Journal of International Medical Research最新文献

{"title":"Retraction.","authors":"","doi":"10.1177/03000605251382308","DOIUrl":"10.1177/03000605251382308","url":null,"abstract":"","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 9","pages":"3000605251382308"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12511709/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145244633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accessory cavitated uterine malformation in a perimenopausal woman: Case report and literature review.","authors":"Yuan Zhang, Hanxue Lv, Congjie Lin, Hua Liu","doi":"10.1177/03000605251372459","DOIUrl":"10.1177/03000605251372459","url":null,"abstract":"<p><p>Accessory cavitated uterine malformation is a rare congenital anomaly of Müllerian duct development that typically affects younger women of reproductive age. The most common symptoms include chronic cyclic pelvic pain and severe dysmenorrhea, although diagnosis is frequently delayed owing to its rarity, multiple differential diagnoses, and low patient awareness. This report describes the case of a perimenopausal woman with accessory cavitated uterine malformation. The patient exhibited a palpable mass in the right lower abdomen without notable chronic pelvic pain or dysmenorrhea. It was initially misdiagnosed as an adnexal cyst in the right region based on ultrasound imaging, and laparoscopic exploration revealed a mass in the uterine corpus, leading to a revised diagnosis of accessory cavitated uterine malformation, which was confirmed through intraoperative findings and histopathological examination. The postoperative outcomes were favorable. This case underscores the diagnostic challenges of accessory cavitated uterine malformation, given the limited research on its pathogenesis and the absence of distinctive diagnostic markers. Imaging and histopathology are essential for an accurate diagnosis. Surgical intervention, especially laparoscopy, remains the preferred treatment, with excision typically resulting in a favorable postoperative prognosis.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 9","pages":"3000605251372459"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12417653/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145023467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between occupational dust exposure and asthma prevalence in a nationally representative US population.","authors":"Yi Dai, Yonghuai Li","doi":"10.1177/03000605251371280","DOIUrl":"https://doi.org/10.1177/03000605251371280","url":null,"abstract":"<p><p>ObjectiveThis study sought to examine the relationship between exposure to different types of workplace dust (mineral dust, organic dust, exhaust fumes, and other fumes) and the prevalence of asthma in a nationally representative sample of the population in the United States.MethodsUsing data from the National Health and Nutrition Examination Survey 2007-2012, we analyzed data of 16,841 participants after exclusions based on specific criteria. Logistic regression models were used to evaluate the association between dust exposure and asthma prevalence after adjusting for demographic and health-related covariates.ResultsOur findings indicate that exposure to various types of dust is positively associated with the prevalence of asthma. This association remained significant after adjusting for age, sex, race, and other covariates. Notably, subgroup analysis revealed that females are more susceptible to asthma from dust exposure than males. In addition, individuals with higher body mass index and older age are more likely to have asthma due to dust inhalation.ConclusionThis study underscores the need for targeted occupational health interventions and policies, especially for high-risk groups such as females, those with higher body weight, and older individuals. Further longitudinal studies are recommended to establish causal relationships.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 9","pages":"3000605251371280"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A prospective case-control study: Analysis of the analgesic effect of acetaminophen-mannitol injection after endoscopic lumbar discectomy.","authors":"Jie-Bin Huang, Yin-Feng Guo, Cheng-Zhao Li, Wei-Xiong Chen, Bai-Yong Zhu, Yu Lei, Wei-Dong Jiao, Li-Bin Zheng, Hou-Jun Xue","doi":"10.1177/03000605251372518","DOIUrl":"10.1177/03000605251372518","url":null,"abstract":"<p><p>ObjectiveTo investigate the analgesic effects of acetaminophen-mannitol injections after endoscopic lumbar discectomy.MethodsThis is a prospective case-control study involving 60 patients who were randomly selected from those who underwent endoscopic lumbar discectomy for lumbar disc herniation or lumbar spinal stenosis at Sanshui