Journal of Investigative Surgery最新文献_第4页

Effect of Ileal Feces Transplantation in Preventing Diversion Colitis and Its Complications Due to Protective Loop Ileostomy in Rectal Cancer Cases. 回肠粪便移植预防直肠癌保护性回肠造口术后转流性结肠炎及其并发症的效果。

IF 2.7 4区医学

Journal of Investigative Surgery Pub Date : 2026-12-01 Epub Date: 2026-01-22 DOI: 10.1080/08941939.2025.2609429

Remzi Can Cakir, Nurhan Haluk Belen, Senay Yildirim, Sema Avci, Aydin Dincer, Murat Kazim Kazan, Omer Celik, Arif Aslaner, Kemal Eyvaz, Tugrul Cakir

{"title":"Effect of Ileal Feces Transplantation in Preventing Diversion Colitis and Its Complications Due to Protective Loop Ileostomy in Rectal Cancer Cases.","authors":"Remzi Can Cakir, Nurhan Haluk Belen, Senay Yildirim, Sema Avci, Aydin Dincer, Murat Kazim Kazan, Omer Celik, Arif Aslaner, Kemal Eyvaz, Tugrul Cakir","doi":"10.1080/08941939.2025.2609429","DOIUrl":"10.1080/08941939.2025.2609429","url":null,"abstract":"To evaluate the effectiveness of fecal transplantation (FT) in preventing the development of diversion colitis (DC) and reducing its complications in patients who underwent protective loop ileostomy (PLI) following low anterior resection for rectal cancer. The study was prospectively conducted at Tertiary Hospital. Seventeen patients who underwent PLI were assigned to the FT group (FT+), and 19 patients served as the control group (FT-). In the FT+ group, ileal content was delivered to the efferent loop via a catheter placed during surgery. Both groups were evaluated postoperatively through biopsies taken for histopathological examination. In the FT+ group, significant reductions were observed in parameters specific to DC, such as the severity of inflammation, ulceration, goblet cell loss, and crypt abscesses, compared to the FT- group (p < 0.05). The epithelial structure and crypt organization in the FT+ group were closer to normal. FT is an effective and easily applicable method for preventing DC development and reducing the severity of inflammatory changes in patients undergoing PLI. The technique is low-cost, has high patient compliance, and aligns with methods reported in the literature for DC prevention.","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"39 1","pages":"2609429"},"PeriodicalIF":2.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146029907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of PA-MSHA on Postoperative Seroma Formation and Tissue Remodeling in Rat Abdominal Wall Hernia Model. PA-MSHA对大鼠腹壁疝模型术后血肿形成及组织重塑的影响。

IF 2.7 4区医学

Journal of Investigative Surgery Pub Date : 2026-12-01 Epub Date: 2026-07-22 DOI: 10.1080/08941939.2026.2706949

Wenke Guo, Bin Fei, Haigang Niu, Chuya Shi, Yaoqiang Ren, Xia Ren, Xinrui Liu

{"title":"Impact of PA-MSHA on Postoperative Seroma Formation and Tissue Remodeling in Rat Abdominal Wall Hernia Model.","authors":"Wenke Guo, Bin Fei, Haigang Niu, Chuya Shi, Yaoqiang Ren, Xia Ren, Xinrui Liu","doi":"10.1080/08941939.2026.2706949","DOIUrl":"https://doi.org/10.1080/08941939.2026.2706949","url":null,"abstract":"Background: Seroma is one of the most common postoperative complications following hernia repair. This study evaluated whether the local application of Pseudomonas aeruginosa injection (PA-MSHA) could reduce the duration of seroma and promote healing of the graft and surrounding tissues after abdominal wall incisional hernia repair.Methods: 56 Sprague-Dawley rats were used to assess the efficacy and optimal dosage of PA-MSHA in reducing seroma formation after latissimus dorsi resection. 54 rats underwent abdominal wall hernia repair and were randomly assigned to three groups: sham, saline, or PA-MSHA. Seroma formation was monitored, and tissue samples were collected for histological and immunohistochemical analyses.Results: Among five groups, the medium-dose group (0.1 mL/kg) demonstrated the most significant reduction in seroma volume. PA-MSHA significantly shortened the duration of seroma and enhanced both early and mid-term tissue healing. Sirius Red staining indicated a significantly higher collagen type I/III ratio on days 7 and 14. Immunohistochemical analysis demonstrated elevated expression of CD68 and CD31 during the early healing phase in the PA-MSHA group. By day 28, graft shrinkage did not differ significantly among the groups.Conclusions: Intraoperative local administration of PA-MSHA effectively reduced seroma persistence and enhanced early tissue regeneration and abdominal wall integrity without triggering excessive foreign body reactions or adverse events.","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"39 1","pages":"2706949"},"PeriodicalIF":2.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148562314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluating the Feasibility of Breast-Conserving Surgery in Breast Cancer Patients with Suspicious Calcifications After Neoadjuvant Chemotherapy: A Retrospective Cohort Study. 评价新辅助化疗后可疑钙化乳腺癌患者保乳手术的可行性：一项回顾性队列研究。

