Journal of Infection and Public Health最新文献

{"title":"Shifts in seasonal influenza patterns in Australia during and after COVID-19: A comprehensive analysis","authors":"Cynthia Lu ,&nbsp;Ian G. Barr ,&nbsp;Stephen Lambert ,&nbsp;Kerrie Mengersen ,&nbsp;Liping Wang ,&nbsp;Weizhong Yang ,&nbsp;Zhongjie Li ,&nbsp;Sotiris Vardoulakis ,&nbsp;Hilary Bambrick ,&nbsp;Wenbiao Hu","doi":"10.1016/j.jiph.2024.102620","DOIUrl":"10.1016/j.jiph.2024.102620","url":null,"abstract":"<div><h3>Background</h3><div>During the COVID-19 pandemic, seasonal influenza virus circulation was heavily suppressed worldwide. In Australia, since the virus re-emerged in 2022, shifts in seasonal influenza patterns have been observed. Both the 2022 and 2023 seasons started earlier than pre-pandemic norms and were categorised as moderate to severe, highlighting the renewed importance of prevention strategies for seasonal influenza.</div></div><div><h3>Methods</h3><div>We analysed influenza notification data from the Australian National Notifiable Diseases Surveillance System (<u>2012–2022</u>) and virological surveillance data from the FluNet database (<u>2012–2023</u>). Using generalised additive models, we compared predicted weekly influenza case counts during 2020–2022 with observed counts. Epidemic weeks were detected using a negative binomial threshold, and epidemic onset was estimated with a Bayesian Poisson count detection algorithm. Trends in epidemic magnitude and onset timing across influenza virus types and subtypes were compared for pre-, during, and post-COVID-19 periods.</div></div><div><h3>Results</h3><div>Seasonal influenza activity was nearly absent in 2020 and 2021 but rebounded significantly in 2022 and 2023. Epidemic detection confirmed suppressed seasonal influenza circulation during the pandemic. While influenza A subtypes returned to pre-pandemic onset timings in 2022, influenza B exhibited a significantly delayed onset. The 2022 and 2023 seasons were moderate to severe, with earlier-than-average season starts, underscoring the ongoing changes in influenza dynamics post-pandemic.</div></div><div><h3>Conclusions</h3><div>This study provided a detailed analysis of the disruptions and subsequent shifts in seasonal influenza patterns in Australia during and after the COVID-19 pandemic. The rapid resurgence of influenza activity in 2022 and 2023, combined with altered onset timings, highlights the importance of ongoing surveillance and adaptive forecasting models to address the evolving complexity of influenza epidemiology in the post-pandemic era.</div></div>","PeriodicalId":16087,"journal":{"name":"Journal of Infection and Public Health","volume":"18 1","pages":"Article 102620"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142872156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular investigation of Coxiella burnetii and Bartonella in heart valve specimens of patients with endocarditis in Iran","authors":"Mina Latifian ,&nbsp;Ehsan Mostafavi ,&nbsp;Mohammad Ali Broumand ,&nbsp;Fahimeh Bagheri Amiri ,&nbsp;Mohammad Reza Mohammadi ,&nbsp;Saber Esmaeili","doi":"10.1016/j.jiph.2024.102616","DOIUrl":"10.1016/j.jiph.2024.102616","url":null,"abstract":"<div><h3>Background</h3><div>Infective endocarditis (IE), is a medical condition that threatens human health. The aim of this study is the molecular investigation of <em>Coxiella burnetii</em> and <em>Bartonella</em> spp. in heart valves in Iran.</div></div><div><h3>Methods</h3><div>In this study, 146 patients with pathological evidence of IE and underwent heart valve surgery between 2016 and 2020 were selected. Furthermore, positive samples for <em>C. burnetii</em> were genotyped by the Multi Spacers Typing (MST) method, and positive samples for <em>Bartonella</em> were sequenced on the 16SrRNA gene.</div></div><div><h3>Results</h3><div>12 patients (8.2 %) were identified as positive cases of <em>C. burnetii</em>, and two novel genotypes of <em>C. burnetii</em> were identified using MST genotyping. Additionally, 15 patients (10.3 %) were diagnosed with <em>Bartonella</em> endocarditis, and all positive cases were identified as <em>Bartonella quintana</em>.