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Demographic characteristics and self-reported motivations of women undergoing genital aesthetic surgery: A descriptive cohort of 927 patients in Turkey (2017-2024). 接受生殖器美容手术的女性的人口统计学特征和自我报告的动机:土耳其927名患者的描述性队列(2017-2024)。
IF 1.8 4区 医学
Journal of International Medical Research Pub Date : 2026-09-01 Epub Date: 2026-09-17 DOI: 10.1177/03000605261487263
Ayse Konac
{"title":"Demographic characteristics and self-reported motivations of women undergoing genital aesthetic surgery: A descriptive cohort of 927 patients in Turkey (2017-2024).","authors":"Ayse Konac","doi":"10.1177/03000605261487263","DOIUrl":"https://doi.org/10.1177/03000605261487263","url":null,"abstract":"<p><p>ObjectiveGenital aesthetic surgery, within the broader domain of female genital cosmetic surgery, has become increasingly visible in clinical practice. However, descriptive data on patient characteristics and self-reported motivations remain limited. This study describes the demographic profile, psychosocial context, motivations, and procedural patterns among women undergoing genital aesthetic surgery in Turkey.MethodsThis descriptive cohort included 927 consecutive women who underwent genital aesthetic surgery between 2017 and 2024. Data were collected during clinical evaluation using a structured questionnaire and medical records, including lifestyle factors, partner-related decision context, psychiatric history markers, motivations, procedure type, and post-treatment status. Analyses were purely descriptive, with continuous variables reported as mean ± SD and median.ResultsThe mean age was 42.0 ± 12.4 years, and 62.4% were married. Educational attainment most commonly reflected an associate degree (45.5%). Current smoking was reported by 629 of 927 participants (67.9%), alcohol use by 32.4%, and a history of prior cosmetic surgery by 33.1%. A psychiatric diagnosis was documented in 10.0%, and psychiatric medication use in 11.4%. Partner involvement was frequent: 64.2% presented at their spouse's request; decisions were self-driven in 53.0%, partner-driven in 32.6%, and joint in 14.5%. The most commonly endorsed motivations were personal aesthetic concern (63.0%) and relationship anxiety/relationship repair (38.0%). The most frequent procedures were perineoplasty + vaginoplasty (24.3%). Recorded post-treatment status was categorized as successful in 76.9%, with wound-healing problems (9.8%) and unrealistic expectations (6.0%) among the most common nonsuccess categories.ConclusionIn this large descriptive cohort, genital aesthetic surgery was commonly pursued in mid-adulthood and often occurred within partner-related decision-making contexts, with motivations frequently spanning aesthetic, relational, and functional domains. These findings support the clinical importance of autonomy-sensitive counseling, expectation management, and structured psychosocial documentation in routine genital aesthetic surgery care.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"54 9","pages":"3000605261487263"},"PeriodicalIF":1.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148990348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between serum 25-hydroxyvitamin D and visceral fat area in adults with type 2 diabetes: A cross-sectional study. 成人2型糖尿病患者血清25-羟基维生素D与内脏脂肪面积的关系:一项横断面研究
IF 1.8 4区 医学
Journal of International Medical Research Pub Date : 2026-09-01 Epub Date: 2026-09-16 DOI: 10.1177/03000605261487246
Junling Zhu, Xujie Tang, Chunyan Zhu, Yiming Zhang, Zichen Rao, Qianru Zhu, Lulu Zheng
{"title":"Association between serum 25-hydroxyvitamin D and visceral fat area in adults with type 2 diabetes: A cross-sectional study.","authors":"Junling Zhu, Xujie Tang, Chunyan Zhu, Yiming Zhang, Zichen Rao, Qianru Zhu, Lulu Zheng","doi":"10.1177/03000605261487246","DOIUrl":"https://doi.org/10.1177/03000605261487246","url":null,"abstract":"<p><p>ObjectiveTo examine the association between serum 25-hydroxyvitamin D and visceral fat area in adults with type 2 diabetes and assess the exposure-response pattern.MethodsThis retrospective cross-sectional study included 1271 adults with type 2 diabetes. Serum 25-hydroxyvitamin D was analyzed as a continuous variable and by quartiles. Multivariable linear regression models were sequentially adjusted for demographic, lifestyle, and metabolic factors, with body mass index added separately in the fully adjusted model. A generalized additive model was used to assess the exposure-response relationship. Prespecified subgroup analyses were also