Journal of Investigative Surgery最新文献

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Developing an Animal Model for Swenson Transanal Endorectal Pull-Through: A New Possibility for Training and Research Purposes. 开发 Swenson 经肛门直肠内拉穿动物模型:为培训和研究提供新的可能性。
IF 2.1 4区 医学
Journal of Investigative Surgery Pub Date : 2024-12-01 Epub Date: 2024-07-14 DOI: 10.1080/08941939.2024.2376548
Maria Luiza Gandra de Meira, Renata Buraschi Antunes, Vitoria de Oliveira Zani, Gustavo Dutra de Oliveira, Diego Generoso, Erika Veruska Paiva Ortolan, Pedro Luiz Toledo de Arruda Lourenção
{"title":"Developing an Animal Model for Swenson Transanal Endorectal Pull-Through: A New Possibility for Training and Research Purposes.","authors":"Maria Luiza Gandra de Meira, Renata Buraschi Antunes, Vitoria de Oliveira Zani, Gustavo Dutra de Oliveira, Diego Generoso, Erika Veruska Paiva Ortolan, Pedro Luiz Toledo de Arruda Lourenção","doi":"10.1080/08941939.2024.2376548","DOIUrl":"https://doi.org/10.1080/08941939.2024.2376548","url":null,"abstract":"<p><p>As far as we know, no report uses the Swenson transanal endorectal pull-through technique in an animal model. Our objective is to describe the use of this technique as an experimental model for training and research purposes. Ten Norfolk hybrid rabbits were randomly selected from our experimental laboratory, with a mean weight of 3539.3 (± 678.4) g. Neither colon preparation nor fast were used before the procedures. The surgical technique was based on the description performed by Levitt et al. (2013, <i>J Pediatr Surg</i>. 2013;48(11):2289-2295). Information related to the surgical procedures and the clinical evolution in the postoperative period were recorded and analyzed. There were no deaths or severe complications. The anesthetic and the surgical times were significantly higher for the first three animals of the experiment. Our animal model proved adequate to perform the transanal endorectal Swenson pull-through technique, allowing the training of surgical skills through a model similar to the human, with few anesthetic complications and good postoperative evolution, including postoperative follow-up. We believe that it will serve as a learning tool in many institutions that are continuously searching for improved new techniques and will support new researches in this area.</p>","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141616667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation Between Basal Metabolic Rate and Clinical Outcomes in Gastric Cancer Patients: A Retrospective Study. 胃癌患者基础代谢率与临床预后的相关性:一项回顾性研究
IF 1.9 4区 医学
Journal of Investigative Surgery Pub Date : 2024-12-01 Epub Date: 2024-05-09 DOI: 10.1080/08941939.2024.2350358
Yun-Shi Huang, Xiu-Ya Zeng, Wei-Sheng Chen, Wen-Tao Cai
{"title":"Correlation Between Basal Metabolic Rate and Clinical Outcomes in Gastric Cancer Patients: A Retrospective Study.","authors":"Yun-Shi Huang, Xiu-Ya Zeng, Wei-Sheng Chen, Wen-Tao Cai","doi":"10.1080/08941939.2024.2350358","DOIUrl":"https://doi.org/10.1080/08941939.2024.2350358","url":null,"abstract":"<p><strong>Objectives: </strong>Hypermetabolism is associated with clinical prognosis of cancer patients. The aim of this study was to explore the association between basal metabolic rate (BMR) and postoperative clinical outcomes in gastric cancer patients.</p><p><strong>Methods: </strong>We collected data of 958 gastric cancer patients admitted at our center from June 2014 to December 2018. The optimal cutoff value of BMR (BMR ≤1149 kcal/day) was obtained using the X-tile plot. Logistic and Cox regression analyses were then performed to evaluate the relevant influencing factors of clinical outcomes. Finally, R software was utilized to construct the nomogram.</p><p><strong>Results: </strong>A total of 213 patients were defined as having a lower basal metabolic rate (LBMR). Univariate and multivariate analyses showed that gastric cancer patients with LBMR were more prone to postoperative complications and had poor long-term overall survival (OS). The established nomogram had good predictive power to assess the risk of OS in gastric cancer patients after radical gastrectomy (c-index was 0.764).</p><p><strong>Conclusions: </strong>Overall, LBMR on admission is associated with the occurrence of postoperative complications in gastric cancer patients, and this population has a poorer long-term survival. Therefore, there should be more focus on the perioperative management of patients with this risk factor before surgery.</p>","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140898083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laparoscopic Surgery for Superior Mesenteric Artery Syndrome. 腹腔镜手术治疗肠系膜上动脉综合征。
