The Internet Journal of Dermatology最新文献

{"title":"The Prevalence Of Acne Vulgaris In Secondary School Students In Yaoundé, Cameroon","authors":"J. Mbuagbaw, Chenue Abongwa, G. Ozoh, K. N. Blackett","doi":"10.5580/2622","DOIUrl":"https://doi.org/10.5580/2622","url":null,"abstract":"Acne vulgaris is a common skin condition that leads to scaring and psychological morbidity. Our objectives where to define the prevalence and epidemiology of acne in secondary schools. Over 2 months, 585 adolescent students aged between 10 and 21 years where interviewed and examined. There were 319 (54.5%) girls and 265 (45.5%) boys aged 15.76±0.10. The prevalence of acne was 59.84%. Acne occurred just before puberty in both sexes. The prevalence was higher in those with a family history of acne. Most subjects had never sought medical advice. The distribution was mainly on the face (95%) followed by the back, shoulders and chest. There were negative feelings in the acne sufferers. The prevalence and morbidity of acne in Cameroon is similar to what is seen elsewhere. Education should highlight the problem and encourage adolescents to seek early medical advice. Early medical attention will improve cosmetic appearance and decrease psychosocial morbidity.","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116834343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bacterial Infection within a Rheumatoid Nodule: A Rarely Reported Finding","authors":"M. Murphy, Lauren Murphy, A. Berke, P. Kerr, J. Grant-Kels, R. Greenberg, D. Hoss","doi":"10.5580/1181","DOIUrl":"https://doi.org/10.5580/1181","url":null,"abstract":"We describe a palisaded granulomatous skin nodule containing bacterial rods, in a patient with rheumatoid arthritis (RA). The case emphasizes that fact that a known history of RA should not preclude submission of tissue for culture studies or careful histologic review for micro-organisms of any lesion that is interpreted as clinically and/or histologically consistent with a rheumatoid nodule. Cutaneous infection may be an etiological agent in the formation of rheumatoid nodules in a patient with known RA.","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124353695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Vitro Exposure To Cigarette Smoke Activates Eosinophils: Implications For Lung Inflammation","authors":"P. Hasgall, L. Bellehsen, I. Hammel, D. Amichai, F. Levi‐Schaffer","doi":"10.5580/24e6","DOIUrl":"https://doi.org/10.5580/24e6","url":null,"abstract":"Effects of cigarette smoke (CS) on eosinophils (EOS), important cells involved in the pathogenesis of chronic lung diseases such as asthma, were studied in vitro. EOS were isolated from healthy and mildly atopic donors and exposed to soluble components of cigarette smoke (CSE). Viability and apoptosis were assessed by flow cytometry after staining with propidium iodide and Annexin-V. Activation was determined by release of newly-synthesized (IL-8, IL-6) mediators and by phosphorylation of MAPKs. CSE effects on ultrastructural morphology and production of neutrophil chemotactic factors in CSE-activated EOS were also evaluated. CSE concentrations from 0-2.5% were non-toxic for up to 18-24 hours of exposure. However, CSE at 2.5% activated EOS as evidenced by ultrastructural degranulation: release of IL-8 and IL-6, and increased expression of the MAPK, c-Jun. Supernatants from CSE-activated EOS were found to be significantly chemotactic for neutrophils. These results suggest that CS may aggravate lung inflammation by activating EOS which, in turn, release inflammatory mediators promoting inflammatory cell recruitment and lung remodeling.","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"7 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131088751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inflammatory Pseudotumor of the Skin: A Case Report And Review Of The Literature","authors":"Jamie L Frey, C. Huerter, J. Shehan","doi":"10.5580/2706","DOIUrl":"https://doi.org/10.5580/2706","url":null,"abstract":"Inflammatory pseudotumor is a rare mesenchymal neoplasm most commonly developing in the viscera with very rare primary cutaneous involvement. This neoplasm, though usually behaving in a benign fashion, is actually considered to have intermediate biologic potential, as cases of local recurrence and