performed.ResultsVisceral fat area differed across quartiles of serum 25-hydroxyvitamin D, with a lower median value in Q4 than in Q1 (87.0 vs. 96.0 cm<sup>2</sup>; p = 0.002). Higher serum 25-hydroxyvitamin D was associated with lower visceral fat area in the multivariable model without body mass index (β = -0.77, 95% confidence interval: -1.13 to -0.41; p < 0.0001) and in the body mass index-adjusted model (β = -0.53, 95% confidence interval: -0.80 to -0.27; p < 0.0001). In quartile analyses, participants in Q4 had lower visceral fat area than those in Q1 in the body mass index-adjusted model (β = -10.04, 95% confidence interval: -16.19 to -3.89; p = 0.0015), whereas the associations for Q2 and Q3 were not statistically significant; nevertheless, a significant trend was observed across quartiles (p for trend = 0.0005). The generalized additive model suggested an approximately linear inverse association between serum 25-hydroxyvitamin D and visceral fat area.ConclusionsIn adults with type 2 diabetes, higher serum 25-hydroxyvitamin D levels were associated with lower HDS-2000-estimated visceral fat area, although the association was attenuated after adjustment for body mass index. This cross-sectional association should not be interpreted as independent of overall adiposity or unmeasured lifestyle, comorbidity, and treatment-related factors. Longitudinal studies are needed to clarify temporality.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"54 9","pages":"3000605261487246"},"PeriodicalIF":1.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148976897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Barriers and evidence-informed strategies for the high-quality development of drug clinical trials in Anhui Province, central China: A cross-sectional survey. 安徽省药物临床试验高质量发展的障碍和循证策略:一项横断面调查。
IF 1.8 4区 医学
Journal of International Medical Research Pub Date : 2026-09-01 Epub Date: 2026-09-16 DOI: 10.1177/03000605261485068
Xiaobei Liu, Liying Ren, Dongmei Deng, Rui Chen, Fangyi Xu, Huan Zhou, Hongtao Li, Jianzhong Shentu
{"title":"Barriers and evidence-informed strategies for the high-quality development of drug clinical trials in Anhui Province, central China: A cross-sectional survey.","authors":"Xiaobei Liu, Liying Ren, Dongmei Deng, Rui Chen, Fangyi Xu, Huan Zhou, Hongtao Li, Jianzhong Shentu","doi":"10.1177/03000605261485068","DOIUrl":"https://doi.org/10.1177/03000605261485068","url":null,"abstract":"<p><p>ObjectiveTo investigate the current status, challenges, and development needs of the drug clinical trial industry in Anhui Province, central China, and to provide empirical evidence to support its high-quality development.MethodsThis cross-sectional study administered a questionnaire survey to 453 practitioners across multiple drug clinical trial institutions in Anhui Province (crude response rate, 63.9%; valid response rate, 62.9%). The survey collected data on demographic characteristics, work-related factors, perceived barriers and facilitators, and job satisfaction. Descriptive statistics, subgroup comparisons with Bonferroni correction, and ordinal logistic regression were used for data analysis.ResultsClinical research coordinators accounted for 32.01% of respondents, whereas biorepository managers accounted for only 0.44%. Respondents with a pharmacy background comprised 41.72%, whereas those with a clinical medicine background accounted for 30.46%. Only 54.30% of respondents reported proficiency in operating electronic data capture systems. The main reported challenges included difficulty recruiting trial participants (77.70%), low public awareness (68.21%), and insufficient self-reported digital literacy among practitioners (48.34%). A total of 90.29% of respondents supported the establishment of clinical trial-related academic programs in higher medical education. Improving professional competency was identified as the most important measure (76.38%), followed by optimizing regulatory systems (12.80%). Overall, 69.09% of practitioners reported satisfaction with their career development.ConclusionClinical trial practitioners in Anhui Province face prominent challenges, including difficulties in participant recruitment, an imbalanced workforce structure across job roles, insufficient digital literacy, and complex management processes. Based on these findings, several evidence-informed directions are proposed: strengthening public education, optimizing talent training, promoting digital infrastructure development, and enhancing regional coordination. These measures may facilitate the high-quality development of drug clinical trials in Anhui Province, central China.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"54 9","pages":"3000605261485068"},"PeriodicalIF":1.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148976841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and validation of a nomogram for predicting catheter-related complications after percutaneous transhepatic cholangial drainage in malignant obstructive jaundice patients: A retrospective study. 恶性梗阻性黄疸患者经皮肝胆管引流术后导管相关并发症预测图的建立和验证:一项回顾性研究。
