Journal of Medical Imaging and Radiation Oncology最新文献

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ANZSNR 2025 ASM Abstracts. ANZSNR 2025 ASM摘要。
IF 2.2 4区 医学
Journal of Medical Imaging and Radiation Oncology Pub Date : 2025-07-14 DOI: 10.1111/1754-9485.13862
{"title":"ANZSNR 2025 ASM Abstracts.","authors":"","doi":"10.1111/1754-9485.13862","DOIUrl":"https://doi.org/10.1111/1754-9485.13862","url":null,"abstract":"","PeriodicalId":16218,"journal":{"name":"Journal of Medical Imaging and Radiation Oncology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144637234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
AI Revolution in Radiology, Radiation Oncology and Nuclear Medicine: Transforming and Innovating the Radiological Sciences. 放射学、放射肿瘤学和核医学中的人工智能革命:改变和创新放射科学。
IF 2.2 4区 医学
Journal of Medical Imaging and Radiation Oncology Pub Date : 2025-07-09 DOI: 10.1111/1754-9485.13880
S Carriero, R Canella, F Cicchetti, A Angileri, A Bruno, P Biondetti, R R Colciago, A D'Antonio, G Della Pepa, F Grassi, V Granata, C Lanza, S Santicchia, A Miceli, A Piras, V Salvestrini, G Santo, F Pesapane, A Barile, G Carrafiello, A Giovagnoni
{"title":"AI Revolution in Radiology, Radiation Oncology and Nuclear Medicine: Transforming and Innovating the Radiological Sciences.","authors":"S Carriero, R Canella, F Cicchetti, A Angileri, A Bruno, P Biondetti, R R Colciago, A D'Antonio, G Della Pepa, F Grassi, V Granata, C Lanza, S Santicchia, A Miceli, A Piras, V Salvestrini, G Santo, F Pesapane, A Barile, G Carrafiello, A Giovagnoni","doi":"10.1111/1754-9485.13880","DOIUrl":"https://doi.org/10.1111/1754-9485.13880","url":null,"abstract":"<p><p>The integration of artificial intelligence (AI) into clinical practice, particularly within radiology, nuclear medicine and radiation oncology, is transforming diagnostic and therapeutic processes. AI-driven tools, especially in deep learning and machine learning, have shown remarkable potential in enhancing image recognition, analysis and decision-making. This technological advancement allows for the automation of routine tasks, improved diagnostic accuracy, and the reduction of human error, leading to more efficient workflows. Moreover, the successful implementation of AI in healthcare requires comprehensive education and training for young clinicians, with a pressing need to incorporate AI into residency programmes, ensuring that future specialists are equipped with traditional skills and a deep understanding of AI technologies and their clinical applications. This includes knowledge of software, data analysis, imaging informatics and ethical considerations surrounding AI use in medicine. By fostering interdisciplinary integration and emphasising AI education, healthcare professionals can fully harness AI's potential to improve patient outcomes and advance the field of medical imaging and therapy. This review aims to evaluate how AI influences radiology, nuclear medicine and radiation oncology, while highlighting the necessity for specialised AI training in medical education to ensure its successful clinical integration.</p>","PeriodicalId":16218,"journal":{"name":"Journal of Medical Imaging and Radiation Oncology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144591404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Imaging Clues to Differentiate Uterine From Adnexal Masses-Value of Vascular Anatomy and Enhancement Patterns-A Pictorial Essay. 鉴别子宫肿块与附件肿块的影像学线索-血管解剖和增强模式的价值-一篇图片文章。
IF 2.2 4区 医学
Journal of Medical Imaging and Radiation Oncology Pub Date : 2025-07-02 DOI: 10.1111/1754-9485.13875
Chandrika Kandur, Amit Patle, Abhishek Arora, Annapurna Srirambhatla
{"title":"Imaging Clues to Differentiate Uterine From Adnexal Masses-Value of Vascular Anatomy and Enhancement Patterns-A Pictorial Essay.","authors":"Chandrika Kandur, Amit Patle, Abhishek Arora, Annapurna Srirambhatla","doi":"10.1111/1754-9485.13875","DOIUrl":"https://doi.org/10.1111/1754-9485.13875","url":null,"abstract":"<p><p>In gynaecologic imaging, recognising the organ of origin of a pelvic mass, uterine versus adnexal, is crucial because it significantly impacts the surgical approach and treatment outcome. Ultrasound is the first line of imaging for female pelvic masses. However, due to its inherent drawbacks, ultrasonography cannot delineate