levels of antibiotic resistance. Specifically, the impact of antibacterial agent ciprofloxacin (CIP) at different concentrations (0, 0.05, and 1 mg L&lt;sup&gt;−1&lt;/sup&gt; CIP) on phenazine production in these &lt;i&gt;P. aeruginosa&lt;/i&gt; strains was electrochemically monitored directly from bacterial cultures over a 48-h period. Square-wave voltammetry was utilized for quantitative monitoring of two phenazines, namely pyocyanin (PYO) and 5-methylphenazine-1-carboxylic acid (5-MCA), correlating electrical current signal at a unique redox potential to the phenazine concentration. The results indicate distinct phenazine redox responses of the clinical isolate PA2114 strain and wild-type PA14 strain due to antibiotic stress. Under optimal cell growth conditions without CIP exposure, the PA2114 strain with higher antibiotic resistance produced increasing PYO concentrations over 48 h, peaking at 84 ± 9 μM PYO. In contrast, the PYO levels produced by the wild-type strain plateaued and decreased after 24 h of growth, reaching a maximum PYO concentration of 65 ± 3 μM. Exposure to 0.05 mg L&lt;sup&gt;−1&lt;/sup&gt; CIP led to marginally higher PYO concentrations in the clinical strain (88 ± 9 μM) while the wild-type strain displayed a notable decrease in PYO concentration (54 ± 4 μM). Additionally, cellular growth with 1 mg L&lt;sup&gt;−1&lt;/sup&gt; CIP resulted in a decreased maximum PYO concentration for the clinical strain (70 ± 3 μM) and a substantially decreased PYO concentration for the wild-type strain (11 ± 5 μM). These differences in PYO production are attributed to distinctive changes in phenazine biosynthesis dynamics in different &lt;i&gt;P. aeruginosa&lt;/i&gt; strains and the addition of CIP. Furthermore, this study shows the monitoring of phenazine biosynthesis dynamics through the detection of the","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143362518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Voltammetric Simultaneous Quantification of Lapachone Isomers In Plant Extracts Using Graphite–Epoxy Composite Electrode","authors":"Joseany M. S. Almeida,&nbsp;Andrea R. da Silva,&nbsp;Ana Beatriz O. Azevedo,&nbsp;Marlin J. Pedrozo-Peñafiel,&nbsp;Carlos A. T. Toloza,&nbsp;Ricardo Q. Aucélio","doi":"10.1002/elan.12023","DOIUrl":"https://doi.org/10.1002/elan.12023","url":null,"abstract":"<p>The method developed for the determination of lapachone isomers (<i>α</i>- and <i>β</i>-lapachones) involves the use of square wave voltammetry (SWV) with an electrode based on epoxy–graphite composite. The electrolytic aqueous solution contained a cationic surfactant (CTAB), phosphate buffer (pH 6.0), and KNO₃. The addition of CTAB enhanced analyte diffusion into the electrode–solution interface, improving detection through SWV. Under chosen conditions, <i>β</i>-lapachone and <i>α</i>-lapachone respectively present reversible and quasireversible processes. The analytical signals were detected at the specific potentials of −370 mV (<i>α</i>-lapachone) and −190 mV (<i>β</i>-lapachone) using 140 s preconcentration at +400 mV. The SWV parameters used include 30 Hz frequency, 40 mV pulse amplitude, and 20 mV potential step. Instrumental detection limits were 2.4 × 10⁻⁷ mol L⁻¹ and 1.4 × 10⁻⁷ mol L⁻¹ respectively for <i>α</i>-lapachone and <i>β</i>-lapachone. Lapachol and, in a lesser extent, sulfonated <i>β</i>-lapachone interfere with both analyte signals, requiring liquid–liquid extraction prior to the determination of <i>α</i>-lapachone and <i>β</i>-lapachone in ethanolic plant (heartwood of the <i>Tabebuia impetiginosa</i>) extract. The results obtained using SWV agreed with those achieved by high-performance liquid chromatography.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143362339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methyl Viologen as a Redox Mediator for Scanning Electrochemical Microscopy to Study Copper Corrosion Under Deaerated Conditions","authors":"Emmanuel Mena-Morcillo,&nbsp;Reza Moshrefi,&nbsp;Mehran Behazin,&nbsp;Peter George Keech,&nbsp;Samantha Michelle Gateman","doi":"10.1002/elan.12016","DOIUrl":"https://doi.org/10.1002/elan.12016","url":null,"abstract":"<p>Scanning electrochemical microscopy (SECM) is a popular tool to study corrosion with high spatial resolution. The feedback mode of SECM involves the use of an added redox mediator in solution to probe local surface kinetics. Depending on the redox mediator's oxidation state and formal potential, as well as the corroding metal's corrosion potential, the electroactive species can potentially polarize the substrate and alter the corrosion behavior at the macro and/or microscale. Therefore, the choice of redox mediator is material dependent. This study explored