Electroanalysis最新文献

{"title":"Impedimetric Detection of Amyloid Beta (1–42) on Curcumin-Copper Complex Electropolymerized Graphite Electrode","authors":"Pelin Sayar,&nbsp;Meltem Maral,&nbsp;Esma Yildiz,&nbsp;Arzum Erdem","doi":"10.1002/elan.12049","DOIUrl":"https://doi.org/10.1002/elan.12049","url":null,"abstract":"<p>In the study, curcumin (Cur) electropolymerization on the surface of disposable pencil graphite electrode (PGE) was carried out using cyclic voltammetry (CV) technique. The interaction of curcumin electropolymerized on PGE surface with aluminum (Al), nickel (Ni), and copper (Cu) metals was investigated using differential pulse voltammetry (DPV) technique. It was observed that the highest interaction between curcumin–metal complexes occurred in the presence of Cu (II). Electrochemical characterization of poly (Cur)-Cu (II)/PGE was carried out by electrochemical impedance spectroscopy (EIS) and CV measurements. The detection of interaction of curcumin with Cu (II) in different concentration ratios was investigated by EIS technique. A<i>β</i> (1–42) peptide is known to play a significant role in the pathogenesis of Alzheimer's disease (AD). The immobilization of A<i>β</i> (1–42) on the PGE surface at different temperatures and its various concentration was optimized and accordingly, the impedimetric results were recorded. The limit of detection for the analysis of A<i>β</i> (1–42) on the PGE surface was calculated over a linear concentration range of 1–20 µM and found to be 0.99 µM. The immobilization of A<i>β</i> (1–42) peptide onto the electrode surface was performed by using poly (Cur)/PGE, Cu (II)/PGE, and poly (Cur)-Cu (II)/PGE as well as PGE. According to these results, the highest interaction was obtained in the presence of A<i>β</i> (1–42) peptide onto the surface of poly (Cur)-Cu (II)/PGE. The biointeraction of A<i>β</i> (1–42) peptide with curcumin-Cu (II) complex offers promising opportunities for the development of different approaches and potential drugs for the diagnosis of AD. The determination of the biointeraction of A<i>β</i> (1–42) peptide with curcumin-Cu(II) complex based on the impedimetric method holds promise for the development of different approaches to the diagnosis and new molecules for the treatment of AD.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 5","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/elan.12049","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143909114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impedimetric Detection of Amyloid Beta (1–42) on Curcumin-Copper Complex Electropolymerized Graphite Electrode","authors":"Pelin Sayar,&nbsp;Meltem Maral,&nbsp;Esma Yildiz,&nbsp;Arzum Erdem","doi":"10.1002/elan.12049","DOIUrl":"https://doi.org/10.1002/elan.12049","url":null,"abstract":"<p>In the study, curcumin (Cur) electropolymerization on the surface of disposable pencil graphite electrode (PGE) was carried out using cyclic voltammetry (CV) technique. The interaction of curcumin electropolymerized on PGE surface with aluminum (Al), nickel (Ni), and copper (Cu) metals was investigated using differential pulse voltammetry (DPV) technique. It was observed that the highest interaction between curcumin–metal complexes occurred in the presence of Cu (II). Electrochemical characterization of poly (Cur)-Cu (II)/PGE was carried out by electrochemical impedance spectroscopy (EIS) and CV measurements. The detection of interaction of curcumin with Cu (II) in different concentration ratios was investigated by EIS technique. A<i>β</i> (1–42) peptide is known to play a significant role in the pathogenesis of Alzheimer's disease (AD). The immobilization of A<i>β</i> (1–42) on the PGE surface at different temperatures and its various concentration was optimized and accordingly, the impedimetric results were recorded. The limit of detection for the analysis of A<i>β</i> (1–42) on the PGE surface was calculated over a linear concentration range of 1–20 µM and found to be 0.99 µM. The immobilization of A<i>β</i> (1–42) peptide onto the electrode surface was performed by using poly (Cur)/PGE, Cu (II)/PGE, and poly (Cur)-Cu (II)/PGE as well as PGE. According to these results, the highest interaction was obtained in the presence of A<i>β</i> (1–42) peptide onto the surface of poly (Cur)-Cu (II)/PGE. The biointeraction of A<i>β</i> (1–42) peptide with curcumin-Cu (II) complex offers promising opportunities for the development of different approaches and potential drugs for the diagnosis of AD. The determination of the biointeraction of A<i>β</i> (1–42) peptide with curcumin-Cu(II) complex based on the impedimetric method holds promise for the development of different approaches to the diagnosis and new molecules for the treatment of AD.