IF 1.8 4区 医学
Journal of International Medical Research Pub Date : 2026-09-01 Epub Date: 2026-09-17 DOI: 10.1177/03000605261487260
Xin Wang, Jixian Zang, Xiaoyang Su, Aomei Li
{"title":"Development and validation of a nomogram for predicting catheter-related complications after percutaneous transhepatic cholangial drainage in malignant obstructive jaundice patients: A retrospective study.","authors":"Xin Wang, Jixian Zang, Xiaoyang Su, Aomei Li","doi":"10.1177/03000605261487260","DOIUrl":"https://doi.org/10.1177/03000605261487260","url":null,"abstract":"<p><p>ObjectiveTo identify predictors of 30-day catheter-related complications after percutaneous transhepatic cholangial drainage in patients with malignant obstructive jaundice and to develop and internally validate an individualized risk-prediction nomogram.MethodsThis single-center retrospective study included consecutive patients with malignant obstructive jaundice who underwent percutaneous transhepatic cholangial drainage between January 2020 and December 2025. The primary outcome was the occurrence of catheter-related complications within 30 days after percutaneous transhepatic cholangial drainage. Univariable and multivariable logistic regression analyses were used to identify candidate predictors and construct the final model. Model performance was assessed using the area under the receiver operating characteristic curve, calibration analysis, the Hosmer-Lemeshow goodness-of-fit test, the Brier score, decision curve analysis, and bootstrap internal validation with 1000 resamples.ResultsA total of 380 patients were included, of whom 122 (32.1%) developed catheter-related complications within 30 days. The final model incorporated prior biliary intervention, high biliary obstruction, ascites, C-reactive protein level, bilateral drainage, and catheter size. Prior biliary intervention (adjusted odds ratio = 2.06; 95% confidence interval: 1.24-3.42), ascites (adjusted odds ratio = 1.88; 95% confidence interval: 1.12-3.15), and higher C-reactive protein level (adjusted odds ratio per 10 mg/L increase, 1.19; 95% confidence interval: 1.09-1.30) were associated with an increased risk of complications, whereas larger catheter size was associated with a lower risk (adjusted odds ratio per 2-Fr increase, 0.60; 95% confidence interval: 0.40-0.92). The nomogram achieved an area under the receiver operating characteristic curve of 0.710, an optimism-corrected area under the receiver operating characteristic curve of 0.688, and a Brier score of 0.192. Calibration was satisfactory, with no evidence of poor fit (Hosmer-Lemeshow p = 0.923). Decision curve analysis indicated potential clinical net benefit across relevant threshold probabilities.ConclusionsCatheter-related complications were common after percutaneous transhepatic cholangial drainage. A nomogram based on routinely available clinical, inflammatory, and procedural variables showed acceptable internal performance and may assist in the early identification and targeted management of patients at high risk.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"54 9","pages":"3000605261487260"},"PeriodicalIF":1.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148990343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Value of shear wave elastography in evaluating response to neoadjuvant chemotherapy in breast cancer: A systematic review and meta-analysis. 剪切波弹性成像评价乳腺癌新辅助化疗疗效的价值:一项系统综述和荟萃分析。
IF 1.8 4区 医学
Journal of International Medical Research Pub Date : 2026-09-01 Epub Date: 2026-09-03 DOI: 10.1177/03000605261474642
Bin Lian, Chuanxin Ye, Fengjie Li, Huotang Qin, Lifang Zhou, Changyuan Wei, Huihui Yang