District People's Hospital of Foshan between April and September 2024. Two groups were formed by randomly assigning patients, with each group containing 30 individuals. The observation group underwent treatment with acetaminophen-mannitol for pain relief, whereas the control group was administered oral etoricoxib and intravenous mannitol. A comparison was made between the analgesic effects of the two groups.ResultsCompared with the control group, the observation group showed significantly lower visual analog scale scores on the first, third, and seventh days after operation (<i>P</i> < 0.05). The observation group had a similar time to start walking and length of hospital stay as the control group. The total incidence rate of adverse reactions was zero.ConclusionAcetaminophen-mannitol injection has a good analgesic effect after endoscopic lumbar discectomy, which is beneficial for accelerating the postoperative recovery of patients.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 9","pages":"3000605251372518"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12413524/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145006294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of dapagliflozin on proteinuria and the slope of the estimated glomerular filtration rate in patients with immunoglobulin A nephropathy: A multicenter prospective study.","authors":"Takeo Koshida, Hitoshi Suzuki, Maki Murkoashi, Hisatsugu Takahara, Yusuke Suzuki, Tomohito Gohda","doi":"10.1177/03000605251376895","DOIUrl":"10.1177/03000605251376895","url":null,"abstract":"<p><p>ObjectiveThe sodium-glucose cotransporter-2 inhibitor dapagliflozin reduces proteinuria and slows the decline in estimated glomerular filtration rate in patients with chronic kidney disease. Dapagliflozin is reported to be effective in patients with immunoglobulin A nephropathy; however, there have been only a few real-world clinical trials involving patients with immunoglobulin A nephropathy. Therefore, we aimed to evaluate the effect of dapagliflozin in Japanese patients with immunoglobulin A nephropathy.MethodWe performed a multicenter, nonblinded, single-arm, prospective observational study involving 44 patients with immunoglobulin A nephropathy. Patients who had completed corticosteroid treatment and were currently undergoing renin-angiotensin system inhibitor therapy were primarily enrolled.ResultsAt baseline, the mean estimated glomerular filtration rate was 56.2 ± 29.4 mL/min/1.73 m², and the median urinary protein-to-creatinine ratio was 0.63 g/g (interquartile range: 0.32-1.22 g/g). The estimated glomerular filtration rate decreased significantly after 1 month and plateaued thereafter. The urinary protein-to-creatinine ratio significantly decreased in patients with higher proteinuria (>0.5 g/g), but not in those with less proteinuria (<0.5 g/g). The post-treatment estimated glomerular filtration rate slope was significantly attenuated compared with the pretreatment slope, especially in patients with a relatively rapid decline in estimated glomerular filtration rate.ConclusionDapagliflozin reduces residual proteinuria, even after treatment with corticosteroids and renin-angiotensin system inhibitors, in patients with biopsy-confirmed immunoglobulin A nephropathy. These findings may guide future treatment strategies for immunoglobulin A nephropathy.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 9","pages":"3000605251376895"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12446846/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145086128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emerging evidence on transcatheter edge-to-edge repair for secondary mitral regurgitation.","authors":"Francesco Nappi","doi":"10.1177/03000605251378694","DOIUrl":"10.1177/03000605251378694","url":null,"abstract":"<p><p>The surgical management of mitral valve disease is undergoing rapid development, with various treatment options available. Increasing evidence has emerged on the optimal strategy for the management of secondary mitral regurgitation, a condition characterised by ventricular pathology. This review discusses surgical treatments for secondary mitral regurgitation. Currently, there is no consensus on the optimal strategy for the treatment of patients with secondary mitral regurgitation. Management of this condition requires a dedicated heart team to ensure the most favourable outcome by tailoring interventions to individual patients. The aim of this narrative review is to compare available interventions for secondary mitral regurgitation.