Journal of lasers in medical sciences最新文献

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Photobiomodulation Therapy for Managing Motor and Sensory Dysfunctions Following Temporomandibular Joint Surgery: A Case Report. 光生物调节疗法用于治疗颞下颌关节手术后的运动和感觉功能障碍:病例报告。
IF 1.5
Journal of lasers in medical sciences Pub Date : 2023-12-28 eCollection Date: 2023-01-01 DOI: 10.34172/jlms.2023.67
Luiz Felipe Palma, Thales Dos Santos Porfírio, Rafael Verardi Serrano, Luana Campos, Luís Otávio Carvalho de Moraes
{"title":"Photobiomodulation Therapy for Managing Motor and Sensory Dysfunctions Following Temporomandibular Joint Surgery: A Case Report.","authors":"Luiz Felipe Palma, Thales Dos Santos Porfírio, Rafael Verardi Serrano, Luana Campos, Luís Otávio Carvalho de Moraes","doi":"10.34172/jlms.2023.67","DOIUrl":"10.34172/jlms.2023.67","url":null,"abstract":"<p><p><b>Introduction:</b> Surgical procedures involving the temporomandibular joint (TMJ) are frequently associated with nerve injuries and subsequent dysfunctions. Considering that traumatic peripheral nerve injuries may resolve slowly and their prognosis is generally unpredictable, the current study aimed to report a clinical case in which both motor (affecting the temporal and zygomatic branches of the facial nerve) and sensory dysfunctions (affecting the auriculotemporal nerve of the trigeminal nerve) following TMJ surgery were effectively treated by using photobiomodulation therapy (PBMT). <b>Case Report:</b> PBMT sessions, involving a total of 30 facial points, were administered twice a week for 10 weeks. The following parameters were utilized: wavelength of 808 nm, energy density of 75 J/cm<sup>2</sup>, power output of 100 mW, total energy of 3 J, and duration of 30 seconds per point. A considerable improvement in both facial asymmetry and muscle function was achieved within 5 weeks, along with a total restoration of cutaneous sensitivity. By the 10th week of PBMT, the facial movement dysfunction was completely resolved. <b>Conclusion:</b> According to the current case, PMBT seems to be an effective intervention to manage motor and sensory nerve dysfunctions following TMJ surgery.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"14 ","pages":"e67"},"PeriodicalIF":1.5,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10843219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139692040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Topographical Analysis of Human Enamel after Phosphoric Acid Etching and Er,Cr:YSGG Laser Irradiation. 磷酸蚀刻和 Er,Cr:YSGG 激光照射后人体珐琅质的地形分析
IF 1.5
Journal of lasers in medical sciences Pub Date : 2023-12-28 eCollection Date: 2023-01-01 DOI: 10.34172/jlms.2023.68
Saja Qasim Salman, Basima Mohammed Ali Hussein
{"title":"Topographical Analysis of Human Enamel after Phosphoric Acid Etching and Er,Cr:YSGG Laser Irradiation.","authors":"Saja Qasim Salman, Basima Mohammed Ali Hussein","doi":"10.34172/jlms.2023.68","DOIUrl":"10.34172/jlms.2023.68","url":null,"abstract":"<p><p><b>Introduction:</b> Dental hard and soft tissues have been successfully removed by using the Er,Cr:YSGG laser, but there is a controversy about using lasers over conventional tooth surface preparation for bonding aesthetic restoration. Surface roughness and wettability in response to Er,Cr:YSGG laser irradiation are essential properties for restoration longevity. <b>Methods:</b> Fifty-one intact human premolars removed in orthodontic treatment were included in this study and divided into three groups (n=17). The first group (G1) was the control without surface treatment, (G2) was treated with 37% phosphoric acid for 15 seconds, and (G3) was treated with the Er,Cr:YSGG laser using the following parameters: 2 W or 3 W at 20 Hz, 10% air and water ratio using the MZ6 laser tip. The standardization of laser irradiation was accomplished by a computerized numerical control unit. The surface of the samples was evaluated by using a light microscope, profilometer, atomic force microscopy (AFM), SEM, and wettability tests. <b>Results:</b> The SEM examination revealed that the lased enamel surface was clean, irregular, and devoid of a smear layer, while the acid etch surface was relatively smooth and covered with a smear layer. The surface roughness of the lased enamel surface was significantly higher than that of other groups, according to the results of the profilometer as well as the AFM tests. The wettability test showed that the lased enamel surface recorded a significant reduction in the contact angle in comparison to the other groups. <b>Conclusion:</b> It can be concluded that the Er,Cr:YSGG laser can be used as an alternative and safe method to the acid-etching technique for surface treatment.