{"title":"Value of shear wave elastography in evaluating response to neoadjuvant chemotherapy in breast cancer: A systematic review and meta-analysis.","authors":"Bin Lian, Chuanxin Ye, Fengjie Li, Huotang Qin, Lifang Zhou, Changyuan Wei, Huihui Yang","doi":"10.1177/03000605261474642","DOIUrl":"10.1177/03000605261474642","url":null,"abstract":"<p><p>ObjectiveTo determine how well shear wave elastography performs as a diagnostic tool for determining the pathological response to neoadjuvant chemotherapy in breast cancer.MethodsThrough April 2025, a systematic search of PubMed, MEDLINE, Cochrane Library, China National Knowledge Infrastructure, and SinoMed was used to perform a diagnostic meta-analysis. Included were studies of individuals with breast cancer receiving neoadjuvant chemotherapy with shear wave elastography evaluation. The diagnostic performance of shear wave elastography was assessed using a hierarchical summary receiver operating characteristic model and a bivariate random-effects model. The Quality Assessment of Diagnostic Accuracy Studies-2 was used to evaluate the quality of the study.ResultsThe study includes 15 trials with 1402 patients. For predicting pathological response to neoadjuvant chemotherapy, the pooled sensitivity and specificity of shear wave elastography were 0.68 (95% confidence intervals: 0.49-0.86) and 0.73 (95% confidence intervals: 0.60-0.87), respectively. 13.06 (95% confidence intervals: 8.42-20.25) was the pooled diagnostic odds ratio. The hierarchical summary receiver operating characteristic study showed a moderate diagnostic performance with an area under the curve of 0.85 (95% confidence intervals: 0.82-0.88).ConclusionsShear wave elastography may be a helpful supplementary imaging modality in clinical treatment monitoring and showed moderate diagnostic performance for assessing pathological response to neoadjuvant chemotherapy in breast cancer. To confirm its clinical value, more extensive prospective investigations are required. PROSPERO registration number: CRD420261435666.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"54 9","pages":"3000605261474642"},"PeriodicalIF":1.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13546472/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148887529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Computed tomography-guided precision biopsy combined with metagenomic next-generation sequencing for etiological diagnosis in patients with blood culture-negative systemic infections. 计算机断层扫描引导下的精确活检结合新一代宏基因组测序用于血液培养阴性全身性感染患者的病因诊断。
IF 1.8 4区 医学
Journal of International Medical Research Pub Date : 2026-09-01 Epub Date: 2026-09-04 DOI: 10.1177/03000605261481695
Yongkun Fang, Chenglin Fan, Pingping Liu, Shengping Wang, Wei Zhang
{"title":"Computed tomography-guided precision biopsy combined with metagenomic next-generation sequencing for etiological diagnosis in patients with blood culture-negative systemic infections.","authors":"Yongkun Fang, Chenglin Fan, Pingping Liu, Shengping Wang, Wei Zhang","doi":"10.1177/03000605261481695","DOIUrl":"10.1177/03000605261481695","url":null,"abstract":"<p><p>ObjectiveTo evaluate the diagnostic efficacy of computed tomography-guided percutaneous biopsy combined with metagenomic next-generation sequencing in patients with blood culture-negative systemic infections and to assess the clinical impact of using this combined strategy for etiological confirmation and guidance of targeted antimicrobial therapy.MethodsThis single-center retrospective observational cohort study enrolled 78 patients who met the Sepsis-3 consensus criteria for suspected systemic infection and had negative conventional microbiological work-ups (at least two sets of blood cultures) between April 2022 and March 2025. All patients underwent computed tomography-guided biopsy of radiologically identified infectious foci, with specimens processed concurrently for conventional culture and metagenomic next-generation sequencing. Diagnostic performance was benchmarked against the final comprehensive clinical diagnosis, and the influence of metagenomic next-generation sequencing findings on antimicrobial therapy modification was analyzed. Sample size calculation, based on a prior study estimating an metagenomic next-generation sequencing detection rate of 85% (α = 0.05, β = 0.2), indicated a minimum of 68 cases; accordingly, 78 patients were enrolled.ResultsComputed tomography-guided biopsy was technically successful in all 78 patients (100%). The pathogen detection rate of metagenomic next-generation sequencing (91.0%, 71/78) was significantly higher than that of conventional culture (55.1%, 43/78; <i>p</i> < 0.001). Using the final clinical diagnosis as the reference standard, metagenomic next-generation sequencing achieved a sensitivity of 94.7% (95% confidence interval: 86.9-98.5), specificity of 100.0% (95% confidence interval: 