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 9","pages":"3000605251378694"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12464391/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145149303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative outcomes and success rates of regenerative endodontics versus traditional root canal therapy: A systematic review and meta-analysis.","authors":"Asiya Mujawar, Varsha Pandit, Sumaiyya Shaikh, Bilal Shaikh, Noura A Alessa, Mohammed Abdul Kader, Mohammed Alqarni, Mohmed Isaqali Karobari","doi":"10.1177/03000605251379243","DOIUrl":"10.1177/03000605251379243","url":null,"abstract":"<p><p>ObjectiveThis systematic review and meta-analysis aimed to evaluate the efficacy of regenerative endodontic procedures compared with conventional root canal treatment procedures in mature permanent teeth with periapical lesions.MethodsThis systematic review and meta-analysis were conducted following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Randomized controlled trials that were included in the study compared regenerative endodontic procedures with traditional root canal treatment procedures in mature permanent teeth with irreversible pulpitis. The Risk of Bias 2 tool was used for quality assessment, and the certainty of the evidence was evaluated using the GRADE approach. Meta-analysis was performed using the RevMan Web software, using odds ratios for dichotomous outcomes and mean differences for continuous outcomes, with a random-effects model applied. Heterogeneity was assessed using the I² statistic, and publication bias was evaluated using funnel plots and Egger's test.ResultsThe analysis included five studies encompassing diverse regenerative strategies. Overall, regenerative endodontic procedures demonstrated comparable or superior clinical and radiographic healing outcomes relative to conventional treatments. Notably, certain regenerative approaches showed greater potential for restoring pulp vitality and reducing early postoperative pain. However, the quality of evidence was moderate, constrained by small sample sizes, methodological heterogeneity, and blinding challenges.ConclusionCurrent evidence suggests that regenerative endodontic procedures are promising alternatives to conventional root canal treatment procedures for mature teeth with periapical lesions. Despite these encouraging findings, further high-quality, multicenter trials with standardized protocols and extended follow-up periods are necessary to confirm the results and establish the long-term benefits and cost-effectiveness of regenerative endodontics.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 9","pages":"3000605251379243"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12475698/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145176079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postoperative delirium after short-acting spinal anesthesia and general anesthesia after shared decision-making.","authors":"Valesca Kipping, Timo B Kerlin, Friedrich Borchers, Margret F Külken, Marilena Schmid, Christopher S Ahrend, Janine Wiebach, Sophie K Piper, Klaus D Wernecke, Anika Müller, Claudia D Spies","doi":"10.1177/03000605251363408","DOIUrl":"10.1177/03000605251363408","url":null,"abstract":"<p><p>ObjectivePrevious studies have shown that the postoperative delirium rate does not differ between anesthetic techniques in randomized controlled trials. Subjective concerns such as anxiety and pain are often not adequately addressed in randomized controlled trials and reported to be associated with postoperative delirium. Shared decision-making is reported to have an impact on anxiety and pain. Therefore, the aim of this study was to evaluate the effect of shared decision-making while making a choice between spinal and general anesthesia on postoperative delirium incidence.MethodsThis prospective, observational, two-armed cohort study included 192 patients who underwent lower extremity, lower abdominal, pelvic, or perineal short-time surgery that lasted <90 min. The three-talk shared decision-making model was used to make the choice for the type of anesthesia. Depending on the shared decision-making process, either spinal anesthesia with short-acting local anesthetics (prilocaine hydrochloride or chloroprocaine hydrochloride) or general anesthesia was performed according to a standardized protocol including intraoperative electroencephalogram monitoring. Patients' anxiety and pain levels were measured before and after the surgery using validated scales.ResultsBased on their shared decision-making choice of anesthesia, 97 patients were allocated to the spinal anesthesia group and 95 to the general anesthesia group. Postoperative delirium occurred less frequently after spinal anesthesia (2.1%) than after general anesthesia (16.8%; p < 0.001). No postoperative delirium was observed in patients who received only spinal anesthesia, as chosen using the shared decision-making model (spinal anesthesia: 0%, general anesthesia 16.8%; p < 0.001). Anxiety and pain levels did not differ between the two groups.ConclusionsThe incidence of postoperative delirium was lower in patients who were administered spinal anesthesia than in those who were administered general anesthesia after using a shared decision-making approach. Integrating patients' perspectives and treatment preferences might change postoperative outcomes and should be taken into consideration in future trials.