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"14 ","pages":"e68"},"PeriodicalIF":1.5,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10843234/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139692042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immune Response in Laser Tattoo Removal: A Systematic Review. 激光洗纹身的免疫反应:系统回顾
IF 1.5
Journal of lasers in medical sciences Pub Date : 2023-12-27 eCollection Date: 2023-01-01 DOI: 10.34172/jlms.2023.66
Arya Tjipta, Hafiz Ramadhan, Rahmi Amelia Lubis
{"title":"Immune Response in Laser Tattoo Removal: A Systematic Review.","authors":"Arya Tjipta, Hafiz Ramadhan, Rahmi Amelia Lubis","doi":"10.34172/jlms.2023.66","DOIUrl":"10.34172/jlms.2023.66","url":null,"abstract":"<p><p><b>Introduction:</b> The immune response to laser tattoo removal poses a significant challenge in its management, primarily due to its unpredictable nature, which can range from mild hypersensitivity reactions to severe anaphylaxis. Such responses can potentially hinder the effectiveness of laser tattoo removal procedures. Therefore, gaining a comprehensive understanding of the immune response to tattoo removal using laser techniques is of utmost importance to develop more efficient management strategies. This study aims to address this need by analyzing eight carefully selected articles obtained through a thorough literature review. <b>Methods:</b> To explore the immune response associated with laser techniques in tattoo removal, we employed a rigorous research methodology. A thorough literature review was conducted using reputable search engines such as Google Scholar, SagePub, and PubMed to collect relevant articles. Initially, 788 potential articles were identified through this process. Following meticulous scrutiny, only eight articles that met stringent inclusion criteria were selected for our study. This meticulous selection process ensures that the information presented here is derived from high-quality and pertinent research. <b>Results:</b> Based on the analysis of the eight selected articles, our findings illuminate the various immune responses that emerge following tattoo removal using laser techniques. These responses include hypersensitivity reactions, allergic manifestations, and, in certain instances, anaphylaxis. Hypersensitivity reactions typically manifested as erythema, edema, and pruritus, while allergic responses were observed in the form of urticaria. In summary, our study highlights that the immune response to laser tattoo removal primarily elicits hypersensitivity and, in some cases, anaphylaxis reactions. <b>Conclusion:</b> Our study underscores the significance of clinicians being vigilant regarding potential immune responses during laser tattoo removal. It is crucial to closely monitor patients to promptly address any adverse reactions. Further research holds the potential to enhance our understanding, paving the way for improved management strategies that can enhance patient safety and treatment success.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"14 ","pages":"e66"},"PeriodicalIF":1.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10843227/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139692039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring Intercellular Dynamics: Ultra-Weak Biophoton Emission as a Novel Indicator of Altered Cell Functions and Disease in Oligospermia Mice. 探索细胞间动力学:将超弱生物光子发射作为少精症小鼠细胞功能和疾病改变的新指标
IF 1.5
Journal of lasers in medical sciences Pub Date : 2023-12-26 eCollection Date: 2023-01-01 DOI: 10.34172/jlms.2023.65
Arefeh Aryan, Fakhroddin Aghajanpour, Masoomeh Dashtdar, Fatemeh Hejazi, Maryam Salimi, Azar Afshar, Reza Soltani, Ahad Hasan Seyed Hasani, Abbas Aliaghaei, Hojjat-Allah Abbaszadeh, Hasan Mahmoodi, Leila Zahedi, Mohammad-Amin Abdollahifar, Fatemeh Fadaei Fathabadi