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 5","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/elan.12049","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143909115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cover Picture: (Electroanalysis 5/2025)","authors":"","doi":"10.1002/elan.202580105","DOIUrl":"https://doi.org/10.1002/elan.202580105","url":null,"abstract":"<p>Cover picture provided by Dr. Elena Benito-Peña and Dr. Susana Campuzano. <i>Electroanalysis</i> covers all branches of electroanalytical chemistry, including both fundamental and application papers as well as reviews dealing with analytical voltammetry, potentiometry, new electrochemical sensors and detection schemes, nanoscale electrochemistry, advanced electromaterials, nanobioelectronics, point-of-care diagnostics, wearable sensors, and practical applications.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 5","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/elan.202580105","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143877789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cover Picture: (Electroanalysis 5/2025)","authors":"","doi":"10.1002/elan.202580105","DOIUrl":"https://doi.org/10.1002/elan.202580105","url":null,"abstract":"<p>Cover picture provided by Dr. Elena Benito-Peña and Dr. Susana Campuzano. <i>Electroanalysis</i> covers all branches of electroanalytical chemistry, including both fundamental and application papers as well as reviews dealing with analytical voltammetry, potentiometry, new electrochemical sensors and detection schemes, nanoscale electrochemistry, advanced electromaterials, nanobioelectronics, point-of-care diagnostics, wearable sensors, and practical applications.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 5","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/elan.202580105","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143877788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrochemical Immunosensing of The Neo-Antigen Collagen Type I α 1 to Assist in the Personalized Management of Advanced Colorectal Cancer","authors":"Eloy Povedano,&nbsp;Antonella Miglione,&nbsp;Ana Montero-Calle,&nbsp;Stefano Cinti,&nbsp;José M. Pingarrón,&nbsp;Rodrigo Barderas,&nbsp;Susana Campuzano","doi":"10.1002/elan.12052","DOIUrl":"https://doi.org/10.1002/elan.12052","url":null,"abstract":"<p>Biomarkers known as neo-antigens, such as collagen, are increasingly considered of interest for the diagnosis and therapeutic monitoring of oncology patients. This work reports the development of an attractive strategy for the amperometric immunodetection of Collagen type I <i>α</i> 1 (COL1A1), involving magnetic microbeads for the construction of the immunoplatform, a sandwich assay format using specific capture and biotinylated-detector antibodies, horseradish peroxidase labeling, and amperometric transduction at disposable screen-printed carbon electrodes. The developed methodology allowed the selective, rapid, simple, and reliable detection of COL1A1 in the 0.051–10 ng mL⁻¹ linear range with a detection limit of 15 pg mL⁻¹. The developed immunoplatform was successfully applied to the analysis of COL1A1 in plasma and tissue extracts from healthy individuals and colorectal cancer patients. The results obtained proved the potential of this neo-antigen as biomarker for diagnosis of this disease.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 4","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143871506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrochemical Immunosensing of The Neo-Antigen Collagen Type I α 1 to Assist in the Personalized Management of Advanced Colorectal Cancer","authors":"Eloy Povedano,&nbsp;Antonella Miglione,&nbsp;Ana Montero-Calle,&nbsp;Stefano Cinti,&nbsp;José M. Pingarrón,&nbsp;Rodrigo Barderas,&nbsp;Susana Campuzano","doi":"10.1002/elan.12052","DOIUrl":"https://doi.org/10.1002/elan.12052","url":null,"abstract":"<p>Biomarkers known as neo-antigens, such as collagen, are increasingly considered of interest for the diagnosis and therapeutic monitoring of oncology patients. This work reports the development of an attractive strategy for the amperometric immunodetection of Collagen type I <i>α</i> 