The Internet Journal of Dermatology最新文献

{"title":"Glomus Tumor of the Cheek","authors":"Bo Wang, Jeff F. Wang, J. Shehan, D. Sarma","doi":"10.5580/206d","DOIUrl":"https://doi.org/10.5580/206d","url":null,"abstract":"We are reporting two cases of glomus tumor of the cheek that we had recently encountered during the last six months. English literature is briefly reviewed. CASE REPORTS A 51-year-old male presented with an asymptomatic red right lower cheek lesion that was clinically diagnosed as a “venous lake”. An excisional biopsy was performed and showed a glomus tumor (Figures A1, A2, and A3). Figure 1 Figure A1: Right check glomus tumor in a 51-year-old male Figure 2 Figure A2: Microscopic appearance Figure 3 Figure A3: Higher magnification The second case was that of a 58-year-old female with a left Glomus Tumor of the Cheek 2 of 4 check lesion that was clinically thought to be “epidermal cyst”. An excisional biopsy revealed the typical features of a glomus tumor (Figures B1, B2 and B3). Figure 4 Figure B1: Left check glomus tumor in a 58-year-old female Figure 5 Figure B2: Microscopic appearance Figure 6 Figure B3: Higher magnification Microscopically both tumors showed prominent vascular spaces rimmed by a variable thickness of glomus cells (Figure 2) with dark small uniform nuclei and slightly eosinophilic cytoplasm (Figure 3). There was no mitotic activity or necrosis. COMMENT Glomus tumor is a rare benign painful tumor commonly found in the corium and subcutaneous tissue, mostly in the subungual region of the fingers. It arises from the rests of glomus bodies, which are specialized structures at arteriovenous anastomosis functioning in thermal regulation. Extradigital glomus tumor is a rare entity, especially in the location, such as cheek. In a reported study of 56 extradigital glomus tumors seen in Mayo Clinic over a period of twenty years (1985-2005), the authors found a single case occurring in the cheek [1]. Other reported sites for extradigital glomus tumors include face [2], colon [3], stomach, lung, bone, nervous system, and fallopian tubes [1]. Extradigital glomus tumors can be a diagnostic challenge for the clinicians. The characteristic symptoms of digital glomus tumors, e.g., pain, pinpoint tenderness with blunt palpation, and hypersensitivity to cold, may not be present. Excisional biopsy is usually necessary for the diagnosis as well as the treatment CORRESPONDENCE TO Deba P. Sarma, M.D. Department of Pathology Creighton University Medical School Omaha, NE 68131 debasarma@creighton.edu Glomus Tumor of the Cheek 3 of 4 References 1. Schiefer TK, Parker WL, Anakwenze OA, Amadio PC, Inwards CY, Spinner RJ. Extradigital glomus tumors: a 20- year experience. Mayo Clin Proc. 2006 Oct;81(10):1337-44. 2. Mounayer C, Wassef M, Enjolras O, Boukobza M, Mulliken JB. Facial \"glomangiomas\": large facial venous malformations with glomus cells. J Am Acad Dermatol. 2001 Aug; 45(2):239-45. 3. Oliphant R, Gardiner S, Reid R, McPeake J, Porteous C. Glomus tumour of the ascending colon. J Clin Pathol. 2007 Jul; 60(7):846. Glomus Tumor of the Cheek 4 of 4 Author Information Bo Wang, M.D. Assistant Professor of Pathology, Creighton University Medical Center J","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115131217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mucocutaneous Adverse Drug Reactions In A Hospital Setting In Cameroon","authors":"J. Mbuagbaw, L. Mbuagbaw, A. Chiabi, Cecile Bisseck, M. Nkam","doi":"10.5580/2538","DOIUrl":"https://doi.org/10.5580/2538","url":null,"abstract":"Mucocutaneous drug reactions are common in our setting. Our objectives were to evaluate the prevalence of mucocutaneous drug reactions due to systemic drugs. A retrospective cohort study of outpatients with the diagnosis of Adverse Drug Reaction was carried out over 6 years in the University Teaching Hospital, Yaoundé. 138 cases of mucocutaneous drug reactions were evaluated. Fixed Drug Eruptions accounted for more than 60.7% of all the Adverse Drug Reactions. Sulphonamides were responsible for 82% of all the Fixed Drug Eruptions and were the offending drug in 65% of all the Adverse Drug Reactions documented. 28.9% of the subjects were HIV positive. 