29.2-100.0), positive predictive value of 100.0% (95% confidence interval: 94.9-100.0), and negative predictive value of 42.9% (95% confidence interval: 9.9-81.6). Among the 35 culture-negative specimens, metagenomic next-generation sequencing established a definitive microbiological diagnosis in 28 cases (80.0%) and detected polymicrobial infections in 11 cases (14.1% of the cohort). Antimicrobial therapy was rationally adjusted based on metagenomic next-generation sequencing results in 69.2% (54/78) of the patients.ConclusionsThe integration of computed tomography-guided precision biopsy with metagenomic next-generation sequencing offers a highly effective diagnostic approach for blood culture-negative systemic infections. This synergistic strategy improves etiological diagnosis by providing high-yield target specimens that enable comprehensive, unbiased pathogen screening, facilitates differentiation between infectious and non-infectious etiologies, and supplies critical evidence for guiding precision antimicrobial therapy. These findings highlight the growing role of interventional radiology in the contemporary framework of precision infectious disease management.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"54 9","pages":"3000605261481695"},"PeriodicalIF":1.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13554516/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polypharmacy and patterns of medication use in the final year of life among people living with dementia in Canada: A case-control study. 加拿大痴呆症患者生命最后一年的多种用药和用药模式:一项病例对照研究。
IF 1.8 4区 医学
Journal of International Medical Research Pub Date : 2026-09-01 Epub Date: 2026-09-27 DOI: 10.1177/03000605261487270
Jasmine Mah, Catherine Richer, Abby Emdin, Kenneth Rockwood, Samuel Stewart, Melissa K Andrew, Shanna C Trenaman
{"title":"Polypharmacy and patterns of medication use in the final year of life among people living with dementia in Canada: A case-control study.","authors":"Jasmine Mah, Catherine Richer, Abby Emdin, Kenneth Rockwood, Samuel Stewart, Melissa K Andrew, Shanna C Trenaman","doi":"10.1177/03000605261487270","DOIUrl":"https://doi.org/10.1177/03000605261487270","url":null,"abstract":"<p><p>ObjectiveAt the end of life, changing healthcare needs may lead to decreased use of preventive therapies and increased use of medications for symptom management. This study compared polypharmacy, hyperpolypharmacy, and medication-dispensing patterns among community-dwelling older adults with dementia, community-dwelling older adults without dementia, and older adults with dementia in long-term care.MethodsWe completed a retrospective, matched case-control study using linked administrative health data from Nova Scotia, Canada. We compared polypharmacy, hyperpolypharmacy, and medications dispensed among three groups (community-dwelling older adults with dementia, community-dwelling older adults without dementia, and older adults with dementia in long-term care). We chose community-dwelling older adults with dementia with dates of death between 1 January 2019 and 1 January 2021, and then matched with replacement to community-dwelling older adults without dementia and older adults with dementia in long-term care based on age, administrative sex, and date of death ±30 days. Descriptive comparisons of polypharmacy, hyperpolypharmacy, and medications used during each of three equal periods of the last year of life (early, mid, and late) were made. Logistic regression was used to estimate the probability of polypharmacy and hyperpolypharmacy, adjusting for demographic and clinical factors.ResultsEach group included 1274 individuals. The mean age was 84.8 years. Overall, 50.9% (1944/3822) experienced polypharmacy and 8.7% (332/3822) hyperpolypharmacy, with community-dwelling older adults with dementia consistently having the highest rates. The most common medications dispensed in the last year of life were furosemide, levothyroxine sodium, salbutamol, and vitamin B12.ConclusionsCommunity-dwelling older adults with dementia had the highest rates of polypharmacy and hyperpolypharmacy across all time periods assessed. Medications most frequently dispensed in the last year of life did not change in ways that would be expected if deprescribing recommendations were being followed. This suggests that prescribing and deprescribing at the end of life are potential areas for pharmacist support and involvement.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"54 9","pages":"3000605261487270"},"PeriodicalIF":1.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149069770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of resistant starch on blood pressure and autonomic function in women with the risk of metabolic syndrome: A randomized double-blind pilot study. 抗淀粉对有代谢综合征风险的女性血压和自主神经功能的影响:一项随机双盲先导研究