IF 2.1 4区 医学
Journal of Investigative Surgery Pub Date : 2024-12-01 Epub Date: 2024-08-27 DOI: 10.1080/08941939.2024.2387524
Shao-Bei Lu, Yong-Qiang Guo, Ren-Yin Chen, Yu-Feng Zhang
{"title":"Laparoscopic Surgery for Superior Mesenteric Artery Syndrome.","authors":"Shao-Bei Lu, Yong-Qiang Guo, Ren-Yin Chen, Yu-Feng Zhang","doi":"10.1080/08941939.2024.2387524","DOIUrl":"https://doi.org/10.1080/08941939.2024.2387524","url":null,"abstract":"<p><strong>Background: </strong>Superior mesenteric artery syndrome (SMAS) is a rare condition, for which laparoscopic surgery was successfully performed safely and with long-term efficacy.</p><p><strong>Methods: </strong>This single center retrospective clinical study comprised 66 patients with SMAS, surgically treated between January 2010 and January 2020, who were allocated to three different surgical groups according to their medical history and symptoms (Laparoscopic duodenojejunostomy, <i>n</i> = 35; Gastrojejunostomy, <i>n</i> = 16; Duodenojejunostomy plus gastrojejunostomy, <i>n</i> = 15). Patient demographics, surgical data and postoperative outcomes were retrieved from the medical records.</p><p><strong>Results: </strong>All operations were successfully completed laparoscopically, and with a median follow-up of 65 months, the overall symptom score was significantly reduced from 32 to 8 (<i>p</i> < 0.0001) and the BMI was increased from 17.2 kg/m<sup>2</sup> to 21.8 kg/m<sup>2</sup> (<i>p</i> < 0.0001).</p><p><strong>Conclusions: </strong>When conservative measures failed in the treatment of SMAS, laparoscopic surgery proved to be a safe and effective method. The specific surgical technique was selected according to the history and symptoms of each individual patient. To our knowledge, this study represents the largest number of laparoscopic procedures at a single center for the treatment of superior mesenteric artery syndrome.</p>","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142080540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship Between Changes in the Expression Levels of miR-134 and E2F6 in Mediating Control of Apoptosis in NMDA-Induced Glaucomatous Mice. miR-134 和 E2F6 表达水平的变化与介导 NMDA 诱导的青光眼小鼠凋亡控制之间的关系
IF 2.1 4区 医学
Journal of Investigative Surgery Pub Date : 2024-12-01 Epub Date: 2024-08-20 DOI: 10.1080/08941939.2024.2389379
Yunli Niu, Houshuo Li, Wenting Han, Ao Rong
{"title":"Relationship Between Changes in the Expression Levels of miR-134 and E2F6 in Mediating Control of Apoptosis in NMDA-Induced Glaucomatous Mice.","authors":"Yunli Niu, Houshuo Li, Wenting Han, Ao Rong","doi":"10.1080/08941939.2024.2389379","DOIUrl":"10.1080/08941939.2024.2389379","url":null,"abstract":"<p><strong>Objective: </strong>This investigation was to determine the relationship between changes in the expression levels of miR-134 and the E2F transcription factor 6 (E2F6) in mediating control of apoptosis in N-methyl-D-aspartate (NMDA)-induced glaucomatous mice.</p><p><strong>Methods: </strong>Morphological and structural changes were quantitatively analyzed along with apoptosis in the retinal ganglion cell (RGC) layer, internal plexiform layer and RGCs. Glaucomatous RGCs were transfected, and cell viability and apoptosis were examined. The targeting relationship between miR-134 and E2F6 was analyzed, as well as their expression pattern.</p><p><strong>Results: </strong>Intravitreal injection of NMDA induced a significant reduction in the number of RGCs and thinning of IPL thickness. miR-134 was highly expressed and E2F6 was lowly expressed in glaucoma mice. Suppression of miR-134 or E2F6 overexpression inhibited apoptosis in the glaucomatous RGCs and instead their proliferative activity. MiR-134 targeted inhibition of E2F6 expression. Suppressing rises in E2F6 expression reduced the interfering effect of miR-134 on glaucomatous RGC development.</p><p><strong>Conclusion: </strong>Depleting miR134 expression increases, in turn, E2F6 expression levels and in turn reduces glaucomatous RGC apoptosis expression.</p>","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142008934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Posttranscriptional Regulation of Intestinal Mucosal Growth and Adaptation by Noncoding RNAs in Critical Surgical Disorders. 重症外科疾病中非编码 RNA 对肠道黏膜生长和适应的转录后调控。
