Journal of Medical Imaging and Radiation Oncology最新文献

{"title":"Overview of cardiac toxicity from radiation therapy.","authors":"Vicky Chin, Robert N Finnegan, Paul Keall, James Otton, Geoff P Delaney, Shalini K Vinod","doi":"10.1111/1754-9485.13757","DOIUrl":"10.1111/1754-9485.13757","url":null,"abstract":"<p><p>Radiotherapy is an essential part of treatment for many patients with thoracic cancers. However, proximity of the heart to tumour targets can lead to cardiac side effects, with studies demonstrating link between cardiac radiation dose and adverse outcomes. Although reducing cardiac dose can reduce associated risks, most cardiac constraint recommendations in clinical use are generally based on dose to the whole heart, as dose assessment at cardiac substructure levels on individual patients has been limited historically. Furthermore, estimation of an individual's cardiac risk is complex and multifactorial, which includes radiation dose alongside baseline risk factors, and the impact of systemic therapies. This review gives an overview of the epidemiological impact of cancer and cardiac disease, risk factors contributing to radiation-related cardiotoxicity, the evidence for cardiac side effects and future directions in cardiotoxicity research. A better understanding of the interactions between risk factors, balancing treatment benefit versus toxicity and the ongoing management of cardiac risk is essential for optimal clinical care. The emerging field of cardio-oncology is thus a multidisciplinary collaborative effort to enable better understanding of cardiac risks and outcomes for better-informed patient management decisions.</p>","PeriodicalId":16218,"journal":{"name":"Journal of Medical Imaging and Radiation Oncology","volume":" ","pages":"987-1000"},"PeriodicalIF":2.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11686457/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142289322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FDG PET/CT in large vessel vasculitis.","authors":"Karan Bir Singh, Katherine Nguyen, Anthony Sammel, Eva A Wegner, Ivan Ho Shon","doi":"10.1111/1754-9485.13800","DOIUrl":"10.1111/1754-9485.13800","url":null,"abstract":"<p><p>Large vessel vasculitides (LVV) such as giant cell arteritis, Takayasu arteritis and aortitis/periaortitis are characterised by immune-mediated inflammation of medium to large arteries. Clinical disease manifestations can be non-specific and diagnostic imaging plays an important role in the diagnostic pathway. In recent years, FDG PET/CT has proven to be a powerful metabolic tool that can provide a wholed body, non-invasive assessment of vascular inflammation. This review outlines the clinical features of large vessel vasculitis and the closely related entity of polymyalgia rheumatica, summarises the evidence for FDG PET/CT in the assessment of these conditions, and provides guidance for patient preparation, image acquisition and interpretation.</p>","PeriodicalId":16218,"journal":{"name":"Journal of Medical Imaging and Radiation Oncology","volume":" ","pages":"881-892"},"PeriodicalIF":2.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142502088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IRSA ASM 2024 Abstract.","authors":"","doi":"10.1111/1754-9485.13759","DOIUrl":"10.1111/1754-9485.13759","url":null,"abstract":"","PeriodicalId":16218,"journal":{"name":"Journal of Medical Imaging and Radiation Oncology","volume":" ","pages":"e2"},"PeriodicalIF":2.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142381022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardio-oncology and radiation oncology: How collaboration between cardiologists and oncologists can be realised in radiation oncology.","authors":"Samuel Birch, James Otton","doi":"10.1111/1754-9485.13724","DOIUrl":"10.1111/1754-9485.13724","url":null,"abstract":"<p><p>Increased survivorship, improvements in cancer treatments, and the potential for cardiac side effects from cancer treatments have resulted in increased collaboration between oncologists and cardiologists and the development of cardio-oncology clinics. This collaboration is important given its role in ensuring greater patient satisfaction, aiding teams of clinicians in making complex treatment decision, and ensuring cardiac complications are diagnosed at an early stage. The particularities of implementing this collaboration in the field of radiation oncology and how this setting is different from other areas of cardio-oncology have not been well detailed in the literature. This paper will discuss what is currently understood about the need for and role of cardio-oncology and what a cardio-oncology services involves, with a particular emphasis on patient and clinician needs in the field of radiation oncology. The literature and recent guidelines do advocate for a detailed baseline assessment of cancer patients undergoing radiotherapy, especially patients with treatment or patient risk factors that increase their risk of cancer-therapy related cardiotoxicity. Advancements in cardiac imaging techniques will be discussed as these may help to diagnose cardiac side effects of certain cancer treatments, including radiotherapy, at an early stage. A multi-disciplinary and collaborative approach is well received by patients and such an approach, guided by the aim of maintaining a patient's cancer treatment wherever possible, should be the cornerstone of cardio-oncology clinics regardless of the patient's treatment regime.