Journal of invertebrate pathology最新文献

{"title":"Molecular profiling of the Australian plague locust pathobiome reveals a microbial driver of population suppression","authors":"Simon R. Law ,&nbsp;Lachlan Dow ,&nbsp;Mohammad Hoque ,&nbsp;Ned Walsh ,&nbsp;Moazzem Khan ,&nbsp;Luke G. Barrett","doi":"10.1016/j.jip.2025.108402","DOIUrl":"10.1016/j.jip.2025.108402","url":null,"abstract":"<div><div>Despite recent advances in surveillance, forecasting, and management, locust plagues remain a chronic threat to global agriculture. Part of the intractability of this issue lies in the complex interplay of ecological factors driving locust population dynamics, of which the locust microbiome remains an understudied–but crucial–component. During the wet Australian summers of 2020-2022, forecasting models predicted that Australian plague locust (<em>Chortoicetes terminifera</em>) populations would reach plague proportions, while field-surveillance revealed the contrary. To investigate a putative microbiological cause for this population suppression, a diagnostic framework integrating metabarcoding, microbial isolation, genomic characterisation, and pathogenicity assays was applied. This approach identified a bacterial pathogen belonging to the <em>Serratia marcescens</em> species complex and demonstrated its entomopathogenicity through controlled feeding assays. Genome mining of the isolated <em>S. marcescens</em> strain revealed virulence factors associated with insecticidal activity, including urease-mediated cytotoxicity and metal-scavenging biosynthetic gene clusters. Finally, field population screening indicated that <em>S. marcescens</em> presence was not uniform across surveyed APL populations, suggesting that infections may be transient or epidemic in nature, potentially influenced by environmental conditions such as temperature and humidity. These findings stress the importance of microbial interactions in shaping locust population dynamics and establish a basis for future research into ecological strategies for locust control.</div></div>","PeriodicalId":16296,"journal":{"name":"Journal of invertebrate pathology","volume":"213 ","pages":"Article 108402"},"PeriodicalIF":2.4,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144718022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Virome of Solenopsis invicta (Hymenoptera: Formicidae): Intercontinental differences in the native and introduced ranges","authors":"Steven M. Valles ,&nbsp;Marina S. Ascunce ,&nbsp;Quentin D. Read ,&nbsp;Roxie L. White ,&nbsp;Robert K. Vander Meer","doi":"10.1016/j.jip.2025.108401","DOIUrl":"10.1016/j.jip.2025.108401","url":null,"abstract":"<div><div>A comprehensive survey of 430 <em>Solenopsis invicta</em> nests from 82 different sites in Argentina and the USA was conducted for all currently known viruses infecting, or associated with, the invasive red imported fire ant, <em>S. invicta</em>. Comparisons in viral abundance, diversity, and possible social form preferences were made. Monogyny was the more prevalent <em>S. invicta</em> colony social form detected on both continents. Seventeen of the twenty (i.e., 85%) known viruses associated with <em>S. invicta</em> were observed in Argentina, compared with 11 (55%) viruses detected in <em>S. invicta</em> in the USA. Two viruses, Solenopsis <em>invicta</em> virus-16 (SINV-16) and SINV-17, were not detected on either continent. Seven viruses, SINV-5, SINV-8, SINV-10, SINV-11, SINV-12, SINV-13, and Solenopsis <em>invicta</em> densovirus, were unique to Argentinean <em>S. invicta</em> (i.e., only detected in Argentina) and one virus, SINV-14, was unique to USA <em>S. invicta</em>. The mean number of viruses per nest was significantly (5.4-fold) greater in <em>S. invicta</em> from Argentina compared with <em>S. invicta</em> from the USA. Greater viral diversity and abundance in the native range, Argentina, compared with the introduced range, USA, supports the “enemy release hypothesis” to explain the disparity in <em>S. invicta</em> population levels and pest intensity between the two continents.</div></div>","PeriodicalId":16296,"journal":{"name":"Journal of invertebrate pathology","volume":"213 ","pages":"Article 108401"},"PeriodicalIF":3.6,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144698842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beauveria bassiana ERL836-mediated suppression of oxidative phosphorylation and immune response in fat body of Japanese pine sawyer beetle","authors":"Yu Lim Park,&nbsp;Jeong Seon Yu,&nbsp;Jong-Cheol Kim,&nbsp;Jae Su Kim","doi":"10.1016/j.jip.2025.108403","DOIUrl":"10.1016/j.jip.2025.108403","url":null,"abstract":"<div><div>Japanese pine sawyer beetle (JPSB), <em>Monochamus alternatus</em> Hope, is a vector of the pine wilt nematode that causes pine wilting. Chemicals have