IF 2.7 4区医学

Journal of Investigative Surgery Pub Date : 2026-12-01 Epub Date: 2026-03-11 DOI: 10.1080/08941939.2026.2624199

Lingrui Li, Xiangyu Wang, Xiangyi Kong, Wenxiang Zhang, Zhongzhao Wang, Yi Fang, Xiaoying He, Jing Wang

{"title":"Evaluating the Feasibility of Breast-Conserving Surgery in Breast Cancer Patients with Suspicious Calcifications After Neoadjuvant Chemotherapy: A Retrospective Cohort Study.","authors":"Lingrui Li, Xiangyu Wang, Xiangyi Kong, Wenxiang Zhang, Zhongzhao Wang, Yi Fang, Xiaoying He, Jing Wang","doi":"10.1080/08941939.2026.2624199","DOIUrl":"10.1080/08941939.2026.2624199","url":null,"abstract":"Background: Suspicious calcifications in breast cancer (BC) often limit eligibility for breast-conserving surgery (BCS) after neoadjuvant chemotherapy (NAC). This study assessed the impact of ductal carcinoma in situ (DCIS) status and post-NAC imaging changes on pathological complete response (pCR), BCS feasibility, and prognosis.Methods: We retrospectively analyzed 163 BC patients with suspicious calcifications treated with NAC (median follow-up, 38.9 months). Logistic regression identified predictors of pCR, associations between calcification changes and pCR were assessed using Cramer's V, and OS and DFS were evaluated using Kaplan-Meier analysis.Results: 73 patients had DCIS and 90 had non-DCIS. Calcification reduction after NAC was more frequent in non-DCIS group (56.7%; p = 0.012). pCR rates were higher in non-DCIS group than in DCIS group (73.7% vs 26.3%; p = 0.015). After adjustment, DCIS was associated with reduced pCR rates (OR: 0.26, 95% CI: 0.08-0.73). Overall BCS rate was 11%. Calcification reduction showed a weak correlation with pCR (Cramer's V = 0.321). No significant OS, DFS, or BCS differences were observed by DCIS status or calcification change within follow-up.Conclusion: DCIS is associated with reduced pCR after NAC. Calcification findings alone should be interpreted cautiously, and BCS feasibility should be assessed using comprehensive surgical criteria.","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"39 1","pages":"2624199"},"PeriodicalIF":2.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147433386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Subretinal Fluid on Macular Microstructure and Visual Acuity After Surgery for Rhegmatogenous Retinal Detachment. 视网膜下液对孔源性视网膜脱离术后黄斑微结构及视力的影响。

IF 2.7 4区医学

Journal of Investigative Surgery Pub Date : 2026-12-01 Epub Date: 2026-01-15 DOI: 10.1080/08941939.2025.2594557

Qingyue Meng, Zixu Cheng, Yuhua Hao

{"title":"The Effect of Subretinal Fluid on Macular Microstructure and Visual Acuity After Surgery for Rhegmatogenous Retinal Detachment.","authors":"Qingyue Meng, Zixu Cheng, Yuhua Hao","doi":"10.1080/08941939.2025.2594557","DOIUrl":"10.1080/08941939.2025.2594557","url":null,"abstract":"Objective: To investigate the effect of persistent subretinal fluid (SRF) on macular microstructure and visual acuity after surgery for rhegmatogenous retinal detachment (RRD).Methods: RRD patients diagnosed between January 2020 and March 2023 who underwent successful scleral buckling (SB) surgery with SRF present 3 months post-operation were retrospectively analyzed. Patients were divided into short-term absorption (Group A, n = 40) and delayed absorption groups (Group B, n = 50). Data on best corrected visual acuity (BCVA), retinal nerve fiber layer thickness (RNFL), subfoveal choroidal thickness (SFCT), and vascular densities were collected at various time points.Results: BCVA and SFCT showed a downward trend over time, with Group A exhibiting higher values than Group B at multiple time points (P < 0.05). RNFL also decreased over time, but Group A consistently had higher measurements. The choriocapillary plexus vessel density (CCP-VD) decreased in Group B while showing fluctuations in Group A, with higher values in Group A at 3 and 6 months post-absorption (P < 0.001).Conclusion: After SB surgery, foveal RNFL increased while SFCT decreased, with the short-term absorption group displaying more significant improvements. Additionally, vessel densities decreased over time, and the delayed absorption group showed more substantial decreases in CCP-VD.","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"39 1","pages":"2594557"},"PeriodicalIF":2.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145970937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter to the Editor: Methodological Comments on "Acupoint Stimulation After Anesthesia Induction Does Not Decrease Nausea and Vomiting After Hepatectomy: A Multi-Center Double-Blinded Clinical Trial". 致编者信：关于“麻醉诱导后穴位刺激不能减少肝切除术后恶心呕吐：一项多中心双盲临床试验”的方法学评论。