{"title":"Exploring Intercellular Dynamics: Ultra-Weak Biophoton Emission as a Novel Indicator of Altered Cell Functions and Disease in Oligospermia Mice.","authors":"Arefeh Aryan, Fakhroddin Aghajanpour, Masoomeh Dashtdar, Fatemeh Hejazi, Maryam Salimi, Azar Afshar, Reza Soltani, Ahad Hasan Seyed Hasani, Abbas Aliaghaei, Hojjat-Allah Abbaszadeh, Hasan Mahmoodi, Leila Zahedi, Mohammad-Amin Abdollahifar, Fatemeh Fadaei Fathabadi","doi":"10.34172/jlms.2023.65","DOIUrl":"10.34172/jlms.2023.65","url":null,"abstract":"<p><p><b>Introduction:</b> Biophoton emission, the spontaneous release of photons from living cells, has emerged as an attractive field of research in the study of biological systems. Scientists have recently discovered that changes in biophoton emission could serve as potential indicators of pathological conditions. This intriguing phenomenon suggests that cells might communicate and interact with each other through the exchange of these faint but significant light signals. Therefore, the present study introduces intercellular relationships with biophoton release to detect normal and abnormal cell functions to further achieve cellular interactions by focusing on cell and cell arrangement in disease conditions. <b>Methods:</b> Twenty male mice were assigned to control and busulfan groups. Five weeks after the injection of busulfan, the testis was removed, and then the stereological techniques and TUNEL assay were applied to estimate the histopathology of the testis tissue sections. <b>Results:</b> The findings revealed that the ultra-weak biophoton emission in the control group was significantly lower than in the busulfan group. The oligospermia mice model showed that it significantly changed the spatial arrangement of testicular cells and notably decreased the testis volume, length of seminiferous tubules, and the number of testicular cells. The results of the TUNEL assay showed that the percentage of apoptotic cells significantly increased in the busulfan group. <b>Conclusion:</b> The ultra-weak biophoton emission from testis tissue was reduced in oligospermia mice. As a result, the decline of ultra-weak biophoton can indicate a change in cell arrangement, a decrease in intercellular interaction, and eventually disease.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"14 ","pages":"e65"},"PeriodicalIF":1.5,"publicationDate":"2023-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10843233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139692038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Doppler Finding, Cardiovascular Function Assessment, and Fetuses' Survival Following the Fetoscopic Laser in Twin-to-Twin Transfusion Syndrome. 双胎输血综合征胎儿镜激光术后的多普勒检查结果、心血管功能评估和胎儿存活率
IF 1.5
Journal of lasers in medical sciences Pub Date : 2023-12-26 eCollection Date: 2023-01-01 DOI: 10.34172/jlms.2023.64
Tahmineh Ezazi Bojnordi, Laleh Eslamian, Vajiheh Marsoosi, Alireza Golbabaei, Mehrdad Sheikh Vatan, Alireza A Shamshirsaz, Nasim Eshraghi, Marjan Ghaemi
{"title":"Doppler Finding, Cardiovascular Function Assessment, and Fetuses' Survival Following the Fetoscopic Laser in Twin-to-Twin Transfusion Syndrome.","authors":"Tahmineh Ezazi Bojnordi, Laleh Eslamian, Vajiheh Marsoosi, Alireza Golbabaei, Mehrdad Sheikh Vatan, Alireza A Shamshirsaz, Nasim Eshraghi, Marjan Ghaemi","doi":"10.34172/jlms.2023.64","DOIUrl":"10.34172/jlms.2023.64","url":null,"abstract":"<p><p><b>Introduction:</b> This study aimed to evaluate the effectiveness of selective laser photocoagulation of communicating vessels (SLPCV) on cardiac function in twins with twin-to-twin transfusion syndrome (TTTS). <b>Methods:</b> This retrospective cohort study evaluated 178 women with twin pregnancies complicated with TTTS and scheduled for SLPCV between 16 and 26 weeks of gestation. The severity of TTTS was determined by Quintero staging and the severity of cardiovascular disorders by the CHOP (Children's Hospital of Philadelphia) score. Patient survival was evaluated through a one-month-after-birth follow-up of fetuses. <b>Results:</b> The study revealed significant improvements in Doppler indices in both donors and recipients after SLPCV. The CHOP score also significantly decreased after the intervention. One-month-after-birth survival rates were 55.1% in donors and 56.7% in recipients. Some Doppler indexes of fetuses before SLPCV could predict survival until one month after birth. <b>Conclusion:</b> The study suggests that SLPCV can improve cardiac function in fetuses with TTTS and that some Doppler indexes can predict survival outcomes. Additionally, the severity of TTTS can be a powerful indicator of the severity of cardiovascular complications.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"14 ","pages":"e64"},"PeriodicalIF":1.5,"publicationDate":"2023-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10843211/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139692036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Invariant point message passing for protein side chain packing. 蛋白质侧链包装的不变点信息传递