IF 1.9 4区 医学
Journal of Investigative Surgery Pub Date : 2024-12-01 Epub Date: 2024-02-07 DOI: 10.1080/08941939.2024.2308809
Cassandra A Cairns, Lan Xiao, Jian-Ying Wang
{"title":"Posttranscriptional Regulation of Intestinal Mucosal Growth and Adaptation by Noncoding RNAs in Critical Surgical Disorders.","authors":"Cassandra A Cairns, Lan Xiao, Jian-Ying Wang","doi":"10.1080/08941939.2024.2308809","DOIUrl":"10.1080/08941939.2024.2308809","url":null,"abstract":"<p><p>The human intestinal epithelium has an impressive ability to respond to insults and its homeostasis is maintained by well-regulated mechanisms under various pathophysiological conditions. Nonetheless, acute injury and inhibited regeneration of the intestinal epithelium occur commonly in critically ill surgical patients, leading to the translocation of luminal toxic substances and bacteria to the bloodstream. Effective therapies for the preservation of intestinal epithelial integrity and for the prevention of mucosal hemorrhage and gut barrier dysfunction are limited, primarily because of a poor understanding of the mechanisms underlying mucosal disruption. Noncoding RNAs (ncRNAs), which include microRNAs (miRNAs), long ncRNAs (lncRNAs), circular RNAs (circRNAs), and small vault RNAs (vtRNAs), modulate a wide array of biological functions and have been identified as orchestrators of intestinal epithelial homeostasis. Here, we feature the roles of many important ncRNAs in controlling intestinal mucosal growth, barrier function, and repair after injury-particularly in the context of postoperative recovery from bowel surgery. We review recent literature surrounding the relationships between lncRNAs, microRNAs, and RNA-binding proteins and how their interactions impact cell survival, proliferation, migration, and cell-to-cell interactions in the intestinal epithelium. With advancing knowledge of ncRNA biology and growing recognition of the importance of ncRNAs in maintaining the intestinal epithelial integrity, ncRNAs provide novel therapeutic targets for treatments to preserve the gut epithelium in individuals suffering from critical surgical disorders.</p>","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11027105/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139697587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of Problem-Based Learning Combined with Micro-Video Teaching in Burn Surgery and Its Impact on Satisfaction with Teaching. 问题式学习与微视频教学在烧伤外科中的应用及其对教学满意度的影响。
IF 2.1 4区 医学
Journal of Investigative Surgery Pub Date : 2024-12-01 Epub Date: 2024-09-26 DOI: 10.1080/08941939.2024.2403534
Zunjiang Zhao, Dalun Lv, Lei Chen
{"title":"Application of Problem-Based Learning Combined with Micro-Video Teaching in Burn Surgery and Its Impact on Satisfaction with Teaching.","authors":"Zunjiang Zhao, Dalun Lv, Lei Chen","doi":"10.1080/08941939.2024.2403534","DOIUrl":"https://doi.org/10.1080/08941939.2024.2403534","url":null,"abstract":"<p><strong>Objective: </strong>This article aimed to ascertain the application of problem-based learning (PBL) combined with micro-video teaching in burn surgery teaching and its impact on satisfaction with teaching.</p><p><strong>Methods: </strong>Fifty clinical medical students who were interns at our hospital from November 2022 to October 2023 were selected as the study subjects and randomly separated into the control group (<i>n</i> = 25) and the observation group (<i>n</i> = 25). The control group adopted traditional teaching methods. The observation group employed PBL combined with micro-video teaching mode. The scores of theory tests and skill tests, the critical thinking capability, the students' evaluation of teaching methods, the scores of teachers for teaching methods, and the scores of interns for teaching satisfaction were compared.</p><p><strong>Results: </strong>The observation group possessed higher scores on theory tests and skill tests, greater critical thinking ability after teaching, higher evaluation of teaching methods and more satisfaction with their internships versus the control group (all <i>p</i> < 0.05).</p><p><strong>Conclusion: </strong>The application of PBL combined with micro-video teaching in the teaching of burn surgery can improve students' thinking ability and their satisfaction with teaching.</p>","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142348325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reversal Surgery for Split Stoma with Peristomal Incision is Associated with Improved Postoperative Outcome in Patients with Crohn's Disease. 利用肛周切口逆转分隔造口手术可改善克罗恩病患者的术后效果。