IF 2.7 4区医学

Journal of Investigative Surgery Pub Date : 2026-12-01 Epub Date: 2026-05-29 DOI: 10.1080/08941939.2026.2679332

Qunmei Huang, Sangyi Lin, Cong Wang, Haifeng Zhang

引用次数: 0

Comparison of the Efficacy of Robot-Assisted and Laparoscopic Anderson-Hynes Pyeloplasty in Pediatric Patients with Ureteropelvic Junction Obstruction. 机器人辅助与腹腔镜下肾盂成形术治疗小儿肾盂输尿管连接处梗阻的疗效比较。

IF 2.7 4区医学

Journal of Investigative Surgery Pub Date : 2026-12-01 Epub Date: 2026-09-11 DOI: 10.1080/08941939.2026.2705609

Zhipeng Li, Zhengyan Wang, Huake Wang, Haidan Li, Yixuan Li, Zhuoheng Li, Guifu Zhang, Hongjin Shi, Haifeng Wang

{"title":"Comparison of the Efficacy of Robot-Assisted and Laparoscopic Anderson-Hynes Pyeloplasty in Pediatric Patients with Ureteropelvic Junction Obstruction.","authors":"Zhipeng Li, Zhengyan Wang, Huake Wang, Haidan Li, Yixuan Li, Zhuoheng Li, Guifu Zhang, Hongjin Shi, Haifeng Wang","doi":"10.1080/08941939.2026.2705609","DOIUrl":"https://doi.org/10.1080/08941939.2026.2705609","url":null,"abstract":"Background: Comparative evidence on robot-assisted laparoscopic pyeloplasty (RALP) versus laparoscopic pyeloplasty (LP) in pediatric ureteropelvic junction obstruction (UPJO), particularly regarding postoperative anatomical changes, differential renal function (DRF), and urinary tract dilation (UTD) stratification, remains limited.Methods: We retrospectively reviewed 63 children with UPJO who underwent Anderson-Hynes pyeloplasty at a tertiary center between 2018 and 2022, including 21 RALP and 42 LP cases. Patients were classified as UTD P1-P3. Perioperative outcomes, recovery, imaging findings, DRF, complications, and follow-up results were compared.Results: Median follow-up was 16 months. Both groups showed significant improvements in anteroposterior pelvic diameter (APD), renal pelvic dilation, and renal cortical thickness (all p < 0.05). Compared with LP, RALP was associated with less blood loss (p = 0.002), smaller postoperative APD (p = 0.005), and higher postoperative DRF (p = 0.002), but longer operative time (p = 0.048). Complication rates were comparable.Conclusion: Both RALP and LP provided favorable short- to mid-term outcomes in children with UPJO. RALP may offer advantages in blood loss and postoperative anatomical and functional recovery, although its longer operative time and the retrospective design warrant cautious interpretation. Larger prospective multicenter studies are needed.","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"39 1","pages":"2705609"},"PeriodicalIF":2.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148945131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy and Safety of En-Bloc Laser Enucleation of the Prostate for Benign Prostatic Obstruction: An Evidence-Based Analysis of Clinical Studies. 前列腺激光整体摘除治疗良性前列腺梗阻的有效性和安全性：临床研究的循证分析。

IF 3.5 4区医学

Journal of Investigative Surgery Pub Date : 2026-12-01 Epub Date: 2026-06-09 DOI: 10.1080/08941939.2026.2666954