24 cases were hospitalized because of severity out of which 6 died (25%).The prevalence of drug reactions in the study is 3.5 %. The most common drug reaction is the Fixed Drug Eruption. The most offending drugs are Sulphonamides. Proper management of Adverse Drug Reactions is necessary and early referral of patients may be life saving.","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132876671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of specific aeroallergen sensitivity on skin prick test in patients with allergic rhinitis in Westchester County","authors":"P. Basak, Ricardo B. Arayata, J. Brensilver","doi":"10.5580/1e9f","DOIUrl":"https://doi.org/10.5580/1e9f","url":null,"abstract":"Allergic rhinitis is the most common cause of rhinitis, and is often the diagnosis prompting referral to the allergist for skin prick tests (SPT). The prevalence of positive SPT to different aeroallergens varies with the geographic setting. Westchester County is located in the state of New York, and there are no local data to date reflecting the prevalence of positive SPT. We therefore undertook a study to determine the reactivity to aeroallergens in the local population. The results of SPT to 48 aeroallergens and 2 controls were analyzed in 100 patients referred for allergic rhinitis. 65% had a positive SPT to at least 1 aeroallergen. Amongst the molds, alternaria positivity was noted in 8%, cat hair reacted in 18%, birch antigen was positive in 20% and reactivity to grass mix antigen was observed in 24%. The antigen showing the greatest SPT positivity was the house dust mite (30%). Sensitization rates for other antigens are presented.","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123648671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary Cutaneous Coccidioidomycosis: Clinical Case Report and Discussion","authors":"U. Malik, S. Kapre, J. Saffier","doi":"10.5580/1aa6","DOIUrl":"https://doi.org/10.5580/1aa6","url":null,"abstract":"Coccidiomycosis is a rare fungal infection which usually affects only the lungs. Involvement of the skin by the causative fungus is very rare. Depending on the organ of primary infection, cutaneous involvement can be sub grouped into two types a) primary and b) secondary. Primary cutaneous infection is extremely rare and usually occurs when Coccidioides inoculates traumatized skin. In this article we report a case of the primary cutaneous coccidiomycosis of the nose. To our knowledge this is only second reported case of the primary infection of the skin of the nose by Coccidioides and first reported case of primary cutaneous coccidiomycosis of the nasal alae. (1)","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121639330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of MITF (Microphthalmia-Associated Transcription Factor) Immunostain for Diagnosis of Desmoplasic Melanoma","authors":"Jeff F. Wang, Bo Wang, J. Shehan, D. Sarma","doi":"10.5580/24a0","DOIUrl":"https://doi.org/10.5580/24a0","url":null,"abstract":"We are reporting a case of desmoplastic malignant melanoma that was confirmed by immunostaining for microphthalmiaassociated transcription factor (MITF). A brief review of utility of MITF for diagnosis of melanoma is presented.","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"06 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127200500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Solid and Cystic Clear Cell Hidradenoma with Focal Intracystic Carcinoma in-Situ","authors":"Bo Wang, D. Sarma, B. Javadzadeh, J. Shehan","doi":"10.5580/241d","DOIUrl":"https://doi.org/10.5580/241d","url":null,"abstract":"A rare case of a nodulocystic hidradenoma with intracystic carcinoma in-situ occurring in the scalp of a 79-year-old man is reported.","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125794286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Giant Sebaceous Cysts of scalp: A Case Report","authors":"I. Wani, B. Bhat, I. Mir, Tahir Saleem, M. Rather, Misbah Afsheen, S. QadrI, Idrees Bashir, S. Mushtaq, M. Nazir","doi":"10.5580/1f20","DOIUrl":"https://doi.org/10.5580/1f20","url":null,"abstract":"The authors are reporting a rare case of giant sebaceous cysts on scalp. A neglect of patient resulting in enormous size of cyst. Local excision is modality of treatment. INTRODUCTION Several dermatosis are encountered in day to day surgical practice. The pathology vary from benign to malignant one, but very often benign cutaneous lesions are encountered.A sebaceous cyst of scalp is uncommon entity. Neglect on the part of patient sometimes leads to giant sebaceous cyst formation rarely encountered. These giant sebaceous cysts are more prone for developing malignancy CASE PRESENTATION A 60 year old male presented with two painless swellings on scalp of 15 years duration. Both of the swellings increased progressively in size and there was no positive history of trauma or infection. General and systemic examination was within normal limits. Local examination of two swellings revealed larger one 7.3× 6.9×2.4 cm, second one being 6.1×5×2 cm,in dimensions, nontender ,fixed to underlying skin but freely mobilefrom underlying structures(Fig.1) Figure 1 Figure showing two large sebaceous cysts on scalp No neck lymphadenopathy was present, Excision of these giant sebaceous cysts was done.Histopathological examination was consistent with epidermoid cysts DISCUSSION