Journal of lasers in medical sciences Pub Date : 2023-12-21 DOI: 10.1101/2023.08.03.551328
Nicholas Z Randolph, Brian Kuhlman
{"title":"Invariant point message passing for protein side chain packing.","authors":"Nicholas Z Randolph, Brian Kuhlman","doi":"10.1101/2023.08.03.551328","DOIUrl":"10.1101/2023.08.03.551328","url":null,"abstract":"<p><p>Protein side chain packing (PSCP) is a fundamental problem in the field of protein engineering, as high-confidence and low-energy conformations of amino acid side chains are crucial for understanding (and designing) protein folding, protein-protein interactions, and protein-ligand interactions. Traditional PSCP methods (such as the Rosetta Packer) often rely on a library of discrete side chain conformations, or rotamers, and a forcefield to guide the structure to low-energy conformations. Recently, deep learning (DL) based methods (such as DLPacker, AttnPacker, and DiffPack) have demonstrated state-of-the-art predictions and speed in the PSCP task. Building off the success of geometric graph neural networks for protein modeling, we present the Protein Invariant Point Packer (PIPPack) which effectively processes local structural and sequence information to produce realistic, idealized side chain coordinates using <i>χ</i>-angle distribution predictions and geometry-aware invariant point message passing (IPMP). On a test set of ~1,400 high-quality protein chains, PIPPack is highly competitive with other state-of-the-art PSCP methods in rotamer recovery and per-residue RMSD but is significantly faster.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"6 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10769188/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90050848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the Diode Laser Wavelengths 445 nm and 810 nm in Gingival Depigmentation – A Clinical Evaluation 二极管激光波长 445 纳米和 810 纳米在牙龈色素沉着中的应用比较 - 临床评估
IF 1.5
Journal of lasers in medical sciences Pub Date : 2023-12-19 DOI: 10.34172/jlms.2023.63
Seyed Masoud Mojahedi Nasab, Matthias Frentzen, Andreas Mayr, Somayeh Rahmani, F. Anbari, J. Meister, Saranaz Azari-Marhabi, Deniz Mojahedi Nasab
{"title":"Comparison of the Diode Laser Wavelengths 445 nm and 810 nm in Gingival Depigmentation – A Clinical Evaluation","authors":"Seyed Masoud Mojahedi Nasab, Matthias Frentzen, Andreas Mayr, Somayeh Rahmani, F. Anbari, J. Meister, Saranaz Azari-Marhabi, Deniz Mojahedi Nasab","doi":"10.34172/jlms.2023.63","DOIUrl":"https://doi.org/10.34172/jlms.2023.63","url":null,"abstract":"Introduction: Nowadays, esthetic appearance plays an important role in the field of dentistry. Discolorations and pigmentations of the gingiva reduce the appearance of a healthy-looking smile. On this occasion, the use of lasers shows a promising approach for a fast and non-aggressive treatment in this field. Different laser wavelengths are being used for gingival depigmentation this clinical study aimed to investigate the effect of the novel laser wavelength (445 nm) in this field and compare it with an 810 nm diode laser. Methods: Two diode laser wavelengths (445 nm and 810 nm) were used for depigmentation. The laser output power chosen was 1 W. An optical fiber with a diameter of 400 µm was used. 21 patients with pigmented gingiva were selected. Depigmentation was carried out in a split-mouth design for a direct comparison of the clinical effect. Outcomes were documented by photograph after one month and six months of follow-up. Results: For each wavelength, 21 volunteers evaluated 21 clinical cases of depigmentation, which means that 441 comparisons were carried out in total regarding the color change from brownish to pinkish. A 100% clarification was achieved for 445 nm. In the 810 nm group, the color change in 44 of 441 cases (10%) could