<b>Trial registration:</b> clinicaltrials.gov: NCT03715244https://clinicaltrials.gov/study/NCT03715244?intr=NCT03715244&rank=1.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 9","pages":"3000605251363408"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12433544/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145058515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative coagulation parameters predict postoperative bleeding after endovascular treatment of intracranial aneurysms: A retrospective cohort study.","authors":"Zhengjun Wu, Hong Liu, Mingfang He","doi":"10.1177/03000605251379524","DOIUrl":"10.1177/03000605251379524","url":null,"abstract":"<p><p>ObjectiveTo develop a simple preoperative prediction model for postoperative bleeding in patients undergoing endovascular treatment for cerebral aneurysms.MethodsIn this retrospective cohort study, we analyzed 209 patients who underwent endovascular embolization at a single center. Patients were categorized into bleeding and nonbleeding groups. Clinical characteristics and laboratory parameters were compared. Logistic regression identified independent predictors, and model performance was assessed using receiver operating characteristic analysis and bleeding risk stratification.ResultsPatients in the bleeding group had significantly higher prothrombin time, international normalized ratio, and lower fibrinogen levels (all <i>P</i> < 0.001). Multivariate analysis identified prothrombin time (odds ratio: 1.46), international normalized ratio:  > 1.1 (odds ratio: 5.40), and fibrinogen levels (odds ratio: 0.081) as independent predictors. The model showed good discrimination (area under the receiver operating characteristic curve = 0.873). Bleeding incidence was significantly higher in the high-risk group (61.3%) than in the low-risk group (9.5%) (<i>P</i> < 0.001).ConclusionsA simple model based on prothrombin time, international normalized ratio, and fibrinogen levels can effectively predict bleeding risk after aneurysm embolization, aiding in individualized perioperative management. The relatively high bleeding rate observed may reflect the inclusion of minor, asymptomatic hemorrhages based on predefined imaging criteria and highlights the importance of sensitive perioperative coagulation monitoring, particularly in heterogeneous clinical contexts such as subarachnoid hemorrhage.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 9","pages":"3000605251379524"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12461063/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case report of retroperitoneal leiomyosarcoma originating from the right ovarian vein and invading the right renal vein and inferior vena cava.","authors":"Chengbin Lu, Leyu Zhang, Benmo Xu, Tianyu Li, Die Fan, Changyang Li, Yuanlong Shi, Xin Li, Bin Zhao","doi":"10.1177/03000605251364059","DOIUrl":"10.1177/03000605251364059","url":null,"abstract":"<p><p>A woman in her early 50s was admitted to our hospital with a right retroperitoneal tumor that had been detected >1 year ago. Imaging studies revealed a mass in the right middle and lower retroperitoneum, which involved the upper portion of the right fallopian tube and caused dilated hydronephrosis of the right renal pelvis and calyces. Initial diagnosis suggested benign intraventricular smooth muscle neoplasia. She underwent surgical resection of the right retroperitoneal tumor, along with thrombectomy of the right renal vein and inferior vena cava, as well as artificial revascularization of the right renal vein. Postoperative pathology confirmed retroperitoneal smooth muscle sarcoma. She received postoperative chemotherapy with ifosfamide and doxorubicin as well as anticoagulation therapy with rivaroxaban. One year later, follow-up imaging revealed multiple nodules in the right middle and lower abdomen, a blurred nodule in the tail of the pancreas, and a dilated pancreatic duct in the distal pancreas, raising suspicion of metastasis.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 8","pages":"3000605251364059"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12344342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144821589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}