Jinze Li, Jing Liu, Puze Wang, Peihai Zhang, Dong Lv

{"title":"Efficacy and Safety of En-Bloc Laser Enucleation of the Prostate for Benign Prostatic Obstruction: An Evidence-Based Analysis of Clinical Studies.","authors":"Jinze Li, Jing Liu, Puze Wang, Peihai Zhang, Dong Lv","doi":"10.1080/08941939.2026.2666954","DOIUrl":"10.1080/08941939.2026.2666954","url":null,"abstract":"Background and objective: This study compared the efficacy and safety of En-Bloc and standard techniques in laser enucleation, providing an evidence-based basis for surgical decision-making in the management of benign prostatic obstruction (BPO).Methods: Relevant studies were systematically identified through searches of PubMed, Embase, Web of Science, and Cochrane Library databases up to May 2025. Data analysis was performed using RevMan 5.4.Results: Data from 15 studies containing 9,397 participants were reviewed. The En-Bloc technique was associated with a reduction in enucleation time (mean difference [MD] - 8.43, 95% CI -13.0 to -3.91, p < 0.001), an increase in enucleation efficiency (MD 0.21, 95% CI 0.07 to 0.36, p = 0.004), a decrease in operative time (MD -4.70, 95% CI -8.81 to -0.60, p = 0.02), and a lower rate of major complications (odds ratio 0.62, 95% CI 0.42-0.90, p = 0.01) than the standard technique. No significant differences in postoperative short-term functional outcomes were found.Conclusions: The updated evidence suggests that the En-Bloc technique is associated with improved perioperative performance and a lower rate of major complications compared to the conventional approach, while preserving comparable functional outcomes. These findings suggest potential clinical benefits of En-Bloc enucleation in the surgical management of BPO.","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"39 1","pages":"2666954"},"PeriodicalIF":3.5,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148211498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patients with Favorable Prognosis among Those Selected for Liver Resection for Intermediate-Stage Hepatocellular Carcinoma. 中期肝细胞癌选择肝切除术预后良好的患者。

IF 3.5 4区医学

Journal of Investigative Surgery Pub Date : 2026-12-01 Epub Date: 2026-06-09 DOI: 10.1080/08941939.2026.2684797

Yi-Hao Yen, Chee-Chien Yong, Wei-Feng Li, Yueh-Wei Liu, Chih-Chi Wang

{"title":"Patients with Favorable Prognosis among Those Selected for Liver Resection for Intermediate-Stage Hepatocellular Carcinoma.","authors":"Yi-Hao Yen, Chee-Chien Yong, Wei-Feng Li, Yueh-Wei Liu, Chih-Chi Wang","doi":"10.1080/08941939.2026.2684797","DOIUrl":"10.1080/08941939.2026.2684797","url":null,"abstract":"Background: Many studies have reported preoperative predictors of overall survival (OS) of patients undergoing liver resection (LR) for Barcelona Clinic Liver Cancer (BCLC) stage B hepatocellular carcinoma (HCC); however, their results are inconsistent.Methods: We included 170 patients with BCLC stage B undergoing LR during 2011-2021.Results: Multivariate analysis showed that alpha-fetoprotein (AFP) >50 ng/ml (hazard ratio [HR] = 1.959; 95% confidence interval [CI] = 1.156-3.319; p = 0.012), undergoing major resection (HR = 2.514; 95% CI = 1.225-5.161; p = 0.012), and indocyanine green retention rate at 15 min ≥10% (HR = 1.777; 95% CI = 1.038-3.040; p = 0.036) were associated with overall mortality. We constructed a predictive model with these variables. The model provided three risk strata for 5-year OS, low risk, medium risk, and high risk, with 5-year OS of 58%, 30%, and 12%, respectively (p < 0.001). The c-index of this model was 64.7%. The calibration plots showed overall high agreement between model predictions and observed outcomes.Conclusions: The risk prediction model we developed to predict the OS of patients undergoing LR for BCLC stage B HCC is helpful for treatment decision-making.","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"39 1","pages":"2684797"},"PeriodicalIF":3.5,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148204967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Moxibustion at the Dazhui Point on Hypothermia and Maternal Comfort During Cesarean Delivery: A Randomized Controlled Trial. 艾灸大椎穴对剖宫产产妇低温及舒适度的影响：一项随机对照试验。

IF 2.7 4区医学

Journal of Investigative Surgery Pub Date : 2026-12-01 Epub Date: 2026-06-23 DOI: 10.1080/08941939.2026.2689200

Hao Gao, Chunlan Hu, Xi Chen, Lili Li, Xiaohui Wu, Haoliang Cai, Hai Zhu, Wenting Chen, Jiangang Song