the origin of large masses that distort the normal relations between the pelvic organs. Contrast-enhanced MR imaging (CE-MRI) is a problem-solving tool due to its multidimensional imaging capabilities and soft tissue contrast. Imaging features such as the anatomical location, signal intensity of mass on T2W images, displacement/mass effect on adjacent pelvic/vascular structures and enhancement patterns are studied for making this distinction. A key aspect of this differentiation is the analysis of vascular anatomy, displacement of vessels and the patterns of enhancement. This pictorial essay discusses how the vascular supply, displacement of vessels and enhancement pattern of masses on MRI provide imaging clues which help in distinguishing uterine from adnexal masses.</p>","PeriodicalId":16218,"journal":{"name":"Journal of Medical Imaging and Radiation Oncology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144540518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of PET-CT in Cancer Patients Aged 85 and Older: A Tool for Precision or Overutilisation. PET-CT在85岁及以上癌症患者中的作用:一种精确或过度使用的工具。
IF 2.2 4区 医学
Journal of Medical Imaging and Radiation Oncology Pub Date : 2025-07-02 DOI: 10.1111/1754-9485.13879
Efkan Kaya, Ozgur Tanriverdi, Sabri Barutca
{"title":"The Role of PET-CT in Cancer Patients Aged 85 and Older: A Tool for Precision or Overutilisation.","authors":"Efkan Kaya, Ozgur Tanriverdi, Sabri Barutca","doi":"10.1111/1754-9485.13879","DOIUrl":"https://doi.org/10.1111/1754-9485.13879","url":null,"abstract":"<p><strong>Introduction: </strong>This study investigates the role of positron emission tomography-computed tomography in the treatment decision-making process for cancer patients aged 85 years and older.</p><p><strong>Methods: </strong>Retrospective study including 137 patients. Patients aged ≥ 85 years with histopathological solid malignancy. Demographic characteristics and comorbidities as well as performance status (ECOG), tumour characteristics, imaging modalities and treatment choices were variables. Patients were categorised according to PET-CT use, and statistical analyses including Mann-Whitney U test, Bonferroni correction and binary logistic regression were performed to identify independent predictors of PET-CT use.</p><p><strong>Results: </strong>The majority of patients had ECOG 2 (69%), thoracic (32%) cancer and metastatic (70%) at diagnosis, with a median age of 89 years (range: 85-99). Comorbidities were common (73%), and the most common organ dysfunctions were renal (25%) and heart failure (24%). PET-CT was performed in 47% of the patients. PET-CT was predominantly used in patients with metastatic disease, those who had received radiotherapy and those who were given best supportive care. However, patients undergoing PET-CT had significantly lower rates of curative treatment (3% vs. 18%, p = 0.0016). Binary logistic regression identified best supportive care decision as the only independent predictor of PET-CT use.</p><p><strong>Conclusions: </strong>The findings indicated that PET-CT is commonly used for staging in patients who are ultimately managed with palliative care. Future research should address the cost-effectiveness of PET-CT, appropriate imaging indications, and its impact on cancer-related outcomes.</p>","PeriodicalId":16218,"journal":{"name":"Journal of Medical Imaging and Radiation Oncology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144540467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paediatric Varicocele Embolisation: Clinical Experience, Insights and Long Term Clinical Outcomes Over 14 Years at a Tertiary Centre-A Cohort Study. 儿科精索静脉曲张栓塞:临床经验,见解和长期临床结果超过14年的三级中心- a队列研究。
IF 2.2 4区 医学
Journal of Medical Imaging and Radiation Oncology Pub Date : 2025-07-02 DOI: 10.1111/1754-9485.13878
Fiona S Lau, John K Pereira, Ashish Jiwane, Priya McGregor