IF 1.8 4区 医学
Journal of International Medical Research Pub Date : 2026-09-01 Epub Date: 2026-09-17 DOI: 10.1177/03000605261477885
Seok-Hoon Lee, Hyang-Rae Lee, Min-Sook Kang, Yong-Ju Lee, Seyoung Ju, Sang-Hoon Lee, Nam-Seok Joo
{"title":"Effects of resistant starch on blood pressure and autonomic function in women with the risk of metabolic syndrome: A randomized double-blind pilot study.","authors":"Seok-Hoon Lee, Hyang-Rae Lee, Min-Sook Kang, Yong-Ju Lee, Seyoung Ju, Sang-Hoon Lee, Nam-Seok Joo","doi":"10.1177/03000605261477885","DOIUrl":"10.1177/03000605261477885","url":null,"abstract":"<p><p>ObjectiveResistant starch is associated with metabolic benefits, but whether autonomic regulation links resistant starch intake to cardiovascular outcomes remains unclear. This study examined the effects of resistant starch on heart rate variability and blood pressure in women with features of metabolic syndrome.MethodsIn this 8-week randomized, double-blind pilot trial, 30 women (aged ≥ 40 years) with ≥2 metabolic syndrome components were assigned to a high-resistant starch or low-resistant starch group. The primary outcome was the change in systolic blood pressure from baseline to week 8. Secondary outcomes included heart rate variability-related autonomic parameters, whereas other blood pressure and metabolic syndrome-related variables were evaluated as exploratory outcomes.ResultsSystolic blood pressure decreased significantly within the high-resistant starch group (p = 0.037), although the baseline-adjusted between-group difference was not statistically significant. This change occurred without corresponding improvements in body mass index or triglyceride levels. Group-level heart rate variability differences did not reach statistical significance; however, exploratory analyses suggested a favorable directional pattern in global heart rate variability composite scores among participants with lower baseline autonomic activity (p = 0.06).ConclusionsHigh-resistant starch intake demonstrated exploratory signals of reduced systolic blood pressure and heart rate variability-related autonomic adaptation, particularly among participants with lower baseline autonomic activity. These findings warrant confirmation in adequately powered randomized controlled trials.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"54 9","pages":"3000605261477885"},"PeriodicalIF":1.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148990361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The use of artificial intelligence and wearable devices in enhanced recovery after surgery pathways following radical cystectomy: A systematic review. 人工智能和可穿戴设备在根治性膀胱切除术后增强术后恢复中的应用:一项系统综述。
IF 1.8 4区 医学
Journal of International Medical Research Pub Date : 2026-09-01 Epub Date: 2026-09-16 DOI: 10.1177/03000605261485388
Matthew Feyissa, Yama Baheer, Buraq Ahmed, Natacha Rosa, Shiv Dubey, Karthig Thillaivasan, Yiannis Philippou, Rakan Odeh, Muheilan Muheilan, Pramit Khetrapal, James Wf Catto, John D Kelly, Mallikarjuna Chiruvella, Nikhil Vasdev
{"title":"The use of artificial intelligence and wearable devices in enhanced recovery after surgery pathways following radical cystectomy: A systematic review.","authors":"Matthew Feyissa, Yama Baheer, Buraq Ahmed, Natacha Rosa, Shiv Dubey, Karthig Thillaivasan, Yiannis Philippou, Rakan Odeh, Muheilan Muheilan, Pramit Khetrapal, James Wf Catto, John D Kelly, Mallikarjuna Chiruvella, Nikhil Vasdev","doi":"10.1177/03000605261485388","DOIUrl":"10.1177/03000605261485388","url":null,"abstract":"<p><p>ObjectiveRadical cystectomy is associated with relatively high rates of 90-day complications (58%-66%) and readmission (40%). The increasing availability of wearable devices, such as Fitbit devices, Misfit trackers and SenseWear armbands, may offer opportunities to improve postoperative outcomes. This review aimed to explore the roles of wearable devices and artificial intelligence in the perioperative care of patients undergoing radical cystectomy.MethodsA systematic review (PROSPERO: CRD420261279062) was conducted to investigate the role of wearable devices and artificial intelligence in enhanced recovery protocols following radical cystectomy. A total of 1031 studies were identified from 5 databases, of which 42 underwent full-text