not be clearly identified. No statistically significant difference in pain experience was reported for both laser treatments. Conclusion: The clinical evaluation showed that within the limitations of this study, most of the clinical outcome parameters were highly acceptable by the patients due to mild pain and discomfort for both laser systems.","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"525 ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139171904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the Effect of Phosphoric Acid or Er: YAG Laser on the Shear Bond Strength of Orthodontic Brackets to Enamel Surfaces Followed by 980-Laser Assisted Bleaching: An In Vitro Study 评估磷酸或 Er: YAG 激光对 980 激光辅助漂白后正畸托槽与珐琅质表面的剪切粘接强度的影响:一项体外研究
IF 1.5
Journal of lasers in medical sciences Pub Date : 2023-12-13 DOI: 10.34172/jlms.2023.62
Mohammad Oladzad, N. Chiniforush, R. Bahrami, A. Mirhashemi
{"title":"Evaluation of the Effect of Phosphoric Acid or Er: YAG Laser on the Shear Bond Strength of Orthodontic Brackets to Enamel Surfaces Followed by 980-Laser Assisted Bleaching: An In Vitro Study","authors":"Mohammad Oladzad, N. Chiniforush, R. Bahrami, A. Mirhashemi","doi":"10.34172/jlms.2023.62","DOIUrl":"https://doi.org/10.34172/jlms.2023.62","url":null,"abstract":"Introduction: The residual oxygen remained on tooth surface after bleaching may interfere with adhesion of brackets to enamel surface. This study aimed to evaluate the influence of phosphoric acid and Er: YAG laser as an etching technique on the shear bond strength (SBS) of orthodontic brackets to enamel surfaces after 980-laser-assisted bleaching. Method: A total of 84 human premolars were recruited in the present study. Samples were divided into 6 groups including conventional bleaching with conventional etching, conventional bleaching with Er: YAG laser etching, laser-assisted bleaching with conventional etching, and Laser-assisted bleaching with Er: YAG laser etching, without bleaching with traditional etching, and without bleaching+Er: YAG laser etching. Following thermocycling, the debonding of brackets was conducted using a universal testing machine. Scanning electron microscope (SEM) microscope evaluation and adhesive remnant index (ARI) scores were assessed. The comparison of SBS values between groups was carried out by means of a one-way analysis of variance, followed by post-hoc tests. Results: The non-bleaching with conventional etching group showed the highest SBS mean value (23.45±5.16 MPa), whereas the conventional bleaching with conventional etching group represented the lowest SBS mean value (8.8±3.83 MPa). In all groups, the most common type of failure was classified as either score 1 or score 2. No significant difference was observed in terms of SBS mean between the groups (P=0.165); however, the average SBS of bleached teeth was significantly lower, compared to the non-bleached group (P=0.000). Honeycomb structure and porosity were observed following Er: YAG laser etching on the tooth surface. Conclusion: Increased bond strength of brackets was observed in bleached teeth following Er: YAG laser etching. Therefore, if necessary, bond the brackets on the same day of bleaching will be done, the application of Er:YAG laser as etching technique will can be recommended.","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"223 4","pages":""},"PeriodicalIF":1.5,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139181253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Histologic Evaluation of Effect of Three Wavelengths of Diode Laser on Human Gingival Margins 三种波长二极管激光对人类牙龈边缘影响的组织学评估
IF 1.5
Journal of lasers in medical sciences Pub Date : 2023-12-11 DOI: 10.34172/jlms.2023.61
Pilar Rocío Blanco Flórez, Helida Helena Avendaño Maz, Josep Arnabat Domínguez, Antonio Jesús España Tost, Jennifer Orozco Páez