the use of methyl viologen (MV) as a potentially ideal redox mediator for studying the local reactivity of copper. The SECM solutions were deaerated prior to SECM approach curve measurements to avoid a convoluted response from the oxygen reduction reaction at the ultramicroelectrode. Since the formal potential of MV is lower than the corrosion potential of Cu and undergoes oxidation to regenerate at the substrate's surface, the redox mediator was successfully implemented for kinetic measurements without inducing oxidative etching, ultramicroelectrode fouling, or macroscale corrosion. This work highlights the importance of redox mediator choice for SECM corrosion studies to avoid misinterpretation of data and provides a systematic method of making such decision for accurate measurements.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/elan.12016","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143362519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Voltammetric Simultaneous Quantification of Lapachone Isomers In Plant Extracts Using Graphite–Epoxy Composite Electrode","authors":"Joseany M. S. Almeida,&nbsp;Andrea R. da Silva,&nbsp;Ana Beatriz O. Azevedo,&nbsp;Marlin J. Pedrozo-Peñafiel,&nbsp;Carlos A. T. Toloza,&nbsp;Ricardo Q. Aucélio","doi":"10.1002/elan.12023","DOIUrl":"https://doi.org/10.1002/elan.12023","url":null,"abstract":"<p>The method developed for the determination of lapachone isomers (<i>α</i>- and <i>β</i>-lapachones) involves the use of square wave voltammetry (SWV) with an electrode based on epoxy–graphite composite. The electrolytic aqueous solution contained a cationic surfactant (CTAB), phosphate buffer (pH 6.0), and KNO₃. The addition of CTAB enhanced analyte diffusion into the electrode–solution interface, improving detection through SWV. Under chosen conditions, <i>β</i>-lapachone and <i>α</i>-lapachone respectively present reversible and quasireversible processes. The analytical signals were detected at the specific potentials of −370 mV (<i>α</i>-lapachone) and −190 mV (<i>β</i>-lapachone) using 140 s preconcentration at +400 mV. The SWV parameters used include 30 Hz frequency, 40 mV pulse amplitude, and 20 mV potential step. Instrumental detection limits were 2.4 × 10⁻⁷ mol L⁻¹ and 1.4 × 10⁻⁷ mol L⁻¹ respectively for <i>α</i>-lapachone and <i>β</i>-lapachone. Lapachol and, in a lesser extent, sulfonated <i>β</i>-lapachone interfere with both analyte signals, requiring liquid–liquid extraction prior to the determination of <i>α</i>-lapachone and <i>β</i>-lapachone in ethanolic plant (heartwood of the <i>Tabebuia impetiginosa</i>) extract. The results obtained using SWV agreed with those achieved by high-performance liquid chromatography.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143362709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methyl Viologen as a Redox Mediator for Scanning Electrochemical Microscopy to Study Copper Corrosion Under Deaerated Conditions","authors":"Emmanuel Mena-Morcillo,&nbsp;Reza Moshrefi,&nbsp;Mehran Behazin,&nbsp;Peter George Keech,&nbsp;Samantha Michelle Gateman","doi":"10.1002/elan.12016","DOIUrl":"https://doi.org/10.1002/elan.12016","url":null,"abstract":"<p>Scanning electrochemical microscopy (SECM) is a popular tool to study corrosion with high spatial resolution. The feedback mode of SECM involves the use of an added redox mediator in solution to probe local surface kinetics. Depending on the redox mediator's oxidation state and formal potential, as well as the corroding metal's corrosion potential, the electroactive species can potentially polarize the substrate and alter the corrosion behavior at the macro and/or microscale. Therefore, the choice of redox mediator is material dependent. This study explored the use of methyl viologen (MV) as a potentially ideal redox mediator for studying the local reactivity of copper. The SECM solutions were deaerated prior to SECM approach curve measurements to avoid a convoluted response from the oxygen reduction reaction at the ultramicroelectrode. Since the formal potential of MV is lower than the corrosion potential of Cu and undergoes oxidation to regenerate at the substrate's surface, the redox mediator was successfully implemented for kinetic measurements without inducing oxidative etching, ultramicroelectrode fouling, or macroscale corrosion. This work highlights the importance of redox mediator choice for SECM corrosion studies to avoid misinterpretation of data and provides a systematic method of making such decision for accurate measurements.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/elan.12016","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143362840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}