{"title":"Paediatric Varicocele Embolisation: Clinical Experience, Insights and Long Term Clinical Outcomes Over 14 Years at a Tertiary Centre-A Cohort Study.","authors":"Fiona S Lau, John K Pereira, Ashish Jiwane, Priya McGregor","doi":"10.1111/1754-9485.13878","DOIUrl":"https://doi.org/10.1111/1754-9485.13878","url":null,"abstract":"<p><strong>Introduction: </strong>Varicocele is a correctable cause of male infertility with management options including catheter embolisation of the testicular vein, done by Interventional Radiologists. Varicoceles can present in childhood and adolescence with scrotal pain or discomfort, or may be subclinical. It involves dilatation of the pampiniform plexus related to congestion and retrograde flow in the testicular vein. If left untreated, the pain and discomfort may impact the quality of life of the paediatric patient, and in the long term, infertility may ensue. However, limited data are available on the long-term clinical outcomes and complications of Varicocele embolisation in paediatric patients.</p><p><strong>Method: </strong>Retrospective cohort study of 14 years of endovascular Varicocele embolisation at a single-operator tertiary paediatric centre.</p><p><strong>Results: </strong>Eighty-four patients with a median age of 14 years (range 8-17 years) were identified. The varicoceles were predominantly of grade 1 or 2. 99% of patients had unilateral left-sided varicoceles. One patient had bilateral varicoceles. This study demonstrated that the technical success rate of endovascular embolisation is 94% and the clinical success rate is 98%. 84% reported feeling well in the immediate postprocedural period. 86% of cases reported excellent long-term progress. A small proportion (10%) experienced long-term discomfort or pain. There were no cases of relapse.</p><p><strong>Conclusion: </strong>Endovascular embolisation is a successful technique for the management of Varicocele in paediatric patients, with good immediate and long-term clinical outcomes. It has low recurrence rates.</p>","PeriodicalId":16218,"journal":{"name":"Journal of Medical Imaging and Radiation Oncology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144540466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use and Perceptions of Oncology CT Structured Reports in Australia and New Zealand. 澳大利亚和新西兰肿瘤CT结构化报告的使用和认知。
IF 2.2 4区 医学
Journal of Medical Imaging and Radiation Oncology Pub Date : 2025-07-02 DOI: 10.1111/1754-9485.13860
K J Brown, A Agarwal, K L Gormly
{"title":"Use and Perceptions of Oncology CT Structured Reports in Australia and New Zealand.","authors":"K J Brown, A Agarwal, K L Gormly","doi":"10.1111/1754-9485.13860","DOIUrl":"https://doi.org/10.1111/1754-9485.13860","url":null,"abstract":"<p><strong>Introduction: </strong>Structured oncology template (OT) reports are preferred by physicians. Promoted in Australia and New Zealand (ANZ) since 2008, this study investigates the current OT use in ANZ and perceptions around OT reporting.</p><p><strong>Methods: </strong>An online survey was created and sent to > 350 ANZ radiologists, aiming to gain insight into the current rates of OT reporting, demographic variations, OT types, implementation and perceived advantages and limitations. Statistical analyses were descriptive.</p><p><strong>Results: </strong>Of 164 respondents, 21% never used an OT; 49% used OTs for > 75% of oncology reports, highest rates were those with 10-20 years of experience (29/61) and reporting > 10 oncology CTs per week (10-20 cases 74% and > 20 cases 72%); 72% used tumour, lymph node and metastases headings; 57% used OTs for all diagnosed cancers; 37% used measurement tables; 70% used subjective terms in their conclusion; and only 4% used synoptic reports. Most selected advantage was 'More clarity and increased communication with clinicians'. Most selected disadvantage was 'lack of experience in template reporting' for those using an OT and 'Inflexible and limits creativity' for those who did not.</p><p><strong>Conclusion: </strong>OT use is supported across ANZ. Use is higher in those reporting more oncology cases and with 10-20 years of experience. OT reports are perceived as beneficial by those using them, while those who do not perceive them as inflexible.</p>","PeriodicalId":16218,"journal":{"name":"Journal of Medical Imaging and Radiation Oncology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144540468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FDG Extravasation in PET/CT Imaging: A Visual Grading Approach Based on Clinical Observations. PET/CT影像中FDG外渗:基于临床观察的视觉分级方法。
IF 2.2 4区 医学
Journal of Medical Imaging and Radiation Oncology Pub Date : 2025-07-02 DOI: 10.1111/1754-9485.13876
Seçkin Bilgiç