death have been reported. We report the case of a 70-year-old male with a cutaneous inflammatory pseudotumor presenting on the thigh, which after biopsy and histologic identification, was completely excised. A review of this entity and other cases of inflammatory pseudotumor of the skin is presented.","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131899331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cutaneous Leiomyosarcoma of the Face","authors":"Eric E. Santos, D. Sarma","doi":"10.5580/48b","DOIUrl":"https://doi.org/10.5580/48b","url":null,"abstract":"We are reporting a case of cutaneous leiomyosarcoma occurring on the face of a 98-year-old woman with a brief review of the literature. SOURCE OF SUPPORT None REPORT OF A CASE A 98-year-old woman presented with a painful, nodular skin lesion localized to her left cheek. The skin surface was raised and dark brown to black. She reported no other associated symptoms and denied having other similar skin lesions. Her past medical history was otherwise unremarkable. On microscopic examination of the shave biopsy, the skin lesion showed a diffuse nodular proliferation of spindle cells with moderate cellular pleomorphism and an increased mitotic rate of up to 10 mitoses per high power field. The overlying epidermis was unremarkable (Figures 1 & 2). Figure 1 Figure 1: Cutaneous leiomyosarcoma, low magnification: Dermal proliferation of interlacing fascicles of spindle cells. Figure 2 Figure 2: Cutaneous leiomyosarcoma, high magnification. Multiple immunohistochemical stains were performed that showed positive tumor cell staining for vimentin and smooth muscle actin (Figure 3), and negative staining for S-100, CD34, and MelanA. The lesion was interpreted as a leiomyosarcoma. A complete excision was recommended. Cutaneous Leiomyosarcoma of the Face 2 of 3 Figure 3 Figure 3: Cutaneous leiomyosarcoma, Focal positive staining with SMA (smooth muscle actin). COMMENT Primary cutaneous leiomyosarcomas are rare neoplasms, either located in the dermis or subcutaneous tissue. More than 100 cases of dermal leiomyosarcomas have been reported [1], most occurring in patients usually around the sixth decade of life. Our patient probably represents one of the oldest patients with this lesion. Most of the lesions are located in the extremities. We could only uncover one report of dermal leiomyosarcoma occurring in the face [2]. Although the lesion was localized to the dermis in this case, skin leiomyosarcomas can also appear within the subcutis. Surgical excision is the treatment of choice. High rates of local recurrence for both cutaneous and subcutaneous lesions ranging from 50% to 70% have been previously reported. Histological factors that have been reported to predict recurrence rate include size of lesion, increased mitotic count, and tumor extension to the subcutis. CORRESPONDENCE TO Deba P. Sarma, MD Department of Pathology Creighton University Medical Center Omaha, NE 68131 Tel: 402-449-4951 E-mail: debasarma@creighton.edu References 1. Weedon, D. Skin Pathology. 2nd ed. Edinburgh: Churchill Livingston, 2002. 971. 2. Orellana-Diaz, O, and E Hernandez-Perez. \"Leiomyoma Cuis and Leiomyosarcoma: a 10-Year Study and a Short Review.\" Journal of Dermatology and Surgical Oncology 9 (1983): 283-287. Cutaneous Leiomyosarcoma of the Face 3 of 3 Author Information Eric E. Santos, M.D. Senior Resident, Department of Pathology, Creighton University Medical School Deba P. Sarma, M.D. Professor, Department of Pathology, Creighton University Medical School","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131913624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patch Testing In Cosmetic Dermatoses: A Report From South India","authors":"A. Nath, D. Thappa","doi":"10.5580/2e3","DOIUrl":"https://doi.org/10.5580/2e3","url":null,"abstract":"Thirty five patients with cosmetic dermatoses were patch tested in this study. Out of 35 patients, 23 were female and 12 were male, with a female to male ratio of 1.9:1. Mean age of patients was 42 years. Kumkum was the incriminated cosmetic in 24 patients, sticker bindi in 5 patients, kumkum and sticker bindi both in 1 patient, hair dye in 3 patients, Fair & Lovely and aftershave lotion in 1 patient each. Out of 2380 patches applied, positive reactions were seen in 57 patches. Twenty