</div></div><div><h3>Conclusion</h3><div>According to the identification of positive cases of Q fever endocarditis and <em>Bartonella</em> endocarditis, future studies in this field are suggested to focus on elucidating methods of prevention, diagnosis and treatment.</div></div>","PeriodicalId":16087,"journal":{"name":"Journal of Infection and Public Health","volume":"18 1","pages":"Article 102616"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Narrative review of factors associated with SARS-CoV-2 coinfection in Middle Eastern countries and the need to vaccinate against preventable diseases","authors":"Majid Alshamrani ,&nbsp;Fayssal Farahat ,&nbsp;Ali Albarrak ,&nbsp;Aiman El-Saed ,&nbsp;Atef M. Shibl ,&nbsp;Ziad A. Memish ,&nbsp;Mostafa Mousa ,&nbsp;Hammam Haridy ,&nbsp;Abdulhakeem Althaqafi","doi":"10.1016/j.jiph.2024.102600","DOIUrl":"10.1016/j.jiph.2024.102600","url":null,"abstract":"<div><div>This review evaluated the frequency of, and outcomes associated with, bacterial, fungal, and viral coinfection with SARS-CoV-2 in Middle Eastern countries via a PubMed search through February 2023. Ninety articles reported bacterial (n = 57), fungal (n = 32), and viral (n = 32) coinfections. High frequencies of coinfection with COVID-19 were identified, with rates and outcomes varying by setting, pathogen, surveillance/detection method, population characteristics, and drug-resistance status. Mortality rates were higher in patients with community-acquired (10.0 −42.9 %) and hospital-acquired (51.5 −66 %) bacterial coinfection versus those without (10.5 −21.7 %). Outcomes were worse with than without fungal coinfection, and fatality rates with mucormycosis coinfection reached 66.7 %. Outcomes with viral coinfection were highly variable; however, some data suggested a positive corelation between COVID-19 severity and influenza A and adenovirus coinfection. The negative outcomes associated with bacterial, fungal and some viral coinfections in individuals with COVID-19 support regular vaccination against vaccine-preventable diseases caused by these pathogens, especially among at-risk populations.</div></div>","PeriodicalId":16087,"journal":{"name":"Journal of Infection and Public Health","volume":"18 1","pages":"Article 102600"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142846678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of blaTEM, blaOXA, blaCTX-M, and blaSHV genes of antibiotic resistance in diarrheagenic E. coli causing enteric infection in hypertensive patients at Laquintinie Hospital, Littoral Region of Cameroon","authors":"Ornella Djiolieu Tsobeng,&nbsp;Armelle T. Mbaveng ,&nbsp;Michael F. Kengne,&nbsp;Ballue S.T. Dadjo,&nbsp;Delano G.T. Fonjou,&nbsp;Victor Kuete","doi":"10.1016/j.jiph.2024.102617","DOIUrl":"10.1016/j.jiph.2024.102617","url":null,"abstract":"<div><h3>Background</h3><div>Pathogenic <em>Escherichia coli</em> is one of the most common causes of acute watery diarrhea among children and adults in the developing world. The severity of infection by this bacterium is a product of many factors, including virulence properties and antimicrobial resistance. This study aimed to determine the distribution of different virulence genes of <em>E. coli</em> isolates in hypertensive and non-hypertensive patients and their association with some selected beta-lactam resistance genes.</div></div><div><h3>Methods</h3><div>At the Douala Laquintinie Hospital, 518 fecal samples were collected from both hypertensive and non-hypertensive patients with enteric infections. <em>E. coli</em> was isolated on eosin-methylene blue agar (EMB) and identified by the Api 20 E Galery. The virulence genes and extended-spectrum β-lactamase-producing (ESBL) <em>E. coli</em> genes were detected by simplex polymerase chain reaction (PCR), while antimicrobial susceptibility was tested by the Kirby-Bauer agar disc diffusion method.