{"title":"Histologic Evaluation of Effect of Three Wavelengths of Diode Laser on Human Gingival Margins","authors":"Pilar Rocío Blanco Flórez, Helida Helena Avendaño Maz, Josep Arnabat Domínguez, Antonio Jesús España Tost, Jennifer Orozco Páez","doi":"10.34172/jlms.2023.61","DOIUrl":"https://doi.org/10.34172/jlms.2023.61","url":null,"abstract":"Introduction: Available evidence suggests that the response of the intervened tissue is directly linked to the effects generated by the cutting instrument used. To determine the histological findings in gingival tissue margins excised through gingivectomies performed using 450 nm, 940 nm, and 980 nm diode lasers. The present study aimed to determine the histological findings in gingival tissue margins excised through gingivectomies performed using 450 nm, 940 nm, and 980 nm diode lasers. Methods: Gingival tissue samples were collected from 30 patients who had undergone gingivectomy procedures. Each study group comprised 10 patients who willingly provided their samples after providing informed consent. The visualization of histological findings was facilitated through Hematoxylin-Eosin staining. Additionally, variables related to pain and hemostasis were assessed during the intraoperative period. Results: The incision quality was categorized as irregular across all three wavelengths. Histological examination of the epithelial tissue revealed the absence of carbonization and the preservation of cell morphology in over 50% of the resection margin in samples obtained with the 450 nm and 940 nm wavelengths. In the connective tissue, observations included carbonization, collagen coagulation, and basophilia, with the 980 nm wavelength demonstrating the highest percentage of samples displaying collagen coagulation in more than 50% of the resection margin. Conversely, the 450 nm wavelength exhibited the highest degree of preservation of the fibroblast structure. Conclusion: Based on a comprehensive analysis of the study results, it can be inferred that the 450nm and 940nm wavelength lasers tend to produce less thermal damage and better cell preservation when compared to the 980nm wavelength.","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"62 5","pages":""},"PeriodicalIF":1.5,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139183708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy Evaluation of Human Skin Treatment with Photodynamic Therapy in Actinic Keratoses Patients. 用光动力疗法治疗人类皮肤角化病的疗效评估。
IF 1.5
Journal of lasers in medical sciences Pub Date : 2023-11-29 eCollection Date: 2023-01-01 DOI: 10.34172/jlms.2023.60
Zahra Razzaghi, Babak Arjmand, Maryam Hamzeloo-Moghadam, Mostafa Rezaei Tavirani, Mona Zamanian Azodi
{"title":"Efficacy Evaluation of Human Skin Treatment with Photodynamic Therapy in Actinic Keratoses Patients.","authors":"Zahra Razzaghi, Babak Arjmand, Maryam Hamzeloo-Moghadam, Mostafa Rezaei Tavirani, Mona Zamanian Azodi","doi":"10.34172/jlms.2023.60","DOIUrl":"https://doi.org/10.34172/jlms.2023.60","url":null,"abstract":"<p><p><b>Introduction:</b> Photodynamic therapy (PDT) is a combined method of light and light-activated chemicals that are called photosensitizers (PSs). PDT is recommended as a high cure rate method with fewer side effects and a noninvasive tool to treat cancer. This study aimed to evaluate PDT efficacy as a therapeutic method against actinic keratoses in patients via protein-protein interaction (PPI) network analysis by using the gene expression profiles of Gene Expression Omnibus (GEO). <b>Methods:</b> Twenty-one gene expression profiles were extracted from GEO and analyzed by GEO2R to determine the significant differentially expressed genes (DEGs). The significant DEGs were included in PPI networks via Cytoscape software. The networks were analyzed by the \"Network Analyzer\", and the elements of the main connected components were assessed. <b>Results:</b> There were three main connected components for the compared sets of the gene expression profiles including the lesional region of skin before (Before set) and after (After set) PDT versus healthy (healthy set) skin and before versus after. The before-health comparison showed a partial similarity with the After-Healthy assessment. The before-after evaluation indicated that there were not considerable differences between the gene expression profile of the lesional region before and after PDT. <b>Conclusion:</b> In conclusion, PDT was unable to return the gene expression pattern of the actinic keratoses skin to a healthy condition completely.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"14 ","pages":"e60"},"PeriodicalIF":1.5,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10746884/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139032406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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