been used to control JPSB, but they often cause environmental pollution and insect resistance. Alternatively, <em>Beauveria bassiana</em> ERL836 could be used to control JPSB and RNA-seq of the full body of JPSB was conducted to investigate host defense mechanisms. However, little interest was given to the defense mechanisms of the JPSB fat body which is a key organ of host defense and energy metabolism. ERL836 showed high insecticidal activity against JPSB adults and active sporulation on the cadavers, which potentially enables active spreading to other JPSB populations. From the RNA-seq of infected JPSB fat body, genes encoding for oxidative phosphorylation for energy metabolism were up-regulated 2 days but finally down-regulated 4 days compared to non-treated control, suggesting a reduction of energy metabolism during fungal infection. Simultaneously in the immune response of the fat body, serine protease inhibitor (serpin) genes which adversely regulate host defense response were continuously up-regulated and consequently most immune response were suppressed. The JPSB serpins including Spn42 and SRPN2 were phylogenetically close to ERL836 serpins. In fungal pathogenesis, JPSB defense pathways were strongly suppressed with the over-expression of serpin genes, although energy metabolism pathways were down-regulated. This work suggests that active expression of fat body serpin genes is possibly related to the speedy fungal infection, which could create a more favorable environment for fungal infection. In the next work, factors inducing the expression of JPSB serpins need to be clarified and the roles of fungal serpins would be investigated.</div></div>","PeriodicalId":16296,"journal":{"name":"Journal of invertebrate pathology","volume":"213 ","pages":"Article 108403"},"PeriodicalIF":3.6,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144698841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrated taxonomy reveals three novel Ophiocordyceps species (Ophiocordycipitaceae) from China: Morphological convergence and host-specific adaptations in zombie-ant fungi","authors":"Yuhu Guan ,&nbsp;Dexiang Tang ,&nbsp;Qirui Li ,&nbsp;Chanhom Loinheuang ,&nbsp;Xu Zhang ,&nbsp;Yao Wang","doi":"10.1016/j.jip.2025.108400","DOIUrl":"10.1016/j.jip.2025.108400","url":null,"abstract":"<div><div>The genus<!--> <em>Ophiocordyceps</em> <!-->(Ophiocordycipitaceae, Ascomycota) is a globally distributed group of entomopathogenic fungi, renowned for its complex host interactions, including the “zombie-ant” phenomenon. Despite their ecological significance, taxonomic delineation within this genus remains challenging due to morphological convergence and cryptic speciation. This study describes three novel species of<!--> <em>Ophiocordyceps</em>—<em>O. jilinensis</em>,<!--> <em>O. zongqii</em>, and<!--> <em>O. pseudobifertilis</em>—discovered during mycological surveys in subtropical and temperate forests of China. The species were identified through integrated morphological characterization and multilocus phylogenetic analyses (SSU, LSU,<!--> <em>TEF1α</em>,<!--> <em>RPB1</em>, and<!--> <em>RPB2</em>).<!--> <em>Ophiocordyceps jilinensis</em>, parasitizing Curculionidae, exhibits distinct phialide and conidial morphology, forming a unique sub-clade within the<!--> <em>Hirsutella</em> <!-->clade.<!--> <em>Ophiocordyceps zongqii</em> <!-->and<!--> <em>O. pseudobifertilis</em>, associated with<!--> <em>Polyrhachis</em> <!-->ants, cluster within the<!--> <em>O. unilateralis</em> <!-->complex but differ in stromatal structure and asexual morphotypes. Phylogenetic results strongly support their classification as new species, highlighting the importance of molecular tools in resolving cryptic diversity. The study also discusses host specificity, behavioral manipulation, and ecological adaptations of these fungi, contributing to the understanding of<!--> <em>Ophiocordyceps</em> <!-->evolution and host-pathogen dynamics. Specimens were deposited in the Guizhou Medical University Mycological Herbarium (GMB), with ex-type cultures preserved for further research. This work underscores the need for continued exploration of fungal diversity to elucidate evolutionary relationships and ecological roles in natural ecosystems.