IF 1.9 4区 医学
Journal of Investigative Surgery Pub Date : 2024-12-01 Epub Date: 2024-06-11 DOI: 10.1080/08941939.2024.2363179
Shixian Wang, Kangling Du, Ming Duan, Yihan Xu, Zhen Guo, Jianfeng Gong, Weiming Zhu, Yi Li
{"title":"Reversal Surgery for Split Stoma with Peristomal Incision is Associated with Improved Postoperative Outcome in Patients with Crohn's Disease.","authors":"Shixian Wang, Kangling Du, Ming Duan, Yihan Xu, Zhen Guo, Jianfeng Gong, Weiming Zhu, Yi Li","doi":"10.1080/08941939.2024.2363179","DOIUrl":"https://doi.org/10.1080/08941939.2024.2363179","url":null,"abstract":"<p><strong>Background: </strong>Temporary stoma formation is common in Crohn's disease (CD), while stoma reversal is associated with postoperative morbidity. This study aimed to evaluate the postoperative outcomes of split stoma reversal, SSR (i.e., exteriorization of proximal and distal ends of the stoma through a small common opening) and end stoma closure, ESC (i.e., the proximal stump externalized, and distal end localized abdominally.</p><p><strong>Methods: </strong>Patients with CD who underwent stoma reversal surgeries between January 2017 and December 2021 were included. Demographic, clinical, and postoperative data were collected and analyzed to evaluate outcomes of reversal surgery.</p><p><strong>Results: </strong>A total of 255 patients who underwent stoma reversal surgeries met the inclusion criteria. SSR was superior to ESC in terms of operative time (80.0 vs. 120.0, <i>p =</i> 0.0004), intraoperative blood loss volume (20.0 vs. 100.0, <i>p =</i> 0.0002), incision length (3.0 vs. 15.0, <i>p</i> < 0.0001), surgical wound classification (0 vs. 8.3%, <i>p</i> = 0.04), postoperative hospital stay (7.0 vs. 9.0, <i>p =</i> 0.0007), hospital expense (45.6 vs. 54.2, <i>p =</i> 0.0003), and postoperative complications (23.8% vs. 44.3%, <i>p</i> = 0.0040). Although patients in the ESC group experienced more surgical recurrence than those in the SSR group (8.3% vs. 3.2%) during the follow-up, the Kaplan-Meier curve analysis revealed no statistical difference (<i>p</i> = 0.29).</p><p><strong>Conclusions: </strong>The split stoma can be recommended when stoma construction is indicated in patients with Crohn's disease.</p>","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141306143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predicting the Risk of Postoperative Delirium in Elderly Patients Undergoing Hip Arthroplasty: Development and Assessment of a Novel Nomogram. 预测接受髋关节置换术的老年患者术后谵妄的风险:新型提名图的开发与评估
IF 2.1 4区 医学
Journal of Investigative Surgery Pub Date : 2024-12-01 Epub Date: 2024-07-22 DOI: 10.1080/08941939.2024.2381733
Yang Zhang, Li-Juan Xie, Ruo-Jie Wu, Cong-Li Zhang, Qin Zhuang, Wen-Tao Dai, Min-Xin Zhou, Xiao-Hong Li
{"title":"Predicting the Risk of Postoperative Delirium in Elderly Patients Undergoing Hip Arthroplasty: Development and Assessment of a Novel Nomogram.","authors":"Yang Zhang, Li-Juan Xie, Ruo-Jie Wu, Cong-Li Zhang, Qin Zhuang, Wen-Tao Dai, Min-Xin Zhou, Xiao-Hong Li","doi":"10.1080/08941939.2024.2381733","DOIUrl":"https://doi.org/10.1080/08941939.2024.2381733","url":null,"abstract":"<p><strong>Objective: </strong>To construct and internally validate a nomogram that predicts the likelihood of postoperative delirium in a cohort of elderly individuals undergoing hip arthroplasty.</p><p><strong>Methods: </strong>Data for a total of 681 elderly patients underwent hip arthroplasty were retrospectively collected and divided into a model (<i>n</i> = 477) and a validation cohort (<i>n</i> = 204) according to the principle of 7:3 distribution temporally. The assessment of postoperative cognitive function was conducted through the utilization of The Confusion Assessment Method (CAM). The nomogram model for postoperative cognitive impairments was established by a combination of Lasso regression and logistic regression. The receiver operating characteristic (ROC) curve, calibration plot, and decision curve analysis (DCA) were used to evaluate the performance.