</div></div><div><h3>Results</h3><div>The prevalence of enteric infection due to diarrheagenic <em>E. coli</em> (n = 204) was found to be 39.38 % in the general population (n = 518). There were 55 enterovirulent <em>E. coli</em> isolates identified. According to hypertension (HTN), enteropathogenic <em>E. coli</em> (EPEC) isolates were more isolated in hypertensive patients (77.78 %) than in non-hypertensive patients (22.22 %), while enteroaggregative <em>E. coli</em> (EAEC) were the most frequent in non-hypertensive patients (58.33 %). EPEC, EAEC, enterotoxigenic <em>E. coli</em> (ETEC), and Shiga toxin-producing <em>E. coli</em> (STEC) isolates showed higher rates of resistance to amoxicillin (AMO) (90.48 %; 100.00 %; 100.00 %; 100.00 % vs 83.33 %; 85.71 %; 75.00 %; 50.00 %) and SXT (71.43 %; 80.00 %; 75.00 %; 75.00 % vs 0.00 %; 28.57 %; 50.00 %; 25.00 %) in hypertensive patients compared to non-hypertensive patients. The prevalence of ESBL-producing (ESBL-P) <em>E. coli</em> was 87.27 %. The resistance genes <em>bla</em>_TEM (64.71 % vs 52.38 %) and <em>bla</em>_OXA (23.53 % vs 9.52 %) were more frequently detected in hypertensive patients than in non-hypertensive patients. The high resistance to AMO was correlated with the presence of the <em>bla</em>_CTX-M gene (OR: 5.52; 95 % CI: 0.61–49.39; p = 0.093).</div></div><div><h3>Conclusion</h3><div>This study reveals the high burden of the typical EPEC, EAEC<em>,</em> and ESBL-P <em>E. coli</em> and confirmed the high occurrence of <em>bla</em>_CTX-M and <em>bla</em>_TEM among ESBL-producing <em>E</em>. <em>coli</em> in hypertensive patients. The study suggests that measures need to be taken to reduce the harmfulness of enterovirulent <em>E. coli</em> and the resistance of enterovirulent <em>E. coli</em> in hypertensive patients.</div></div>","PeriodicalId":16087,"journal":{"name":"Journal of Infection and Public Health","volume":"18 1","pages":"Article 102617"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CTLA-4 rs5742909 but not ADAM33 rs2280091 is a predictor factor for COVID-19 mortality","authors":"Farzaneh Sheikhian ,&nbsp;Mohammad Mehdi Golparvar ,&nbsp;Iraj Ahmadi ,&nbsp;Enayat Anvari ,&nbsp;Fatemeh Majdolashrafi ,&nbsp;Morteza Ghazanfari Jajin ,&nbsp;Fatemeh Sakhaee ,&nbsp;Mojgan Sheikhpour ,&nbsp;Abolfazl Fateh","doi":"10.1016/j.jiph.2024.102618","DOIUrl":"10.1016/j.jiph.2024.102618","url":null,"abstract":"<div><h3>Background</h3><div>Research has demonstrated the association between susceptibility to coronavirus disease 2019 (COVID-19) and single nucleotide polymorphisms (SNPs). On the other hand, the cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) serves as a pivotal inhibitory receptor with a substantial impact on the advancement of viral infections. Besides, the disintegrin and metalloproteinase33 (<em>ADAM33</em>) gene is associated with both asthma and heightened airway responsiveness. Hence, this investigation sought to elucidate the potential association between the <em>CTLA-4</em> rs5742909 and <em>ADAM33</em> rs2280091 SNPs and the fatality rate of COVID-19 across various variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).</div></div><div><h3>Methods</h3><div>Both SNPs were genotyped with the PCR-RFLP assay in 1734 improved and 1450 deceased individuals.</div></div><div><h3>Results</h3><div>Our obtained results revealed a significant association between the <em>CTLA-4</em> rs5742909 C/T-T/T genotypes and increased mortality risk of COVID-19 in three different SARS-CoV-2 variants. The <em>ADAM33</em> rs2280091 polymorphism demonstrated no significant association with COVID-19 mortality under various inheritance models. Nevertheless, subsequent adjustments for SARS-CoV-2 variants revealed a notable association between the GA genotype of <em>ADAM33</em> rs2280091 and mortality rates specifically among individuals infected with the Delta variant.</div></div><div><h3>Conclusions</h3><div>In summary, the prediction of COVID-19 severity could be facilitated through the utilization of the <em>CTLA-4</em> rs5742909 marker. Conversely, in the case of <em>ADAM33</em> rs2280091, such prognostication appears to be contingent upon the specific variants of the SARS-CoV-2 virus.