</div></div>","PeriodicalId":16296,"journal":{"name":"Journal of invertebrate pathology","volume":"212 ","pages":"Article 108400"},"PeriodicalIF":3.6,"publicationDate":"2025-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144632121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First description of Vibrio ostreicida as putative causal agent of disease in Mediterranean mussel (Mytilus galloprovincialis) and development of a PCR protocol for its rapid diagnosis","authors":"Jose R. Lopez ,&nbsp;Martina Leonessi ,&nbsp;Margarita Fernandez-Tejedor ,&nbsp;Manon Auguste ,&nbsp;Lapo Doni ,&nbsp;Yanis Cruz-Quintana ,&nbsp;Emanuele Bosi ,&nbsp;Luigi Vezzulli ,&nbsp;Karl Andree ,&nbsp;Laura Canesi ,&nbsp;Dolors Furones","doi":"10.1016/j.jip.2025.108399","DOIUrl":"10.1016/j.jip.2025.108399","url":null,"abstract":"<div><div>In April 2022, mussels (<em>Mytilus galloprovincialis</em>) cultivated in the Ebro River delta (Spain) were affected by a mortality episode, involving 25 % of individuals, observed at a water temperature of 18 °C. Mussel samples from this site (3 M) were analysed for the presence of potentially pathogenic bacteria, in parallel with those obtained from an area where no mortality was reported (3 N). From all samples, a total of 113 bacterial isolates were obtained. When subjected to ERIC-PCR, the obtained band patterns showed a distinct profile in the 3 M samples, covering 13 % of the isolates. The genotypic and phenotypic characterization of three representative isolates of this profile (r167, r172, r190) allowed their identification as <em>Vibrio ostreicida</em>. In addition, the complete genome of isolate r172 was sequenced to identify functional features of interest. Histological examination revealed bacterial colonies and tissue damage compatible with bacterial toxicity in 3 M samples. From a preliminary assessment of the virulence of the r172 isolate by mussel challenge via injection (9 × 10⁶ cfu/mussel), a mean mortality of 50 % was observed in infected animals at 5 days. Moreover, a specific PCR protocol was designed for <em>V. ostreicida</em> using the <em>gyrB</em> gene as a target, able to detect the pathogen from both pure cultures and from tissues. To our knowledge, this is the first evidence of the association of <em>V. ostreicida</em> with a mortality episode in cultured <em>M. galloprovincialis</em>. The PCR protocol developed will be useful for screening and diagnosis of this vibrio species in different matrices and to clarify its importance as shellfish possible pathogen.</div></div>","PeriodicalId":16296,"journal":{"name":"Journal of invertebrate pathology","volume":"212 ","pages":"Article 108399"},"PeriodicalIF":3.6,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The microspores of the parasitic dinoflagellate Hematodinium perezi infect crustacean hosts via waterborne transmission","authors":"Meng Li ,&nbsp;Qi Xue ,&nbsp;Jiayi Wang ,&nbsp;Ju Zhang ,&nbsp;Weixin Liu ,&nbsp;Qian Huang ,&nbsp;Lijun Hu ,&nbsp;Yan Liu ,&nbsp;Caiwen Li","doi":"10.1016/j.jip.2025.108396","DOIUrl":"10.1016/j.jip.2025.108396","url":null,"abstract":"<div><div>The parasitic dinoflagellate in <em>Hematodinium</em> genus is an important pathogen of economically important wild and cultured marine crustaceans worldwide. Numerous studies have been conducted to investigate its epidemics, life cycle history, and transmission route. Recent in-field and lab studies have validated the effectiveness of the waterborne transmission route and hypothesized that dinospores are the key life stage to infect the crustacean hosts via waterborne transmission. However, until now, there is still no direct evidence to establish the infectious roles of <em>Hematodinium</em> dinospores for crustaceans via waterborne transmission. In the present study, <em>Hematodinium</em> microspores naturally released from <em>Helice tientsinensis</em> were used to immerse healthy juvenile <em>Portunus trituberculatus</em> with different development stages (C2–C4 instars, C6–C7 instars) and adult <em>Helice tientsinensis</em>, respectively. <em>Hematodinium</em> presence and prevalence in the two crustacean species were detected by hemolymph smear assay, H&amp;E staining histopathology, and PCR analysis. The results showed that <em>Hematodinium</em> microspores successfully infected the two susceptible crustacean hosts, causing an overall <em>Hematodinium</em> prevalence of 40.4 % in <em>P. trituberculatus</em> (C2–C4 instars), 27.3 % in <em>P. trituberculatus</em> (C6–C7 instars), and 36.7 % in adult <em>Helice tientsinensis</em>, based on PCR analysis. The major findings in this study first provided direct and solid evidences to demonstrate that <em>Hematodinium</em> microspores are the key life stage to infect susceptible crustacean hosts via waterborne transmission. The physiological molting stage of crustacean hosts was found to be not associated with the infectious process of this parasite, while the growth stage of hosts was likely an important factor affecting the invasive and infectious process of <em>Hematodinium</em> microspores during waterborne transmission. The present study first established the waterborne transmission life stage of <em>Hematodinium</em> parasites, which will provide important information for effective prevention and control of <em>Hematodinium</em> epidemics in importantly economic marine crustaceans in future.