</p>","PeriodicalId":16218,"journal":{"name":"Journal of Medical Imaging and Radiation Oncology","volume":" ","pages":"962-973"},"PeriodicalIF":2.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141317547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The sustainability impacts of a web-based outpatient booking application.","authors":"Melissa Yeo, Kane Nicholls, Pey Ling Shum, Hamed Asadi, Natalie Yang","doi":"10.1111/1754-9485.13815","DOIUrl":"https://doi.org/10.1111/1754-9485.13815","url":null,"abstract":"<p><strong>Background: </strong>Climate change is a critical global issue, impacting ecosystems, economies and communities worldwide. The shift from paper-based to digital systems is becoming increasingly prevalent across industries, with downstream positive impacts on sustainability. In 2020, Austin Health, a public tertiary hospital in Victoria, Australia, adopted a web-based outpatient booking application, which succeeded the prior paper-based system. The application served as an integrated platform for administrative staff to access various Austin Information Technology platforms and replaced previous mail-based outpatient appointment notifications with Short Message Service-based notifications. This study aimed to assess the environmental impact and organisation-wide economic cost of a web-based outpatient booking application compared to the prior paper-based system across the same time period.</p><p><strong>Methods: </strong>A retrospective environmental and economic assessment was conducted for both the web-based booking application and the paper-based system. The evaluation covered 36,925 outpatient diagnostic imaging studies - including CT, MRI, ultrasound and mammography - performed at Austin Health from 1st July 2023 until 30th June 2024. The environmental impact was assessed by calculating the expected carbon dioxide equivalent (CO₂e) emissions produced by each system. The economic cost analysis was conducted from the perspective of the hospital and included the direct costs of labour and materials/consumables.</p><p><strong>Results: </strong>CO₂e emissions were significantly reduced using the web-based outpatient booking application compared to the prior paper-based system (38.5 tonnes compared to 0.002 tonnes), predominantly attributable to the elimination of postage-related fuel emissions (27.7 tonnes). The estimated net operating cost savings across the year was at least AUD 175,000 (in 2024 Australian Dollars, adjusted for inflation). This was primarily due to labour savings from the elimination of workflow inefficiencies (at least 2342 h saved) amounting to at least AUD 85,272 in salary, followed by savings from eliminated pathology tests (AUD 57,422) and postage costs (AUD 55,193).</p><p><strong>Conclusion: </strong>The adoption of the web-based outpatient booking application led to a substantial reduction in carbon emissions and operating costs, alongside enhanced operational efficiency and productivity. These benefits are anticipated to be enduring, especially in the face of an ever-increasing demand for medical imaging services.</p>","PeriodicalId":16218,"journal":{"name":"Journal of Medical Imaging and Radiation Oncology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142729676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visual perceptual artefacts in cardiothoracic imaging: Implications for diagnostic accuracy and strategies for mitigation.","authors":"Thomas P Stirrat, Michael Chang, Anushka Desai, Shankar Thiru, Daniel T Chen, Joseph Waller, Aws Kamona, Muhammad Umair","doi":"10.1111/1754-9485.13810","DOIUrl":"https://doi.org/10.1111/1754-9485.13810","url":null,"abstract":"<p><p>Visual perceptual artefacts are distortions or illusions in medical image interpretation arising from the human visual system rather than hardware or imaging acquisition processes. These artefacts, emerging at various visual processing stages, such as the retina, visual pathways, visual cortex, and cognitive interpretation stages, impact the interpretation of cardiothoracic images. This review discusses