{"title":"Sinus Headache And Migraine Overlap In A Case Of A Sturge-Weber Syndrome","authors":"J. Gulia, S. Yadav, N. Malhotra, C. Dhull","doi":"10.5580/19b3","DOIUrl":"https://doi.org/10.5580/19b3","url":null,"abstract":"Sturge Weber Syndrome (SWS) is a congenital syndrome of unknown cause and is characterized by a triad of port-wine stain, glaucoma, and central nervous system involvement. Migraine is a known feature of SWS. Sinus headache and migraine symptoms can overlap resulting in difficulty in diagnosis and treatment. A case of SWS having overlap of migraine and sinus headache is presented and diagnostic and treatment modalities are discussed.","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122666155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Lee-Wong, M. Karagic, S. Gomez, Anwar C Wilson, D. Resnick
{"title":"Adding Osteopathic Intervention to Albuterol Nebulization in Ambulatory Asthma Exacerbations","authors":"M. Lee-Wong, M. Karagic, S. Gomez, Anwar C Wilson, D. Resnick","doi":"10.5580/2527","DOIUrl":"https://doi.org/10.5580/2527","url":null,"abstract":"Background: Asthma is a chronic obstructive airway disease affecting children and adults world wide. Patients often seek alternative therapies.Objective: We conducted this study to describe osteopathic manipulative treatment (OMT) as an adjunct to traditional therapies in acute asthma exacerbation.Methods: A sample of previously diagnosed asthma patients who were having an acute asthma exacerbation were offered to receive OMT treatment as an adjunct to traditional modalities of treatment for acute exacerbation. Each patient was given an albuterol nebulizer treatment followed by an accepted OMT technique known as “rib raising” maneuver for five minutes. Peak flows were obtained before and after each treatment. Each patient was asked to fill out a symptom score diary rating their asthma symptoms before nebulizer treatment, after nebulizer treatment and after OMT.Results: The data showed an average increase in peak flow rates after nebulizer treatment was 36 L/min with a further average increase in peak flow after OMT of 18 L/min with a net increase of 54 L/min (ANOVA, p<0.05). OMT was not associated with any adverse effects or complaints. Study patients reported that the combined nebulizer and OMT treatments made them feel better than in the past when they were offered only traditional albuterol nebulizer treatments. Conclusion: Patients treated for acute asthma exacerbation with nebulizer treatment followed by osteopathic treatment (rib raising maneuver) showed significant improvement in their overall breathing. Unfortunately, lack of a control group in which there would be nebulizer treatment plus no osteopathic treatment makes it uncertain whether this OMT treatment had more than a placebo effect. However, since more patients request alternative therapies more research in OMT techniques should be considered. Offering osteopathic treatments as adjunct to traditional asthma treatment in an acute setting appears to have no adverse effects and may have psychological benefits.","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121584030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case of Adult T-cell Leukemia Masquerading as Mycosis Fungoides","authors":"L. Pinter-Brown","doi":"10.5580/1371","DOIUrl":"https://doi.org/10.5580/1371","url":null,"abstract":"INTRODUCTION AND INITIAL PRESENTATION This 81 year old Japanese American male presented 9 years ago with a rash that was diagnosed as psoriasis and was treated with 14 weeks of light therapy. Shortly after this therapy a skin biopsy of the right buttock revealed an atypical T-cell infiltrate consistent with mycosis fungoides with the malignant cells positive for CD 2,3,4, and 5 but negative for CD7 and 8. The epidermis showed hyperkeratosis, hyperparakeratosis, and acanthosis and there was a band-like lymphocytic infiltrate in the superficial dermis. Epidermotropism and Pautrier microabscesses with atypical lymphocytes with convoluted nuclei and occasional large cells were noted. T-cell gene rearrangement and HTLV-1 serology were positive. Bone marrow examination was unrevealing. While the patient had not ever been in Japan, his father came from Kyushu. The patient received therapy with PUVA with an initial response, then experienced progression in skin. Treatment with topical BCNU and extracorporeal photopheresis were also rendered; again with initial short-lived responses, then progression of the skin rash. Two years after the initial diagnostic skin biopsy, the patient had a PET scan showing right hilar, axillary, and inguinal adenopathy. The patient began therapy with bexarotene with a complete response in skin and continued on bexarotene in good health for 3 years. He then presented with a hemoglobin of 8.9 and white blood cells of 12,800. CT scanning showed bilateral perihilar alveolar infiltrates, a 1.5 cm density at the right apex of the lung, mediastinal and right hilar adenopathy and splenomegaly with peripheral hypodensities.","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132407105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Long term Complete Response to Denileukin Diftitox and Bexarotene","authors":"M. Duvic, R. Talpur","doi":"10.5580/164a","DOIUrl":"https://doi.org/10.5580/164a","url":null,"abstract":"Madeleine Duvic, MD, is Professor of Internal Medicine and Dermatology, and Deputy Chairman of the Department of Dermatology at The University of Texas, M. D. Anderson Cancer Center in Houston, Texas. She is a founding member of the United States Cutaneous Lymphoma Consortium (USCLC), a Board member of the International Society for Cutaneous Lymphoma, and also serves as Director of The Cutaneous Lymphoma Clinic at MD Anderson Cancer Center. Dr. Duvic has also served on the Board of Directors of the American Academy of Dermatology (AAD). She is certified in Internal Medicine and Dermatology. She has been a principal and co-principal investigator on numerous clinical trials studying the immunology of T-cell mediated disorders and skin cancers, as well as clinical drug development and translational research in T-cell lymphomas, melanoma, and various skin