1 (COL1A1), involving magnetic microbeads for the construction of the immunoplatform, a sandwich assay format using specific capture and biotinylated-detector antibodies, horseradish peroxidase labeling, and amperometric transduction at disposable screen-printed carbon electrodes. The developed methodology allowed the selective, rapid, simple, and reliable detection of COL1A1 in the 0.051–10 ng mL⁻¹ linear range with a detection limit of 15 pg mL⁻¹. The developed immunoplatform was successfully applied to the analysis of COL1A1 in plasma and tissue extracts from healthy individuals and colorectal cancer patients. The results obtained proved the potential of this neo-antigen as biomarker for diagnosis of this disease.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 4","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143871505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One-Pot Solvothermal Synthesis of PtAu/3d Graphene Aerogels for Methanol Fuel Cells","authors":"Xiao Yu,&nbsp;Xiaoyu Zhou,&nbsp;Yuyan Sun,&nbsp;Fenghua Li,&nbsp;Liqiang Luo,&nbsp;Qixian Zhang","doi":"10.1002/elan.12051","DOIUrl":"https://doi.org/10.1002/elan.12051","url":null,"abstract":"<p>Graphene aerogel (GA), known for their loose and porous three-dimensional structures, has been extensively studied and applied in various fields due to their exceptional mechanical strength, thermal conductivity, and electrical properties. However, GA is usually made by freeze-drying method, which is expensive and time-consuming. In this study, a one-pot hydrothermal synthesis method was proposed to successfully fabricate platinum–gold nanoparticle-embedded graphene aerogels (PtAu/3DGA). The resulting PtAu/3DGA material exhibits a highly cross-linked 3D porous structure, a large surface area, and uniformly dispersed metal nanoparticles, which mainly contributes to its outstanding properties. As a methanol fuel cell catalyst, PtAu/3DGA achieves a catalytic activity of 638.3 mA mg⁻¹ and maintains excellent long-term stability. This approach not only improves the high cost and limited catalytic performance of platinum-based alternatives but also offers a scalable and efficient fabrication pathway. The outstanding performance of PtAu/3DGA highlights its potential applications in various fields, including fuel cells, supercapacitors, photocatalysis, and sensors. This work provides a promising strategy for the development of advanced materials with multifunctional applications.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 4","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143852695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One-Pot Solvothermal Synthesis of PtAu/3d Graphene Aerogels for Methanol Fuel Cells","authors":"Xiao Yu,&nbsp;Xiaoyu Zhou,&nbsp;Yuyan Sun,&nbsp;Fenghua Li,&nbsp;Liqiang Luo,&nbsp;Qixian Zhang","doi":"10.1002/elan.12051","DOIUrl":"https://doi.org/10.1002/elan.12051","url":null,"abstract":"<p>Graphene aerogel (GA), known for their loose and porous three-dimensional structures, has been extensively studied and applied in various fields due to their exceptional mechanical strength, thermal conductivity, and electrical properties. However, GA is usually made by freeze-drying method, which is expensive and time-consuming. In this study, a one-pot hydrothermal synthesis method was proposed to successfully fabricate platinum–gold nanoparticle-embedded graphene aerogels (PtAu/3DGA). The resulting PtAu/3DGA material exhibits a highly cross-linked 3D porous structure, a large surface area, and uniformly dispersed metal nanoparticles, which mainly contributes to its outstanding properties. As a methanol fuel cell catalyst, PtAu/3DGA achieves a catalytic activity of 638.3 mA mg⁻¹ and maintains excellent long-term stability. This approach not only improves the high cost and limited catalytic performance of platinum-based alternatives but also offers a scalable and efficient fabrication pathway. The outstanding performance of PtAu/3DGA highlights its potential applications in various fields, including fuel cells, supercapacitors, photocatalysis, and sensors. This work provides a promising strategy for the development of advanced materials with multifunctional applications.