{"title":"The Effect of Moxibustion at the Dazhui Point on Hypothermia and Maternal Comfort During Cesarean Delivery: A Randomized Controlled Trial.","authors":"Hao Gao, Chunlan Hu, Xi Chen, Lili Li, Xiaohui Wu, Haoliang Cai, Hai Zhu, Wenting Chen, Jiangang Song","doi":"10.1080/08941939.2026.2689200","DOIUrl":"10.1080/08941939.2026.2689200","url":null,"abstract":"Objective: This study evaluated whether moxibustion at the Dazhui point (GV14) reduces intraoperative hypothermia during cesarean delivery under spinal anesthesia.Methods: Sixty - four parturients (32/group) scheduled for cesarean section were randomly assigned 30 min before surgery to receive either moxibustion at Dazhui or sham moxibustion (pre-combusted cooled moxa pack); both groups received standard blanket warming. The primary outcome was hypothermia incidence (core temperature <36.0 °C). Secondary outcomes included shivering, thermal comfort (0-100 scale), Apgar scores, hospital stay, and postoperative complications (fever, blood loss, infection).Results: Baseline characteristics were similar between groups. Hypothermia incidence was significantly lower in the intervention group (62.50%) than in the sham group (84.38%; p = 0.048). From 10 min after surgery start until operating room departure, core temperature remained consistently higher in the moxibustion group (p < 0.05). Shivering occurred less often in the intervention group (43.75% vs. 68.75%, p < 0.05). Thermal comfort scores were higher in the intervention group (87.19 ± 9.24 vs. 78.75 ± 10.08, p < 0.05). No significant differences were found in Apgar scores, hospital stay, or postoperative complications.Conclusion: Preoperative moxibustion at Dazhui reduces intraoperative hypothermia and improves maternal comfort during cesarean delivery without adverse neonatal effects. Although it cannot completely eliminate hypothermia or shivering, it may serve as an effective non - pharmacological adjunct for thermoregulation in obstetric anesthesia.","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"39 1","pages":"2689200"},"PeriodicalIF":2.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148301391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An International Prospective, Non-Randomized Comparative Study with Articulating Laparoscopic Instruments in Benign Adnexal Gynecologic Surgery. 一项国际前瞻性、非随机对照研究：关节式腹腔镜器械在妇科良性附件手术中的应用。

IF 2.7 4区医学

Journal of Investigative Surgery Pub Date : 2026-12-01 Epub Date: 2026-02-02 DOI: 10.1080/08941939.2026.2620177

Young Eun Chung, Seongyun Lim, Jun-Hyeong Seo, Kazuyoshi Kato, Yen-Ling Lai, Yu-Li Chen, Chel-Hun Choi, Yoo-Young Lee

{"title":"An International Prospective, Non-Randomized Comparative Study with Articulating Laparoscopic Instruments in Benign Adnexal Gynecologic Surgery.","authors":"Young Eun Chung, Seongyun Lim, Jun-Hyeong Seo, Kazuyoshi Kato, Yen-Ling Lai, Yu-Li Chen, Chel-Hun Choi, Yoo-Young Lee","doi":"10.1080/08941939.2026.2620177","DOIUrl":"10.1080/08941939.2026.2620177","url":null,"abstract":"Articulated laparoscopic instruments such as Artisential® offer enhanced dexterity compared with conventional tools, but evidence for their use in benign gynecologic surgery remains limited. This multicenter, prospective, non-randomized comparative study evaluated the feasibility and perioperative safety of Artisential® instruments using contemporaneous controls. Consecutive patients undergoing laparoscopic surgery for benign adnexal disease between December 2022 and August 2024 were enrolled in Korea, Taiwan, and Japan. Patients who consented underwent surgery using Artisential®, while those who declined were treated with conventional laparoscopic instruments and included as retrospectively collected controls. Propensity score matching was performed based on age, body mass index, history of previous abdominal surgery, and type of surgery. Outcomes included operation time, estimated blood loss, postoperative hospital stay, and Clavien-Dindo-graded complications. A total of 184 patients were analyzed, and 112 matched patients were included after matching. No significant differences were observed between groups in operative outcomes. No conversions or transfusions occurred, and postoperative complications were infrequent and limited to grade I superficial port-site issues. These findings support the feasibility and short-term safety of Artisential® instruments in benign adnexal surgery, although randomized trials are needed to further evaluate ergonomic and economic benefits.","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"39 1","pages":"2620177"},"PeriodicalIF":2.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146100218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0