{"title":"FDG Extravasation in PET/CT Imaging: A Visual Grading Approach Based on Clinical Observations.","authors":"Seçkin Bilgiç","doi":"10.1111/1754-9485.13876","DOIUrl":"https://doi.org/10.1111/1754-9485.13876","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to introduce a practical, visually based grading system for FDG extravasation in PET/CT imaging and to investigate its impact on semi-quantitative SUV measurements in reference regions. The objective is not only to quantify the effect but also to provide a framework for guiding clinical interpretation and reporting.</p><p><strong>Methods: </strong>A total of 235 oncologic PET/CT scans were retrospectively analysed. Patients were categorised into four groups based on extravasation severity: Grade 0 (no extravasation), Grade 1 (minimal), Grade 2 (moderate), and Grade 3 (severe). A visual grading system was developed and applied to classify image quality degradation. Mean SUVmax and SUVmean values were recorded from liver and mediastinal blood pool regions. Statistical comparisons were conducted using ANOVA and post hoc testing.</p><p><strong>Results: </strong>FDG extravasation was observed in 75 patients (31.9%). Among the 75 patients with extravasation, 43 were Grade 1 and 26 were Grade 2. Statistically significant increases were found in both liver and mediastinal SUV values in patients with Grade 1 and 2 extravasation compared to Grade 0 (p < 0.001 for all). For example, Liver SUVmax increased from 3.13 ± 0.44 (Grade 0) to 3.58 ± 0.50 (Grade 1), and MedSUVmean increased from 1.80 ± 0.31 (Grade 0) to 2.17 ± 0.40 (Grade 2), representing up to a 20.6% difference. Grade 3 cases did not show consistent trends.</p><p><strong>Conclusion: </strong>Low-to-moderate FDG extravasation can significantly alter reference SUV values. Incorporating extravasation grading into clinical reporting or normalising reference SUV values may enhance diagnostic consistency and minimise the need for repeat imaging.</p>","PeriodicalId":16218,"journal":{"name":"Journal of Medical Imaging and Radiation Oncology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144540517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Commentary to: A Greener Path for Interventional Radiology. 评论:介入放射学的绿色之路。
IF 2.2 4区 医学
Journal of Medical Imaging and Radiation Oncology Pub Date : 2025-07-02 DOI: 10.1111/1754-9485.13877
Valeria Noguera, Laura Manuela Olarte Bermúdez, David Fernando Torres Cortes, Juan Andres Mejia
{"title":"Commentary to: A Greener Path for Interventional Radiology.","authors":"Valeria Noguera, Laura Manuela Olarte Bermúdez, David Fernando Torres Cortes, Juan Andres Mejia","doi":"10.1111/1754-9485.13877","DOIUrl":"https://doi.org/10.1111/1754-9485.13877","url":null,"abstract":"","PeriodicalId":16218,"journal":{"name":"Journal of Medical Imaging and Radiation Oncology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144540516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SPAN-C: Results of a Phase II Clinical Trial of Stereotactic Body Radiotherapy in Pancreatic Ductal Adenocarcinoma. SPAN-C:立体定向体放疗治疗胰腺导管腺癌的II期临床试验结果。
IF 2.2 4区 医学
Journal of Medical Imaging and Radiation Oncology Pub Date : 2025-06-16 DOI: 10.1111/1754-9485.13874
Joseph Chan, Andrew Kneebone, Gabrielle Metz, Jeremy Booth, Meegan Shepherd, Carol Kwong, Chris Brown, Ian Norton, Stephen Clarke, Connie Diakos, Nick Pavlakis, Anubhav Mittal, Jaswinder Samra, George Hruby
{"title":"SPAN-C: Results of a Phase II Clinical Trial of Stereotactic Body Radiotherapy in Pancreatic Ductal Adenocarcinoma.","authors":"Joseph Chan, Andrew Kneebone, Gabrielle Metz, Jeremy Booth, Meegan Shepherd, Carol Kwong, Chris Brown, Ian Norton, Stephen Clarke, Connie Diakos, Nick Pavlakis, Anubhav Mittal, Jaswinder Samra, George Hruby","doi":"10.1111/1754-9485.13874","DOIUrl":"https://doi.org/10.1111/1754-9485.13874","url":null,"abstract":"<p><strong>Introduction: </strong>The role of stereotactic body radiotherapy (SBRT) remains unclear in the setting of pancreatic ductal adenocarcinoma (PDAC). This study aims to investigate the safety, feasibility and benefits of SBRT for PDAC in a clinical trial setting.