Giant sebaceous cysts are rare entity in clinical practice1 Sebaceous cysts are presently called as epidermoid cysts .These asymptomatic, dome-shaped lesions are painless smooth skin lump with thick yellowy sebum in the lump . Cysts usually vary in size from 1cm to 4cm in diameter. Most of times often arise from a ruptured pilosebaceous Giant Sebaceous Cysts of scalp: A Case Report 2 of 3 follicle. Multiple epidermoid cysts are associated with lipomas or fibromas of the skin and osteomas and should be considered as part of Gardner's syndrome, with associated premalignant colonic polyps. Pathologically, epidermoid cysts are lined by a cornified epithelium with a distinct granular layer. It contains a lamellated keratin without calcificication . Some cysts can be associated with basal cell and squamous cell carcinoma.In long standing cases in elderly ,squamous cell carcinoma arises from this type of cyst . Bowen disease, metastatic carcinoma, Merkel cell carcinoma, and mycosis fungoides have all been reported in association with epidermoid cyst.Differential diagnosis includes milia,Pilar cysts nevoid basal cell carcinoma syndrome ,pachynychia congenital,lipomas , dermoid cyst.Treatment is excision of cyst. CORRESPONDENCE TO Imtiaz Wani Post Graduate Scholar Shodi Gali ,Amira Kadal , Srinagar , Kashmir,India 190009 Email: imtazwani@yahoo.com Cell.No.9419904864 References 1. Kim HS, Park HJ, Lee JY, Cho BK.A Case of Giant Sebaceous Hyperplasia on the Scalp of a Young Adult.. Korean J Dermatol. 2005;43(8):1124-1126. Korean. 2. A. Sagi, J. Goldstein, B. Greber, L. Rosenberg ,P. Ben- MeirSquamous cell carcinoma arising in sebaceous cyst .Case Reports .European Journal of Plastic SurgeryVolume 1988:11( 2","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115716550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minimizing the risk of adverse events with injectable poly-L-lactic acid","authors":"S. Weinkle","doi":"10.5580/a52","DOIUrl":"https://doi.org/10.5580/a52","url":null,"abstract":"Injectable poly-L-lactic acid (SculptraAE) is an effective and durable treatment for volume correction/restoration (in people with human immunodeficiency virus treatment-related facial fat loss [lipoatrophy]) and is well tolerated when administered correctly. Incorrect administration technique and suboptimal preparation of poly-L-lactic acid can lead to the formation of papules and nodules. In order to minimize the risk of development of these lesions, poly-L-lactic acid should be reconstituted correctly and injected subcutaneously at the junction of the dermis and subcutaneous fat using the appropriate technique tailored to both the patient and area of correction. Here we overview the best administration techniques for poly-L-lactic acid in order to minimize the potential for adverse effects and optimize treatment outcomes. Used correctly, poly-L-lactic acid is associated with a","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"24 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125929139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Skin Warts In Maiduguri, Nigeria: A Pathologic Review","authors":"A. A. Ndahi, G. Gadzama, H. Nggada","doi":"10.5580/249a","DOIUrl":"https://doi.org/10.5580/249a","url":null,"abstract":"Skin warts are common in our environment and accounted for 38.9% of all cases of biopsy skin lesions. The peak age is the 3rd decade of life and predominant in females giving a ratio of 1.7:1 over the males. The perineum and genital is the common site of skin warts (condyloma acuminatum) accounted for 41.9%. The lower limb accounted for 24 while the head and neck, and upper limb accounted for 11 cases each. One case was present on the trunk and 6 cases were unspecified. In conclusion, skin warts are not uncommon in our environment and therefore such lesions should be biopsied for histological diagnosis even when clinically suspected. This is because of the wide spectrum of differential diagnosis.","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125420629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermatomyofibroma: A Case Report And Review Of The Literature","authors":"Zenggang Pan, E. Adickes, D. Sarma","doi":"10.5580/5e1","DOIUrl":"https://doi.org/10.5580/5e1","url":null,"abstract":"Dermatomyofibroma is a rare, benign cutaneous tumor derived from myofibroblasts. It is predominantly found in young women, and only a few cases have been reported in males. This entity is not generally well known and often misdiagnosed. We report such a case of dermatofibroma occurring in a 23-year-old male with a brief review of the English literature.","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"223 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124441018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}