artefacts including Mach bands, Dark Rim, Background Effects, Ambiguous Figures, Subjective Contours, and the Parallax Effect. A thorough literature search was conducted using PubMed and Google Scholar. Search terms included 'visual perceptual artifacts', 'cardiothoracic imaging', 'Mach bands', 'dark rim artifact', 'stress cardiac MRI', and 'radiology visual illusions'. Inclusion criteria encompassed studies focusing on visual perceptual artefacts in cardiothoracic imaging published in peer-reviewed journals. Studies not addressing visual perceptual artefacts or those focusing on imaging technology, hardware, or software-related artefacts were excluded. Duplicate studies were removed, and a final selection of 32 studies was analysed. Several key visual perceptual artefacts relevant to cardiothoracic imaging were identified. Mach bands, caused by lateral inhibition in the retina, create false contrasts at object boundaries, potentially mimicking pathologies such as fractures or pneumothoraces. The dark rim artefact observed on stress cardiac MRI, resulting from Gibbs ringing or truncation artefacts, can simulate perfusion defects and complicate diagnosis. Lateral inhibition can possibly accentuate the appearance of the dark rim artefact. Artefacts also fall under illusions of sensation, perception, and image formation. These illusions present both risks and benefits to diagnostic radiology. Recognizing visual perceptual artefacts is crucial for improving diagnostic accuracy and developing strategies to mitigate their impact. A comprehensive understanding and training on these artefacts are essential for radiologists to enhance interpretive skills, reduce diagnostic errors, and ultimately improve patient care in radiology.</p>","PeriodicalId":16218,"journal":{"name":"Journal of Medical Imaging and Radiation Oncology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142729146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of ultra-low-dose CT with tin filter for craniosynostosis.","authors":"Wilson Tao, Robert Goetti","doi":"10.1111/1754-9485.13812","DOIUrl":"https://doi.org/10.1111/1754-9485.13812","url":null,"abstract":"<p><strong>Introduction: </strong>CT has replaced skull radiography as the gold standard for assessment of craniosynostosis in children. To minimise the risks of ionising radiation in this radiosensitive population, low-dose CT protocols are increasingly being adopted. This study evaluates the effectiveness of an ultra-low-dose CT protocol with a tin filter in reducing radiation exposure whilst maintaining diagnostic quality for craniosynostosis, and its utility in the evaluation of other findings not appreciable on skull radiography.</p><p><strong>Methods: </strong>Twenty-seven patients who underwent ultra-low-dose CT for craniosynostosis were compared with an age-matched control group who received standard-dose CT for indications other than craniosynostosis. Differences in radiation dosimetry and quantitative image quality parameters were analysed using independent two-tailed t-tests. Radiologist reports were also examined for the frequency of other incidental radiological findings.</p><p><strong>Results: </strong>Mean effective dose for the 27 ultra-low-dose CT scans was 0.14 mSv, a 92% reduction compared with the control group. Image quality, measured by contrast-to-noise ratio, was significantly lower in the ultra-low-dose scans compared with the standard-dose scans; however, all scans were diagnostic for detecting or excluding craniosynostosis. Hydrocephalus was able to be ruled out in all 27 ultra-low-dose scans.</p><p><strong>Conclusion: </strong>Ultra-low-dose CT with a tin filter allows for the diagnosis of craniosynostosis with a 92% dose reduction compared with the standard CT protocol. Despite lower image quality with the ultra-low-dose protocol when compared to standard CT, all 27 scans were adequate for craniosynostosis diagnosis. Additionally, it allowed for the assessment of other relevant findings not appreciable with skull radiography, highlighting its advantages as the new clinical standard for craniosynostosis assessment.</p>","PeriodicalId":16218,"journal":{"name":"Journal of Medical Imaging and Radiation Oncology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142729675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paraganglioma and phaeochromocytoma in adult Fontan patients.","authors":"Stephanie Bm Tan, Maria Luz Garagiola, Xiaoyang Liu, Tae Kyoung Kim, Ciara Mo Brien","doi":"10.1111/1754-9485.13809","DOIUrl":"https://doi.org/10.1111/1754-9485.13809","url":null,"abstract":"<p><strong>Introduction: </strong>The purpose of this study was to address the gap in knowledge in the incidence, presentation and imaging features of PPGL in Fontan patients. It has been hypothesised in the literature that Fontan circulation patients have an increased incidence of these tumours. This study is the largest cohort of adult Fontan patients in North America. The Fontan procedure is a palliative procedure for single ventricle congenital heart disease where the systemic venous return is directed into the pulmonary circulation. Fontan patients are at increased risk of developing several extracardiac complications including phaeochromocytoma and paraganglioma (PPGL).