Journal of Investigative Surgery最新文献_第2页

Application of the Branch-First Technique in Mesenteric Malperfusion Syndrome Prior to Delayed Open Aortic Repair for Acute Type A Aortic Dissection. 分支优先技术在急性A型主动脉夹层延迟开放修复前肠系膜灌注不良综合征中的应用。

IF 2.7 4区医学

Journal of Investigative Surgery Pub Date : 2026-12-01 Epub Date: 2026-02-09 DOI: 10.1080/08941939.2026.2622166

Mengmeng Ye, He Sun, Cheng Zeng, Yi Si, Weiguang Wang, Bo Yu, Hongliang Zhao, Kai Ren, Jian Xu, Bo Xu, Shiqiang Yu, Jincheng Liu, Chao Xue, Weixun Duan

{"title":"Application of the Branch-First Technique in Mesenteric Malperfusion Syndrome Prior to Delayed Open Aortic Repair for Acute Type A Aortic Dissection.","authors":"Mengmeng Ye, He Sun, Cheng Zeng, Yi Si, Weiguang Wang, Bo Yu, Hongliang Zhao, Kai Ren, Jian Xu, Bo Xu, Shiqiang Yu, Jincheng Liu, Chao Xue, Weixun Duan","doi":"10.1080/08941939.2026.2622166","DOIUrl":"10.1080/08941939.2026.2622166","url":null,"abstract":"Objective: This study evaluated delayed open aortic repair (OAR) following interventional radiology (IR) in patients with acute type A aortic dissection (ATAAD) and mesenteric malperfusion syndrome (MeMPS), and identified clinical predictors of intestinal ischemia-related organ failure.Methods: A retrospective analysis was conducted on 693 ATAAD patients (2018-2022). Thirty-seven hemodynamically stable MeMPS patients underwent upfront IR followed by delayed OAR. Controls were 656 ATAAD patients without malperfusion (Non-MPS) in any organ.Results: The overall in-hospital mortality for MeMPS patients was 43.2% (16/37). 64.9% (24/37) of MeMPS patients survived initial IR and successfully underwent delayed OAR, achieving in-hospital mortality (12.5% vs. 8.2%, p = 0.714) and short-term survival comparable to those of Non-MPS patients. 35.1% (13/37) failed to undergo OAR following IR, primarily due to refractory organ failure (n = 10) or aortic rupture (n = 3). Reduced true lumen at diaphragm (Area Under Curve, AUC = 0.717), elevated fibrin degradation product (FDP) (AUC = 0.838), and D-dimer (AUC = 0.792) performed well in predicting intestinal ischemia-related organ failure.Conclusions: For high-risk MeMPS patients, salvage IR effectively bridges to central repair with comparable in-hospital mortality and short-term survival to Non-MPS patients. The reduced true lumen at diaphragm, increased D-dimer and FDP are first identified as independent predictors of organ failure.","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"39 1","pages":"2622166"},"PeriodicalIF":2.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146142719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk Factors for Postoperative Complications After Splenectomy in Wilson's Disease: A 986-Patient Single-Center Cohort Study. 肝豆状核变性脾切除术后并发症的危险因素：一项986例患者的单中心队列研究

IF 2.7 4区医学

Journal of Investigative Surgery Pub Date : 2026-12-01 Epub Date: 2026-02-09 DOI: 10.1080/08941939.2026.2624150

Xiuquan Shi, Sihuan Zhu, Hui Peng, Lei Jin, Qingsheng Yu

{"title":"Risk Factors for Postoperative Complications After Splenectomy in Wilson's Disease: A 986-Patient Single-Center Cohort Study.","authors":"Xiuquan Shi, Sihuan Zhu, Hui Peng, Lei Jin, Qingsheng Yu","doi":"10.1080/08941939.2026.2624150","DOIUrl":"10.1080/08941939.2026.2624150","url":null,"abstract":"Introduction: Splenectomy is commonly performed in Wilson's disease patients with hypersplenism secondary to portal hypertension, yet large-scale data on postoperative complications remain scarce.Methods: A retrospective analysis was conducted on 986 Wilson's disease patients who underwent splenectomy between 2001 and 2019.Results: The overall postoperative complication rate was 68.7%, with bleeding, fever, and portal vein thrombosis occurring in 29.0%, 44.9%, and 20.5% of cases, respectively. Multivariable analysis identified hypersplenism grade as an independent risk factor for postoperative bleeding, abnormal liver function for postoperative fever, and lower alanine aminotransferase and albumin levels for portal vein thrombosis.Discussion: These findings suggest that preoperative evaluation of hypersplenism severity, liver function, and key laboratory markers can aid in surgical risk stratification and optimize perioperative management for Wilson's disease patients undergoing splenectomy.","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"39 1","pages":"2624150"},"PeriodicalIF":2.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146142757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Therapeutic Outcomes of Three Surgical Approaches for Acute Corneal Hydrops. 三种手术入路治疗急性角膜积液的疗效。