screening. Following final eligibility assessment, eight studies were included in the systematic review. Extracted postoperative outcomes included step count, length of stay, readmission, discharge location, body mass index, functional measures and postoperative complications.ResultsSeven studies investigated wearable devices, whereas one study examined the use of artificial intelligence to assess the association between body composition and postoperative complications. Preliminary evidence suggested that wearable devices improve postoperative physical activity and step counts; however, the significance of these associations varied substantially across studies. Evidence regarding artificial intelligence was limited to preoperative planning but indicated potential for identifying patients at high or low risk of complications following radical cystectomy.ConclusionsPreliminary evidence suggests that wearable devices and artificial intelligence provide useful information to support postoperative recovery. However, the limited number of studies precludes firm conclusions. Randomised trials using standardised parameters are needed to establish the roles of wearable devices and artificial intelligence before their clinical integration into established enhanced recovery after surgery protocols.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"54 9","pages":"3000605261485388"},"PeriodicalIF":1.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148982844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical impact of radial artery rupture during percutaneous transluminal angioplasty for radiocephalic arteriovenous fistula dysfunction: A single-center retrospective study. 经皮腔内血管成形术治疗放射性头动静脉瘘功能障碍时桡动脉破裂的临床影响:一项单中心回顾性研究。
IF 1.8 4区 医学
Journal of International Medical Research Pub Date : 2026-09-01 Epub Date: 2026-09-04 DOI: 10.1177/03000605261480900
Jun Yin, Jinxi Wei, Li Fu, Wei Wang, Fengping Wang
{"title":"Clinical impact of radial artery rupture during percutaneous transluminal angioplasty for radiocephalic arteriovenous fistula dysfunction: A single-center retrospective study.","authors":"Jun Yin, Jinxi Wei, Li Fu, Wei Wang, Fengping Wang","doi":"10.1177/03000605261480900","DOIUrl":"10.1177/03000605261480900","url":null,"abstract":"<p><p>ObjectiveTo evaluate the long-term patency outcomes of radiocephalic arteriovenous fistulas treated with percutaneous transluminal angioplasty for radial artery stenosis, with a particular focus on the clinical impact of percutaneous transluminal angioplasty-induced radial artery rupture and its endovascular management.MethodsThis single-center retrospective analysis involved all patients diagnosed with arteriovenous fistula dysfunction and radial artery stenosis who were treated with arterial percutaneous transluminal angioplasty at our department from January 2021 to September 2024. In total, 56 patients were ultimately included in the study.ResultsTechnical success was achieved in all patients. Radial artery rupture occurred in 10 of the 56 patients (17.86%) during percutaneous transluminal angioplasty and was successfully managed using prolonged low-pressure balloon inflation combined with localized external compression, without the need for covered stent implantation or surgical repair. At 1 year, primary patency rates were 40.0% in the rupture group and 39.1% in the normal group (<i>p</i> = 0.53), whereas the corresponding secondary patency rates were 90.0% and 87.0%, respectively (<i>p</i> = 0.35).ConclusionPercutaneous transluminal angioplasty is an effective treatment for radiocephalic arteriovenous fistula dysfunction caused by radial artery stenosis. Although dilation-induced radial artery rupture was relatively common in our cohort, it may be safely managed with prolonged low-pressure balloon inflation and localized compression without routine stent implantation or surgical intervention. Importantly, radial artery rupture did not appear to compromise long-term access-circuit patency. These findings apply to overall access-circuit outcomes rather than lesion-level durability. Controlled arterial rupture during percutaneous transluminal angioplasty appears to be a manageable procedural event that was not associated with worse overall access-circuit outcomes in this cohort.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"54 9","pages":"3000605261480900"},"PeriodicalIF":1.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13546462/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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