引导组织再生联合微螺钉种植体支抗技术治疗牙周炎错牙合的临床疗效分析。

IF 2.1 4区 医学 Q2 SURGERY
Journal of Investigative Surgery Pub Date : 2025-12-01 Epub Date: 2025-06-09 DOI:10.1080/08941939.2025.2507233
Yi Liang, Jiajing Zou, Xianmin Meng
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引用次数: 0

摘要

目的:探讨引导组织再生(GTR)联合微螺钉种植体支抗技术治疗牙周炎合并错牙合的疗效。方法:将60例牙周炎伴错牙合患者随机分为对照组(30例,采用GTR联合传统正畸治疗)和观察组(30例,采用GTR联合微螺钉种植体支抗技术)。牙周指标[牙龈指数(GI)、龈沟出血指数(SBI)、菌斑指数(PLI)、探诊深度(PD)、临床附着水平(CAL)]、咀嚼功能(咬力、咀嚼效率)、口腔美学[粉色美学评分(PES)]、白细胞介素-6 (IL-6)、基质金属蛋白酶-8 (MMP-8)、测量两组龈沟液(龈沟液采集于三个非相邻牙周炎部位)中转化生长因子-β (TGF-β)水平。并比较两组的疗效及并发症。结果:治疗6个月后,观察组患者的GI、SBI、PLI、PD、CAL值均低于对照组,咀嚼力、咀嚼效率、PES均显著提高(p p p)。结论:GTR联合微螺钉种植体支抗治疗牙周炎、错牙合患者疗效显著。该方法可有效改善牙周健康,优化局部牙周微环境,增强咀嚼功能,促进牙齿美观。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical Efficacy Analysis of Guided Tissue Regeneration Combined with Microscrew Implant Anchorage Technique in the Treatment of Periodontitis with Malocclusion.

Objective: We aimed to explore the efficacy of guided tissue regeneration (GTR) combined with microscrew implant anchorage technique in treating patients with periodontitis and malocclusion.

Methods: Sixty patients with periodontitis accompanied by malocclusion were randomly assigned to either the control group (n = 30, receiving GTR combined with traditional orthodontic treatment) or the observation group (n = 30, receiving GTR combined with microscrew implant anchorage technique). Periodontal indicators [gingival index (GI), sulcus bleeding index (SBI), plaque index (PLI), probing depth (PD), and clinical attachment level (CAL)], chewing function (biting force, chewing efficiency), dental esthetics [pink esthetic score (PES)], as well as interleukin-6 (IL-6), matrix metalloproteinase-8 (MMP-8), and transforming growth factor-β (TGF-β) levels in gingival crevicular fluid (the gingival crevicular fluid was collected from three non-adjacent periodontitis sites) were measured in both groups. The efficacy and complications were also compared.

Results: Six months after treatment, the observation group exhibited lower GI, SBI, PLI, PD, and CAL values, and improved bit force, chewing efficiency, and PES than the control group (p < .05). Six weeks after treatment, the observation group showed reduced IL-6 and MMP-8 levels in gingival crevicular fluid and increased TGF-β levels than the control group (p < .05). Additionally, the observation group exhibited higher overall treatment efficacy than the control group (p < .05).

Conclusion: GTR combined with microscrew implant anchorage yields superior therapeutic outcomes in patients with periodontitis and malocclusion. This approach effectively improves periodontal health, optimizes the local periodontal microenvironment, enhances masticatory function, and promotes dental esthetic outcomes.

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来源期刊
CiteScore
4.20
自引率
0.00%
发文量
114
审稿时长
6-12 weeks
期刊介绍: Journal of Investigative Surgery publishes peer-reviewed scientific articles for the advancement of surgery, to the ultimate benefit of patient care and rehabilitation. It is the only journal that encompasses the individual and collaborative efforts of scientists in human and veterinary medicine, dentistry, basic and applied sciences, engineering, and law and ethics. The journal is dedicated to the publication of outstanding articles of interest to the surgical research community.
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