</div></div>","PeriodicalId":16296,"journal":{"name":"Journal of invertebrate pathology","volume":"212 ","pages":"Article 108396"},"PeriodicalIF":3.6,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144595596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of gut bacteria isolated from Thai honey bees (Apis spp.) to control Nosema ceranae infection in the giant honey bee, Apis dorsata","authors":"Sanchai Naree ,&nbsp;Preeyaporn Ponguttha ,&nbsp;Rujira Ponkit ,&nbsp;Alexis Beaurepaire ,&nbsp;James D. Ellis ,&nbsp;Guntima Suwannapong","doi":"10.1016/j.jip.2025.108397","DOIUrl":"10.1016/j.jip.2025.108397","url":null,"abstract":"<div><div>Honey bee (<em>Apis</em> spp.) health is threatened by various pests and pathogens, including the microsporidia, <em>Nosema ceranae</em>. We investigated using two groups of beneficial gut bacteria isolated from Thai honey bees, <em>Apilactobacillus kunkeei</em> and <em>Bifidobacterium</em> sp., as a potential strategy to mitigate <em>N. ceranae</em> infections in the giant honey bee, <em>Apis dorsata</em>. For 24 h, newly emerged workers were individually fed 2 µL of a 50 % sucrose solution containing 2 × 10⁵ colony-forming units (CFU) of gut bacteria isolated from <em>A. cerana</em>, <em>A. dorsata</em>, <em>A. florea</em>, and <em>A. mellifera</em> workers. The bees were maintained in an incubator at 34 ± 2 °C and 55 ± 5 % RH. Subsequently, they were group-fed, 50 bees/group, with 500 μL of 50 % sucrose solution containing 10⁷<em>N. ceranae</em> spores. Bees fed <em>A. kunkeei</em> and <em>Bifidobacterium</em> sp. had significantly reduced mortality, <em>N. ceranae</em> infectivity, infection rate, and infection ratio compared to bees not fed the beneficial gut bacteria. Consumption of gut bacteria isolated from all four Thai honey bee species significantly increased the protein content of the hypopharyngeal glands of <em>A. dorsata</em> workers over that of bees not fed the bacteria. Collectively, these findings suggest that beneficial gut bacteria may serve as a promising strategy for protecting honey bee colonies from <em>Nosema</em> disease.</div></div>","PeriodicalId":16296,"journal":{"name":"Journal of invertebrate pathology","volume":"212 ","pages":"Article 108397"},"PeriodicalIF":3.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144579370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of two novel bacterial strains as the putative cause of black mouth disease in farmed Strongylocentrotus intermedius","authors":"Wanting Jiao ,&nbsp;Mingyu Xue ,&nbsp;Jinming Liu ,&nbsp;Linghui Yu ,&nbsp;Wenhong Mai ,&nbsp;Tanjun Zhao ,&nbsp;Yaoyao Zhan ,&nbsp;Yaqing Chang","doi":"10.1016/j.jip.2025.108398","DOIUrl":"10.1016/j.jip.2025.108398","url":null,"abstract":"<div><div>Black mouth disease (BMD) serves as the principal bacterial affliction of the cultivated sea urchin <em>Strongylocentrotus intermedius</em>, commonly breaking out in spring and winter. In January 2024 (winter), two predominant bacterial strains (SIBMPM04 and SIBMIT01) closely associated with BMD were isolated from the peristomial membrane and intestine of diseased <em>S. intermedius</em> from a farming area in the Yellow Sea of China. Characterization analyses, including Gram staining, morphology determination, artificial infection tests, and metabolic characterization, were then performed on SIBMPM04 and SIBMIT01. Both SIBMPM04 and SIBMIT01 belonged to the genus <em>Vibrio</em>, and 16S rRNA identification and phylogenetic analysis showed that SIBMPM04 shared a 98.68 % similarity with <em>Vibrio bathopelagicus</em> and that SIBMIT01 shared a 98.93 % similarity with <em>Vibrio atypicus</em>. Antimicrobial susceptibility tests indicated that both SIBMPM04 and SIBMIT01 were sensitive to chloramphenicol, florfenicol, imipenem, kanamycin, levofloxacin and polymyxin B. SIBMPM04 was sensitive to gentamycin and amikacin, and SIBMIT01 was sensitive to norfloxacin and sulfamethoxazole. Metabolic characterization data showed that SIBMPM04 and SIBMIT01 shared similar metabolic characteristics. Laboratory-based artificial infection tests showed that sea urchins infected with either SIBMPM04 or SIBMIT01 alone exhibited typical pathological symptoms of BMD in a dosage-dependent manner, and synergistic pathogenicity was observed when both bacterial strains were present. The observations from this study not only enrich information on these pathogens in sea urchins but also support the hypothesis that BMD may be induced by the synergistic action of multiple bacterial strains in sea urchins, leading to the rapid progression of disease symptoms.</div></div>","PeriodicalId":16296,"journal":{"name":"Journal of invertebrate pathology","volume":"212 ","pages":"Article 108398"},"PeriodicalIF":3.