IF 2.7 4区医学

Journal of Investigative Surgery Pub Date : 2026-12-01 Epub Date: 2026-02-10 DOI: 10.1080/08941939.2026.2624147

Jie Bai, Shaowei Li, Chang Liu, Ling Li, Lin Zhao, Zexia Dou

{"title":"Therapeutic Outcomes of Three Surgical Approaches for Acute Corneal Hydrops.","authors":"Jie Bai, Shaowei Li, Chang Liu, Ling Li, Lin Zhao, Zexia Dou","doi":"10.1080/08941939.2026.2624147","DOIUrl":"10.1080/08941939.2026.2624147","url":null,"abstract":"Purpose: To compare therapeutic outcomes of three surgical approaches for acute corneal hydrops (ACH): compression sutures combined with intracameral air injection (CSAI), CSAI followed by deep anterior lamellar keratoplasty (DALK), and penetrating keratoplasty (PKP).Methods: This study enrolled 26 patients (26 eyes) into three groups: CSAI-only (7 eyes), CSAI+DALK (14 eyes), and PKP (5 eyes). Demographics; best-corrected visual acuity (BCVA), corneal edema area, central corneal thickness (CCT), corneal curvature during the acute phase; resolution time after CSAI; BCVA, corneal curvature, CCT, astigmatism at final follow-up; and complications were collected.Results: Mean corneal edema resolution time after CSAI was approximately 2 weeks. Postoperative BCVA (logMAR) improved in all groups (p < 0.05): CSAI-only (0.60 ± 0.15), CSAI+DALK (0.34 ± 0.16), PKP (0.15 ± 0.09). Among 17 eyes planned for DALK, Descemet's membrane perforation occurred in 5 eyes. One PKP case had graft rejection, no long-term complications in the other two groups.Conclusions: CSAI shortens ACH duration but offers limited visual improvement, serving as a phased treatment. DALK after CSAI resolution significantly improves BCVA and reduces graft rejection risk, making CSAI+DALK a preferred balanced approach. PKP provides the greatest BCVA but carries higher rejection risk, reserved for non-suitable cases of other options.","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"39 1","pages":"2624147"},"PeriodicalIF":2.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146149816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative Evaluation of Intraocular Lens Power Calculation Formulas in Patients After Radial Keratotomy. 桡骨角膜切开术患者人工晶状体度数计算公式的比较评价。

IF 2.7 4区医学

Journal of Investigative Surgery Pub Date : 2026-12-01 Epub Date: 2026-02-17 DOI: 10.1080/08941939.2026.2622155

Enjie Li, Zhenyu Wang, Yangfan Yu, Xijin Wu, Yuxuan Jia, Peilin Yue, Ting Chen, Qi Zhang, Xudong Song

{"title":"Comparative Evaluation of Intraocular Lens Power Calculation Formulas in Patients After Radial Keratotomy.","authors":"Enjie Li, Zhenyu Wang, Yangfan Yu, Xijin Wu, Yuxuan Jia, Peilin Yue, Ting Chen, Qi Zhang, Xudong Song","doi":"10.1080/08941939.2026.2622155","DOIUrl":"10.1080/08941939.2026.2622155","url":null,"abstract":"Objective: This study assessing the performance of five intraocular lens (IOL) calculation methodologies in cataract patients with previous radial keratotomy (RK) history.Methods: Five formulas predicted refractive outcomes, with prediction errors (PE) calculated by comparing formula-derived spherical equivalents to manifest refraction. Additional statistical analysis examined correlations between formula-specific PE and biometric parameters including axial length (AL) and corneal curvature.Results: Overall, Barrett True-K and Hoffer QST showed minimal prediction bias (PE: -0.06D and -0.07D; p > 0.05). PEARL-DGS had the best stability (SD: 0.97) and led in ±0.25D accuracy (20.8%, p = 0.665). In AL subgroups, Barrett True-K showed superior accuracy for medium-long eyes (26.0-30.0 mm; PE closest to zero), while EVO 2.0 yielded significant hyperopic error in short AL eyes (<26.0 mm). Significant negative correlations between flat keratometry and PE were identified for the Hoffer QST, Kane, and Pearl DGS formulas (all p < 0.01). In eyes with flat keratometry < 39.0 D, EVO 2.0, Kane, and Pearl DGS exhibited statistically significant hyperopic biases, while Barrett True-K and Hoffer QST maintained accuracy without systematic error.Conclusion: The results indicate that for post-RK patients, the Barrett True-K formula exhibits enhanced accuracy in IOL power calculation. Newer AI-based formulas show potential but currently remain limited by a systematic hyperopic bias in this population.","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"39 1","pages":"2622155"},"PeriodicalIF":2.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146213434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Remifentanil-Based Total Intravenous Anesthesia is Associated with Operating Room Extubation in Heart Transplantation: A Retrospective Matched Case-Control Study. 基于瑞芬太尼的全静脉麻醉与心脏移植手术室拔管相关：一项回顾性匹配病例-对照研究。