</p><p><strong>Methods: </strong>SPAN-C was a single centre, single-arm, phase II clinical trial. Patients with locally advanced, borderline resectable, and metastatic PDAC suitable for high dose radiation were enrolled. Fiducial marker placement was mandated. Following induction chemotherapy, patients were treated with 40-45Gy in 5 fractions of external beam radiotherapy. Freedom from local failure at 12 months was the primary endpoint. Secondary endpoints included disease recurrence endpoints, acute and late toxicity, surgical outcomes, and palliative endpoints.</p><p><strong>Results: </strong>Thirty patients were enrolled. Median follow up of alive patients was 5 years (min 31 months). Twenty-six completed treatment as per protocol. Nine patients (34.6%) underwent a resection, 5 of whom had a R0 resection and 2 had a complete pathologic response. The 12-month freedom from local failure was 100% for the resected subgroup and 76.5% for the unresected subgroup. Seven patients (26.9%) had local recurrences, with 5 of these in the unresected group (29.4%). Median OS was 37.9 months for the resected subgroup and 10.7 months for the unresected subgroup. Three patients had grade 3 acute toxicity, and no patients had late high-grade toxicity.</p><p><strong>Conclusions: </strong>SBRT was safe and feasible with high rates of local control at 12 months and low rates of toxicity. It appears a valid alternative to chemo-irradiation in both the pre-operative and inoperable setting.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov identifier: NCT03505229.</p>","PeriodicalId":16218,"journal":{"name":"Journal of Medical Imaging and Radiation Oncology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploration of Diffusion Tensor Imaging for Delineating Target Volume Boundary in Glioblastoma Radiotherapy. 胶质母细胞瘤放射治疗中弥散张量成像划定靶体积边界的探讨。
IF 2.2 4区 医学
Journal of Medical Imaging and Radiation Oncology Pub Date : 2025-06-10 DOI: 10.1111/1754-9485.13873
Lei Tian, Wenyan Wang, Wei Sun, Huandi Zhou, Zhiqing Xiao, Xuetao Han, Xing Kang, Xiaoying Xue
{"title":"Exploration of Diffusion Tensor Imaging for Delineating Target Volume Boundary in Glioblastoma Radiotherapy.","authors":"Lei Tian, Wenyan Wang, Wei Sun, Huandi Zhou, Zhiqing Xiao, Xuetao Han, Xing Kang, Xiaoying Xue","doi":"10.1111/1754-9485.13873","DOIUrl":"https://doi.org/10.1111/1754-9485.13873","url":null,"abstract":"<p><strong>Purpose: </strong>The objective of this study is to investigate the variations in diffusion tensor imaging (DTI) parameters at different distances surrounding the operative cavity, with a specific focus on exploring the potential utility of DTI in accurately delineating radiotherapy clinical target volume for glioblastoma patients.</p><p><strong>Methods: </strong>A retrospective study was conducted on 41 patients with glioblastoma, in which apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values were measured at various distances beyond the surgical cavity. Recurrent patients were prospectively followed up according to the RANO criteria, aiming to investigate discrepancies between ADC and FA values in recurrent regions compared to normal control tissues prior to recurrence.</p><p><strong>Results: </strong>The rADC and rFA ratio approach 1 at a distance of 3 cm beyond the cavity. At the edge of the operative cavity and 2 cm beyond, the subtotal resection (STR) group exhibited higher ADC and rADC values compared to the gross total resection (GTR) group (p < 0.05). Similarly, FA and rFA values in the STR group were lower than those in the total resection group both at 1 cm beyond and 2 cm beyond (p < 0.05). Conventional MRI did not reveal any abnormalities prior to marginal or distant recurrence; however, the ADC value within this region was higher than that of control normal tissues (p = 0.023).</p><p><strong>Conclusions: </strong>The margins of GBM tumour invasion are typically not isotropic and could be > 2 cm and sometimes up to 3 cm. We recommend appropriately larger expansion of the target volume for patients with subtotal tumour resection. The utilisation of DTI in delineating the boundary of GBM's radiotherapy clinical target volume represents a promising avenue that holds potential to enhance precision and accuracy.</p>","PeriodicalId":16218,"journal":{"name":"Journal of Medical Imaging and Radiation Oncology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144266435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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