</p><p><strong>Methods: </strong>This retrospective single-centre study includes all adult patients who were treated between 1 September 2015 and 1 September 2022 in a tertiary referral centre for adult congenital heart disease. Imaging and electronic medical records were retrospectively searched for the presence of PPGL.</p><p><strong>Results: </strong>Five hundred and forty-seven Fontan patients were included in the study. Three patients had PPGL with an incidence of 0.5%. Two patients were diagnosed with paraganglioma and one with phaeochromocytoma. All patients were female. Median age of Fontan procedure was 1.8 years (range: 1.75-27 years). Median age of PPGL diagnosis was 19 years (range: 12-39 years). Median time from Fontan operation to diagnosis of PPGL was 12 years (range: 10.3-17.2 years).</p><p><strong>Conclusion: </strong>Fontan patients are at increased risk of PPGL. Clinically, the diagnosis of PPGL is challenging as symptoms and serum markers can be confounding in this population; however, the imaging features of PPGL remain typical making the role of the radiologist crucial.</p>","PeriodicalId":16218,"journal":{"name":"Journal of Medical Imaging and Radiation Oncology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142622029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Publication output of RANZCR radiation oncologists in 2022-23.","authors":"Daniel Roos, Lisa Milner, Therese Kang, Emma Quinn, Wee Loon Ong","doi":"10.1111/1754-9485.13807","DOIUrl":"https://doi.org/10.1111/1754-9485.13807","url":null,"abstract":"<p><strong>Introduction: </strong>The purpose of this work was to determine the current publication output of Royal Australian and New Zealand College of Radiologists radiation oncologists (ROs) to serve as a baseline contributing to future assessment of the effectiveness of the College's Research Action Plan 2024-26.</p><p><strong>Methods: </strong>An online survey was sent to all ROs in the College's member database in March-April 2024 requesting a list of publications between 2022 and 2023. A PubMed search was performed to cross-check the self-reported publications. Given the low response rate (8%), an additional PubMed search was performed for the non-responders. The primary outcomes were publication proportions and rates, and the secondary outcomes were demographic correlates (gender, country, seniority).</p><p><strong>Results: </strong>There were 536 eligible ROs (56% males; 80% practicing in Australia; median 12.4 years post-Fellowship) with 1,012 unique publications identified. The proportions of ROs with at least one publication in any-, first- and last-author positions averaged 45%, 15% and 17% per year, respectively. On multivariable analysis, there were statistically significant differences in publications by seniority (higher proportions of last-authorships but lower proportions of first-authorships, for those ≥5 years post-Fellowship) and by country (lower any-, and last-authorships for New Zealand [NZ] than Australia or Singapore). The mean numbers of any-, first- and last-authorships were 1.6, 0.18 and 0.29 per RO per year, respectively. On multivariable analysis, there were statistically significant differences by gender (males had more any-, and first-authorships), seniority (senior ROs had more last-authorships but less first-authorships) and country (lower numbers of any-, and last-authorships for New Zealand).</p><p><strong>Conclusion: </strong>This organization-wide study provides comprehensive baseline RO publication data and identifies opportunities for the College to further address correlated disparities.</p>","PeriodicalId":16218,"journal":{"name":"Journal of Medical Imaging and Radiation Oncology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142622031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiotherapy for node-positive prostate cancer in the PSMA-PET era: The need for prospective clinical trials.","authors":"Wee Loon Ong, Therese Min Jung Kang, Andrew Loblaw","doi":"10.1111/1754-9485.13806","DOIUrl":"https://doi.org/10.1111/1754-9485.13806","url":null,"abstract":"","PeriodicalId":16218,"journal":{"name":"Journal of Medical Imaging and Radiation Oncology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142621984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}