IF 2.7 4区医学

Journal of Investigative Surgery Pub Date : 2026-12-01 Epub Date: 2026-08-06 DOI: 10.1080/08941939.2026.2712671

Xue-Wen Zhou, Meng-Jing Yang, Peng Hao, Maxwell R Shen, Xia Zheng, Dian-San Su, Yong-Xing Yao

{"title":"Remifentanil-Based Total Intravenous Anesthesia is Associated with Operating Room Extubation in Heart Transplantation: A Retrospective Matched Case-Control Study.","authors":"Xue-Wen Zhou, Meng-Jing Yang, Peng Hao, Maxwell R Shen, Xia Zheng, Dian-San Su, Yong-Xing Yao","doi":"10.1080/08941939.2026.2712671","DOIUrl":"https://doi.org/10.1080/08941939.2026.2712671","url":null,"abstract":"Background: Immediate extubation after heart transplantation (IEAHT) may enhance postoperative recovery. However, factors associated with IEAHT and the impact of opioid exposure remain unknown. Building upon our favorable IEAHT experiences in a pediatric patient, we now examine the use of IEAHT in adult patients.Methods: This small, retrospective, exploratory case-control study (August 2018-March 2025) included 8 patients extubated in the operating room (case group) matched 1:3 to 24 patients extubated in the ICU (control group). Demographic data, operative characteristics, anesthetic techniques, and postoperative outcomes were collected and compared between the two groups.Results: Remifentanil-based TIVA was used more frequently in the case group (8/8, 100% vs. 6/24, 25%; p = 0.001). The case group had shorter cardiopulmonary bypass (median 105 vs. 155 min, p = 0.004) and operative times (249 vs. 329 min, p = 0.012). Among patients receiving remifentanil‑based TIVA, total opioid consumption did not differ between groups (p = 0.852). No significant inter-group differences were observed in postoperative complications or lengths of stay.Conclusion: In this exploratory cohort, remifentanil-based TIVA was associated with operating room extubation. Remifentanil-based TIVA may be feasible in selected patients, but its safety and efficacy require confirmation in adequately powered prospective randomized trials.","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"39 1","pages":"2712671"},"PeriodicalIF":2.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148678785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

History, Current State, and Future of Enhanced Recovery After Surgery (ERAS): In Commemoration of the 30th Anniversary of the ERAS Concept. 促进术后恢复（ERAS）的历史、现状和未来：纪念ERAS概念提出30周年。

IF 2.7 4区医学

Journal of Investigative Surgery Pub Date : 2026-12-01 Epub Date: 2026-06-01 DOI: 10.1080/08941939.2026.2675736

William Xu, Lifang Yang, Marc Basson

引用次数: 0

Research Progress on Lung Protection Measures During Prone Position Surgery. 俯卧位手术中肺保护措施的研究进展。

IF 2.7 4区医学

Journal of Investigative Surgery Pub Date : 2026-12-01 Epub Date: 2026-01-26 DOI: 10.1080/08941939.2026.2614674