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144587759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Housing density affects the survivorship post infection of Drosophila melanogaster males in a pathogen dependent manner","authors":"Tsering Choton ,&nbsp;Manas Geeta Arun ,&nbsp;Harisankar Durga ,&nbsp;Pallavi Jaswal ,&nbsp;N.G. Prasad","doi":"10.1016/j.jip.2025.108395","DOIUrl":"10.1016/j.jip.2025.108395","url":null,"abstract":"<div><div>The impact of social interaction on physiology and behaviour has been widely studied in social insects, but less so in non-eusocial insects. Group housing can signal higher infection risk and reproductive competition, potentially leading to context-dependent trade-offs between reproductive versus immune investment. In this study, we housed <em>Drosophila melanogaster</em> males singly or in groups of two or sixteen for two days and assessed their post infection survival. We found that singly held males exhibited higher mortality post-infection with <em>Pseudomonas entomophila</em> compared to males housed in groups of sixteen. Males held singly or as pairs did not significantly differ in their mortality. However, there was no difference in mortality between the three groups when the pathogen was <em>Bacillus thuringiensis</em>. Singly held males showed elevated levels of <em>cat1</em>, <em>sod</em> and <em>puc</em> and lower levels of <em>rel</em>, indicating elevated stress levels and lower immunity in them. Environmental factors other than the housing density did not account for the difference in survivorship between singly held and group-held flies post-infection with <em>P. entomophila</em>. We observed no trade-off between reproductive investment and post-infection survivorship. Thus, our results show a complex interplay between social isolation, stress related mechanisms and immune function of a non-eusocial insect.</div></div>","PeriodicalId":16296,"journal":{"name":"Journal of invertebrate pathology","volume":"212 ","pages":"Article 108395"},"PeriodicalIF":3.6,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144584147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential negative effects of introduced or augmented entomopathogens on non-target predators and parasitoids","authors":"Mustapha Touray ,&nbsp;Derya Ulug ,&nbsp;Harun Cimen ,&nbsp;Sebnem H. Gulsen ,&nbsp;Fatma Bursali ,&nbsp;David Shapiro-Ilan ,&nbsp;Tariq M. Butt ,&nbsp;Selcuk Hazir","doi":"10.1016/j.jip.2025.108394","DOIUrl":"10.1016/j.jip.2025.108394","url":null,"abstract":"<div><div>This review examines the complex interactions between introduced or augmented entomopathogens (viruses, bacteria, fungi, and nematodes) and naturally occurring arthropod natural enemies (predators and parasitoids) within Integrated Pest Management programs. Entomopathogens are increasingly recognized as sustainable alternatives to chemical pesticides, which have detrimental effects on ecosystems and human health and are frequently banned before viable biocontrol alternatives are readily available. Consequently, biological control, a fundamental aspect of pest management, must expand to bridge this gap and safeguard adequate food production. This expansion necessitates a thorough understanding of potential negative impacts associated with biocontrol methods, even though such effects are generally anticipated to be less severe than those stemming from chemical control. The review synthesizes current knowledge on how entomopathogenic infections influence predator and parasitoid populations, focusing on infection, repellency, and attractancy effects across different pathogen groups, particularly concerning those feeding on or developing within infected hosts. Studies show varied impacts on predators, from tolerance to potential harm, with some predators even contributing to viral dispersal of entomopathogens, potential negative impacts warrant consideration. Combined applications of natural enemies can enhance pest control, but precise timing, concentration and formulations are crucial to maximize benefits and minimize harm to beneficial organisms. While entomopathogens can affect certain beneficial insects, the benefits outweigh the non-target impacts. A common thread across all groups is the need for further research, particularly long-term field studies under realistic conditions, to fully understand their interactions within complex ecosystems. By understanding these interactions, we can develop optimized pest control strategies that promote biodiversity and enhance the sustainability of agriculture, habitat management, and conservation.</div></div>","PeriodicalId":16296,"journal":{"name":"Journal of invertebrate pathology","volume":"212 ","pages":"Article 108394"},"PeriodicalIF":3.6,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144519160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}