</div></div>","PeriodicalId":16087,"journal":{"name":"Journal of Infection and Public Health","volume":"18 1","pages":"Article 102618"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fulminant non-traumatic Clostridium perfringens necrotizing fasciitis and myonecrosis in a child with acute myeloid leukemia","authors":"Banan Alsowailmi ,&nbsp;Mohammed Alshaalan ,&nbsp;Sameera Al Johani ,&nbsp;Musaed Alharbi","doi":"10.1016/j.jiph.2024.102635","DOIUrl":"10.1016/j.jiph.2024.102635","url":null,"abstract":"<div><div>Necrotizing fasciitis is a potentially life-threatening infection that can lead to rapid muscular and fascial necrosis, often resulting in sepsis. In addition to the rapid disease progression, diagnosing this disease in children can be challenging as they cannot accurately communicate their symptoms. Spontaneous necrotizing fasciitis secondary to <em>Clostridial</em> infection has rarely been described in the literature but occurs in neutropenic patients with significant morbidity and mortality from myonecrosis and gas gangrene. This case report describes fulminant nontraumatic necrotizing fasciitis in a 15-month-old child receiving chemotherapy for acute myeloid leukemia. The child had risk factors, including neutropenia, immunosuppression, and prior antibiotic use, which possibly contributed to <em>Clostridial</em> colonization of the gastrointestinal tract and eventual hematogenous spread. He rapidly developed progressive swelling and erythema of the right thigh after venous phlebotomy. Imaging revealed subcutaneous emphysema with evidence of necrotizing fasciitis and deep compartmental collections. The disease spread rapidly, involving the scrotum and lower abdominal wall. Despite parenteral antibiotics and extensive surgical debridement, the patient’s condition deteriorated rapidly, with refractory septic shock and its sequelae, and he eventually died. This case study highlights the critical importance of prompt response to any suspicion of necrotizing fasciitis in immunocompromised pediatric patients to prevent life-threatening complications.</div></div>","PeriodicalId":16087,"journal":{"name":"Journal of Infection and Public Health","volume":"18 3","pages":"Article 102635"},"PeriodicalIF":4.7,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends and gaps in hydroxychloroquine and COVID-19 research (2020–2023): Performance and conceptual mapping","authors":"Abdullah Algaissi ,&nbsp;Manal Mohamed Elhassan Taha ,&nbsp;Edrous Alamer ,&nbsp;Nader Kameli ,&nbsp;Abdulaziz Alhazmi ,&nbsp;Nizar Khamjan ,&nbsp;Siddig Ibrahim Abdelwahab","doi":"10.1016/j.jiph.2024.102623","DOIUrl":"10.1016/j.jiph.2024.102623","url":null,"abstract":"<div><h3>Background</h3><div>Hydroxychloroquine and Chloroquine (CQ) and Hydroxychloroquine (HCQ) are antimalarial drugs with well-known anti-inflammatory and antiviral effects used to treat various diseases, with few side effects. After COVID-19 emergence, numerous researches from around the world have examined the potential of using CQ or HCQ as potential treatment of COVID-19. However, conflicting outcomes have been found in COVID-19 clinical trials after treatment with CQ or HCQ. This study aims to evaluate research on CQ and HCQ for COVID-19 treatment and prophylaxis control using bibliometric methods.</div></div><div><h3>Methods</h3><div>We analyzed bibliometric data on HCQ and COVID-19 (HCQ-C19) quantitatively and semantically (2020–2023) using the Scopus database VOSviewer, Bibliometrix, and MS Excel.</div></div><div><h3>Results</h3><div>Analyses of 7471 original and conference articles revealed that the total number of publications has continually increased. The country producing the most articles in this field was the United States, followed by Italy, India, and Spain. The top-productive authors on HCQ-C19 are Mussini, C., and Raoult, D. (Italy) with 23 and 21 articles, respectively. The top-impactful organization is IHU Méditerranée Infection, France. A Bibliometrix’s network analysis based on the co-occurrence of keywords revealed the following themes HCQ-C19, including \"clinical research/practice,\" \"COVID-19,\" \"thrombosis,\" \"HCQ,\" \"epidemiology,\" and \"infectious disease.\"</div></div><div><h3>Conclusion</h3><div>In conclusion, the analysis reveals a growing interest in HCQ-C19 research. Prominent contributions come from the United States, Italy, India, and Spain. Key themes include clinical research/practice, COVID-19, thrombosis, HCQ, epidemiology, and infectious disease. Future recommendations include conducting well-designed clinical trials and fostering collaborative interdisciplinary efforts.