cancers. A prolific author, she has written manuscripts, book chapters, abstracts, and over 300 peer-reviewed journal articles. She is co-author of a recent book on Retinoids and Carotenoids in Dermatology.","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130906308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Common Spindle Cell Malignant Neoplasms of the Skin: Differential Diagnosis and Review of the Literature","authors":"S. Repertinger, B. Teruya, D. Sarma","doi":"10.5580/2211","DOIUrl":"https://doi.org/10.5580/2211","url":null,"abstract":"Malignant and borderline-malignant neoplasms of the dermis can pose diagnostic challenges. Because these tumors can share similar clinical and histologic features, including a predominantly spindle cell morphology, the pathologist must be familiar with these entities in order to facilitate accurate diagnosis, as treatment for these tumors may be different. We review several of these lesions with respect to clinical and histologic features: desmoplastic melanoma, spindle cell carcinoma, spindle cell atypical fibroxanthoma, dermatofibrosarcoma protuberans, and cutaneous leiomyosarcoma.","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133120225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Folliculotropic Mycosis Fungoides: Response to Bexarotene","authors":"R. Talpur, M. Duvic","doi":"10.5580/ac1","DOIUrl":"https://doi.org/10.5580/ac1","url":null,"abstract":"Folliculotropic mycosis fungoides (FMF) is a variant of mycosis fungoides characterized by the presence of folliculotropic infiltrates, often with sparing of the epidermis, and preferential involvement of the head and neck. We report a man who was initially diagnosed with eosinophilic folliculitis but had classical FMF with ulceration and improved on bexarotene.","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"199 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126891238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Primary Cutaneous Anaplastic Large Cell Lymphoma - Long-term Management with Low Dose Methotrexate","authors":"S. Parker","doi":"10.5580/24de","DOIUrl":"https://doi.org/10.5580/24de","url":null,"abstract":"Dr. Parker is an Associate Clinical Professor of Dermatology at Emory University, Atlanta, Georgia and Chief of Dermatology at Emory’s affiliate, Grady Memorial Hospital. She is board certified in 1) dermatology and 2) clinical and laboratory dermatological immunology. Her clinical expertise is in cutaneous lymphoma as well as HIV-related dermatological disease.","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130670639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Peak Flow Meter Characteristics and Asthma.","authors":"G. Pesola, Lily Otolorin","doi":"10.5580/dda","DOIUrl":"https://doi.org/10.5580/dda","url":null,"abstract":"Asthma is an episodic disease characterized by acute airway narrowing in at least two common scenarios. The first is when an irritant such as cigarette smoke, fumes from an industrial source, strong perfume, or even exercise cause an acute bronchospastic event. This type of asthma usually reverses with bronchodilator therapy in the first 2 hours with little subsequent airway inflammation and recovery of peak flows back to the normal range. The only other treatment may be avoidance of the irritant if possible. In a second type of clinical situation, an asthmatic develops ongoing airway inflammation due to daily pollen exposure, chronic cockroach exposure in the household, or other chronic condition causing airway irritation resulting in progressive inflammation and eventual bronchospasm poorly relieved by bronchodilators alone. These patients do not normalize peak flow immediately and require systemic steroids either as an inpatient or outpatient. Normalization of peak flow may occur in 3-4 days or may take up to several weeks of systemic steroids. In both cases, monitoring of airway caliber is done with a peak flow meter.","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122534406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Repertinger, Eric E. Santos, Mingkui Chen, D. Sarma
{"title":"Intravascular Capillary Hemangioma of the Skin","authors":"S. Repertinger, Eric E. Santos, Mingkui Chen, D. Sarma","doi":"10.5580/f85","DOIUrl":"https://doi.org/10.5580/f85","url":null,"abstract":"Capillary hemangiomas are very common benign vascular neoplasms which frequently occur in the skin and intraoral mucous membranes. The intravascular variant of this lesion, however, is distinctly uncommon and has been reported rarely in the English literature. Those reported cases describe this tumor as arising in veins in cutaneous and extracutaneous sites. Here we report two cases of intravascular capillary hemangioma arising in the skin.","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122649049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnostic value of Dsg1 ELISA for pemphigus foliaceus: an appraisal","authors":"V. Wiwanitkit","doi":"10.5580/1212","DOIUrl":"https://doi.org/10.5580/1212","url":null,"abstract":"Pemphigus foliaceus, a dermatological immune disorder, usually presents with cutaneous blistering. Of the several diagnostic tools, enzyme-linked immunosorbent assay (ELISA) against desmoglein (Dsg) 1 is widely used. The diagnostic value of Dsg1 ELISA test was previously studied by others and gave differences in diagnostic power. In addition, most reports focused on small sample sizes. Therefore, a systematic meta-analysis was conducted to assess the diagnostic property of this test. In this paper, the author summarized the diagnostic value of Dsg1 ELISA for pemphigus foliaceus. In the literature, there are 4 published papers [1 – 4] on 232 cases and 446 controls (Table 1). The overall sensitivity and specificity are equal to 95.3 and 96.4 respectively. This supports the diagnostic usefulness of Dsg1 ELISA for diagnosing pemphigus foliaceus. Figure 1 Table 1. Reports on diagnostic value of Dsg1 ELISA for pemphigus folliculus","PeriodicalId":161194,"journal":{"name":"The Internet Journal of Dermatology","volume":"83 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115411579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}