Lantian Zhang, Qifan Bian, Yanlong Wang, Yaping Zhao, Peng Chen

{"title":"Research Progress on Lung Protection Measures During Prone Position Surgery.","authors":"Lantian Zhang, Qifan Bian, Yanlong Wang, Yaping Zhao, Peng Chen","doi":"10.1080/08941939.2026.2614674","DOIUrl":"10.1080/08941939.2026.2614674","url":null,"abstract":"The prone position is among the most frequently employed surgical positions in clinical practice. However, it can exert compression on the thoracic and abdominal regions, altering respiratory mechanics, such as a decrease in functional residual capacity, which inevitably results in some degree of ventilatory injury. Consequently, this raises the risk of postoperative pulmonary complications, which may increase patient mortality rates and extend hospital stays. Beyond conventional lung-protective ventilation strategies, certain pharmacological interventions and intraoperative fluid management measures have also been shown to provide lung protection. However, most related studies have focused on the supine position. Since the prone position can affect respiratory mechanics and the circulatory system to some extent, the effects of certain measures when applied in the prone position may differ. This narrative review examines the efficacy and potential implications of current lung-protective measures in the prone position, offering guidance on lung protection for patients undergoing general anesthesia and prone position surgery.","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"39 1","pages":"2614674"},"PeriodicalIF":2.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146046899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hsa_Circ_0036763 is a Prognostic Biomarker for Intervertebral Disc Degeneration and Affects the Senescence and Collagen Loss of Nucleus Pulposus Cells via miR-4741/RGSL1. Hsa_Circ_0036763是椎间盘退变的预后生物标志物，通过miR-4741/RGSL1影响髓核细胞的衰老和胶原流失。

IF 2.7 4区医学

Journal of Investigative Surgery Pub Date : 2026-12-01 Epub Date: 2026-04-29 DOI: 10.1080/08941939.2026.2656577

Yuanbin Zhang, Chaohua Li, Xiaoming Hong, Weiye Chen, Xingzhong Hu

{"title":"Hsa_Circ_0036763 is a Prognostic Biomarker for Intervertebral Disc Degeneration and Affects the Senescence and Collagen Loss of Nucleus Pulposus Cells via miR-4741/RGSL1.","authors":"Yuanbin Zhang, Chaohua Li, Xiaoming Hong, Weiye Chen, Xingzhong Hu","doi":"10.1080/08941939.2026.2656577","DOIUrl":"10.1080/08941939.2026.2656577","url":null,"abstract":"Background: Intervertebral disk degeneration (IDD) is a degenerative disease mainly characterized by intervertebral disk tissue senescence and collagen loss. The role of hsa_circ_0036763 in IDD remains incompletely understood.Methods: The clinical value of hsa_circ_0036763 was explored by retrospectively analyzing the serum samples of 120 IDD patients through ROC curve, Kaplan-Meier curve, and Cox proportional hazards analysis. The severity of IDD was distinguished through the modified Pfirrmann grading system. The downstream regulatory mechanism (miR-4741/RGSL1) of hsa_circ_0036763 was mined through the miRDB and TargetScan databases, and their targeting relationships were demonstrated by the dual-luciferase reporter and RNA pull-down assays. The IL-1β-induced senescent nucleus pulposus cells (NPCs) were used to evaluate the potential role of hsa_circ_0036763/miR-4741/RGSL1 axis in IDD progression.Results: Serum hsa_circ_0036763 expression was negatively correlated with the modified Pfirrmann grade of IDD patients (r = -0.675). Its low expression predicted a higher risk of IDD recurrence (HR = 0.252, p = 0.002). Hsa_circ_0036763 sponged miR-4741, thereby relieving its inhibition on RGSL1 expression. Exogenous overexpression of hsa_circ_0036763 alleviated the senescence, collagen loss, and oxidative stress in IL-1β-induced NPCs, which were reversed by co-transfection of miR-4741 mimics and silencing of RGSL1.Conclusion: Hsa_circ_0036763 may serve as a prognostic marker for IDD and participates in IDD-related NPC degeneration by regulating miR-4741/RGSL1.","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"39 1","pages":"2656577"},"PeriodicalIF":2.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147773811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impaired Pancreatic Drainage as a Potential Key Mechanism in Postpancreatectomy Hemorrhage: A Retrospective Cohort Study. 胰腺引流受损是胰腺切除术后出血的潜在关键机制：一项回顾性队列研究。

IF 3.5 4区医学

Journal of Investigative Surgery Pub Date : 2026-12-01 Epub Date: 2026-06-02 DOI: 10.1080/08941939.2026.2679350

Shixing Wu, Atigu Abuduwaili, Cheng Wang, Bolin Zhang, Jiangang Li, Paerhatijiang Abulimiti, Yindala Ba, Dilixiati Tuniyazi, Cheng Geng, Zhaohui Tang, Xinjian Xu