eight out of 35 patients had positive (allergic) patch test reaction. Thimerosal showed positive reaction in 27 patients (27/35), gallate mix in 15 patients (15/35), paraphenylenediamine in five patients (5/35), nickel sulphate in two patients, and parabens, Kathon CG, benzotriazol, tertiary-butyl hydroquinone, quaternium-15, balsam of Peru, potassium dichromate and cobalt chloride in one patient each.","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127373325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A brief review of the \"vulgaris\" lesions of the skin","authors":"Mingkui Chen, E. Bruno, Eric E. Santos, D. Sarma","doi":"10.5580/421","DOIUrl":"https://doi.org/10.5580/421","url":null,"abstract":"Medical students and the trainees in dermatology and pathology have a curiosity about the names, such as, acne vulgaris or verruca vulgaris. The word “vulgaris” sounds like vulgar, commonly meaning crudely indecent, coarse, or obscene. However, the word “vulgar” is derived from the Latin word “vulgaris”, meaning “of or belonging to the common people”. In medical terminology, the word “vulgaris” means common or ordinary. A search through the indexes in Dermatology and Pathology text books revealed seven dermatologic conditions with “vulgaris” in their names. These included very common diseases, such as, acne vulgaris and verruca vulgaris as well as now rarely diagnosed disease, such as, lupus vulgaris. We are briefly reviewing the seven “vulgaris” diseases of the skin.","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115885016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Skin Colonization With Staphylococcus Aureus In Patients With Atopic Dermatitis","authors":"Fakhr zaman Pezesk pour, S. Miri, R. Ghasemi, R. Farid, Javad Ghenaat","doi":"10.5580/e93","DOIUrl":"https://doi.org/10.5580/e93","url":null,"abstract":"Objectives: To investigate the presence of S. aureus in the skin of AD patients and compare with healthy control group. Patients/Methods: Forty patients with AD were recruited in to our study. S. aureus skin colonization was determined in AD patients and controls, also skin distribution of S. aureus colonization was compared in three age groups of AD patients. Results: S. aureus was found on the skin of 42.5% and 7.5% of AD patients and control group, respectively (p=0.0003). The most common involved skin areas with S. aureus colonization were face (in ≤2 yrs old), flexor surfaces (in >2 and ≤12 yrs old) and extremities (in >12 yrs old). Conclusions: The incidence of S. aureus on the skin of AD patients was considerably higher rather than controls. Further studies are needed to investigate the clearance of S. aureus from the skin of AD patients using anti-staphylococcal treatment. The work was done at Department of Dermatology and Microbiology of Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114795905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neurofibromatosis Type 1 associated with vitiligo and left occipital bone defect","authors":"I. Bukhari, F. A. Mulhim","doi":"10.5580/474","DOIUrl":"https://doi.org/10.5580/474","url":null,"abstract":"Neurofibromatosis type 1 (NF1) is a neurocutaneous disorder with variable clinical expression spectrum. Major clinical features include pigmentary changes, central nervous system tumors, bony dysplasias and ophthalmic features. In this report we document the first case in the literature of NF1 associated with vitiligo and unusual bony defect.","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123938172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Malignant Atrophic Papulosis","authors":"A. Agarwal, K. Shivaswamy, D. Thappa, S. Jayanthi","doi":"10.5580/233e","DOIUrl":"https://doi.org/10.5580/233e","url":null,"abstract":"A 21 –yearold male presented to our dermatology OPD with multiple asymptomatic raised skin lesions on the trunk, neck, arms and forearms of six months duration. The patient had been referred to us from Surgery department for evaluation. He had undergone an abdominal surgery (a month ago) for multiple ileal perforations for which an ileal resection was done. He had no other systemic complaints. There was no family history of similar illness.","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124675550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}