</div></div>","PeriodicalId":16087,"journal":{"name":"Journal of Infection and Public Health","volume":"18 3","pages":"Article 102623"},"PeriodicalIF":4.7,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pertussis clinical profile shift, severity, prediction in a tertiary hospital: A comparative study before, during, and after COVID-19 in Southern China","authors":"Shufeng Tian ,&nbsp;Yulan Chen ,&nbsp;Qiru Su ,&nbsp;Biao Sun ,&nbsp;Zengrui Lin ,&nbsp;Yuchun Long ,&nbsp;Hongmei Wang ,&nbsp;Cuijuan Liao ,&nbsp;Ying Zhang ,&nbsp;Jinjun Zheng ,&nbsp;Lvjun Chen ,&nbsp;Song Guan ,&nbsp;Sen Wang ,&nbsp;Xinlei Xu ,&nbsp;Jingwen Ai ,&nbsp;Wenhong Zhang ,&nbsp;Jikui Deng","doi":"10.1016/j.jiph.2024.102610","DOIUrl":"10.1016/j.jiph.2024.102610","url":null,"abstract":"<div><h3>Objective</h3><div>To analyze the epidemiological characteristics, clinical manifestations, antimicrobial resistance and develop a predictive model for severe pertussis spanning five years – before, during, and after the COVID-19 pandemic – in Shenzhen children’s hospital in southern China, aiming to provide insights into the pandemic impact and control measures on the pertussis disease profile.</div></div><div><h3>Methods</h3><div>Demographic, clinical, vaccination, and laboratory data were collected for patients who tested positive for pertussis by polymerase chain reaction and/or culture from January 1, 2019, to March 30, 2024. Analysis included changes in demographic and clinical features, indicators of severe cases, and resistance patterns over the study period.</div></div><div><h3>Results</h3><div>During this period, 3963 patients were diagnosed, with 79 severe (PICU admitted) cases; 1433 isolates underwent antimicrobial susceptibility testing. In late 2023, pertussis cases began to increase. From 2019 to 2024, the proportion of cases among 4–6 year olds rose from 4.9 % to 28.6 %, and among 7–11 year olds from 0.7 % to 21.2 %. Macrolide resistance surged from 46.5 % in 2019 to 97.3 % in 2024, with 80 % of resistant hospitalized cases initially treated with macrolides. Clinical severity and co-infection increased post-pandemic, with a larger number of cases necessitating antibiotic changes and enhanced supportive care. Vaccination protected against severe disease. Indicators such as white blood cell count, lymphocyte to neutrophil ratio, platelet count, cyanosis and pneumonia predicted disease severity.</div></div><div><h3>Conclusions</h3><div>Post-pandemic, pertussis cases shifted from infants to school-aged children, with increased clinical severity and high macrolide resistance. Urgent measures are needed to optimize vaccination schedules and develop management strategies addressing and changing epidemiological patterns.</div></div>","PeriodicalId":16087,"journal":{"name":"Journal of Infection and Public Health","volume":"18 1","pages":"Article 102610"},"PeriodicalIF":4.7,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142758942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regional heterogeneity of malaria healthcare seeking and diagnosis in China (2017–2022): Implications in preventing re-establishment of malaria transmission","authors":"Jian-hai Yin ,&nbsp;Li Zhang ,&nbsp;Bo-yu Yi ,&nbsp;Shui-sen Zhou ,&nbsp;Zhi-gui Xia","doi":"10.1016/j.jiph.2024.102601","DOIUrl":"10.1016/j.jiph.2024.102601","url":null,"abstract":"<div><h3>Background</h3><div>Enhancing regional collaboration in malaria prevention and control is a pivotal strategy for malaria control and elimination in China. The objective of this study is to examine the regional heterogeneity of malaria healthcare-seeking behaviors and diagnosis across various regions in China from 2017 to 2022.</div></div><div><h3>Methods</h3><div>Individual case data from national malaria surveillance databases were utilized. An analysis was conducted to discern the regional variations in the healthcare-seeking behaviors and diagnosis among regions.