{"title":"Impaired Pancreatic Drainage as a Potential Key Mechanism in Postpancreatectomy Hemorrhage: A Retrospective Cohort Study.","authors":"Shixing Wu, Atigu Abuduwaili, Cheng Wang, Bolin Zhang, Jiangang Li, Paerhatijiang Abulimiti, Yindala Ba, Dilixiati Tuniyazi, Cheng Geng, Zhaohui Tang, Xinjian Xu","doi":"10.1080/08941939.2026.2679350","DOIUrl":"10.1080/08941939.2026.2679350","url":null,"abstract":"Background: Postoperative pancreatic fistula (POPF) is recognized as the main cause of postpancreatectomy hemorrhage (PPH). This study investigated the correlation between POPF and PPH after pancreatoduodenectomy (PD).Methods: We retrospectively analyzed PDs at our center from January 2005 to December 2023. We documented patient characteristics, surgical factors, and outcomes and did a multivariate analysis of PPH.Results: Among 659 PD patients, the overall PPH incidence was 9.3% (n = 62), with 85.5% having late PPH. The PPH group had higher POPF rates, especially Grade B/C POPF. The PPH group also had higher postoperative pancreatic fluid accumulation on day 5 and a higher incidence of sustained peak amylase levels in the drainage fluid. Multivariate analysis showed intraoperative blood loss >1,000 mL, clinically relevant - POPF, and postoperative intra - abdominal infection as independent risk factors for late PPH.Conclusion: Grade B/C POPF, significant intraoperative blood loss, and postoperative intra - abdominal infection are independently associated with late PPH. POPF may not be the only cause of PPH. Our findings suggest impaired pancreatic drainage may contribute to PPH, but this needs prospective validation.","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"39 1","pages":"2679350"},"PeriodicalIF":3.5,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148143615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Retrospective Comparative Study on the Omission Versus Placement of Chest Drain Following Thoracoscopic Sublobar Resection. 胸腔镜肺叶下切除术后胸腔引流遗漏与放置的回顾性比较研究。

IF 2.7 4区医学

Journal of Investigative Surgery Pub Date : 2026-12-01 Epub Date: 2026-02-18 DOI: 10.1080/08941939.2026.2624332

Yunhong Xu, Yu Zhou, Jiahao Shen, Sishi Huang, Qinhua Gu, Weiwei Min, Lili Jin, Qibin Shen

{"title":"A Retrospective Comparative Study on the Omission Versus Placement of Chest Drain Following Thoracoscopic Sublobar Resection.","authors":"Yunhong Xu, Yu Zhou, Jiahao Shen, Sishi Huang, Qinhua Gu, Weiwei Min, Lili Jin, Qibin Shen","doi":"10.1080/08941939.2026.2624332","DOIUrl":"10.1080/08941939.2026.2624332","url":null,"abstract":"Purpose: This study aims to investigate the clinical applicability of omitting chest drainage tube following thoracoscopic sublobar resection.Methods: We gathered data from 1,054 patients who met the inclusion criteria and underwent thoracoscopic sublobar resection at the Thoracic Surgery Department of Huzhou Central Hospital between January 2023 and December 2024. Using propensity score matching, a total of 488 patients were ultimately chosen as the study participants. Key outcome measures included postoperative analgesic consumption, incidence of pneumothorax, pleural effusion, inflammatory markers, re-drainage rate, pneumothorax following tube removal, average hospitalization costs, and average length of hospital stay.Results: The no-drain cohort exhibited notable benefits: the mean duration of hospitalization was reduced by 1.02 days (2.48 ± 0.93 vs. 3.50 ± 1.46, p < 0.001), and healthcare expenditures decreased by 9.4% (23284.80 ± 3556 vs. 25706.39 ± 4443, p < 0.001). A significant difference was observed in the utilization of pain pumps (8.2% vs. 87.7%, p < 0.001). Additionally, 28 cases (11.47%) in the no-tube group experienced lung compression between 20% and 40%, compared to 9 cases (3.68%) in the tube group. Furthermore, 11 cases (4.91%) in the no-tube group had lung compression greater than 40%, whereas the tube group had only 3 cases (1.22%). The incidence of severe complications in both groups remained below 1.5%.Conclusion: The implementation of a no-drain approach following thoracoscopic sublobar resection effectively reduces hospital stay, duration and medical costs without exacerbating inflammatory responses.","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"39 1","pages":"2624332"},"PeriodicalIF":2.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146219967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0