</p><p><strong>Results: </strong>The nomogram utilized various predictors, including age, body mass index (BMI), education, preoperative Barthel Index, preoperative hemoglobin level, history of diabetes, and history of cerebrovascular disease, to forecast the likelihood of postoperative delirium in patients. The area under the ROC curves (AUC) for the nomogram, incorporating the aforementioned predictors, was 0.836 (95% CI: 0.797-0.875) for the training set and 0.817 (95% CI: 0.755-0.880) for the validation set. The calibration curves for both sets indicated a good agreement between the nomogram's predictions and the actual probabilities.</p><p><strong>Conclusion: </strong>The use of this novel nomogram can help clinicians predict the likelihood of delirium after hip arthroplasty in elderly patients and help prevent and manage it in advance.</p>","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141748429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitative Analysis of the Causes of Falls in Adult Hospitalized Patients Based on the Perspective of Text Mining. 基于文本挖掘视角的成人住院患者跌倒原因定量分析。
IF 2.1 4区 医学
Journal of Investigative Surgery Pub Date : 2024-12-01 Epub Date: 2024-09-08 DOI: 10.1080/08941939.2024.2397578
Ying Zhang, Guichun Zhao, Zhi Zhao, Jing Luo, Ping Feng, Yahui Tong, Jianfang Zhang, Liping Tan, Wenjie Sui
{"title":"Quantitative Analysis of the Causes of Falls in Adult Hospitalized Patients Based on the Perspective of Text Mining.","authors":"Ying Zhang, Guichun Zhao, Zhi Zhao, Jing Luo, Ping Feng, Yahui Tong, Jianfang Zhang, Liping Tan, Wenjie Sui","doi":"10.1080/08941939.2024.2397578","DOIUrl":"https://doi.org/10.1080/08941939.2024.2397578","url":null,"abstract":"<p><strong>Objective: </strong>This study harnesses the power of text mining to quantitatively investigate the causative factors of falls in adult inpatients, offering valuable references and guidance for fall prevention measures within hospitals.</p><p><strong>Methods: </strong>Employing KH Coder 3.0, a cutting-edge text mining software, we performed co-occurrence network analysis and text clustering on fall incident reports of 2,772 adult patients from a nursing quality control platform in a particular city in Jiangsu Province, spanning January 2017 to December 2022.</p><p><strong>Results: </strong>Among the 2,772 patients who fell, 80.23% were aged above 60, and 73.27% exhibited physical frailty. Text clustering yielded 16 distinct categories, with four clusters implicating patient factors, four linking falls to toileting processes, four highlighting dynamic interplays between patients, the environment, and objects, and another four clusters revealing the influence of patient-caregiver interactions in causing falls.</p><p><strong>Conclusion: </strong>This study highlights the complex, multifactorial nature of falls in adult inpatients. Effective prevention requires a collaborative effort among healthcare staff, patients, and caregivers, focusing on patient vulnerabilities, environmental factors, and improved care coordination. By strengthening these aspects, hospitals can significantly reduce fall risks and promote patient safety.</p>","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142154284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Statement of Retraction: Liver X Receptors Activation Attenuates Ischemia Reperfusion Injury of Liver Graft in Rats. 撤回声明:肝X受体激活可减轻大鼠肝移植的缺血再灌注损伤
IF 1.9 4区 医学
Journal of Investigative Surgery Pub Date : 2024-12-01 Epub Date: 2024-02-12 DOI: 10.1080/08941939.2024.2308036
{"title":"Statement of Retraction: Liver X Receptors Activation Attenuates Ischemia Reperfusion Injury of Liver Graft in Rats.","authors":"","doi":"10.1080/08941939.2024.2308036","DOIUrl":"https://doi.org/10.1080/08941939.2024.2308036","url":null,"abstract":"","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139722981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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