</div></div><div><h3>Results</h3><div>From 2017 to 2022, a total of 10,943 malaria cases were reported in China, predominantly imported cases (10,929), with significant variations in the distribution of different <em>Plasmodium</em> species among regions (<em>P</em> &lt; 0.001) and annually (<em>P</em> &lt; 0.001). There was a notable lack of timeliness in healthcare seeking (56.1 %) and case confirmation (67.3 %) with substantial regional disparities (<em>P</em> &lt; 0.001). These delays predominantly occurred in county and prefectural-level medical institutions (<em>P</em> &lt; 0.001), where misidentification of <em>Plasmodium</em> species was also prevalent (<em>P</em> &lt; 0.001). Furthermore, an initial diagnosis of malaria was observed in 76.6 % of cases (<em>P</em> &lt; 0.001), yet 87.8 % of malaria cases were ultimately confirmed correctly (<em>P</em> &lt; 0.001). Notably, <em>P. ovale</em> (21.0 %) and <em>P. malariae</em> (10.8 %) were easily misidentified as <em>P. vivax</em> (<em>P</em> &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>The development of regional-specific interventions is essential to raise public awareness regarding malaria-related knowledge and to enhance the vigilance of health workers and their capacity of malaria testing. This will strengthen the nation’s malaria surveillance and response system. Concurrently, fostering technological innovations for the rapid and precise identification of <em>Plasmodium</em> species, along with effective coordination of cross-regional mechanisms, is imperative to prevent re-establishment of malaria transmission in China.</div></div>","PeriodicalId":16087,"journal":{"name":"Journal of Infection and Public Health","volume":"18 1","pages":"Article 102601"},"PeriodicalIF":4.7,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142703736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mapping trends and hotspots of research on COVID-19 vaccine effectiveness: A comprehensive bibliometric analysis of global research","authors":"Jomana W. Alsulaiman ,&nbsp;Abdallah Alzoubi ,&nbsp;Ahmad Alrawashdeh ,&nbsp;Arwa M. Al-Dekah ,&nbsp;Sara Abubaker ,&nbsp;Wajdi Amayreh ,&nbsp;Waleed M. Sweileh ,&nbsp;Hamed M. Alzoubi ,&nbsp;Khalid A. Kheirallah","doi":"10.1016/j.jiph.2024.102597","DOIUrl":"10.1016/j.jiph.2024.102597","url":null,"abstract":"<div><h3>Background</h3><div>With an ever growing and expanding body of literature on the newly developed vaccines against the COVID-19, there is an urgent need for a comprehensive analysis of the current state of research on vaccine effectiveness (VE). This study conducted a comprehensive bibliometric analysis to critically examine the productivity and impact of retrieved publications on COVID-19 VE and to predict the future directions of research in the field.</div></div><div><h3>Methods</h3><div>The global literature on COVID-19 VE from 2021 to 2024 was extracted from the VIEW-hub website. Using bibliometric analysis tools, specifically Microsoft Excel, the R package \"bibliometrix, biblioshiny\" and VOSviewer, we analyzed publications for trends in productivity, citations, and global collaboration. Key metrics assessed include publication and citation trends, influential authors, collaborative networks, and thematic evolution, offering a comprehensive view of the research landscape on COVID-19 VE.</div></div><div><h3>Results</h3><div>A total of 490 publications were authored by 5031 authors from 934 institutions and 78 countries and published in 119 journals. Most retrieved publications were original articles (99.6 %). The United States was the most productive country with 205 publications (41.8 %). Global research collaborations were mainly within developed countries. Analysis of the thematic evolution of the field illustrated changing research focus over three distinct time clusters. Throughout 2021, studies were focused on outlining infection prevention and control measures, as well as examining the efficacy of novel mRNA vaccines. In 2022, the linchpin of research was shifted towards dissecting the epidemiological correlates of the pandemic in light of the widespread use of vaccines. The final cluster showed special emphasis on the new variants of COVID-19 and the long-term outcomes of vaccines.</div></div><div><h3>Conclusion</h3><div>Our study identified geopolitical disparities and weak engagement from developing countries in the ongoing efforts regarding COVID-19 VE. This study can inform researchers, policymakers, and funding agencies as they assess ongoing research and future directions in COVID-19 VE.</div></div>","PeriodicalId":16087,"journal":{"name":"Journal of Infection and Public Health","volume":"18 1","pages":"Article 102597"},"PeriodicalIF":4.7,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142703735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}