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 4","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143852696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrochemical Modulation of MoS2 Structures to Boost Hydrogen Evolution Reaction Efficiency","authors":"Venumbaka Maneesh Reddy,&nbsp;Bhanu Chandra Marepally,&nbsp;Ranjithkumar Selvam,&nbsp;Saravanan Gengan,&nbsp;Maiyalagan Thandavarayan,&nbsp;Selvakumar Duraisamy","doi":"10.1002/elan.12046","DOIUrl":"https://doi.org/10.1002/elan.12046","url":null,"abstract":"<p>The use of molybdenum disulfide (MoS₂) as a non-noble metal electrocatalyst for the hydrogen evolution reaction (HER) has gained significant attention due to its affordability and the ease of modifying factors such as voltage, current, duration, and the composition and concentration of the electrolyte solution using electrodeposition techniques. To increase the number of active sites on the surface of MoS₂, fine nanoscale tailoring of the crystalline phase is necessary. This can be accomplished using electrochemical phase formation. In this study, four types of MoS₂ nanoparticles are successfully electrodeposited on copper foil substrates using a mixture of Na₂MoO₄ and Na₂S electrolytes, namely fine nodular MoS₂ (FNMoS₂), small sheet MoS₂ (SSMoS₂), highly porous MoS₂ (HPMoS₂), and low porous MoS₂ (LPMoS₂), with nanoparticles of FNMoS₂, SSMoS₂, HPMoS₂, and LPMoS₂ being produced at potentials of −0.9, −1.0, −1.1, and −1.2, respectively. The electrochemical performance of these nanoparticles on HER is carefully investigated using techniques such as high-resolution transmission electron microscopy (HRTEM), X-ray diffraction (XRD), and energy dispersive spectroscopy. Linear sweep voltammetry, Tafel plot analysis, and electrochemical impedance spectroscopy are used to study the electrocatalytic performance of HER in a 0.5 M KOH electrolyte. HPMoS₂ electrodeposited at −1.1 V for 200 s had a HER current density of 10 mA cm⁻² at <i>η</i> = −270 mV and a Tafel slope (vs RHE) of 35.8 mV/dec, lower than that of FNMoS₂, SSMoS₂, and LPMoS₂. These results have significant implications for the development of low cost, affordable, and environmentally friendly electrochemical methods of producing hydrogen, and pave the way for further research in this field.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 4","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143835998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrochemical Modulation of MoS2 Structures to Boost Hydrogen Evolution Reaction Efficiency","authors":"Venumbaka Maneesh Reddy,&nbsp;Bhanu Chandra Marepally,&nbsp;Ranjithkumar Selvam,&nbsp;Saravanan Gengan,&nbsp;Maiyalagan Thandavarayan,&nbsp;Selvakumar Duraisamy","doi":"10.1002/elan.12046","DOIUrl":"https://doi.org/10.1002/elan.12046","url":null,"abstract":"<p>The use of molybdenum disulfide (MoS₂) as a non-noble metal electrocatalyst for the hydrogen evolution reaction (HER) has gained significant attention due to its affordability and the ease of modifying factors such as voltage, current, duration, and the composition and concentration of the electrolyte solution using electrodeposition techniques. To increase the number of active sites on the surface of MoS₂, fine nanoscale tailoring of the crystalline phase is necessary. This can be accomplished using electrochemical phase formation. In this study, four types of MoS₂ nanoparticles are successfully electrodeposited on copper foil substrates using a mixture of Na₂MoO₄ and Na₂S electrolytes, namely fine nodular MoS₂ (FNMoS₂), small sheet MoS₂ (SSMoS₂), highly porous MoS₂ (HPMoS₂), and low porous MoS₂ (LPMoS₂), with nanoparticles of FNMoS₂, SSMoS₂, HPMoS₂, and LPMoS₂ being produced at potentials of −0.9, −1.0, −1.1, and −1.2, respectively. The electrochemical performance of these nanoparticles on HER is carefully investigated using techniques such as high-resolution transmission electron microscopy (HRTEM), X-ray diffraction (XRD), and energy dispersive spectroscopy. Linear sweep voltammetry, Tafel plot analysis, and electrochemical impedance spectroscopy are used to study the electrocatalytic performance of HER in a 0.5 M KOH electrolyte. HPMoS₂ electrodeposited at −1.1 V for 200 s had a HER current density of 10 mA cm⁻² at <i>η</i> = −270 mV and a Tafel slope (vs RHE) of 35.8 mV/dec, lower than that of FNMoS₂, SSMoS₂, and LPMoS₂. These results have significant implications for the development of low cost, affordable, and environmentally friendly electrochemical methods of producing hydrogen, and pave the way for further research in this field.</p>","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"37 4","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143835997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}